Albert de la Chapelle

Albert de la Chapelle

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Albert de la Chapelle

Publications by authors named "Albert de la Chapelle"

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Identification of Rare Variants Predisposing to Thyroid Cancer.

Thyroid 2019 Jul 13;29(7):946-955. Epub 2019 May 13.

1Human Cancer Genetics Program and Department of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1089/thy.2018.0736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648188PMC
July 2019

Fine mapping of 14q13 reveals novel variants associated with different histological subtypes of papillary thyroid carcinoma.

Int J Cancer 2019 02 3;144(3):503-512. Epub 2018 Dec 3.

Human Cancer Genetics Program and Department of Cancer Biology and Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH.

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http://doi.wiley.com/10.1002/ijc.31933
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http://dx.doi.org/10.1002/ijc.31933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294684PMC
February 2019

Discovery of common and rare genetic risk variants for colorectal cancer.

Authors:
Jeroen R Huyghe Stephanie A Bien Tabitha A Harrison Hyun Min Kang Sai Chen Stephanie L Schmit David V Conti Conghui Qu Jihyoun Jeon Christopher K Edlund Peyton Greenside Michael Wainberg Fredrick R Schumacher Joshua D Smith David M Levine Sarah C Nelson Nasa A Sinnott-Armstrong Demetrius Albanes M Henar Alonso Kristin Anderson Coral Arnau-Collell Volker Arndt Christina Bamia Barbara L Banbury John A Baron Sonja I Berndt Stéphane Bézieau D Timothy Bishop Juergen Boehm Heiner Boeing Hermann Brenner Stefanie Brezina Stephan Buch Daniel D Buchanan Andrea Burnett-Hartman Katja Butterbach Bette J Caan Peter T Campbell Christopher S Carlson Sergi Castellví-Bel Andrew T Chan Jenny Chang-Claude Stephen J Chanock Maria-Dolores Chirlaque Sang Hee Cho Charles M Connolly Amanda J Cross Katarina Cuk Keith R Curtis Albert de la Chapelle Kimberly F Doheny David Duggan Douglas F Easton Sjoerd G Elias Faye Elliott Dallas R English Edith J M Feskens Jane C Figueiredo Rocky Fischer Liesel M FitzGerald David Forman Manish Gala Steven Gallinger W James Gauderman Graham G Giles Elizabeth Gillanders Jian Gong Phyllis J Goodman William M Grady John S Grove Andrea Gsur Marc J Gunter Robert W Haile Jochen Hampe Heather Hampel Sophia Harlid Richard B Hayes Philipp Hofer Michael Hoffmeister John L Hopper Wan-Ling Hsu Wen-Yi Huang Thomas J Hudson David J Hunter Gemma Ibañez-Sanz Gregory E Idos Roxann Ingersoll Rebecca D Jackson Eric J Jacobs Mark A Jenkins Amit D Joshi Corinne E Joshu Temitope O Keku Timothy J Key Hyeong Rok Kim Emiko Kobayashi Laurence N Kolonel Charles Kooperberg Tilman Kühn Sébastien Küry Sun-Seog Kweon Susanna C Larsson Cecelia A Laurie Loic Le Marchand Suzanne M Leal Soo Chin Lee Flavio Lejbkowicz Mathieu Lemire Christopher I Li Li Li Wolfgang Lieb Yi Lin Annika Lindblom Noralane M Lindor Hua Ling Tin L Louie Satu Männistö Sanford D Markowitz Vicente Martín Giovanna Masala Caroline E McNeil Marilena Melas Roger L Milne Lorena Moreno Neil Murphy Robin Myte Alessio Naccarati Polly A Newcomb Kenneth Offit Shuji Ogino N Charlotte Onland-Moret Barbara Pardini Patrick S Parfrey Rachel Pearlman Vittorio Perduca Paul D P Pharoah Mila Pinchev Elizabeth A Platz Ross L Prentice Elizabeth Pugh Leon Raskin Gad Rennert Hedy S Rennert Elio Riboli Miguel Rodríguez-Barranco Jane Romm Lori C Sakoda Clemens Schafmayer Robert E Schoen Daniela Seminara Mitul Shah Tameka Shelford Min-Ho Shin Katerina Shulman Sabina Sieri Martha L Slattery Melissa C Southey Zsofia K Stadler Christa Stegmaier Yu-Ru Su Catherine M Tangen Stephen N Thibodeau Duncan C Thomas Sushma S Thomas Amanda E Toland Antonia Trichopoulou Cornelia M Ulrich David J Van Den Berg Franzel J B van Duijnhoven Bethany Van Guelpen Henk van Kranen Joseph Vijai Kala Visvanathan Pavel Vodicka Ludmila Vodickova Veronika Vymetalkova Korbinian Weigl Stephanie J Weinstein Emily White Aung Ko Win C Roland Wolf Alicja Wolk Michael O Woods Anna H Wu Syed H Zaidi Brent W Zanke Qing Zhang Wei Zheng Peter C Scacheri John D Potter Michael C Bassik Anshul Kundaje Graham Casey Victor Moreno Goncalo R Abecasis Deborah A Nickerson Stephen B Gruber Li Hsu Ulrike Peters

