Publications by authors named "Albert E Chudley"

82Publications

Profile of Mothers of Children with Fetal Alcohol Spectrum Disorder: A Population-Based Study in Canada.

Int J Environ Res Public Health 2020 Oct 30;17(21). Epub 2020 Oct 30.

Centre for Addiction and Mental Health, Institute for Mental Health Policy Research, 33 Ursula Franklin Street, Toronto, ON M5S 2S1, Canada.

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http://dx.doi.org/10.3390/ijerph17217986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663482PMC
October 2020

Alternative genomic diagnoses for individuals with a clinical diagnosis of Dubowitz syndrome.

Am J Med Genet A 2020 Oct 24. Epub 2020 Oct 24.

Department of Medical Genetics and Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1002/ajmg.a.61926DOI Listing
October 2020

Population-based prevalence of fetal alcohol spectrum disorder in Canada.

BMC Public Health 2019 Jun 28;19(1):845. Epub 2019 Jun 28.

Centre for Addiction and Mental Health, Institute for Mental Health Policy Research, 33 Russell Street, Toronto, ON, M5S 2S1, Canada.

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http://dx.doi.org/10.1186/s12889-019-7213-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599312PMC
June 2019

Kabuki syndrome: international consensus diagnostic criteria.

J Med Genet 2019 02 4;56(2):89-95. Epub 2018 Dec 4.

President, the Research Institute of Personalized Health Sciences, Health Sciences University of Hokkaido, Hokkaido, Japan.

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http://dx.doi.org/10.1136/jmedgenet-2018-105625DOI Listing
February 2019

A global research collaboration on fetal alcohol spectrum disorder.

Biochem Cell Biol 2018 04 10;96(2):vii-viii. Epub 2018 Apr 10.

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http://dx.doi.org/10.1139/bcb-2018-0088DOI Listing
April 2018

Copy number variation in fetal alcohol spectrum disorder.

Biochem Cell Biol 2018 04 13;96(2):161-166. Epub 2018 Mar 13.

a The Centre for Applied Genomics and Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON M5G 04A, Canada.

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http://dx.doi.org/10.1139/bcb-2017-0241DOI Listing
April 2018

DNA methylation as a predictor of fetal alcohol spectrum disorder.

Clin Epigenetics 2018 12;10. Epub 2018 Jan 12.

1Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, British Columbia Children's Hospital Research Institute, University of British Columbia, Vancouver, British Columbia Canada.

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http://dx.doi.org/10.1186/s13148-018-0439-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767049PMC
February 2019

Human Brain Abnormalities Associated With Prenatal Alcohol Exposure and Fetal Alcohol Spectrum Disorder.

J Neuropathol Exp Neurol 2017 Sep;76(9):813-833

Department of Human Anatomy and Cell Science, University of Manitoba, Winnipeg, Manitoba, Canada; Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada; Department of Pathology, University of Manitoba, Winnipeg, Manitoba; and Department of Paediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada; and Diagnostic Services Manitoba, Winnipeg, Manitoba, Canada.

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https://academic.oup.com/jnen/article/76/9/813/4079677
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http://dx.doi.org/10.1093/jnen/nlx064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901082PMC
September 2017

Fetal Alcohol Spectrum Disorder-High Rates, High Needs, High Time for Action.

Authors:
Albert E Chudley

JAMA Pediatr 2017 10;171(10):940-941

Department of Pediatrics and Child Health, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.

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http://dx.doi.org/10.1001/jamapediatrics.2017.2232DOI Listing
October 2017

Diagnosis of fetal alcohol spectrum disorder: current practices and future considerations.

Authors:
Albert E Chudley

Biochem Cell Biol 2018 04 26;96(2):231-236. Epub 2017 Jul 26.

Department of Pediatrics and Child Health and Department of Biochemistry and Medical Genetics, Max Rady College of Medicine, Rady Faculty of Heath Sciences, University of Manitoba, and the Children's Hospital, Winnipeg, MB R3A 1R9, Canada.

