Publications by authors named "Alan Wells"

100Publications

Injected Versus Sponge-Applied Mitomycin C (MMC) During Modified Trabeculectomy in New Zealand White Rabbit Model.

Transl Vis Sci Technol 2020 Oct 20;9(11):23. Epub 2020 Oct 20.

Department of Health Promotion and Development, University of Pittsburgh School of Nursing, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1167/tvst.9.11.23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585388PMC
October 2020

A Perspective on Therapeutic Pan-Resistance in Metastatic Cancer.

Int J Mol Sci 2020 Oct 3;21(19). Epub 2020 Oct 3.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.3390/ijms21197304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582598PMC
October 2020

Association between fetal sex and maternal plasma microRNA responses to prenatal alcohol exposure: evidence from a birth outcome-stratified cohort.

Biol Sex Differ 2020 09 10;11(1):51. Epub 2020 Sep 10.

Department of Neuroscience and Experimental Therapeutics, College of Medicine, Medical Research and Education Bldg., Texas A&M University Health Science Center, 8447 Riverside Parkway, Bryan, TX, 77807-3260, USA.

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http://dx.doi.org/10.1186/s13293-020-00327-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488011PMC
September 2020

SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected hospitalized COVID-19 patients.

J Gen Virol 2020 Nov 21;101(11):1156-1169. Epub 2020 Aug 21.

Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1099/jgv.0.001481DOI Listing
November 2020

Prostate cancer liver metastasis: Dormancy and resistance to therapy.

Semin Cancer Biol 2020 Jul 12. Epub 2020 Jul 12.

Center of Clinical Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2020.07.004DOI Listing
July 2020

Leveraging Bayesian networks and information theory to learn risk factors for breast cancer metastasis.

BMC Bioinformatics 2020 Jul 10;21(1):298. Epub 2020 Jul 10.

Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

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http://dx.doi.org/10.1186/s12859-020-03638-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350636PMC
July 2020

Assessing Immune Response to SARS-CoV-2 Infection.

Immunotargets Ther 2020 11;9:111-114. Epub 2020 Jun 11.

Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

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http://dx.doi.org/10.2147/ITT.S264138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295455PMC
June 2020

Integrative microphysiological tissue systems of cancer metastasis to the liver.

Semin Cancer Biol 2020 Jun 21. Epub 2020 Jun 21.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15261, USA; VA Pittsburgh Healthcare System, Pittsburgh, PA 15213, USA; UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15213, USA; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15260, USA; Department of Computational & Systems Biology, University of Pittsburgh, Pittsburgh, PA 15260, USA.

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http://dx.doi.org/10.1016/j.semcancer.2020.06.010DOI Listing
June 2020

Prenatal Antidepressant Use and Risk of Adverse Neonatal Outcomes.

Pediatrics 2020 07 8;146(1). Epub 2020 Jun 8.

OptumLabs, Cambridge, Massachusetts; and.

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http://dx.doi.org/10.1542/peds.2019-2493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329255PMC
July 2020

Mesenchymal Stem Cell/Multipotent Stromal Cell Augmentation of Wound Healing: Lessons from the Physiology of Matrix and Hypoxia Support.

Am J Pathol 2020 07 12;190(7):1370-1381. Epub 2020 Apr 12.

Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania; R&D Service, VA Pittsburgh Health System, Pittsburgh, Pennsylvania; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2020.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369572PMC
July 2020

Patterns of prenatal antidepressant exposure and risk of preeclampsia and postpartum haemorrhage.

Paediatr Perinat Epidemiol 2020 09 24;34(5):597-606. Epub 2020 Mar 24.

Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1111/ppe.12660DOI Listing
September 2020

Expression of E-cadherin and specific CXCR3 isoforms impact each other in prostate cancer.

Cell Commun Signal 2019 12 12;17(1):164. Epub 2019 Dec 12.

Department of Pathology, University of Pittsburgh, S713 Scaife Hall, 3550 Terrace St, Pittsburgh, PA, 15261, USA.

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http://dx.doi.org/10.1186/s12964-019-0489-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909607PMC
December 2019

Conjunctival goblet cells: Ocular surface functions, disorders that affect them, and the potential for their regeneration.

Ocul Surf 2020 01 14;18(1):19-26. Epub 2019 Nov 14.

McGowan Institute of Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA; Pittsburgh Veterans Affairs Medical Center, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jtos.2019.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004882PMC
January 2020

Focal segmental glomerulosclerosis ACTN4 mutants binding to actin: regulation by phosphomimetic mutations.

