Akihiro Nomura

Akihiro Nomura

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Akihiro Nomura

Publications by authors named "Akihiro Nomura"

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First case of sitosterolemia caused by double heterozygous mutations in ABCG5 and ABCG8 genes.

Authors:
Hayato Tada Akihiro Nomura Masakazu Yamagishi Masa-Aki Kawashiri

J Clin Lipidol 2018 Sep - Oct;12(5):1164-1168.e4. Epub 2018 Jun 20.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.jacl.2018.06.003DOI Listing
October 2019

Oligogenic familial hypercholesterolemia, LDL cholesterol, and coronary artery disease.

Authors:
Hayato Tada Masa-Aki Kawashiri Akihiro Nomura Ryota Teramoto Kazuyoshi Hosomichi Atsushi Nohara Akihiro Inazu Hiroshi Mabuchi Atsushi Tajima Masakazu Yamagishi

J Clin Lipidol 2018 Nov - Dec;12(6):1436-1444. Epub 2018 Aug 23.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.jacl.2018.08.006DOI Listing
October 2019

Impact of decreased ankle-brachial index on 30-day bleeding complications and long-term mortality in patients with acute coronary syndrome after percutaneous coronary intervention.

Authors:
Takuya Nakahashi Hayato Tada Kenji Sakata Yohei Yakuta Yoshihiro Tanaka Tadatsugu Gamou Akihiro Nomura Hidenobu Terai Yuki Horita Masatoshi Ikeda Masanobu Namura Masayuki Takamura Kenshi Hayashi Masakazu Yamagishi Masa-Aki Kawashiri

J Cardiol 2019 Aug 8;74(2):116-122. Epub 2019 Feb 8.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.jjcc.2019.01.008DOI Listing
August 2019

Reply to the Editor- Patients with atrial fibrillation with hypertrophic cardiomyopathy: Do we need new stroke risk stratification?

Authors:
Toyonobu Tsuda Akihiro Nomura Kenshi Hayashi

Heart Rhythm 2019 Aug 4;16(8):e56-e57. Epub 2019 Apr 4.

Department of Cardiology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2019.04.001DOI Listing
August 2019

Rare and Deleterious Mutations in ABCG5/ABCG8 Genes Contribute to Mimicking and Worsening of Familial Hypercholesterolemia Phenotype.

Authors:
Hayato Tada Hirofumi Okada Akihiro Nomura Satoshi Yashiro Atsushi Nohara Yasushi Ishigaki Masayuki Takamura Masa-Aki Kawashiri

Circ J 2019 Aug 20;83(9):1917-1924. Epub 2019 Jul 20.

Department of Cardiology, Kanazawa University Graduate School of Medicine.

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https://www.jstage.jst.go.jp/article/circj/83/9/83_CJ-19-031
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http://dx.doi.org/10.1253/circj.CJ-19-0317DOI Listing
August 2019

Comparing Telemedicine and Face-to-Face Consultation Based on the Standard Smoking Cessation Program for Nicotine Dependence: Protocol for a Randomized Controlled Trial.

Authors:
Tomoyuki Tanigawa Akihiro Nomura Maki Kuroda Tomoyasu Muto Eisuke Hida Kohta Satake

JMIR Res Protoc 2019 Jul 9;8(7):e12701. Epub 2019 Jul 9.

CureApp Institute, Karuizawa, Japan.

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http://dx.doi.org/10.2196/12701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647761PMC
July 2019

Effect of hypertrophic cardiomyopathy on the prediction of thromboembolism in patients with nonvalvular atrial fibrillation.

Authors:
Toyonobu Tsuda Kenshi Hayashi Noboru Fujino Tetsuo Konno Hayato Tada Akihiro Nomura Yoshihiro Tanaka Kenji Sakata Hiroshi Furusho Masayuki Takamura Masa-Aki Kawashiri Masakazu Yamagishi

Heart Rhythm 2019 Jun 29;16(6):829-837. Epub 2018 Nov 29.

Department of Cardiovascular and Internal Medicine Kanazawa University Graduate School of Medical Science, Kanazawa, Japan; Department of Human Sciences, Osaka University of Human Sciences, Settsu, Japan.

