Alan Huang

Alan Huang

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Alan Huang

Alan Huang

Publications by authors named "Alan Huang"

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Let's Talk About B: Barriers to Hepatitis B Screening and Vaccination Among Asian and South Asian Immigrants in British Columbia.

J Racial Ethn Health Disparities 2018 12 19;5(6):1337-1345. Epub 2018 Mar 19.

Digital Emergency Medicine, Department of Emergency Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1007/s40615-018-0483-0DOI Listing
December 2018

Differential responses of MET activations to MET kinase inhibitor and neutralizing antibody.

J Transl Med 2018 09 12;16(1):253. Epub 2018 Sep 12.

Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City, TN, 37614, USA.

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http://dx.doi.org/10.1186/s12967-018-1628-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134500PMC
September 2018

Phosphatidylinositol 3-Kinase α-Selective Inhibition With Alpelisib (BYL719) in PIK3CA-Altered Solid Tumors: Results From the First-in-Human Study.

J Clin Oncol 2018 05 5;36(13):1291-1299. Epub 2018 Feb 5.

Dejan Juric, Massachusetts General Hospital Cancer Center, Boston; Alan Huang, Novartis Institutes for BioMedical Research, Cambridge, MA; Jordi Rodon and Josep Tabernero, Vall d'Hebron University Hospital and Institute of Oncology, Universitat Autònoma de Barcelona; Marta Gil-Martin, Catalan Institute of Oncology - Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain; Filip Janku, The University of Texas MD Anderson Cancer Center, Houston, TX; Howard A. Burris, Sarah Cannon Research Institute and Tennessee Oncology; Jordan Berlin, Vanderbilt-Ingram Cancer Center, Nashville, TN; Jan H.M. Schellens, Netherlands Cancer Institute, Amsterdam, the Netherlands; Mark R. Middleton, National Institute for Health Research, Oxford Biomedical Research Centre, Churchill Hospital, Oxford, United Kingdom; Martin Schuler, West German Cancer Center, University Duisburg-Essen, and German Cancer Consortium, Partner Site University Hospital Essen, Essen; Ruth Seggewiss-Bernhardt, Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany; Hope S. Rugo, University of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, CA; Douglas Bootle, David Demanse, Lars Blumenstein, and Cornelia Quadt, Novartis Pharma AG, Basel, Switzerland; Christina Coughlin, Novartis Pharmaceuticals Corporation, East Hanover, NJ; and José Baselga, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://ascopubs.org/doi/10.1200/JCO.2017.72.7107
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http://dx.doi.org/10.1200/JCO.2017.72.7107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920739PMC
May 2018

Transverse water relaxation in whole blood and erythrocytes at 3T, 7T, 9.4T, 11.7T and 16.4T; determination of intracellular hemoglobin and extracellular albumin relaxivities.

Magn Reson Imaging 2017 05 16;38:234-249. Epub 2016 Dec 16.

The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA; F.M. Kirby Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mri.2016.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437867PMC
May 2017

Hepatitis B Awareness and Knowledge in Asian Communities in British Columbia.

Can J Gastroenterol Hepatol 2016 29;2016:4278724. Epub 2016 Mar 29.

Division of Gastroenterology, Department of Medicine, University of British Columbia, GLDHCC, 2775 Laurel Street, 5th Floor, Vancouver, BC, Canada V5Z 1M9.

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http://dx.doi.org/10.1155/2016/4278724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904637PMC
March 2017

Prostatic Acid Phosphatase Alters the RANKL/OPG System and Induces Osteoblastic Prostate Cancer Bone Metastases.

Endocrinology 2016 Dec 26;157(12):4526-4533. Epub 2016 Oct 26.

Department of Urology (A.K.); Department of Genetics and Genomic Sciences (S.I.), Graduate School of Biomedical Sciences; and Division of Endocrinology, Diabetes and Bone Disease (S.Yao, K.L.O.-C., A.H., E.M.G., A.C.L.), Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029; and Departments of Basic Science and Craniofacial Biology (S.Yak.), New York University College of Dentistry, New York, New York 10010.