Sci Rep 2019 10 29;9(1):15517. Epub 2019 Oct 29.

Departments of Pathology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.

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http://dx.doi.org/10.1038/s41598-019-51825-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820738PMC
October 2019

The pan-therapeutic resistance of disseminated tumor cells: Role of phenotypic plasticity and the metastatic microenvironment.

Semin Cancer Biol 2020 02 31;60:138-147. Epub 2019 Jul 31.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15261, USA; VA Pittsburgh Healthcare System, Pittsburgh, PA 15213, USA. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2019.07.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992520PMC
February 2020

Adult Stem Cell Functioning in the Tumor Micro-Environment.

Int J Mol Sci 2019 May 25;20(10). Epub 2019 May 25.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.3390/ijms20102566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566759PMC
May 2019

A clinical decision support system learned from data to personalize treatment recommendations towards preventing breast cancer metastasis.

PLoS One 2019 8;14(3):e0213292. Epub 2019 Mar 8.

Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213292PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407919PMC
December 2019

The great escape: How metastases of melanoma, and other carcinomas, avoid elimination.

Exp Biol Med (Maywood) 2018 12 6;243(17-18):1245-1255. Epub 2019 Jan 6.

6 Department of Surgery, Allegheny Health Network, Pittsburgh, PA 15224, USA.

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http://dx.doi.org/10.1177/1535370218820287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348591PMC
December 2018

Statin drugs to reduce breast cancer recurrence and mortality.

Breast Cancer Res 2018 11 20;20(1):144. Epub 2018 Nov 20.

Department of Pathology, University of Pittsburgh, Pittsburgh, 15231, PA, USA.

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http://dx.doi.org/10.1186/s13058-018-1066-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247616PMC
November 2018

Statins attenuate outgrowth of breast cancer metastases.

Br J Cancer 2018 10 7;119(9):1094-1105. Epub 2018 Nov 7.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA, 15261, USA.

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http://www.nature.com/articles/s41416-018-0267-7
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http://dx.doi.org/10.1038/s41416-018-0267-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220112PMC
October 2018

The Pro-reparative Engine: Stem Cells Aid Healing by Dampening Inflammation.

Curr Pathobiol Rep 2018 Jun 20;6(2):109-115. Epub 2018 Mar 20.

Departments of Pathology and Bioengineering, and the McGowan, Institute for Regenerative Medicine, University of Pittsburgh, and VA Pittsburgh Health System, Pittsburgh PA 15213 USA.

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http://link.springer.com/10.1007/s40139-018-0167-9
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http://dx.doi.org/10.1007/s40139-018-0167-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157924PMC
June 2018

A systems perspective of heterocellular signaling.

Essays Biochem 2018 10 26;62(4):607-617. Epub 2018 Oct 26.

Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA 99352, U.S.A.

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http://dx.doi.org/10.1042/EBC20180015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309864PMC
October 2018

Concomitant attenuation of HMG-CoA reductase expression potentiates the cancer cell growth-inhibitory effect of statins and expands their efficacy in tumor cells with epithelial characteristics.

Oncotarget 2018 Jun 29;9(50):29304-29315. Epub 2018 Jun 29.

Laboratory of Basic Veterinary Science, United Graduate School of Veterinary Science, Yamaguchi University, Yamaguchi 753-8515, Japan.

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http://dx.doi.org/10.18632/oncotarget.25448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047681PMC
June 2018

The Scottish invasion of pink salmon in 2017.

J Fish Biol 2018 07;93(1):8-11

Fisheries Management Scotland, Edinburgh, UK.

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http://dx.doi.org/10.1111/jfb.13680DOI Listing
July 2018

Conjugated equine estrogen and medroxyprogesterone acetate are associated with decreased risk of breast cancer relative to bioidentical hormone therapy and controls.

PLoS One 2018 16;13(5):e0197064. Epub 2018 May 16.

Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197064PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955567PMC
July 2018

Lipophilic statins limit cancer cell growth and survival, via involvement of Akt signaling.

PLoS One 2018 15;13(5):e0197422. Epub 2018 May 15.

Pathology, University of Pittsburgh, Pittsburgh, PA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197422PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953490PMC
November 2018

Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease.

J Pediatr 2018 07 13;198:76-83.e2. Epub 2018 Apr 13.

Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, University of California San Diego School of Medicine, La Jolla, CA; Department of Pediatrics, Division of Gastroenterology, Rady Children's Hospital, San Diego, CA. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2018.02.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019181PMC
July 2018

Liver 'organ on a chip'.

