Alastair J Noyce

Alastair J Noyce

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Alastair J Noyce

Alastair J Noyce

Publications by authors named "Alastair J Noyce"

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Mendelian Randomization-A Journey From Obscurity to Center Stage With a Few Potholes Along the Way.

JAMA Neurol 2019 Oct 14. Epub 2019 Oct 14.

Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1001/jamaneurol.2019.3419DOI Listing
October 2019

The Parkinson's Disease Mendelian Randomization Research Portal.

Mov Disord 2019 Oct 28. Epub 2019 Oct 28.

Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1002/mds.27873DOI Listing
October 2019

Screening performance of abbreviated versions of the UPSIT smell test.

J Neurol 2019 Aug 3;266(8):1897-1906. Epub 2019 May 3.

Preventive Neurology Unit, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.

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http://link.springer.com/10.1007/s00415-019-09340-x
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http://dx.doi.org/10.1007/s00415-019-09340-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647236PMC
August 2019

Genetic risk of Parkinson disease and progression:: An analysis of 13 longitudinal cohorts.

Neurol Genet 2019 Aug 9;5(4):e348. Epub 2019 Jul 9.

Laboratory of Neurogenetics (H.I., C.B., H.L.L., F.F., D.G.H., A.B.S., M.A.N.), National Institute on Aging, National Institutes of Health, Bethesda; Data Tecnica International (H.I., M.A.N.), Glen Echo, MD; Precision Neurology Program (G.L., C.R.S.), Harvard Medical School, Brigham and Women's Hospital; Neurogenomics Laboratory (G.L., C.R.S.), Harvard Medical School, Brigham and Women's Hospital; Ann Romney Center for Neurologic Diseases (G.L., C.R.S.), Brigham and Women's Hospital, Boston, MA; The Norwegian Centre for Movement Disorders (J.M.-G., G.A.), Stavanger University Hospital; Department of Chemistry (J.M.-G., G.A.), Bioscience and Environmental Engineering, University of Stavanger, Norway; Assistance-Publique Hôpitaux de Paris (J.-C.C.), ICM, INSERM UMRS 1127, CNRS 7225, ICM, Department of Neurology and CIC Neurosciences, Pitié-Salpêtrière Hospital, Paris, France; Department of Neurology (L.P., M.T.), Oslo University Hospital, Norway; Department of Neurology (M.N., B.R.B., B.P.W.), Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Centre, Nijmegen, The Netherlands; Michael J Fox Foundation (S.J.H.), New York; Translational Genome Sciences (K.-D.H.N, K.E.), Biogen, Cambridge, MA; Department of Neurology University of Pennsylvania (J.R.), Philadelphia, PA; Department of Biostatistics and Computational Biology (S.E.), University of Rochester, NY; Department of Computer Science (F.F.), University of Illinois Urbana-Champaign; Department of Neurology (P.A.), Center for Health + Technology, University of Rochester, NY; Department of Clinical Neurosciences (K.M.S., R.W.), University of Cambridge, John van Geest Centre for Brain Repair, UK; Department of Pathology and Laboratory Medicine (V.M.V.D.), Center for Neurodegenerative Disease Research, Parelman School of Medicine at the University of Pennsylvania, Philadelphia; Genetics and Pharmacogenomics (A.G.D.-W.), Merck Research Laboratory, Boston, MA; Statistical Genetics (A.G.D.-W.), Biogen, Cambridge, MA; Institut du cerveau et de la moelle épinière ICM (A.B., F.D.); Sorbonne Université SU (A.B.); INSERM UMR (A.B.), Paris, France; Department of Neurology (G.A.), Stavanger University Hospital, Norway; Preventive Neurology Unit (A.J.N.), Wolfson Institute of Preventive Medicine, Queen Mary University of London; Department of Molecular Neuroscience (A.J.N.), UCL Institute of Neurology, London, UK; Department of Neurology (O.-B.T.), Haukeland University Hospital; University of Bergen (O.-B.T.), Bergen, Norway; Department of Neurology (J.R.E.), Nottingham University NHS Trust, UK; Centre for Clinical Brain Sciences (D.P.B.), University of Edinburgh; Anne Rowling Regenerative Neurology Clinic (D.P.B.), University of Edinburgh; Usher Institute of Population Health Sciences and Informatics (D.P.B.), University of Edinburgh, Scotland; Department of Medical and Molecular Genetics (C.E.W.), Indiana University, Indianapolis; Department of Neurology (D.K.S.), Beth Israel Deaconess Medical Center; Harvard Medical School (D.K.S.), Boston; Voyager Therapeutics (B.R.), Cambridge, MA; Department of Neurology (B.R.), University of Rochester School of Medicine, NY; Institute of Clinical Medicine (M.T.), University of Oslo, Norway; German Center for Neurodegenerative Diseases-Tubingen (P.H.); HIH Tuebingen (P.H.), Germany; Department of Psychiatry (D.W.), University of Pennsylvania School of Medicine; Department of Veterans Affairs (D.W.), Philadelphia, PA; and Department of Clinical Neurosciences (R.A.B., C.H.W.-G.), University of Cambridge, UK; Department of Neurology (J.J.V.H.), Leiden University Medical Center, The Netherlands.

