Alan E Hubbard

Alan E Hubbard

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Alan E Hubbard

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Functional Profiling Identifies Determinants of Arsenic Trioxide Cellular Toxicity.

Toxicol Sci 2019 05;169(1):108-121

Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida.

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http://dx.doi.org/10.1093/toxsci/kfz024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484884PMC
May 2019

Dynamic multi-outcome prediction after injury: Applying adaptive machine learning for precision medicine in trauma.

PLoS One 2019 10;14(4):e0213836. Epub 2019 Apr 10.

Denver Health Medical Center and the University of Colorado; Denver, Colorado, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213836PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457612PMC
April 2019

Identification of gene expression predictors of occupational benzene exposure.

PLoS One 2018 9;13(10):e0205427. Epub 2018 Oct 9.

Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205427PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177191PMC
March 2019

Machine learning without borders? An adaptable tool to optimize mortality prediction in diverse clinical settings.

J Trauma Acute Care Surg 2018 11;85(5):921-927

From the Department of Surgery (S.A.C., R.A.C., C.J.), University of California San Francisco, San Francisco, California; Department of Biostatistics (A.E.H.), University of California Berkeley, Berkeley, California; Division of General Surgery (M.H.), Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada; Littoral Regional Delegation of the Ministry of Public Health, Cameroon (F.N.D.-D.), Douala, Cameroon; Laquintinie Hospital of Douala, Douala, Cameroon (D.M., A.S.); Regional Hospital of Limbe, Limbe, Cameroon (A.C.M.); Catholic Hospital of Pouma, Pouma, Cameroon (P.N.); Department of Surgery (R.A.D.), University of California Los Angeles, Los Angeles, California; and Denver Health Medical Center and the University of Colorado, Denver, Colorado (M.J.C.).

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http://dx.doi.org/10.1097/TA.0000000000002044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225991PMC
November 2018

Spillover effects in epidemiology: parameters, study designs and methodological considerations.

Int J Epidemiol 2018 02;47(1):332-347

Division of Biostatistics, UC Berkeley School of Public Health, 101 Haviland Hall, Berkeley, CA 94720-7358, USA.

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http://dx.doi.org/10.1093/ije/dyx201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837695PMC
February 2018

Collaborative targeted maximum likelihood estimation for variable importance measure: Illustration for functional outcome prediction in mild traumatic brain injuries.

Stat Methods Med Res 2018 01 29;27(1):286-297. Epub 2016 Jun 29.

4 Division of Biostatistics, School of Public Health, University of California Berkeley, Berkeley, CA, USA.

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http://dx.doi.org/10.1177/0962280215627335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589499PMC
January 2018

Finding the signal in the noise: Could social media be utilized for early hospital notification of multiple casualty events?

PLoS One 2017 5;12(10):e0186118. Epub 2017 Oct 5.

Department of Surgery, University of Colorado & Denver Health, Denver, Colorado, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186118PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628942PMC
November 2017

Scaling Up a Water, Sanitation, and Hygiene Program in Rural Bangladesh: The Role of Program Implementation.

Am J Public Health 2017 05 21;107(5):694-701. Epub 2017 Mar 21.

Jade Benjamin-Chung, Benjamin F. Arnold, and John M. Colford Jr are with the Division of Epidemiology, School of Public Health, University of California, Berkeley. Alan E. Hubbard is with the Division of Biostatistics, School of Public Health, University of California, Berkeley. Sonia Sultana, Amal K. Halder, Mohammed Ali Ahsan, and Leanne Unicomb are with the Environmental Interventions Unit, Infectious Disease Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka. Stephen P. Luby is with the Department of Medicine, Stanford University, Stanford, CA.

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http://dx.doi.org/10.2105/AJPH.2017.303686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388951PMC
May 2017

Measuring changes in transmission of neglected tropical diseases, malaria, and enteric pathogens from quantitative antibody levels.