Exp Cell Res 2018 02 29;363(1):15-25. Epub 2017 Dec 29.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA; Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA 15213, USA; The McGowan Institute of Regenerative Medicine University of Pittsburgh, Pittsburgh, PA 15213, USA; Research and Development Service, VA Pittsburgh Health System, Pittsburgh, PA 15240, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2017.12.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944300PMC
February 2018

Tyro3-mediated phosphorylation of ACTN4 at tyrosines is FAK-dependent and decreases susceptibility to cleavage by m-Calpain.

Int J Biochem Cell Biol 2018 02 20;95:73-84. Epub 2017 Dec 20.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, United States; Pittsburgh VA Health System, Pittsburgh, PA 15213, United States. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2017.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803314PMC
February 2018

Inflammatory cytokine IL-8/CXCL8 promotes tumour escape from hepatocyte-induced dormancy.

Br J Cancer 2018 02 23;118(4):566-576. Epub 2017 Nov 23.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1038/bjc.2017.414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830588PMC
February 2018

Biomarker identification for statin sensitivity of cancer cell lines.

Biochem Biophys Res Commun 2018 01 14;495(1):659-665. Epub 2017 Nov 14.

Department of Computational & Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X173224
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http://dx.doi.org/10.1016/j.bbrc.2017.11.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827944PMC
January 2018

Bi-directional exosome-driven intercommunication between the hepatic niche and cancer cells.

Mol Cancer 2017 Nov 14;16(1):172. Epub 2017 Nov 14.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1186/s12943-017-0740-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686836PMC
November 2017

Low Infection-Related Re-Admission Rates in a Retrospective of 4725 Children with Appendicitis Using a Clinical Pathway in a Tertiary Care Pediatric Center.

Surg Infect (Larchmt) 2017 Nov/Dec;18(8):894-903. Epub 2017 Oct 24.

1 Department of Pediatrics, University of California , San Diego, School of Medicine, San Diego, California.

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http://dx.doi.org/10.1089/sur.2017.104DOI Listing
June 2018

Multipotent stromal cells/mesenchymal stem cells and fibroblasts combine to minimize skin hypertrophic scarring.

Stem Cell Res Ther 2017 09 5;8(1):193. Epub 2017 Sep 5.

Department of Pathology, University of Pittsburgh, 3550 Terrace St., Scaife Hall, S-713, Pittsburgh, PA, 15261, USA.

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http://dx.doi.org/10.1186/s13287-017-0644-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585998PMC
September 2017

Tyro3 carboxyl terminal region confers stability and contains the autophosphorylation sites.

Biochem Biophys Res Commun 2017 08 28;490(3):1074-1079. Epub 2017 Jun 28.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, United States; Pittsburgh VA Health System, Pittsburgh, PA 15213, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2017.06.168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553559PMC
August 2017

Reply: Role of Rhinoplasty in Transsexual Patients.

Plast Reconstr Surg 2017 10;140(4):625e-626e

FACIALTEAM Surgical Group, HC Marbella International Hospital, Málaga, Spain.

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http://dx.doi.org/10.1097/PRS.0000000000003707DOI Listing
October 2017

Friend turned foe: E-cadherin perversely protects micrometastases.

Authors:
Alan Wells Bo Ma

Transl Androl Urol 2017 Apr;6(2):338-340

Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.21037/tau.2017.03.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422706PMC
April 2017

In Children With Nonalcoholic Fatty Liver Disease, Zone 1 Steatosis Is Associated With Advanced Fibrosis.

Clin Gastroenterol Hepatol 2018 03 7;16(3):438-446.e1. Epub 2017 Mar 7.

Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California; Department of Gastroenterology, Rady Children's Hospital San Diego, San Diego, California. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2017.02.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589478PMC
March 2018

Facial Feminization Surgery: Simultaneous Hair Transplant during Forehead Reconstruction.

Plast Reconstr Surg 2017 Mar;139(3):573-584

Marbella, Málaga, Spain From the FACIALTEAM Surgical Group, MHC International Hospital.

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http://dx.doi.org/10.1097/PRS.0000000000003149DOI Listing
March 2017

CXCL11 Expression by Keratinocytes Occurs Transiently Between Reaching Confluence and Cellular Compaction.

Adv Wound Care (New Rochelle) 2016 Dec;5(12):517-526

Department of Pathology, McGowan Institute for Regenerative Medicine, VA Pittsburgh Health System, University of Pittsburgh , Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1089/wound.2015.0680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165675PMC
December 2016

Mesenchymal stem cells/multipotent stromal cells (MSCs) are glycolytic and thus glucose is a limiting factor of in vitro models of MSC starvation.

