Alan J Gow

Alan J Gow

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Alan J Gow

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Perivascular spaces in the centrum semiovale at the beginning of the 8th decade of life: effect on cognition and associations with mineral deposition.

Brain Imaging Behav 2019 Jun 27. Epub 2019 Jun 27.

Department of Neuroimaging Sciences, Centre for Clinical Brain Sciences, University of Edinburgh, 49 Little France Crescent, Chancellor's Building, Edinburgh, EH16 4SB, UK.

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http://dx.doi.org/10.1007/s11682-019-00128-1DOI Listing
June 2019

A systematic literature review and meta-analysis of real-world interventions for cognitive ageing in healthy older adults.

Ageing Res Rev 2019 Mar 29;50:110-130. Epub 2019 Jan 29.

Department of Psychology, Heriot-Watt University, Edinburgh, EH14 4AS, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.arr.2019.01.006DOI Listing
March 2019

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Authors:
Evangelos Evangelou Helen R Warren David Mosen-Ansorena Borbala Mifsud Raha Pazoki He Gao Georgios Ntritsos Niki Dimou Claudia P Cabrera Ibrahim Karaman Fu Liang Ng Marina Evangelou Katarzyna Witkowska Evan Tzanis Jacklyn N Hellwege Ayush Giri Digna R Velez Edwards Yan V Sun Kelly Cho J Michael Gaziano Peter W F Wilson Philip S Tsao Csaba P Kovesdy Tonu Esko Reedik Mägi Lili Milani Peter Almgren Thibaud Boutin Stéphanie Debette Jun Ding Franco Giulianini Elizabeth G Holliday Anne U Jackson Ruifang Li-Gao Wei-Yu Lin Jian'an Luan Massimo Mangino Christopher Oldmeadow Bram Peter Prins Yong Qian Muralidharan Sargurupremraj Nabi Shah Praveen Surendran Sébastien Thériault Niek Verweij Sara M Willems Jing-Hua Zhao Philippe Amouyel John Connell Renée de Mutsert Alex S F Doney Martin Farrall Cristina Menni Andrew D Morris Raymond Noordam Guillaume Paré Neil R Poulter Denis C Shields Alice Stanton Simon Thom Gonçalo Abecasis Najaf Amin Dan E Arking Kristin L Ayers Caterina M Barbieri Chiara Batini Joshua C Bis Tineka Blake Murielle Bochud Michael Boehnke Eric Boerwinkle Dorret I Boomsma Erwin P Bottinger Peter S Braund Marco Brumat Archie Campbell Harry Campbell Aravinda Chakravarti John C Chambers Ganesh Chauhan Marina Ciullo Massimiliano Cocca Francis Collins Heather J Cordell Gail Davies Martin H de Borst Eco J de Geus Ian J Deary Joris Deelen Fabiola Del Greco M Cumhur Yusuf Demirkale Marcus Dörr Georg B Ehret Roberto Elosua Stefan Enroth A Mesut Erzurumluoglu Teresa Ferreira Mattias Frånberg Oscar H Franco Ilaria Gandin Paolo Gasparini Vilmantas Giedraitis Christian Gieger Giorgia Girotto Anuj Goel Alan J Gow Vilmundur Gudnason Xiuqing Guo Ulf Gyllensten Anders Hamsten Tamara B Harris Sarah E Harris Catharina A Hartman Aki S Havulinna Andrew A Hicks Edith Hofer Albert Hofman Jouke-Jan Hottenga Jennifer E Huffman Shih-Jen Hwang Erik Ingelsson Alan James Rick Jansen Marjo-Riitta Jarvelin Roby Joehanes Åsa Johansson Andrew D Johnson Peter K Joshi Pekka Jousilahti J Wouter Jukema Antti Jula Mika Kähönen Sekar Kathiresan Bernard D Keavney Kay-Tee Khaw Paul Knekt Joanne Knight Ivana Kolcic Jaspal S Kooner Seppo Koskinen Kati Kristiansson Zoltan Kutalik Maris Laan Marty Larson Lenore J Launer Benjamin Lehne Terho Lehtimäki David C M Liewald Li Lin Lars Lind Cecilia M Lindgren YongMei Liu Ruth J F Loos Lorna M Lopez Yingchang Lu Leo-Pekka Lyytikäinen Anubha Mahajan Chrysovalanto Mamasoula Jaume Marrugat Jonathan Marten Yuri Milaneschi Anna Morgan Andrew P Morris Alanna C Morrison Peter J Munson Mike A Nalls Priyanka Nandakumar Christopher P Nelson Teemu Niiranen Ilja M Nolte Teresa Nutile Albertine J Oldehinkel Ben A Oostra Paul F O'Reilly Elin Org Sandosh Padmanabhan Walter Palmas Aarno Palotie Alison Pattie Brenda W J H Penninx Markus Perola Annette Peters Ozren Polasek Peter P Pramstaller Quang Tri Nguyen Olli T Raitakari Meixia Ren Rainer Rettig Kenneth Rice Paul M Ridker Janina S Ried Harriëtte Riese Samuli Ripatti Antonietta Robino Lynda M Rose Jerome I Rotter Igor Rudan Daniela Ruggiero Yasaman Saba Cinzia F Sala Veikko Salomaa Nilesh J Samani Antti-Pekka Sarin Reinhold Schmidt Helena Schmidt Nick Shrine David Siscovick Albert V Smith Harold Snieder Siim Sõber Rossella Sorice John M Starr David J Stott David P Strachan Rona J Strawbridge Johan Sundström Morris A Swertz Kent D Taylor Alexander Teumer Martin D Tobin Maciej Tomaszewski Daniela Toniolo Michela Traglia Stella Trompet Jaakko Tuomilehto Christophe Tzourio André G Uitterlinden Ahmad Vaez Peter J van der Most Cornelia M van Duijn Anne-Claire Vergnaud Germaine C Verwoert Veronique Vitart Uwe Völker Peter Vollenweider Dragana Vuckovic Hugh Watkins Sarah H Wild Gonneke Willemsen James F Wilson Alan F Wright Jie Yao Tatijana Zemunik Weihua Zhang John R Attia Adam S Butterworth Daniel I Chasman David Conen Francesco Cucca John Danesh Caroline Hayward Joanna M M Howson Markku Laakso Edward G Lakatta Claudia Langenberg Olle Melander Dennis O Mook-Kanamori Colin N A Palmer Lorenz Risch Robert A Scott Rodney J Scott Peter Sever Tim D Spector Pim van der Harst Nicholas J Wareham Eleftheria Zeggini Daniel Levy Patricia B Munroe Christopher Newton-Cheh Morris J Brown Andres Metspalu Adriana M Hung Christopher J O'Donnell Todd L Edwards Bruce M Psaty Ioanna Tzoulaki Michael R Barnes Louise V Wain Paul Elliott Mark J Caulfield

Nat Genet 2018 12;50(12):1755

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://www.nature.com/articles/s41588-018-0297-3
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http://dx.doi.org/10.1038/s41588-018-0297-3DOI Listing
December 2018