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http://dx.doi.org/10.1210/en.2016-1606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133341PMC
December 2016

Orthogonality of the Mean and Error Distribution in Generalized Linear Models.

Commun Stat Theory Methods 2017 17;46(7):3290-3296. Epub 2016 Nov 17.

University of Technology Sydney and University of Wisconsin-Madison.

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http://dx.doi.org/10.1080/03610926.2013.851241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396964PMC
November 2016

Quantitative theory for the longitudinal relaxation time of blood water.

Magn Reson Med 2016 07 18;76(1):270-81. Epub 2015 Aug 18.

Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1002/mrm.25875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758918PMC
July 2016

Correlative Analysis of Genetic Alterations and Everolimus Benefit in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: Results From BOLERO-2.

J Clin Oncol 2016 Feb 26;34(5):419-26. Epub 2015 Oct 26.

Gabriel N. Hortobagyi, University of Texas MD Anderson Cancer Center, Houston, TX; David Chen, Tetiana Taran, and David Lebwohl, Novartis Pharmaceuticals, East Hanover, NJ; Martine Piccart and Fabienne Lebrun, Université Libre de Bruxelles, Brussels; Ines Deleu, Oncology Centre, AZ Nikolaas, Sint-Nikolaas, Belgium; Hope S. Rugo, University of California, San Francisco; Ian Anderson, Redwood Regional Oncology Center, Santa Rosa, CA; Howard A. Burris III, Sarah Cannon Research Institute, Nashville, TN; Kathleen I. Pritchard, Sunnybrook Odette Cancer Centre and the University of Toronto, Toronto, Ontario, Canada; Mario Campone, Centre de Recherche en Cancerologie, Nantes-Saint-Herblain; Thomas Bachelot, Centre Léon Bérard, Lyon, France; Shinzaburo Noguchi, Osaka University Medical School; Norikazu Masuda, Osaka National Hospital, Osaka, Japan; Alejandra T. Perez, Memorial Cancer Institute, Hollywood, FL; Mikhail Shtivelband, Ironwood Cancer & Research Centers, Chandler, AZ; Shaker Dakhil, Cancer Center of Kansas, Wichita, KS; Douglas M. Robinson, Wei He, Abhishek Garg, E. Robert McDonald III, Hans Bitter, and Alan Huang, Novartis Institutes for BioMedical Research, Cambridge, MA; and José Baselga, Memorial Sloan-Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1200/JCO.2014.60.1971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070556PMC
February 2016

Fatal pulmonary embolization after negative serial ultrasounds.

J Emerg Med 2015 Feb 13;48(2):158-60. Epub 2014 Nov 13.

Elmhurst Hospital Center, Mount Sinai School of Medicine, New York, New York.

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http://dx.doi.org/10.1016/j.jemermed.2014.10.006DOI Listing
February 2015

Characterization of the novel and specific PI3Kα inhibitor NVP-BYL719 and development of the patient stratification strategy for clinical trials.

Mol Cancer Ther 2014 May 7;13(5):1117-29. Epub 2014 Mar 7.

Authors' Affiliations: Novartis Institutes for BioMedical Research, Disease Area Oncology; Novartis Institutes for BioMedical Research, Global Discovery Chemistry; Novartis Institutes for BioMedical Research, Center for Proteomic Chemistry; Novartis Pharma AG, Oncology Translational Medicine, Basel, Switzerland; Novartis Pharma AG, Oncology Translational Medicine; Novartis Institutes for BioMedical Research, Developmental and Molecular Pathways, Cambridge, Massachusetts; and Novartis Institutes for BioMedical Research, Developmental and Molecular Pathways, Shangai, China.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0865DOI Listing
May 2014

MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells.

Elife 2014 May 20;3:e01763. Epub 2014 May 20.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, United States Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, United States

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https://elifesciences.org/articles/01763
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http://dx.doi.org/10.7554/eLife.01763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059381PMC
May 2014

Three-dimensional whole-brain perfusion quantification using pseudo-continuous arterial spin labeling MRI at multiple post-labeling delays: accounting for both arterial transit time and impulse response function.

NMR Biomed 2014 Feb 16;27(2):116-28. Epub 2013 Oct 16.

