Alan R Tall

Alan R Tall

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Alan R Tall

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Inflammasomes, neutrophil extracellular traps, and cholesterol.

J Lipid Res 2019 Apr 19;60(4):721-727. Epub 2019 Feb 19.

Department of Pediatrics, Section Molecular Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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http://dx.doi.org/10.1194/jlr.S091280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446695PMC
April 2019

Leducq Transatlantic Network on Clonal Hematopoiesis and Atherosclerosis.

Circ Res 2019 Feb;124(4):481-483

Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY (A.R.T.).

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http://dx.doi.org/10.1161/CIRCRESAHA.119.314677DOI Listing
February 2019

How broken sleep promotes cardiovascular disease.

Nature 2019 02;566(7744):329-330

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http://dx.doi.org/10.1038/d41586-019-00393-6DOI Listing
February 2019

Cholesterol Mass Efflux Capacity, Incident Cardiovascular Disease, and Progression of Carotid Plaque.

Arterioscler Thromb Vasc Biol 2019 Jan;39(1):89-96

From the Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York (S. Shea, L.T., L.Y.-C., A.R.T.).

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.118.311366
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http://dx.doi.org/10.1161/ATVBAHA.118.311366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310062PMC
January 2019

Macrophage Inflammation, Erythrophagocytosis, and Accelerated Atherosclerosis in Jak2 Mice.

Circ Res 2018 Nov;123(11):e35-e47

From the Division of Molecular Medicine, Department of Medicine (W.W., W.L., T.F., Y.W., Y.T., C.W., B.C., I.T., A.R.T., N.W.), Columbia University Medical Center, New York, NY.

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http://dx.doi.org/10.1161/CIRCRESAHA.118.313283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309796PMC
November 2018

Plasma high density lipoproteins: Therapeutic targeting and links to atherogenic inflammation.

Authors:
Alan R Tall

Atherosclerosis 2018 09 4;276:39-43. Epub 2018 Jul 4.

Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY, 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.07.004DOI Listing
September 2018

Trials and Tribulations of CETP Inhibitors.

Circ Res 2018 01 10;122(1):106-112. Epub 2017 Oct 10.

From the Division of Molecular Medicine, Department of Medicine, Columbia University, New York (A.R.T.); and Departments of Genetics and Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia (D.J.R.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.311978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756107PMC
January 2018

Exome-wide association study of plasma lipids in >300,000 individuals.

Authors:
Dajiang J Liu Gina M Peloso Haojie Yu Adam S Butterworth Xiao Wang Anubha Mahajan Danish Saleheen Connor Emdin Dewan Alam Alexessander Couto Alves Philippe Amouyel Emanuele Di Angelantonio Dominique Arveiler Themistocles L Assimes Paul L Auer Usman Baber Christie M Ballantyne Lia E Bang Marianne Benn Joshua C Bis Michael Boehnke Eric Boerwinkle Jette Bork-Jensen Erwin P Bottinger Ivan Brandslund Morris Brown Fabio Busonero Mark J Caulfield John C Chambers Daniel I Chasman Y Eugene Chen Yii-Der Ida Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu John M Connell Francesco Cucca L Adrienne Cupples Scott M Damrauer Gail Davies Ian J Deary George Dedoussis Joshua C Denny Anna Dominiczak Marie-Pierre Dubé Tapani Ebeling Gudny Eiriksdottir Tõnu Esko Aliki-Eleni Farmaki Mary F Feitosa Marco Ferrario Jean Ferrieres Ian Ford Myriam Fornage Paul W Franks Timothy M Frayling Ruth Frikke-Schmidt Lars G Fritsche Philippe Frossard Valentin Fuster Santhi K Ganesh Wei Gao Melissa E Garcia Christian Gieger Franco Giulianini Mark O Goodarzi Harald Grallert Niels Grarup Leif Groop Megan L Grove Vilmundur Gudnason Torben Hansen Tamara B Harris Caroline Hayward Joel N Hirschhorn Oddgeir L Holmen Jennifer Huffman Yong Huo Kristian Hveem Sehrish Jabeen Anne U Jackson Johanna Jakobsdottir Marjo-Riitta Jarvelin Gorm B Jensen Marit E Jørgensen J Wouter Jukema Johanne M Justesen Pia R Kamstrup Stavroula Kanoni Fredrik Karpe Frank Kee Amit V Khera Derek Klarin Heikki A Koistinen Jaspal S Kooner Charles Kooperberg Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo Lakka Claudia Langenberg Anne Langsted Lenore J Launer Torsten Lauritzen David C M Liewald Li An Lin Allan Linneberg Ruth J F Loos Yingchang Lu Xiangfeng Lu Reedik Mägi Anders Malarstig Ani Manichaikul Alisa K Manning Pekka Mäntyselkä Eirini Marouli Nicholas G D Masca Andrea Maschio James B Meigs Olle Melander Andres Metspalu Andrew P Morris Alanna C Morrison Antonella Mulas Martina Müller-Nurasyid Patricia B Munroe Matt J Neville Jonas B Nielsen Sune F Nielsen Børge G Nordestgaard Jose M Ordovas Roxana Mehran Christoper J O'Donnell Marju Orho-Melander Cliona M Molony Pieter Muntendam Sandosh Padmanabhan Colin N A Palmer Dorota Pasko Aniruddh P Patel Oluf Pedersen Markus Perola Annette Peters Charlotta Pisinger Giorgio Pistis Ozren Polasek Neil Poulter Bruce M Psaty Daniel J Rader Asif Rasheed Rainer Rauramaa Dermot F Reilly Alex P Reiner Frida Renström Stephen S Rich Paul M Ridker John D Rioux Neil R Robertson Dan M Roden Jerome I Rotter Igor Rudan Veikko Salomaa Nilesh J Samani Serena Sanna Naveed Sattar Ellen M Schmidt Robert A Scott Peter Sever Raquel S Sevilla Christian M Shaffer Xueling Sim Suthesh Sivapalaratnam Kerrin S Small Albert V Smith Blair H Smith Sangeetha Somayajula Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kathleen E Stirrups Nathan Stitziel Konstantin Strauch Heather M Stringham Praveen Surendran Hayato Tada Alan R Tall Hua Tang Jean-Claude Tardif Kent D Taylor Stella Trompet Philip S Tsao Jaakko Tuomilehto Anne Tybjaerg-Hansen Natalie R van Zuydam Anette Varbo Tibor V Varga Jarmo Virtamo Melanie Waldenberger Nan Wang Nick J Wareham Helen R Warren Peter E Weeke Joshua Weinstock Jennifer Wessel James G Wilson Peter W F Wilson Ming Xu Hanieh Yaghootkar Robin Young Eleftheria Zeggini He Zhang Neil S Zheng Weihua Zhang Yan Zhang Wei Zhou Yanhua Zhou Magdalena Zoledziewska Joanna M M Howson John Danesh Mark I McCarthy Chad A Cowan Goncalo Abecasis Panos Deloukas Kiran Musunuru Cristen J Willer Sekar Kathiresan