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http://dx.doi.org/10.1139/bcb-2017-0106DOI Listing
April 2018

DNA methylation signature of human fetal alcohol spectrum disorder.

Epigenetics Chromatin 2016 29;9:25. Epub 2016 Jun 29.

Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, BC Canada.

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http://dx.doi.org/10.1186/s13072-016-0074-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926300PMC
June 2016

Overview of the Genetic Basis and Epigenetic Mechanisms that Contribute to FASD Pathobiology.

Curr Top Med Chem 2017 ;17(7):808-828

Department of Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, University of Manitoba, 745 Bannatyne Avenue, Winnipeg, Manitoba, R3E 0J9, Canada.

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http://dx.doi.org/10.2174/1568026616666160414124816DOI Listing
February 2017

Comorbidity of fetal alcohol spectrum disorder: a systematic review and meta-analysis.

Lancet 2016 Mar 6;387(10022):978-987. Epub 2016 Jan 6.

Social and Epidemiological Research Department, Centre for Addiction and Mental Health, Toronto, ON, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada; Institute of Medical Science, University of Toronto, Toronto, ON, Canada; Epidemiological Research Unit, Klinische Psychologie and Psychotherapie, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1016/S0140-6736(15)01345-8DOI Listing
March 2016

Fetal alcohol spectrum disorder: a guideline for diagnosis across the lifespan.

CMAJ 2016 Feb 14;188(3):191-197. Epub 2015 Dec 14.

Canada Fetal Alcohol Spectrum Disorder Research Network (Cook, Green, Lutke); Society of Obstetricians and Gynaecologists of Canada (Cook, Green), Ottawa, Ont.; Department of Obstetrics and Gynaecology (Cook), University of Ottawa, Ottawa, Ont.; Department of Biomedical and Molecular Sciences (Green), Queen's University, Kingston, Ont.; Sunny Hill Health Centre for Children (Lilley), Vancouver, BC; National Institutes of Health (Anderson), Ottawa, Ont.; Fetal Alcohol Spectrum Disorders Clinic (Baldwin), Child Development Services, Alberta Children's Hospital, Calgary, Alta.; Department of Pediatrics (Chudley), University of Manitoba, Winnipeg, Man.; University of British Columbia (Conry [professor emerita]), Vancouver, BC; Department of Pediatrics (LeBlanc), Dr. Georges-L.-Dumont University Hospital Centre, Université de Moncton and Université de Sherbrooke, Moncton, NB; Department of Pediatrics (Looke), University of British Columbia, Vancouver, BC; Glenrose Rehabilitation Hospital (Mallon), Alberta Health Services, Edmonton, Alta.; Lakeland Centre for Fetal Alcohol Syndrome (McFarlane), Cold Lake, Alta.; Surrey Place Centre (Temple), Toronto, Ont.; Faculty of Medicine (Rosales), Memorial University of Newfoundland, St. John's, Nfld.

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http://dx.doi.org/10.1503/cmaj.141593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754181PMC
February 2016

An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes.

Nat Cell Biol 2015 Aug 13;17(8):1074-1087. Epub 2015 Jul 13.

Section of Ophthalmology and Neuroscience, Leeds Institutes of Molecular Medicine, University of Leeds, Leeds, LS9 7TF, UK.

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http://www.nature.com/articles/ncb3201
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http://dx.doi.org/10.1038/ncb3201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536769PMC
August 2015

Response to correspondence on "lissencephaly with brainstem and cerebellar hypoplasia and congenital cataracts".

J Child Neurol 2015 Apr;30(5):666

Children's Hospital, University of Manitoba, Winnipeg, Manitoba, Canada.

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http://dx.doi.org/10.1177/0883073813494478DOI Listing
April 2015

Visual search for feature conjunctions: an fMRI study comparing alcohol-related neurodevelopmental disorder (ARND) to ADHD.

J Neurodev Disord 2015 4;7(1):10. Epub 2015 Mar 4.

Department of Pediatrics and Child Health, CE-203 Children's Hospital, Health Sciences Centre, 840 Sherbrook Street, Winnipeg, MB R3A 1S1 Canada.