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http://dx.doi.org/10.1016/j.hrthm.2018.11.029DOI Listing
June 2019

Study Protocol for the Effects of Artificial Intelligence (AI)-Supported Automated Nutritional Intervention on Glycemic Control in Patients with Type 2 Diabetes Mellitus.

Authors:
Rie Oka Akihiro Nomura Ayaka Yasugi Mitsuhiro Kometani Yuko Gondoh Kenichi Yoshimura Takashi Yoneda

Diabetes Ther 2019 Jun 15;10(3):1151-1161. Epub 2019 Mar 15.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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http://dx.doi.org/10.1007/s13300-019-0595-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531593PMC
June 2019

Rare Protein-Truncating Variants in APOB, Lower Low-Density Lipoprotein Cholesterol, and Protection Against Coronary Heart Disease.

Authors:
Gina M Peloso Akihiro Nomura Amit V Khera Mark Chaffin Hong-Hee Won Diego Ardissino John Danesh Heribert Schunkert James G Wilson Nilesh Samani Jeanette Erdmann Ruth McPherson Hugh Watkins Danish Saleheen Shane McCarthy Tanya M Teslovich Joseph B Leader H Lester Kirchner Jaume Marrugat Atsushi Nohara Masa-Aki Kawashiri Hayato Tada Frederick E Dewey David J Carey Aris Baras Sekar Kathiresan

Circ Genom Precis Med 2019 May;12(5):e002376

Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (A.V.K., M.C., S.K.).

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http://dx.doi.org/10.1161/CIRCGEN.118.002376DOI Listing
May 2019

Quick sepsis-related organ failure assessment score as a possible predictor for in-hospital adverse events in infective endocarditis.

Authors:
Yudai Tamura Akihiro Nomura Shohei Yoshida Hayato Tada Kenji Sakata Kenji Iino Hiroshi Furusho Masayuki Takamura Hirofumi Takemura Masakazu Yamagishi Masa-Aki Kawashiri

Acute Med Surg 2019 Apr 19;6(2):138-144. Epub 2019 Feb 19.

Division of Cardiology Kanazawa University Hospital Kanazawa Japan.

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http://dx.doi.org/10.1002/ams2.393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442521PMC
April 2019

Clinical Efficacy of Telemedicine Compared to Face-to-Face Clinic Visits for Smoking Cessation: Multicenter Open-Label Randomized Controlled Noninferiority Trial.

Authors:
Akihiro Nomura Tomoyuki Tanigawa Tomoyasu Muto Takafumi Oga Yasushi Fukushima Arihiro Kiyosue Masaki Miyazaki Eisuke Hida Kohta Satake

J Med Internet Res 2019 04 26;21(4):e13520. Epub 2019 Apr 26.

CureApp Institute, Karuizawa, Japan.

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http://dx.doi.org/10.2196/13520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660118PMC
April 2019

Discovery of Second Generation RORĪ³ Inhibitors Composed of an Azole Scaffold.

Authors:
Masayuki Kotoku Takaki Maeba Shingo Fujioka Masahiro Yokota Noriyoshi Seki Keisuke Ito Yoshihiro Suwa Taku Ikenogami Kazuyuki Hirata Yasunori Hase Yoshiaki Katsuda Naoki Miyagawa Kojo Arita Kota Asahina Masato Noguchi Akihiro Nomura Satoki Doi Tsuyoshi Adachi Paul Crowe Haiyan Tao Scott Thacher Hiromasa Hashimoto Takayoshi Suzuki Makoto Shiozaki

J Med Chem 2019 Mar 1;62(5):2837-2842. Epub 2019 Mar 1.

Graduate School of Medical Science , Kyoto Prefectural University of Medicine , 1-5 Shimogamo-hangi-cho , Sakyo-ku , Kyoto 603-0823 , Japan.

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http://dx.doi.org/10.1021/acs.jmedchem.8b01567DOI Listing
March 2019

Randomized placebo-controlled double-blind phase II study of zaltoprofen for patients with diffuse-type and unresectable localized tenosynovial giant cell tumors: a study protocol.

