Publications by authors named "Akiko Iwasaki"

100Publications

Commensal Microbiota Modulation of Natural Resistance to Virus Infection.

Cell 2020 Nov 13. Epub 2020 Nov 13.

Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.10.047DOI Listing
November 2020

Interferon deficiency can lead to severe COVID.

Nature 2020 11;587(7834):374-376

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http://dx.doi.org/10.1038/d41586-020-03070-1DOI Listing
November 2020

Why and How Vaccines Work.

Cell 2020 10;183(2):290-295

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT 06520, USA; Department of Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT 06520, USA; Yale Institute for Global Health, Yale University, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1016/j.cell.2020.09.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560117PMC
October 2020

What reinfections mean for COVID-19.

Authors:
Akiko Iwasaki

Lancet Infect Dis 2020 Oct 12. Epub 2020 Oct 12.

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA; Department of Molecular Cellular and Developmental Biology, Yale University, New Haven, CT 06510, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(20)30783-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550040PMC
October 2020

[Meningeal lymphatics, a potential target for the treatment of brain tumors].

Med Sci (Paris) 2020 Aug-Sep;36(8-9):709-713. Epub 2020 Aug 21.

Department of immunobiology, Yale university school of medicine, New Haven, CT, États-Unis - Howard Hughes medical institute, Chevy Chase, MD, États-Unis.

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http://dx.doi.org/10.1051/medsci/2020141DOI Listing
November 2020

The Role of Immune Factors in Shaping Fetal Neurodevelopment.

Annu Rev Cell Dev Biol 2020 Oct 28;36:441-468. Epub 2020 Jul 28.

Department of Immunobiology, Yale School of Medicine, Yale University, New Haven, Connecticut 06519, USA.

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http://dx.doi.org/10.1146/annurev-cellbio-021120-033518DOI Listing
October 2020

mA Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development.

Immunity 2020 Jun 3;52(6):1007-1021.e8. Epub 2020 Jun 3.

Section of Hematology, Yale Cancer Center and Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA; Yale Stem Cell Center and Yale RNA Center, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408742PMC
June 2020

Inflammasomes and Pyroptosis as Therapeutic Targets for COVID-19.

J Immunol 2020 07 3;205(2):307-312. Epub 2020 Jun 3.

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520;

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http://dx.doi.org/10.4049/jimmunol.2000513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343621PMC
July 2020

Type I and Type III Interferons - Induction, Signaling, Evasion, and Application to Combat COVID-19.

Cell Host Microbe 2020 06 27;27(6):870-878. Epub 2020 May 27.

Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA; Department of Molecular Cellular and Developmental Biology, Yale University School of Medicine, New Haven, CT, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2020.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255347PMC
June 2020

Contributions of maternal and fetal antiviral immunity in congenital disease.

Science 2020 05;368(6491):608-612

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1126/science.aaz1960DOI Listing
May 2020

The potential danger of suboptimal antibody responses in COVID-19.

Nat Rev Immunol 2020 06;20(6):339-341

Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1038/s41577-020-0321-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187142PMC
June 2020

Why does Japan have so few cases of COVID-19?

EMBO Mol Med 2020 05 28;12(5):e12481. Epub 2020 Apr 28.

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.

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http://dx.doi.org/10.15252/emmm.202012481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207161PMC
May 2020

Antidote to toxic principal investigators.

Authors:
Akiko Iwasaki

Nat Med 2020 04;26(4):457

Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1038/s41591-020-0831-6DOI Listing
April 2020

Seasonality of Respiratory Viral Infections.

Annu Rev Virol 2020 09 20;7(1):83-101. Epub 2020 Mar 20.

Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA; email:

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http://dx.doi.org/10.1146/annurev-virology-012420-022445DOI Listing
September 2020

Cutting Edge: The Use of Topical Aminoglycosides as an Effective Pull in "Prime and Pull" Vaccine Strategy.

J Immunol 2020 04 2;204(7):1703-1707. Epub 2020 Mar 2.

Howard Hughes Medical Institute, Chevy Chase, MD 20815;

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http://dx.doi.org/10.4049/jimmunol.1900462DOI Listing
April 2020

VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours.

Nature 2020 01 15;577(7792):689-694. Epub 2020 Jan 15.

Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1038/s41586-019-1912-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100608PMC
January 2020

RIG-I Recognition of RNA Targets: The Influence of Terminal Base Pair Sequence and Overhangs on Affinity and Signaling.