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http://dx.doi.org/10.1186/s11689-015-9106-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351830PMC
March 2015

A case of an infant with compound heterozygous mutations for hypertrophic cardiomyopathy producing a phenotype of left ventricular noncompaction.

Can J Cardiol 2014 Oct 12;30(10):1249.e1-3. Epub 2014 Jun 12.

Department of Laboratory Medicine and Pathology, University of Alberta, and Stollery Children's Hospital, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1016/j.cjca.2014.05.021DOI Listing
October 2014

Copy number variants (CNVs) analysis in a deeply phenotyped cohort of individuals with intellectual disability (ID).

BMC Med Genet 2014 Jul 16;15:82. Epub 2014 Jul 16.

Department of Pathology (Cytogenetics), BC Child and Family Research Institute, University of British Columbia (UBC), 950 West 28th, Room 3060, Vancouver, BC V5Z 4H4, Canada.

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http://dx.doi.org/10.1186/1471-2350-15-82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107469PMC
July 2014

The differential diagnosis of fetal alcohol spectrum disorder.

J Popul Ther Clin Pharmacol 2014 10;21(1):e1-e30. Epub 2014 Feb 10.

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July 2015

Radiographic characterization of the hands in Ritscher-Schinzel/3-C syndrome.

Springerplus 2013 7;2:594. Epub 2013 Nov 7.

Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba R3E 0W3 Canada.

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http://dx.doi.org/10.1186/2193-1801-2-594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830001PMC
November 2013

Use of health, education, and social services by individuals with fetal alcohol spectrum disorder.

J Popul Ther Clin Pharmacol 2013 26;20(2):e95-e106. Epub 2013 Apr 26.

Department of Community Health Sciences-Manitoba Centre for Health Policy, Faculty of Medicine, University of Manitoba, Canada.

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December 2013

Lissencephaly with brainstem and cerebellar hypoplasia and congenital cataracts.

J Child Neurol 2014 Jun 26;29(6):860-4. Epub 2013 Apr 26.

Section of Pediatric Neurology, University of Manitoba, Winnipeg, MB, Canada Department of Pediatrics and Child Health, Children's Hospital, University of Manitoba, Winnipeg, MB, Canada

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http://dx.doi.org/10.1177/0883073813485637DOI Listing
June 2014

Cost of fetal alcohol spectrum disorder diagnosis in Canada.

PLoS One 2013 4;8(4):e60434. Epub 2013 Apr 4.

Social and Epidemiological Research Department, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0060434PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617033PMC
November 2013

The Coffin-Siris syndrome: a proposed diagnostic approach and assessment of 15 overlapping cases.

Am J Med Genet A 2012 Aug 18;158A(8):1865-76. Epub 2012 Jun 18.

Division of Human Genetics, The Children's Hospital of Philadelphia, and Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1002/ajmg.a.35415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402612PMC
August 2012

A shared founder mutation underlies restrictive dermopathy in Old Colony (Dutch-German) Mennonite and Hutterite patients in North America.

Am J Med Genet A 2012 May 11;158A(5):1229-32. Epub 2012 Apr 11.

Department of Medical Genetics, Alberta Children's Hospital and Alberta Children's Hospital Research Institute for Child and Maternal Health, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1002/ajmg.a.35302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247856PMC
May 2012

Risk factors for nonsyndromic holoprosencephaly: a Manitoba case-control study.

Am J Med Genet A 2012 Apr 14;158A(4):751-8. Epub 2012 Mar 14.

Department of Pediatrics, William Osler Health System, Brampton, Ontario, Canada.

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http://dx.doi.org/10.1002/ajmg.a.35240DOI Listing
April 2012

Trends in telehealth versus on-site clinical genetics appointments in Manitoba: a comparative study.

J Genet Couns 2012 Apr 15;21(2):337-44. Epub 2011 Oct 15.

WRHA Program of Genetics and Metabolism, University of Manitoba, Winnipeg, MB, Canada.

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http://dx.doi.org/10.1007/s10897-011-9406-5DOI Listing
April 2012

Research use of leftover newborn bloodspots: attitudes of Canadian geneticists regarding storage and informed consent requirements.