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Authors:
Evangelos Evangelou Helen R Warren David Mosen-Ansorena Borbala Mifsud Raha Pazoki He Gao Georgios Ntritsos Niki Dimou Claudia P Cabrera Ibrahim Karaman Fu Liang Ng Marina Evangelou Katarzyna Witkowska Evan Tzanis Jacklyn N Hellwege Ayush Giri Digna R Velez Edwards Yan V Sun Kelly Cho J Michael Gaziano Peter W F Wilson Philip S Tsao Csaba P Kovesdy Tonu Esko Reedik Mägi Lili Milani Peter Almgren Thibaud Boutin Stéphanie Debette Jun Ding Franco Giulianini Elizabeth G Holliday Anne U Jackson Ruifang Li-Gao Wei-Yu Lin Jian'an Luan Massimo Mangino Christopher Oldmeadow Bram Peter Prins Yong Qian Muralidharan Sargurupremraj Nabi Shah Praveen Surendran Sébastien Thériault Niek Verweij Sara M Willems Jing-Hua Zhao Philippe Amouyel John Connell Renée de Mutsert Alex S F Doney Martin Farrall Cristina Menni Andrew D Morris Raymond Noordam Guillaume Paré Neil R Poulter Denis C Shields Alice Stanton Simon Thom Gonçalo Abecasis Najaf Amin Dan E Arking Kristin L Ayers Caterina M Barbieri Chiara Batini Joshua C Bis Tineka Blake Murielle Bochud Michael Boehnke Eric Boerwinkle Dorret I Boomsma Erwin P Bottinger Peter S Braund Marco Brumat Archie Campbell Harry Campbell Aravinda Chakravarti John C Chambers Ganesh Chauhan Marina Ciullo Massimiliano Cocca Francis Collins Heather J Cordell Gail Davies Martin H de Borst Eco J de Geus Ian J Deary Joris Deelen Fabiola Del Greco M Cumhur Yusuf Demirkale Marcus Dörr Georg B Ehret Roberto Elosua Stefan Enroth A Mesut Erzurumluoglu Teresa Ferreira Mattias Frånberg Oscar H Franco Ilaria Gandin Paolo Gasparini Vilmantas Giedraitis Christian Gieger Giorgia Girotto Anuj Goel Alan J Gow Vilmundur Gudnason Xiuqing Guo Ulf Gyllensten Anders Hamsten Tamara B Harris Sarah E Harris Catharina A Hartman Aki S Havulinna Andrew A Hicks Edith Hofer Albert Hofman Jouke-Jan Hottenga Jennifer E Huffman Shih-Jen Hwang Erik Ingelsson Alan James Rick Jansen Marjo-Riitta Jarvelin Roby Joehanes Åsa Johansson Andrew D Johnson Peter K Joshi Pekka Jousilahti J Wouter Jukema Antti Jula Mika Kähönen Sekar Kathiresan Bernard D Keavney Kay-Tee Khaw Paul Knekt Joanne Knight Ivana Kolcic Jaspal S Kooner Seppo Koskinen Kati Kristiansson Zoltan Kutalik Maris Laan Marty Larson Lenore J Launer Benjamin Lehne Terho Lehtimäki David C M Liewald Li Lin Lars Lind Cecilia M Lindgren YongMei Liu Ruth J F Loos Lorna M Lopez Yingchang Lu Leo-Pekka Lyytikäinen Anubha Mahajan Chrysovalanto Mamasoula Jaume Marrugat Jonathan Marten Yuri Milaneschi Anna Morgan Andrew P Morris Alanna C Morrison Peter J Munson Mike A Nalls Priyanka Nandakumar Christopher P Nelson Teemu Niiranen Ilja M Nolte Teresa Nutile Albertine J Oldehinkel Ben A Oostra Paul F O'Reilly Elin Org Sandosh Padmanabhan Walter Palmas Aarno Palotie Alison Pattie Brenda W J H Penninx Markus Perola Annette Peters Ozren Polasek Peter P Pramstaller Quang Tri Nguyen Olli T Raitakari Meixia Ren Rainer Rettig Kenneth Rice Paul M Ridker Janina S Ried Harriëtte Riese Samuli Ripatti Antonietta Robino Lynda M Rose Jerome I Rotter Igor Rudan Daniela Ruggiero Yasaman Saba Cinzia F Sala Veikko Salomaa Nilesh J Samani Antti-Pekka Sarin Reinhold Schmidt Helena Schmidt Nick Shrine David Siscovick Albert V Smith Harold Snieder Siim Sõber Rossella Sorice John M Starr David J Stott David P Strachan Rona J Strawbridge Johan Sundström Morris A Swertz Kent D Taylor Alexander Teumer Martin D Tobin Maciej Tomaszewski Daniela Toniolo Michela Traglia Stella Trompet Jaakko Tuomilehto Christophe Tzourio André G Uitterlinden Ahmad Vaez Peter J van der Most Cornelia M van Duijn Anne-Claire Vergnaud Germaine C Verwoert Veronique Vitart Uwe Völker Peter Vollenweider Dragana Vuckovic Hugh Watkins Sarah H Wild Gonneke Willemsen James F Wilson Alan F Wright Jie Yao Tatijana Zemunik Weihua Zhang John R Attia Adam S Butterworth Daniel I Chasman David Conen Francesco Cucca John Danesh Caroline Hayward Joanna M M Howson Markku Laakso Edward G Lakatta Claudia Langenberg Olle Melander Dennis O Mook-Kanamori Colin N A Palmer Lorenz Risch Robert A Scott Rodney J Scott Peter Sever Tim D Spector Pim van der Harst Nicholas J Wareham Eleftheria Zeggini Daniel Levy Patricia B Munroe Christopher Newton-Cheh Morris J Brown Andres Metspalu Adriana M Hung Christopher J O'Donnell Todd L Edwards Bruce M Psaty Ioanna Tzoulaki Michael R Barnes Louise V Wain Paul Elliott Mark J Caulfield

Nat Genet 2018 10 17;50(10):1412-1425. Epub 2018 Sep 17.

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1038/s41588-018-0205-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284793PMC
October 2018

The Influence of Dyslexia Candidate Genes on Reading Skill in Old Age.

Behav Genet 2018 09 29;48(5):351-360. Epub 2018 Jun 29.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1007/s10519-018-9913-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097729PMC
September 2018

Older Adults Experiences of Learning to Use Tablet Computers: A Mixed Methods Study.

Front Psychol 2018 3;9:1631. Epub 2018 Sep 3.

Department of Psychology, School of Social Sciences, Heriot-Watt University, Edinburgh, United Kingdom.

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http://dx.doi.org/10.3389/fpsyg.2018.01631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130193PMC
September 2018

People's Beliefs and Expectations About How Cognitive Skills Change with Age: Evidence From a U.K.-Wide Aging Survey.

Am J Geriatr Psychiatry 2018 07 4;26(7):797-805. Epub 2018 Apr 4.

Department of Psychology, School of Social Sciences, Heriot-Watt University, Edinburgh, United Kingdom; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jagp.2018.03.016DOI Listing
July 2018

Older Adults Perceptions of Technology and Barriers to Interacting with Tablet Computers: A Focus Group Study.

Front Psychol 2017 Oct;8:1687

Department of Psychology, School of Social Sciences, Heriot-Watt University, Edinburgh, United Kingdom.

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http://dx.doi.org/10.3389/fpsyg.2017.01687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649151PMC
October 2017

A Tablet for Healthy Ageing: The Effect of a Tablet Computer Training Intervention on Cognitive Abilities in Older Adults.

Am J Geriatr Psychiatry 2017 Aug 5;25(8):841-851. Epub 2016 Dec 5.

Department of Psychology, School of Social Sciences, Heriot-Watt University, Edinburgh, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jagp.2016.11.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444526PMC
August 2017

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.

