Alan Yueh-Luen Lee

Alan Yueh-Luen Lee

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Alan Yueh-Luen Lee

Alan Yueh-Luen Lee

Publications by authors named "Alan Yueh-Luen Lee"

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36Publications

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Mitochondrial oxidative stress by Lon-PYCR1 maintains an immunosuppressive tumor microenvironment that promotes cancer progression and metastasis.

Cancer Lett 2020 Apr 25;474:138-150. Epub 2020 Jan 25.

National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan; Department of Biotechnology, College of Life Science, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2020.01.019DOI Listing
April 2020

A time-saving-modified Giemsa stain is a better diagnostic method of Helicobacter pylori infection compared with the rapid urease test.

J Clin Lab Anal 2019 Nov 15:e23110. Epub 2019 Nov 15.

National Institute of Cancer Research, National Health Research Institutes, Zhunan, Taiwan.

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http://dx.doi.org/10.1002/jcla.23110DOI Listing
November 2019

AXL phosphorylates and up-regulates TNS2 and its implications in IRS-1-associated metabolism in cancer cells.

J Biomed Sci 2018 Nov 12;25(1):80. Epub 2018 Nov 12.

Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan.

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http://dx.doi.org/10.1186/s12929-018-0465-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233515PMC
November 2018

Identification of Novel Cdc7 Kinase Inhibitors as Anti-Cancer Agents that Target the Interaction with Dbf4 by the Fragment Complementation and Drug Repositioning Approach.

EBioMedicine 2018 Oct 5;36:241-251. Epub 2018 Oct 5.

National Institute of Cancer Research, National Health Research Institutes, Miaoli 35053, Taiwan; Department of Biotechnology, College of Life Science, Kaohsiung Medical University, Kaohsiung 80708, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S23523964183038
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http://dx.doi.org/10.1016/j.ebiom.2018.09.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197782PMC
October 2018

The Novel VEGF121-VEGF165 Fusion Attenuates Angiogenesis and Drug Resistance via Targeting VEGFR2-HIF-1α-VEGF165/Lon Signaling Through PI3K-AKT-mTOR Pathway.

Curr Cancer Drug Targets 2016 ;16(3):275-86

National Institute of Cancer Research, National Health Research Institutes, 35 Keyan Rd., Zhunan, Miaoli 35053, Taiwan.

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http://dx.doi.org/10.2174/156800961603160206125352DOI Listing
November 2016

Warfarin and coumarin-like Murraya paniculata extract down-regulate EpCAM-mediated cell adhesion: individual components versus mixture for studying botanical metastatic chemopreventives.

Sci Rep 2016 08 2;6:30549. Epub 2016 Aug 2.

Cancer Metastasis Alert and Prevention Center, and Biopharmaceutical Photocatalysis, State Key Laboratory of Photocatalysis on Energy and Environment, Fuzhou University, Fuzhou 350002, China.

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http://dx.doi.org/10.1038/srep30549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969747PMC
August 2016

Mitochondrial Lon protease controls ROS-dependent apoptosis in cardiomyocyte under hypoxia.

Mitochondrion 2015 Jul 25;23:7-16. Epub 2015 Apr 25.

Graduate Institute of Natural Products, School of Traditional Chinese Medicine, College of Medicine, and Chinese Herbal Medicine Research Team, Healthy Aging Research Center, Chang Gung University, Taoyuan 33302, Taiwan; Department of Cosmetic Science and Research Center for Industry of Human Ecology, Chang Gung University of Science and Technology, Taoyuan 33302, Taiwan; Immunology Consortium, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.mito.2015.04.004DOI Listing
July 2015

Cdc6 cooperates with c-Myc to promote genome instability and epithelial to mesenchymal transition EMT in zebrafish.

Oncotarget 2014 Aug;5(15):6300-11

Department of Bioscience Technology, Chung Yuan Christian University, Chung-Li, Taiwan; Center for Nanotechnology, Chung Yuan Christian University, Chung-Li, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171631PMC
http://dx.doi.org/10.18632/oncotarget.2204DOI Listing
August 2014

Structural basis for DNA-mediated allosteric regulation facilitated by the AAA+ module of Lon protease.