Authors:
Akihiko Takeuchi Akihiro Nomura Norio Yamamoto Katsuhiro Hayashi Kentaro Igarashi Susumu Tandai Akira Kawai Akihiko Matsumine Shinji Miwa Yoshihiro Nishida Tomoki Nakamura Ryu Terauchi Manabu Hoshi Toshiyuki Kunisada Makoto Endo Kenichi Yoshimura Toshinori Murayama Hiroyuki Tsuchiya

BMC Musculoskelet Disord 2019 Feb 9;20(1):68. Epub 2019 Feb 9.

Department of Orthopaedic Surgery, Kanazawa University Graduate School of Medical Sciences, 13-1 Takara-machi, Kanazawa, 920-8641, Japan.

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http://dx.doi.org/10.1186/s12891-019-2453-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368706PMC
February 2019

A Novel Smoking Cessation Smartphone App Integrated With a Mobile Carbon Monoxide Checker for Smoking Cessation Treatment: Protocol for a Randomized Controlled Trial.

Authors:
Akihiro Nomura Hiroki Tateno Katsunori Masaki Tomoyasu Muto Shin Suzuki Kohta Satake Eisuke Hida Koichi Fukunaga

JMIR Res Protoc 2019 Feb 11;8(2):e12252. Epub 2019 Feb 11.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.2196/12252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388098PMC
February 2019

Impact of a Novel Smartphone App (CureApp Smoking Cessation) on Nicotine Dependence: Prospective Single-Arm Interventional Pilot Study.

Authors:
Katsunori Masaki Hiroki Tateno Naofumi Kameyama Eriko Morino Riri Watanabe Kazuma Sekine Tomohiro Ono Kohta Satake Shin Suzuki Akihiro Nomura Tomoko Betsuyaku Koichi Fukunaga

JMIR Mhealth Uhealth 2019 02 19;7(2):e12694. Epub 2019 Feb 19.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.2196/12694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399570PMC
February 2019

Functional analysis of KCNH2 gene mutations of type 2 long QT syndrome in larval zebrafish using microscopy and electrocardiography.

Authors:
Yoshihiro Tanaka Kenshi Hayashi Noboru Fujino Tetsuo Konno Hayato Tada Chiaki Nakanishi Akihiko Hodatsu Toyonobu Tsuda Yoji Nagata Ryota Teramoto Shohei Yoshida Akihiro Nomura Masa-Aki Kawashiri Masakazu Yamagishi

Heart Vessels 2019 Jan 25;34(1):159-166. Epub 2018 Jul 25.

Department of Cardiovascular and Internal Medicine, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8640, Japan.

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http://dx.doi.org/10.1007/s00380-018-1231-4DOI Listing
January 2019

Clinical whole exome sequencing in severe hypertriglyceridemia.

Authors:
Hayato Tada Akihiro Nomura Hirofumi Okada Takuya Nakahashi Tsuyoshi Nozue Kenshi Hayashi Atsushi Nohara Kunimasa Yagi Akihiro Inazu Ichiro Michishita Hiroshi Mabuchi Masakazu Yamagishi Masa-Aki Kawashiri

Clin Chim Acta 2019 Jan 30;488:31-39. Epub 2018 Oct 30.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S00098981183056
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http://dx.doi.org/10.1016/j.cca.2018.10.041DOI Listing
January 2019

DNA Sequence Variation in Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes.

Authors:
Connor A Emdin Amit V Khera Krishna Aragam Mary Haas Mark Chaffin Derek Klarin Pradeep Natarajan Alexander Bick Seyedeh M Zekavat Akihiro Nomura Diego Ardissino James G Wilson Heribert Schunkert Ruth McPherson Hugh Watkins Roberto Elosua Matthew J Bown Nilesh J Samani Usman Baber Jeanette Erdmann Namrata Gupta John Danesh Danish Saleheen Stacey Gabriel Sekar Kathiresan

Diabetes 2019 01 2;68(1):226-234. Epub 2018 Nov 2.

Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA

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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db18
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http://dx.doi.org/10.2337/db18-0857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302541PMC
January 2019

Post-prandial Remnant Lipoprotein Metabolism in Sitosterolemia.