Authors:
Louise V Wain Ahmad Vaez Rick Jansen Roby Joehanes Peter J van der Most A Mesut Erzurumluoglu Paul F O'Reilly Claudia P Cabrera Helen R Warren Lynda M Rose Germaine C Verwoert Jouke-Jan Hottenga Rona J Strawbridge Tonu Esko Dan E Arking Shih-Jen Hwang Xiuqing Guo Zoltan Kutalik Stella Trompet Nick Shrine Alexander Teumer Janina S Ried Joshua C Bis Albert V Smith Najaf Amin Ilja M Nolte Leo-Pekka Lyytikäinen Anubha Mahajan Nicholas J Wareham Edith Hofer Peter K Joshi Kati Kristiansson Michela Traglia Aki S Havulinna Anuj Goel Mike A Nalls Siim Sõber Dragana Vuckovic Jian'an Luan Fabiola Del Greco M Kristin L Ayers Jaume Marrugat Daniela Ruggiero Lorna M Lopez Teemu Niiranen Stefan Enroth Anne U Jackson Christopher P Nelson Jennifer E Huffman Weihua Zhang Jonathan Marten Ilaria Gandin Sarah E Harris Tatijana Zemunik Yingchang Lu Evangelos Evangelou Nabi Shah Martin H de Borst Massimo Mangino Bram P Prins Archie Campbell Ruifang Li-Gao Ganesh Chauhan Christopher Oldmeadow Gonçalo Abecasis Maryam Abedi Caterina M Barbieri Michael R Barnes Chiara Batini John Beilby Tineka Blake Michael Boehnke Erwin P Bottinger Peter S Braund Morris Brown Marco Brumat Harry Campbell John C Chambers Massimiliano Cocca Francis Collins John Connell Heather J Cordell Jeffrey J Damman Gail Davies Eco J de Geus Renée de Mutsert Joris Deelen Yusuf Demirkale Alex S F Doney Marcus Dörr Martin Farrall Teresa Ferreira Mattias Frånberg He Gao Vilmantas Giedraitis Christian Gieger Franco Giulianini Alan J Gow Anders Hamsten Tamara B Harris Albert Hofman Elizabeth G Holliday Jennie Hui Marjo-Riitta Jarvelin Åsa Johansson Andrew D Johnson Pekka Jousilahti Antti Jula Mika Kähönen Sekar Kathiresan Kay-Tee Khaw Ivana Kolcic Seppo Koskinen Claudia Langenberg Marty Larson Lenore J Launer Benjamin Lehne David C M Liewald Li Lin Lars Lind François Mach Chrysovalanto Mamasoula Cristina Menni Borbala Mifsud Yuri Milaneschi Anna Morgan Andrew D Morris Alanna C Morrison Peter J Munson Priyanka Nandakumar Quang Tri Nguyen Teresa Nutile Albertine J Oldehinkel Ben A Oostra Elin Org Sandosh Padmanabhan Aarno Palotie Guillaume Paré Alison Pattie Brenda W J H Penninx Neil Poulter Peter P Pramstaller Olli T Raitakari Meixia Ren Kenneth Rice Paul M Ridker Harriëtte Riese Samuli Ripatti Antonietta Robino Jerome I Rotter Igor Rudan Yasaman Saba Aude Saint Pierre Cinzia F Sala Antti-Pekka Sarin Reinhold Schmidt Rodney Scott Marc A Seelen Denis C Shields David Siscovick Rossella Sorice Alice Stanton David J Stott Johan Sundström Morris Swertz Kent D Taylor Simon Thom Ioanna Tzoulaki Christophe Tzourio André G Uitterlinden Uwe Völker Peter Vollenweider Sarah Wild Gonneke Willemsen Alan F Wright Jie Yao Sébastien Thériault David Conen John Attia Peter Sever Stéphanie Debette Dennis O Mook-Kanamori Eleftheria Zeggini Tim D Spector Pim van der Harst Colin N A Palmer Anne-Claire Vergnaud Ruth J F Loos Ozren Polasek John M Starr Giorgia Girotto Caroline Hayward Jaspal S Kooner Cecila M Lindgren Veronique Vitart Nilesh J Samani Jaakko Tuomilehto Ulf Gyllensten Paul Knekt Ian J Deary Marina Ciullo Roberto Elosua Bernard D Keavney Andrew A Hicks Robert A Scott Paolo Gasparini Maris Laan YongMei Liu Hugh Watkins Catharina A Hartman Veikko Salomaa Daniela Toniolo Markus Perola James F Wilson Helena Schmidt Jing Hua Zhao Terho Lehtimäki Cornelia M van Duijn Vilmundur Gudnason Bruce M Psaty Annette Peters Rainer Rettig Alan James J Wouter Jukema David P Strachan Walter Palmas Andres Metspalu Erik Ingelsson Dorret I Boomsma Oscar H Franco Murielle Bochud Christopher Newton-Cheh Patricia B Munroe Paul Elliott Daniel I Chasman Aravinda Chakravarti Joanne Knight Andrew P Morris Daniel Levy Martin D Tobin Harold Snieder Mark J Caulfield Georg B Ehret

Hypertension 2017 Jul 24. Epub 2017 Jul 24.