Nat Genet 2017 Dec 30;49(12):1758-1766. Epub 2017 Oct 30.

Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709146PMC
December 2017

Mitochondrial Oxidative Stress Promotes Atherosclerosis and Neutrophil Extracellular Traps in Aged Mice.

Arterioscler Thromb Vasc Biol 2017 08 8;37(8):e99-e107. Epub 2017 Jun 8.

From the Division of Cardiology (Y.W.), Division of Molecular Medicine (W.W, A.R.T., I.T.), Division of Molecular Medicine, Department of Medicine (N.W.), Columbia University Medical Center, New York, NY.

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http://dx.doi.org/10.1161/ATVBAHA.117.309580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535797PMC
August 2017

Increasing Lipolysis and Reducing Atherosclerosis.

Authors:
Alan R Tall

N Engl J Med 2017 07;377(3):280-283

From Columbia University Medical Center, New York.

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http://dx.doi.org/10.1056/NEJMe1706907DOI Listing
July 2017

Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity.

Cell Metab 2017 Jun 4;25(6):1294-1304.e6. Epub 2017 May 4.

Division of Molecular Medicine, Department of Medicine, Columbia University, 630 West 168 Street, P&S 8-401, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.cmet.2017.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514787PMC
June 2017

Evacetrapib and Cardiovascular Outcomes in High-Risk Vascular Disease.

N Engl J Med 2017 05;376(20):1933-1942

From the Cleveland Clinic Coordinating Center for Clinical Research (C5Research), Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland (A.M.L., V.M., E.M., K.W., D.M., S.E.N.); South Australian Heart and Medical Research Institute, University of Adelaide, Adelaide (S.J.N.), and School of Medical Sciences, University of New South Wales, Sydney (P.J.B.) - both in Australia; Eli Lilly, Indianapolis (J.S.R., G.R., B.V., G.W.); Washington Cardiovascular Associates, Medstar Research Institute, Washington, DC (H.B.B.); Centre for Cardiovascular Science, University of Edinburgh, Edinburgh (K.A.A.F.); Beth Israel Deaconess Medical Center, Boston (C.M.G.); Duke University Medical Center, Durham, NC (C.G.); Université Sorbonne Paris 6, ACTION Study Group, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Institut de Cardiologie, Paris (G.M.); Penn Heart and Vascular Center, Philadelphia (D.R.); Columbia University, New York (A.R.T.), and Saratoga Cardiology Associates, Saratoga Springs (D.K.) - both in New York; St. Michael's Hospital, Toronto (S.G.), Recherche Médicale Saint-Jérôme, Saint-Jérôme, QC (Y.P.), and Centre de Santé et de Services Sociaux du Nord de Lanaudière-Centre Hospitalier Régional de Lanaud, Saint-Charles-Borromée, QC (S.K.) - all in Canada; Instituto Cardiovascular de Buenos Aires, Buenos Aires (D.C.); University of Texas Southwestern Medical Center, Dallas (D.K.M.); Heart Institute (InCor)-University of São Paulo Medical School, São Paulo (J.C.N.); Hospital Central Dr. Ignacio Morones Prieto, San Luis Potosi, Mexico (J.L.L.-P.); the First Affiliated Hospital of Harbin Medical University, Harbin, China (W.L.); and South Oklahoma Heart Research, Oklahoma City (N.T.).

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http://dx.doi.org/10.1056/NEJMoa1609581DOI Listing
May 2017

Cardiovascular disease: Commonality with cancer.

Nature 2017 03 22;543(7643):45-47. Epub 2017 Feb 22.

Human Oncology and Pathogenesis Program and Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

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http://www.nature.com/articles/nature21505
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http://dx.doi.org/10.1038/nature21505DOI Listing
March 2017

A New Approach to PCSK9 Therapeutics.

Circ Res 2017 03 6;120(7):1063-1065. Epub 2017 Mar 6.

From the Division of Molecular Medicine, Department of Medicine, Columbia University Medical Center, New York, NY.

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.117.31061
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http://dx.doi.org/10.1161/CIRCRESAHA.117.310610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848492PMC
March 2017

LNK/SH2B3 Loss of Function Promotes Atherosclerosis and Thrombosis.