Authors:
Hayato Tada Akihiro Nomura Atsushi Nohara Akihiro Inazu Hiroshi Mabuchi Masakazu Yamagishi Masa-Aki Kawashiri

J Atheroscler Thromb 2018 Dec 12;25(12):1188-1195. Epub 2018 Jul 12.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine.

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http://dx.doi.org/10.5551/jat.44768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249359PMC
December 2018

Impact of genetic testing on low-density lipoprotein cholesterol in patients with familial hypercholesterolemia (GenTLe-FH): a randomised waiting list controlled open-label study protocol.

Authors:
Akihiro Nomura Hayato Tada Hirofumi Okada Atsushi Nohara Hideki Ishikawa Kenichi Yoshimura Masa-Aki Kawashiri

BMJ Open 2018 12 28;8(12):e023636. Epub 2018 Dec 28.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.

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http://dx.doi.org/10.1136/bmjopen-2018-023636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318585PMC
December 2018

Serum triglycerides predict first cardiovascular events in diabetic patients with hypercholesterolemia and retinopathy.

Authors:
Hayato Tada Masa-Aki Kawashiri Akihiro Nomura Kenichi Yoshimura Hiroshi Itoh Issei Komuro Masakazu Yamagishi

Eur J Prev Cardiol 2018 11 30;25(17):1852-1860. Epub 2018 Aug 30.

1 Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Japan.

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http://dx.doi.org/10.1177/2047487318796989DOI Listing
November 2018

Ternary crystal structure of human RORĪ³ ligand-binding-domain, an inhibitor and corepressor peptide provides a new insight into corepressor interaction.

Authors:
Masato Noguchi Akihiro Nomura Satoki Doi Keishi Yamaguchi Kazuyuki Hirata Makoto Shiozaki Katsuya Maeda Shintaro Hirashima Masayuki Kotoku Takayuki Yamaguchi Yoshiaki Katsuda Paul Crowe Haiyan Tao Scott Thacher Tsuyoshi Adachi

Sci Rep 2018 11 26;8(1):17374. Epub 2018 Nov 26.

Pharmaceutical Frontier Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc., 1-13-2, Fukuura, Kanazawa-Ku, Yokohama, Kanagawa, 236-0004, Japan.

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http://www.nature.com/articles/s41598-018-35783-9
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http://dx.doi.org/10.1038/s41598-018-35783-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255837PMC
November 2018

Mendelian randomization: Its impact on cardiovascular disease.

Authors:
Masa-Aki Kawashiri Hayato Tada Akihiro Nomura Masakazu Yamagishi

J Cardiol 2018 10 22;72(4):307-313. Epub 2018 May 22.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.jjcc.2018.04.007DOI Listing
October 2018

Phenotype and Prognosis of the Lamin A/C Gene (LMNA) Mutation Carriers in Japan.

Authors:
Noboru Fujino Kenshi Hayashi Kenji Sakata Akihiro Nomura Masa-Aki Kawashiri

Circ J 2018 10 21;82(11):2699-2700. Epub 2018 Sep 21.

Department of Cardiovascular and Internal Medicine, Kanazawa University, Graduate School of Medical Science.

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http://dx.doi.org/10.1253/circj.CJ-18-0954DOI Listing
October 2018

Oral Fat Tolerance Test for Sitosterolemia and Familial Hypercholesterolemia: A Study Protocol.

Authors:
Akihiro Nomura Hayato Tada Atsushi Nohara Masa-Aki Kawashiri Masakazu Yamagishi

J Atheroscler Thromb 2018 Aug 20;25(8):741-746. Epub 2018 Jan 20.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine.

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http://dx.doi.org/10.5551/jat.42960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099073PMC
August 2018

Additive Prognostic Value of Carotid Plaque Score to Enhance the Age, Creatinine, and Ejection Fraction Score in Patients with Acute Coronary Syndrome.

Authors:
Takuya Nakahashi Hayato Tada Kenji Sakata Akihiro Nomura Miho Ohira Mika Mori Masayuki Takamura Kenshi Hayashi Masakazu Yamagishi Masa-Aki Kawashiri

J Atheroscler Thromb 2018 Aug 26;25(8):709-719. Epub 2018 Jan 26.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine.

