Alan D Irvine

Alan D Irvine

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Alan D Irvine

Alan D Irvine

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The role of filaggrin in atopic dermatitis and allergic disease.

Ann Allergy Asthma Immunol 2019 Oct 14. Epub 2019 Oct 14.

Department of Paediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin, National Children's Research Centre, Crumlin and Clinical Medicine, Trinity College Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.anai.2019.10.008DOI Listing
October 2019

The impact of short-term predominate breastfeeding on cognitive outcome at 5 years.

Acta Paediatr 2019 Sep 13. Epub 2019 Sep 13.

Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Cork, IE.

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http://dx.doi.org/10.1111/apa.15014DOI Listing
September 2019

mosaic mutations in patients with capillary malformation-arteriovenous malformation.

J Med Genet 2019 Jul 12. Epub 2019 Jul 12.

Center for Vascular Anomalies, Division of Plastic Surgery, Cliniques universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium; VASCERN VASCA European Reference Center.

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http://dx.doi.org/10.1136/jmedgenet-2019-106024DOI Listing
July 2019

The exposome in atopic dermatitis.

Allergy 2019 Jun 13. Epub 2019 Jun 13.

Department of Paediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin, Ireland.

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http://dx.doi.org/10.1111/all.13946DOI Listing
June 2019

Antimicrobial resistance in atopic dermatitis: Need for an urgent rethink.

Ann Allergy Asthma Immunol 2019 Mar 29;122(3):236-240. Epub 2018 Nov 29.

National Children's Research Centre, Our Lady's Children's Hospital, Crumlin, Dublin, Dublin 12, Ireland; Clinical Medicine, Trinity College Dublin, Dublin, Ireland; Paediatric Dermatology, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.anai.2018.11.027DOI Listing
March 2019

Next-generation anti-Staphylococcus aureus vaccines: A potential new therapeutic option for atopic dermatitis?

J Allergy Clin Immunol 2019 01 12;143(1):78-81. Epub 2018 Sep 12.

Host-Pathogen Interactions Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.08.038DOI Listing
January 2019

The atopic march and atopic multimorbidity: Many trajectories, many pathways.

J Allergy Clin Immunol 2019 01 17;143(1):46-55. Epub 2018 Nov 17.

Paediatric Dermatology and the National Children's Research Centre, Our Lady's Children's Hospital Crumlin, and Clinical Medicine, Trinity College Dublin, Dublin, Ireland.

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183163
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http://dx.doi.org/10.1016/j.jaci.2018.11.006DOI Listing
January 2019

The microbiome in patients with atopic dermatitis.

J Allergy Clin Immunol 2019 01 23;143(1):26-35. Epub 2018 Nov 23.

Paediatric Dermatology, Our Lady's Children's Hospital Crumlin, National Children's Research Centre and Trinity College, Dublin, Ireland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183166
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http://dx.doi.org/10.1016/j.jaci.2018.11.015DOI Listing
January 2019

Antenatal vitamin D exposure and childhood eczema, food allergy, asthma and allergic rhinitis at 2 and 5 years of age in the atopic disease-specific Cork BASELINE Birth Cohort Study.

Allergy 2018 11 29;73(11):2182-2191. Epub 2018 Aug 29.

Cork Centre for Vitamin D and Nutrition Research, School of Food and Nutritional Sciences, University College Cork, Cork, Ireland.

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http://doi.wiley.com/10.1111/all.13590
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http://dx.doi.org/10.1111/all.13590DOI Listing
November 2018

Correlation of Insulin-Like Growth Factor-I and -II Concentrations at Birth Measured by Mass Spectrometry and Growth from Birth to Two Months.

Horm Res Paediatr 2018 18;89(2):122-131. Epub 2018 Jan 18.

Division of Endocrinology and Diabetes, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1159/000486035DOI Listing
September 2018

Response to "Comment on: 'When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council'".

J Am Acad Dermatol 2018 08;79(2):e25-e26

Trinity College Dublin, National Children's Research Centre, Paediatric Dermatology, Our Lady's Children's Hospital, Dublin, Republic of Ireland.

