Albert Tenesa

Albert Tenesa

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Albert Tenesa

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Indirect assortative mating for human disease and longevity.

Heredity (Edinb) 2019 Aug 5;123(2):106-116. Epub 2019 Feb 5.

The Roslin Institute, Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush Campus, Midlothian, Edinburgh, EH25 9RG, Scotland.

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http://dx.doi.org/10.1038/s41437-019-0185-3DOI Listing
August 2019

Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability.

Nat Commun 2018 12 10;9(1):5271. Epub 2018 Dec 10.

MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK.

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http://dx.doi.org/10.1038/s41467-018-07691-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288091PMC
December 2018

An atlas of genetic associations in UK Biobank.

Nat Genet 2018 11 22;50(11):1593-1599. Epub 2018 Oct 22.

The Roslin Institute, Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Midlothian, UK.

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http://www.nature.com/articles/s41588-018-0248-z
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http://dx.doi.org/10.1038/s41588-018-0248-zDOI Listing
November 2018

Genome-wide scan of the effect of common nsSNPs on colorectal cancer survival outcome.

Br J Cancer 2018 Oct 21;119(8):988-993. Epub 2018 Aug 21.

Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, University of Edinburgh and MRC Human Genetics Unit Western General Hospital Edinburgh, Edinburgh, EH4 2XU, UK.

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http://dx.doi.org/10.1038/s41416-018-0117-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203849PMC
October 2018

Improved Genetic Profiling of Anthropometric Traits Using a Big Data Approach.

PLoS One 2016 15;11(12):e0166755. Epub 2016 Dec 15.

The Roslin Institute, Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush Campus, Midlothian, Scotland, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0166755PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157980PMC
June 2017

Evidence of epigenetic admixture in the Colombian population.

Hum Mol Genet 2017 02;26(3):501-508

The Roslin Institute, Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush Campus, Midlothian, Scotland, UK.

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http://dx.doi.org/10.1093/hmg/ddw407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409088PMC
February 2017

Imputation of DNA Methylation Levels in the Brain Implicates a Risk Factor for Parkinson's Disease.

Genetics 2016 Oct 27;204(2):771-781. Epub 2016 Jul 27.

Roslin Institute, University of Edinburgh, Edinburgh EH25 9RG, United Kingdom Medical Research Council Human Genetics Unit at the Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, United Kingdom

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http://dx.doi.org/10.1534/genetics.115.185967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068861PMC
October 2016

Evaluating the contribution of genetics and familial shared environment to common disease using the UK Biobank.

Nat Genet 2016 09 18;48(9):980-3. Epub 2016 Jul 18.

Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian, UK.

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http://www.nature.com/articles/ng.3618
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http://dx.doi.org/10.1038/ng.3618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989924PMC
September 2016

Evidence for sex-specific genetic architectures across a spectrum of human complex traits.

Genome Biol 2016 07 29;17(1):166. Epub 2016 Jul 29.

The Roslin Institute, Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush Campus, Midlothian, EH25 9RG, Scotland, UK.

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http://dx.doi.org/10.1186/s13059-016-1025-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965887PMC
July 2016

Modulation of genetic associations with serum urate levels by body-mass-index in humans.