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http://dx.doi.org/10.5551/jat.42317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099068PMC
August 2018

Paradoxical impact of decreased low-density lipoprotein cholesterol level at baseline on the long-term prognosis in patients with acute coronary syndrome.

Authors:
Takuya Nakahashi Hayato Tada Kenji Sakata Yohei Yakuta Yoshihiro Tanaka Akihiro Nomura Tadatsugu Gamou Hidenobu Terai Yuki Horita Masatoshi Ikeda Masanobu Namura Masayuki Takamura Kenshi Hayashi Masakazu Yamagishi Masa-Aki Kawashiri

Heart Vessels 2018 Jul 29;33(7):695-705. Epub 2017 Dec 29.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, 13-1, Takara-machi, Kanazawa, Ishikawa, 920-8640, Japan.

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http://dx.doi.org/10.1007/s00380-017-1111-3DOI Listing
July 2018

Acquired T790M Mutation After Relapse Following EGFR-TKI Therapy: A Population-based Multi-institutional Study.

Authors:
Takayuki Kaburagi Moriyuki Kiyoshima Takeshi Nawa Hideo Ichimura Takefumi Saito Kenji Hayashihara Hideyasu Yamada Hiroaki Satoh Takeo Endo Yoshihisa Inage Kazuhito Saito Masaharu Inagaki Nobuyuki Hizawa Yukio Sato Hiroichi Ishikawa Mitsuaki Sakai Koichi Kamiyama Norihiro Kikuchi Hiroyuki Nakamura Kinya Furukawa Takahide Kodama Takaaki Yamashita Akihiro Nomura Susumu Yoshida

Anticancer Res 2018 05;38(5):3145-3150

Divisions of Respiratory Medicine and Thoracic Surgery, Ibaraki Seinan Medical Center Hospital, Sakai-machi, Japan.

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http://dx.doi.org/10.21873/anticanres.12577DOI Listing
May 2018

Impact of B-Type Natriuretic Peptide Level on Risk Stratification of Thromboembolism and Death in Patients With Nonvalvular Atrial Fibrillation怀- The Hokuriku-Plus AF Registry.

Authors:
Kenshi Hayashi Toyonobu Tsuda Akihiro Nomura Noboru Fujino Atsushi Nohara Kenji Sakata Tetsuo Konno Chiaki Nakanishi Hayato Tada Yoji Nagata Ryota Teramoto Yoshihiro Tanaka Masa-Aki Kawashiri Masakazu Yamagishi

Circ J 2018 04 1;82(5):1271-1278. Epub 2018 Mar 1.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medical Science.

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https://www.jstage.jst.go.jp/article/circj/82/5/82_CJ-17-108
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http://dx.doi.org/10.1253/circj.CJ-17-1085DOI Listing
April 2018

Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease.

Authors:
Connor A Emdin Amit V Khera Mark Chaffin Derek Klarin Pradeep Natarajan Krishna Aragam Mary Haas Alexander Bick Seyedeh M Zekavat Akihiro Nomura Diego Ardissino James G Wilson Heribert Schunkert Ruth McPherson Hugh Watkins Roberto Elosua Matthew J Bown Nilesh J Samani Usman Baber Jeanette Erdmann Namrata Gupta John Danesh Daniel Chasman Paul Ridker Joshua Denny Lisa Bastarache Judith H Lichtman Gail D'Onofrio Jennifer Mattera John A Spertus Wayne H-H Sheu Kent D Taylor Bruce M Psaty Stephen S Rich Wendy Post Jerome I Rotter Yii-Der Ida Chen Harlan Krumholz Danish Saleheen Stacey Gabriel Sekar Kathiresan

Nat Commun 2018 04 24;9(1):1613. Epub 2018 Apr 24.

Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1038/s41467-018-03911-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915445PMC
April 2018

Late Gadolinium Enhancement for Prediction of Mutation-Positive Hypertrophic Cardiomyopathy on the Basis of Panel-Wide Sequencing.