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http://dx.doi.org/10.1016/j.jaad.2018.03.048DOI Listing
August 2018

Generalized lymphatic anomaly successfully treated with long-term, low-dose sirolimus.

Pediatr Dermatol 2018 Jul 26;35(4):533-534. Epub 2018 Mar 26.

Department of Pediatric Dermatology, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland.

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http://dx.doi.org/10.1111/pde.13494DOI Listing
July 2018

Staphylococcus aureus and Atopic Dermatitis: A Complex and Evolving Relationship.

Trends Microbiol 2018 06 9;26(6):484-497. Epub 2017 Dec 9.

Department of Microbiology, Moyne Institute of Preventive Medicine, School of Genetics and Microbiology, Trinity College Dublin, Dublin 2, Ireland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0966842X173025
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http://dx.doi.org/10.1016/j.tim.2017.11.008DOI Listing
June 2018

Atopic dermatitis.

Nat Rev Dis Primers 2018 06 21;4(1). Epub 2018 Jun 21.

Paediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin, Ireland.

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http://www.nature.com/articles/s41572-018-0001-z
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http://dx.doi.org/10.1038/s41572-018-0001-zDOI Listing
June 2018

Low vitamin D deficiency in Irish toddlers despite northerly latitude and a high prevalence of inadequate intakes.

Eur J Nutr 2018 Mar 26;57(2):783-794. Epub 2016 Dec 26.

Cork Centre for Vitamin D and Nutrition Research, School of Food and Nutritional Sciences, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1007/s00394-016-1368-9DOI Listing
March 2018

Variation in iodine food composition data has a major impact on estimates of iodine intake in young children.

Eur J Clin Nutr 2018 03 9;72(3):410-419. Epub 2017 Nov 9.

Cork Centre for Vitamin D and Nutrition Research, School of Food and Nutritional Sciences, College of Science, Engineering and Food Science, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1038/s41430-017-0030-9DOI Listing
March 2018

Iron status, body size, and growth in the first 2 years of life.

Matern Child Nutr 2018 01 27;14(1). Epub 2017 Apr 27.

Cork Centre for Vitamin D and Nutrition Research, School of Food and Nutritional Sciences, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1111/mcn.12458DOI Listing
January 2018

When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council.

J Am Acad Dermatol 2017 Oct 10;77(4):623-633. Epub 2017 Aug 10.

Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2017.06.042DOI Listing
October 2017

Methotrexate for Severe Childhood Atopic Dermatitis: Clinical Experience in a Tertiary Center.

Pediatr Dermatol 2017 Sep 21;34(5):528-534. Epub 2017 Jul 21.

Pediatric Dermatology Department, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland.

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http://dx.doi.org/10.1111/pde.13209DOI Listing
September 2017

Microcytosis is associated with low cognitive outcomes in healthy 2-year-olds in a high-resource setting.

Br J Nutr 2017 Sep;118(5):360-367

2The Irish Centre for Fetal and Neonatal Translational Research (INFANT),University College Cork,Cork,Republic of Ireland.

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http://dx.doi.org/10.1017/S0007114517001945DOI Listing
September 2017

Iron intakes and status of 2-year-old children in the Cork BASELINE Birth Cohort Study.

Matern Child Nutr 2017 07 9;13(3). Epub 2016 Aug 9.

Cork Centre for Vitamin D and Nutrition Research, School of Food and Nutritional Sciences, University College Cork, Ireland.

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http://dx.doi.org/10.1111/mcn.12320DOI Listing
July 2017

Mathematical modeling of atopic dermatitis reveals "double-switch" mechanisms underlying 4 common disease phenotypes.

J Allergy Clin Immunol 2017 Jun 5;139(6):1861-1872.e7. Epub 2016 Dec 5.

Department of Bioengineering, Imperial College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.10.026DOI Listing
June 2017

Body Composition within the First 3 Months: Optimized Correction for Length and Correlation with BMI at 2 Years.

