Publications by authors named "Alain Schweitzer"

14Publications

Preclinical antitumor activity of the orally available heat shock protein 90 inhibitor NVP-BEP800.

Authors:
Andrew J Massey Joseph Schoepfer Paul A Brough Josef Brueggen Patrick Chène Martin J Drysdale Ulrike Pfaar Thomas Radimerski Stephan Ruetz Alain Schweitzer Mike Wood Carlos Garcia-Echeverria Michael Rugaard Jensen

Mol Cancer Ther 2010 Apr 6;9(4):906-19. Epub 2010 Apr 6.

Novartis Institutes for BioMedical Research, Novartis Pharma AG, Klybeckstrasse 141, WKL-125.2.42, CH-4057 Basel, Switzerland.

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April 2010

Autoradiography, MALDI-MS, and SIMS-MS imaging in pharmaceutical discovery and development.

Authors:
Eric G Solon Alain Schweitzer Markus Stoeckli Brendan Prideaux

AAPS J 2010 Mar 17;12(1):11-26. Epub 2009 Nov 17.

QPS, LLC, Newark, Delaware 19702, USA.

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March 2010

Pharmacokinetics, distribution, metabolism, and excretion of deferasirox and its iron complex in rats.

Authors:
Gerard J M Bruin Thomas Faller Hansjörg Wiegand Alain Schweitzer Hanspeter Nick Josef Schneider K-Olaf Boernsen Felix Waldmeier

Drug Metab Dispos 2008 Dec 5;36(12):2523-38. Epub 2008 Sep 5.

Novartis Pharma AG, Drug Metabolism and Pharmacokinetics, Novartis Campus, Basel, Switzerland.

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December 2008

Biodistribution and plasma protein binding of zoledronic acid.

Authors:
H Markus Weiss Ulrike Pfaar Alain Schweitzer Hansjörg Wiegand Andrej Skerjanec Horst Schran

Drug Metab Dispos 2008 Oct 14;36(10):2043-9. Epub 2008 Jul 14.

Novartis Pharma AG, DMPK, WSJ-210.4.25, CH-4002 Basel, Switzerland.

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October 2008

Pimecrolimus: skin disposition after topical administration in minipigs in vivo and in human skin in vitro.

Authors:
Hans-Peter Gschwind Felix Waldmeier Markus Zollinger Alain Schweitzer Maximilian Grassberger

Eur J Pharm Sci 2008 Jan 22;33(1):9-19. Epub 2007 Sep 22.

Novartis Pharma AG, Exploratory Development/DMPK, WKL-135.2.25, CH-4002 Basel, Switzerland.

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January 2008

Imaging of a beta-peptide distribution in whole-body mice sections by MALDI mass spectrometry.

Authors:
Markus Stoeckli Dieter Staab Alain Schweitzer James Gardiner Dieter Seebach

J Am Soc Mass Spectrom 2007 Nov 16;18(11):1921-4. Epub 2007 Aug 16.

Novartis Institutes for BioMedical Research, Basel, Switzerland.

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November 2007

Brain penetration of the oral immunomodulatory drug FTY720 and its phosphorylation in the central nervous system during experimental autoimmune encephalomyelitis: consequences for mode of action in multiple sclerosis.

Authors:
Carolyn A Foster Laurence M Howard Alain Schweitzer Elke Persohn Peter C Hiestand Balázs Balatoni Roland Reuschel Christian Beerli Manuela Schwartz Andreas Billich

J Pharmacol Exp Ther 2007 Nov 6;323(2):469-75. Epub 2007 Aug 6.

Novartis Institutes for BioMedical Research, Vienna, Austria.

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November 2007

ADME investigations of unnatural peptides: distribution of a 14C-labeled beta 3-octaarginine in rats.

Authors:
H Markus Weiss Bernard Wirz Alain Schweitzer René Amstutz Maria I Rodriguez Perez Hendrik Andres Yves Metz James Gardiner Dieter Seebach

Chem Biodivers 2007 Jul;4(7):1413-37

Drug Metabolism and Pharmacokinetics, Novartis Pharma AG, Postfach, CH-4002 Basel.

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July 2007

Pharmacokinetic investigation of a 14C-labelled beta 3/alpha tetrapeptide in rats.

Authors:
Hansjörg Wiegand Bernard Wirz Alain Schweitzer Gerhard Gross Maria I Rodriguez Perez Hendrik Andres Thierry Kimmerlin Magnus Rueping Dieter Seebach

Chem Biodivers 2004 Nov;1(11):1812-28

Preclinical Safety Europe, Novartis Pharma AG, Postfach, CH-4002 Basel.

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November 2004

Pimecrolimus: absorption, distribution, metabolism, and excretion in healthy volunteers after a single oral dose and supplementary investigations in vitro.

Authors:
Markus Zollinger Felix Waldmeier Stefan Hartmann Gerhard Zenke Alfred G Zimmerlin Ulrike Glaenzel Jean-Pierre Baldeck Alain Schweitzer Stephane Berthier Thomas Moenius Maximilian A Grassberger

Drug Metab Dispos 2006 May 7;34(5):765-74. Epub 2006 Feb 7.

Novartis Pharma AG, WKL-135.2.21, P.O. box, CH-4002 Basel, Switzerland.

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May 2006

A locally active antiinflammatory macrolide (MLD987) for inhalation therapy of asthma.

Authors:
Rene Hersperger Karl-Heinz Buchheit Salvatore Cammisuli Albert Enz Olivier Lohse Monique Ponelle Walter Schuler Alain Schweitzer Christoph Walker Hartmut Zehender Gerhard Zenke Alfred G Zimmerlin Markus Zollinger Lazzaro Mazzoni John R Fozard

J Med Chem 2004 Sep;47(20):4950-7

Novartis Institutes for BioMedical Research and Novartis Pharma Development, CH-4002 Basle, Switzerland.

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September 2004

Removal of anti-Galalpha1,3Gal xenoantibodies with an injectable polymer.

Authors:
Andreas G Katopodis Richard G Warner Rudolf O Duthaler Markus B Streiff Armin Bruelisauer Olivier Kretz Birgit Dorobek Elke Persohn Hendrik Andres Alain Schweitzer Gebhard Thoma Willy Kinzy Valerie F J Quesniaux Emanuele Cozzi Hugh F S Davies Rafael Mañez David White

J Clin Invest 2002 Dec;110(12):1869-77

Novartis Institutes for Biomedical Research, Transplantation Research, Basel, Switzerland.

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December 2002

The outstanding metabolic stability of a 14C-labeled beta-nonapeptide in rats--in vitro and in vivo pharmacokinetic studies.

Authors:
Hansjörg Wiegand Bernard Wirz Alain Schweitzer Gian P Camenisch Maria I Rodriguez Perez Gerhard Gross Ralph Woessner Rolf Voges Per I Arvidsson Jens Frackenpohl Dieter Seebach

Biopharm Drug Dispos 2002 Sep;23(6):251-62

Drug Metabolism & Pharmacokinetics, Novartis Pharma AG, Postfach, CH-4002 Basel, Switzerland.

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September 2002

(18)F-FDG and (18)F-FET uptake in experimental soft tissue infection.

Authors:
Achim H Kaim Bruno Weber Michael O Kurrer Gerrit Westera Alain Schweitzer Jochen Gottschalk Gustav K von Schulthess Alfred Buck

Eur J Nucl Med Mol Imaging 2002 May 6;29(5):648-54. Epub 2002 Mar 6.

Nuclear Medicine, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.

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May 2002