Authors:
Ryota Teramoto Noboru Fujino Tetsuo Konno Akihiro Nomura Yoji Nagata Toyonobu Tsuda Hayato Tada Kenji Sakata Masakazu Yamagishi Kenshi Hayashi Masa-Aki Kawashiri

Circ J 2018 03 3;82(4):1139-1148. Epub 2018 Feb 3.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine.

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https://www.jstage.jst.go.jp/article/circj/82/4/82_CJ-17-101
Publisher Site
http://dx.doi.org/10.1253/circj.CJ-17-1012DOI Listing
March 2018

Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling.

Authors:
Connor A Emdin Amit V Khera Derek Klarin Pradeep Natarajan Seyedeh M Zekavat Akihiro Nomura Mary Haas Krishna Aragam Diego Ardissino James G Wilson Heribert Schunkert Ruth McPherson Hugh Watkins Roberto Elosua Matthew J Bown Nilesh J Samani Usman Baber Jeanette Erdmann Padhraig Gormley Aarno Palotie Nathan O Stitziel Namrata Gupta John Danesh Danish Saleheen Stacey Gabriel Sekar Kathiresan

Circulation 2018 01 5;137(3):222-232. Epub 2017 Oct 5.

Center for Genomic Medicine (C.A.E., A.V.K., D.K., P.N., S.M.Z., A.N., M.H., K.A., A.P., N.G., S.G., S.K.)

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.028021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771958PMC
January 2018

J Waves for Predicting Cardiac Events in Hypertrophic Cardiomyopathy.

Authors:
Toyonobu Tsuda Kenshi Hayashi Tetsuo Konno Kenji Sakata Takashi Fujita Akihiko Hodatsu Yoji Nagata Ryota Teramoto Akihiro Nomura Yoshihiro Tanaka Hiroshi Furusho Masayuki Takamura Masa-Aki Kawashiri Noboru Fujino Masakazu Yamagishi

JACC Clin Electrophysiol 2017 10 28;3(10):1136-1142. Epub 2017 Jun 28.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.jacep.2017.03.010DOI Listing
October 2017

Ternary complex of human RORĪ³ ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment.

Authors:
Masato Noguchi Akihiro Nomura Ken Murase Satoki Doi Keishi Yamaguchi Kazuyuki Hirata Makoto Shiozaki Shintaro Hirashima Masayuki Kotoku Takayuki Yamaguchi Yoshiaki Katsuda Ruo Steensma Xioalin Li Haiyan Tao Bruno Tse Morgan Fenn Robert Babine Erin Bradley Paul Crowe Scott Thacher Tsuyoshi Adachi Masafumi Kamada

Genes Cells 2017 Jun 11;22(6):535-551. Epub 2017 May 11.

Pharmaceutical Frontier Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc., 1-13-2, Fukuura, Kanazawa-Ku, Yokohama, Kanagawa, 236-0004, Japan.

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http://dx.doi.org/10.1111/gtc.12494DOI Listing
June 2017

Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease.

Authors:
Akihiro Nomura Hong-Hee Won Amit V Khera Fumihiko Takeuchi Kaoru Ito Shane McCarthy Connor A Emdin Derek Klarin Pradeep Natarajan Seyedeh M Zekavat Namrata Gupta Gina M Peloso Ingrid B Borecki Tanya M Teslovich Rosanna Asselta Stefano Duga Piera A Merlini Adolfo Correa Thorsten Kessler James G Wilson Matthew J Bown Alistair S Hall Peter S Braund David J Carey Michael F Murray H Lester Kirchner Joseph B Leader Daniel R Lavage J Neil Manus Dustin N Hartze Nilesh J Samani Heribert Schunkert Jaume Marrugat Roberto Elosua Ruth McPherson Martin Farrall Hugh Watkins Jyh-Ming J Juang Chao A Hsiung Shih-Yi Lin Jun-Sing Wang Hayato Tada Masa-Aki Kawashiri Akihiro Inazu Masakazu Yamagishi Tomohiro Katsuya Eitaro Nakashima Masahiro Nakatochi Ken Yamamoto Mitsuhiro Yokota Yukihide Momozawa Jerome I Rotter Eric S Lander Daniel J Rader John Danesh Diego Ardissino Stacey Gabriel Cristen J Willer Goncalo R Abecasis Danish Saleheen Michiaki Kubo Norihiro Kato Yii-Der Ida Chen Frederick E Dewey Sekar Kathiresan

Circ Res 2017 Jun 15;121(1):81-88. Epub 2017 May 15.