Nat Genet 2019 01 3;51(1):76-87. Epub 2018 Dec 3.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://www.nature.com/articles/s41588-018-0286-6
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http://dx.doi.org/10.1038/s41588-018-0286-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358437PMC
January 2019

Cancer Risks for PMS2-Associated Lynch Syndrome.

J Clin Oncol 2018 Oct 30;36(29):2961-2968. Epub 2018 Aug 30.

Sanne W. ten Broeke, Heleen M. van der Klift, Carli M.J. Tops, Manon Suerink, Frederik J. Hes, Hans F.A. Vasen, Juul T. Wijnen, and Maartje Nielsen, Leiden University Medical Center, Leiden; Encarna Gomez Garcia, Maastricht University Medical Center, Maastricht; Nicoline Hoogerbrugge, Arjen R. Mensenkamp, and Liesbeth Spruijt, Radboud University Medical Center, Nijmegen; Tom G.W. Letteboer, University Medical Center, Utrecht; Theo A.M. van Os and Egbert J.W. Redeker, Academic Medical Center, Amsterdam; Maran J.W. Olderode-Berends and Yvonne J. Vos, University of Groningen; University Medical Center Groningen, Groningen; Anja Wagner, Erasmus Medical Center, Rotterdam, the Netherlands; Stefan Aretz, University of Bonn; University Hospital Bonn, Bonn; Christoph Engel, Leipzig University; Medizinisch Genetisches Zentrum Bayerstr, Leipzig; Magnus von Knebel Doeberitz, University of Heidelberg; German Cancer Research Center, Heidelberg; Pål Møller, University of Witten-Herdecke, Wuppertal; Nils Rahner, Heinrich-Heine-University, Düsseldorf; Hans K. Schackert, Technische Universität Dresden, Dresden; Verena Steinke-Lange, Medizinische Klinik und Poliklinik IV Campus Innenstadt, Klinikum der Universität München, Munich, Germany; Pål Møller, The Norwegian Radium Hospital; Oslo University Hospital, Oslo, Norway; Inge Bernstein, Hvidovre Hospital, Hvidovre, and Aalborg University Hospital, Aalborg, Denmark; Daniel D. Buchanan, Mark Clendenning, John L. Hopper, Mark A. Jenkins, Christophe Rosty, Ingrid Winship, and Aung Ko Win, The University of Melbourne; Daniel D. Buchanan, Ingrid Winship, and Aung Ko Win, Royal Melbourne Hospital, Parkville, Melbourne, Victoria; Rodney Scott, University of Newcastle, Newcastle, New South Wales, Australia; Albert de la Chapelle, Heather L. Hampel, Rachel Pearlman, and Leigha Senter, The Ohio State University Comprehensive Cancer Center, Columbus, OH; Gabriel Capella and Marta Pineda, Institut d'Investigació Biomédica de Bellvitge, Barcelona, Spain; Steven Gallinger, Mount Sinai Hospital, Toronto, Ontario, Canada; Jane C. Figueiredo and Robert Haile, Cedars-Sinai Medical Center, Los Angeles, CA; Loic Le Marchand, University of Hawaii Cancer Center, Honolulu, HI; Annika Lindblom, Karolinska Institutet; Karolinska University Hospital, Stockholm, Sweden; Noralane M. Lindor, Mayo Clinic Arizona, Scottsdale, AZ; Polly A. Newcomb, Fred Hutchinson Cancer Research Center; University of Washington, Seattle, WA; and Stephen Thibodeau, Mayo Clinic, Rochester, MN.