Horm Res Paediatr 2016 25;86(3):178-187. Epub 2016 Aug 25.

Division of Endocrinology and Diabetes, The Children's Hospital of Philadelphia, Philadelphia, Pa., USA.

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http://dx.doi.org/10.1159/000448659DOI Listing
April 2017

Vitamin D metabolite concentrations in umbilical cord blood serum and associations with clinical characteristics in a large prospective mother-infant cohort in Ireland.

J Steroid Biochem Mol Biol 2017 03 19;167:162-168. Epub 2016 Dec 19.

Irish Centre for Fetal and Neonatal Translational Research [INFANT], University College Cork, Ireland; Department of Pediatrics and Child Health, University College Cork, Ireland.

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http://dx.doi.org/10.1016/j.jsbmb.2016.12.006DOI Listing
March 2017

Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year.

J Allergy Clin Immunol 2017 01 5;139(1):166-172. Epub 2016 Sep 5.

Clinical Medicine, Trinity College Dublin, Dublin, Ireland; National Children's Research Centre, Our Lady's Children's Hospital Crumlin, Dublin, Ireland; Paediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin, Ireland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749163089
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http://dx.doi.org/10.1016/j.jaci.2016.07.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207796PMC
January 2017

Access to Genetic Diagnostics for Genodermatoses: Who Should Get Tested? Why? Who Pays?

Pediatr Dermatol 2017 Jan 16;34(1):105-108. Epub 2016 Dec 16.

Paediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin, Ireland.

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http://dx.doi.org/10.1111/pde.13041DOI Listing
January 2017

Atopic Dermatitis According to GARP: New Mechanistic Insights in Disease Pathogenesis.

J Invest Dermatol 2016 12;136(12):2340-2341

Department of Clinical Medicine, Trinity College, Dublin, Ireland; National Children's Research Centre, Our Lady's Children's Hospital Crumlin, Dublin, Ireland; Department of Paediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.08.020DOI Listing
December 2016

Cord blood leptin and gains in body weight and fat mass during infancy.

Eur J Endocrinol 2016 Nov 15;175(5):403-10. Epub 2016 Aug 15.

Cork Centre for Vitamin D and Nutrition ResearchSchool of Food and Nutritional Sciences The Irish Centre for Fetal and Neonatal Translational Research (INFANT)

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http://dx.doi.org/10.1530/EJE-16-0431DOI Listing
November 2016

Update on Epidemiology, Diagnosis, and Disease Course of Atopic Dermatitis.

Semin Cutan Med Surg 2016 Jun;35(5 Suppl):S84-8

Professor of Dermatology and Pediatrics University of California San Diego School of Medicine Fellowship Program Director Pediatric and Adolescent Dermatology Rady Children's Hospital San Diego, California.

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http://dx.doi.org/10.12788/j.sder.2016.041DOI Listing
June 2016

Review of Critical Issues in the Pathogenesis of Atopic Dermatitis.

Semin Cutan Med Surg 2016 Jun;35(5 Suppl):S89-91

Professor of Dermatology Director of Clinical Studies Oregon Health and Science University Department of Dermatology Portland, Oregon.

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http://dx.doi.org/10.12788/j.sder.2016.042DOI Listing
June 2016

Assessing the New and Emerging Treatments for Atopic Dermatitis.

Semin Cutan Med Surg 2016 Jun;35(5 Suppl):S92-6

Professor of Dermatology Trinity College Dublin Attending Dermatologist Our Lady's Children's Hospital Crumlin St. James's Hospital Dublin, Ireland.

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http://dx.doi.org/10.12788/j.sder.2016.043DOI Listing
June 2016

The Changing Paradigm of Atopic Dermatitis Therapy.

Semin Cutan Med Surg 2016 06;35(5 Suppl):S97-9

Professor of Dermatology and Pediatrics Chief, Pediatric and Adolescent Dermatology University of California San Diego School of Medicine Rady Children's Hospital San Diego, California.