PLoS Negl Trop Dis 2017 May 19;11(5):e0005616. Epub 2017 May 19.

Division of Parasitic Diseases and Malaria, United States Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0005616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453600PMC
May 2017

Reconstructing the Migratory Behavior and Long-Term Survivorship of Juvenile Chinook Salmon under Contrasting Hydrologic Regimes.

PLoS One 2015 20;10(5):e0122380. Epub 2015 May 20.

Department of Animal Sciences, University of California Davis, Davis, California, United States of America; National Marine Fisheries Service, Southwest Fisheries Science Center, Santa Cruz, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122380PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439044PMC
February 2016

Evolving beyond the vicious triad: Differential mediation of traumatic coagulopathy by injury, shock, and resuscitation.

J Trauma Acute Care Surg 2015 Mar;78(3):516-23

From the *Department of Surgery (M.E.K., B.M.H., M.J.C.), University of California, San Francisco, and San Francisco General Hospital, San Francisco; and Division of Biostatistics and School of Public Health (A.E.H., A.L.D.), University of California at Berkeley, Berkeley, California; Department of Surgery (J.L.S.), University of Pittsburgh Medical Center and Presbyterian University Hospital, Pittsburgh, Pennsylvania; Department of Surgery (J.C., R.V.M.), University of Washington School of Medicine and Harborview Medical Center, Seattle, Washington; Department of Surgery (J.P.M.), University of Texas Southwestern Medical Center and Parkland Health and Hospital System, Dallas, Texas; Department of Surgery (E.E.M.), University of Colorado Health Sciences Center and Denver Health Medical Center, Denver, Colorado; and Department of Surgery (B.H.B.), Washington University School of Medicine; St. Louis, Missouri.

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http://dx.doi.org/10.1097/TA.0000000000000545DOI Listing
March 2015

Litigation in obstetrics: does defensive medicine contribute to increases in cesarean delivery?

J Matern Fetal Neonatal Med 2014 Nov 17;27(16):1668-75. Epub 2014 Feb 17.

Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Maternal-Fetal Medicine, University of California , San Francisco, CA , USA .

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http://dx.doi.org/10.3109/14767058.2013.879115DOI Listing
November 2014

Accounting for perception, placebo and unmasking effects in estimating treatment effects in randomised clinical trials.

Stat Methods Med Res 2014 06 8;23(3):293-307. Epub 2011 Sep 8.

Division of Biostatistics, School of Public Health, University of California, Berkeley, CA, USA

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http://journals.sagepub.com/doi/10.1177/0962280211413449
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http://dx.doi.org/10.1177/0962280211413449DOI Listing
June 2014

Optimal recall period for caregiver-reported illness in risk factor and intervention studies: a multicountry study.

Am J Epidemiol 2013 Feb 29;177(4):361-70. Epub 2013 Jan 29.

Division of Epidemiology, School of Public Health, University of California, Berkeley, 101 Haviland Hall, MC7538, Berkeley, CA 94720, USA.

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http://dx.doi.org/10.1093/aje/kws281DOI Listing
February 2013

Organophosphorous pesticide breakdown products in house dust and children's urine.

J Expo Sci Environ Epidemiol 2012 Nov 11;22(6):559-68. Epub 2012 Jul 11.

Center for Environmental Research and Children's Health, School of Public Health, University of California, Berkeley, California 94704, USA.

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http://dx.doi.org/10.1038/jes.2012.46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133088PMC
November 2012

Confidence intervals for negative binomial random variables of high dispersion.

Int J Biostat 2010 ;6(1):Article 10

Stanford University, CA, USA.

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http://dx.doi.org/10.2202/1557-4679.1164DOI Listing
July 2012

Evidence for both innate and acquired mechanisms of protection from Plasmodium falciparum in children with sickle cell trait.

Blood 2012 Apr 10;119(16):3808-14. Epub 2012 Feb 10.