Circ Res 2016 Sep 18;119(6):e91-e103. Epub 2016 Jul 18.

From the Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY (W.W., Y.T., Y.W., L.T., C.W., A.R.T., N.W.); Division of Hematology, Children's Hospital of Philadelphia, PA (W.T.); Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia (J.B., W.T.); and Human Oncology and Pathogenesis Program (R.L.L.) and Leukemia Service, Department of Medicine (R.L.L.), Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.308955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016083PMC
September 2016

Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Endothelial Cells Accelerates Atherosclerosis in Mice.

Arterioscler Thromb Vasc Biol 2016 07 19;36(7):1328-37. Epub 2016 May 19.

From the Division of Molecular Medicine, Department of Medicine (M.W., P.F., A.E.B., M.M.M., V.N., S.A., C.L.W., A.R.T.), Naomi Berrie Diabetes Center (K.T., D.A.), and Department of Pathology, Obstetrics, and Gynaecology (I.W.T., J.K.), Columbia University, New York, NY; Section on Molecular Genetics, Department of Pediatrics, University Medical Center Groningen, Groningen, The Netherlands (M.W.); Department of Diabetes, Endocrinology, and Metabolism, Medical Hospital of Tokyo Medical and Dental University, Tokyo, Japan (K.T.); and Section on Molecular Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (J.S.P.).

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http://dx.doi.org/10.1161/ATVBAHA.115.306670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919153PMC
July 2016

Enhanced Megakaryopoiesis and Platelet Activity in Hypercholesterolemic, B6-Ldlr-/-, Cdkn2a-Deficient Mice.

Circ Cardiovasc Genet 2016 Jun 20;9(3):213-22. Epub 2016 Apr 20.

From the Department of Medicine, Division of Molecular Medicine, Columbia University, New York, NY.

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http://dx.doi.org/10.1161/CIRCGENETICS.115.001294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917436PMC
June 2016

High-Density Lipoproteins, Endothelial Function, and Mendelian Randomization.

Circ Res 2016 06;119(1):13-5

From the Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY (M.W., N.W., A.R.T.); and Department of Pediatrics, Section on Molecular Genetics, University Medical Center Groningen, Groningen, The Netherlands (M.W.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.309116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922507PMC
June 2016

Disordered haematopoiesis and athero-thrombosis.

Eur Heart J 2016 Apr 10;37(14):1113-21. Epub 2016 Feb 10.

Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1093/eurheartj/ehv718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823636PMC
April 2016

Cholesterol in platelet biogenesis and activation.

Blood 2016 Apr 29;127(16):1949-53. Epub 2016 Feb 29.

Division of Molecular Medicine, Department of Medicine, Columbia University Medical Center, New York, NY.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2016-01-63
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http://dx.doi.org/10.1182/blood-2016-01-631259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841038PMC
April 2016

Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.

Sci Transl Med 2016 Apr;8(333):333ra50

Institute of Innate Immunity, University Hospital Bonn, 53127 Bonn, Germany. German Center of Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany. Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, 7489 Trondheim, Norway. Department of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA 01605, USA.

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http://dx.doi.org/10.1126/scitranslmed.aad6100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878149PMC
April 2016

Atherosclerosis: Successes, Surprises, and Future Challenges.

Circ Res 2016 Feb;118(4):531-4

From the Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (P.L.); Department of Medicine, Division of Metabolism, Endocrinology and Nutrition (K.E.B.), and Department of Pathology (K.E.B.), UW Diabetes Institute, University of Washington, Seattle; and Division of Molecular Medicine, Department of Medicine, Columbia University, New York (A.R.T.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.308334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762065PMC
February 2016

Dysfunctional HDL and atherosclerotic cardiovascular disease.

Nat Rev Cardiol 2016 Jan 1;13(1):48-60. Epub 2015 Sep 1.

Pharmacology &Nutritional Sciences and Saha Cardiovascular Research Center, University of Kentucky College of Medicine, Lexington, KY, USA.

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http://dx.doi.org/10.1038/nrcardio.2015.124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245940PMC
January 2016

Increased Systemic and Plaque Inflammation in ABCA1 Mutation Carriers With Attenuation by Statins.

Arterioscler Thromb Vasc Biol 2015 Jul 19;35(7):1663-9. Epub 2015 Feb 19.

From the Department of Vascular Medicine (A.E.B., F.M.v.d.V, E.S.S.) and Department of Medical Biochemistry (M.W.), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; and Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY (A.E.B., S.T., M.W., A.R.T.).

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http://dx.doi.org/10.1161/ATVBAHA.114.304959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484788PMC
July 2015

Cholesterol, inflammation and innate immunity.

Nat Rev Immunol 2015 Feb;15(2):104-16

University of Nice, Unité Mixte de Recherce (UMR), Institut national de la Santé et de la Recherche Médicale U1065, 062104 Nice Cedex 3, France.

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http://dx.doi.org/10.1038/nri3793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669071PMC
February 2015

SORTILIN: many headed hydra.

Circ Res 2015 Feb;116(5):764-6

From the Division of Molecular Medicine, Department of Medicine, Columbia University, New York.

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http://dx.doi.org/10.1161/CIRCRESAHA.115.306036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347864PMC
February 2015

Interleukin-3/granulocyte macrophage colony-stimulating factor receptor promotes stem cell expansion, monocytosis, and atheroma macrophage burden in mice with hematopoietic ApoE deficiency.

Arterioscler Thromb Vasc Biol 2014 May 20;34(5):976-84. Epub 2014 Mar 20.