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http://dx.doi.org/10.12788/j.sder.2016.044DOI Listing
June 2016

Skin barrier impairment at birth predicts food allergy at 2 years of age.

J Allergy Clin Immunol 2016 Apr;137(4):1111-1116.e8

Paediatrics and Child Health, University College Cork, Cork, Ireland; National Children's Research Centre, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.12.1312DOI Listing
April 2016

Too Much, Too Little or Just Enough: A Goldilocks Effect for IL-13 and Skin Barrier Regulation?

J Invest Dermatol 2016 Mar;136(3):561-564

National Children's Research Centre, Our Lady's Children's Hospital Crumlin, Dublin, Ireland; Department of Paediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin, Ireland; Department of Clinical Medicine, Trinity College Dublin, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2015.12.025DOI Listing
March 2016

Spontaneous atopic dermatitis is mediated by innate immunity, with the secondary lung inflammation of the atopic march requiring adaptive immunity.

J Allergy Clin Immunol 2016 Feb 20;137(2):482-91. Epub 2015 Aug 20.

Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland; National Children's Research Centre, Our Lady's Children's Hospital, Dublin, Ireland; Institute of Molecular Medicine, St James's Hospital, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.06.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735016PMC
February 2016

Neonatal adiposity increases the risk of atopic dermatitis during the first year of life.

J Allergy Clin Immunol 2016 Jan 17;137(1):108-117. Epub 2015 Jul 17.

Vitamin D Research Group, School of Food and Nutritional Sciences, University College Cork, Cork, Ireland; Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Cork, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.05.035DOI Listing
January 2016

Filaggrin breakdown products determine corneocyte conformation in patients with atopic dermatitis.

J Allergy Clin Immunol 2015 Dec 11;136(6):1573-1580.e2. Epub 2015 Jun 11.

Coronel Institute of Occupational Health, Academic Medical Center, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.04.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669308PMC
December 2015

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.

Authors:
Lavinia Paternoster Marie Standl Johannes Waage Hansjörg Baurecht Melanie Hotze David P Strachan John A Curtin Klaus Bønnelykke Chao Tian Atsushi Takahashi Jorge Esparza-Gordillo Alexessander Couto Alves Jacob P Thyssen Herman T den Dekker Manuel A Ferreira Elisabeth Altmaier Patrick Ma Sleiman Feng Li Xiao Juan R Gonzalez Ingo Marenholz Birgit Kalb Maria Pino Yanes Cheng-Jian Xu Lisbeth Carstensen Maria M Groen-Blokhuis Cristina Venturini Craig E Pennell Sheila J Barton Albert M Levin Ivan Curjuric Mariona Bustamante Eskil Kreiner-Møller Gabrielle A Lockett Jonas Bacelis Supinda Bunyavanich Rachel A Myers Anja Matanovic Ashish Kumar Joyce Y Tung Tomomitsu Hirota Michiaki Kubo Wendy L McArdle A J Henderson John P Kemp Jie Zheng George Davey Smith Franz Rüschendorf Anja Bauerfeind Min Ae Lee-Kirsch Andreas Arnold Georg Homuth Carsten O Schmidt Elisabeth Mangold Sven Cichon Thomas Keil Elke Rodríguez Annette Peters Andre Franke Wolfgang Lieb Natalija Novak Regina Fölster-Holst Momoko Horikoshi Juha Pekkanen Sylvain Sebert Lise L Husemoen Niels Grarup Johan C de Jongste Fernando Rivadeneira Albert Hofman Vincent Wv Jaddoe Suzanne Gma Pasmans Niels J Elbert André G Uitterlinden Guy B Marks Philip J Thompson Melanie C Matheson Colin F Robertson Janina S Ried Jin Li Xian Bo Zuo Xiao Dong Zheng Xian Yong Yin Liang Dan Sun Maeve A McAleer Grainne M O'Regan Caoimhe Mr Fahy Linda E Campbell Milan Macek Michael Kurek Donglei Hu Celeste Eng Dirkje S Postma Bjarke Feenstra Frank Geller Jouke Jan Hottenga Christel M Middeldorp Pirro Hysi Veronique Bataille Tim Spector Carla Mt Tiesler Elisabeth Thiering Badri Pahukasahasram James J Yang Medea Imboden Scott Huntsman Natàlia Vilor-Tejedor Caroline L Relton Ronny Myhre Wenche Nystad Adnan Custovic Scott T Weiss Deborah A Meyers Cilla Söderhäll Erik Melén Carole Ober Benjamin A Raby Angela Simpson Bo Jacobsson John W Holloway Hans Bisgaard Jordi Sunyer Nicole M Probst Hensch L Keoki Williams Keith M Godfrey Carol A Wang Dorret I Boomsma Mads Melbye Gerard H Koppelman Deborah Jarvis Wh Irwin McLean Alan D Irvine Xue Jun Zhang Hakon Hakonarson Christian Gieger Esteban G Burchard Nicholas G Martin Liesbeth Duijts Allan Linneberg Marjo-Riitta Jarvelin Markus M Noethen Susanne Lau Norbert Hübner Young-Ae Lee Mayumi Tamari David A Hinds Daniel Glass Sara J Brown Joachim Heinrich David M Evans Stephan Weidinger

