Akihiro Nomura

Akihiro Nomura

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Akihiro Nomura

Publications by authors named "Akihiro Nomura"

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First case of sitosterolemia caused by double heterozygous mutations in ABCG5 and ABCG8 genes.

J Clin Lipidol 2018 Sep - Oct;12(5):1164-1168.e4. Epub 2018 Jun 20.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.jacl.2018.06.003DOI Listing
October 2019

Oligogenic familial hypercholesterolemia, LDL cholesterol, and coronary artery disease.

J Clin Lipidol 2018 Nov - Dec;12(6):1436-1444. Epub 2018 Aug 23.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.jacl.2018.08.006DOI Listing
October 2019

Reply to the Editor- Patients with atrial fibrillation with hypertrophic cardiomyopathy: Do we need new stroke risk stratification?

Heart Rhythm 2019 Aug 4;16(8):e56-e57. Epub 2019 Apr 4.

Department of Cardiology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2019.04.001DOI Listing
August 2019

Effect of hypertrophic cardiomyopathy on the prediction of thromboembolism in patients with nonvalvular atrial fibrillation.

Heart Rhythm 2019 Jun 29;16(6):829-837. Epub 2018 Nov 29.

Department of Cardiovascular and Internal Medicine Kanazawa University Graduate School of Medical Science, Kanazawa, Japan; Department of Human Sciences, Osaka University of Human Sciences, Settsu, Japan.

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http://dx.doi.org/10.1016/j.hrthm.2018.11.029DOI Listing
June 2019

Study Protocol for the Effects of Artificial Intelligence (AI)-Supported Automated Nutritional Intervention on Glycemic Control in Patients with Type 2 Diabetes Mellitus.

Diabetes Ther 2019 Jun 15;10(3):1151-1161. Epub 2019 Mar 15.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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http://dx.doi.org/10.1007/s13300-019-0595-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531593PMC
June 2019

Functional analysis of KCNH2 gene mutations of type 2 long QT syndrome in larval zebrafish using microscopy and electrocardiography.

Heart Vessels 2019 Jan 25;34(1):159-166. Epub 2018 Jul 25.

Department of Cardiovascular and Internal Medicine, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8640, Japan.

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http://dx.doi.org/10.1007/s00380-018-1231-4DOI Listing
January 2019

Clinical whole exome sequencing in severe hypertriglyceridemia.

Clin Chim Acta 2019 Jan 30;488:31-39. Epub 2018 Oct 30.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S00098981183056
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http://dx.doi.org/10.1016/j.cca.2018.10.041DOI Listing
January 2019

Post-prandial Remnant Lipoprotein Metabolism in Sitosterolemia.

J Atheroscler Thromb 2018 Dec 12;25(12):1188-1195. Epub 2018 Jul 12.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine.

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http://dx.doi.org/10.5551/jat.44768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249359PMC
December 2018

Serum triglycerides predict first cardiovascular events in diabetic patients with hypercholesterolemia and retinopathy.

Eur J Prev Cardiol 2018 11 30;25(17):1852-1860. Epub 2018 Aug 30.

1 Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Japan.

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http://dx.doi.org/10.1177/2047487318796989DOI Listing
November 2018

Mendelian randomization: Its impact on cardiovascular disease.

J Cardiol 2018 10 22;72(4):307-313. Epub 2018 May 22.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.jjcc.2018.04.007DOI Listing
October 2018

Phenotype and Prognosis of the Lamin A/C Gene (LMNA) Mutation Carriers in Japan.

Circ J 2018 10 21;82(11):2699-2700. Epub 2018 Sep 21.

Department of Cardiovascular and Internal Medicine, Kanazawa University, Graduate School of Medical Science.

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http://dx.doi.org/10.1253/circj.CJ-18-0954DOI Listing
October 2018

Oral Fat Tolerance Test for Sitosterolemia and Familial Hypercholesterolemia: A Study Protocol.

J Atheroscler Thromb 2018 Aug 20;25(8):741-746. Epub 2018 Jan 20.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine.

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http://dx.doi.org/10.5551/jat.42960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099073PMC
August 2018

Paradoxical impact of decreased low-density lipoprotein cholesterol level at baseline on the long-term prognosis in patients with acute coronary syndrome.

Heart Vessels 2018 Jul 29;33(7):695-705. Epub 2017 Dec 29.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, 13-1, Takara-machi, Kanazawa, Ishikawa, 920-8640, Japan.

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http://dx.doi.org/10.1007/s00380-017-1111-3DOI Listing
July 2018

J Waves for Predicting Cardiac Events in Hypertrophic Cardiomyopathy.