Acta Crystallogr D Biol Crystallogr 2014 Feb 17;70(Pt 2):218-30. Epub 2014 Jan 17.

Department of Agricultural Chemistry, National Taiwan University, Taipei 10617, Taiwan.

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http://dx.doi.org/10.1107/S139900471302631XDOI Listing
February 2014

Expression of E-cadherin, Twist, and p53 and their prognostic value in patients with oral squamous cell carcinoma.

J Cancer Res Clin Oncol 2013 Oct 30;139(10):1735-44. Epub 2013 Aug 30.

Laboratory of Physiology, Mackay Memorial Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1007/s00432-013-1499-9DOI Listing
October 2013

Antioxidants from the leaves of Cinnamomum kotoense.

Nat Prod Commun 2010 Jun;5(6):911-2

Department of Intensive Care Medicine, Chi-Mei Medical Centre, Tainan 710, Taiwan, ROC.

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June 2010

DNA-binding specificity of the Lon protease alpha-domain from Brevibacillus thermoruber WR-249.

Biochem Biophys Res Commun 2009 Oct 28;388(1):62-6. Epub 2009 Jul 28.

Institute of Biochemical Sciences, National Taiwan University, Taipei, Taiwan.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0901476
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http://dx.doi.org/10.1016/j.bbrc.2009.07.118DOI Listing
October 2009

Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.

J Biol Chem 2008 Mar 2;283(12):7713-20. Epub 2008 Jan 2.

Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1074/jbc.M710245200DOI Listing
March 2008

(1)H, (13)C and (15)N resonance assignments of alpha-domain for Bacillus subtilis Lon protease.

Biomol NMR Assign 2007 Dec 8;1(2):201-3. Epub 2007 Nov 8.

Institute of Biomedical Sciences, Nankang, Taipei, Taiwan, ROC.

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http://link.springer.com/10.1007/s12104-007-9056-6
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http://dx.doi.org/10.1007/s12104-007-9056-6DOI Listing
December 2007

The Mre11/Rad50/Nbs1 complex plays an important role in the prevention of DNA rereplication in mammalian cells.

J Biol Chem 2007 Nov 22;282(44):32243-55. Epub 2007 Aug 22.

Department of Molecular Experimental Medicine, The Scripps Research Institute, La Jolla, California 92037, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M705486200
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http://dx.doi.org/10.1074/jbc.M705486200DOI Listing
November 2007

The ATR-mediated S phase checkpoint prevents rereplication in mammalian cells when licensing control is disrupted.

J Cell Biol 2007 Nov;179(4):643-57

Department of Molecular Experimental Medicine and 2Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://www.jcb.org/lookup/doi/10.1083/jcb.200704138
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http://dx.doi.org/10.1083/jcb.200704138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2080923PMC
November 2007

The Mre11 complex mediates the S-phase checkpoint through an interaction with replication protein A.

Mol Cell Biol 2007 Sep 25;27(17):6053-67. Epub 2007 Jun 25.

Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1128/MCB.00532-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952149PMC
September 2007

The Mre11-Rad50-Nbs1 complex acts both upstream and downstream of ataxia telangiectasia mutated and Rad3-related protein (ATR) to regulate the S-phase checkpoint following UV treatment.

J Biol Chem 2007 Aug 25;282(31):22939-52. Epub 2007 May 25.

Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1074/jbc.M702162200DOI Listing
August 2007

Functional domains of Brevibacillus thermoruber lon protease for oligomerization and DNA binding: role of N-terminal and sensor and substrate discrimination domains.

J Biol Chem 2004 Aug 4;279(33):34903-12. Epub 2004 Jun 4.

Institute of Biological Chemistry, Academia Sinica, Taipei 115.

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http://dx.doi.org/10.1074/jbc.M403562200DOI Listing
August 2004