Nat Genet 2015 Dec 19;47(12):1449-1456. Epub 2015 Oct 19.

Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1038/ng.3424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753676PMC
December 2015

Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin.

J Allergy Clin Immunol 2015 Nov 12;136(5):1268-76. Epub 2015 Jun 12.

Clinical Medicine, Trinity College Dublin, Dublin, Ireland; Pediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin, Ireland; National Children's Research Centre, Our Lady's Children's Hospital Crumlin, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649901PMC
November 2015

Adherence with early infant feeding and complementary feeding guidelines in the Cork BASELINE Birth Cohort Study.

Public Health Nutr 2015 Oct 18;18(15):2864-73. Epub 2015 Feb 18.

1Vitamin D Research Group,School of Food and Nutritional Science,University College Cork,Cork,Republic of Ireland.

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http://dx.doi.org/10.1017/S136898001500018XDOI Listing
October 2015

Kasabach-Merritt syndrome, kaposiform haemangioendothelioma and platelet blockade.

Br J Haematol 2015 Oct 26;171(1):11. Epub 2015 Jun 26.

Department of Haematology, Our Lady's Children's Hospital, Dublin 12, Ireland.

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http://dx.doi.org/10.1111/bjh.13558DOI Listing
October 2015

Recent advances in the pathobiology and management of Kasabach-Merritt phenomenon.

Br J Haematol 2015 Oct 30;171(1):38-51. Epub 2015 Jun 30.

Department of Haematology, Our Lady's Children's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1111/bjh.13557DOI Listing
October 2015

Expanding the clinical spectrum of hereditary fibrosing poikiloderma with tendon contractures, myopathy and pulmonary fibrosis due to FAM111B mutations.

Orphanet J Rare Dis 2015 Oct 15;10:135. Epub 2015 Oct 15.

CHU Nantes, Service de Génétique Médicale, Unité de Génétique Moléculaire, 9 quai Moncousu, 44093, Nantes CEDEX 1, France.

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http://link.springer.com/content/pdf/10.1186%2Fs13023-015-03
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http://www.ojrd.com/content/10/1/135
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http://dx.doi.org/10.1186/s13023-015-0352-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608180PMC
October 2015

DOCK8 primary immunodeficiency syndrome.

Lancet 2015 Sep 20;386(9997):982. Epub 2015 Mar 20.

National Children's Research Centre, Dublin, Ireland; Department of Clinical Medicine, Trinity College Dublin, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(14)62039-0DOI Listing
September 2015

Cohort profile: The Cork BASELINE Birth Cohort Study: Babies after SCOPE: Evaluating the Longitudinal Impact on Neurological and Nutritional Endpoints.

Int J Epidemiol 2015 Jun 7;44(3):764-75. Epub 2014 Aug 7.