University of California, Berkeley-University of California, San Francisco Joint Medical Program, 94110, USA.

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http://dx.doi.org/10.1182/blood-2011-08-371062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335384PMC
April 2012

Inequalities in body mass index and smoking behavior in 70 countries: evidence for a social transition in chronic disease risk.

Am J Epidemiol 2012 Feb 5;175(3):167-76. Epub 2012 Jan 5.

Center for Social Epidemiology and Population Health, Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, USA.

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https://academic.oup.com/aje/article-lookup/doi/10.1093/aje/
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http://dx.doi.org/10.1093/aje/kwr314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261437PMC
February 2012

Longitudinal change of biomarkers in cognitive decline.

Arch Neurol 2011 Oct 13;68(10):1257-66. Epub 2011 Jun 13.

Division of Epidemiology, University of California, Berkeley, 94720-3190, USA.

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http://dx.doi.org/10.1001/archneurol.2011.123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604752PMC
October 2011

Simulation methods to estimate design power: an overview for applied research.

BMC Med Res Methodol 2011 Jun 20;11:94. Epub 2011 Jun 20.

Division of Epidemiology, School of Public Health, University of California, Berkeley, CA, USA.

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http://dx.doi.org/10.1186/1471-2288-11-94DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146952PMC
June 2011

Chromosome-wide aneuploidy study (CWAS) in workers exposed to an established leukemogen, benzene.

Carcinogenesis 2011 Apr 7;32(4):605-12. Epub 2011 Jan 7.

Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA 94720, USA.

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http://dx.doi.org/10.1093/carcin/bgq286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066415PMC
April 2011

Toxicogenomic profiling of chemically exposed humans in risk assessment.

Mutat Res 2010 Dec 9;705(3):172-83. Epub 2010 Apr 9.

School of Public Health, Divisions of Environmental Health Sciences, and Biostatistics, University of California, Berkeley, CA 94720, USA.

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http://dx.doi.org/10.1016/j.mrrev.2010.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928857PMC
December 2010

Pregnancy intentions and teenage pregnancy among Latinas: a mediation analysis.

Perspect Sex Reprod Health 2010 Sep;42(3):186-96

Bixby Center for Global Reproductive Health, Department of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, University of California, San Francisco, CA, USA.

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http://doi.wiley.com/10.1363/4218610
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http://dx.doi.org/10.1363/4218610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951312PMC
September 2010

Predictive ability and stability of adolescents' pregnancy intentions in a predominantly Latino community.

Stud Fam Plann 2010 Sep;41(3):179-92

Bixby Center for Global Reproductive Health, Department of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, University of California, San Francisco, 3333 California Street, Suite 335, UCSF Box 0744, San Francisco, CA 94143-0744, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265987PMC
http://dx.doi.org/10.1111/j.1728-4465.2010.00242.xDOI Listing
September 2010

Systems biology of human benzene exposure.

Chem Biol Interact 2010 Mar 21;184(1-2):86-93. Epub 2009 Dec 21.

Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA 94720-7356, USA.

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http://dx.doi.org/10.1016/j.cbi.2009.12.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846187PMC
March 2010

Seasonality of rotavirus disease in the tropics: a systematic review and meta-analysis.

Int J Epidemiol 2009 Dec 4;38(6):1487-96. Epub 2008 Dec 4.

Department of Environmental Science, University of California, Berkeley, USA.

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http://dx.doi.org/10.1093/ije/dyn260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800782PMC
December 2009

Drivers of water quality variability in northern coastal Ecuador.

Environ Sci Technol 2009 Mar;43(6):1788-97

Department of Environmental Science, Policy and Management, 137 Mulford Hall #3114, University of California, Berkeley, California 94720-3114, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419269PMC
http://dx.doi.org/10.1021/es8022545DOI Listing
March 2009

Temporal transcriptomic microarray analysis of "Dehalococcoides ethenogenes" strain 195 during the transition into stationary phase.