Authors:
Jennifer E Huffman Eva Albrecht Alexander Teumer Massimo Mangino Karen Kapur Toby Johnson Zoltán Kutalik Nicola Pirastu Giorgio Pistis Lorna M Lopez Toomas Haller Perttu Salo Anuj Goel Man Li Toshiko Tanaka Abbas Dehghan Daniela Ruggiero Giovanni Malerba Albert V Smith Ilja M Nolte Laura Portas Amanda Phipps-Green Lora Boteva Pau Navarro Asa Johansson Andrew A Hicks Ozren Polasek Tõnu Esko John F Peden Sarah E Harris Federico Murgia Sarah H Wild Albert Tenesa Adrienne Tin Evelin Mihailov Anne Grotevendt Gauti K Gislason Josef Coresh Pio D'Adamo Sheila Ulivi Peter Vollenweider Gerard Waeber Susan Campbell Ivana Kolcic Krista Fisher Margus Viigimaa Jeffrey E Metter Corrado Masciullo Elisabetta Trabetti Cristina Bombieri Rossella Sorice Angela Döring Eva Reischl Konstantin Strauch Albert Hofman Andre G Uitterlinden Melanie Waldenberger H-Erich Wichmann Gail Davies Alan J Gow Nicola Dalbeth Lisa Stamp Johannes H Smit Mirna Kirin Ramaiah Nagaraja Matthias Nauck Claudia Schurmann Kathrin Budde Susan M Farrington Evropi Theodoratou Antti Jula Veikko Salomaa Cinzia Sala Christian Hengstenberg Michel Burnier Reedik Mägi Norman Klopp Stefan Kloiber Sabine Schipf Samuli Ripatti Stefano Cabras Nicole Soranzo Georg Homuth Teresa Nutile Patricia B Munroe Nicholas Hastie Harry Campbell Igor Rudan Claudia Cabrera Chris Haley Oscar H Franco Tony R Merriman Vilmundur Gudnason Mario Pirastu Brenda W Penninx Harold Snieder Andres Metspalu Marina Ciullo Peter P Pramstaller Cornelia M van Duijn Luigi Ferrucci Giovanni Gambaro Ian J Deary Malcolm G Dunlop James F Wilson Paolo Gasparini Ulf Gyllensten Tim D Spector Alan F Wright Caroline Hayward Hugh Watkins Markus Perola Murielle Bochud W H Linda Kao Mark Caulfield Daniela Toniolo Henry Völzke Christian Gieger Anna Köttgen Veronique Vitart

PLoS One 2015 26;10(3):e0119752. Epub 2015 Mar 26.

Medical Research Council (MRC) Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Edinburgh, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0119752PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374966PMC
March 2016

Erratum to: Genetic determination of height-mediated mate choice.

Genome Biol 2016 Feb 11;17:26. Epub 2016 Feb 11.

The Roslin Institute, The University of Edinburgh, Easter Bush Campus, Midlothian, EH25 9RG, Scotland, UK.

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http://dx.doi.org/10.1186/s13059-016-0894-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751647PMC
February 2016

Genetic determination of height-mediated mate choice.

Genome Biol 2016 Jan 19;16:269. Epub 2016 Jan 19.

The Roslin Institute, The University of Edinburgh, Easter Bush Campus, Midlothian, EH25 9RG, Scotland, UK.

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http://dx.doi.org/10.1186/s13059-015-0833-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717574PMC
January 2016

The Nature of Genetic Variation for Complex Traits Revealed by GWAS and Regional Heritability Mapping Analyses.

Genetics 2015 Dec 19;201(4):1601-13. Epub 2015 Oct 19.

Institute of Evolutionary Biology, University of Edinburgh, Edinburgh EH9 3FL, Scotland, United Kingdom.

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http://dx.doi.org/10.1534/genetics.115.177220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676519PMC
December 2015

Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

Authors:
Timothy H T Cheng Deborah Thompson Jodie Painter Tracy O'Mara Maggie Gorman Lynn Martin Claire Palles Angela Jones Daniel D Buchanan Aung Ko Win John Hopper Mark Jenkins Noralane M Lindor Polly A Newcomb Steve Gallinger David Conti Fred Schumacher Graham Casey Graham G Giles Paul Pharoah Julian Peto Angela Cox Anthony Swerdlow Fergus Couch Julie M Cunningham Ellen L Goode Stacey J Winham Diether Lambrechts Peter Fasching Barbara Burwinkel Hermann Brenner Hiltrud Brauch Jenny Chang-Claude Helga B Salvesen Vessela Kristensen Hatef Darabi Jingmei Li Tao Liu Annika Lindblom Per Hall Magdalena Echeverry de Polanco Monica Sans Angel Carracedo Sergi Castellvi-Bel Augusto Rojas-Martinez Samuel Aguiar Jnr Manuel R Teixeira Alison M Dunning Joe Dennis Geoffrey Otton Tony Proietto Elizabeth Holliday John Attia Katie Ashton Rodney J Scott Mark McEvoy Sean C Dowdy Brooke L Fridley Henrica M J Werner Jone Trovik Tormund S Njolstad Emma Tham Miriam Mints Ingo Runnebaum Peter Hillemanns Thilo Dörk Frederic Amant Stefanie Schrauwen Alexander Hein Matthias W Beckmann Arif Ekici Kamila Czene Alfons Meindl Manjeet K Bolla Kyriaki Michailidou Jonathan P Tyrer Qin Wang Shahana Ahmed Catherine S Healey Mitul Shah Daniela Annibali Jeroen Depreeuw Nada A Al-Tassan Rebecca Harris Brian F Meyer Nicola Whiffin Fay J Hosking Ben Kinnersley Susan M Farrington Maria Timofeeva Albert Tenesa Harry Campbell Robert W Haile Shirley Hodgson Luis Carvajal-Carmona Jeremy P Cheadle Douglas Easton Malcolm Dunlop Richard Houlston Amanda Spurdle Ian Tomlinson

Sci Rep 2015 12 1;5:17369. Epub 2015 Dec 1.

Molecular and Population Genetics Laboratory, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1038/srep17369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664893PMC
December 2015

A new tool called DISSECT for analysing large genomic data sets using a Big Data approach.

Nat Commun 2015 Dec 11;6:10162. Epub 2015 Dec 11.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush Campus, Edinburgh EH25 9RG, UK.

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http://dx.doi.org/10.1038/ncomms10162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682108PMC
December 2015

Evaluation of the linkage-disequilibrium method for the estimation of effective population size when generations overlap: an empirical case.

BMC Genomics 2015 Nov 11;16:922. Epub 2015 Nov 11.

Departamento de Mejora Genética Animal, INIA, Carretera de la Coruña km 7.5, 28040, Madrid, Spain.

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http://dx.doi.org/10.1186/s12864-015-2167-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642667PMC
November 2015

Genetic ancestry is associated with colorectal adenomas and adenocarcinomas in Latino populations.

Eur J Hum Genet 2014 Oct 12;22(10):1208-16. Epub 2014 Feb 12.

1] The Roslin Institute, The University of Edinburgh, Edinburgh, UK [2] MRC-Human Genetics Unit at the MRC IGMM, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1038/ejhg.2013.310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169534PMC
October 2014

Complex variation in measures of general intelligence and cognitive change.

PLoS One 2013 12;8(12):e81189. Epub 2013 Dec 12.

The Roslin Institute, The University of Edinburgh, Roslin, Scotland, United Kingdom ; Medical Research Council Human Genetics Unit at the Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0081189PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865348PMC
September 2014

Plasma vitamin D concentration influences survival outcome after a diagnosis of colorectal cancer.

J Clin Oncol 2014 Aug 7;32(23):2430-9. Epub 2014 Jul 7.

Lina Zgaga, Susan M. Farrington, Farhat V.N. Din, Li Yin Ooi, Dominik Glodzik, Albert Tenesa, Harry Campbell, and Malcolm G. Dunlop, University of Edinburgh and Western General Hospital; Evropi Theodoratou and Harry Campbell, University of Edinburgh, Edinburgh; Albert Tenesa, University of Edinburgh, Roslin; Susan Johnston, Glasgow Royal Infirmary, Glasgow, United Kingdom; Lina Zgaga, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1200/JCO.2013.54.5947DOI Listing
August 2014

Associations between dietary and lifestyle risk factors and colorectal cancer in the Scottish population.

Eur J Cancer Prev 2014 Jan;23(1):8-17

aDepartment of Environmental and Occupational Medicine, Liberty Safe Work Research Centre, University of Aberdeen, Aberdeen bCentre for Population Health Sciences, College of Medicine and Veterinary Medicine cColon Cancer Genetics Group, Institute of Genetics and Molecular Medicine dSchool of Informatics, College of Science and Engineering, University of Edinburgh eSchool of Nursing, Midwifery & Social Care, Faculty of Health, Life and Social Sciences, Edinburgh Napier University fSouth East Scotland Genetic Service, Western General Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1097/CEJ.0b013e3283639fb8DOI Listing
January 2014

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.