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http://dx.doi.org/10.1212/NXG.0000000000000348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659137PMC
August 2019

The BRadykinesia Akinesia INcoordination (BRAIN) Tap Test: Capturing the Sequence Effect.

Mov Disord Clin Pract 2019 Jul 25;6(6):462-469. Epub 2019 Jun 25.

Department of Clinical and Movement Neurosciences Institute of Neurology Queen Square, University College London, London UK.

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http://dx.doi.org/10.1002/mdc3.12798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660282PMC
July 2019

Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis.

Ann Neurol 2019 Apr 13;85(4):470-481. Epub 2019 Mar 13.

Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1002/ana.25431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450729PMC
April 2019

Association between diabetes and subsequent Parkinson disease: A record-linkage cohort study.

Neurology 2018 07 13;91(2):e139-e142. Epub 2018 Jun 13.

From the Reta Lila Weston Institute of Neurological Studies, Department of Molecular Neurosciences (E.D.P.-F., A.J.N., T.T.W.), and Queen Square Brain Bank for Neurological Disorders (E.D.P.-F., T.T.W.), UCL Institute of Neurology, London; Unit of Health-Care Epidemiology (R.G., J.P.), Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Population Health, University of Oxford; and Preventive Neurology Unit (A.J.N.), Wolfson Institute of Preventive Medicine, Queen Mary University of London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000005771DOI Listing
July 2018

No laughing matter: subacute degeneration of the spinal cord due to nitrous oxide inhalation.

J Neurol 2018 May 3;265(5):1089-1095. Epub 2018 Mar 3.

The Royal London Hospital, Emergency Care and Acute Medicine Clinical Academic Group, Neuroscience, Barts Health NHS Trust, London, UK.

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http://dx.doi.org/10.1007/s00415-018-8801-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937900PMC
May 2018

Dopamine reuptake transporter-single-photon emission computed tomography and transcranial sonography as imaging markers of prediagnostic Parkinson's disease.

Mov Disord 2018 03 30;33(3):478-482. Epub 2018 Jan 30.

Department of Clinical Neurosciences, Royal Free Campus, UCL Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1002/mds.27282DOI Listing
March 2018

The BRAIN test: a keyboard-tapping test to assess disability and clinical features of multiple sclerosis.

J Neurol 2018 Feb 4;265(2):285-290. Epub 2017 Dec 4.

Reta Lila Weston Institute of Neurological Studies, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1007/s00415-017-8690-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808056PMC
February 2018

Observations on a 2-Step Approach to Screening for Parkinson Disease.

JAMA Neurol 2017 12;74(12):1506

Reta Lila Weston Institute, UCL Institute of Neurology, London, England.

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http://dx.doi.org/10.1001/jamaneurol.2017.3202DOI Listing
December 2017

Technologies Assessing Limb Bradykinesia in Parkinson's Disease.

J Parkinsons Dis 2017 ;7(1):65-77

UCL Institute of Neurology, Queen Square, London, UK.

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http://dx.doi.org/10.3233/JPD-160878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302048PMC
November 2017

Nonsyndromic Parkinson disease in a family with autosomal dominant optic atrophy due to mutations.

Neurol Genet 2017 Oct 22;3(5):e188. Epub 2017 Sep 22.