JACC Clin Electrophysiol 2017 10 28;3(10):1136-1142. Epub 2017 Jun 28.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.jacep.2017.03.010DOI Listing
October 2017

Ternary complex of human RORγ ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment.

Genes Cells 2017 Jun 11;22(6):535-551. Epub 2017 May 11.

Pharmaceutical Frontier Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc., 1-13-2, Fukuura, Kanazawa-Ku, Yokohama, Kanagawa, 236-0004, Japan.

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http://dx.doi.org/10.1111/gtc.12494DOI Listing
June 2017

CNT Sheet Air Electrode for the Development of Ultra-High Cell Capacity in Lithium-Air Batteries.

Sci Rep 2017 04 5;7:45596. Epub 2017 Apr 5.

GREEN, National Institute for Materials Science, 1-1 Namiki, Tsukuba 305-0044, Japan.

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http://dx.doi.org/10.1038/srep45596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381228PMC
April 2017

ANGPTL3 Deficiency and Protection Against Coronary Artery Disease.

J Am Coll Cardiol 2017 Apr 3;69(16):2054-2063. Epub 2017 Apr 3.

Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2017.02.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404817PMC
April 2017

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.

Authors:
Nathalie Chami Ming-Huei Chen Andrew J Slater John D Eicher Evangelos Evangelou Salman M Tajuddin Latisha Love-Gregory Tim Kacprowski Ursula M Schick Akihiro Nomura Ayush Giri Samuel Lessard Jennifer A Brody Claudia Schurmann Nathan Pankratz Lisa R Yanek Ani Manichaikul Raha Pazoki Evelin Mihailov W David Hill Laura M Raffield Amber Burt Traci M Bartz Diane M Becker Lewis C Becker Eric Boerwinkle Jette Bork-Jensen Erwin P Bottinger Michelle L O'Donoghue David R Crosslin Simon de Denus Marie-Pierre Dubé Paul Elliott Gunnar Engström Michele K Evans James S Floyd Myriam Fornage He Gao Andreas Greinacher Vilmundur Gudnason Torben Hansen Tamara B Harris Caroline Hayward Jussi Hernesniemi Heather M Highland Joel N Hirschhorn Albert Hofman Marguerite R Irvin Mika Kähönen Ethan Lange Lenore J Launer Terho Lehtimäki Jin Li David C M Liewald Allan Linneberg Yongmei Liu Yingchang Lu Leo-Pekka Lyytikäinen Reedik Mägi Rasika A Mathias Olle Melander Andres Metspalu Nina Mononen Mike A Nalls Deborah A Nickerson Kjell Nikus Chris J O'Donnell Marju Orho-Melander Oluf Pedersen Astrid Petersmann Linda Polfus Bruce M Psaty Olli T Raitakari Emma Raitoharju Melissa Richard Kenneth M Rice Fernando Rivadeneira Jerome I Rotter Frank Schmidt Albert Vernon Smith John M Starr Kent D Taylor Alexander Teumer Betina H Thuesen Eric S Torstenson Russell P Tracy Ioanna Tzoulaki Neil A Zakai Caterina Vacchi-Suzzi Cornelia M van Duijn Frank J A van Rooij Mary Cushman Ian J Deary Digna R Velez Edwards Anne-Claire Vergnaud Lars Wallentin Dawn M Waterworth Harvey D White James G Wilson Alan B Zonderman Sekar Kathiresan Niels Grarup Tõnu Esko Ruth J F Loos Leslie A Lange Nauder Faraday Nada A Abumrad Todd L Edwards Santhi K Ganesh Paul L Auer Andrew D Johnson Alexander P Reiner Guillaume Lettre

Am J Hum Genet 2016 Jul 23;99(1):8-21. Epub 2016 Jun 23.

Department of Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada; Montreal Heart Institute, Montréal, QC H1T 1C8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005438PMC
July 2016

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals.