Authors:
Anna Köttgen Eva Albrecht Alexander Teumer Veronique Vitart Jan Krumsiek Claudia Hundertmark Giorgio Pistis Daniela Ruggiero Conall M O'Seaghdha Toomas Haller Qiong Yang Toshiko Tanaka Andrew D Johnson Zoltán Kutalik Albert V Smith Julia Shi Maksim Struchalin Rita P S Middelberg Morris J Brown Angelo L Gaffo Nicola Pirastu Guo Li Caroline Hayward Tatijana Zemunik Jennifer Huffman Loic Yengo Jing Hua Zhao Ayse Demirkan Mary F Feitosa Xuan Liu Giovanni Malerba Lorna M Lopez Pim van der Harst Xinzhong Li Marcus E Kleber Andrew A Hicks Ilja M Nolte Asa Johansson Federico Murgia Sarah H Wild Stephan J L Bakker John F Peden Abbas Dehghan Maristella Steri Albert Tenesa Vasiliki Lagou Perttu Salo Massimo Mangino Lynda M Rose Terho Lehtimäki Owen M Woodward Yukinori Okada Adrienne Tin Christian Müller Christopher Oldmeadow Margus Putku Darina Czamara Peter Kraft Laura Frogheri Gian Andri Thun Anne Grotevendt Gauti Kjartan Gislason Tamara B Harris Lenore J Launer Patrick McArdle Alan R Shuldiner Eric Boerwinkle Josef Coresh Helena Schmidt Michael Schallert Nicholas G Martin Grant W Montgomery Michiaki Kubo Yusuke Nakamura Toshihiro Tanaka Patricia B Munroe Nilesh J Samani David R Jacobs Kiang Liu Pio D'Adamo Sheila Ulivi Jerome I Rotter Bruce M Psaty Peter Vollenweider Gerard Waeber Susan Campbell Olivier Devuyst Pau Navarro Ivana Kolcic Nicholas Hastie Beverley Balkau Philippe Froguel Tõnu Esko Andres Salumets Kay Tee Khaw Claudia Langenberg Nicholas J Wareham Aaron Isaacs Aldi Kraja Qunyuan Zhang Philipp S Wild Rodney J Scott Elizabeth G Holliday Elin Org Margus Viigimaa Stefania Bandinelli Jeffrey E Metter Antonio Lupo Elisabetta Trabetti Rossella Sorice Angela Döring Eva Lattka Konstantin Strauch Fabian Theis Melanie Waldenberger H-Erich Wichmann Gail Davies Alan J Gow Marcel Bruinenberg Ronald P Stolk Jaspal S Kooner Weihua Zhang Bernhard R Winkelmann Bernhard O Boehm Susanne Lucae Brenda W Penninx Johannes H Smit Gary Curhan Poorva Mudgal Robert M Plenge Laura Portas Ivana Persico Mirna Kirin James F Wilson Irene Mateo Leach Wiek H van Gilst Anuj Goel Halit Ongen Albert Hofman Fernando Rivadeneira Andre G Uitterlinden Medea Imboden Arnold von Eckardstein Francesco Cucca Ramaiah Nagaraja Maria Grazia Piras Matthias Nauck Claudia Schurmann Kathrin Budde Florian Ernst Susan M Farrington Evropi Theodoratou Inga Prokopenko Michael Stumvoll Antti Jula Markus Perola Veikko Salomaa So-Youn Shin Tim D Spector Cinzia Sala Paul M Ridker Mika Kähönen Jorma Viikari Christian Hengstenberg Christopher P Nelson James F Meschia Michael A Nalls Pankaj Sharma Andrew B Singleton Naoyuki Kamatani Tanja Zeller Michel Burnier John Attia Maris Laan Norman Klopp Hans L Hillege Stefan Kloiber Hyon Choi Mario Pirastu Silvia Tore Nicole M Probst-Hensch Henry Völzke Vilmundur Gudnason Afshin Parsa Reinhold Schmidt John B Whitfield Myriam Fornage Paolo Gasparini David S Siscovick Ozren Polašek Harry Campbell Igor Rudan Nabila Bouatia-Naji Andres Metspalu Ruth J F Loos Cornelia M van Duijn Ingrid B Borecki Luigi Ferrucci Giovanni Gambaro Ian J Deary Bruce H R Wolffenbuttel John C Chambers Winfried März Peter P Pramstaller Harold Snieder Ulf Gyllensten Alan F Wright Gerjan Navis Hugh Watkins Jacqueline C M Witteman Serena Sanna Sabine Schipf Malcolm G Dunlop Anke Tönjes Samuli Ripatti Nicole Soranzo Daniela Toniolo Daniel I Chasman Olli Raitakari W H Linda Kao Marina Ciullo Caroline S Fox Mark Caulfield Murielle Bochud Christian Gieger

