Publications by authors named "Akira Sawa"

99Publications

Endoscopy and Barrett's Esophagus: Current Perspectives in the US and Japan.

Intern Med 2020 Aug 29. Epub 2020 Aug 29.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, USA.

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http://dx.doi.org/10.2169/internalmedicine.4400-19DOI Listing
August 2020

Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders.

Authors:
Yash Patel Nadine Parker Jean Shin Derek Howard Leon French Sophia I Thomopoulos Elena Pozzi Yoshinari Abe Christoph Abé Alan Anticevic Martin Alda Andre Aleman Clara Alloza Silvia Alonso-Lana Stephanie H Ameis Evdokia Anagnostou Andrew A McIntosh Celso Arango Paul D Arnold Philip Asherson Francesca Assogna Guillaume Auzias Rosa Ayesa-Arriola Geor Bakker Nerisa Banaj Tobias Banaschewski Cibele E Bandeira Alexandr Baranov Núria Bargalló Claiton H D Bau Sarah Baumeister Bernhard T Baune Mark A Bellgrove Francesco Benedetti Alessandro Bertolino Premika S W Boedhoe Marco Boks Irene Bollettini Caterina Del Mar Bonnin Tiana Borgers Stefan Borgwardt Daniel Brandeis Brian P Brennan Jason M Bruggemann Robin Bülow Geraldo F Busatto Sara Calderoni Vince D Calhoun Rosa Calvo Erick J Canales-Rodríguez Dara M Cannon Vaughan J Carr Nicola Cascella Mara Cercignani Tiffany M Chaim-Avancini Anastasia Christakou David Coghill Annette Conzelmann Benedicto Crespo-Facorro Ana I Cubillo Kathryn R Cullen Renata B Cupertino Eileen Daly Udo Dannlowski Christopher G Davey Damiaan Denys Christine Deruelle Annabella Di Giorgio Erin W Dickie Danai Dima Katharina Dohm Stefan Ehrlich Benjamin A Ely Tracy Erwin-Grabner Thomas Ethofer Damien A Fair Andreas J Fallgatter Stephen V Faraone Mar Fatjó-Vilas Jennifer M Fedor Kate D Fitzgerald Judith M Ford Thomas Frodl Cynthia H Y Fu Janice M Fullerton Matt C Gabel David C Glahn Gloria Roberts Tinatin Gogberashvili Jose M Goikolea Ian H Gotlib Roberto Goya-Maldonado Hans J Grabe Melissa J Green Eugenio H Grevet Nynke A Groenewold Dominik Grotegerd Oliver Gruber Patricia Gruner Amalia Guerrero-Pedraza Raquel E Gur Ruben C Gur Shlomi Haar Bartholomeus C M Haarman Jan Haavik Tim Hahn Tomas Hajek Benjamin J Harrison Neil A Harrison Catharina A Hartman Heather C Whalley Dirk J Heslenfeld Derrek P Hibar Eva Hilland Yoshiyuki Hirano Tiffany C Ho Pieter J Hoekstra Liesbeth Hoekstra Sarah Hohmann L E Hong Cyril Höschl Marie F Høvik Fleur M Howells Igor Nenadic Maria Jalbrzikowski Anthony C James Joost Janssen Fern Jaspers-Fayer Jian Xu Rune Jonassen Georgii Karkashadze Joseph A King Tilo Kircher Matthias Kirschner Kathrin Koch Peter Kochunov