Genet Med 2011 Apr;13(4):305-13

Department of Genetics, Children's Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON, Canada.

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http://dx.doi.org/10.1097/GIM.0b013e3181f69da0DOI Listing
April 2011

Functional evaluation of hidden figures object analysis in children with autistic disorder.

J Autism Dev Disord 2011 Jan;41(1):13-22

National Research Council, Institute for Biodiagnostics, 435 Ellice Avenue, Winnipeg, MB, R3B 1Y6, Canada.

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http://dx.doi.org/10.1007/s10803-010-1013-zDOI Listing
January 2011

Normal distribution of palpebral fissure lengths in Canadian school age children.

Can J Clin Pharmacol 2010 10;17(1):e67-78. Epub 2010 Feb 10.

Canada Northwest FASD Research Network, Vancouver, Canada.

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April 2010

Concordance of three methods for palpebral fissure length measurement in the assessment of fetal alcohol spectrum disorder.

Can J Clin Pharmacol 2009 16;16(1):e234-41. Epub 2009 Apr 16.

Faculty of Medicine, University of Manitoba, Manitoba, Canada.

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June 2009

Increased nuchal translucency thickness: a potential indicator for Ritscher-Schinzel syndrome.

Fetal Diagn Ther 2008 28;24(4):395-9. Epub 2008 Oct 28.

Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Man., Canada.

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http://dx.doi.org/10.1159/000165697DOI Listing
April 2009

Routine genetic testing for Asperger syndrome.

Genet Med 2008 Nov;10(11):843-5; author reply 845

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http://dx.doi.org/10.1097/GIM.0b013e31818b0c76DOI Listing
November 2008

Development of Canadian screening tools for fetal alcohol spectrum disorder.

Can J Clin Pharmacol 2008 5;15(2):e344-66. Epub 2008 Sep 5.

The Motherisk Program, Division of Clinical Pharmacology & Toxicology, The Hospital for Sick Children, Toronto, Ontario.

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November 2008

The DLX1and DLX2 genes and susceptibility to autism spectrum disorders.

Eur J Hum Genet 2009 Feb 27;17(2):228-35. Epub 2008 Aug 27.

Department of Psychiatry, Queen's University, Kingston, Ontario, Canada.

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http://dx.doi.org/10.1038/ejhg.2008.148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2986060PMC
February 2009

Fetal alcohol spectrum disorder: counting the invisible - mission impossible?

Authors:
Albert E Chudley

Arch Dis Child 2008 Sep;93(9):721-2

University of Manitoba, Program in Genetics and Metabolism, Children's Hospital, FE 229, 840 Sherbrook Street, Winnipeg, Manitoba R3T 3W6, Canada.

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http://dx.doi.org/10.1136/adc.2008.137109DOI Listing
September 2008

Unique disease heritage of the Dutch-German Mennonite population.

Am J Med Genet A 2008 Apr;146A(8):1072-87

Department of Medical Genetics, Faculty of Medicine, Institute of Maternal and Child Health, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1002/ajmg.a.32061DOI Listing
April 2008

Challenges of diagnosis in fetal alcohol syndrome and fetal alcohol spectrum disorder in the adult.

Am J Med Genet C Semin Med Genet 2007 Aug;145C(3):261-72

Department of Pediatrics, University of Manitoba, Manitoba.

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http://dx.doi.org/10.1002/ajmg.c.30140DOI Listing
August 2007

Manitoba Oculotrichoanal (MOTA) syndrome: report of eight new cases.

Am J Med Genet A 2007 Apr;143A(8):853-7

Genetics and Metabolism Program, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada.

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http://doi.wiley.com/10.1002/ajmg.a.31446
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http://dx.doi.org/10.1002/ajmg.a.31446DOI Listing
April 2007

Clinical and epidemiological findings in patients with central ray deficiency: split hand foot malformation (SHFM) in Manitoba, Canada.