Nat Genet 2013 Feb 23;45(2):145-54. Epub 2012 Dec 23.

Renal Division, Freiburg University Hospital, Freiburg, Germany.

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http://dx.doi.org/10.1038/ng.2500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663712PMC
February 2013

The heritability of human disease: estimation, uses and abuses.

Nat Rev Genet 2013 Feb;14(2):139-49

Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.

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http://search.proquest.com/openview/59a69216a021c22cbd3d64e9
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http://dx.doi.org/10.1038/nrg3377DOI Listing
February 2013

Evidence of inbreeding depression on human height.

PLoS Genet 2012 19;8(7):e1002655. Epub 2012 Jul 19.

Centre for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1002655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400549PMC
January 2013

The role of ECE1 variants in cognitive ability in old age and Alzheimer's disease risk.

Am J Med Genet B Neuropsychiatr Genet 2012 Sep 12;159B(6):696-709. Epub 2012 Jun 12.

Medical Genetics, Molecular Medicine Centre, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1002/ajmg.b.32073DOI Listing
September 2012

Human complex trait genetics: lifting the lid of the genomics toolbox - from pathways to prediction.

Curr Genomics 2012 May;13(3):213-24

The Roslin Institute, The University of Edinburgh, Easter Bush Campus, Midlothian, EH25 9RG, Scotland, UK.

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http://dx.doi.org/10.2174/138920212800543101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382276PMC
May 2012

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.

