Publications by authors named "Alan J Burns"

60Publications

Combined treatment with enteric neural stem cells and chondroitinase ABC reduces spinal cord lesion pathology.

Stem Cell Res Ther 2021 Jan 6;12(1):10. Epub 2021 Jan 6.

Stem Cells and Regenerative Medicine, UCL Great Ormond Street Institute of Child Health, London, UK.

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January 2021

Retinoic Acid Accelerates the Specification of Enteric Neural Progenitors from In-Vitro-Derived Neural Crest.

Stem Cell Reports 2020 09 27;15(3):557-565. Epub 2020 Aug 27.

Stem Cells and Regenerative Medicine, UCL Great Ormond Street Institute of Child Health, London, UK. Electronic address:

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September 2020

Cellular mechanisms underlying related neural tube defects and their prevention by folic acid.

Dis Model Mech 2019 11 22;12(11). Epub 2019 Nov 22.

Developmental Biology and Cancer Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK

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November 2019

Using a Three-Dimensional Collagen Matrix to Deliver Respiratory Progenitor Cells to Decellularized Trachea In Vivo.

Tissue Eng Part C Methods 2019 02;25(2):93-102

1 Lungs for Living Research Centre, UCL Respiratory, Division of Medicine, University College London, London, United Kingdom.

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February 2019

Neuronal Development and Onset of Electrical Activity in the Human Enteric Nervous System.

Gastroenterology 2019 Apr 2;156(5):1483-1495.e6. Epub 2019 Jan 2.

Stem Cells and Regenerative Medicine, UCL Great Ormond Street Institute of Child Health, London, UK; Prince Abdullah Ben Khalid Celiac Research Chair, College of Medicine, King Saud University, Riyadh, KSA; Department of Gastroenterology, Great Ormond Street Hospital, London, UK. Electronic address:

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April 2019

Transplanted enteric neural stem cells integrate within the developing chick spinal cord: implications for spinal cord repair.

J Anat 2018 11 7;233(5):592-606. Epub 2018 Sep 7.

Stem Cells and Regenerative Medicine, UCL Great Ormond Street Institute of Child Health, London, UK.

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November 2018

Decellularized Diaphragmatic Muscle Drives a Constructive Angiogenic Response In Vivo.

Int J Mol Sci 2018 Apr 28;19(5). Epub 2018 Apr 28.

Stem Cells and Regenerative Medicine Lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padova 35127 Italy.

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April 2018

Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest.

Proc Natl Acad Sci U S A 2017 11 24;114(45):11980-11985. Epub 2017 Oct 24.

Institut de Biologie de l'École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, PSL Research University, 75005 Paris, France;

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November 2017

Transplantation of enteric nervous system stem cells rescues nitric oxide synthase deficient mouse colon.

Nat Commun 2017 07 3;8:15937. Epub 2017 Jul 3.

Stem Cells and Regenerative Medicine, UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London WC1N, UK.

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July 2017

The enteric nervous system: From embryology to therapy.

Dev Biol 2016 09;417(2):127-8

Stem Cells and Regenerative Medicine, Birth Defects Research Centre, UCL Great Ormond Street Institute of Child Health, London, UK; Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands.

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September 2016

Genetics of enteric neuropathies.

Dev Biol 2016 09 15;417(2):198-208. Epub 2016 Jul 15.

Department of Clinical Genetics, Erasmus University Medical Centre - Sophia Children's Hospital, Rotterdam, The Netherlands.

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September 2016

Regulators of gene expression in Enteric Neural Crest Cells are putative Hirschsprung disease genes.

Dev Biol 2016 08 4;416(1):255-265. Epub 2016 Jun 4.

Department of Neuroscience, section Medical Physiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

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August 2016

Enteric nervous system development in avian and zebrafish models.

Dev Biol 2016 09 26;417(2):129-38. Epub 2016 May 26.

Stem Cells and Regenerative Medicine, UCL Institute of Child Health, London, UK; Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands. Electronic address:

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September 2016

Dual labeling of neural crest cells and blood vessels within chicken embryos using Chick(GFP) neural tube grafting and carbocyanine dye DiI injection.

J Vis Exp 2015 May 28(99):e52514. Epub 2015 May 28.

Birth Defects Research Centre, UCL Institute of Child Health; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam;

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May 2015

Enteric neurospheres are not specific to neural crest cultures: implications for neural stem cell therapies.

PLoS One 2015 23;10(3):e0119467. Epub 2015 Mar 23.

Stem Cells and Regenerative Medicine, UCL Institute of Child Health, London, United Kingdom; Department of Gastroenterology, Great Ormond Street Hospital for Children, London, United Kingdom.

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March 2016

FKBPL is a critical antiangiogenic regulator of developmental and pathological angiogenesis.

Arterioscler Thromb Vasc Biol 2015 Apr 12;35(4):845-54. Epub 2015 Mar 12.

From the McClay Research Centre for Pharmaceutical Sciences, School of Pharmacy (A.Y., R.B., M.H., O.L., A.S., H.M., L.N., C.M.M., R.M., L.M., H.O.M., T.R.), Centre for Infection and Immunity (M.H., O.L., A.K.), and Northern Ireland Molecular Pathology Laboratory, Centre for Cancer Research and Cell Biology (K.A.), School of Medicine, Dentistry and Biomedical Sciences, Queen's University, Belfast, UK; School of Immunity and Infection and Cancer Studies, Institute for Biomedical Research, University of Birmingham, Birmingham, UK (I.H.-N., R.B.); Centre for Digestive Diseases, Queen Mary, University of London, Barts and The London School of Medicine and Dentistry, London, UK (J.-M.D.); and Birth Defects Research Centre, UCL Institute of Child Health, London, UK (J.-M.D., A.J.B.).