From the Division of Molecular Medicine, Department of Medicine (M. Wang, M.S., S.A., A.J.M., C.W., I.T., M. Westerterp, A.R.T.) and Department of Pharmacology (M. Wang), Columbia University, New York, NY; Department of Medicine, University of California San Diego, La Jolla (A.G., J.W.); and Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (M. Westerterp).

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http://dx.doi.org/10.1161/ATVBAHA.113.303097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091799PMC
May 2014

Disruption of mammalian target of rapamycin complex 1 in macrophages decreases chemokine gene expression and atherosclerosis.

Circ Res 2014 May 31;114(10):1576-84. Epub 2014 Mar 31.

From the Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY (D.A., H.J., M. Westerterp, A.J.M., M. Wang, A.G., S.A., C.W., A.R.T.); Department of Physiology, Tianjin Medical University, Tianjin, China (D.A., Y.Z.); Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (M. Westerterp); and Department of Medicine, University of California at San Diego, CA (F.A., Y.I.M.).

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http://dx.doi.org/10.1161/CIRCRESAHA.114.302313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058053PMC
May 2014

Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity.

Cell Metab 2014 May;19(5):821-35

Haematopoiesis and Leukocyte Biology, Baker IDI Heart and Diabetes Institute, Melbourne VIC 3004, Australia; Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY 10032, USA; Department of Immunology, Monash University, Melbourne VIC 3004, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2014.03.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048939PMC
May 2014

Activation of liver X receptor decreases atherosclerosis in Ldlr⁻/⁻ mice in the absence of ATP-binding cassette transporters A1 and G1 in myeloid cells.

Arterioscler Thromb Vasc Biol 2014 Feb 5;34(2):279-84. Epub 2013 Dec 5.

From the Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY (M.S.K., A.J.M., S.A., V.N., C.L.W., A.R.T., M.W.); Department of Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY (M.S.K.); and Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, The Netherlands (M.W.).

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http://dx.doi.org/10.1161/ATVBAHA.113.302781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941179PMC
February 2014

ATP-binding cassette transporters, atherosclerosis, and inflammation.

Circ Res 2014 Jan;114(1):157-70

From the Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY (M.W., A.E.B., L.Y.-C., A.J.M., N.W., A.R.T.); Departments of Medical Biochemistry (M.W.) and Vascular Medicine (A.E.B.), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; and Haematopoiesis and Leukocyte Biology, Baker IDI Heart and Diabetes Institute, Melbourne, Australia (A.J.M.).

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http://dx.doi.org/10.1161/CIRCRESAHA.114.300738DOI Listing
January 2014

Proliferating macrophages populate established atherosclerotic lesions.

Circ Res 2014 Jan;114(2):236-8

From the Haematopoiesis and Leukocyte Biology, Baker IDI Heart and Diabetes Institute, Melbourne, Australia (A.J.M.); Department of Immunology, Monash University, Melbourne, Australia (A.J.M.); and Department of Medicine, Division of Molecular Medicine, Columbia University, New York, NY (A.R.T.).

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.113.30281
Publisher Site
http://dx.doi.org/10.1161/CIRCRESAHA.113.302813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332765PMC
January 2014

Translation of high-density lipoprotein function into clinical practice: current prospects and future challenges.

Circulation 2013 Sep;128(11):1256-67

Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY (R.S.R.); Cardiovascular Research Institute, MedStar Research Institute, Washington Hospital Center, Washington, DC (H.B.B.); Atherosclerosis Research Unit, Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA (B.A.); Centre for Vascular Research at the University of New South Wales, Sydney, Australia (P.B.); Dyslipidemia, Atherosclerosis and Inflammation Research Unit 939, National Institute for Health and Medical Research, University of Pierre and Marie Curie - Paris 6, Pitie-Salpetriere Hospital, Paris, France (M.J.C., A.K.) Division of Metabolism, Endocrinology, and Nutrition, University of Washington, Seattle (J.W.H.); Department of Medicine, Columbia University, New York, NY (A.R.T.); and Internal Medicine and Saha Cardiovascular Research Center, University of Kentucky College of Medicine, Lexington (N.R.W.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.000962DOI Listing
September 2013

TLR3 deficiency protects against collagen degradation and medial destruction in murine atherosclerotic plaques.

Atherosclerosis 2013 Jul 9;229(1):52-61. Epub 2013 Apr 9.

Division of Molecular Medicine, Department of Medicine, Columbia University, P&S 8-401, 630 West 168th Street, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2013.03.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771346PMC
July 2013

Pegylation of high-density lipoprotein decreases plasma clearance and enhances antiatherogenic activity.

Circ Res 2013 Jun 23;113(1):e1-e9. Epub 2013 Apr 23.

Division of Molecular Medicine, Department of Medicine, Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.113.301112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905798PMC
June 2013

HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders.

J Exp Med 2013 Feb 14;210(2):339-53. Epub 2013 Jan 14.

Department of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1084/jem.20121357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570097PMC
February 2013

Cholesterol efflux: a novel regulator of myelopoiesis and atherogenesis.

Arterioscler Thromb Vasc Biol 2012 Nov;32(11):2547-52

Department of Medicine, Columbia University, 630W 168th St, College of Physicians and Surgeons 8-401, New York, NY 10032, USA.