Gregor Kohls Kerstin Konrad Bernd Krämer Axel Krug Jonna Kuntsi Jun Soo Kwon Mikael Landén Nils I Landrø Luisa Lazaro Irina S Lebedeva Elisabeth J Leehr Sara Lera-Miguel Klaus-Peter Lesch Christine Lochner Mario R Louza Beatriz Luna Astri J Lundervold Frank P MacMaster Luigi A Maglanoc Charles B Malpas Maria J Portella Rachel Marsh Fiona M Martyn David Mataix-Cols Daniel H Mathalon Hazel McCarthy Colm McDonald Genevieve McPhilemey Susanne Meinert José M Menchón Luciano Minuzzi Philip B Mitchell Carmen Moreno Pedro Morgado Filippo Muratori Clodagh M Murphy Declan Murphy Benson Mwangi Leila Nabulsi Akiko Nakagawa Takashi Nakamae Leyla Namazova Janardhanan Narayanaswamy Neda Jahanshad Danai D Nguyen Rosa Nicolau Ruth L O'Gorman Tuura Kirsten O'Hearn Jaap Oosterlaan Nils Opel Roel A Ophoff Bob Oranje Victor Ortiz García de la Foz Bronwyn J Overs Yannis Paloyelis Christos Pantelis Mara Parellada Paul Pauli Maria Picó-Pérez Felipe A Picon Fabrizio Piras Federica Piras Kerstin J Plessen Edith Pomarol-Clotet Adrian Preda Olga Puig Yann Quidé Joaquim Radua J Antoni Ramos-Quiroga Paul E Rasser Lisa Rauer Janardhan Reddy Ronny Redlich Andreas Reif Liesbeth Reneman Jonathan Repple Alessandra Retico Vanesa Richarte Anja Richter Pedro G P Rosa Katya K Rubia Ryota Hashimoto Matthew D Sacchet Raymond Salvador Javier Santonja Kelvin Sarink Salvador Sarró Theodore D Satterthwaite Akira Sawa Ulrich Schall Peter R Schofield Anouk Schrantee Jochen Seitz Mauricio H Serpa Esther Setién-Suero Philip Shaw Devon Shook Tim J Silk Kang Sim Schmitt Simon Helen Blair Simpson Aditya Singh Antonin Skoch Norbert Skokauskas Jair C Soares Noam Soreni Carles Soriano-Mas Gianfranco Spalletta Filip Spaniel Stephen M Lawrie Emily R Stern S Evelyn Stewart Yoichiro Takayanagi Henk S Temmingh David F Tolin David Tomecek Diana Tordesillas-Gutiérrez Michela Tosetti Anne Uhlmann Therese van Amelsvoort Nic J A van der Wee Steven J A van der Werff Neeltje E M van Haren Guido A van Wingen Alasdair Vance Javier Vázquez-Bourgon Daniela Vecchio Ganesan Venkatasubramanian Eduard Vieta Oscar Vilarroya Yolanda Vives-Gilabert Aristotle N Voineskos Henry Völzke Georg G von Polier Esther Walton Thomas W Weickert Cynthia Shannon Weickert Andrea S Weideman Katharina Wittfeld Daniel H Wolf Mon-Ju Wu T T Yang Kun Yang Yuliya Yoncheva Je-Yeon Yun Yuqi Cheng Marcus V Zanetti Georg C Ziegler Barbara Franke Martine Hoogman Jan K Buitelaar Daan van Rooij Ole A Andreassen Christopher R K Ching Dick J Veltman Lianne Schmaal Dan J Stein Odile A van den Heuvel Jessica A Turner Theo G M van Erp Zdenka Pausova Paul M Thompson Tomáš Paus