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http://ascopubs.org/doi/10.1200/JCO.2018.78.4777
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http://dx.doi.org/10.1200/JCO.2018.78.4777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349460PMC
October 2018

The role of SMAD3 in the genetic predisposition to papillary thyroid carcinoma.

Genet Med 2018 09 4;20(9):927-935. Epub 2018 Jan 4.

Human Cancer Genetics Program and Department of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA.

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http://dx.doi.org/10.1038/gim.2017.224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030507PMC
September 2018

Identification of a Recurrent LMO7-BRAF Fusion in Papillary Thyroid Carcinoma.

Thyroid 2018 06 16;28(6):748-754. Epub 2018 May 16.

1 Department of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, The Ohio State University , Columbus, Ohio.

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http://dx.doi.org/10.1089/thy.2017.0258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994666PMC
June 2018

The Role of NRG1 in the Predisposition to Papillary Thyroid Carcinoma.

J Clin Endocrinol Metab 2018 04;103(4):1369-1379

Department of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1210/jc.2017-01798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018707PMC
April 2018

The early years of the ESHG leading to the reform of 1988 and the spirit of the Sestri Levante school.

Eur J Hum Genet 2017 12;25(s2):S6-S12

Human Cancer Genetics Program, The Ohio State University, Columbus, Ohio, USA.

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http://dx.doi.org/10.1038/ejhg.2017.142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763252PMC
December 2017

Mutation Frequencies in Patients With Early-Onset Colorectal Cancer-Reply.

JAMA Oncol 2017 11;3(11):1587

Ohio State University Comprehensive Cancer Center, Department of Internal Medicine, Ohio State University Wexner Medical Center, Columbus.

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http://dx.doi.org/10.1001/jamaoncol.2017.1744DOI Listing
November 2017

Variants in microRNA genes in familial papillary thyroid carcinoma.

Oncotarget 2017 Jan;8(4):6475-6482

Department of Cancer Biology and Genetics, The Ohio State University Wexner Medical Center and Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.18632/oncotarget.14129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351646PMC
January 2017

MYH9 binds to lncRNA gene PTCSC2 and regulates FOXE1 in the 9q22 thyroid cancer risk locus.

Proc Natl Acad Sci U S A 2017 01 3;114(3):474-479. Epub 2017 Jan 3.

Human Cancer Genetics Program, The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210;

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http://dx.doi.org/10.1073/pnas.1619917114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5255605PMC
January 2017

Genome-Wide Expression Screening Discloses Long Noncoding RNAs Involved in Thyroid Carcinogenesis.

J Clin Endocrinol Metab 2016 Nov 26;101(11):4005-4013. Epub 2016 Jul 26.

Human Cancer Genetics Program and Department of Cancer Biology and Genetics (S.L., W.L., P.B., L.S., A.d.l.C., H.H.) and Departments of Internal Medicine (P.Y., P.B., L.S., M.D.R.) and Physics (R.B.), The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210.

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http://dx.doi.org/10.1210/jc.2016-1991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095253PMC
November 2016

The Olympic Games and Athletic Sex Assignment.

JAMA 2016 Oct;316(13):1359-1360

Human Cancer Genetics Program, Comprehensive Cancer Center, Ohio State University, Columbus.

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http://dx.doi.org/10.1001/jama.2016.11850DOI Listing
October 2016

Patients with colorectal cancer associated with Lynch syndrome and MLH1 promoter hypermethylation have similar prognoses.

Genet Med 2016 09 11;18(9):863-8. Epub 2016 Feb 11.

Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, Ohio, USA.

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http://dx.doi.org/10.1038/gim.2015.184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489337PMC
September 2016

Primary Cell Culture Systems for Human Thyroid Studies.

Thyroid 2016 08 6;26(8):1131-40. Epub 2016 Jul 6.

1 Human Cancer Genetics Program and Department of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, The Ohio State University , Columbus, Ohio.

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http://dx.doi.org/10.1089/thy.2015.0518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976228PMC
August 2016

HABP2 G534E Variant in Papillary Thyroid Carcinoma.

PLoS One 2016 8;11(1):e0146315. Epub 2016 Jan 8.

Department of Molecular Virology, Immunology and Medical Genetics, Ohio State University Wexner Medical Center and Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0146315PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706330PMC
July 2016

Colon Cancer Germline Genetics: The Unbelievable Year 1993 and Thereafter.

Cancer Res 2016 07;76(14):4025-7

The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1637DOI Listing
July 2016

Structural characterization of NRAS isoform 5.

Protein Sci 2016 May 24;25(5):1069-74. Epub 2016 Mar 24.

The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1002/pro.2916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838646PMC
May 2016

HABP2 Mutation and Nonmedullary Thyroid Cancer.

N Engl J Med 2015 11;373(21):2086

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http://dx.doi.org/10.1056/NEJMc1511631DOI Listing
November 2015

PTCSC3 Is Involved in Papillary Thyroid Carcinoma Development by Modulating S100A4 Gene Expression.

J Clin Endocrinol Metab 2015 Oct 14;100(10):E1370-7. Epub 2015 Aug 14.

Human Cancer Genetics Program, Comprehensive Cancer Center (J.J., A.T., S.L., A.E., J.T., H.H., H.S.R., W.L., R.N., A.d.l.C.), The Ohio State University, Columbus, Ohio, 43210; and Department of Endocrinology and Internal Medicine (J.J., K.S.), Medical University of Gdansk, Poland.

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http://dx.doi.org/10.1210/jc.2015-2247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596031PMC
October 2015

A germline mutation in SRRM2, a splicing factor gene, is implicated in papillary thyroid carcinoma predisposition.

Sci Rep 2015 Jul 2;5:10566. Epub 2015 Jul 2.

Department of Molecular Virology, Immunology and Medical Genetics, Ohio State University Wexner Medical Center and Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, United States of America.

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http://dx.doi.org/10.1038/srep10566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488885PMC
July 2015

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency.

N Engl J Med 2015 Jun 30;372(26):2509-20. Epub 2015 May 30.

From the Swim Across America Laboratory (D.T.L., J.N.U., B.R.B., L.A.D.), Sidney Kimmel Comprehensive Cancer Center (D.T.L., J.N.U., H.W., H.K., A.D.E., A.D.S., B.S.L., N.S.A., D.L., B.B., R.C.D., D.M.P., N.P., K.W.K., S.Z., B.V., L.A.D.), Ludwig Center and Howard Hughes Medical Institute (B.R.B., A.D.S., N.P., K.W.K., S.Z., B.V., L.A.D.), and the Departments of Radiology (A.Z.) and Pathology (F.B., T.H., R.H.H., L.D.W., N.C., T.C.C., J.M.T., R.A.A., J.R.E.), Johns Hopkins University School of Medicine, Baltimore; Department of Medicine, Stanford University School of Medicine, Stanford, CA (G.A.F.); Providence Cancer Center at Providence Health and Services, Portland, OR (T.S.C.); Department of Medicine, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh (J.J.L.); Bon Secours Cancer Institute, Richmond, VA (S.M.D.); Division of Medical Oncology, Ohio State University Comprehensive Cancer Center-James Cancer Center and Solove Research Institute, and Human Cancer Genetics Program, Ohio State University Comprehensive Cancer Center, Columbus (R.M.G., A.C.); and Merck, Kenilworth, NJ, and North Wales, PA (M.K.).

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http://dx.doi.org/10.1056/NEJMoa1500596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481136PMC
June 2015

Immunoglobulin transcript sequence and somatic hypermutation computation from unselected RNA-seq reads in chronic lymphocytic leukemia.

