Alain Ruffion

Alain Ruffion

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Alain Ruffion

Publications by authors named "Alain Ruffion"

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Prostate brachytherapy under hypnosedation: A prospective evaluation.

Brachytherapy 2019 Jan - Feb;18(1):22-28. Epub 2018 Nov 10.

Department of Anesthesiology, Centre Hospitalier Lyon Sud, Pierre-Benite, France.

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https://linkinghub.elsevier.com/retrieve/pii/S15384721183054
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http://dx.doi.org/10.1016/j.brachy.2018.10.004DOI Listing
April 2019

Robot-assisted Partial Nephrectomy: Is Routine Urinary Catheterization Still Mandatory in the Era of Enhanced Recovery?

Urology 2019 02 6;124:148-153. Epub 2018 Oct 6.

Department of Urology, Lyon Sud-Pierre Bénite Teaching Hospital, Lyon, France.

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http://dx.doi.org/10.1016/j.urology.2018.09.028DOI Listing
February 2019

A prospective, multicenter study of a novel, miniaturized rechargeable sacral neuromodulation system: 12-month results from the RELAX-OAB study.

Neurourol Urodyn 2019 Feb 28;38(2):689-695. Epub 2018 Dec 28.

Department of Uro-Neurology, National Hospital of Neurology and Neurosurgery, London, United Kingdom.

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http://doi.wiley.com/10.1002/nau.23892
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http://dx.doi.org/10.1002/nau.23892DOI Listing
February 2019

First Outcomes of the ZSI 475 FtM, a Specific Prosthesis Designed for Phalloplasty.

J Sex Med 2019 Feb 9;16(2):316-322. Epub 2019 Jan 9.

Department of Urology, Centre hospitalier Lyon-Sud, Hospices Civils de Lyon, Pierre-Bénite, France; Hospices Civils de Lyon, Pôle IMER, Universite de Lyon, Lyon, France. Electronic address:

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http://dx.doi.org/10.1016/j.jsxm.2018.11.013DOI Listing
February 2019

Characterization of Prostate Cancer with Gleason Score of at Least 7 by Using Quantitative Multiparametric MR Imaging: Validation of a Computer-aided Diagnosis System in Patients Referred for Prostate Biopsy.

Radiology 2018 05 22;287(2):525-533. Epub 2018 Jan 22.

From Hanoi Medical University Hospital, Hanoi, Vietnam (A.H.D.); Inserm, U1032, LabTau, Lyon, France (A.H.D., R.S., S.C., O.R.); CNRS, UMR 5553, Grenoble, France (C.M.); Université Joseph Fourier, Laboratoire d'Ecologie Alpine, Grenoble, France (C.M.); Hospices Civils de Lyon, Department of Urinary and Vascular Imaging, Hôpital Edouard Herriot, Lyon, France (P.C.M., F.B., G.P., O.R.); Université de Lyon, Lyon, France; Université Lyon 1, Faculté de Médecine Lyon Est, Lyon, France (P.C.M., S.C., M.C., O.R.); Hospices Civils de Lyon, Department of Pathology, Hôpital Edouard Herriot, Lyon, France (F.M.L.); Hospices Civils de Lyon, Department of Urology, Centre Hospitalier Lyon Sud, Pierre Bénite, France (A.R.); and Hospices Civils de Lyon, Department of Urology, Hôpital Edouard Herriot, Lyon, France (S.C., M.C.).

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http://dx.doi.org/10.1148/radiol.2017171265DOI Listing
May 2018

MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis.

N Engl J Med 2018 May 18;378(19):1767-1777. Epub 2018 Mar 18.

