Alan Saven

Alan Saven

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Alan Saven

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Novel therapeutics in hairy cell leukemia.

Expert Rev Hematol 2019 Sep 8:1-5. Epub 2019 Sep 8.

Division of Hematology and Oncology, Scripps Clinic , La Jolla , CA , USA.

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https://www.tandfonline.com/doi/full/10.1080/17474086.2019.1
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http://dx.doi.org/10.1080/17474086.2019.1652589DOI Listing
September 2019

Secondary malignancies after treatment with single-agent vemurafenib in two patients with refractory hairy cell leukemia.

Leuk Lymphoma 2019 May 15;60(5):1331-1333. Epub 2018 Oct 15.

a Division of Hematology-Oncology , Scripps Clinic , La Jolla , CA , USA.

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http://dx.doi.org/10.1080/10428194.2018.1519809DOI Listing
May 2019

Treatment outcomes and secondary cancer incidence in young patients with hairy cell leukaemia.

Br J Haematol 2016 Nov 28;175(3):402-409. Epub 2016 Jun 28.

Leukemia Service, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.1111/bjh.14207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539949PMC
November 2016

Spontaneous Iliopsoas Muscle Hemorrhage Secondary to Ibrutinib (Imbruvica; Pharmacyclics): Brief Report.

J Investig Med High Impact Case Rep 2016 Apr-Jun;4(2):2324709616648457. Epub 2016 May 9.

Scripps Green Hospital, La Jolla, CA, USA.

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http://dx.doi.org/10.1177/2324709616648457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871198PMC
May 2016

Current Therapy and New Directions in the Treatment of Hairy Cell Leukemia: A Review.

JAMA Oncol 2016 Jan;2(1):123-9

Division of Hematology/Oncology, Scripps Clinic, La Jolla, California.

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http://dx.doi.org/10.1001/jamaoncol.2015.4134DOI Listing
January 2016

Targeting Mutant BRAF in Relapsed or Refractory Hairy-Cell Leukemia.

N Engl J Med 2015 Oct 9;373(18):1733-47. Epub 2015 Sep 9.

From the Institute of Hematology, Department of Medicine, and Centro di Ricerca Emato-Oncologico (CREO), University of Perugia, and Ospedale Santa Maria della Misericordia, Perugia (E.T., L.D.C., F.F., S.A., M.C., M.P.M., B.F.), the Department of Experimental, Diagnostic, and Specialty Medicine, Units of Hematology and Hematopathology, Bologna University School of Medicine, Bologna (A.B., S.A.P., P.L.Z.), Hematology Unit, Centro Trapianti e Terapie Cellulari Carlo Melzi, Dipartimento di Science Mediche Sperimentali e Cliniche, Azienda Ospedaliero Universitaria, Udine (F.Z.), the Department of Cellular Biotechnologies and Hematology, Division of Hematology, Sapienza University, Rome (A.P., R.F.), the Hematology and Bone Marrow Transplant Unit, Azienda Ospedaliera Regionale San Carlo, Potenza (M.C.), the Division of Hematology, Department of Translational Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara (D.R.), Hematology Unit, Ospedale Ferrarotto, Catania (G.M.), the Department of Onco-Hematology, Fondazione IRCCS, Policlinico San Matteo, Pavia (M.V.), Hematology Unit, Spedali Civili, Brescia (A. Anastasia), the Department of Medicine, Section of Hematology, University of Verona, Verona (A. Ambrosetti), Onco-Hematology Unit, Fondazione di Ricerca e Cura S.S. Giovanni Paolo II, Campobasso (V.F.), Institute of Hematology 1, IRCCS, Azienda Ospedaliero Universitaria San Martino-Istituto Nazionale per la Ricerca sul Cancro, Genoa (A.M.C.), the Department of Hematology, Azienda Ospedaliero Universitaria Ospedali Riuniti, Ancona (P.L.), and the Hematology and Bone Marrow Transplant Unit, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo (A.R.) - all in Italy; Leukemia Service (J.H.P., S.S.C., R.L.L., O.A-W., M.S.T.,) and Dermatology Service (M.E.L.), the Department of Medicine, Human Oncology and Pathogenesis Program (S.S., Y.R.C., E.K., R.L.L., C.Y.P., M.F.B., O.A-W.), the Departments of Epidemiology and Biostatistics (S.D.), Pathology (C.Y.P.), and Pharmaco

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http://dx.doi.org/10.1056/NEJMoa1506583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811324PMC
October 2015

In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs.