Vitamin D Research Group, School of Food and Nutritional Science, Irish Centre for Fetal and Neonatal Translational Research and

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http://dx.doi.org/10.1093/ije/dyu157DOI Listing
June 2015

Ichthyosis prematurity syndrome: a case report and review of known mutations.

Pediatr Dermatol 2014 Jul-Aug;31(4):517-8. Epub 2014 May 29.

Department of Paediatric Dermatology, Children's University Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1111/pde.12320DOI Listing
May 2015

Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year.

J Allergy Clin Immunol 2015 Apr 22;135(4):930-5.e1. Epub 2015 Jan 22.

National Children's Research Centre, Dublin, Ireland; Paediatric Dermatology, Our Lady's Children's Hospital, Dublin, Ireland; Clinical Medicine, Trinity College Dublin, Dublin, Ireland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749140179
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http://dx.doi.org/10.1016/j.jaci.2014.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382348PMC
April 2015

Use of ruxolitinib to successfully treat chronic mucocutaneous candidiasis caused by gain-of-function signal transducer and activator of transcription 1 (STAT1) mutation.

J Allergy Clin Immunol 2015 Feb;135(2):551-3

Dermatology, St James's Hospital, Dublin, Ireland; National Children's Research Centre, Our Lady's Children's Hospital, Dublin, Ireland; Department of Clinical Medicine, Trinity College Dublin, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2014.12.1867DOI Listing
February 2015

A longitudinal study of skin barrier function in pregnancy and the postnatal period.

Obstet Med 2014 Dec 4;7(4):156-9. Epub 2014 Sep 4.

The Irish Centre for Fetal and Neonatal Translational Research (INFANT), University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1177/1753495X14547428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934992PMC
December 2014

Second International Conference on a classification of ectodermal dysplasias: development of a multiaxis model.

Am J Med Genet A 2014 Oct 3;164A(10):2482-9. Epub 2014 Apr 3.

Medical University of South Carolina, College of Dental Medicine, Division Craniofacial Genetics, Charleston, South Carolina.

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http://dx.doi.org/10.1002/ajmg.a.36507DOI Listing
October 2014

Use of systemic corticosteroids in management of a large congenital haemangioma of the scalp.

Pediatr Dermatol 2013 Nov-Dec;30(6):e121-4. Epub 2012 Sep 25.

Department of Paediatric Dermatology, Our Lady's Children's Hospital, Dublin, IrelandPaediatric Radiology, Our Lady's Children's Hospital, Dublin, IrelandDepartment of Paediatrics and Child Health, University College Cork, Cork, IrelandDepartment of Obstetrics, University College Cork, Cork, IrelandDepartment of Dermatology, South Infirmary Victoria Hospital, Cork, Ireland.

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http://dx.doi.org/10.1111/j.1525-1470.2012.01795.xDOI Listing
August 2014

Newborn transepidermal water loss values: a reference dataset.

Pediatr Dermatol 2013 Nov-Dec;30(6):712-6. Epub 2013 Mar 5.

Department of Paediatrics and Child Health, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1111/pde.12106DOI Listing
August 2014

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis.

J Allergy Clin Immunol 2014 Jul 28;134(1):82-91. Epub 2014 May 28.

Centre for Dermatology and Genetic Medicine, Division of Molecular Medicine, Colleges of Life Sciences and Medicine, Dentistry & Nursing, University of Dundee, Dundee, United Kingdom; National Children's Research Centre, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2014.04.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090750PMC
July 2014

siRNA silencing of the mutant keratin 12 allele in corneal limbal epithelial cells grown from patients with Meesmann's epithelial corneal dystrophy.

Invest Ophthalmol Vis Sci 2014 May 6;55(5):3352-60. Epub 2014 May 6.

School of Biomedical Sciences, University of Ulster, Coleraine, Northern Ireland, United Kingdom Dermatology and Genetic Medicine, Colleges of Life Sciences and Medicine, Dentistry & Nursing, University of Dundee, Dundee, Scotland, United Kingdom Centre for Regenerative Medicine, Stefano Ferrari, University of Modena and Reggio Emilia, Modena, Italy.