From the Department of Health Sciences (L.V.W., A.M.E., N. Shrine, C.B., T.B., M.D.T.), and Department of Cardiovascular Sciences and NIHR Leicester Biomedical Research Centre (C.P.N., P.S.B., N.J.S.), University of Leicester, United Kingdom; Department of Epidemiology (A.V., P.J.v.d.M., I.M.N., H. Snieder), Division of Nephrology, Department of Internal Medicine (M.H.d.B., M.A.S.), Interdisciplinary Center Psychopathology and Emotion Regulation (IPCE) (A.J.O., H.R., C.A.H.), Department of Genetics, (M.S.), and Department of Cardiology (P.v.d.H.), University of Groningen, University Medical Center Groningen, The Netherlands; Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Iran (A.V.); Department of Psychiatry, VU University Medical Center, Neuroscience Campus Amsterdam, The Netherlands (R. Jansen); Hebrew SeniorLife, Harvard Medical School, Boston, MA (R. Joehanes); National Heart, Lung and Blood Institute's Framingham Heart Study, MA (R. Joehanes, A.D.J., M. Larson); Institute of Psychiatry, Psychology and Neuroscience (P.F.O.), and Department of Twin Research and Genetic Epidemiology (M.M., C. Menni, T.D.S.), King's College London, United Kingdom; Clinical Pharmacology, William Harvey Research Institute (C.P.C., H.R.W., M.R.B., M. Brown, B.M., M.R., P.B.M., M.J.C.) and NIHR Barts Cardiovascular Biomedical Research Unit (C.P.C., H.R.W., M.R.B., M. Brown, P.B.M., M.J.C.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA (L.M.R., F.G., P.M.R., D.I.C.); Department of Epidemiology (G.C.V., A. Hofman, A.G.U., O.H.F.), Genetic Epidemiology Unit, Department of Epidemiology (N.A., B.A.O., C.M.v.D.), and Department of Internal Medicine (A.G.U.), Erasmus MC, Rotterdam, The Netherlands; Department of Biological Psychology, Vrije Universiteit, Amsterdam, EMGO+ Institute, VU University Medical Center, The Netherlands (J.-J.H., E.J.d.G., G.W., D.I.B.); Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden (R.J.S., M. Frånberg, A. Hamsten); Centre for Molecular Medicine, Karolinska Universitetsjukhuset, Solna, Sweden (R.J.S., M. Frånberg, A. Hamsten); Estonian Genome Center (T.E., E.O., A. Metspalu), Institute of Biomedicine and Translational Medicine (S.S., M. Laan), and Estonian Genome Center (M.P.), University of Tartu, Estonia; Divisions of Endocrinology/Children's Hospital, Boston, MA (T.E.); Broad Institute of Harvard and MIT, Cambridge, MA (T.E., C.M.L., C.N.-C.); Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (D.E.A., P.N., A. Chakravarti, G.B.E.); The Population Science Branch, Division of Intramural Research, National Heart Lung and Blood Institute (S.-J.H., D.L.), Laboratory of Neurogenetics, National Institute on Aging (M.A.N.), Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute (F.C.), and Center for Information Technology (Y.D., P.J.M., Q.T.N.), National Institutes of Health, Bethesda, MD; The Framingham Heart Study, Framingham, MA (S.-J.H., D.L.); The Institute for Translational Genomics and Population Sciences, Department of Pediatrics (X.G., J.Y.), and The Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine (J.I.R.), LABioMed at Harbor-UCLA Medical Center, Torrance, CA; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland (Z.K., M. Bochud); Swiss Institute of Bioinformatics, Lausanne, Switzerland (Z.K.); Department of Cardiology (S. Trompet, J.W.J.) Department of Gerontology and Geriatrics (S. Trompet), Department of Clinical Epidemiology (R.L.-G., R.d.M., D.O.M.-K.), Department of Molecular Epidemiology (J.D.), and Department of Public Health and Primary Care (D.O.M.-K.), Leiden University Medical Center, The Netherlands; Institute for Community Medicine (A.T.), Department of Internal Medicine B (M.D.), and Interfaculty Institute for Genetics and Functional Genomics (U.V.), University Medicine Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Germany (A.T., M.D., U.V.); Institute of Epidemiology II, Helmholtz Zentrum München, Neuherberg, Germany (J.S.R., A. Peters); Cardiovascular Health Research Unit, Department of Medicine (J.C.B., B.M.P.) and Departments of Biostatistics (K.R.), Epidemiology (B.M.P.), and Health Services (B.M.P.), University of Washington, Seattle; Icelandic Heart Association, Kopavogur, Iceland (A.V.S., V. Gudnason); Faculty of Medicine, University of Iceland, Reykjavik, Iceland (A.V.S., V. Gudnason); Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland (L.-P.L., T.L.); Department of Clinical Chemistry, Faculty of Medicine and Life Sciences, University of Tampere, Finland (L.-P.L., T.L.); Wellcome Trust Centre for Human Genetics (A. Mahajan, A.G., M. Farrall, T.F., C.M.L., H.W., A.P.M.), and Division of Cardiovascular Medicine, Radcliffe Department of Medicine (A.G., M. Farrall, H.W.), University of Oxford, United Kingdom; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, United Kingdom (N.J.W., J.L., C.L., R.J.F.L., R.A.S., J.H.Z.); Clinical Division of Neurogeriatrics, Department of Neurology (E.H., R. Schmidt), Institute of Medical Informatics, Statistics and Documentation (E.H.), and Department of Neurology (H. Schmidt), Medical University Graz, Austria; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics (P.K.J., H.C., I.R., S.W., J.F.W.), Centre for Cognitive Ageing and Cognitive Epidemiology (L.M.L., S.E.H., G.D., A.J.G., D.C.M.L., J.M.S., I.J.D.), Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine (A. Campbell), Generation Scotland, Centre for Genomic and Experimental Medicine (A. Campbell, S.P., C.H.), Department of Psychology (G.D., D.C.M.L., A. Pattie, I.J.D.), Alzheimer Scotland Dementia Research Centre (J.M.S.), and Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine (C.H.), University of Edinburgh, Scotland, United Kingdom; Department of Health (K.K., A.S.H., T. Niiranen, P.J., A.J., S. Koskinen, P.K., V.S., M.P.), and Chronic Disease Prevention Unit (J.T.), National Institute for Health and Welfare (THL), Helsinki, Finland; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy (M.T., C.M.B., C.F.S., D.T.); Data Tecnica International, Glen Echo, MD (M.A.N.); Medical Genetics, IRCCS-Burlo Garofolo Children Hospital, Trieste, Italy (D.V., G.G., P.G.); Department of Medical, Surgical and Health Sciences, University of Trieste, Italy (D.V., I.G., M. Brumat, M. Cocca, A. Morgan, G.G., P.G.); Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, Italy (F.D.G.M., P.P.P., A.S.P., A.A.H.); Department of Genetics and Genomic Sciences (K.L.A.), The Charles Bronfman Institute for Personalized Medicine (Y.L., E.P.B., R.J.F.L.), and Mindich Child health Development Institute (R.J.F.L.), Icahn School of Medicine at Mount Sinai, New York; Cardiovascular Epidemiology and Genetics, IMIM, and CIBERCV, Barcelona, Spain (J. Marrugat, R.E.); Institute of Genetics and Biophysics A. Buzzati-Traverso, CNR, Napoli, Italy (D.R., T. Nutile, R. Sorice, M. Ciullo); Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin (L.M.L.); UCD Conway Institute, Centre for Proteome Research (L.M.L.), and School of Medicine, Conway Institute (D.C.S.), University College Dublin, Belfield, Ireland; Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Sweden (S.E., Å. Johansson, U.G.); Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor (A.U.J., M. Boehnke); NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester United Kingdom (C.P.N., P.S.B., N.J.S.); MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine (J.E.H., V.V., J. Marten, A.F.W., J.F.W.), and Medical Genetics Section, Centre for Genomic and Experimental Medicine and MRC Institute of Genetics and Molecular Medicine (S.E.H.), University of Edinburgh, Western General Hospital, Scotland, United Kingdom; Department of Epidemiology and Biostatistics, School of Public Health (W.Z., E.E., J.C.C., H.G., B.L., I.T., A.-C.V.), MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health (M.-R.J., P.E.), School of Public Health (N.P.), International Centre for Circulatory Health (S. Thom), and National Heart and Lung Institute (P.S.), Imperial College London, United Kingdom; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Southall, United Kingdom (W.Z., J.C.C., J.S.K.); Department of Medical Biology, Faculty of Medicine, University of Split, Croatia (T.Z.); Department of Hygiene and Epidemiology, University of Ioannina Medical School, Greece (E.E.); Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Scotland, United Kingdom (N. Shah, A.S.F.D., C.N.A.P.); Department of Pharmacy, COMSATS Institute of Information Technology, Abbottabad, Pakistan (N. Shah); National Institute for Health Research Biomedical Research Centre, London, United Kingdom (M.M.); Department of Human Genetics, Wellcome Trust Sanger Institute, United Kingdom (B.P.P., E.Z.); INSERM U 1219, Bordeaux Population Health Center, France (G.C., C.T., S.D.); Bordeaux University, France (G.C., C.T., S.D.); Hunter Medical Research Institute, New Lambton, NSW, Australia (C.O., E.G.H., R. Scott, J.A.); Center for Statistical Genetics, Department of Biostatistics, Ann Arbor, MI (G.A.); Department of Genetics and Molecular Biology, Isfahan University of Medical Sciences, Iran (M.A.); Busselton Population Medical Research Institute, Western Australia (J.B., J.H.); PathWest Laboratory Medicine of Western Australia, Nedlands (J.B., J.H.); School of Pathology and Laboratory Medicine (J.B., J.H.), School of Population and Global Health (J.H.), and School of Medicine and Pharmacology (A. James), The University of Western Australia, Nedlands; Imperial College Healthcare NHS Trust, London, United Kingdom (J.C.C., J.S.K.); University of Dundee, Ninewells Hospital & Medical School, United Kingdom (J.C.); Institute of Genetic Medicine (H.J.C.), and Institute of Health and Society (C. Mamasoula), Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Pathology, Amsterdam Medical Center, The Netherlands (J.J.D.); Department of Numerical Analysis and Computer Science, Stockholm University, Sweden (M. Frånberg); Department of Public Health and Caring Sciences, Geriatrics, Uppsala, Sweden (V. Giedraitis); Helmholtz Zentrum Muenchen, Deutsches Forschungszentrum fuer Gesundheit und Umwelt (GmbH), Neuherberg, Germany (C.G.); Department of Psychology, School of Social Sciences, Heriot-Watt University, Edinburgh, United Kingdom (A.J.G.); Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging (T.B.H., L.J.L.); Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA (A. Hofman); Center For Life-Course Health Research (M.-R.J.), and Biocenter Oulu (M.-R.J.), University of Oulu, Finland; Unit of Primary Care, Oulu University Hospital, Finland (M.-R.J.); National Heart, Lung and Blood Institute, Cardiovascular Epidemiology and Human Genomics Branch, Bethesda, MD (A.D.J.); Department of Clinical Physiology, Tampere University Hospital, Finland (M.K.); Department of Clinical Physiology, Faculty of Medicine and Life Sciences, University of Tampere, Finland (M.K.); Cardiovascular Research Center (S. Kathiresan, C.N.-C.); Center for Human Genetics (S. Kathiresan), and Center for Human Genetic Research (C.N.-C.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (S. Kathiresan, C.N.-C.); Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, United Kingdom (K.-T.K.); Department of Public Health, Faculty of Medicine, University of Split, Croatia (I.K., O.P.); Cardiology, Department of Specialties of Medicine, Geneva University Hospital, Switzerland (L. Lin, F.M., G.B.E.); Department of Medical Sciences, Cardiovascular Epidemiology (L. Lind, J.S.), and Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory (E.I.), Uppsala University, Sweden; Department of Psychiatry, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands (Y.M., B.W.J.H.P.); School of Molecular, Genetic and Population Health Sciences, University of Edinburgh, Medical School, Teviot Place, Scotland, United Kingdom (A.D.M.); Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston (A.C.M.); British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences (S.P.), and Institute of Cardiovascular and Medical Sciences, Faculty of Medicine (D.J.S.), University of Glasgow, United Kingdom; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Finland (A. Palotie, S.R., A.-P.S., M.P.); Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada (G.P., S. Thériault); Department of Neurology, General Central Hospital, Bolzano, Italy (P.P.P.); Department of Neurology, University of Lübeck, Germany (P.P.P.); Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Finland (O.T.R.); Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Finland (O.T.R.); Department of Cardiology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China (M.R.); Harvard Medical School, Boston, MA (P.M.R., D.I.C.); Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy (A.R.); Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Austria (Y.S., H. Schmidt); INSERM U1078, Etablissement Français du Sang, Brest Cedex, France (A.S.P.); Faculty of Health, University of Newcastle, Callaghan, NSW, Australia (R. Scott, J.A.); John Hunter Hospital, New Lambton, NSW, Australia (R. Scott, J.A.); The New York Academy of Medicine, New York (D.S.); IRCCS Neuromed, Pozzilli, Isernia, Italy (R. Sorice, M. Ciullo); Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin 2, Ireland (A.S.); Institute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA (K.D.T.); Division of Genetic Outcomes, Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA (K.D.T.); Department of Public Health (C.T.), and Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Internal Medicine, Lausanne University Hospital, CHUV, Switzerland (P.V.); Population Health Research Institute, McMaster University, Hamilton Ontario, Canada (D.C.); National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, United Kingdom (J.S.K.); Dasman Diabetes Institute, Kuwait (J.T.); Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia (J.T.); Department of Neurosciences and Preventive Medicine, Danube-University Krems, Austria (J.T.); Division of Cardiovascular Sciences, The University of Manchester and Central Manchester University Hospitals NHS Foundation Trust, United Kingdom (B.D.K.); Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem (Y.M.L.); Kaiser Permanent Washington Health Research Institute, Seattle, WA (B.M.P.); Institute of Physiology, University Medicine Greifswald, Karlsburg, Germany (R.R); Department of Pulmonary Physiology and Sleep, Sir Charles Gairdner Hospital, Nedlands, Western Australia (A. James); Population Health Research Institute, St George's, University of London, United Kingdom (D.P.S.); Department of Medicine, Columbia University Medical Center, New York (W.P.); Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, CA (E.I.); Data Science Institute and Lancaster Medical School, Lancaster University, United Kingdom (J.K.); and Department of Biostatistics, University of Liverpool, United Kingdom (A.P.M.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783787PMC
July 2017