Appl Environ Microbiol 2008 May 29;74(9):2864-72. Epub 2008 Feb 29.

Department of Civil and Environmental Engineering, University of California, Berkeley, CA 94720-1710, USA.

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http://dx.doi.org/10.1128/AEM.02208-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394897PMC
May 2008

Pharmacogenetic analysis of lithium-induced delayed aging in Caenorhabditis elegans.

J Biol Chem 2008 Jan 24;283(1):350-7. Epub 2007 Oct 24.

Buck Institute for Age Research, Novato, CA 94945, USA.

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http://dx.doi.org/10.1074/jbc.M705028200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739662PMC
January 2008

A comparison of methods to control type I errors in microarray studies.

Stat Appl Genet Mol Biol 2007 11;6:Article28. Epub 2007 Oct 11.

Lawrence Berkeley National Laboratory.

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https://www.degruyter.com/view/j/sagmb.2007.6.issue-1/sagmb.
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http://dx.doi.org/10.2202/1544-6115.1310DOI Listing
January 2008

Population intervention models in causal inference.

Biometrika 2008 ;95(1):35-47

Division of Biostatistics, University of California, Berkeley, California 94720, U.S.A.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464276PMC
http://dx.doi.org/10.1093/biomet/asm097DOI Listing
January 2008

Super learner.

Stat Appl Genet Mol Biol 2007 16;6:Article25. Epub 2007 Sep 16.

University of California, Berkeley, USA.

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http://dx.doi.org/10.2202/1544-6115.1309DOI Listing
November 2007

Depressive symptoms in low-income women in rural Mexico.

Epidemiology 2007 Nov;18(6):678-85

Division of Epidemiology, School of Public Health, University of California, Berkely, CA, USA.

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http://dx.doi.org/10.1097/EDE.0b013e3181567fc5DOI Listing
November 2007

Leukaemia-specific chromosome damage detected by comet with fluorescence in situ hybridization (comet-FISH).

Mutagenesis 2007 Sep 16;22(5):321-7. Epub 2007 Jun 16.

Division of Environmental Health Sciences, School of Public Health, 140 Warren Hall, University of California, Berkeley, California 94720, USA.

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http://dx.doi.org/10.1093/mutage/gem020DOI Listing
September 2007

Aberrations in chromosomes associated with lymphoma and therapy-related leukemia in benzene-exposed workers.

Environ Mol Mutagen 2007 Jul;48(6):467-74

School of Public Health, University of California, Berkeley, California, USA.

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http://dx.doi.org/10.1002/em.20306DOI Listing
July 2007

Early prediction of median survival among a large AIDS surveillance cohort.

BMC Public Health 2007 Jun 27;7:127. Epub 2007 Jun 27.

Division of Epidemiology, School of Public Health, University of California at Berkeley, Berkeley, California, USA.

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http://dx.doi.org/10.1186/1471-2458-7-127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1925077PMC
June 2007

Creating diagnostic scores using data-adaptive regression: An application to prediction of 30-day mortality among stroke victims in a rural hospital in India.

Ther Clin Risk Manag 2007 Jun;3(3):475-84

University of California, Berkeley, School of Public Health, Division of Biostatistics University Hall, Berkeley, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386350PMC
June 2007

Worker exposure to volatile organic compounds in the vehicle repair industry.

J Occup Environ Hyg 2007 May;4(5):301-10

School of Public Health, University of California Berkeley, Berkeley, California 94720-7360, USA.

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http://coeh.berkeley.edu/docs/news/worker_exposure_2007.pdf
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http://www.tandfonline.com/doi/abs/10.1080/15459620701258021
Publisher Site
http://dx.doi.org/10.1080/15459620701258021DOI Listing
May 2007

Microarray analysis of gene expression in peripheral blood mononuclear cells from dioxin-exposed human subjects.