Cell Rep 2019 12;29(12):3807-3815.e3

Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520, USA; Howard Hughes Medical Institute, Yale University, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.11.052DOI Listing
December 2019

Intratumoral delivery of RIG-I agonist SLR14 induces robust antitumor responses.

J Exp Med 2019 12 10;216(12):2854-2868. Epub 2019 Oct 10.

Department of Immunobiology, Yale University School of Medicine, New Haven, CT

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http://dx.doi.org/10.1084/jem.20190801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888973PMC
December 2019

Reply to Iñiguez et al.: ERVmap is a validated approach to mapping proviral endogenous retroviruses in the human genome.

Proc Natl Acad Sci U S A 2019 10 8;116(43):21352-21353. Epub 2019 Oct 8.

Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520;

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http://dx.doi.org/10.1073/pnas.1908504116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815117PMC
October 2019

Murine Leukemia Virus Exploits Innate Sensing by Toll-Like Receptor 7 in B-1 Cells To Establish Infection and Locally Spread in Mice.

J Virol 2019 11 15;93(21). Epub 2019 Oct 15.

Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut, USA

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http://dx.doi.org/10.1128/JVI.00930-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803250PMC
November 2019

Why we need to increase diversity in the immunology research community.

Authors:
Akiko Iwasaki

Nat Immunol 2019 09;20(9):1085-1088

Department of Immunobiology, Yale School of Medicine, and Department of Molecular Cellular and Developmental Biology, Yale University, New Haven, CT, USA.

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http://dx.doi.org/10.1038/s41590-019-0470-6DOI Listing
September 2019

Successful application of prime and pull strategy for a therapeutic HSV vaccine.

NPJ Vaccines 2019 1;4:33. Epub 2019 Aug 1.

3Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6073 USA.

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http://dx.doi.org/10.1038/s41541-019-0129-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671986PMC
August 2019

Human APOBEC3G Prevents Emergence of Infectious Endogenous Retrovirus in Mice.

J Virol 2019 10 30;93(20). Epub 2019 Sep 30.

Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA

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http://dx.doi.org/10.1128/JVI.00728-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798113PMC
October 2019

Rapid temporal improvement of pembrolizumab-induced pneumonitis using the anti-TNF-α antibody infliximab.

Drug Discov Ther 2019 Jul 28;13(3):164-167. Epub 2019 Jun 28.

Department of Respiratory Medicine, The University of Tokyo.

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http://dx.doi.org/10.5582/ddt.2019.01032DOI Listing
July 2019

Migrant memory B cells secrete luminal antibody in the vagina.

Nature 2019 07 12;571(7763):122-126. Epub 2019 Jun 12.

Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1038/s41586-019-1285-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609483PMC
July 2019

Low ambient humidity impairs barrier function and innate resistance against influenza infection.

Proc Natl Acad Sci U S A 2019 05 13;116(22):10905-10910. Epub 2019 May 13.

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1902840116
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http://dx.doi.org/10.1073/pnas.1902840116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561219PMC
May 2019

Monocytes Inadequately Fill In for Meningeal Macrophages.

Trends Immunol 2019 06 6;40(6):463-465. Epub 2019 May 6.

Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519, USA; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.it.2019.04.004DOI Listing
June 2019

YTHDF1 Control of Dendritic Cell Cross-Priming as a Possible Target of Cancer Immunotherapy.

Biochemistry 2019 04 3;58(15):1945-1946. Epub 2019 Apr 3.

Department of Immunobiology , Yale School of Medicine , New Haven , Connecticut 06519 , United States.

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http://dx.doi.org/10.1021/acs.biochem.9b00200DOI Listing
April 2019

Aedes aegypti AgBR1 antibodies modulate early Zika virus infection of mice.

Nat Microbiol 2019 06 11;4(6):948-955. Epub 2019 Mar 11.

Section of Infectious Diseases, Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT, USA.

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http://www.nature.com/articles/s41564-019-0385-x
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http://dx.doi.org/10.1038/s41564-019-0385-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533137PMC
June 2019

RIG-I Selectively Discriminates against 5'-Monophosphate RNA.

Cell Rep 2019 02;26(8):2019-2027.e4

Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06511, USA; Howard Hughes Medical Institute, Yale University, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.01.107DOI Listing
February 2019

The Combination of MEK Inhibitor With Immunomodulatory Antibodies Targeting Programmed Death 1 and Programmed Death Ligand 1 Results in Prolonged Survival in Kras/p53-Driven Lung Cancer.

J Thorac Oncol 2019 06 13;14(6):1046-1060. Epub 2019 Feb 13.