Proc Natl Acad Sci U S A 2015 Apr 18;112(14):4322-7. Epub 2015 Mar 18.

Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH 43210; College of Pharmacy, The Ohio State University, Columbus, OH 43210

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http://dx.doi.org/10.1073/pnas.1503587112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394264PMC
April 2015

Genetic predisposition to papillary thyroid carcinoma: involvement of FOXE1, TSHR, and a novel lincRNA gene, PTCSC2.

J Clin Endocrinol Metab 2015 Jan;100(1):E164-72

Human Cancer Genetics Program and Department of Molecular Virology, Immunology, and Medical Genetics (H.H., W.L., S.L., J.J., M.S., R.N., A.d.l.C), and Department of Internal Medicine (R.N.), Ohio State University Comprehensive Cancer Center, the Ohio State University, Columbus, Ohio 43210; and Division of Health and Biomedical Informatics, Department of Preventive Medicine, Robert H. Lurie Comprehensive Cancer Center (R.V.D.), Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611.

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http://dx.doi.org/10.1210/jc.2014-2147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283026PMC
January 2015

Biallelic MUTYH mutations can mimic Lynch syndrome.

Eur J Hum Genet 2014 Nov 12;22(11):1334-7. Epub 2014 Feb 12.

1] Medizinische Klinik und Poliklinik IV, Campus Innenstadt, Klinikum der Universität München, Munich, Germany [2] MGZ - Medizinisch Genetisches Zentrum, Munich, Germany.

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http://dx.doi.org/10.1038/ejhg.2014.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200426PMC
November 2014

Prostate cancer incidence in males with Lynch syndrome.

Genet Med 2014 Jul 16;16(7):553-7. Epub 2014 Jan 16.

Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Medical Center, Columbus, Ohio, USA.

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http://dx.doi.org/10.1038/gim.2013.193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289599PMC
July 2014

Variants in the ATM-CHEK2-BRCA1 axis determine genetic predisposition and clinical presentation of papillary thyroid carcinoma.

Genes Chromosomes Cancer 2014 Jun 6;53(6):516-23. Epub 2014 Mar 6.

Genomic Medicine, Department of General, Transplant, and Liver Surgery, Medical University of Warsaw, Warsaw 02-091, Poland; Centre of New Technologies, CENT, University of Warsaw, Warsaw 02-089, Poland.

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http://dx.doi.org/10.1002/gcc.22162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058861PMC
June 2014

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease.

Authors:
Marco Medici Eleonora Porcu Giorgio Pistis Alexander Teumer Suzanne J Brown Richard A Jensen Rajesh Rawal Greet L Roef Theo S Plantinga Sita H Vermeulen Jari Lahti Matthew J Simmonds Lise Lotte N Husemoen Rachel M Freathy Beverley M Shields Diana Pietzner Rebecca Nagy Linda Broer Layal Chaker Tim I M Korevaar Maria Grazia Plia Cinzia Sala Uwe Völker J Brent Richards Fred C Sweep Christian Gieger Tanguy Corre Eero Kajantie Betina Thuesen Youri E Taes W Edward Visser Andrew T Hattersley Jürgen Kratzsch Alexander Hamilton Wei Li Georg Homuth Monia Lobina Stefano Mariotti Nicole Soranzo Massimiliano Cocca Matthias Nauck Christin Spielhagen Alec Ross Alice Arnold Martijn van de Bunt Sandya Liyanarachchi Margit Heier Hans Jörgen Grabe Corrado Masciullo Tessel E Galesloot Ee M Lim Eva Reischl Peter J Leedman Sandra Lai Alessandro Delitala Alexandra P Bremner David I W Philips John P Beilby Antonella Mulas Matteo Vocale Goncalo Abecasis Tom Forsen Alan James Elisabeth Widen Jennie Hui Holger Prokisch Ernst E Rietzschel Aarno Palotie Peter Feddema Stephen J Fletcher Katharina Schramm Jerome I Rotter Alexander Kluttig Dörte Radke Michela Traglia Gabriela L Surdulescu Huiling He Jayne A Franklyn Daniel Tiller Bijay Vaidya Tim de Meyer Torben Jørgensen Johan G Eriksson Peter C O'Leary Eric Wichmann Ad R Hermus Bruce M Psaty Till Ittermann Albert Hofman Emanuele Bosi David Schlessinger Henri Wallaschofski Nicola Pirastu Yurii S Aulchenko Albert de la Chapelle Romana T Netea-Maier Stephen C L Gough Henriette Meyer Zu Schwabedissen Timothy M Frayling Jean-Marc Kaufman Allan Linneberg Katri Räikkönen Johannes W A Smit Lambertus A Kiemeney Fernando Rivadeneira André G Uitterlinden John P Walsh Christa Meisinger Martin den Heijer Theo J Visser Timothy D Spector Scott G Wilson Henry Völzke Anne Cappola Daniela Toniolo Serena Sanna Silvia Naitza Robin P Peeters