From University College London (UCL) and UCL Hospitals NHS Foundation Trust (V.K., C.A., F.G., A.F., S.M., S.P., M.E., C.M.M.), London North West Healthcare NHS Trust (G.H.), Whittington Health NHS Trust (M.G.), Royal Free London NHS Foundation Trust (P.B.S.), and UCL Surgical and Interventional Trials Unit (N.R.W., C.B.-G.), London, Hampshire Hospitals NHS Foundation Trust, Basingstoke (R.G.H.), Princess Alexandra Hospital NHS Trust, Harlow (J.V.), and the Institute of Applied Health Research and the NIHR Birmingham Biomedical Research Centre, University of Birmingham, Birmingham (J.D., Y.T.) - all in the United Kingdom; Helsinki University and Helsinki University Hospital, Helsinki (A.S.R.), and Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu (M.H.V.) - all in Finland; Centro de Urología, Buenos Aires (M.B.); Sapienza University, Rome (V.P.), and IRCCS Ospedale San Raffaele and Vita-Salute San Raffaele University, Milan (A.B.) - all in Italy; Mayo Clinic, Rochester, MN (L.A.M.); Martini Klinik, Hamburg (L.B.), University Hospital Essen, Essen (B.A.H.), and University Hospital Heidelberg, Heidelberg (B.A.H.) - all in Germany; Erasmus University Medical Center, Rotterdam (M.J.R.), and Radboud University Medical Center, Nijmegen (W.V.) - both in the Netherlands; University of Chicago, Chicago (S.E.); Université de Lille and Centre Hospitalier Universitaire Lille, Lille (A.V.), Université de Bordeaux and Bordeaux Pellegrin University Hospital, Bordeaux (G.R.), and Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud (A.R.), and Hospices Civils de Lyon of the Hôpital Edouard Herriot (S.C.), Lyon - all in France; Jewish General Hospital, Montreal (F.B.), and Sunnybrook Health Sciences Centre, Toronto (L.K.) - both in Canada; Ghent University Hospital, Ghent, Belgium (G.M.V.); University Hospital Bern, Bern, Switzerland (S.B.); Weill Cornell Medicine, New York-Presbyterian Hospital (J.C.H., D.M.), and New York University Langone Medical Center (S.S.T.), New York; National Institutes of Health, Bethesda, MD (P.P.); and the University of Southern California Institute of Urology, Keck School of Medicine, Los Angeles (I.G.).

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http://dx.doi.org/10.1056/NEJMoa1801993DOI Listing
May 2018

Male Sexuality, Fertility, and Urinary Continence in Bladder Exstrophy-Epispadias Complex.

J Sex Med 2018 Mar;15(3):314-323

Service d'urologie, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Université Claude-Bernard-Lyon 1-France.

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http://dx.doi.org/10.1016/j.jsxm.2018.01.004DOI Listing
March 2018

Three month clinical results with a rechargeable sacral neuromodulation system for the treatment of overactive bladder.

Neurourol Urodyn 2018 02 5;37(S2):S9-S16. Epub 2018 Jan 5.

Department of Uro-Neurology, National Hospital of Neurology and Neurosurgery, London, United Kingdom.

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http://dx.doi.org/10.1002/nau.23465DOI Listing
February 2018

Programming settings and recharge interval in a prospective study of a rechargeable sacral neuromodulation system for the treatment of overactive bladder.

Neurourol Urodyn 2018 02 16;37(S2):S17-S22. Epub 2018 Jan 16.

Department of Uro-Neurology, National Hospital of Neurology and Neurosurgery, London, United Kingdom.

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http://dx.doi.org/10.1002/nau.23476DOI Listing
February 2018

Prospective evaluation of a specific technique of sexual function preservation in external beam radiotherapy for prostate cancer.

Br J Radiol 2017 Oct 27;90(1078):20160877. Epub 2017 Jul 27.

1 Department of Radiation Oncology, Centre Hospitalier Lyon Sud, Pierre-Benite, France.

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http://dx.doi.org/10.1259/bjr.20160877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853354PMC
October 2017

Non-invasive prediction of recurrence in bladder cancer by detecting somatic TERT promoter mutations in urine.

Br J Cancer 2017 Aug 6;117(4):583-587. Epub 2017 Jul 6.

Hospices Civils de Lyon, Service d'Urologie, Centre Hospitalier Lyon Sud, Pierre Bénite Cedex 69495, France.

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http://dx.doi.org/10.1038/bjc.2017.210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558690PMC
August 2017

Genitourinary injuries after traffic accidents: Analysis of a registry of 162,690 victims.