JAMA Psychiatry 2020 Aug 26. Epub 2020 Aug 26.

Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1001/jamapsychiatry.2020.2694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450410PMC
August 2020

Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA.

Neuroimage 2020 09 26;218:116956. Epub 2020 May 26.

Clinical Translational Neuroscience Laboratory, Department of Psychiatry and Human Behavior, University of California Irvine, Irvine, CA, USA; Center for the Neurobiology of Learning and Memory, University of California Irvine, 309 Qureshey Research Lab, Irvine, CA, 92697, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2020.116956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524039PMC
September 2020

Neurometabolic underpinning of the intergenerational transmission of prosociality.

Neuroimage 2020 09 24;218:116965. Epub 2020 May 24.

Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; International Research Center for Neurointelligence (WPI-IRCN), The University of Tokyo Institutes for Advanced Study (UTIAS), The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.neuroimage.2020.116965DOI Listing
September 2020

Neurodevelopmental Factors in Schizophrenia.

Psychiatr Clin North Am 2020 06 22;43(2):263-274. Epub 2020 Apr 22.

Department of Psychiatry, Johns Hopkins University School of Medicine, Johns Hopkins University Bloomberg School of Public Health, Johns Hopkins Hospital, Meyer 3-166, 600 North Wolfe Street, Baltimore, MD, 21287, USA; Department of Neuroscience, Johns Hopkins University School of Medicine, Johns Hopkins University Bloomberg School of Public Health, Johns Hopkins Hospital, Meyer 3-166, 600 North Wolfe Street, Baltimore, MD 21287, USA; Department of Mental Health, Johns Hopkins University School of Medicine, Johns Hopkins University Bloomberg School of Public Health, Johns Hopkins Hospital, Meyer 3-166, 600 North Wolfe Street, Baltimore, MD 21287, USA; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Johns Hopkins University Bloomberg School of Public Health, Johns Hopkins Hospital, Meyer 3-166, 600 North Wolfe Street, Baltimore, MD 21287, USA; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Johns Hopkins University Bloomberg School of Public Health, Johns Hopkins Hospital, Meyer 3-166, 600 North Wolfe Street, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.psc.2020.02.010DOI Listing
June 2020

Effect of multi-session prefrontal transcranial direct current stimulation on cognition in schizophrenia: A systematic review and meta-analysis.

Schizophr Res 2020 02 9;216:367-373. Epub 2019 Dec 9.

Department of Preventive Intervention for Psychiatric Disorders, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2019.11.011DOI Listing
February 2020

Reply to Brune M and Theiss C: Remaining questions in the relationship between T. gondii infection and major mental illness.

Mol Psychiatry 2020 01 22;25(1):4-5. Epub 2019 Oct 22.

Departments of Psychiatry, Neuroscience, Biomedical Engineering, and Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, 21287, USA.

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http://dx.doi.org/10.1038/s41380-019-0556-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908752PMC
January 2020

Neuronal Autophagy in Synaptic Functions and Psychiatric Disorders.

Biol Psychiatry 2020 May 29;87(9):787-796. Epub 2019 Jul 29.

Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2019.07.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986983PMC
May 2020

Editorial for "What can clinical findings tell us about the neurobiology of schizophrenia? Revisited".

Neurobiol Dis 2019 11 9;131:104521. Epub 2019 Jul 9.

Departments of Psychiatry, Neuroscience, Biomedical Engineering, Mental Health, Genetic Medicine, Johns Hopkins University School of Medicine and Bloomberg School of Public Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.nbd.2019.104521DOI Listing
November 2019

The transcriptome landscape associated with Disrupted-in-Schizophrenia-1 locus impairment in early development and adulthood.

Schizophr Res 2019 08 13;210:149-156. Epub 2019 Jun 13.

Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2019.05.032DOI Listing
August 2019

An in-silico approach for discovery of microRNA-TF regulation of DISC1 interactome mediating neuronal migration.

NPJ Syst Biol Appl 2019 7;5:17. Epub 2019 May 7.

4Departments of Psychiatry, Mental Health, Neuroscience, and Biomedical Engineering, School of Medicine, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21287 USA.

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http://dx.doi.org/10.1038/s41540-019-0094-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504871PMC
April 2020

Increased Protein Insolubility in Brains From a Subset of Patients With Schizophrenia.

Am J Psychiatry 2019 09 6;176(9):730-743. Epub 2019 May 6.

The Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore (L.G. Nucifora, Lee, Peters, Yang, Margolis, Pevsner, Ross, Sawa, F.C. Nucifora); the Departments of Psychiatry and Neurology, University of Pittsburgh, and the VISN 4 Mental Illness Research, Education, and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh (MacDonald, Sweet); the Department of Neurology, Kennedy Krieger Institute, Baltimore (Norris, Pevsner); the Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore (Norris, Pevsner, Ross, Sawa); Protein Characterization Laboratory, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Frederick, Md. (Orsburn); the Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas (Gleason, Tamminga); the Department of Neurology, Johns Hopkins University School of Medicine, Baltimore (Margolis, Ross, Sawa, F.C. Nucifora); Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, Baltimore (Lee, Sawa); the Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore (Ross).

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http://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2019.18
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http://dx.doi.org/10.1176/appi.ajp.2019.18070864DOI Listing
September 2019

Relationship between neuropsychological behavior and brain white matter in first-episode psychosis.

Schizophr Res 2019 06 13;208:49-54. Epub 2019 Apr 13.

Department Psychiatry, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD, USA; Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Mental Health, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.schres.2019.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544495PMC
June 2019

A methodology for discovering novel brain-relevant peptides: Combination of ribosome profiling and peptidomics.

Neurosci Res 2020 Feb 9;151:31-37. Epub 2019 Mar 9.

Departments of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neures.2019.02.006DOI Listing
February 2020

Causal Inference on Pathophysiological Mediators in Psychiatry.

Cold Spring Harb Symp Quant Biol 2018 8;83:17-23. Epub 2019 Mar 8.

Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1101/sqb.2018.83.037655DOI Listing
March 2019

Glutathione -transferases promote proinflammatory astrocyte-microglia communication during brain inflammation.

Sci Signal 2019 02 19;12(569). Epub 2019 Feb 19.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1126/scisignal.aar2124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637164PMC
February 2019

The glutathione cycle shapes synaptic glutamate activity.

Proc Natl Acad Sci U S A 2019 02 28;116(7):2701-2706. Epub 2019 Jan 28.

Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21205.

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http://dx.doi.org/10.1073/pnas.1817885116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377501PMC
February 2019

DISC1 and Its Protein Interactomes for Mental Function.

Authors:
Akira Sawa

Biol Psychiatry 2019 02;85(4):283-284

Departments of Psychiatry, Neuroscience, Mental Health, and Biomedical Engineering, Johns Hopkins University School of Medicine and Bloomberg School of Public Health, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2018.12.011DOI Listing
February 2019

Treatment resistant schizophrenia: Clinical, biological, and therapeutic perspectives.

Neurobiol Dis 2019 11 29;131:104257. Epub 2018 Aug 29.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins Hospital, 600 N. Wolfe St., Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.nbd.2018.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395548PMC
November 2019

A mouse model of 22q11.2 deletions: Molecular and behavioral signatures of Parkinson's disease and schizophrenia.

Sci Adv 2018 08 15;4(8):eaar6637. Epub 2018 Aug 15.

Department of Research and Drug Discovery, Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1126/sciadv.aar6637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093626PMC
August 2018

Dominant-Negative DISC1 Alters the Dopaminergic Modulation of Inhibitory Interneurons in the Mouse Prefrontal Cortex.

Mol Neuropsychiatry 2018 Jun 7;4(1):20-29. Epub 2018 May 7.

Program in Neuroscience, University of Maryland Medical School, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1159/000488030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032035PMC
June 2018

Methylphenidate and Guanfacine Ameliorate ADHD-Like Phenotypes in -Deficient Mice.

Mol Neuropsychiatry 2018 May 26;3(4):223-233. Epub 2018 Apr 26.

Department of Research and Drug Discovery, Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1159/000488081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981631PMC
May 2018

Sulforaphane Augments Glutathione and Influences Brain Metabolites in Human Subjects: A Clinical Pilot Study.

Mol Neuropsychiatry 2018 May 17;3(4):214-222. Epub 2018 Apr 17.

Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1159/000487639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981770PMC
May 2018

Developmental trajectories of brain maturation and behavior: Relevance to major mental illnesses.

J Pharmacol Sci 2018 May 3;137(1):1-4. Epub 2018 May 3.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jphs.2018.04.008DOI Listing
May 2018

Dynamic Changes of the Mitochondria in Psychiatric Illnesses: New Mechanistic Insights From Human Neuronal Models.

Biol Psychiatry 2018 05 17;83(9):751-760. Epub 2018 Jan 17.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2018.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469392PMC
May 2018

Approaches to neuromodulation for schizophrenia.

J Neurol Neurosurg Psychiatry 2018 07 14;89(7):777-787. Epub 2017 Dec 14.

Department of Neurosurgery, University of Colorado at Denver Anschutz Medical Campus, Aurora, Colorado, USA.

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http://dx.doi.org/10.1136/jnnp-2017-316946DOI Listing
July 2018

DISC1 Modulates Neuronal Stress Responses by Gate-Keeping ER-Mitochondria Ca Transfer through the MAM.

Cell Rep 2017 Dec;21(10):2748-2759

Department of Life Sciences, Pohang University of Science and Technology, 790-784 Pohang, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.11.043DOI Listing
December 2017

Psychosis Beyond the 22q11.2 Deletion: Do Additional Genetic Factors Play a Role?

Am J Psychiatry 2017 11;174(11):1027-1029

From the Department of Psychiatry and Behavioral Sciences, Johns Hopkins University Hospital, Baltimore.

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http://dx.doi.org/10.1176/appi.ajp.2017.17080910DOI Listing
November 2017

Genetic interaction of DISC1 and Neurexin in the development of fruit fly glutamatergic synapses.

NPJ Schizophr 2017 Oct 27;3(1):39. Epub 2017 Oct 27.

Life and Environmental Sciences, University of Tsukuba, Tsukuba, 305-8572, Japan.

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http://dx.doi.org/10.1038/s41537-017-0040-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660244PMC
October 2017

Olfactory Functioning in First-Episode Psychosis.

Schizophr Bull 2018 04;44(3):672-680

Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1093/schbul/sbx107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890458PMC
April 2018

Open Sesame: Open Chromatin Regions Shed Light onto Non-coding Risk Variants.

Authors:
Kun Yang Akira Sawa

Cell Stem Cell 2017 09;21(3):285-287

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.08.006DOI Listing
September 2017

Case of Secondary Tics Associated With Olanzapine in an Adult.

Front Psychiatry 2017 15;8:150. Epub 2017 Aug 15.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States.

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http://dx.doi.org/10.3389/fpsyt.2017.00150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559475PMC
August 2017

Clozapine as a Model for Antipsychotic Development.

Neurotherapeutics 2017 Jul;14(3):750-761

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1007/s13311-017-0552-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509641PMC
July 2017

Disrupted-in-Schizophrenia-1 (DISC1) protein disturbs neural function in multiple disease-risk pathways.

Hum Mol Genet 2017 07;26(14):2634-2648

Tsinghua-Peking Center for Life Sciences, IDG/McGovern Institute for Brain Research, MOE Key Laboratory of Protein Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, P.R. China.

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http://dx.doi.org/10.1093/hmg/ddx147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886174PMC
July 2017

BDNF overexpression prevents cognitive deficit elicited by adolescent cannabis exposure and host susceptibility interaction.

Hum Mol Genet 2017 07;26(13):2462-2471

Laboratory of Neuroscience, Felsenstein Medical Research Center, Rabin Medical Center, Beilinson Campus, Sackler Faculty of Medicine, Tel Aviv University, 49100 Petach Tikva, Israel.

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddx139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251614PMC
July 2017

Risk of Hospitalization Due to Medication Nonadherence Identified Through EMRs of Patients With Psychosis.