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http://dx.doi.org/10.1161/CIRCRESAHA.117.311145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523940PMC
June 2017

CNT Sheet Air Electrode for the Development of Ultra-High Cell Capacity in Lithium-Air Batteries.

Authors:
Akihiro Nomura Kimihiko Ito Yoshimi Kubo

Sci Rep 2017 04 5;7:45596. Epub 2017 Apr 5.

GREEN, National Institute for Materials Science, 1-1 Namiki, Tsukuba 305-0044, Japan.

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http://dx.doi.org/10.1038/srep45596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381228PMC
April 2017

ANGPTL3 Deficiency and Protection Against Coronary Artery Disease.

Authors:
Nathan O Stitziel Amit V Khera Xiao Wang Andrew J Bierhals A Christina Vourakis Alexandra E Sperry Pradeep Natarajan Derek Klarin Connor A Emdin Seyedeh M Zekavat Akihiro Nomura Jeanette Erdmann Heribert Schunkert Nilesh J Samani William E Kraus Svati H Shah Bing Yu Eric Boerwinkle Daniel J Rader Namrata Gupta Philippe M Frossard Asif Rasheed John Danesh Eric S Lander Stacey Gabriel Danish Saleheen Kiran Musunuru Sekar Kathiresan

J Am Coll Cardiol 2017 Apr 3;69(16):2054-2063. Epub 2017 Apr 3.

Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2017.02.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404817PMC
April 2017

Association of Rare and Common Variation in the Lipoprotein Lipase Gene With Coronary Artery Disease.

Authors:
Amit V Khera Hong-Hee Won Gina M Peloso Colm O'Dushlaine Dajiang Liu Nathan O Stitziel Pradeep Natarajan Akihiro Nomura Connor A Emdin Namrata Gupta Ingrid B Borecki Rosanna Asselta Stefano Duga Piera Angelica Merlini Adolfo Correa Thorsten Kessler James G Wilson Matthew J Bown Alistair S Hall Peter S Braund David J Carey Michael F Murray H Lester Kirchner Joseph B Leader Daniel R Lavage J Neil Manus Dustin N Hartzel Nilesh J Samani Heribert Schunkert Jaume Marrugat Roberto Elosua Ruth McPherson Martin Farrall Hugh Watkins Eric S Lander Daniel J Rader John Danesh Diego Ardissino Stacey Gabriel Cristen Willer GonƧalo R Abecasis Danish Saleheen Frederick E Dewey Sekar Kathiresan

JAMA 2017 03;317(9):937-946

Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts2Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston3Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston.

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http://dx.doi.org/10.1001/jama.2017.0972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664181PMC
March 2017

Mortality and predictors of appropriate implantable cardioverter defibrillator therapy in Japanese patients with Multicenter Automatic Defibrillator Implantation Trial II criteria.

Authors:
Yoshimori An Kenji Ando Yoshimitsu Soga Akihiro Nomura Michio Nagashima Kentaro Hayashi Yu Makihara Masato Fukunaga Ken-Ichi Hiroshima Masakiyo Nobuyoshi Masahiko Goya

J Arrhythm 2017 Feb 28;33(1):17-22. Epub 2016 Jun 28.

Department of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan.

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http://dx.doi.org/10.1016/j.joa.2016.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300836PMC
February 2017

Atypical Carcinoid Tumor with Anaplastic Lymphoma Kinase (ALK) Rearrangement Successfully Treated by an ALK Inhibitor.

Authors:
Masayuki Nakajima Naoki Uchiyama Rie Shigemasa Takeshi Matsumura Ryota Matsuoka Akihiro Nomura

Intern Med 2016;55(21):3151-3153. Epub 2016 Nov 1.