Hippocampal morphology and cognitive functions in community-dwelling older people: the Lothian Birth Cohort 1936.

Neurobiol Aging 2017 04 21;52:1-11. Epub 2016 Dec 21.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK; Department of Psychology, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364373PMC
April 2017

Lifecourse Activity Participation From Early, Mid, and Later Adulthood as Determinants of Cognitive Aging: The Lothian Birth Cohort 1921.

J Gerontol B Psychol Sci Soc Sci 2017 Jan 7;72(1):25-37. Epub 2016 Oct 7.

Centre for Cognitive Ageing and Cognitive Epidemiology and.

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http://dx.doi.org/10.1093/geronb/gbw124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156497PMC
January 2017

Social resources and cognitive ageing across 30 years: the Glostrup 1914 Cohort.

Age Ageing 2016 07 28;45(4):480-6. Epub 2016 Apr 28.

Center for Healthy Aging, University of Copenhagen, Copenhagen, Denmark Unit of Medical Psychology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1093/ageing/afw070DOI Listing
July 2016

3D shape analysis of the brain's third ventricle using a midplane encoded symmetric template model.

Comput Methods Programs Biomed 2016 Jun 28;129:51-62. Epub 2016 Feb 28.

School of Computing, Korea Advanced Institute of Science and Technology, Daejeon, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.cmpb.2016.02.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841787PMC
June 2016

Associations between urban greenspace and health-related quality of life in children.

Prev Med Rep 2016 Jun 3;3:211-21. Epub 2016 Feb 3.

Department of Psychology, School of Life Sciences, Heriot-Watt University, Edinburgh EH14 4AS, UK.

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http://dx.doi.org/10.1016/j.pmedr.2016.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929180PMC
June 2016

Modulation of genetic associations with serum urate levels by body-mass-index in humans.

Authors:
Jennifer E Huffman Eva Albrecht Alexander Teumer Massimo Mangino Karen Kapur Toby Johnson Zoltán Kutalik Nicola Pirastu Giorgio Pistis Lorna M Lopez Toomas Haller Perttu Salo Anuj Goel Man Li Toshiko Tanaka Abbas Dehghan Daniela Ruggiero Giovanni Malerba Albert V Smith Ilja M Nolte Laura Portas Amanda Phipps-Green Lora Boteva Pau Navarro Asa Johansson Andrew A Hicks Ozren Polasek Tõnu Esko John F Peden Sarah E Harris Federico Murgia Sarah H Wild Albert Tenesa Adrienne Tin Evelin Mihailov Anne Grotevendt Gauti K Gislason Josef Coresh Pio D'Adamo Sheila Ulivi Peter Vollenweider Gerard Waeber Susan Campbell Ivana Kolcic Krista Fisher Margus Viigimaa Jeffrey E Metter Corrado Masciullo Elisabetta Trabetti Cristina Bombieri Rossella Sorice Angela Döring Eva Reischl Konstantin Strauch Albert Hofman Andre G Uitterlinden Melanie Waldenberger H-Erich Wichmann Gail Davies Alan J Gow Nicola Dalbeth Lisa Stamp Johannes H Smit Mirna Kirin Ramaiah Nagaraja Matthias Nauck Claudia Schurmann Kathrin Budde Susan M Farrington Evropi Theodoratou Antti Jula Veikko Salomaa Cinzia Sala Christian Hengstenberg Michel Burnier Reedik Mägi Norman Klopp Stefan Kloiber Sabine Schipf Samuli Ripatti Stefano Cabras Nicole Soranzo Georg Homuth Teresa Nutile Patricia B Munroe Nicholas Hastie Harry Campbell Igor Rudan Claudia Cabrera Chris Haley Oscar H Franco Tony R Merriman Vilmundur Gudnason Mario Pirastu Brenda W Penninx Harold Snieder Andres Metspalu Marina Ciullo Peter P Pramstaller Cornelia M van Duijn Luigi Ferrucci Giovanni Gambaro Ian J Deary Malcolm G Dunlop James F Wilson Paolo Gasparini Ulf Gyllensten Tim D Spector Alan F Wright Caroline Hayward Hugh Watkins Markus Perola Murielle Bochud W H Linda Kao Mark Caulfield Daniela Toniolo Henry Völzke Christian Gieger Anna Köttgen Veronique Vitart

PLoS One 2015 26;10(3):e0119752. Epub 2015 Mar 26.