Am J Med Genet A 2006 Jul;140(13):1428-39

Department of Biochemistry and Medical Genetics, University of Manitoba, 770 Bannatyne Avenue, Winnipeg, Manitoba, Canada.

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http://dx.doi.org/10.1002/ajmg.a.31245DOI Listing
July 2006

The floppy infant: retrospective analysis of clinical experience (1990-2000) in a tertiary care facility.

J Child Neurol 2005 Oct;20(10):803-8

Section of Pediatric Neurosciences, Faculty of Medicine, University of Manitoba, Winnipeg, MB, Canada.

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http://dx.doi.org/10.1177/08830738050200100401DOI Listing
October 2005

Autosomal recessive cerebellar hypoplasia in the Hutterite population.

Dev Med Child Neurol 2005 Oct;47(10):691-5

Division of Neurology, Alberta Children's Hospital, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1017/S0012162205001404DOI Listing
October 2005

Identifying fetal alcohol spectrum disorder in primary care.

CMAJ 2005 Mar;172(5):628-30

Department of Pediatrics, University of British Columbia, Vancouver, BC.

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http://www.cmaj.ca/cgi/doi/10.1503/cmaj.050135
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http://dx.doi.org/10.1503/cmaj.050135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC550629PMC
March 2005

Fetal alcohol spectrum disorder: Canadian guidelines for diagnosis.

CMAJ 2005 Mar;172(5 Suppl):S1-S21

Children's Hospital, Health Sciences Centre, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Man.

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http://dx.doi.org/10.1503/cmaj.1040302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC557121PMC
March 2005

Cenani-Lenz syndactyly in a patient with features of Kabuki syndrome.

Clin Dysmorphol 2004 Jul;13(3):143-50

Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Canada.

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http://dx.doi.org/10.1097/01.mcd.0000127466.26888.15DOI Listing
July 2004

The duplicated longitudinal epiphysis or "kissing delta phalanx": evolution and variation in three different disorders.

Skeletal Radiol 2004 Jun 6;33(6):345-51. Epub 2004 May 6.

Department of Biochemistry and Medical Genetics, University of Manitoba, 770 Bannatyne Avenue, Winnipeg, Manitoba, R3E 0W3, Canada.

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http://link.springer.com/10.1007/s00256-004-0752-3
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http://dx.doi.org/10.1007/s00256-004-0752-3DOI Listing
June 2004

Severe hemihypotrophy in a female infant with mosaic Turner syndrome: a variant of Russell-Silver syndrome?

Clin Dysmorphol 2004 Apr;13(2):95-8

Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Canada.

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http://dx.doi.org/10.1097/00019605-200404000-00008DOI Listing
April 2004

Vascular anomalies in Alagille syndrome: a significant cause of morbidity and mortality.

Circulation 2004 Mar 1;109(11):1354-8. Epub 2004 Mar 1.

Division of Gastroenterology and Nutrition, The Children's Hospital of Philadelphia and The University of Pennsylvania School of Medicine, Philadelphia, Pa 19104, USA.

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http://dx.doi.org/10.1161/01.CIR.0000121361.01862.A4DOI Listing
March 2004

Fetal alcohol spectrum disorder.

CMAJ 2003 Nov;169(11):1181-5

Motherisk Program, Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children and University of Toronto, Toronto, Ont.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC264960PMC
November 2003

Solvent abuse in pregnancy: a perinatal perspective.

J Obstet Gynaecol Can 2002 Jan;24(1):22-6

Department of Obstetrics and Gynecology, University of Manitoba, Winnipeg, MB.

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http://dx.doi.org/10.1016/s1701-2163(16)30270-5DOI Listing
January 2002

A not-so-"new" mental retardation syndrome.

Am J Med Genet 2002 Jul;111(1):106; author reply 107-8

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http://dx.doi.org/10.1002/ajmg.10503DOI Listing
July 2002

Genetics and cardiac anomalies: the heart of the matter.

Indian J Pediatr 2002 Apr;69(4):321-32

Department of Pediatrics, Children's Hospital, Winnipeg, Canada.

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http://dx.doi.org/10.1007/BF02723219DOI Listing
April 2002