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April 2015

Neural stem cell therapies for enteric nervous system disorders.

Nat Rev Gastroenterol Hepatol 2014 05 10;11(5):317-28. Epub 2013 Dec 10.

1] Neural Development and Gastroenterology Units, Birth Defects Research Centre, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK. [2] Division of Neurogastroenterology and Motility, Department of Paediatric Gastroenterology, Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, UK.

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May 2014

Vascularisation is not necessary for gut colonisation by enteric neural crest cells.

Dev Biol 2014 Jan 18;385(2):220-9. Epub 2013 Nov 18.

Neural Development Unit, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, United Kingdom; Department of Clinical Genetics, The Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address:

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January 2014

Immunomodulatory effect of a decellularized skeletal muscle scaffold in a discordant xenotransplantation model.

Proc Natl Acad Sci U S A 2013 Aug 12;110(35):14360-5. Epub 2013 Aug 12.

Department of Surgery and Neural Development Unit, University College London Institute of Child Health, London WC1N 1EH, United Kingdom.

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August 2013

Immunophenotypic characterization of enteric neural crest cells in the developing avian colorectum.

Dev Dyn 2012 May 23;241(5):842-51. Epub 2012 Mar 23.

Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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May 2012

The enteric nervous system.

Dev Biol 2012 Jun 24;366(1):64-73. Epub 2012 Jan 24.

Division of Molecular Neurobiology, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.

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June 2012

Genetics of human enteric neuropathies.

Prog Neurobiol 2012 Feb 14;96(2):176-89. Epub 2012 Jan 14.

Department of Human Genetics, University of Utah, Salt Lake City, UT, USA.

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February 2012

Stem cells for GI motility disorders.

Curr Opin Pharmacol 2011 Dec 4;11(6):617-23. Epub 2011 Nov 4.

Department of Anatomy & Cell Biology, University of Melbourne, Victoria, Australia.

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December 2011

Analysis of the sacral neural crest cell contribution to the hindgut enteric nervous system in the mouse embryo.

Gastroenterology 2011 Sep 13;141(3):992-1002.e1-6. Epub 2011 Jun 13.

School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.

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September 2011

Variants in RET associated with Hirschsprung's disease affect binding of transcription factors and gene expression.

Gastroenterology 2011 Feb 25;140(2):572-582.e2. Epub 2010 Oct 25.

Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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February 2011

Chitosan-based hydrogels do not induce angiogenesis.

J Tissue Eng Regen Med 2010 Jun;4(4):309-15

School of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London E1 4NS, UK.

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June 2010

Development of the enteric nervous system and its role in intestinal motility during fetal and early postnatal stages.

Semin Pediatr Surg 2009 Nov;18(4):196-205

Neural Development Unit, UCL Institute of Child Health, London, United Kingdom.

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November 2009

Microporous collagen spheres produced via thermally induced phase separation for tissue regeneration.

Acta Biomater 2010 Mar 4;6(3):1158-66. Epub 2009 Sep 4.

Biomaterials and Tissue Engineering Group, Centre for Gastroenterology & Nutrition, University College London, London, UK.

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March 2010

Enteric nervous system stem cells derived from human gut mucosa for the treatment of aganglionic gut disorders.

Gastroenterology 2009 Jun;136(7):2214-25.e1-3

Gastroenterology, Institute of Child Health, University College London, London, United Kingdom.

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June 2009

Disorders of interstitial cells of Cajal.

Authors:
Alan J Burns

J Pediatr Gastroenterol Nutr 2007 Dec;45 Suppl 2:S103-6

Neural Development Unit, University College London Institute of Child Health, London, UK.

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December 2007

The receptor tyrosine kinase RET regulates hindgut colonization by sacral neural crest cells.

Dev Biol 2008 Jan 25;313(1):279-92. Epub 2007 Oct 25.

Neural Development Unit, UCL Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK.

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January 2008

Development of the neural crest-derived intrinsic innervation of the human lung.

Am J Respir Cell Mol Biol 2008 Mar 20;38(3):269-75. Epub 2007 Sep 20.

Neural Development Unit, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK.

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March 2008

Migration of neural crest-derived enteric nervous system precursor cells to and within the gastrointestinal tract.

Authors:
Alan J Burns

Int J Dev Biol 2005 ;49(2-3):143-50

Neural Development Unit, Institute of Child Health, University College London, London, UK.

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September 2005

Development of the enteric nervous system, smooth muscle and interstitial cells of Cajal in the human gastrointestinal tract.

Cell Tissue Res 2005 Mar 26;319(3):367-82. Epub 2005 Jan 26.

Neural Development Unit, Institute of Child Health, University College London, 30 Guilford Street, London, WC1N 1EH, UK.

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March 2005

Neural crest cell origin for intrinsic ganglia of the developing chicken lung.

Dev Biol 2005 Jan;277(1):63-79

Neural Development Unit, Institute of Child Health, University College London, London, UK.

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January 2005

Hepatic nervous system development.

Anat Rec A Discov Mol Cell Evol Biol 2004 Sep;280(1):848-53

Neural Development Unit, Institute of Child Health, University College London, UK.

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September 2004

In ovo transplantation of enteric nervous system precursors from vagal to sacral neural crest results in extensive hindgut colonisation.

Development 2002 Jun;129(12):2785-96

Neural Development Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK.

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June 2002