Authors:
Lisette Stolk John R B Perry Daniel I Chasman Chunyan He Massimo Mangino Patrick Sulem Maja Barbalic Linda Broer Enda M Byrne Florian Ernst Tõnu Esko Nora Franceschini Daniel F Gudbjartsson Jouke-Jan Hottenga Peter Kraft Patrick F McArdle Eleonora Porcu So-Youn Shin Albert V Smith Sophie van Wingerden Guangju Zhai Wei V Zhuang Eva Albrecht Behrooz Z Alizadeh Thor Aspelund Stefania Bandinelli Lovorka Barac Lauc Jacques S Beckmann Mladen Boban Eric Boerwinkle Frank J Broekmans Andrea Burri Harry Campbell Stephen J Chanock Constance Chen Marilyn C Cornelis Tanguy Corre Andrea D Coviello Pio d'Adamo Gail Davies Ulf de Faire Eco J C de Geus Ian J Deary George V Z Dedoussis Panagiotis Deloukas Shah Ebrahim Gudny Eiriksdottir Valur Emilsson Johan G Eriksson Bart C J M Fauser Liana Ferreli Luigi Ferrucci Krista Fischer Aaron R Folsom Melissa E Garcia Paolo Gasparini Christian Gieger Nicole Glazer Diederick E Grobbee Per Hall Toomas Haller Susan E Hankinson Merli Hass Caroline Hayward Andrew C Heath Albert Hofman Erik Ingelsson A Cecile J W Janssens Andrew D Johnson David Karasik Sharon L R Kardia Jules Keyzer Douglas P Kiel Ivana Kolcic Zoltán Kutalik Jari Lahti Sandra Lai Triin Laisk Joop S E Laven Debbie A Lawlor Jianjun Liu Lorna M Lopez Yvonne V Louwers Patrik K E Magnusson Mara Marongiu Nicholas G Martin Irena Martinovic Klaric Corrado Masciullo Barbara McKnight Sarah E Medland David Melzer Vincent Mooser Pau Navarro Anne B Newman Dale R Nyholt N Charlotte Onland-Moret Aarno Palotie Guillaume Paré Alex N Parker Nancy L Pedersen Petra H M Peeters Giorgio Pistis Andrew S Plump Ozren Polasek Victor J M Pop Bruce M Psaty Katri Räikkönen Emil Rehnberg Jerome I Rotter Igor Rudan Cinzia Sala Andres Salumets Angelo Scuteri Andrew Singleton Jennifer A Smith Harold Snieder Nicole Soranzo Simon N Stacey John M Starr Maria G Stathopoulou Kathleen Stirrups Ronald P Stolk Unnur Styrkarsdottir Yan V Sun Albert Tenesa Barbara Thorand Daniela Toniolo Laufey Tryggvadottir Kim Tsui Sheila Ulivi Rob M van Dam Yvonne T van der Schouw Carla H van Gils Peter van Nierop Jacqueline M Vink Peter M Visscher Marlies Voorhuis Gérard Waeber Henri Wallaschofski H Erich Wichmann Elisabeth Widen Colette J M Wijnands-van Gent Gonneke Willemsen James F Wilson Bruce H R Wolffenbuttel Alan F Wright Laura M Yerges-Armstrong Tatijana Zemunik Lina Zgaga M Carola Zillikens Marek Zygmunt Alice M Arnold Dorret I Boomsma Julie E Buring Laura Crisponi Ellen W Demerath Vilmundur Gudnason Tamara B Harris Frank B Hu David J Hunter Lenore J Launer Andres Metspalu Grant W Montgomery Ben A Oostra Paul M Ridker Serena Sanna David Schlessinger Tim D Spector Kari Stefansson Elizabeth A Streeten Unnur Thorsteinsdottir Manuela Uda André G Uitterlinden Cornelia M van Duijn Henry Völzke Anna Murray Joanne M Murabito Jenny A Visser Kathryn L Lunetta

Nat Genet 2012 Jan 22;44(3):260-8. Epub 2012 Jan 22.

Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/ng.1051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288642PMC
January 2012

Alzheimer's disease genes are associated with measures of cognitive ageing in the lothian birth cohorts of 1921 and 1936.

Int J Alzheimers Dis 2011 12;2011:505984. Epub 2011 Jun 12.

Medical Genetics, Molecular Medicine Centre, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.4061/2011/505984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132531PMC
November 2011

New gene functions in megakaryopoiesis and platelet formation.