Authors:
John D Eicher Nathalie Chami Tim Kacprowski Akihiro Nomura Ming-Huei Chen Lisa R Yanek Salman M Tajuddin Ursula M Schick Andrew J Slater Nathan Pankratz Linda Polfus Claudia Schurmann Ayush Giri Jennifer A Brody Leslie A Lange Ani Manichaikul W David Hill Raha Pazoki Paul Elliot Evangelos Evangelou Ioanna Tzoulaki He Gao Anne-Claire Vergnaud Rasika A Mathias Diane M Becker Lewis C Becker Amber Burt David R Crosslin Leo-Pekka Lyytikäinen Kjell Nikus Jussi Hernesniemi Mika Kähönen Emma Raitoharju Nina Mononen Olli T Raitakari Terho Lehtimäki Mary Cushman Neil A Zakai Deborah A Nickerson Laura M Raffield Rakale Quarells Cristen J Willer Gina M Peloso Goncalo R Abecasis Dajiang J Liu Panos Deloukas Nilesh J Samani Heribert Schunkert Jeanette Erdmann Myriam Fornage Melissa Richard Jean-Claude Tardif John D Rioux Marie-Pierre Dube Simon de Denus Yingchang Lu Erwin P Bottinger Ruth J F Loos Albert Vernon Smith Tamara B Harris Lenore J Launer Vilmundur Gudnason Digna R Velez Edwards Eric S Torstenson Yongmei Liu Russell P Tracy Jerome I Rotter Stephen S Rich Heather M Highland Eric Boerwinkle Jin Li Ethan Lange James G Wilson Evelin Mihailov Reedik Mägi Joel Hirschhorn Andres Metspalu Tõnu Esko Caterina Vacchi-Suzzi Mike A Nalls Alan B Zonderman Michele K Evans Gunnar Engström Marju Orho-Melander Olle Melander Michelle L O'Donoghue Dawn M Waterworth Lars Wallentin Harvey D White James S Floyd Traci M Bartz Kenneth M Rice Bruce M Psaty J M Starr David C M Liewald Caroline Hayward Ian J Deary Andreas Greinacher Uwe Völker Thomas Thiele Henry Völzke Frank J A van Rooij André G Uitterlinden Oscar H Franco Abbas Dehghan Todd L Edwards Santhi K Ganesh Sekar Kathiresan Nauder Faraday Paul L Auer Alex P Reiner Guillaume Lettre Andrew D Johnson

Am J Hum Genet 2016 Jul 23;99(1):40-55. Epub 2016 Jun 23.

Population Sciences Branch, National Heart Lung and Blood Institute, The Framingham Heart Study, Framingham, MA 01702, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005441PMC
July 2016

Usefulness of Electrocardiographic Voltage to Determine Myocardial Fibrosis in Hypertrophic Cardiomyopathy.

Am J Cardiol 2016 Feb 19;117(3):443-9. Epub 2015 Nov 19.

Division of Cardiovascular Medicine, Graduate School of Medicine, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.amjcard.2015.11.015DOI Listing
February 2016

Electrocardiographic QRS Fragmentation as a Marker for Myocardial Fibrosis in Hypertrophic Cardiomyopathy.

J Cardiovasc Electrophysiol 2015 Oct 11;26(10):1081-7. Epub 2015 Aug 11.

Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.

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http://dx.doi.org/10.1111/jce.12742DOI Listing
October 2015

Can next-generation sequencing replace sanger sequencing for screening genetic variants?

Circ J 2014 4;78(12):2845-7. Epub 2014 Nov 4.

Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine.

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http://dx.doi.org/10.1253/circj.cj-14-1144DOI Listing
July 2015

Successful endovascular treatment for high take off aorto-iliac occlusive disease.

Intern Med 2015 15;54(8):921-4. Epub 2015 Apr 15.

Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Japan.

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http://dx.doi.org/10.2169/internalmedicine.54.2920DOI Listing
July 2015

Right ventricular hypertrophy is associated with cardiovascular events in hypertrophic cardiomyopathy: evidence from study with magnetic resonance imaging.

Can J Cardiol 2015 Jun 24;31(6):702-8. Epub 2015 Jan 24.

Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan; Research and Education Center for Innovative and Preventive Medicine, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.cjca.2014.12.036DOI Listing
June 2015

Enhanced formaldehyde-vapor adsorption capacity of polymeric amine-incorporated aminosilicas.

Chemistry 2014 May 3;20(21):6381-90. Epub 2014 Apr 3.

School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Drive, Atlanta, GA 30332-0100 (USA), Fax: (+1) 404-894-2866.

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http://dx.doi.org/10.1002/chem.201304954DOI Listing
May 2014

Amine-functionalized porous silicas as adsorbents for aldehyde abatement.

ACS Appl Mater Interfaces 2013 Jun 7;5(12):5569-77. Epub 2013 Jun 7.

School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Drive, Atlanta, Georgia 30332-0100, USA.

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http://pubs.acs.org/doi/10.1021/am400810s
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http://dx.doi.org/10.1021/am400810sDOI Listing
June 2013

Synthesis and characterization of polystyrene brushes for organic thin film transistors.

J Nanosci Nanotechnol 2012 May;12(5):4137-41

Department of Chemistry, and Chemistry Institute for Functional Materials, Pusan National University, Busan 609-735, Republic of Korea.

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http://dx.doi.org/10.1166/jnn.2012.5930DOI Listing
May 2012

Overexpression of GATA-3 protects against the development of hypersensitivity pneumonitis.