Section of Medical Oncology, Department of Internal Medicine, Yale Comprehensive Cancer Center, Yale School of Medicine, New Haven, Connecticut; Developmental Therapeutics Translational Research Program, Yale Comprehensive Cancer Center, New Haven, Connecticut. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2019.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542636PMC
June 2019

The Lupus Susceptibility Locus Sgp3 Encodes the Suppressor of Endogenous Retrovirus Expression SNERV.

Immunity 2019 02 29;50(2):334-347.e9. Epub 2019 Jan 29.

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.12.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382577PMC
February 2019

Apobec3A maintains HIV-1 latency through recruitment of epigenetic silencing machinery to the long terminal repeat.

Proc Natl Acad Sci U S A 2019 02 22;116(6):2282-2289. Epub 2019 Jan 22.

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520;

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http://dx.doi.org/10.1073/pnas.1819386116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369738PMC
February 2019

ERVmap analysis reveals genome-wide transcription of human endogenous retroviruses.

Proc Natl Acad Sci U S A 2018 12 19;115(50):12565-12572. Epub 2018 Nov 19.

Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520;

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http://dx.doi.org/10.1073/pnas.1814589115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294949PMC
December 2018

Interferons and Proinflammatory Cytokines in Pregnancy and Fetal Development.

Immunity 2018 09;49(3):397-412

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152841PMC
September 2018

An Antiviral Branch of the IL-1 Signaling Pathway Restricts Immune-Evasive Virus Replication.

Mol Cell 2018 09 9;71(5):825-840.e6. Epub 2018 Aug 9.

Division of Gastroenterology, Boston Children's Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411291PMC
September 2018

The interaction between IKKα and LC3 promotes type I interferon production through the TLR9-containing LAPosome.

Sci Signal 2018 05 1;11(528). Epub 2018 May 1.

Department of Immunobiology, Yale University, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1126/scisignal.aan4144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462218PMC
May 2018

A minimal RNA ligand for potent RIG-I activation in living mice.

Sci Adv 2018 02 21;4(2):e1701854. Epub 2018 Feb 21.

Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1126/sciadv.1701854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821489PMC
February 2018

Aging impairs both primary and secondary RIG-I signaling for interferon induction in human monocytes.

Sci Signal 2017 Dec 12;10(509). Epub 2017 Dec 12.

Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1126/scisignal.aan2392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429941PMC
December 2017

Antiviral CD8 T cells induce Zika-virus-associated paralysis in mice.

Nat Microbiol 2018 02 20;3(2):141-147. Epub 2017 Nov 20.

Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1038/s41564-017-0060-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780207PMC
February 2018

Zika virus targets blood monocytes.

Nat Microbiol 2017 11;2(11):1460-1461

Department of Immunobiology, Yale University School of Medicine, New Haven, CT, 06520, USA.

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http://dx.doi.org/10.1038/s41564-017-0049-7DOI Listing
November 2017

RAB15 empowers dendritic cells to drive antiviral immunity.

Sci Immunol 2017 Jul;2(13)

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1126/sciimmunol.aan6448DOI Listing
July 2017

Sensing Self and Foreign Circular RNAs by Intron Identity.

Mol Cell 2017 Jul 15;67(2):228-238.e5. Epub 2017 Jun 15.

Center for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.05.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610545PMC
July 2017

Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.

Nat Immunol 2017 Aug 12;18(8):899-910. Epub 2017 Jun 12.

Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1038/ni.3767DOI Listing
August 2017

IRE1α promotes viral infection by conferring resistance to apoptosis.

Sci Signal 2017 Jun 6;10(482). Epub 2017 Jun 6.

Department of Immunobiology, Yale University, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1126/scisignal.aai7814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535312PMC
June 2017

Gastric Cancer With Primitive Enterocyte Phenotype: An Aggressive Subgroup of Intestinal-type Adenocarcinoma.

Am J Surg Pathol 2017 Jul;41(7):989-997

Departments of *Pathology ‡Gastrointestinal Surgery, Graduate School of Medicine †Genome Science Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1097/PAS.0000000000000869DOI Listing
July 2017

Fetal Growth Restriction Caused by Sexual Transmission of Zika Virus in Mice.

J Infect Dis 2017 06;215(11):1720-1724

Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine.

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https://academic.oup.com/jid/article/215/11/1720/3786455
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http://dx.doi.org/10.1093/infdis/jix204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853330PMC
June 2017

TAM Receptors Are Not Required for Zika Virus Infection in Mice.