Department of Molecular Neuroscience (D.S.L., J.H., N.W.W., H.H., H.P.-F.), UCL Institute of Neurology, London, UK; MRC Toxicology Unit (S.H.Y.L., L.M.M.), Leicester, UK; Reta Lila Weston Institute of Neurological Studies (A.J.N.), UCL Institute of Neurology, London, UK; and Neurogenetics Laboratory (H.H.), National Hospital for Neurology and Neurosurgery, London, UK.

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http://dx.doi.org/10.1212/NXG.0000000000000188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610041PMC
October 2017

Subtle motor disturbances in PREDICT-PD participants.

J Neurol Neurosurg Psychiatry 2017 03 16;88(3):212-217. Epub 2016 Dec 16.

Department of Molecular Neuroscience, Reta Lila Weston Institute, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1136/jnnp-2016-314524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529958PMC
March 2017

Constipation preceding Parkinson's disease: a systematic review and meta-analysis.

J Neurol Neurosurg Psychiatry 2016 Jul 7;87(7):710-6. Epub 2015 Sep 7.

Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1136/jnnp-2015-311680DOI Listing
July 2016

Challenges of modifying disease progression in prediagnostic Parkinson's disease.

Lancet Neurol 2016 05 16;15(6):637-48. Epub 2016 Mar 16.

Parkinson's Disease Research, August Pi i Sunyer Biomedical Research Institute, University of Barcelona, Barcelona, Spain; Parkinson Disease and Movement Disorder Unit, Neurology Service, Hospital Clínic de Barcelona, IDIBAPS, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Universidad de Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(16)00060-0DOI Listing
May 2016

Mendelian Randomization - the Key to Understanding Aspects of Parkinson's Disease Causation?

Mov Disord 2016 Apr 23;31(4):478-83. Epub 2015 Dec 23.

Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1002/mds.26492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943230PMC
April 2016

Systematic review and meta-analysis of salivary protein concentration in Parkinson's disease.

Mov Disord 2015 Dec 19;30(14):1971-2. Epub 2015 Nov 19.

Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

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http://dx.doi.org/10.1002/mds.26462DOI Listing
December 2015

Elevated salivary protein in Parkinson's disease and salivary DJ-1 as a potential marker of disease severity.

Parkinsonism Relat Disord 2015 Oct 23;21(10):1251-5. Epub 2015 Jul 23.

Mucosal & Salivary Biology Division, Floor 17 Tower Wing, King's College London Dental Institute, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2015.07.021DOI Listing
October 2015

Web-based assessment of Parkinson's prodromal markers identifies GBA variants.

Mov Disord 2015 Jun 13;30(7):1002-3. Epub 2015 May 13.

Reta Lila Weston Institute, UCL Institute of Neurology.

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http://dx.doi.org/10.1002/mds.26249DOI Listing
June 2015

Bradykinesia-akinesia incoordination test: validating an online keyboard test of upper limb function.

PLoS One 2014 29;9(4):e96260. Epub 2014 Apr 29.

Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0096260PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004565PMC
November 2014

Bone health in Parkinson's disease: a systematic review and meta-analysis.

J Neurol Neurosurg Psychiatry 2014 Oct 11;85(10):1159-66. Epub 2014 Mar 11.

Reta Lila Weston Institute of Neurological Studies, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1136/jnnp-2013-307307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173751PMC
October 2014

Rapid-onset flaccid paraplegia caused by multiple myeloma dumbbell tumour.

Pract Neurol 2014 Aug 3;14(4):268-9. Epub 2014 Jan 3.

Reta Lila Weston Institute for Neurological Studies, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1136/practneurol-2013-000767DOI Listing
August 2014

A service development study of the assessment and management of fracture risk in Parkinson's disease.

J Neurol 2014 Jun 10;261(6):1153-9. Epub 2014 Apr 10.

Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University London, 4 Newark Street, London, E1 2AT, UK,

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http://dx.doi.org/10.1007/s00415-014-7333-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072921PMC
June 2014

Familial camptocormia: from dystonia to myopathy.

J Neurol Neurosurg Psychiatry 2012 Mar 15;83(3):350-1. Epub 2011 Jul 15.

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http://dx.doi.org/10.1136/jnnp.2011.246561DOI Listing
March 2012

Stiff person syndrome.

Pract Neurol 2011 Oct;11(5):272-82

Department of Neuroscience and Trauma, Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1136/practneurol-2011-000071DOI Listing
October 2011