Akram Pourshams

Akram Pourshams

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Akram Pourshams

Publications by authors named "Akram Pourshams"

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Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.

Lancet 2019 08;394(10199):672-683

Digestive Disease Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran; Digestive Oncology Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran; Liver and Pancreaticobiliary Disease Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(19)31791-XDOI Listing
August 2019

Gastrointestinal symptoms in patients with diabetes mellitus and non-diabetic: A cross-sectional study in north of Iran.

Diabetes Metab Syndr 2019 May - Jun;13(3):2236-2240. Epub 2019 May 25.

GI Cancer Screening and Prevention Research Center, Guilan University of Medical Sciences, Rasht, Iran; Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.dsx.2019.05.028DOI Listing
May 2019

Individual and Combined Effects of Environmental Risk Factors for Esophageal Cancer Based on Results From the Golestan Cohort Study.

Gastroenterology 2019 Apr 3;156(5):1416-1427. Epub 2019 Jan 3.

Digestive Oncology Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Digestive Disease Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085183543
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http://dx.doi.org/10.1053/j.gastro.2018.12.024DOI Listing
April 2019

An Increased Level of Aryl Hydrocarbon Receptor in Patients with Pancreatic Cancer.

Middle East J Dig Dis 2019 Jan 4;11(1):38-44. Epub 2018 Oct 4.

Liver and Pancreatobiliary Diseases Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

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http://mejdd.org/index.php/mejdd/article/view/1945
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http://dx.doi.org/10.15171/mejdd.2018.126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488497PMC
January 2019

Mutations in Known and Novel cancer Susceptibility Genes in Young Patients with Pancreatic Cancer.

Arch Iran Med 2018 06 1;21(6):228-233. Epub 2018 Jun 1.

Liver and Pancreatobiliary Diseases Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

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June 2018

Drug Use for Secondary Prevention of Cardiovascular Diseases in Golestan, Iran: Results From the Golestan Cohort Study.

Arch Iran Med 2018 03 1;21(3):86-94. Epub 2018 Mar 1.

Digestive Disease Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

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March 2018

Menstrual and Reproductive Factors and Risk of Pancreatic Cancer in Women.

Middle East J Dig Dis 2017 Jul;9(3):146-149

Digestive Oncology Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

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http://mejdd.org/index.php/mejdd/article/view/1828
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http://dx.doi.org/10.15171/mejdd.2017.65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585906PMC
July 2017

Pancreatic Cancer is Associated with Peripheral Leukocyte Oxidative DNA Damage

Asian Pac J Cancer Prev 2017 05 1;18(5):1349-1355. Epub 2017 May 1.

Liver and Pancreatobiliary Diseases Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. Email:

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http://dx.doi.org/10.22034/APJCP.2017.18.5.1349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555546PMC
May 2017

Dietary Protein Sources and All-Cause and Cause-Specific Mortality: The Golestan Cohort Study in Iran.

Am J Prev Med 2017 Feb;52(2):237-248

Digestive Disease Research Center, Digestive Disease, Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Digestive Oncology Research Center, Digestive Disease, Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Liver and Pancreatobiliary Diseases Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.amepre.2016.10.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360102PMC
February 2017

Opium use, cigarette smoking, and alcohol consumption in relation to pancreatic cancer.

Medicine (Baltimore) 2016 Jul;95(28):e3922

aDigestive Oncology Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran bDigestive Disease Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran cDepartment of Public Health Analysis, School of Community Health and Policy, Morgan State University, Baltimore, MD dLiver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences eGastrointestinal and Liver Disease Research Center, Firoozgar Hospital, Iran University of Medical Sciences fSasan Alborz Biomedical Research Center, Masoud Gastroenterology and Hepatology Clinic, Tehran, Iran gDivision of Gastroenterology and Hepatology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins Medical Institutions, Baltimore, MD hAmerican Cancer Society, Atlanta, GA iInstitute for Transitional Epidemiology and the Tisch Cancer Institute, Mount Sinai School of Medicine, New York, NY.

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http://dx.doi.org/10.1097/MD.0000000000003922DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956779PMC
July 2016

Household Fuel Use and Cardiovascular Disease Mortality: Golestan Cohort Study.