PLoS Genet 2014 Feb 27;10(2):e1004123. Epub 2014 Feb 27.

Department of Internal Medicine, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://repub.eur.nl/pub/65428/REPUB_65428_OA.pdf
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http://dx.plos.org/10.1371/journal.pgen.1004123
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http://dx.doi.org/10.1371/journal.pgen.1004123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937134PMC
February 2014

Cumulative risk impact of five genetic variants associated with papillary thyroid carcinoma.

Thyroid 2013 Dec 29;23(12):1532-40. Epub 2013 Aug 29.

1 Human Cancer Genetics Program and Department of Molecular Virology, Immunology, and Medical Genetics, Ohio State University Comprehensive Cancer Center, The Ohio State University , Columbus, Ohio.

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http://dx.doi.org/10.1089/thy.2013.0102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868253PMC
December 2013

Unraveling the genetic predisposition to differentiated thyroid carcinoma.

J Clin Endocrinol Metab 2013 Oct;98(10):3974-6

MD, PhD, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, 804 Biomedical Research Tower, 410 West 12th Avenue, Columbus, Ohio 43210.

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http://dx.doi.org/10.1210/jc.2013-3494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790612PMC
October 2013

In-depth characterization of the microRNA transcriptome in normal thyroid and papillary thyroid carcinoma.

J Clin Endocrinol Metab 2013 Aug 19;98(8):E1401-9. Epub 2013 Jun 19.

Laboratory of Genomic Medicine, Department of General, Transplant, and Liver Surgery, Medical University of Warsaw, Warsaw 02-097, Poland.

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http://dx.doi.org/10.1210/jc.2013-1214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399477PMC
August 2013

How do we approach the goal of identifying everybody with Lynch syndrome?

Fam Cancer 2013 Jun;12(2):313-7

The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1007/s10689-013-9611-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337020PMC
June 2013

Hereditary intrinsic factor deficiency in chaldeans.

JIMD Rep 2013 18;7:13-8. Epub 2012 Mar 18.

Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, BRT 804, 460W. 12th Ave, Columbus, OH, 43210, USA.

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http://dx.doi.org/10.1007/8904_2012_133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575053PMC
February 2013

Inherited cobalamin malabsorption. Mutations in three genes reveal functional and ethnic patterns.

Orphanet J Rare Dis 2012 Aug 28;7:56. Epub 2012 Aug 28.

Human Cancer Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1186/1750-1172-7-56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462684PMC
August 2012

An American founder mutation in MLH1.

Int J Cancer 2012 May 30;130(9):2088-95. Epub 2011 Aug 30.

Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1002/ijc.26233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266960PMC
May 2012

The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type.

Proc Natl Acad Sci U S A 2012 May 14;109(22):8646-51. Epub 2012 May 14.

Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1073/pnas.1205654109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365219PMC
May 2012

MicroRNA signature in thyroid fine needle aspiration cytology applied to "atypia of undetermined significance" cases.

Thyroid 2012 Jan 2;22(1):9-16. Epub 2011 Dec 2.

Department of Pathology, Arthur G. James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1089/thy.2011.0081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247703PMC
January 2012

MicroRNAs in thyroid cancer.