J Trauma Acute Care Surg 2017 06;82(6):1087-1093

From the Department of Urology (J.E.T., P.P., A.R.), Centre Hospitalier Lyon Sud, Lyon, France; UMR Epidémiologique et de Surveillance Transport Travail Environnement. IFSTTAR (French Institute of Science and Technology for Transport, Spatial Planning, Development and Networks) (B.G., A.N.), Université Lyon1, Universités de Lyon, Lyon, France; and Department of Urology (L.C.J.), The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1097/TA.0000000000001448DOI Listing
June 2017

Surgical Outcomes of Erectile Implants After Phalloplasty: Retrospective Analysis of 95 Procedures.

J Sex Med 2016 Nov 29;13(11):1758-1764. Epub 2016 Sep 29.

Department of Urology, Centre hospitalier Lyon-Sud, Hospices Civils de Lyon, Pierre-Bénite Cedex, France; Université Lyon 1 Claude Bernard, Faculté de Médecine Lyon-Sud, Oullins Cedex, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S17436095163042
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http://dx.doi.org/10.1016/j.jsxm.2016.09.013DOI Listing
November 2016

Quantitative Analysis of Prostate Multiparametric MR Images for Detection of Aggressive Prostate Cancer in the Peripheral Zone: A Multiple Imager Study.

Radiology 2016 07 9;280(1):117-27. Epub 2016 Feb 9.

From INSERM, U1032, LabTau, Lyon, France (A.H.D., R.S., J.L., F.B., S.C., O.R.); CNRS, UMR 5553, BP 53, Grenoble, France (C.M.); Laboratoire d'Ecologie Alpine, Université Joseph Fourier, Grenoble, France (C.M.); Department of Urinary and Vascular Imaging (F.B., O.R.), Department of Pathology (F.M.L.), and Department of Urology (S.C., M.C.), Hospices Civils de Lyon, Hôpital Edouard Herriot, Pavillon P Radio, 5 place d'Arsonval, Lyon 69003, France; Université Lyon 1, Faculté de Médecine Lyon Est, Lyon, France (F.B., S.C., M.C., O.R.); and Department of Urology, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre Bénite, France (A.R.).

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http://dx.doi.org/10.1148/radiol.2016151406DOI Listing
July 2016

Identification of Most Aggressive Carcinoma Among Patients Diagnosed With Prostate Cancer Using Mathematical Modeling of Prostate-Specific Antigen Increases.

Clin Genitourin Cancer 2016 Jun 18;14(3):210-217.e1. Epub 2015 Dec 18.

Département d'urologie, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, Lyon, France.

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http://dx.doi.org/10.1016/j.clgc.2015.12.006DOI Listing
June 2016

Impact of Obesity on Complications of Laparoscopic Simple or Radical Nephrectomy.

Curr Urol 2015 Sep 4;8(3):149-55. Epub 2015 Sep 4.

Departement of Urology, Lyon Sud University Hospital, Pierre Benite, France.

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http://dx.doi.org/10.1159/000365707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748803PMC
September 2015

Prostate hypofractionated radiation therapy with injection of hyaluronic acid: acute toxicities in a phase 2 study.

Int J Radiat Oncol Biol Phys 2015 Mar;91(4):730-6

Department of Radiation Oncology and Physics, Institut du Cancer de Montpellier, Montpellier, France.

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http://dx.doi.org/10.1016/j.ijrobp.2014.11.027DOI Listing
March 2015

Day case laparoscopic nephrectomy with vaginal extraction: initial experience.

Urology 2014 Dec 17;84(6):1525-8. Epub 2014 Oct 17.

Department of Urology, Lyon Sud University Hospital, Pierre Benite, France; Université Claude Bernard Lyon 1, Lyon, France. Electronic address:

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http://dx.doi.org/10.1016/j.urology.2014.06.084DOI Listing
December 2014

p16(INK4a) overexpression is not linked to oncogenic human papillomaviruses in patients with high-grade urothelial cancer cells.

Cancer Cytopathol 2014 Oct 28;122(10):760-9. Epub 2014 Jul 28.