Medical Research Council (MRC) Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Edinburgh, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374966PMC
March 2016

Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921.

Mech Ageing Dev 2016 Mar 10;154:43-8. Epub 2016 Feb 10.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK; Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK.

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http://dx.doi.org/10.1016/j.mad.2016.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798845PMC
March 2016

Sitting Time, Fidgeting, and All-Cause Mortality in the UK Women's Cohort Study.

Am J Prev Med 2016 Feb 23;50(2):154-60. Epub 2015 Sep 23.

Nutritional Epidemiology Group, School of Food Science and Nutrition, University of Leeds, Leeds, United Kingdom;

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http://dx.doi.org/10.1016/j.amepre.2015.06.025DOI Listing
February 2016

Total MRI load of cerebral small vessel disease and cognitive ability in older people.

Neurobiol Aging 2015 Oct 26;36(10):2806-11. Epub 2015 Jun 26.

Brain Research Imaging Centre, Department of Clinical Neurosciences, University of Edinburgh, Edinburgh, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.06.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706154PMC
October 2015

Brain iron deposits and lifespan cognitive ability.

Age (Dordr) 2015 Oct 17;37(5):100. Epub 2015 Sep 17.

Department of Neuroimaging Sciences, Centre for Clinical Brain Sciences, University of Edinburgh, 49 Little France Crescent, Chancellor's Building, Edinburgh, EH16 4SB, UK.

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http://dx.doi.org/10.1007/s11357-015-9837-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005839PMC
October 2015

Examining associations between sexual behaviours and quality of life in older adults.

Age Ageing 2015 Sep 14;44(5):823-8. Epub 2015 Jul 14.

Department of Psychology, Heriot-Watt University, Edinburgh, UK.

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http://dx.doi.org/10.1093/ageing/afv083DOI Listing
September 2015

Disentangling Wording and Substantive Factors in the Spiritual Well-Being Scale.

Psycholog Relig Spiritual 2015 May 24;7(2):120-129. Epub 2014 Nov 24.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh.

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http://dx.doi.org/10.1037/a0038001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563774PMC
May 2015

Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.

Authors:
Stéphanie Debette Carla A Ibrahim Verbaas Jan Bressler Maaike Schuur Albert Smith Joshua C Bis Gail Davies Christiane Wolf Vilmundur Gudnason Lori B Chibnik Qiong Yang Anita L deStefano Dominique J F de Quervain Velandai Srikanth Jari Lahti Hans J Grabe Jennifer A Smith Lutz Priebe Lei Yu Nazanin Karbalai Caroline Hayward James F Wilson Harry Campbell Katja Petrovic Myriam Fornage Ganesh Chauhan Robin Yeo Ruth Boxall James Becker Oliver Stegle Karen A Mather Vincent Chouraki Qi Sun Lynda M Rose Susan Resnick Christopher Oldmeadow Mirna Kirin Alan F Wright Maria K Jonsdottir Rhoda Au Albert Becker Najaf Amin Mike A Nalls Stephen T Turner Sharon L R Kardia Ben Oostra Gwen Windham Laura H Coker Wei Zhao David S Knopman Gerardo Heiss Michael E Griswold Rebecca F Gottesman Veronique Vitart Nicholas D Hastie Lina Zgaga Igor Rudan Ozren Polasek Elizabeth G Holliday Peter Schofield Seung Hoan Choi Toshiko Tanaka Yang An Rodney T Perry Richard E Kennedy Michèle M Sale Jing Wang Virginia G Wadley David C Liewald Paul M Ridker Alan J Gow Alison Pattie John M Starr David Porteous Xuan Liu Russell Thomson Nicola J Armstrong Gudny Eiriksdottir Arezoo A Assareh Nicole A Kochan Elisabeth Widen Aarno Palotie Yi-Chen Hsieh Johan G Eriksson Christian Vogler John C van Swieten Joshua M Shulman Alexa Beiser Jerome Rotter Carsten O Schmidt Wolfgang Hoffmann Markus M Nöthen Luigi Ferrucci John Attia Andre G Uitterlinden Philippe Amouyel Jean-François Dartigues Hélène Amieva Katri Räikkönen Melissa Garcia Philip A Wolf Albert Hofman W T Longstreth Bruce M Psaty Eric Boerwinkle Philip L DeJager Perminder S Sachdev Reinhold Schmidt Monique M B Breteler Alexander Teumer Oscar L Lopez Sven Cichon Daniel I Chasman Francine Grodstein Bertram Müller-Myhsok Christophe Tzourio Andreas Papassotiropoulos David A Bennett M Arfan Ikram Ian J Deary Cornelia M van Duijn Lenore Launer Annette L Fitzpatrick Sudha Seshadri Thomas H Mosley

Biol Psychiatry 2015 Apr 25;77(8):749-63. Epub 2014 Nov 25.

Department of Medicine and Neurology, University of Mississippi Medical Center, Jackson, Mississippi.

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http://dx.doi.org/10.1016/j.biopsych.2014.08.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513651PMC
April 2015

Association of allostatic load with brain structure and cognitive ability in later life.

Neurobiol Aging 2015 Mar 22;36(3):1390-9. Epub 2014 Dec 22.

Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK; Department of Psychology, The University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.12.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353502PMC
March 2015

White matter hyperintensities and normal-appearing white matter integrity in the aging brain.

Neurobiol Aging 2015 Feb 13;36(2):909-18. Epub 2014 Oct 13.

Brain Research Imaging Centre, Neuroimaging Sciences, University of Edinburgh, Edinburgh, UK; Scottish Imaging Network: A Platform for Scientific Excellence (SINAPSE) Collaboration, Edinburgh, UK; Centre for Cognitive Ageing and Cognitive Epidemiology (CCACE), University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.07.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321830PMC
February 2015

Beyond a bigger brain: Multivariable structural brain imaging and intelligence.

Intelligence 2015 Jul-Aug;51:47-56

Department of Psychology, The University of Edinburgh, United Kingdom ; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, United Kingdom.

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http://dx.doi.org/10.1016/j.intell.2015.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518535PMC
January 2015

Occupational complexity and lifetime cognitive abilities.

Neurology 2014 Dec 19;83(24):2285-91. Epub 2014 Nov 19.

From the Department of Psychology (E.L.S., I.J.D.), and Centre for Cognitive Ageing and Cognitive Epidemiology (A.J.G., I.J.D.), University of Edinburgh; and Department of Psychology (A.J.G.), School of Life Sciences, Heriot-Watt University, Edinburgh, UK.

