Publications by authors named "Alan J Herr"

18Publications

Rate volatility and asymmetric segregation diversify mutation burden in cells with mutator alleles.

Commun Biol 2021 Jan 4;4(1):21. Epub 2021 Jan 4.

Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195-7705, USA.

View Article and Find Full Text PDF
January 2021

Normally lethal amino acid substitutions suppress an ultramutator DNA Polymerase δ variant.

Sci Rep 2017 04 18;7:46535. Epub 2017 Apr 18.

Department of Pathology, University of Washington, Seattle, Washington 98195, USA.

View Article and Find Full Text PDF
April 2017

Volatility of Mutator Phenotypes at Single Cell Resolution.

PLoS Genet 2015 Apr 13;11(4):e1005151. Epub 2015 Apr 13.

Department of Pathology, University of Washington, Seattle, Washington, United States of America.

View Article and Find Full Text PDF
April 2015

dNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase ε variants.

Proc Natl Acad Sci U S A 2015 May 31;112(19):E2457-66. Epub 2015 Mar 31.

Department of Pathology, University of Washington, Seattle, WA 98195; and

View Article and Find Full Text PDF
May 2015

DNA replication error-induced extinction of diploid yeast.

Genetics 2014 Mar 3;196(3):677-91. Epub 2014 Jan 3.

Department of Pathology, University of Washington, Seattle, Washington 98195.

View Article and Find Full Text PDF
March 2014

Emergence of DNA polymerase ε antimutators that escape error-induced extinction in yeast.

Genetics 2013 Mar 10;193(3):751-70. Epub 2013 Jan 10.

Department of Pathology, University of Washington, Seattle, WA 98195, USA.

View Article and Find Full Text PDF
March 2013

Somatic mutations in aging, cancer and neurodegeneration.

Mech Ageing Dev 2012 Apr 3;133(4):118-26. Epub 2011 Nov 3.

Department of Pathology, University of Washington School of Medicine, Seattle, WA 98195-7705, USA.

View Article and Find Full Text PDF
April 2012

Mutator suppression and escape from replication error-induced extinction in yeast.

PLoS Genet 2011 Oct 6;7(10):e1002282. Epub 2011 Oct 6.

Department of Pathology, University of Washington, Seattle, Washington, United States of America.

View Article and Find Full Text PDF
October 2011

Antimutator variants of DNA polymerases.

Crit Rev Biochem Mol Biol 2011 Dec 6;46(6):548-70. Epub 2011 Oct 6.

Department of Pathology, University of Washington, Seattle, USA.

View Article and Find Full Text PDF
December 2011

DNA replication fidelity and cancer.

Semin Cancer Biol 2010 Oct 15;20(5):281-93. Epub 2010 Oct 15.

Department of Pathology, University of Washington, Seattle, WA 98195, USA.

View Article and Find Full Text PDF
October 2010

Defective RNA processing enhances RNA silencing and influences flowering of Arabidopsis.

Proc Natl Acad Sci U S A 2006 Oct 28;103(41):14994-5001. Epub 2006 Sep 28.

Sainsbury Laboratory, John Innes Centre, Norwich NR4 7UH, United Kingdom.

View Article and Find Full Text PDF
October 2006

Pathways through the small RNA world of plants.

Authors:
Alan J Herr

FEBS Lett 2005 Oct 2;579(26):5879-88. Epub 2005 Sep 2.

Sainsbury Laboratory, John Innes Centre, Colney Lane, Norwich NR4 7UH, United Kingdom.

View Article and Find Full Text PDF
October 2005