Université Claude Bernard Lyon 1, Lyon, France; Centre de Pathologie Est, Hôpital Femme-Mère-Enfant, Hospices Civils de Lyon, Bron, France.

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http://dx.doi.org/10.1002/cncy.21462DOI Listing
October 2014

Comparative evaluation of urinary PCA3 and TMPRSS2: ERG scores and serum PHI in predicting prostate cancer aggressiveness.

Int J Mol Sci 2014 Jul 30;15(8):13299-316. Epub 2014 Jul 30.

Medical Unit of Molecular Oncology and Transfer, Department of Biochemistry and Molecular Biology, University Hospital of Lyon Sud, Hospices Civils of Lyon, Chemin du Grand Revoyet, 69495 Pierre Bénite, France.

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http://www.mdpi.com/1422-0067/15/8/13299
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http://dx.doi.org/10.3390/ijms150813299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159795PMC
July 2014

p16 INK4a overexpression and p16/Ki-67 dual labeling versus conventional urinary cytology in the evaluation of urothelial carcinoma.

Cancer Cytopathol 2014 Mar 2;122(3):211-20. Epub 2013 Dec 2.

Hospices Civils de Lyon, Centre de Biologie et Pathologie Est, Hôpital Femme-Mère-Enfant, Lyon Bron, France; Université Claude Bernard Lyon 1, Lyon, France.

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http://doi.wiley.com/10.1002/cncy.21376
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http://dx.doi.org/10.1002/cncy.21376DOI Listing
March 2014

Differentially expressed androgen-regulated genes in androgen-sensitive tissues reveal potential biomarkers of early prostate cancer.

PLoS One 2013 28;8(6):e66278. Epub 2013 Jun 28.

Institut de Génomique Fonctionnelle de Lyon (IGFL), Université de Lyon, CNRS UMR5242, INRA1288, Ecole Normale Supérieure de Lyon, Lyon, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0066278PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696068PMC
January 2014

Surgical outcomes and patients' satisfaction with suprapubic phalloplasty.

J Sex Med 2014 Jan 12;11(1):288-98. Epub 2013 Sep 12.

Service d'urologie, Centre hospitalier Lyon-Sud, Hospices civils de Lyon, Pierre-Bénite Cedex, France.

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http://dx.doi.org/10.1111/jsm.12297DOI Listing
January 2014

PCA3 and PCA3-based nomograms improve diagnostic accuracy in patients undergoing first prostate biopsy.

Int J Mol Sci 2013 Aug 29;14(9):17767-80. Epub 2013 Aug 29.

Department of Urology, University Hospital of Lyon Sud, Hospices Civils of Lyon, Pierre Bénite 69495, France.

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http://dx.doi.org/10.3390/ijms140917767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794752PMC
August 2013

Prostate hypofractionated radiation therapy: injection of hyaluronic acid to better preserve the rectal wall.

Int J Radiat Oncol Biol Phys 2013 May 3;86(1):72-6. Epub 2013 Jan 3.

Department of Radiation Oncology, Centre Hospitalier Lyon Sud, Pierre Benite, France.

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http://dx.doi.org/10.1016/j.ijrobp.2012.11.027DOI Listing
May 2013

Critical role of prostate biopsy mortality in the number of years of life gained and lost within a prostate cancer screening programme.

BJU Int 2012 Dec 18;110(11):1648-52. Epub 2012 Sep 18.

International Prevention Research Institute, Lyon Hospices Civils de Lyon, Pierre-Bénite, France.

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http://doi.wiley.com/10.1111/j.1464-410X.2012.11513.x
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http://dx.doi.org/10.1111/j.1464-410X.2012.11513.xDOI Listing
December 2012

[Prostate-specific antigen use among men without prostate cancer in France (2008-2010)].

Bull Cancer 2012 May;99(5):521-7

CNAMTS (Caisse nationale d'assurance maladie des travailleurs salariés), 50, avenue du Professeur-André-Lemierre, 75986 Paris Cedex 20, France.

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http://dx.doi.org/10.1684/bdc.2012.1580DOI Listing
May 2012

In vitro affinity maturation of an anti-PSA antibody for prostate cancer diagnostic assay.