Authors:
Ayalew Tefferi Hagop Kantarjian S Vincent Rajkumar Lawrence H Baker Jan L Abkowitz John W Adamson Ranjana Hira Advani James Allison Karen H Antman Robert C Bast John M Bennett Edward J Benz Nancy Berliner Joseph Bertino Ravi Bhatia Smita Bhatia Deepa Bhojwani Charles D Blanke Clara D Bloomfield Linda Bosserman Hal E Broxmeyer John C Byrd Fernando Cabanillas George Peter Canellos Bruce A Chabner Asher Chanan-Khan Bruce Cheson Bayard Clarkson Susan L Cohn Gerardo Colon-Otero Jorge Cortes Steven Coutre Massimo Cristofanilli Walter J Curran George Q Daley Daniel J DeAngelo H Joachim Deeg Lawrence H Einhorn Harry P Erba Francisco J Esteva Elihu Estey Isaiah J Fidler James Foran Stephen Forman Emil Freireich Charles Fuchs James N George Morie A Gertz Sergio Giralt Harvey Golomb Peter Greenberg Jordan Gutterman Robert I Handin Samuel Hellman Paulo Marcelo Hoff Ronald Hoffman Waun Ki Hong Mary Horowitz Gabriel N Hortobagyi Clifford Hudis Jean Pierre Issa Bruce Evan Johnson Philip W Kantoff Kenneth Kaushansky David Khayat Fadlo R Khuri Thomas J Kipps Margaret Kripke Robert A Kyle Richard A Larson Theodore S Lawrence Ross Levine Michael P Link Scott M Lippman Sagar Lonial Gary H Lyman Maurie Markman John Mendelsohn Neal J Meropol Yoav Messinger Therese M Mulvey Susan O'Brien Roman Perez-Soler Raphael Pollock Josef Prchal Oliver Press Jerald Radich Kanti Rai Saul A Rosenberg Jacob M Rowe Hope Rugo Carolyn D Runowicz Brenda M Sandmaier Alan Saven Andrew I Schafer Charles Schiffer Mikkael A Sekeres Richard T Silver Lillian L Siu David P Steensma F Marc Stewart Wendy Stock Richard Stone Rainer Storb Louise C Strong Martin S Tallman Michael Thompson Naoto T Ueno Richard A Van Etten Julie M Vose Peter H Wiernik Eric P Winer Anas Younes Andrew D Zelenetz Charles A LeMaistre

Mayo Clin Proc 2015 Aug 23;90(8):996-1000. Epub 2015 Jul 23.

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http://dx.doi.org/10.1016/j.mayocp.2015.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365030PMC
August 2015

Retrospective analysis of relative dose intensity in patients with non-Hodgkin lymphoma receiving CHOP-based chemotherapy and pegfilgrastim.

Am J Clin Oncol 2014 Dec;37(6):603-10

*Senior Adult Oncology Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL †Amgen Inc., Thousand Oaks ‡Scripps Clinic, La Jolla, CA.

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http://dx.doi.org/10.1097/COC.0000000000000141DOI Listing
December 2014

Hairy cell leukemia: a 'hair-raising' update.

Expert Rev Hematol 2014 Oct 22;7(5):659-69. Epub 2014 Aug 22.

Division of Hematology/Oncology, Scripps Clinic, 10666 N Torrey Pines Rd MS 312, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1586/17474086.2014.951629DOI Listing
October 2014

Masquerade without a mass: an unusual cause of severe acute pancreatitis.

J Gastrointest Oncol 2013 Mar;4(1):114-7

Department of Internal Medicine, Department of Medicine, Scripps Clinic/Green Hospital, La Jolla, CA, USA.

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http://dx.doi.org/10.3978/j.issn.2078-6891.2012.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562626PMC
March 2013

Targeting B lymphoma with nanoparticles bearing glycan ligands of CD22.