Stem Cell Res Ther 2016 12 1;7(1):179. Epub 2016 Dec 1.

Department of Pathology, University of Pittsburgh School of Medicine, Scaife Hall, 3550 Terrace St, Pittsburgh, PA, 15261, USA.

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http://dx.doi.org/10.1186/s13287-016-0436-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134064PMC
December 2016

Distinct Osteomimetic Response of Androgen-Dependent and Independent Human Prostate Cancer Cells to Mechanical Action of Fluid Flow: Prometastatic Implications.

Prostate 2017 02 3;77(3):321-333. Epub 2016 Nov 3.

Valencia Institute of Pathology, Catholic University of Valencia School of Medicine and Odontology, Valencia, Spain.

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http://dx.doi.org/10.1002/pros.23270DOI Listing
February 2017

Liver protects metastatic prostate cancer from induced death by activating E-cadherin signaling.

Hepatology 2016 11 23;64(5):1725-1742. Epub 2016 Sep 23.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074910PMC
http://dx.doi.org/10.1002/hep.28755DOI Listing
November 2016

Liver metastases: Microenvironments and ex-vivo models.

Exp Biol Med (Maywood) 2016 Sep 6;241(15):1639-52. Epub 2016 Jul 6.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, USA Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA 15213, USA McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA Pittsburgh VA Medical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999624PMC
http://dx.doi.org/10.1177/1535370216658144DOI Listing
September 2016

Macrophage phenotypic subtypes diametrically regulate epithelial-mesenchymal plasticity in breast cancer cells.

BMC Cancer 2016 07 7;16:419. Epub 2016 Jul 7.

Department of Pathology, University of Pittsburgh, and Pittsburgh VA Health System, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1186/s12885-016-2411-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936312PMC
July 2016

Pericytes: A newly recognized player in wound healing.

Wound Repair Regen 2016 03 10;24(2):204-14. Epub 2016 Mar 10.

Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1111/wrr.12415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036393PMC
March 2016

Time series modeling of live-cell shape dynamics for image-based phenotypic profiling.

Integr Biol (Camb) 2016 Jan 11;8(1):73-90. Epub 2015 Dec 11.

Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058786PMC
http://dx.doi.org/10.1039/c5ib00283dDOI Listing
January 2016

The anatomical distribution of genetic associations.

Nucleic Acids Res 2015 Dec 19;43(22):10804-20. Epub 2015 Nov 19.

Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA

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http://nar.oxfordjournals.org/content/43/22/10804.full.pdf
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http://nar.oxfordjournals.org/lookup/doi/10.1093/nar/gkv1262
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http://dx.doi.org/10.1093/nar/gkv1262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678833PMC
December 2015

Skin tissue repair: Matrix microenvironmental influences.

Matrix Biol 2016 Jan 14;49:25-36. Epub 2015 Aug 14.

Department of Health Development and Promotion, University of Pittsburgh, Pittsburgh, PA 15213 USA; McGowan Institute of Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA 15213 USA.

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http://dx.doi.org/10.1016/j.matbio.2015.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753148PMC
January 2016

Use of ChemoFx® for Identification of Effective Treatments in Epithelial Ovarian Cancer.

PLoS Curr 2015 Jul 13;7. Epub 2015 Jul 13.

Department of Obstetrics and Gynecology, Allegheny Health Network, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1371/currents.eogt.8b0b6fffc7b999b34bc4c8152edbf237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506277PMC
July 2015

Differential regulation of pericyte function by the CXC receptor 3.

Wound Repair Regen 2015 Nov-Dec;23(6):785-96. Epub 2015 Oct 19.

Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1111/wrr.12346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662923PMC
October 2016

Tandem phosphorylation within an intrinsically disordered region regulates ACTN4 function.

Sci Signal 2015 May 26;8(378):ra51. Epub 2015 May 26.

Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA 15260, USA.

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http://dx.doi.org/10.1126/scisignal.aaa1977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522051PMC
May 2015

CXCR3 in carcinoma progression.

Histol Histopathol 2015 Jul 9;30(7):781-92. Epub 2015 Feb 9.

Department of Pathology, University of Pittsburgh and VA Pittsburgh Health System and University of Pittsburgh Cancer Institute, Pittsburgh, USA.