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http://dx.doi.org/10.1161/ATVBAHA.112.300134DOI Listing
November 2012

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

Authors:
Zari Dastani Marie-France Hivert Nicholas Timpson John R B Perry Xin Yuan Robert A Scott Peter Henneman Iris M Heid Jorge R Kizer Leo-Pekka Lyytikäinen Christian Fuchsberger Toshiko Tanaka Andrew P Morris Kerrin Small Aaron Isaacs Marian Beekman Stefan Coassin Kurt Lohman Lu Qi Stavroula Kanoni James S Pankow Hae-Won Uh Ying Wu Aurelian Bidulescu Laura J Rasmussen-Torvik Celia M T Greenwood Martin Ladouceur Jonna Grimsby Alisa K Manning Ching-Ti Liu Jaspal Kooner Vincent E Mooser Peter Vollenweider Karen A Kapur John Chambers Nicholas J Wareham Claudia Langenberg Rune Frants Ko Willems-Vandijk Ben A Oostra Sara M Willems Claudia Lamina Thomas W Winkler Bruce M Psaty Russell P Tracy Jennifer Brody Ida Chen Jorma Viikari Mika Kähönen Peter P Pramstaller David M Evans Beate St Pourcain Naveed Sattar Andrew R Wood Stefania Bandinelli Olga D Carlson Josephine M Egan Stefan Böhringer Diana van Heemst Lyudmyla Kedenko Kati Kristiansson Marja-Liisa Nuotio Britt-Marie Loo Tamara Harris Melissa Garcia Alka Kanaya Margot Haun Norman Klopp H-Erich Wichmann Panos Deloukas Efi Katsareli David J Couper Bruce B Duncan Margreet Kloppenburg Linda S Adair Judith B Borja James G Wilson Solomon Musani Xiuqing Guo Toby Johnson Robert Semple Tanya M Teslovich Matthew A Allison Susan Redline Sarah G Buxbaum Karen L Mohlke Ingrid Meulenbelt Christie M Ballantyne George V Dedoussis Frank B Hu Yongmei Liu Bernhard Paulweber Timothy D Spector P Eline Slagboom Luigi Ferrucci Antti Jula Markus Perola Olli Raitakari Jose C Florez Veikko Salomaa Johan G Eriksson Timothy M Frayling Andrew A Hicks Terho Lehtimäki George Davey Smith David S Siscovick Florian Kronenberg Cornelia van Duijn Ruth J F Loos Dawn M Waterworth James B Meigs Josee Dupuis J Brent Richards Benjamin F Voight Laura J Scott Valgerdur Steinthorsdottir Christian Dina Ryan P Welch Eleftheria Zeggini Cornelia Huth Yurii S Aulchenko Gudmar Thorleifsson Laura J McCulloch Teresa Ferreira Harald Grallert Najaf Amin Guanming Wu Cristen J Willer Soumya Raychaudhuri Steve A McCarroll Oliver M Hofmann Ayellet V Segrè Mandy van Hoek Pau Navarro Kristin Ardlie Beverley Balkau Rafn Benediktsson Amanda J Bennett Roza Blagieva Eric Boerwinkle Lori L Bonnycastle Kristina Bengtsson Boström Bert Bravenboer Suzannah Bumpstead Noël P Burtt Guillaume Charpentier Peter S Chines Marilyn Cornelis Gabe Crawford Alex S F Doney Katherine S Elliott Amanda L Elliott Michael R Erdos Caroline S Fox Christopher S Franklin Martha Ganser Christian Gieger Niels Grarup Todd Green Simon Griffin Christopher J Groves Candace Guiducci Samy Hadjadj Neelam Hassanali Christian Herder Bo Isomaa Anne U Jackson Paul R V Johnson Torben Jørgensen Wen H L Kao Augustine Kong Peter Kraft Johanna Kuusisto Torsten Lauritzen Man Li Aloysius Lieverse Cecilia M Lindgren Valeriya Lyssenko Michel Marre Thomas Meitinger Kristian Midthjell Mario A Morken Narisu Narisu Peter Nilsson Katharine R Owen Felicity Payne Ann-Kristin Petersen Carl Platou Christine Proença Inga Prokopenko Wolfgang Rathmann N William Rayner Neil R Robertson Ghislain Rocheleau Michael Roden Michael J Sampson Richa Saxena Beverley M Shields Peter Shrader Gunnar Sigurdsson Thomas Sparsø Klaus Strassburger Heather M Stringham Qi Sun Amy J Swift Barbara Thorand Jean Tichet Tiinamaija Tuomi Rob M van Dam Timon W van Haeften Thijs van Herpt Jana V van Vliet-Ostaptchouk G Bragi Walters Michael N Weedon Cisca Wijmenga Jacqueline Witteman Richard N Bergman Stephane Cauchi Francis S Collins Anna L Gloyn Ulf Gyllensten Torben Hansen Winston A Hide Graham A Hitman Albert Hofman David J Hunter Kristian Hveem Markku Laakso Andrew D Morris Colin N A Palmer Igor Rudan Eric Sijbrands Lincoln D Stein Jaakko Tuomilehto Andre Uitterlinden Mark Walker Richard M Watanabe Goncalo R Abecasis Bernhard O Boehm Harry Campbell Mark J Daly Andrew T Hattersley Oluf Pedersen Inês Barroso Leif Groop Rob Sladek Unnur Thorsteinsdottir James F Wilson Thomas Illig Philippe Froguel Cornelia M van Duijn Kari Stefansson David Altshuler Michael Boehnke Mark I McCarthy Nicole Soranzo Eleanor Wheeler Nicole L Glazer Nabila Bouatia-Naji Reedik Mägi Joshua Randall Paul Elliott Denis Rybin Abbas Dehghan Jouke Jan Hottenga Kijoung Song Anuj Goel Taina Lajunen Alex Doney Christine Cavalcanti-Proença Meena Kumari Nicholas J Timpson Carina Zabena Erik Ingelsson Ping