J Clin Endocrinol Metab 2011 Nov 24;96(11):3326-36. Epub 2011 Aug 24.

Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, 804 Biomedical Research Tower, 460 West 12th Avenue, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1210/jc.2011-1004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410255PMC
November 2011

Telomere length and telomerase reverse transcriptase gene copy number in patients with papillary thyroid carcinoma.

J Clin Endocrinol Metab 2011 Nov 7;96(11):E1876-80. Epub 2011 Sep 7.

Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, 804 Biomedical Research Tower 460 West 12th Avenue Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1210/jc.2011-1643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205886PMC
November 2011

Ancient founder mutation is responsible for Imerslund-Gräsbeck Syndrome among diverse ethnicities.

Orphanet J Rare Dis 2011 Nov 13;6:74. Epub 2011 Nov 13.

Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1186/1750-1172-6-74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226546PMC
November 2011

Thyroid hormone receptor beta (THRB) is a major target gene for microRNAs deregulated in papillary thyroid carcinoma (PTC).

J Clin Endocrinol Metab 2011 Mar 15;96(3):E546-53. Epub 2010 Dec 15.

Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, 804 Biomedical Research Tower, 460 West 12th Avenue, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1210/jc.2010-1594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047217PMC
March 2011

The search for unaffected individuals with Lynch syndrome: do the ends justify the means?

Cancer Prev Res (Phila) 2011 Jan;4(1):1-5

Division of Human Genetics, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, 2001 Polaris Parkway, Columbus, OH 43240, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-10-0345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076593PMC
January 2011

Role of PTPRJ genotype in papillary thyroid carcinoma risk.

Endocr Relat Cancer 2010 Dec 29;17(4):1001-6. Epub 2010 Oct 29.

Dipartimento di Medicina Sperimentale e Clinica, Facoltà di Medicina e Chirurgia, Università degli Studi Magna Græcia di Catanzaro, Campus Salvatore Venuta, Viale Europa, località Germaneto, Catanzaro, Italy.

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https://erc.bioscientifica.com/view/journals/erc/17/4/1001.x
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http://dx.doi.org/10.1677/ERC-10-0143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915780PMC
December 2010

Clinical relevance of microsatellite instability in colorectal cancer.

J Clin Oncol 2010 Jul 1;28(20):3380-7. Epub 2010 Jun 1.

Ohio State University, Comprehensive Cancer Center, Columbus, OH 43210, USA.

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http://ascopubs.org/doi/10.1200/JCO.2009.27.0652
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http://dx.doi.org/10.1200/JCO.2009.27.0652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903331PMC
July 2010

Epitope-positive truncating MLH1 mutation and loss of PMS2: implications for IHC-directed genetic testing for Lynch syndrome.

Fam Cancer 2009 12;8(4):501-4. Epub 2009 Aug 12.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine and Siteman Cancer Center, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1007/s10689-009-9276-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771133PMC
January 2010

Low cancer incidence rates in Ohio Amish.

Cancer Causes Control 2010 Jan 25;21(1):69-75. Epub 2009 Sep 25.

Division of Human Genetics, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1007/s10552-009-9435-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308689PMC
January 2010

Polymorphic mature microRNAs from passenger strand of pre-miR-146a contribute to thyroid cancer.

Proc Natl Acad Sci U S A 2009 Feb 21;106(5):1502-5. Epub 2009 Jan 21.

Human Cancer Genetics Program, Comprehensive Cancer Center and Division of Endocrinology, Ohio State University, Columbus, OH 43210, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0812591106
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http://dx.doi.org/10.1073/pnas.0812591106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635764PMC
February 2009

A susceptibility locus for papillary thyroid carcinoma on chromosome 8q24.

Cancer Res 2009 Jan;69(2):625-31

Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-1071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634601PMC
January 2009

Tgfbr1 haploinsufficiency is a potent modifier of colorectal cancer development.

Cancer Res 2009 Jan;69(2):678-86

Department of Medicine, Division of Hematology/Oncology, Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, Alabama 35294-3300, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-3980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668823PMC
January 2009