Am J Respir Crit Care Med 2007 Nov 23;176(10):1015-25. Epub 2007 Aug 23.

Department of Respiratory Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1164/rccm.200612-1887OCDOI Listing
November 2007

The effect of smoking-related hyperhomocysteinemia on spirometric declines in chronic obstructive pulmonary disease in elderly Japanese.

Arch Gerontol Geriatr 2006 Mar-Apr;42(2):117-24. Epub 2005 Aug 26.

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.

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http://dx.doi.org/10.1016/j.archger.2005.06.003DOI Listing
April 2007

Effect of inhaled steroids on increased collagen synthesis in asthma.

Respiration 2007 6;74(2):154-8. Epub 2006 Feb 6.

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.

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http://search.proquest.com/openview/9ba9dd0db022344fb5d8bec7
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http://www.karger.com/doi/10.1159/000091390
Publisher Site
http://dx.doi.org/10.1159/000091390DOI Listing
April 2007

Niflumic acid and AG-1478 reduce cigarette smoke-induced mucin synthesis: the role of hCLCA1.

Chest 2007 Apr;131(4):1149-56

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan.

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http://dx.doi.org/10.1378/chest.06-2031DOI Listing
April 2007

Sleep stage determines the expression pattern of sleep apneas.

Intern Med 2007 1;46(1):45-8. Epub 2007 Jan 1.

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba.

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http://dx.doi.org/10.2169/internalmedicine.45.6014DOI Listing
January 2007

Anaerobic bacterial empyema accompanying intrathoracic gas formation in anorexia nervosa.

Int J Eat Disord 2006 Nov;39(7):621-3

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Japan.

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http://dx.doi.org/10.1002/eat.20275DOI Listing
November 2006

Association of phosphodiesterase 4D gene polymorphisms with chronic obstructive pulmonary disease: relationship to interleukin 13 gene polymorphism.

Int J Mol Med 2006 Nov;18(5):933-9

Department of Pulmonary Medicine, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences and University Hospital, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.

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November 2006

Transcription factors T-bet and GATA-3 regulate development of airway remodeling.

Am J Respir Crit Care Med 2006 Jul 13;174(2):142-51. Epub 2006 Apr 13.

Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305, Japan.

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http://dx.doi.org/10.1164/rccm.200601-079OCDOI Listing
July 2006

MMP14 gene polymorphisms in chronic obstructive pulmonary disease.

Int J Mol Med 2006 Apr;17(4):621-6

Department of Pulmonary Medicine, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences and University Hospital, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.

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April 2006

Suppression of eosinophilic airway inflammation by treatment with alpha-galactosylceramide.

Eur J Immunol 2005 Oct;35(10):2803-14

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Japan.

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http://dx.doi.org/10.1002/eji.200525994DOI Listing
October 2005

Role of 15-deoxy delta(12,14) prostaglandin J2 and Nrf2 pathways in protection against acute lung injury.

Am J Respir Crit Care Med 2005 Jun 4;171(11):1260-6. Epub 2005 Mar 4.

Department of Respiratory Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305, Japan.

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http://dx.doi.org/10.1164/rccm.200406-755OCDOI Listing
June 2005

Anti-inflammatory activity of creatine supplementation in endothelial cells in vitro.

Br J Pharmacol 2003 Jun;139(4):715-20

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, Tennoudai 1-1-1, Tsukuba, Ibaraki 305-8575, Japan.

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http://dx.doi.org/10.1038/sj.bjp.0705316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573908PMC
June 2003

Age-related changes in plasma orexin-A concentrations.

Exp Gerontol 2002 Aug-Sep;37(8-9):1127-30

Department of Respiratory Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennoudai Tsukuba, Ibaraki 305-8575, Japan.

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http://dx.doi.org/10.1016/s0531-5565(02)00092-xDOI Listing
October 2002

S-carboxymethylcysteine inhibits neutrophil activation mediated by N-formyl-methionyl-leucyl-phenylalanine.

Eur J Pharmacol 2002 Aug;449(1-2):183-9

Department of Respiratory Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Ten-nohdai, Tsukuba, Ibaraki 305-0006, Japan.

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http://dx.doi.org/10.1016/s0014-2999(02)01981-7DOI Listing
August 2002

Ebselen suppresses late airway responses and airway inflammation in guinea pigs.

Free Radic Biol Med 2002 Mar;32(5):454-64

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, Tennoudai 1-1-1, Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1016/s0891-5849(01)00825-5DOI Listing
March 2002

Involvement of thromboxane A(2) in airway mucous cells in asthma-related cough.

J Appl Physiol (1985) 2002 Feb;92(2):763-70

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.

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http://dx.doi.org/10.1152/jappl.2002.92.2.763DOI Listing
February 2002