An Jeffrey O'Connell Jian'an Luan Amanda Elliott Steven A McCarroll Rosa Maria Roccasecca François Pattou Praveen Sethupathy Yavuz Ariyurek Philip Barter John P Beilby Yoav Ben-Shlomo Sven Bergmann Murielle Bochud Amélie Bonnefond Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Suzannah J Bumpstead Yii-Der Ida Chen Peter Chines Robert Clarke Lachlan J M Coin Matthew N Cooper Laura Crisponi Ian N M Day Eco J C de Geus Jerome Delplanque Annette C Fedson Antje Fischer-Rosinsky Nita G Forouhi Maria Grazia Franzosi Pilar Galan Mark O Goodarzi Jürgen Graessler Scott Grundy Rhian Gwilliam Göran Hallmans Naomi Hammond Xijing Han Anna-Liisa Hartikainen Caroline Hayward Simon C Heath Serge Hercberg David R Hillman Aroon D Hingorani Jennie Hui Joe Hung Marika Kaakinen Jaakko Kaprio Y Antero Kesaniemi Mika Kivimaki Beatrice Knight Seppo Koskinen Peter Kovacs Kirsten Ohm Kyvik G Mark Lathrop Debbie A Lawlor Olivier Le Bacquer Cécile Lecoeur Yun Li Robert Mahley Massimo Mangino María Teresa Martínez-Larrad Jarred B McAteer Ruth McPherson Christa Meisinger David Melzer David Meyre Braxton D Mitchell Sutapa Mukherjee Silvia Naitza Matthew J Neville Marco Orrù Ruth Pakyz Giuseppe Paolisso Cristian Pattaro Daniel Pearson John F Peden Nancy L Pedersen Andreas F H Pfeiffer Irene Pichler Ozren Polasek Danielle Posthuma Simon C Potter Anneli Pouta Michael A Province Nigel W Rayner Kenneth Rice Samuli Ripatti Fernando Rivadeneira Olov Rolandsson Annelli Sandbaek Manjinder Sandhu Serena Sanna Avan Aihie Sayer Paul Scheet Udo Seedorf Stephen J Sharp Beverley Shields Gunnar Sigurðsson Eric J G Sijbrands Angela Silveira Laila Simpson Andrew Singleton Nicholas L Smith Ulla Sovio Amy Swift Holly Syddall Ann-Christine Syvänen Anke Tönjes André G Uitterlinden Ko Willems van Dijk Dhiraj Varma Sophie Visvikis-Siest Veronique Vitart Nicole Vogelzangs Gérard Waeber Peter J Wagner Andrew Walley Kim L Ward Hugh Watkins Sarah H Wild Gonneke Willemsen Jaqueline C M Witteman John W G Yarnell Diana Zelenika Björn Zethelius Guangju Zhai Jing Hua Zhao M Carola Zillikens Ingrid B Borecki Pierre Meneton Patrik K E Magnusson David M Nathan Gordon H Williams Kaisa Silander Stefan R Bornstein Peter Schwarz Joachim Spranger Fredrik Karpe Alan R Shuldiner Cyrus Cooper Manuel Serrano-Ríos Lars Lind Lyle J Palmer Frank B Hu Paul W Franks Shah Ebrahim Michael Marmot W H Linda Kao Peter Paul Pramstaller Alan F Wright Michael Stumvoll Anders Hamsten Thomas A Buchanan Timo T Valle Jerome I Rotter Brenda W J H Penninx Dorret I Boomsma Antonio Cao Angelo Scuteri David Schlessinger Manuela Uda Aimo Ruokonen Marjo-Riitta Jarvelin Leena Peltonen Vincent Mooser Robert Sladek Kiran Musunuru Albert V Smith Andrew C Edmondson Ioannis M Stylianou Masahiro Koseki James P Pirruccello Daniel I Chasman Christopher T Johansen Sigrid W Fouchier Gina M Peloso Maja Barbalic Sally L Ricketts Joshua C Bis Mary F Feitosa Marju Orho-Melander Olle Melander Xiaohui Li Mingyao Li Yoon Shin Cho Min Jin Go Young Jin Kim Jong-Young Lee Taesung Park Kyunga Kim Xueling Sim Rick Twee-Hee Ong Damien C Croteau-Chonka Leslie A Lange Joshua D Smith Andreas Ziegler Weihua Zhang Robert Y L Zee John B Whitfield John R Thompson Ida Surakka Tim D Spector Johannes H Smit Juha Sinisalo James Scott Juha Saharinen Chiara Sabatti Lynda M Rose Robert Roberts Mark Rieder Alex N Parker Guillaume Pare Christopher J O'Donnell Markku S Nieminen Deborah A Nickerson Grant W Montgomery Wendy McArdle David Masson Nicholas G Martin Fabio Marroni Gavin Lucas Robert Luben Marja-Liisa Lokki Guillaume Lettre Lenore J Launer Edward G Lakatta Reijo Laaksonen Kirsten O Kyvik Inke R König Kay-Tee Khaw Lee M Kaplan Åsa Johansson A Cecile J W Janssens Wilmar Igl G Kees Hovingh Christian Hengstenberg Aki S Havulinna Nicholas D Hastie Tamara B Harris Talin Haritunians Alistair S Hall Leif C Groop Elena Gonzalez Nelson B Freimer Jeanette Erdmann Kenechi G Ejebe Angela Döring Anna F Dominiczak Serkalem Demissie Panagiotis Deloukas Ulf de Faire Gabriel Crawford Yii-der I Chen Mark J Caulfield S Matthijs Boekholdt Themistocles L Assimes Thomas Quertermous Mark Seielstad Tien Y Wong E-Shyong Tai Alan B Feranil Christopher W Kuzawa Herman A Taylor Stacey B Gabriel Hilma Holm Vilmundur Gudnason Ronald M Krauss Jose M Ordovas Patricia B Munroe Jaspal S Kooner Alan R Tall Robert A Hegele John J P Kastelein Eric E Schadt David P Strachan Muredach P Reilly Nilesh J Samani Heribert Schunkert L Adrienne Cupples Manjinder S Sandhu Paul M Ridker Daniel J Rader Sekar Kathiresan

