Publications by authors named "Alan P Brown"

20Publications

New Perspectives on Drug-Induced Liver Injury Risk Assessment of Acyl Glucuronides.

Chem Res Toxicol 2020 Jul 29;33(7):1551-1560. Epub 2020 Jun 29.

PK Sciences, Novartis Institutes for Biomedical Research, Novartis Campus, 4052 Basel, Switzerland.

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July 2020

Mortality Associated With Opioid Overdose: A Review of Clinical Characteristics and Health Services Received in the Year Prior to Death.

Psychiatr Serv 2019 02 24;70(2):90-96. Epub 2018 Oct 24.

Division of Addiction Psychiatry, Department of Psychiatry (all but Yarzebski), Department of Quantitative Health Sciences (Yarzebski), and Department of Radiology (DiGirolamo), University of Massachusetts Medical School, Worcester; Department of Family Medicine (Rose) and Department of Psychiatry (Shahanaghi), Boston Medical Center, Boston; MAYU of New England, New Haven, Connecticut (Romero-Gonzalez); Department of Psychology, College of the Holy Cross, Worcester (DiGirolamo); U.S. Department of Veterans Affairs Central Western Massachusetts Healthcare System, Leeds (Gonzalez).

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February 2019

Graphical display of histopathology data from toxicology studies for drug discovery and development: An industry perspective.

Regul Toxicol Pharmacol 2016 Dec 18;82:167-172. Epub 2016 Oct 18.

Integrated Nonclinical Development Solutions (INDS) Incorporated, 6111 Jackson Road, Suite 100, Ann Arbor, MI 48103, USA.

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December 2016

Interconnectivity of Disparate Nonclinical Data Silos for Drug Discovery and Development.

Ther Innov Regul Sci 2014 Jul;48(4):498-506

5 Center for Biologics Evaluation and Research, US Food and Drug Administration, Rockville, MD, USA.

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July 2014

Degradation of MSCRAMM target macromolecules in VLU slough by Lucilia sericata chymotrypsin 1 (ISP) persists in the presence of tissue gelatinase activity.

Int Wound J 2015 Aug 9;12(4):414-21. Epub 2013 Jul 9.

Immune Modulation Research Group, School of Pharmacy, Nottingham, UK.

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August 2015

Manic episode after total abdominal hysterectomy with bilateral salpingo-oophorectomy: case report.

Menopause 2012 Apr;19(4):476-8

Department of Psychiatry, University of Massachusetts School of Medicine, Worcester, MA 01605, USA.

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April 2012

Development of a model of hookworm infection exhibiting salient characteristics of human infection.

Am J Trop Med Hyg 2008 Jun;78(6):936-45

Biomedical Sciences Department, Defence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire, United Kingdom.

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June 2008

Toxicity and toxicokinetics of the cyclin-dependent kinase inhibitor AG-024322 in cynomolgus monkeys following intravenous infusion.

Cancer Chemother Pharmacol 2008 Nov 29;62(6):1091-101. Epub 2008 May 29.

Drug Safety Research and Development, Pfizer Global Research and Development, Ann Arbor, MI 48105, USA.

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November 2008

Cutaneous lesions in the rat following administration of an irreversible inhibitor of erbB receptors, including the epidermal growth factor receptor.

Toxicol Pathol 2008 Apr 8;36(3):410-9. Epub 2008 May 8.

Drug Safety Research & Development, Pfizer Global Research and Development, Ann Arbor, Michigan 48105, USA.

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April 2008

Pharmacodynamic and toxicokinetic evaluation of the novel MEK inhibitor, PD0325901, in the rat following oral and intravenous administration.

Cancer Chemother Pharmacol 2007 Apr 31;59(5):671-9. Epub 2006 Aug 31.

Drug Safety Research and Development, Pfizer Global Research and Development, 2800 Plymouth Road, Ann Arbor, MI 48105, USA.

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April 2007

Preclinical toxicity of a geldanamycin analog, 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (17-DMAG), in rats and dogs: potential clinical relevance.

Cancer Chemother Pharmacol 2005 Dec 29;56(6):637-47. Epub 2005 Jun 29.

Toxicology and Pharmacology Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Executive Plaza North, Room 8040, Rockville, MD 20852, USA.

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December 2005

Evaluation of hydrogen ion concentrations in prostates from rats and dogs using fluorescent confocal microscopy.

J Photochem Photobiol B 2005 Sep;80(3):225-34

Toxicology Research Laboratory, University of Illinois at Chicago, Chicago IL 60612-7353, USA.

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September 2005

Preclinical toxicity studies of kahalalide F, a new anticancer agent: single and multiple dosing regimens in the rat.

Cancer Chemother Pharmacol 2002 Oct 3;50(4):333-40. Epub 2002 Aug 3.

Toxicology Research Laboratory, University of Illinois at Chicago, Chicago, IL 60612, USA.

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October 2002

Na-ctl-2, a cDNA encoding a C-type lectin expressed exclusively in adult Necator americanus hookworms.

DNA Seq 2002 Feb;13(1):61-5

Division of Infectious Diseases and Immunology, Queensland Institute of Medical Research, Qld 4006, Australia.

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February 2002