Circulation 2016 Jun;133(24):2360-9

From Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (S.S.M.); Zena and Michael A. Wiener Cardiovascular Institute (R.V., V.F.) and Tisch Cancer Institute and Institute for Translational Epidemiology (F.I., P.B.), Icahn School of Medicine at Mount Sinai, New York, NY; Digestive Oncology Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran (F.I., A.P., R.M.); Surveillance and Health Services Research, American Cancer Society, Atlanta, GA (F.I.); International Agency for Research on Cancer, Lyon, France (H.K., P.B.); Department of Public Health Analysis, School of Community Health and Policy, Morgan State University, Baltimore, MD (F.K.); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD (C.C.A.); Departments of Oncology and Public Health and Primary Care, University of Cambridge, UK (P.D.P.); Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain (V.F.); and International Prevention Research Institute, Lyon, France (P.B.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.020288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910632PMC
June 2016

Major Dietary Protein Sources in Relation to Pancreatic Cancer: a Large Prospective Study.

Arch Iran Med 2016 Apr;19(4):248-56

Departments of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/0161904/AIM.005DOI Listing
April 2016

Solid Pseudopapillary Neoplasm of Pancreas; A Case Series and Review Literature.

Middle East J Dig Dis 2016 Apr;8(2):102-8

Digestive Oncology Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.15171/mejdd.2016.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885608PMC
April 2016

Inverse Association of Plasma Level of Glutathione Peroxidase with Liver Fibrosis in Chronic Hepatitis B: Potential Role of Iron.

Middle East J Dig Dis 2016 Apr;8(2):122-30

Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.15171/mejdd.2016.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885611PMC
April 2016

Food preparation methods, drinking water source, and esophageal squamous cell carcinoma in the high-risk area of Golestan, Northeast Iran.

Eur J Cancer Prev 2016 Mar;25(2):123-9

aDigestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran bGolestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran cDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda dDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health eSchool of Community Health and Policy, Morgan State University, Baltimore, Maryland fThe Tisch Cancer Institute and Institute for Translational Epidemiology, Mount Sinai School of Medicine, New York, New York, USA gMedical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden hGenetic Epidemiology Group, International Agency for Research on Cancer, Lyon, France.

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http://dx.doi.org/10.1097/CEJ.0000000000000156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759050PMC
March 2016

Multimorbidity: Epidemiology and Risk Factors in the Golestan Cohort Study, Iran: A Cross-Sectional Analysis.

Medicine (Baltimore) 2016 Feb;95(7):e2756

From the Department of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences (BA), Tehran, Iran; Digestive Disease Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences (MA, AM, MB, FI, HP, AFS, AP, FK, AS, RM), Tehran, Iran; Digestive Oncology Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences (MA, MB, HP, MHD, AFS, AP, AS, RM), Tehran, Iran; Department of Human Ecology, School of Public Health, Tehran University of Medical Sciences (MA), Tehran, Iran; Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences (MY), Tehran, Iran; Surveillance and Health Services Research, American Cancer Society (FI), Atlanta, GA; Institute for Translational Epidemiology and Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai (PB), New York, NY; Division of Cardiovascular and Medical Sciences, Section of Gastroenterology, University of Glasgow (MHD), Glasgow, UK; Liver and Pancreatic-biliary Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences (AP), Tehran, Iran; Division of Cancer Epidemiology and Genetics, National Cancer Institute (CCA, SMD), Bethesda, MD; International Agency for Research on Cancer, Genetic Epidemiology Group (PB), Lyon, France; and Department of Public Health Analysis, School of Community Health and Policy, Morgan State University (FK), Baltimore, MD.

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http://dx.doi.org/10.1097/MD.0000000000002756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998618PMC
February 2016

The clinical performance of an office-based risk scoring system for fatal cardiovascular diseases in North-East of Iran.

PLoS One 2015 26;10(5):e0126779. Epub 2015 May 26.

Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran; Department of Public Health Analysis, School of Community Health and Policy, Morgan State University, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126779PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444120PMC
January 2016

The Nail as a Biomonitor of Trace Element Status in Golestan Cohort Study.