Russell H. Morgan Department of Radiology and Radiological Science Division of MR Research, Johns Hopkins University School of Medicine, Baltimore, MD, USA; F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/nbm.3040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947417PMC
February 2014

An antibody that locks HER3 in the inactive conformation inhibits tumor growth driven by HER2 or neuregulin.

Cancer Res 2013 Oct 8;73(19):6024-35. Epub 2013 Aug 8.

Authors' Affiliations: Novartis Institutes for Biomedical Research, Cambridge, Massachusetts; Departments of Medicine and Cancer Biology; Breast Cancer Research Program, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee; MorphoSys AG, Martinsried, Germany; and Genomics Institute of the Novartis Research Foundation, San Diego, California.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924863PMC
October 2013

Nuclear Overhauser enhancement (NOE) imaging in the human brain at 7T.

Neuroimage 2013 Aug 6;77:114-24. Epub 2013 Apr 6.

Division of MR Research, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2013.03.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848060PMC
August 2013

Proportional likelihood ratio models for mean regression.

Biometrika 2012 Mar;99(1):223-229

Department of Biostatistics & Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin 53792, USA.

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http://dx.doi.org/10.1093/biomet/asr075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888642PMC
March 2012

The prion protein binds thiamine.

FEBS J 2011 Nov 15;278(21):4002-14. Epub 2011 Sep 15.

Department of Biological Sciences, University of Alberta, Edmonton, AB, Canada.

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http://dx.doi.org/10.1111/j.1742-4658.2011.08304.xDOI Listing
November 2011

Physiological origin for the BOLD poststimulus undershoot in human brain: vascular compliance versus oxygen metabolism.

J Cereb Blood Flow Metab 2011 Jul 6;31(7):1599-611. Epub 2011 Apr 6.

Russell H Morgan Department of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1038/jcbfm.2011.35DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137471PMC
July 2011

Discovery and optimization of CRTH2 and DP dual antagonists.

Bioorg Med Chem Lett 2009 Nov 17;19(22):6419-23. Epub 2009 Sep 17.

Amgen Inc., 1120 Veterans Boulevard, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1016/j.bmcl.2009.09.052DOI Listing
November 2009

Immunological mimicry of PrPC-PrPSc interactions: antibody-induced PrP misfolding.

Protein Eng Des Sel 2009 Aug 14;22(8):523-9. Epub 2009 Jul 14.

Brain Research Centre, The University of British Columbia, 2211 Wesbrook Mall, Vancouver, BC, Canada.

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http://dx.doi.org/10.1093/protein/gzp038DOI Listing
August 2009

Magnetization transfer enhanced vascular-space-occupancy (MT-VASO) functional MRI.

Magn Reson Med 2009 Apr;61(4):944-51

The Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://doi.wiley.com/10.1002/mrm.21911
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http://dx.doi.org/10.1002/mrm.21911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728078PMC
April 2009

Single-vector inducible lentiviral RNAi system for oncology target validation.

Cell Cycle 2009 Feb 25;8(3):498-504. Epub 2009 Feb 25.

Oncology Research, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.4161/cc.8.3.7701DOI Listing
February 2009

NMR studies of interactions between C-terminal tail of Kir2.1 channel and PDZ1,2 domains of PSD95.

Biochemistry 2007 May 17;46(18):5315-22. Epub 2007 Apr 17.

Structural Biology, The Salk Institute, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1021/bi062228qDOI Listing
May 2007

Simultaneous quantitation of the nucleotide analog adefovir, its phosphorylated anabolites and 2'-deoxyadenosine triphosphate by ion-pairing LC/MS/MS.

J Chromatogr B Analyt Technol Biomed Life Sci 2007 Apr 13;848(2):335-43. Epub 2006 Nov 13.

Gilead Sciences, Foster City, CA 94404, USA.

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http://dx.doi.org/10.1016/j.jchromb.2006.10.063DOI Listing
April 2007

It is time to move: role of lateral diffusion in AMPA receptor trafficking.

J Neurosci 2006 Sep;26(36):9082-3

Brain Research Centre, University of British Columbia, Vancouver, British Columbia, Canada V6T 2B5.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6674522PMC
September 2006