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http://dx.doi.org/10.1212/WNL.0000000000001075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277669PMC
December 2014

Leisure activity associated with cognitive ability level, but not cognitive change.

Front Psychol 2014 14;5:1176. Epub 2014 Oct 14.

Center for Healthy Aging, University of Copenhagen Copenhagen, Denmark ; Unit of Medical Psychology, Section of Environmental Health, Department of Public Health, University of Copenhagen Copenhagen, Denmark.

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http://dx.doi.org/10.3389/fpsyg.2014.01176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196477PMC
October 2014

Religiosity is negatively associated with later-life intelligence, but not with age-related cognitive decline.

Intelligence 2014 Sep;46:9-17

Department of Psychology, The University of Edinburgh, United Kingdom ; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, United Kingdom.

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http://dx.doi.org/10.1016/j.intell.2014.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175010PMC
September 2014

Associations between level and change in physical function and brain volumes.

PLoS One 2013 12;8(11):e80386. Epub 2013 Nov 12.

Brain Research Imaging Centre, Division of Neuroimaging Sciences, School of Clinical Sciences, University of Edinburgh, Edinburgh, United Kingdom ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, United Kingdom ; SINAPSE (Scottish Imaging Network, A Platform for Scientific Excellence) Collaboration, Edinburgh, United Kingdom ; Department of Computer Science, Faculty of Science, Lagos State University, Lagos, Nigeria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080386PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827194PMC
July 2014

Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory.

Behav Genet 2014 Jul 15;44(4):295-313. Epub 2014 May 15.

Department of Research Methodology, Measurement and Data-Analysis, University of Twente, Enschede, The Netherlands,

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http://dx.doi.org/10.1007/s10519-014-9654-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057636PMC
July 2014

Which social network or support factors are associated with cognitive abilities in old age?

Gerontology 2013 24;59(5):454-63. Epub 2013 May 24.

Centre for Cognitive Ageing and Cognitive Epidemiology, School of Life Sciences, Heriot-Watt University, Edinburgh, UK.

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http://dx.doi.org/10.1159/000351265DOI Listing
April 2014

Vascular risk factors, large-artery atheroma, and brain white matter hyperintensities.

Neurology 2014 Apr 12;82(15):1331-8. Epub 2014 Mar 12.

From the Centre for Clinical Brain Sciences (J.M.W., F.N.D., M.V.H., Z.M., M.B., M.S.D.) and Centre for Cognitive Ageing and Cognitive Epidemiology (M.A., M.V.H., A.J.G., M.B., J.M.S., I.J.D.), University of Edinburgh, UK.

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http://dx.doi.org/10.1212/WNL.0000000000000312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001185PMC
April 2014

Occupational characteristics and cognitive aging in the Glostrup 1914 Cohort.

J Gerontol B Psychol Sci Soc Sci 2014 Mar 7;69(2):228-36. Epub 2012 Dec 7.

Correspondence should be addressed to Alan J. Gow, Ph.D., Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh EH8 9JZ, UK. E-mail:

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http://psychsocgerontology.oxfordjournals.org/cgi/doi/10.109
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http://dx.doi.org/10.1093/geronb/gbs115DOI Listing
March 2014

Circulating inflammatory markers are associated with magnetic resonance imaging-visible perivascular spaces but not directly with white matter hyperintensities.

Stroke 2014 Feb 7;45(2):605-7. Epub 2014 Jan 7.

From Brain Research Imaging Centre (B.S.A., S.W., Z.M., M.C.V.-H., N.A.R., S.M.M., M.E.B., J.M.W.), Centre for Cognitive Ageing and Cognitive Epidemiology (B.S.A., M.C.V.-H., N.A.R., S.M.M., A.J.G., M.E.B., J.S., I.J.D., J.M.W.), Department of Psychology (J.C., I.J.D.), and Geriatric Medicine Unit (J.S.), University of Edinburgh, Edinburgh, United Kingdom; Scottish Imaging Network: A Platform for Scientific Excellence (SINAPSE), Edinburgh, United Kingdom (B.S.A., M.C.V.-H., N.A.R., S.M.M., M.E.B., J.M.W.); Department of Computer Science, Lagos State University, Nigeria (B.S.A.); and Department of Psychology, Heriot-Watt University, United Kingdom (A.J.G.).

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http://dx.doi.org/10.1161/STROKEAHA.113.004059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906539PMC
February 2014

Brain white matter damage in aging and cognitive ability in youth and older age.

Neurobiol Aging 2013 Dec 11;34(12):2740-7. Epub 2013 Jul 11.

Brain Research Imaging Centre, Department of Clinical Neurosciences, University of Edinburgh, Edinburgh, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.05.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898072PMC
December 2013

Estimated maximal and current brain volume predict cognitive ability in old age.

Neurobiol Aging 2013 Dec 11;34(12):2726-33. Epub 2013 Jul 11.

Brain Research Imaging Centre, Neuroimaging Sciences, University of Edinburgh, Edinburgh, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK; Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, Edinburgh, UK; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988920PMC
December 2013

Cytomegalovirus infection and cognitive abilities in old age.

Neurobiol Aging 2013 Jul 22;34(7):1846-52. Epub 2013 Feb 22.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.01.011DOI Listing
July 2013

Symmetry of the face in old age reflects childhood social status.

Econ Hum Biol 2013 Mar 19;11(2):236-44. Epub 2011 Jul 19.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.ehb.2011.06.006DOI Listing
March 2013

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.