J Mol Biol 2011 Dec 12;414(4):545-62. Epub 2011 Oct 12.

CEA, iBiTec-S, Service de Pharmacologie et d'Immunoanalyse, Laboratoire d'Ingénierie des Anticorps pour la Santé, Equipe mixte CEA/bioMérieux, Gif-sur-Yvette F-91191, France.

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http://dx.doi.org/10.1016/j.jmb.2011.10.008DOI Listing
December 2011

Down-regulation of DcR2 sensitizes androgen-dependent prostate cancer LNCaP cells to TRAIL-induced apoptosis.

Cancer Cell Int 2011 Dec 2;11:42. Epub 2011 Dec 2.

SF Biosciences Gerland-Lyon Sud, CNRS UMS3444/Inserm US8, Université Claude Bernard Lyon 1, 50 avenue Tony Garnier, 69366 Lyon, France.

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http://dx.doi.org/10.1186/1475-2867-11-42DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286382PMC
December 2011

TM4SF1, a novel primary androgen receptor target gene over-expressed in human prostate cancer and involved in cell migration.

Prostate 2011 Aug 12;71(11):1239-50. Epub 2011 Jan 12.

Institut de Génomique Fonctionnelle de Lyon, Université de Lyon, Lyon, France.

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http://dx.doi.org/10.1002/pros.21340DOI Listing
August 2011

[Value of PCA3 urinary test for prostate biopsy decision: the Lyon-Sud University Hospital experience].

Ann Biol Clin (Paris) 2011 Jan-Feb;69(1):31-9

Unité médicale d'oncologie et transfert, Service de biochimie et biologie moléculaire Sud, Centre hospitalier Lyon Sud, Pierre.

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http://dx.doi.org/10.1684/abc.2010.0513DOI Listing
May 2011

Urinary PCA3 score predicts prostate cancer multifocality.

J Urol 2011 Apr 22;185(4):1234-9. Epub 2011 Feb 22.

Department of Medical Unit of Molecular Oncology and Transfer, Medical Faculty of Lyon 1 University, Lyon, France.

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https://linkinghub.elsevier.com/retrieve/pii/S00225347100518
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http://dx.doi.org/10.1016/j.juro.2010.11.072DOI Listing
April 2011

Treatment of neurogenic male urinary incontinence related to intrinsic sphincter insufficiency with an artificial urinary sphincter: a French retrospective multicentre study.

BJU Int 2011 Feb;107(3):426-32

Service d'Urologie, Groupe hospitalier Pitié-Salpêtrière, Assistance Publique Hopitaux de Paris, Université Paris-VI, Paris, France.

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http://dx.doi.org/10.1111/j.1464-410X.2010.09501.xDOI Listing
February 2011

[Atypical urothelial cells (AUC): A Bethesda-derived wording applicable to urinary cytopathology].

Ann Pathol 2011 Feb 28;31(1):11-7. Epub 2011 Jan 28.

Centre de pathologie Est, hôpital femme-mère-enfant, Bron, France.

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http://dx.doi.org/10.1016/j.annpat.2010.09.010DOI Listing
February 2011

[Microsatellite markers and methylation of promoters of tumour suppressor genes in bladder cancer].

Ann Pathol 2010 Nov 15;30(5 Suppl 1):119-20. Epub 2010 Sep 15.

Service de biochimie et biologie moléculaire, CHU de Lyon-Sud, hospices civils de Lyon, Pierre-Bénite cedex, France.

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http://dx.doi.org/10.1016/j.annpat.2010.07.022DOI Listing
November 2010

Quantitative loss of heterozygosity analysis for urothelial carcinoma detection and prognosis.

Urology 2010 Aug 5;76(2):515.e1-7. Epub 2010 Mar 5.

Service de Biochimie et Biologie Moléculaire Sud, Centre Hospitalier Universitaire Lyon Sud, Chemin du Grand Revoyet, Pierre Bénite, Hospices Civils de Lyon, France.

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http://dx.doi.org/10.1016/j.urology.2009.11.046DOI Listing
August 2010

Urinary prostate cancer 3 test: toward the age of reason?

