Alberto Ambesi-Impiombato

Alberto Ambesi-Impiombato

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Alberto Ambesi-Impiombato

Alberto Ambesi-Impiombato

Publications by authors named "Alberto Ambesi-Impiombato"

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Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia.

Cancer Cell 2018 07;34(1):136-147.e6

Institute for Cancer Genetics, Columbia University, New York, NY 10032, USA; Department of Systems Biology, Columbia University, New York, NY 10032, USA; Department of Pediatrics, Columbia University Medical Center, 1130 St. Nicholas Avenue, ICRC 402, New York, NY 10032, USA; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049837PMC
July 2018

RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis.

Cancer Cell 2018 02 2;33(2):259-273.e7. Epub 2018 Feb 2.

Institute for Cancer Genetics, Columbia University, New York, NY 10032, USA; Department of Pathology and Cell Biology, Columbia University Medical Center, 1130 St Nicholas Avenue, ICRC-401B, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811310PMC
February 2018

Therapeutic targeting of HES1 transcriptional programs in T-ALL.

Blood 2015 Apr 17;125(18):2806-14. Epub 2015 Mar 17.

Institute for Cancer Genetics, Columbia University, New York, NY; Department of Pathology and Department of Pediatrics, Columbia University Medical Center, New York, NY.

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http://dx.doi.org/10.1182/blood-2014-10-608448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424629PMC
April 2015

A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia.

Nat Med 2014 Oct 7;20(10):1130-7. Epub 2014 Sep 7.

1] Institute for Cancer Genetics, Columbia University, New York, New York, USA. [2] Department of Pathology, Columbia University Medical Center, New York, New York, USA. [3] Department of Pediatrics, Columbia University Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1038/nm.3665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192073PMC
October 2014

Small Molecule that Reverses Dexamethasone Resistance in T-cell Acute Lymphoblastic Leukemia (T-ALL).

ACS Med Chem Lett 2014 Jul 25;5(7):754-9. Epub 2014 Apr 25.

Department of Biological Sciences, Department of Chemistry, and Howard Hughes Medical Institute, Columbia University , 1208 Northwest Corner Building, 12th Floor, 550 West 120th Street, MC 4846, New York, New York 10027 United States ; Department of Biological Sciences, Department of Chemistry, and Howard Hughes Medical Institute, Columbia University , 1208 Northwest Corner Building, 12th Floor, 550 West 120th Street, MC 4846, New York, New York 10027 United States ; Department of Biological Sciences, Department of Chemistry, and Howard Hughes Medical Institute, Columbia University , 1208 Northwest Corner Building, 12th Floor, 550 West 120th Street, MC 4846, New York, New York 10027 United States ; Department of Systems Biology, Columbia University Medical Center , and Institute for Cancer Genetics, Columbia University , New York, New York 10032 United States.

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http://dx.doi.org/10.1021/ml500044gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094258PMC
July 2014

Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas.

Nat Genet 2014 Feb 12;46(2):166-70. Epub 2014 Jan 12.

1] Institute for Cancer Genetics, Columbia University, New York, New York, USA. [2] Department of Pathology, Columbia University Medical Center, New York, New York, USA. [3] Department of Pediatrics, Columbia University Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1038/ng.2873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963408PMC
February 2014

Pattern of acute induction of Homer1a gene is preserved after chronic treatment with first- and second-generation antipsychotics: effect of short-term drug discontinuation and comparison with Homer1a-interacting genes.

J Psychopharmacol 2011 Jul 10;25(7):875-87. Epub 2010 Feb 10.

Laboratory of Molecular Psychiatry and Psychopharmacotherapy, Section of Psychiatry, Department of Neuroscience, University School of Medicine 'Federico II', Naples, Italy.

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http://dx.doi.org/10.1177/0269881109358199DOI Listing
July 2011

The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia.

Cancer Cell 2010 Jan 7;17(1):28-40. Epub 2010 Jan 7.

Institute for Cancer Genetics and the Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.ccr.2009.11.019DOI Listing
January 2010

Dopamine receptor subtypes contribution to Homer1a induction: insights into antipsychotic molecular action.

Prog Neuropsychopharmacol Biol Psychiatry 2009 Aug 23;33(5):813-21. Epub 2009 Feb 23.

Laboratory of Molecular Psychiatry and Psychopharmacotherapeutics, Section of Psychiatry, Department of Neurosciences, University School of Medicine Federico II, Via Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1016/j.pnpbp.2009.02.009DOI Listing
August 2009

Differential expression of Homer 1 gene by acute and chronic administration of antipsychotics and dopamine transporter inhibitors in the rat forebrain.

Synapse 2007 Jun;61(6):429-39

Laboratory of Molecular Psychiatry and Psychopharmacotherapy, Section of Psychiatry, Department of Neuroscience, University School of Medicine Federico II, Naples, Italy.

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http://dx.doi.org/10.1002/syn.20385DOI Listing
June 2007

Ketamine-related expression of glutamatergic postsynaptic density genes: possible implications in psychosis.

Neurosci Lett 2007 Apr 25;416(1):1-5. Epub 2007 Jan 25.

Laboratory of Molecular Psychiatry and Psychopharmacotherapy, Section of Psychiatry, Department of Neuroscience, University School of Medicine Federico II, Via Pansini 5, Naples, Italy.

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http://dx.doi.org/10.1016/j.neulet.2007.01.041DOI Listing
April 2007

How to infer gene networks from expression profiles.

Mol Syst Biol 2007 13;3:78. Epub 2007 Feb 13.

Telethon Institute of Genetics and Medicine, Via P Castellino, Naples, Italy.

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http://dx.doi.org/10.1038/msb4100120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828749PMC
March 2007

Computational framework for the prediction of transcription factor binding sites by multiple data integration.

BMC Neurosci 2006 Oct 30;7 Suppl 1:S8. Epub 2006 Oct 30.

TIGEM, Telethon Institute of Genetics and Medicine, Naples, Italy.

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http://dx.doi.org/10.1186/1471-2202-7-S1-S8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1775048PMC
October 2006

Method for quantitative in situ hybridization histochemistry and image analysis applied for Homer1a gene expression in rat brain.

Brain Res Brain Res Protoc 2003 Jul;11(3):189-96

Laboratory of Molecular Psychiatry and Psychopharmacotherapy, Section of Psychiatry, Department of Neuroscience and Behavioral Science University School of Medicine "Federico II", Edificio 18, Via Pansini 5, 80131 Naples, Italy.

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July 2003

Homer 1a gene expression modulation by antipsychotic drugs: involvement of the glutamate metabotropic system and effects of D-cycloserine.

Neuropsychopharmacology 2002 Dec;27(6):906-13

Department of Neuroscience and Behavioral Sciences, Laboratory of Molecular Psychiatry and Psychopharmacotherapy, Section of Psychiatry, University School of Medicine Federico II, Naples, Italy.

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http://dx.doi.org/10.1016/S0893-133X(02)00371-8DOI Listing
December 2002

Acute administration of antipsychotics modulates Homer striatal gene expression differentially.

Brain Res Mol Brain Res 2002 Jan;98(1-2):124-9

Department of Neuroscience and Behavioral Sciences, Section of Psychiatry, University School of Medicine Federico II, Edificio 18, Via Pansini 5, 80131, Naples, Italy.

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http://dx.doi.org/10.1016/s0169-328x(01)00327-8DOI Listing
January 2002