PLoS Genet 2012 29;8(3):e1002607. Epub 2012 Mar 29.

Department of Epidemiology, Biostatistics, and Occupational Health, Jewish General Hospital, Lady Davis Institute, McGill University, Montreal, Canada.

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September 2012

The not-so-simple HDL story: Is it time to revise the HDL cholesterol hypothesis?

Nat Med 2012 Sep;18(9):1344-6

Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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September 2012

Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism.

J Clin Invest 2012 Aug 2;122(8):2807-16. Epub 2012 Jul 2.

Institute for Translational Medicine and Therapeutics, Cardiovascular Institute, and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

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August 2012

Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice.

J Clin Invest 2012 Apr 19;122(4):1262-70. Epub 2012 Mar 19.

Department of Medicine, Columbia University, New York, New York 10032, USA.

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April 2012

Anti-atherogenic mechanisms of high density lipoprotein: effects on myeloid cells.

Biochim Biophys Acta 2012 Mar 16;1821(3):513-21. Epub 2011 Aug 16.

Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY 10032, USA.

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March 2012

Homozygosity for an allele encoding deacetylated FoxO1 protects macrophages from cholesterol-induced inflammation without increasing apoptosis.

Arterioscler Thromb Vasc Biol 2011 Dec 22;31(12):2920-8. Epub 2011 Sep 22.

Department of Medicine, College of Physicians and Surgeons of Columbia University, New York, NY, USA.

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December 2011

n-3 fatty acids ameliorate hepatic steatosis and dysfunction after LXR agonist ingestion in mice.

Biochim Biophys Acta 2011 Sep 13;1811(9):491-7. Epub 2011 Jun 13.

Institute of Human Nutrition, Columbia University Medical Center, New York, NY 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196345PMC
September 2011

Functions of cholesterol ester transfer protein and relationship to coronary artery disease risk.

Authors:
Alan R Tall

J Clin Lipidol 2010 Sep-Oct;4(5):389-93

Columbia University, 630 W 168th Street, New York, NY 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976564PMC
July 2011

Deletion of ABCA1 and ABCG1 impairs macrophage migration because of increased Rac1 signaling.

Circ Res 2011 Jan 9;108(2):194-200. Epub 2010 Dec 9.

Division of Molecular Medicine, Department of Medicine, Columbia University, 630 W 168th Street, New York, NY 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097897PMC
January 2011

Sorting out sortilin.

Authors:
Alan R Tall Ding Ai

Circ Res 2011 Jan;108(2):158-60

Division of Molecular Medicine, Department of Medicine, Columbia University Medical Center.

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January 2011

Increased atherosclerosis in mice with vascular ATP-binding cassette transporter G1 deficiency--brief report.

Arterioscler Thromb Vasc Biol 2010 Nov 12;30(11):2103-5. Epub 2010 Aug 12.

Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY 10032, USA.

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November 2010

Reduced VLDL clearance in Apoe(-/-)Npc1(-/-) mice is associated with increased Pcsk9 and Idol expression and decreased hepatic LDL-receptor levels.

J Lipid Res 2010 Sep 18;51(9):2655-63. Epub 2010 Jun 18.

Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.1194/jlr.M006163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918447PMC
September 2010

Biological, clinical and population relevance of 95 loci for blood lipids.