Toxicology 2007 Jan 17;229(1-2):101-13. Epub 2006 Oct 17.

School of Public Health, University of California, Berkeley, CA 94720-7360, USA.

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http://dx.doi.org/10.1016/j.tox.2006.10.004DOI Listing
January 2007

Quantile-function based null distribution in resampling based multiple testing.

Stat Appl Genet Mol Biol 2006 21;5:Article14. Epub 2006 May 21.

Division of Biostatistics, School of Public Health, University of California, Berkeley, CA, USA.

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http://dx.doi.org/10.2202/1544-6115.1199DOI Listing
December 2006

The histone deacetylase inhibitor trichostatin a has genotoxic effects in human lymphoblasts in vitro.

Toxicol Sci 2006 Oct 20;93(2):341-7. Epub 2006 Jul 20.

Molecular Epidemiology and Toxicology Laboratory, School of Public Health, University of California, Berkeley, California 94720-7360, USA.

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http://dx.doi.org/10.1093/toxsci/kfl068DOI Listing
October 2006

Issues of processing and multiple testing of SELDI-TOF MS proteomic data.

Stat Appl Genet Mol Biol 2006 21;5:Article11. Epub 2006 Apr 21.

Division of Biostatistics, School of Public Health, University of California, Berkeley, USA.

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http://dx.doi.org/10.2202/1544-6115.1198DOI Listing
June 2006

Empirical Bayes and resampling based multiple testing procedure controlling tail probability of the proportion of false positives.

Stat Appl Genet Mol Biol 2005 7;4:Article29. Epub 2005 Oct 7.

Division of Biostatistics, School of Public Health, University of California, Berkeley, USA.

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http://dx.doi.org/10.2202/1544-6115.1143DOI Listing
May 2006

Nonrandom aneuploidy of chromosomes 1, 5, 6, 7, 8, 9, 11, 12, and 21 induced by the benzene metabolites hydroquinone and benzenetriol.

Environ Mol Mutagen 2005 May;45(4):388-96

Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, California 94720, USA.

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http://dx.doi.org/10.1002/em.20103DOI Listing
May 2005

Polymorphisms in ghrelin and neuropeptide Y genes are associated with non-Hodgkin lymphoma.

Cancer Epidemiol Biomarkers Prev 2005 May;14(5):1251-6

Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA 94720-7360, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-04-0895DOI Listing
May 2005

Use of OctoChrome fluorescence in situ hybridization to detect specific aneuploidy among all 24 chromosomes in benzene-exposed workers.

Chem Biol Interact 2005 May 19;153-154:117-22. Epub 2005 Apr 19.

School of Public Health, 140 Warren Hall, University of California, Berkeley, CA 94720-7360, USA.

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http://dx.doi.org/10.1016/j.cbi.2005.03.016DOI Listing
May 2005

Use of 'Omic' technologies to study humans exposed to benzene.

Chem Biol Interact 2005 May 19;153-154:123-7. Epub 2005 Apr 19.

School of Public Health, 140 Warren Hall, University of California, Berkeley, CA 94720-7360, USA.

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http://dx.doi.org/10.1016/j.cbi.2005.03.017DOI Listing
May 2005

Statistical estimation of parameters in a disease transmission model: analysis of a Cryptosporidium outbreak.

Stat Med 2002 Dec;21(23):3627-38

Division of Biostatistics, University of California, Berkeley, USA.

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http://dx.doi.org/10.1002/sim.1258DOI Listing
December 2002

Post-abortion depot medroxyprogesterone acetate continuation rates: a randomized trial of cyclic estradiol.

Contraception 2002 Oct;66(4):215-20

The Department of Obstetrics, Gynecology and Reproductive Sciences, Center for Reproductive Health Research and Policy, San Francisco General Hospital, University of California-San Francisco, 94110, USA.

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http://dx.doi.org/10.1016/s0010-7824(02)00391-8DOI Listing
October 2002