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http://dx.doi.org/10.14670/HH-11-594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571436PMC
July 2015

Lung epithelial cells induce both phenotype alteration and senescence in breast cancer cells.

PLoS One 2015 30;10(1):e0118060. Epub 2015 Jan 30.

Department of Pathology, University of Pittsburgh, and Pittsburgh VA Health System, Pittsburgh, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118060PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311980PMC
January 2016

Selection of models for the analysis of risk-factor trees: leveraging biological knowledge to mine large sets of risk factors with application to microbiome data.

Bioinformatics 2015 May 6;31(10):1607-13. Epub 2015 Jan 6.

Division of Statistical Genomics, Washington University School of Medicine, St. Louis, MO, USA, Department of Biology, Washington University, St. Louis, MO, USA, The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA and Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426830PMC
May 2015

Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion.

Sci Rep 2014 Dec 23;4:7593. Epub 2014 Dec 23.

1] Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15213, USA [2] Department of Computational &Systems Biology, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15260, USA.

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http://dx.doi.org/10.1038/srep07593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274516PMC
December 2014

Tenascin-C Signaling in melanoma.

Cell Adh Migr 2015 ;9(1-2):125-30

a Department of Pathology.

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http://dx.doi.org/10.4161/19336918.2014.972781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422811PMC
December 2015

Twelve tips for teaching social determinants of health in medicine.

Med Teach 2015 Jul 6;37(7):647-652. Epub 2014 Nov 6.

a Herbert Wertheim College of Medicine , USA.

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July 2015

α-Actinin-4 is required for amoeboid-type invasiveness of melanoma cells.

J Biol Chem 2014 Nov 8;289(47):32717-28. Epub 2014 Oct 8.

From the Departments of Pathology and the Laboratory and Pathology Service, Pittsburgh Veterans Affairs Health System, Pittsburgh, Pennsylvania 15213

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http://dx.doi.org/10.1074/jbc.M114.579185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239623PMC
November 2014

A microphysiological system model of therapy for liver micrometastases.

Exp Biol Med (Maywood) 2014 Sep 12;239(9):1170-9. Epub 2014 May 12.

Departments of Pathology, Cell Biology, Pharmaceutical Sciences, and Bioengineering, and the McGowan Institute for Regenerative Medicine, University of Pittsburgh and Pittsburgh VA Health System, Pittsburgh, PA 15213, USA

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http://dx.doi.org/10.1177/1535370214532596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574864PMC
September 2014

PKCδ regulates force signaling during VEGF/CXCL4 induced dissociation of endothelial tubes.

PLoS One 2014 3;9(4):e93968. Epub 2014 Apr 3.

Department of Pathology, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974837PMC
January 2015

Engineering liver.

Hepatology 2014 Oct 19;60(4):1426-34. Epub 2014 May 19.

Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA.

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http://dx.doi.org/10.1002/hep.27150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176555PMC
October 2014

The mitogen-activated protein (MAP) kinases p38 and extracellular signal-regulated kinase (ERK) are involved in hepatocyte-mediated phenotypic switching in prostate cancer cells.

Authors:
Bo Ma Alan Wells

J Biol Chem 2014 Apr 11;289(16):11153-61. Epub 2014 Mar 11.

From the Department of Pathology, University of Pittsburgh and Pittsburgh Veterans Affairs Medical Center, Pittsburgh Pennsylvania 15261.

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http://www.jbc.org/cgi/doi/10.1074/jbc.M113.540237
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036254PMC
April 2014

Hepatic nonparenchymal cells drive metastatic breast cancer outgrowth and partial epithelial to mesenchymal transition.

Breast Cancer Res Treat 2014 Apr 9;144(3):551-60. Epub 2014 Mar 9.

Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1007/s10549-014-2875-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009995PMC
April 2014

Cell type-specific expression analysis to identify putative cellular mechanisms for neurogenetic disorders.

J Neurosci 2014 Jan;34(4):1420-31

Preston M. Green Department of Electrical and Systems Engineering, Washington University in St. Louis, St. Louis, Missouri 63130, and Departments of Genetics and Psychiatry, Washington University School of Medicine in St. Louis, St. Louis, Missouri 63110.

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http://dx.doi.org/10.1523/JNEUROSCI.4488-13.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898298PMC
January 2014

Matrikine and matricellular regulators of EGF receptor signaling on cancer cell migration and invasion.

Lab Invest 2014 Jan 18;94(1):31-40. Epub 2013 Nov 18.

Department of Pathology, University of Pittsburgh, Pittsburgh VAMC, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1038/labinvest.2013.132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038324PMC
January 2014

Skin wound healing and scarring: fetal wounds and regenerative restitution.