Urology 2010 Feb 8;75(2):447-53. Epub 2009 Jul 8.

Department of Molecular Oncology and Transfert, Lyon Sud Hospital, Pierre-Bénite, France.

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http://dx.doi.org/10.1016/j.urology.2009.03.046DOI Listing
February 2010

[Isolated testicular mass revealing a metastasis of prostate adenocarcinoma].

Ann Pathol 2009 Dec;29(6):488-90

Service d'anatomie pathologique, centre hospitalier Lyon-Sud, 69495 Pierre-Bénite cedex, France.

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http://dx.doi.org/10.1016/j.annpat.2009.10.022DOI Listing
December 2009

Long-term outcome of forearm flee-flap phalloplasty in the treatment of transsexualism.

BJU Int 2008 May 8;101(10):1297-300. Epub 2008 Jan 8.

Department of Urology, Henry Gabrielle Hospital, University of Lyon I, Lyon, France.

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http://doi.wiley.com/10.1111/j.1464-410X.2007.07362.x
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http://dx.doi.org/10.1111/j.1464-410X.2007.07362.xDOI Listing
May 2008

Association between sarcoidosis and testicular carcinoma: a diagnostic pitfall.

Sarcoidosis Vasc Diffuse Lung Dis 2007 Sep;24(2):95-101

Department of Urology, Memorial Sloan-Kettering Cancer center, New York City, New York, USA.

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September 2007

The neurogenic bladder in multiple sclerosis: review of the literature and proposal of management guidelines.

Mult Scler 2007 Aug 15;13(7):915-28. Epub 2007 Mar 15.

Unité d'Evaluation et de Traitement du Handicap Urinaire, Service de Médecine Physique et de Réadaptation, CHU Pellegrin, Equipe de Recherche Handicap et Système Nerveux, Bordeaux Cedex, France.

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http://journals.sagepub.com/doi/10.1177/1352458506075651
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http://dx.doi.org/10.1177/1352458506075651DOI Listing
August 2007

Surgical principles of omentoplasty in urology.

BJU Int 2007 May;99(5):1191-6

Department of Urology, Lyon Sud Hospital, Pierre Benite, France.

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http://doi.wiley.com/10.1111/j.1464-410X.2007.06869.x
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http://dx.doi.org/10.1111/j.1464-410X.2007.06869.xDOI Listing
May 2007

[Value of urinary markers in the diagnosis and follow-up of urothelial bladder tumours].

Prog Urol 2007 Feb;17(1):23-34

Service d'Urologie, Centre Hospitalier Lyon-Sud, Lyon, Pierre Bénite, France.

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February 2007

[Chemical destruction of sacral nerve roots by alcohol injection for the treatment of overactive bladder].

Prog Urol 2006 Nov;16(5):584-7

Service d'Urologie, Hôpital Henry Gabrielle, Saint Genis Laval, France.

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November 2006

What is the optimum dose of type A botulinum toxin for treating neurogenic bladder overactivity?

BJU Int 2006 May;97(5):1030-4

Hôpital Henry Gabrielle, Saint Genis Laval, and Hôpital Charles Nicolle, Rouens, France.

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http://doi.wiley.com/10.1111/j.1464-410X.2006.06091.x
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http://dx.doi.org/10.1111/j.1464-410X.2006.06091.xDOI Listing
May 2006

[A modified IPSS score: value of a choice of qualitative answers].

Prog Urol 2006 Apr;16(2):168-73

Service d'Urologie, Centre Hospitalier Lyon-Sud, Pierre Bénite, France.

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April 2006

[REMEEX: A possible treatment option in selected cases of sphincter incompetence].

Prog Urol 2006 Apr;16(2):184-91

Service d'Urologie, Centre Hospitalier Lyon Sud, Lyon, France.

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April 2006

[Management of corpus cavernosum trauma].

Prog Urol 2006 Feb;16(1):12-8

Service de Chirurgie Urologique et de la transplantation rénale, Centre Hospitalier Lyon Sud, Pierre Bénite, France.

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February 2006