Psychiatr Serv 2017 Aug 3;68(8):847-850. Epub 2017 Apr 3.

Except for Dr. Vaidya, the authors are with the Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore. Dr. Vaidya is with the Department of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore. Send correspondence to Dr. Frederick Nucifora, Jr. (e-mail: ).

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http://dx.doi.org/10.1176/appi.ps.201600334DOI Listing
August 2017

Application of olfactory tissue and its neural progenitors to schizophrenia and psychiatric research.

Curr Opin Psychiatry 2017 May;30(3):176-183

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1097/YCO.0000000000000327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471112PMC
May 2017

The Insula: An Underestimated Brain Area in Clinical Neuroscience, Psychiatry, and Neurology.

Trends Neurosci 2017 04 15;40(4):200-207. Epub 2017 Mar 15.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tins.2017.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538352PMC
April 2017

The Olfactory Neural Epithelium As a Tool in Neuroscience.

Trends Mol Med 2017 02 18;23(2):100-103. Epub 2017 Jan 18.

Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

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http://www.cell.com/trends/molecular-medicine/pdf/S1471-4914
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http://dx.doi.org/10.1016/j.molmed.2016.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399677PMC
February 2017

Analysis of differential gene expression mediated by clozapine in human postmortem brains.

Schizophr Res 2017 07 27;185:58-66. Epub 2016 Dec 27.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N. Wolfe St., Baltimore, MD 21287, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09209964163059
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http://dx.doi.org/10.1016/j.schres.2016.12.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541388PMC
July 2017

Ulk1 protects against ethanol-induced neuronal stress and cognition-related behavioral deficits.

Neurosci Res 2017 Apr 23;117:54-61. Epub 2016 Dec 23.

Kyoto University Graduate School of Medicine, Medical Innovation Center, Kyoto, Japan; University of Toronto, Centre for Addiction and Mental Health, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neures.2016.12.004DOI Listing
April 2017

Reduced superoxide dismutase-1 (SOD1) in cerebrospinal fluid of patients with early psychosis in association with clinical features.

Schizophr Res 2017 05 23;183:64-69. Epub 2016 Nov 23.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, United States. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2016.10.040DOI Listing
May 2017

Valley of death: A proposal to build a "translational bridge" for the next generation.

Neurosci Res 2017 Feb 19;115:1-4. Epub 2016 Nov 19.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States. Electronic address:

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http://dx.doi.org/10.1016/j.neures.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477974PMC
February 2017

A Mutation in NPAS3 That Segregates with Schizophrenia in a Small Family Leads to Protein Aggregation.

Mol Neuropsychiatry 2016 Oct 27;2(3):133-144. Epub 2016 Jul 27.

Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Md., USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109994PMC
October 2016

Dopamine D2L Receptor Is Required for Visual Discrimination and Reversal Learning.

Mol Neuropsychiatry 2016 Oct 21;2(3):124-132. Epub 2016 Jul 21.

Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109995PMC
October 2016

Infection and inflammation in schizophrenia and bipolar disorder.

Neurosci Res 2017 Feb 14;115:59-63. Epub 2016 Nov 14.

Department of Mental Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21287, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neures.2016.11.002DOI Listing
February 2017

Abnormal wake/sleep pattern in a novel gain-of-function model of DISC1.

Neurosci Res 2016 Nov 26;112:63-69. Epub 2016 Jun 26.

Department of Psychiatry, Johns Hopkins University School of Medicine, United States. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077691PMC
http://dx.doi.org/10.1016/j.neures.2016.06.006DOI Listing
November 2016

Neuregulin 3 Knockout Mice Exhibit Behaviors Consistent with Psychotic Disorders.

Mol Neuropsychiatry 2016 Jul 20;2(2):79-87. Epub 2016 May 20.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Md., USA; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Md., USA.