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http://dx.doi.org/10.1167/iovs.13-12957DOI Listing
May 2014

Crossing barriers; restoring barriers? Filaggrin protein replacement takes a bow.

Authors:
Alan D Irvine

J Invest Dermatol 2014 Feb;134(2):313-314

Department of Paediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin, Ireland; National Children's Research Centre, Our Lady's Children's Hospital Crumlin, Dublin, Ireland; Clinical Medicine, Trinity College Dublin, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1038/jid.2013.506DOI Listing
February 2014

Kaposi sarcoma in an patient with atopic dermatitis treated with ciclosporin.

BMJ Case Rep 2013 Nov 21;2013. Epub 2013 Nov 21.

Department of Dermatology, St James's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1136/bcr-2013-202171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841426PMC
November 2013

Systemic therapies for severe atopic dermatitis in children and adults.

J Allergy Clin Immunol 2013 Sep;132(3):774-774.e6

National Children's Research Centre, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland; Department of Pediatric Dermatology, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland; Department of Clinical Medicine, Trinity College, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2013.03.016DOI Listing
September 2013

Childhood eczema and the importance of the physical environment.

J Invest Dermatol 2013 Jul;133(7):1706-9

Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.

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http://dx.doi.org/10.1038/jid.2013.128DOI Listing
July 2013

Old King coal - molecular mechanisms underlying an ancient treatment for atopic eczema.

J Clin Invest 2013 Feb 25;123(2):551-3. Epub 2013 Jan 25.

Centre for Dermatology and Genetic Medicine, Division of Molecular Medicine, College of Life Sciences and Medicine, Dentistry and Nursing, University of Dundee, Dow Street, Dundee DD1 5EH, United Kingdom.

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http://dx.doi.org/10.1172/JCI67438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561843PMC
February 2013

The multifunctional role of filaggrin in allergic skin disease.

J Allergy Clin Immunol 2013 Feb;131(2):280-91

National Children's Research Centre, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland.

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http://dx.doi.org/10.1016/j.jaci.2012.12.668DOI Listing
February 2013

Heritable Filaggrin Disorders: The Paradigm of Atopic Dermatitis.

J Invest Dermatol 2012 Nov;132 Suppl 3:E20-1

National Children's Research Centre, Dublin, Ireland; Department of Paediatric Dermatology, Our Lady's Children's Hospital, Dublin, Ireland; Department of Clinical Medicine, Trinity College Dublin, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1038/skinbio.2012.6DOI Listing
November 2012

Heritable filaggrin disorders: the paradigm of atopic dermatitis.

J Invest Dermatol 2012 Nov 15;132(E1):E20-1. Epub 2012 Nov 15.

Dermatology and Genetic Medicine, College of Life Sciences and College of Medicine, Dentistry and Nursing, University of Dundee, Dundee, UK.

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http://dx.doi.org/10.1038/skinbio.2012.6DOI Listing
November 2012

Methylenetetrahydrofolate reductase (MTHFR) deficiency presenting as a rash.

Am J Med Genet A 2012 Sep 27;158A(9):2254-7. Epub 2012 Jul 27.

National Centre for Inherited Metabolic Disorders, Children's University Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1002/ajmg.a.35479DOI Listing
September 2012

Double trouble: homozygous dominant mutations and hair loss in pachyonychia congenita.

Authors:
Alan D Irvine

J Invest Dermatol 2012 Jul;132(7):1757-9

National Children's Research Centre and Paediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin, Ireland.

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http://dx.doi.org/10.1038/jid.2012.121DOI Listing
July 2012

Skin involvement in Down syndrome transient abnormal myelopoiesis.

Br J Haematol 2012 May 3;157(3):280. Epub 2012 Mar 3.

Departments of Haematology, Our Ladies Children's Hospital, Crumlin, Dublin, Ireland.

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http://dx.doi.org/10.1111/j.1365-2141.2012.09079.xDOI Listing
May 2012