Middle East J Dig Dis 2016 Jan;8(1):19-23

Digestive Oncology Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.15171/mejdd.2016.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773078PMC
January 2016

Burden of Gastrointestinal and Liver Diseases in Middle East and North Africa: Results of Global Burden of Diseases Study from 1990 to 2010.

Middle East J Dig Dis 2015 Oct;7(4):201-15

Digestive Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran ; Liver and Pancreatobilliary Diseases Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran ; Digestive Oncology Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655840PMC
October 2015

Cooking methods and esophageal squamous cell carcinoma in high-risk areas of Iran.

Nutr Cancer 2014 13;66(3):500-5. Epub 2013 Sep 13.

a Digestive Disease Research Center, Shariati Hospital, Tehran University of Medical Sciences , Tehran , Iran.

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http://dx.doi.org/10.1080/01635581.2013.779384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749919PMC
May 2015

Dietary food groups intake and cooking methods associations with pancreatic cancer: a case-control study.

Indian J Gastroenterol 2015 May 12;34(3):225-32. Epub 2015 Jun 12.

Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology, Research Institute Shahid Beheshti University of Medical Science, Tehran, Iran.

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http://dx.doi.org/10.1007/s12664-015-0573-4DOI Listing
May 2015

Network of microRNAs-mRNAs interactions in pancreatic cancer.

Biomed Res Int 2014 7;2014:534821. Epub 2014 May 7.

Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1155/2014/534821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033392PMC
January 2015

Cohort profile: golestan hepatitis B cohort study- a prospective long term study in northern iran ​.

Middle East J Dig Dis 2014 Oct;6(4):186-94

Liver and Pancreatobiliary Diseases Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran university of Medical Sciences, Tehran, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208926PMC
October 2014

Clinical and pathological features of non-functional neuroendocrine tumors of pancreas: a report from iran.

Middle East J Dig Dis 2014 Jul;6(3):151-5

Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119672PMC
July 2014

Detection of TP53 R249 Mutation in Iranian Patients with Pancreatic Cancer.

J Oncol 2013 30;2013:738915. Epub 2013 Dec 30.

Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1155/2013/738915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892507PMC
February 2014

Validity and reliability of a questionnaire designed to assess risk factors of pancreatic cancer in Iran.

Arch Iran Med 2014 Feb;17(2):102-5

Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/014172/AIM.003DOI Listing
February 2014

Normal limit for serum alanine aminotransferase level and distribution of metabolic factors in old population of kalaleh, iran.

Hepat Mon 2013 20;13(10):e10640. Epub 2013 Oct 20.

Digestive Disease Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, IR Iran.

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http://dx.doi.org/10.5812/hepatmon.10640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842514PMC
December 2013

Opium use and risk of mortality from digestive diseases: a prospective cohort study.

Am J Gastroenterol 2013 Nov 22;108(11):1757-65. Epub 2013 Oct 22.

1] Digestive Disease Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran [2] These authors contributed equally to this work.

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http://dx.doi.org/10.1038/ajg.2013.336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752100PMC
November 2013

Endoscopic screening for esophageal squamous cell carcinoma.

Arch Iran Med 2013 Jun;16(6):351-7

Digestive Diseases Research Institute DDRI, Tehran University of Medical Sciences TUMS, Tehran, Iran.

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http://dx.doi.org/013166/AIM.009DOI Listing
June 2013

Squamous cell carcinoma of the pancreas.

Arch Iran Med 2013 Jun;16(6):369-70

Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/013166/AIM.0012DOI Listing
June 2013

Obtaining informed consent in an illiterate population.

Middle East J Dig Dis 2013 Jan;5(1):37-40

Digestive Disease Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990137PMC
January 2013

Mutations in Fanconi anemia genes and the risk of esophageal cancer.

Hum Genet 2011 May 30;129(5):573-82. Epub 2011 Jan 30.

Digestive Disease Research Center, Shariati Hospital, Tehran University of Medical Sciences, North Kargar Street, Tehran, Iran.

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http://dx.doi.org/10.1007/s00439-011-0951-7DOI Listing
May 2011

Seroprevalence of hepatitis C virus: the first population-based study from Iran.

Int J Infect Dis 2010 Sep 2;14 Suppl 3:e113-6. Epub 2010 Apr 2.