Authors:
Tanya M Teslovich Kiran Musunuru Albert V Smith Andrew C Edmondson Ioannis M Stylianou Masahiro Koseki James P Pirruccello Samuli Ripatti Daniel I Chasman Cristen J Willer Christopher T Johansen Sigrid W Fouchier Aaron Isaacs Gina M Peloso Maja Barbalic Sally L Ricketts Joshua C Bis Yurii S Aulchenko Gudmar Thorleifsson Mary F Feitosa John Chambers Marju Orho-Melander Olle Melander Toby Johnson Xiaohui Li Xiuqing Guo Mingyao Li Yoon Shin Cho Min Jin Go Young Jin Kim Jong-Young Lee Taesung Park Kyunga Kim Xueling Sim Rick Twee-Hee Ong Damien C Croteau-Chonka Leslie A Lange Joshua D Smith Kijoung Song Jing Hua Zhao Xin Yuan Jian'an Luan Claudia Lamina Andreas Ziegler Weihua Zhang Robert Y L Zee Alan F Wright Jacqueline C M Witteman James F Wilson Gonneke Willemsen H-Erich Wichmann John B Whitfield Dawn M Waterworth Nicholas J Wareham Gérard Waeber Peter Vollenweider Benjamin F Voight Veronique Vitart Andre G Uitterlinden Manuela Uda Jaakko Tuomilehto John R Thompson Toshiko Tanaka Ida Surakka Heather M Stringham Tim D Spector Nicole Soranzo Johannes H Smit Juha Sinisalo Kaisa Silander Eric J G Sijbrands Angelo Scuteri James Scott David Schlessinger Serena Sanna Veikko Salomaa Juha Saharinen Chiara Sabatti Aimo Ruokonen Igor Rudan Lynda M Rose Robert Roberts Mark Rieder Bruce M Psaty Peter P Pramstaller Irene Pichler Markus Perola Brenda W J H Penninx Nancy L Pedersen Cristian Pattaro Alex N Parker Guillaume Pare Ben A Oostra Christopher J O'Donnell Markku S Nieminen Deborah A Nickerson Grant W Montgomery Thomas Meitinger Ruth McPherson Mark I McCarthy Wendy McArdle David Masson Nicholas G Martin Fabio Marroni Massimo Mangino Patrik K E Magnusson Gavin Lucas Robert Luben Ruth J F Loos Marja-Liisa Lokki Guillaume Lettre Claudia Langenberg Lenore J Launer Edward G Lakatta Reijo Laaksonen Kirsten O Kyvik Florian Kronenberg Inke R König Kay-Tee Khaw Jaakko Kaprio Lee M Kaplan Asa Johansson Marjo-Riitta Jarvelin A Cecile J W Janssens Erik Ingelsson Wilmar Igl G Kees Hovingh Jouke-Jan Hottenga Albert Hofman Andrew A Hicks Christian Hengstenberg Iris M Heid Caroline Hayward Aki S Havulinna Nicholas D Hastie Tamara B Harris Talin Haritunians Alistair S Hall Ulf Gyllensten Candace Guiducci Leif C Groop Elena Gonzalez Christian Gieger Nelson B Freimer Luigi Ferrucci Jeanette Erdmann Paul Elliott Kenechi G Ejebe Angela Döring Anna F Dominiczak Serkalem Demissie Panagiotis Deloukas Eco J C de Geus Ulf de Faire Gabriel Crawford Francis S Collins Yii-der I Chen Mark J Caulfield Harry Campbell Noel P Burtt Lori L Bonnycastle Dorret I Boomsma S Matthijs Boekholdt Richard N Bergman Inês Barroso Stefania Bandinelli Christie M Ballantyne Themistocles L Assimes Thomas Quertermous David Altshuler Mark Seielstad Tien Y Wong E-Shyong Tai Alan B Feranil Christopher W Kuzawa Linda S Adair Herman A Taylor Ingrid B Borecki Stacey B Gabriel James G Wilson Hilma Holm Unnur Thorsteinsdottir Vilmundur Gudnason Ronald M Krauss Karen L Mohlke Jose M Ordovas Patricia B Munroe Jaspal S Kooner Alan R Tall Robert A Hegele John J P Kastelein Eric E Schadt Jerome I Rotter Eric Boerwinkle David P Strachan Vincent Mooser Kari Stefansson Muredach P Reilly Nilesh J Samani Heribert Schunkert L Adrienne Cupples Manjinder S Sandhu Paul M Ridker Daniel J Rader Cornelia M van Duijn Leena Peltonen Gonçalo R Abecasis Michael Boehnke Sekar Kathiresan

Nature 2010 Aug;466(7307):707-13

Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.

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August 2010

Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapib.

Arterioscler Thromb Vasc Biol 2010 Jul 6;30(7):1430-8. Epub 2010 May 6.

Division of Molecular Medicine, Department of Medicine, Columbia University, 630 W 168th St, New York, NY 10032, USA.

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July 2010

ABCA1 and ABCG1 protect against oxidative stress-induced macrophage apoptosis during efferocytosis.

Circ Res 2010 Jun 29;106(12):1861-9. Epub 2010 Apr 29.

Division of Molecular Medicine, Department of Medicine, 630 W 168th St, Columbia University, New York, NY 10032, USA.

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June 2010

ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation.

Science 2010 Jun 20;328(5986):1689-93. Epub 2010 May 20.

Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY 10032, USA.

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June 2010

Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses.

Arterioscler Thromb Vasc Biol 2010 Feb 1;30(2):139-43. Epub 2009 Oct 1.

Division of Molecular Medicine, Department of Medicine, Columbia University, 630 W 168th St, New York, NY 10032, USA.

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February 2010

Increased HDL cholesterol and apoA-I in humans and mice treated with a novel SR-BI inhibitor.

Arterioscler Thromb Vasc Biol 2009 Dec 8;29(12):2054-60. Epub 2009 Oct 8.

Division of Molecular Medicine, Department of Medicine, Columbia University, New York, USA.

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December 2009

The effects of cholesterol ester transfer protein inhibition on cholesterol efflux.

Authors:
Alan R Tall

Am J Cardiol 2009 Nov;104(10 Suppl):39E-45E

Columbia University Medical Center, New York, NY 10032, USA.

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November 2009

The role of plasma lipid transfer proteins in lipoprotein metabolism and atherogenesis.

J Lipid Res 2009 Apr 20;50 Suppl:S201-6. Epub 2008 Nov 20.

Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY 10032, USA.

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April 2009

Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice.

J Clin Invest 2009 Apr 9;119(4):1029-41. Epub 2009 Mar 9.

Division of Molecular Medicine, Department of Medicine, Columbia University, 630 West 168th St., New York, New York 10032, USA.

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April 2009

Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice.

J Clin Invest 2009 Apr 16;119(4):886-98. Epub 2009 Mar 16.

Department of Medicine, Division of Molecular Medicine, Columbia University, PH 9-405, 630 W. 168th Street, New York, New York 10032, USA.

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April 2009

ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet.

J Clin Invest 2008 Nov 16;118(11):3701-13. Epub 2008 Oct 16.

Division of Molecular Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA.

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November 2008

HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis.

Cell Metab 2008 May;7(5):365-75

Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY 10032, USA.

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May 2008

ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain.

FASEB J 2008 Apr 26;22(4):1073-82. Epub 2007 Nov 26.

Department of Medicine, Columbia University, PS 8-401, 630 W. 168th St., New York, NY 10032, USA.

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April 2008

Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice.

J Clin Invest 2007 Dec;117(12):3900-8

Division of Molecular Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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December 2007