Authors:
Christian Gieger Aparna Radhakrishnan Ana Cvejic Weihong Tang Eleonora Porcu Giorgio Pistis Jovana Serbanovic-Canic Ulrich Elling Alison H Goodall Yann Labrune Lorna M Lopez Reedik Mägi Stuart Meacham Yukinori Okada Nicola Pirastu Rossella Sorice Alexander Teumer Katrin Voss Weihua Zhang Ramiro Ramirez-Solis Joshua C Bis David Ellinghaus Martin Gögele Jouke-Jan Hottenga Claudia Langenberg Peter Kovacs Paul F O'Reilly So-Youn Shin Tõnu Esko Jaana Hartiala Stavroula Kanoni Federico Murgia Afshin Parsa Jonathan Stephens Pim van der Harst C Ellen van der Schoot Hooman Allayee Antony Attwood Beverley Balkau François Bastardot Saonli Basu Sebastian E Baumeister Ginevra Biino Lorenzo Bomba Amélie Bonnefond François Cambien John C Chambers Francesco Cucca Pio D'Adamo Gail Davies Rudolf A de Boer Eco J C de Geus Angela Döring Paul Elliott Jeanette Erdmann David M Evans Mario Falchi Wei Feng Aaron R Folsom Ian H Frazer Quince D Gibson Nicole L Glazer Chris Hammond Anna-Liisa Hartikainen Susan R Heckbert Christian Hengstenberg Micha Hersch Thomas Illig Ruth J F Loos Jennifer Jolley Kay Tee Khaw Brigitte Kühnel Marie-Christine Kyrtsonis Vasiliki Lagou Heather Lloyd-Jones Thomas Lumley Massimo Mangino Andrea Maschio Irene Mateo Leach Barbara McKnight Yasin Memari Braxton D Mitchell Grant W Montgomery Yusuke Nakamura Matthias Nauck Gerjan Navis Ute Nöthlings Ilja M Nolte David J Porteous Anneli Pouta Peter P Pramstaller Janne Pullat Susan M Ring Jerome I Rotter Daniela Ruggiero Aimo Ruokonen Cinzia Sala Nilesh J Samani Jennifer Sambrook David Schlessinger Stefan Schreiber Heribert Schunkert James Scott Nicholas L Smith Harold Snieder John M Starr Michael Stumvoll Atsushi Takahashi W H Wilson Tang Kent Taylor Albert Tenesa Swee Lay Thein Anke Tönjes Manuela Uda Sheila Ulivi Dirk J van Veldhuisen Peter M Visscher Uwe Völker H-Erich Wichmann Kerri L Wiggins Gonneke Willemsen Tsun-Po Yang Jing Hua Zhao Paavo Zitting John R Bradley George V Dedoussis Paolo Gasparini Stanley L Hazen Andres Metspalu Mario Pirastu Alan R Shuldiner L Joost van Pelt Jaap-Jan Zwaginga Dorret I Boomsma Ian J Deary Andre Franke Philippe Froguel Santhi K Ganesh Marjo-Riitta Jarvelin Nicholas G Martin Christa Meisinger Bruce M Psaty Timothy D Spector Nicholas J Wareham Jan-Willem N Akkerman Marina Ciullo Panos Deloukas Andreas Greinacher Steve Jupe Naoyuki Kamatani Jyoti Khadake Jaspal S Kooner Josef Penninger Inga Prokopenko Derek Stemple Daniela Toniolo Lorenz Wernisch Serena Sanna Andrew A Hicks Augusto Rendon Manuel A Ferreira Willem H Ouwehand Nicole Soranzo

Nature 2011 Nov 30;480(7376):201-8. Epub 2011 Nov 30.

Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr 1, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1038/nature10659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335296PMC
November 2011

Effect of aspirin and NSAIDs on risk and survival from colorectal cancer.

Gut 2010 Dec 15;59(12):1670-9. Epub 2010 Sep 15.

Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, University of Edinburgh and MRC Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1136/gut.2009.203000DOI Listing
December 2010

Ten common genetic variants associated with colorectal cancer risk are not associated with survival after diagnosis.

Clin Cancer Res 2010 Jul 13;16(14):3754-9. Epub 2010 Jul 13.

Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, Western General Hospital Edinburgh, University of Edinburgh and MRC Human Genetics Unit, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-0439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906703PMC
July 2010

Common variants of large effect in F12, KNG1, and HRG are associated with activated partial thromboplastin time.

Am J Hum Genet 2010 Apr 18;86(4):626-31. Epub 2010 Mar 18.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, The University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK.

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http://dx.doi.org/10.1016/j.ajhg.2010.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850435PMC
April 2010

Association between common mtDNA variants and all-cause or colorectal cancer mortality.

Carcinogenesis 2010 Feb 27;31(2):296-301. Epub 2009 Nov 27.

Public Health Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1093/carcin/bgp237DOI Listing
February 2010

New insights into the aetiology of colorectal cancer from genome-wide association studies.

Nat Rev Genet 2009 Jun;10(6):353-8

Colon Cancer Genetics Group, University of Edinburgh, Western General Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1038/nrg2574DOI Listing
June 2009

Modification of the associations between lifestyle, dietary factors and colorectal cancer risk by APC variants.