Digestive Disease Research Center, Shariati Hospital, Tehran University of Medical Sciences, N Kargar Street, Tehran, Iran.

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http://dx.doi.org/10.1016/j.ijid.2009.11.032DOI Listing
September 2010

Vitamin deficiency in Golestan Province, northern Iran: a high-risk area for esophageal cancer.

Arch Iran Med 2010 Sep;13(5):391-4

Digestive Disease Research Center, Shariati Hospital, University of Tehran Medical Sciences, Kargar-e-shomali Ave., Tehran, Iran.

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http://dx.doi.org/010135/AIM.005DOI Listing
September 2010

Role of cytochrome P450 2C19 genetic polymorphisms in the therapeutic efficacy of omeprazole in Iranian patients with erosive reflux esophagitis.

Arch Iran Med 2010 Sep;13(5):406-12

National Institute of Genetic Engineering and Biotechnology, Pajoohesh Boulevard, Km 17, Tehran-Karaj Highway,Tehran, Iran.

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http://dx.doi.org/010135/AIM.007DOI Listing
September 2010

Pictogram use was validated for estimating individual's body mass index.

J Clin Epidemiol 2010 Jun 12;63(6):655-9. Epub 2009 Nov 12.

Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran.

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http://dx.doi.org/10.1016/j.jclinepi.2009.08.014DOI Listing
June 2010

Seroprevalence and risk factors of hepatitis A virus infection in Iran: a population based study.

Arch Iran Med 2010 Mar;13(2):99-104

Digestive Disease Research Center, Shariati Hospital, Tehran University of Medical Sciences, N. Kargar Street, Tehran, Iran.

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March 2010

The upper normal limit of serum alanine aminotransferase in Golestan Province, northeast Iran.

Arch Iran Med 2008 Nov;11(6):602-7

Tehran University of Medical Sciences, Shariati Hospital, Tehran, Iran.

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November 2008

Tooth loss and lack of regular oral hygiene are associated with higher risk of esophageal squamous cell carcinoma.

Cancer Epidemiol Biomarkers Prev 2008 Nov;17(11):3062-8

Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Executive Plaza South, Room 320, 6120 Executive Boulevard, MSC 7232, Rockville, MD 20852, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-08-0558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586052PMC
November 2008

Dietary intake of benzo(a)pyrene and risk of esophageal cancer in north of Iran.

Nutr Cancer 2008 ;60(2):216-21

Digestive Disease Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1080/01635580701684831DOI Listing
July 2008

The normal range of duodenal intraepithelial lymphocytes.

Arch Iran Med 2008 Mar;11(2):136-42

Digestive Disease Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/08112/AIM.003DOI Listing
March 2008

Modified jejunoileal bypass surgery with biliary diversion for morbid obesity and changes in liver histology during follow-up.

J Gastrointest Surg 2007 Aug;11(8):1033-8

Department of Surgery, Medical School, Shahid Beheshti University of Medical Sciences, P.O. Box 19395/4655, Tehran, Iran.

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http://dx.doi.org/10.1007/s11605-007-0184-1DOI Listing
August 2007

The preventive polypill--much promise, insufficient evidence.

Arch Iran Med 2007 Jul;10(3):430-1

Digestive Disease Research Center, Medical Sciences/Tehran University, Tehran, Iran.

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http://dx.doi.org/07103/AIM.0032DOI Listing
July 2007

High exposure to polycyclic aromatic hydrocarbons may contribute to high risk of esophageal cancer in northeastern Iran.

Anticancer Res 2005 Jan-Feb;25(1B):425-8

Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 21218, USA.

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May 2005

Prevalence and etiology of persistently elevated alanine aminotransferase levels in healthy Iranian blood donors.

J Gastroenterol Hepatol 2005 Feb;20(2):229-33

Digestive Disease Research Center, Tehran University of Medical Sciences, Shariati Hospital, North Kargar Avenue, Tehran, Iran.

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http://dx.doi.org/10.1111/j.1440-1746.2004.03511.xDOI Listing
February 2005

Reliability and validity of opiate use self-report in a population at high risk for esophageal cancer in Golestan, Iran.

Cancer Epidemiol Biomarkers Prev 2004 Jun;13(6):1068-70

Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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June 2004