Leuk Lymphoma 2012 Feb 24;53(2):208-10. Epub 2011 Aug 24.

Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA, USA.

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http://dx.doi.org/10.3109/10428194.2011.604755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197974PMC
February 2012

My treatment approach to hairy cell leukemia.

Mayo Clin Proc 2012 Jan;87(1):67-76

Division of Hematology and Oncology, Scripps Clinic, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.mayocp.2011.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498175PMC
January 2012

Primary intraocular lymphoma: a review.

J Neurooncol 2011 Nov 31;105(2):127-34. Epub 2011 May 31.

Division of Hematology/Oncology, Scripps Clinic, 10666 N. Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1007/s11060-011-0618-1DOI Listing
November 2011

Development of cladribine at Scripps for hairy cell leukemia and current results.

Leuk Lymphoma 2011 Jun 19;52 Suppl 2:29-33. Epub 2011 Apr 19.

Division of Hematology/Oncology, Scripps Clinic, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.3109/10428194.2011.569621DOI Listing
June 2011

Hairy cell leukemia: current therapies and future directions.

Expert Rev Hematol 2010 Dec;3(6):679-83

Division of Hematology/Oncology, Scripps Clinic, 10666 N Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1586/ehm.10.67DOI Listing
December 2010

Beyond hairy cell: the activity of cladribine in other hematologic malignancies.

Blood 2010 Oct 15;116(16):2884-96. Epub 2010 Jul 15.

Division of Hematology/Oncology, Scripps Clinic Medical Group, La Jolla, CA 92037, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2010-02-24
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http://dx.doi.org/10.1182/blood-2010-02-246140DOI Listing
October 2010

In vivo targeting of B-cell lymphoma with glycan ligands of CD22.

Blood 2010 Jun 24;115(23):4778-86. Epub 2010 Feb 24.

Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA, USA.

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http://dx.doi.org/10.1182/blood-2009-12-257386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890185PMC
June 2010

Pegfilgrastim on the Same Day Versus Next Day of Chemotherapy in Patients With Breast Cancer, Non-Small-Cell Lung Cancer, Ovarian Cancer, and Non-Hodgkin's Lymphoma: Results of Four Multicenter, Double-Blind, Randomized Phase II Studies.

J Oncol Pract 2010 May;6(3):133-40

Sarah Cannon Research Institute, Nashville; West Clinic, Memphis, TN; Penn State Cancer Institute, Hershey, PA; Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH; M. D. Anderson Cancer Center at Orlando, Orlando, FL; North County Oncology Medical Clinic, Oceanside; Amgen, Thousand Oaks; and Ida M. and Cecil H. Green Cancer Center, Scripps Clinic, La Jolla, CA.

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http://dx.doi.org/10.1200/JOP.091094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868638PMC
May 2010

Very long-term eradication of minimal residual disease in patients with hairy cell leukemia after a single course of cladribine.

Blood 2010 Mar 7;115(10):1893-6. Epub 2010 Jan 7.

Division of Hematology/Oncology, Scripps Clinic Medical Group, 10666 N. Torrey Pines Rd, MS217, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1182/blood-2009-10-251645DOI Listing
March 2010

Cladribine in the treatment of hairy cell leukemia: initial and subsequent results.

Leuk Lymphoma 2009 Oct;50 Suppl 1:12-7

Division of Hematology/Oncology, Scripps Clinic, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.3109/10428190903142083DOI Listing
October 2009

Cladribine in indolent non-Hodgkin's lymphoma.

Expert Rev Anticancer Ther 2008 Apr;8(4):535-45

Division of Hematology/Oncology, Scripps Clinic, 10666 N. Torrey Pines Road, M/S 217 La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1586/14737140.8.4.535DOI Listing
April 2008

Hairy cell leukemia.

Cancer Treat Res 2008 ;142:193-209

Scripps Clinic, La Jolla, CA, USA.

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http://dx.doi.org/10.1007/978-0-387-73744-7_8DOI Listing
March 2008

Understanding hairy cell leukemia genetics.

Leuk Lymphoma 2007 Apr;48(4):653-4

Division of Hematology/Oncology, Scripps Clinic, Ida M. and Cecil H. Green Cancer Center, La Jolla, CA, USA.