Carcinogenesis 2008 Sep 28;29(9):1774-80. Epub 2008 Mar 28.

Public Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.

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http://dx.doi.org/10.1093/carcin/bgn082DOI Listing
September 2008

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.

Nat Genet 2008 May 30;40(5):623-30. Epub 2008 Mar 30.

Molecular and Population Genetics Laboratory, London Research Institute, Cancer Research UK, London WC2A 3PX, UK.

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http://dx.doi.org/10.1038/ng.111DOI Listing
May 2008

Dietary vitamin B6 intake and the risk of colorectal cancer.

Cancer Epidemiol Biomarkers Prev 2008 Jan;17(1):171-82

Public Health Sciences, College of Medicine and Vet Medicine, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-07-0621DOI Listing
January 2008

Dietary fatty acids and colorectal cancer: a case-control study.

Am J Epidemiol 2007 Jul 9;166(2):181-95. Epub 2007 May 9.

Public Health Sciences, University of Edinburgh, Edinburgh, United Kingdom.

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https://academic.oup.com/aje/article-lookup/doi/10.1093/aje/
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http://dx.doi.org/10.1093/aje/kwm063DOI Listing
July 2007

Recent human effective population size estimated from linkage disequilibrium.

Genome Res 2007 Apr 9;17(4):520-6. Epub 2007 Mar 9.

Colon Cancer Genetics Group, University of Edinburgh, Western General Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1101/gr.6023607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1832099PMC
April 2007

Dietary flavonoids and the risk of colorectal cancer.

Cancer Epidemiol Biomarkers Prev 2007 Apr;16(4):684-93

Public Health Sciences, College of Medicine and Vet Medicine, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-06-0785DOI Listing
April 2007

Identification and survival of carriers of mutations in DNA mismatch-repair genes in colon cancer.

N Engl J Med 2006 Jun;354(26):2751-63

Colon Cancer Genetics Group, School of Molecular and Clinical Medicine, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1056/NEJMoa053493DOI Listing
June 2006

Validity of tagging SNPs across populations for association studies.

Eur J Hum Genet 2006 Mar;14(3):357-63

Colon Cancer Genetics Group, University of Edinburgh, School of Molecular and Clinical Medicine, Western General Hospital, Crewe Road, Edinburgh, UK.

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http://dx.doi.org/10.1038/sj.ejhg.5201554DOI Listing
March 2006

Association of DLG5 and inflammatory bowel disease across populations.

Eur J Hum Genet 2006 Mar;14(3):259-60; author reply 260-1

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http://dx.doi.org/10.1038/sj.ejhg.5201516DOI Listing
March 2006

The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn's disease.

Gastroenterology 2005 Dec;129(6):1854-64

Gastrointestinal Unit, Western General Hospital, University of Edinburgh, Edinburgh, Scotland.

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http://dx.doi.org/10.1053/j.gastro.2005.09.025DOI Listing
December 2005

Germline susceptibility to colorectal cancer due to base-excision repair gene defects.

Am J Hum Genet 2005 Jul 3;77(1):112-9. Epub 2005 May 3.

Colon Cancer Genetics Group, School of Clinical and Molecular Medicine, University of Edinburgh, United Kingdom.

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http://linkinghub.elsevier.com/retrieve/pii/S000292970760906
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http://dx.doi.org/10.1086/431213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1226182PMC
July 2005

Mapping quantitative trait loci using linkage disequilibrium: marker- versus trait-based methods.

Behav Genet 2005 Mar;35(2):219-28

School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland, EH9 3JT, UK.

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http://dx.doi.org/10.1007/s10519-004-0811-5DOI Listing
March 2005

Allelic variations of the multidrug resistance gene determine susceptibility and disease behavior in ulcerative colitis.

Gastroenterology 2005 Feb;128(2):288-96

Gastrointestinal Unit, Western General Hospital, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1053/j.gastro.2004.11.019DOI Listing
February 2005