Birth Defects Res C Embryo Today 2012 Dec;96(4):325-33

Department of Health Promotion and Development, School of Nursing, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://doi.wiley.com/10.1002/bdrc.21024
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http://dx.doi.org/10.1002/bdrc.21024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967791PMC
December 2012

PKCδ localization at the membrane increases matrix traction force dependent on PLCγ1/EGFR signaling.

PLoS One 2013 14;8(10):e77434. Epub 2013 Oct 14.

Department of Pathology, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796482PMC
June 2014

Pericyte regulation of vascular remodeling through the CXC receptor 3.

Arterioscler Thromb Vasc Biol 2013 Dec 17;33(12):2818-29. Epub 2013 Oct 17.

From the Department of Pathology (R.J.B., M.E.B., A.W.) and Department of Bioengineering (W.C.W.C.), University of Pittsburgh, PA; and Pittsburgh Veterans Affairs Medical Center, Pittsburgh, PA (R.J.B., M.E.B., A.W.).

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http://dx.doi.org/10.1161/ATVBAHA.113.302012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591000PMC
December 2013

The dormancy dilemma: quiescence versus balanced proliferation.

Cancer Res 2013 Jul 21;73(13):3811-6. Epub 2013 Jun 21.

Department of Pathology and Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702639PMC
July 2013

Targeting tumor cell motility as a strategy against invasion and metastasis.

Trends Pharmacol Sci 2013 May 6;34(5):283-9. Epub 2013 Apr 6.

Department of Pathology, University of Pittsburgh and Pittsburgh VAHS, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1016/j.tips.2013.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640670PMC
May 2013

The matrikine tenascin-C protects multipotential stromal cells/mesenchymal stem cells from death cytokines such as FasL.

Tissue Eng Part A 2013 Sep 1;19(17-18):1972-83. Epub 2013 May 1.

Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1089/ten.TEA.2012.0568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725854PMC
September 2013

The carboxyl tail of alpha-actinin-4 regulates its susceptibility to m-calpain and thus functions in cell migration and spreading.

Int J Biochem Cell Biol 2013 Jun 1;45(6):1051-63. Epub 2013 Mar 1.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15261, United States.

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http://dx.doi.org/10.1016/j.biocel.2013.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633689PMC
June 2013

Modeling the assembly of the multiple domains of α-actinin-4 and its role in actin cross-linking.

Biophys J 2013 Feb;104(3):705-15

Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.bpj.2012.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566466PMC
February 2013

Modeling boundary conditions for balanced proliferation in metastatic latency.

Clin Cancer Res 2013 Mar 17;19(5):1063-70. Epub 2013 Jan 17.

Department of Bioengineering, University of Pittsburgh and Taylor Allderdice High School, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-3180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594128PMC
March 2013

The Beginning of the End: CXCR3 Signaling in Late-Stage Wound Healing.

Adv Wound Care (New Rochelle) 2012 Dec;1(6):244-248

Department of Pathology, University of Pittsburgh Medical Center , Pittsburgh, Pennsylvania. ; Department of Pathology, Veterans Administration Medical Center , Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1089/wound.2011.0355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623597PMC
December 2012

Workflow organization in pathology.

Clin Lab Med 2012 Dec;32(4):601-22

Department of Pathology, University of Pittsburgh Medical Center, UPMC Shadyside Hospital Suite, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1016/j.cll.2012.07.008DOI Listing
December 2012

Melanoma cell invasiveness is promoted at least in part by the epidermal growth factor-like repeats of tenascin-C.

J Invest Dermatol 2013 Jan 6;133(1):210-20. Epub 2012 Sep 6.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0022202X1535962
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http://dx.doi.org/10.1038/jid.2012.263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519964PMC
January 2013

An IP-10 (CXCL10)-derived peptide inhibits angiogenesis.

PLoS One 2012 16;7(7):e40812. Epub 2012 Jul 16.

Tuskegee University, Center for Cancer Research, Tuskegee, Alabama, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397949PMC
March 2013

Mesenchymal-epithelial transition (MET) as a mechanism for metastatic colonisation in breast cancer.

Cancer Metastasis Rev 2012 Dec;31(3-4):469-78

Department of Surgery, St. Vincent's Hospital, University of Melbourne, 29 Regent St., Fitzroy, Melbourne, Australia 3065.

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http://dx.doi.org/10.1007/s10555-012-9377-5DOI Listing
December 2012