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http://www.tandfonline.com/doi/full/10.1080/1042819070120397
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http://dx.doi.org/10.1080/10428190701203970DOI Listing
April 2007

How valid is using cancer registries' data to identify acquired immunodeficiency syndrome-related non-Hodgkin's lymphoma?

Cancer Causes Control 2007 Mar 18;18(2):135-42. Epub 2007 Jan 18.

Department of Medicine, UCI Medical Center, University of California Irvine, Orange, CA 92868, USA.

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http://dx.doi.org/10.1007/s10552-006-0096-5DOI Listing
March 2007

Prolonged follow-up after initial therapy with 2-chlorodeoxyadenosine in patients with indolent non-Hodgkin lymphoma: results of Cancer and Leukemia Group B Study 9153.

Cancer 2006 Dec;107(12):2817-25

Division of Hematology-Oncology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1002/cncr.22344DOI Listing
December 2006

Cladribine in hairy cell leukemia.

Hematol Oncol Clin North Am 2006 Oct;20(5):1109-23

Division of Hematology/Oncology, M/S 217, Scripps Clinic, 10666 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.hoc.2006.06.008DOI Listing
October 2006

Reactive thrombocytosis associated with a pheochromocytoma.

Thromb Haemost 2005 Aug;94(2):460-2

Division of Hematology and Oncology, Scripps Clinic, La Jolla, CA 92037, USA.

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August 2005

Combinatorial antibody libraries from cancer patients yield ligand-mimetic Arg-Gly-Asp-containing immunoglobulins that inhibit breast cancer metastasis.

Proc Natl Acad Sci U S A 2004 Dec 24;101(49):17210-5. Epub 2004 Nov 24.

Department of Molecular and Experimental Medicine, The Scripps Research Institute and The Skaggs Institute of Chemical Biology, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.0407869101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC534417PMC
December 2004

Cladribine: from the bench to the bedside--focus on hairy cell leukemia.

Expert Rev Anticancer Ther 2004 Oct;4(5):745-57

Division of Hematology/Oncology, Scripps Clinics, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1586/14737140.4.5.745DOI Listing
October 2004

CD52 expression in hairy cell leukemia.

Am J Hematol 2003 Dec;74(4):227-30

Division of Hematopathology, Scripps Clinic Laboratories, Scripps Clinic, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1002/ajh.10428DOI Listing
December 2003

Evidence for ozone formation in human atherosclerotic arteries.

Science 2003 Nov;302(5647):1053-6

Department of Chemistry, The Scripps Research Institute and The Skaggs Institute for Chemical Biology, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1126/science.1089525DOI Listing
November 2003

Phase 2 study of rituximab in the treatment of cladribine-failed patients with hairy cell leukemia.

Blood 2003 Aug 27;102(3):810-3. Epub 2003 Mar 27.

Division of Hematology/Oncology and Department of Pathology, Scripps Clinic, La Jolla, CA, USA.

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http://dx.doi.org/10.1182/blood-2003-01-0014DOI Listing
August 2003

Activated integrin alphavbeta3 cooperates with metalloproteinase MMP-9 in regulating migration of metastatic breast cancer cells.

Proc Natl Acad Sci U S A 2003 Aug 21;100(16):9482-7. Epub 2003 Jul 21.

Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.1633689100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC170944PMC
August 2003

Hairy cell leukemia: an update.

Curr Opin Hematol 2003 Jul;10(4):258-66

Division of Hematology/Oncology, Scripps Clinic, La Jolla, California 92037, USA.

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July 2003

Extended follow-up of patients with hairy cell leukemia after treatment with cladribine.

J Clin Oncol 2003 Mar;21(5):891-6

Division of Hematology/Oncology, The Scripps Research Institute, La Jolla, CA, USA.

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http://dx.doi.org/10.1200/JCO.2003.05.093DOI Listing
March 2003

Cladribine in the treatment of hairy-cell leukaemia.

Best Pract Res Clin Haematol 2003 Mar;16(1):101-16

Division of Hematology and Oncology, Scripps Clinic, 10666 North Torrey Pines Road, La Jolla, CA 92037, USA.

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March 2003