Authors:
Anna Köttgen Eva Albrecht Alexander Teumer Veronique Vitart Jan Krumsiek Claudia Hundertmark Giorgio Pistis Daniela Ruggiero Conall M O'Seaghdha Toomas Haller Qiong Yang Toshiko Tanaka Andrew D Johnson Zoltán Kutalik Albert V Smith Julia Shi Maksim Struchalin Rita P S Middelberg Morris J Brown Angelo L Gaffo Nicola Pirastu Guo Li Caroline Hayward Tatijana Zemunik Jennifer Huffman Loic Yengo Jing Hua Zhao Ayse Demirkan Mary F Feitosa Xuan Liu Giovanni Malerba Lorna M Lopez Pim van der Harst Xinzhong Li Marcus E Kleber Andrew A Hicks Ilja M Nolte Asa Johansson Federico Murgia Sarah H Wild Stephan J L Bakker John F Peden Abbas Dehghan Maristella Steri Albert Tenesa Vasiliki Lagou Perttu Salo Massimo Mangino Lynda M Rose Terho Lehtimäki Owen M Woodward Yukinori Okada Adrienne Tin Christian Müller Christopher Oldmeadow Margus Putku Darina Czamara Peter Kraft Laura Frogheri Gian Andri Thun Anne Grotevendt Gauti Kjartan Gislason Tamara B Harris Lenore J Launer Patrick McArdle Alan R Shuldiner Eric Boerwinkle Josef Coresh Helena Schmidt Michael Schallert Nicholas G Martin Grant W Montgomery Michiaki Kubo Yusuke Nakamura Toshihiro Tanaka Patricia B Munroe Nilesh J Samani David R Jacobs Kiang Liu Pio D'Adamo Sheila Ulivi Jerome I Rotter Bruce M Psaty Peter Vollenweider Gerard Waeber Susan Campbell Olivier Devuyst Pau Navarro Ivana Kolcic Nicholas Hastie Beverley Balkau Philippe Froguel Tõnu Esko Andres Salumets Kay Tee Khaw Claudia Langenberg Nicholas J Wareham Aaron Isaacs Aldi Kraja Qunyuan Zhang Philipp S Wild Rodney J Scott Elizabeth G Holliday Elin Org Margus Viigimaa Stefania Bandinelli Jeffrey E Metter Antonio Lupo Elisabetta Trabetti Rossella Sorice Angela Döring Eva Lattka Konstantin Strauch Fabian Theis Melanie Waldenberger H-Erich Wichmann Gail Davies Alan J Gow Marcel Bruinenberg Ronald P Stolk Jaspal S Kooner Weihua Zhang Bernhard R Winkelmann Bernhard O Boehm Susanne Lucae Brenda W Penninx Johannes H Smit Gary Curhan Poorva Mudgal Robert M Plenge Laura Portas Ivana Persico Mirna Kirin James F Wilson Irene Mateo Leach Wiek H van Gilst Anuj Goel Halit Ongen Albert Hofman Fernando Rivadeneira Andre G Uitterlinden Medea Imboden Arnold von Eckardstein Francesco Cucca Ramaiah Nagaraja Maria Grazia Piras Matthias Nauck Claudia Schurmann Kathrin Budde Florian Ernst Susan M Farrington Evropi Theodoratou Inga Prokopenko Michael Stumvoll Antti Jula Markus Perola Veikko Salomaa So-Youn Shin Tim D Spector Cinzia Sala Paul M Ridker Mika Kähönen Jorma Viikari Christian Hengstenberg Christopher P Nelson James F Meschia Michael A Nalls Pankaj Sharma Andrew B Singleton Naoyuki Kamatani Tanja Zeller Michel Burnier John Attia Maris Laan Norman Klopp Hans L Hillege Stefan Kloiber Hyon Choi Mario Pirastu Silvia Tore Nicole M Probst-Hensch Henry Völzke Vilmundur Gudnason Afshin Parsa Reinhold Schmidt John B Whitfield Myriam Fornage Paolo Gasparini David S Siscovick Ozren Polašek Harry Campbell Igor Rudan Nabila Bouatia-Naji Andres Metspalu Ruth J F Loos Cornelia M van Duijn Ingrid B Borecki Luigi Ferrucci Giovanni Gambaro Ian J Deary Bruce H R Wolffenbuttel John C Chambers Winfried März Peter P Pramstaller Harold Snieder Ulf Gyllensten Alan F Wright Gerjan Navis Hugh Watkins Jacqueline C M Witteman Serena Sanna Sabine Schipf Malcolm G Dunlop Anke Tönjes Samuli Ripatti Nicole Soranzo Daniela Toniolo Daniel I Chasman Olli Raitakari W H Linda Kao Marina Ciullo Caroline S Fox Mark Caulfield Murielle Bochud Christian Gieger

Nat Genet 2013 Feb 23;45(2):145-54. Epub 2012 Dec 23.

Renal Division, Freiburg University Hospital, Freiburg, Germany.

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February 2013

Cohort profile: the Lothian Birth Cohorts of 1921 and 1936.

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Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, UK.

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December 2012

Predicting mortality from human faces.

Psychosom Med 2012 Jul-Aug;74(6):560-6. Epub 2012 Jun 28.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, UK.

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November 2012

Lifestyle Factors and Cognitive Ageing: Variation across Ability and Lifestyle Domains.

J Aging Res 2012 4;2012:143595. Epub 2012 Nov 4.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh EH8 9JZ, UK.

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Activity participation and cognitive aging from age 50 to 80 in the glostrup 1914 cohort.

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Section of Social Medicine, University of Copenhagen, Copenhagen, Denmark.

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October 2012

Neuroprotective lifestyles and the aging brain: activity, atrophy, and white matter integrity.

Neurology 2012 Oct;79(17):1802-8

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, UK.

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October 2012

Minor physical anomalies, intelligence, and cognitive decline.

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Centre for Cognitive Ageing and Cognitive Epidemiology and Department of Psychology, University of Edinburgh, Edinburgh, UK.

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August 2012

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J Psychosom Res 2012 Aug 26;73(2):132-8. Epub 2012 Apr 26.

Department of Psychology, University of Edinburgh, UK.

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August 2012

Psychosocial factors and health as determinants of quality of life in community-dwelling older adults.

Qual Life Res 2012 Apr 26;21(3):505-16. Epub 2011 Jun 26.

Department of Psychology, University of Edinburgh, 7 George Square, Scotland, Edinburgh, EH8 9JZ, UK.

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April 2012

Brain iron deposits are associated with general cognitive ability and cognitive aging.

Neurobiol Aging 2012 Mar 9;33(3):510-517.e2. Epub 2010 Jun 9.

Department of Psychology, The University of Edinburgh, Edinburgh, United Kingdom.

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March 2012

Reverse causation in activity-cognitive ability associations: the Lothian Birth Cohort 1936.

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Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, UK.

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March 2012

Is age kinder to the initially more able?: Yes, and no.

Intelligence 2012 Jan;40(1):49-59

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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January 2012

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Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK.

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November 2011

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Centre for Population Health Sciences, The University of Edinburgh, Medical School, Teviot Place, Edinburgh EH8 9AG, Scotland, UK.

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September 2011

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Department of Medicine for the Elderly, Woodend Hospital, Eday Road, Aberdeen AB15 6XS, UK.

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July 2011

A stairway to heaven? Structure of the religious involvement inventory and spiritual well-being scale.

J Relig Health 2011 Mar;50(1):5-19

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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March 2011

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Department of Psychology, University of Edinburgh, Centre for Cognitive Ageing and Cognitive Epidemiology, Edinburgh EH8 9JZ, Scotland.

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March 2011

Alcohol intake and cognitive abilities in old age: the Lothian Birth Cohort 1936 study.

Neuropsychology 2011 Mar;25(2):166-75

Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, Scotland.

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March 2011

Is body mass index in old age related to cognitive abilities? The Lothian Birth Cohort 1936 Study.

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Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh, Scotland.

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December 2010

Association of existing and new candidate genes for anxiety, depression and personality traits in older people.

Behav Genet 2010 Jul 6;40(4):518-32. Epub 2010 Jan 6.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, 7 George Square, Edinburgh, Scotland, UK.

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July 2010

Variation in the uric acid transporter gene (SLC2A9) and memory performance.

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Department of Psychology, The University of Edinburgh, Centre for Cognitive Ageing and Cognitive Epidemiology, 7 George Square, Edinburgh EH8 9JZ, UK.

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June 2010

Age-associated cognitive decline.

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April 2010

Common variants of large effect in F12, KNG1, and HRG are associated with activated partial thromboplastin time.

Am J Hum Genet 2010 Apr 18;86(4):626-31. Epub 2010 Mar 18.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, The University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK.

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Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, The University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK.

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Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, Scotland, UK.

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February 2010

Genetic variants associated with altered plasma levels of C-reactive protein are not associated with late-life cognitive ability in four Scottish samples.

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Public Health Sciences Section, Division of Community Health Sciences, Centre for Population Health Sciences, University of Edinburgh, Medical School, Teviot Place, EH8 9AG Edinburgh, Scotland, UK.

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Division of Clinical Neuroscience, The University of Edinburgh, 1 George Square, Edinburgh EH8 9JZ, United Kingdom.

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June 2009

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Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK.

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Cognitive ability at age 11 and 70 years, information processing speed, and APOE variation: the Lothian Birth Cohort 1936 study.

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Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK.

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Department of Psychology, University of Edinburgh, Edinburgh, UK.

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July 2008

Lifetime intellectual function and satisfaction with life in old age: longitudinal cohort study.

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Department of Psychology, University of Edinburgh, Edinburgh EH8 9JZ.

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Department of Psychology, The University of Edinburgh, Edinburgh, United Kingdom.

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September 2004