Cell Rep 2017 04;19(3):558-568

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.03.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485843PMC
April 2017

Zika virus causes testicular atrophy.

Sci Adv 2017 Feb 22;3(2):e1602899. Epub 2017 Feb 22.

Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.

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http://dx.doi.org/10.1126/sciadv.1602899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321463PMC
February 2017

β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares.

Cell Rep 2017 02;18(9):2077-2087

Section of Comparative Medicine, Yale School of Medicine, New Haven, CT 06520, USA; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA; Yale Center for Research on Aging, Yale School of Medicine, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527297PMC
February 2017

Immune Regulation of Antibody Access to Neuronal Tissues.

Authors:
Akiko Iwasaki

Trends Mol Med 2017 03 7;23(3):227-245. Epub 2017 Feb 7.

Howard Hughes Medical Institute, Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2017.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626569PMC
March 2017

Early local immune defences in the respiratory tract.

Nat Rev Immunol 2017 01 28;17(1):7-20. Epub 2016 Nov 28.

Department of Immunobiology, Yale School of Medicine. New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1038/nri.2016.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480291PMC
January 2017

CD301b+ dendritic cells stimulate tissue-resident memory CD8+ T cells to protect against genital HSV-2.

Nat Commun 2016 11 9;7:13346. Epub 2016 Nov 9.

Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520 USA.

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http://dx.doi.org/10.1038/ncomms13346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105190PMC
November 2016

CD301b dendritic cells suppress T follicular helper cells and antibody responses to protein antigens.

Elife 2016 Sep 22;5. Epub 2016 Sep 22.

Department of Immunobiology, Yale University School of Medicine, New Haven, United States.

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http://dx.doi.org/10.7554/eLife.17979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033605PMC
September 2016

CD301b(+) Mononuclear Phagocytes Maintain Positive Energy Balance through Secretion of Resistin-like Molecule Alpha.

Immunity 2016 09 23;45(3):583-596. Epub 2016 Aug 23.

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815-6789, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033704PMC
September 2016

Vaginal Exposure to Zika Virus during Pregnancy Leads to Fetal Brain Infection.

Cell 2016 Aug;166(5):1247-1256.e4

Department of Immunobiology, Yale University School of Medicine, New Haven, CT, 06520 USA; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, 06520 USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006689PMC
August 2016

Two interferon-independent double-stranded RNA-induced host defense strategies suppress the common cold virus at warm temperature.

Proc Natl Acad Sci U S A 2016 07 11;113(30):8496-501. Epub 2016 Jul 11.

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520; Howard Hughes Medical Institute, New Haven, CT 06520

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http://dx.doi.org/10.1073/pnas.1601942113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968739PMC
July 2016

CD301b+ Macrophages Are Essential for Effective Skin Wound Healing.

J Invest Dermatol 2016 09 7;136(9):1885-1891. Epub 2016 Jun 7.

Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA; Department of Dermatology, Yale School of Medicine, New Haven, Connecticut, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.05.107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727894PMC
September 2016

Viral Spread to Enteric Neurons Links Genital HSV-1 Infection to Toxic Megacolon and Lethality.

Cell Host Microbe 2016 Jun;19(6):788-99

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2016.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902295PMC
June 2016

Access of protective antiviral antibody to neuronal tissues requires CD4 T-cell help.

Nature 2016 05 18;533(7604):552-6. Epub 2016 May 18.

Howard Hughes Medical Institute, Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1038/nature17979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883597PMC
May 2016

Exploiting Mucosal Immunity for Antiviral Vaccines.

Authors:
Akiko Iwasaki

Annu Rev Immunol 2016 05;34:575-608

Howard Hughes Medical Institute, Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520; email:

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http://dx.doi.org/10.1146/annurev-immunol-032414-112315DOI Listing
May 2016

Antiviral responses of inbred mice.

Authors:
Akiko Iwasaki

Nat Rev Immunol 2016 06 25;16(6):339. Epub 2016 Apr 25.

Howard Hughes Medical Institute, Department of Immunobiology, Yale University School of Medicine, 300 Cedar Street, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1038/nri.2016.44DOI Listing
June 2016

O-linked sugars sound the alarm.

Nat Immunol 2016 Feb;17(2):119-20

Department of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/ni.3364DOI Listing
February 2016

Autophagy Snuffs a Macrophage's Inner Fire.

Cell Host Microbe 2016 Jan;19(1):9-11

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2015.12.015DOI Listing
January 2016