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http://dx.doi.org/10.1159/000445836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996025PMC
July 2016

Cell Type-Specific Effects of Mutant DISC1: A Proteomics Study.

Mol Neuropsychiatry 2016 May 1;2(1):28-36. Epub 2016 Apr 1.

Departments of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Md., USA; Departments of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, Md., USA; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Md., USA; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md., USA.

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http://dx.doi.org/10.1159/000444587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996005PMC
May 2016

Oxidative stress and inflammation in schizophrenia.

Schizophr Res 2016 09 6;176(1):1-2. Epub 2016 Jul 6.

Johns Hopkins School of Medicine, Psychiatry and Neuroscience, 600 N. Wolfe St., 21287 Baltimore, MD, U.S.A.

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http://dx.doi.org/10.1016/j.schres.2016.06.014DOI Listing
September 2016

Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research.

Biol Psychiatry 2016 07;80(2):84-86

Department of Psychiatry, University Neuropsychiatric Institute, University of Utah Health Sciences Center, Salt Lake City, Utah.

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http://dx.doi.org/10.1016/j.biopsych.2016.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150945PMC
July 2016

Nucleus accumbens dopamine D2-receptor expressing neurons control behavioral flexibility in a place discrimination task in the IntelliCage.

Learn Mem 2016 07 17;23(7):359-64. Epub 2016 Jun 17.

Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan

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http://dx.doi.org/10.1101/lm.042507.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918782PMC
July 2016

A critical period of vulnerability to adolescent stress: epigenetic mediators in mesocortical dopaminergic neurons.

Hum Mol Genet 2016 Apr 28;25(7):1370-81. Epub 2016 Jan 28.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 3-166A, Baltimore, MD 21287, USA

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787906PMC
April 2016

Dimensional assessment of behavioral changes in the cuprizone short-term exposure model for psychosis.

Neurosci Res 2016 Jun 8;107:70-74. Epub 2016 Feb 8.

Department of Psychiatry, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.neures.2016.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884492PMC
June 2016

The potential of DISC1 protein as a therapeutic target for mental illness.

Expert Opin Ther Targets 2016 06 15;20(6):641-3. Epub 2016 Feb 15.

b Center for Human Disease Modeling and Departments of Cell Biology and Pediatrics , Duke University School of Medicine , Durham , NC , USA.

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http://dx.doi.org/10.1517/14728222.2016.1146694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476421PMC
June 2016

Schizophrenia.

Lancet 2016 Jul 15;388(10039):86-97. Epub 2016 Jan 15.

Department of Economics, School of Business and Social Science, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1016/S0140-6736(15)01121-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940219PMC
July 2016

Accelerating stem cell trials for Alzheimer's disease.

Lancet Neurol 2016 02 17;15(2):219-230. Epub 2015 Dec 17.

Duke Institute for Brain Sciences, Duke University, Durham, NC, USA; Psychiatry Department, Duke University, Durham, NC, USA. Electronic address:

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February 2016

Implications for reactive oxygen species in schizophrenia pathogenesis.

Schizophr Res 2016 09 15;176(1):52-71. Epub 2015 Nov 15.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 3-166, Baltimore, MD 21287, USA. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2015.06.022DOI Listing
September 2016

Impaired hippocampal activity at the goal zone on the place preference task in a DISC1 mouse model.

Neurosci Res 2016 May 20;106:70-3. Epub 2015 Oct 20.

Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan. Electronic address:

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May 2016

Increased stereotypy in conditional Cxcr4 knockout mice.

Neurosci Res 2016 Apr 13;105:75-9. Epub 2015 Oct 13.

Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States. Electronic address:

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http://dx.doi.org/10.1016/j.neures.2015.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833716PMC
April 2016

Sequence of Molecular Events during the Maturation of the Developing Mouse Prefrontal Cortex.

Mol Neuropsychiatry 2015 Jul 9;1(2):94-104. Epub 2015 Jun 9.

Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596535PMC
July 2015