Department of Respiratory Medicine, Ibaraki Seinan Medical Center Hospital, Japan.

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http://dx.doi.org/10.2169/internalmedicine.55.6738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140865PMC
January 2017

Phenotypic Characterization of GeneticallyĀ Lowered Human Lipoprotein(a) Levels.

Authors:
Connor A Emdin Amit V Khera Pradeep Natarajan Derek Klarin Hong-Hee Won Gina M Peloso Nathan O Stitziel Akihiro Nomura Seyedeh M Zekavat Alexander G Bick Namrata Gupta Rosanna Asselta Stefano Duga Piera Angelica Merlini Adolfo Correa Thorsten Kessler James G Wilson Matthew J Bown Alistair S Hall Peter S Braund Nilesh J Samani Heribert Schunkert Jaume Marrugat Roberto Elosua Ruth McPherson Martin Farrall Hugh Watkins Cristen Willer GonƧalo R Abecasis Janine F Felix Ramachandran S Vasan Eric Lander Daniel J Rader John Danesh Diego Ardissino Stacey Gabriel Danish Saleheen Sekar Kathiresan

J Am Coll Cardiol 2016 Dec;68(25):2761-2772

Center for Human Genetic Research, Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2016.10.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328146PMC
December 2016

Impact of Baseline Angiographic Complexities Determined by Coronary Artery Bypass Grafting SYNTAX Score on the Prediction of Outcome After Percutaneous Coronary Intervention.

Authors:
Takuya Nakahashi Kenji Sakata Akihiro Nomura Yohei Yakuta Tadatsugu Gamou Hidenobu Terai Yuki Horita Masatoshi Ikeda Masanobu Namura Masayuki Takamura Masa-Aki Kawashiri Masakazu Yamagishi Kenshi Hayashi

Am J Cardiol 2016 10 18;118(7):974-9. Epub 2016 Jul 18.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.amjcard.2016.07.009DOI Listing
October 2016

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.

Authors:
Nathalie Chami Ming-Huei Chen Andrew J Slater John D Eicher Evangelos Evangelou Salman M Tajuddin Latisha Love-Gregory Tim Kacprowski Ursula M Schick Akihiro Nomura Ayush Giri Samuel Lessard Jennifer A Brody Claudia Schurmann Nathan Pankratz Lisa R Yanek Ani Manichaikul Raha Pazoki Evelin Mihailov W David Hill Laura M Raffield Amber Burt Traci M Bartz Diane M Becker Lewis C Becker Eric Boerwinkle Jette Bork-Jensen Erwin P Bottinger Michelle L O'Donoghue David R Crosslin Simon de Denus Marie-Pierre DubƩ Paul Elliott Gunnar Engstrƶm Michele K Evans James S Floyd Myriam Fornage He Gao Andreas Greinacher Vilmundur Gudnason Torben Hansen Tamara B Harris Caroline Hayward Jussi Hernesniemi Heather M Highland Joel N Hirschhorn Albert Hofman Marguerite R Irvin Mika KƤhƶnen Ethan Lange Lenore J Launer Terho LehtimƤki Jin Li David C M Liewald Allan Linneberg Yongmei Liu Yingchang Lu Leo-Pekka LyytikƤinen Reedik MƤgi Rasika A Mathias Olle Melander Andres Metspalu Nina Mononen Mike A Nalls Deborah A Nickerson Kjell Nikus Chris J O'Donnell Marju Orho-Melander Oluf Pedersen Astrid Petersmann Linda Polfus Bruce M Psaty Olli T Raitakari Emma Raitoharju Melissa Richard Kenneth M Rice Fernando Rivadeneira Jerome I Rotter Frank Schmidt Albert Vernon Smith John M Starr Kent D Taylor Alexander Teumer Betina H Thuesen Eric S Torstenson Russell P Tracy Ioanna Tzoulaki Neil A Zakai Caterina Vacchi-Suzzi Cornelia M van Duijn Frank J A van Rooij Mary Cushman Ian J Deary Digna R Velez Edwards Anne-Claire Vergnaud Lars Wallentin Dawn M Waterworth Harvey D White James G Wilson Alan B Zonderman Sekar Kathiresan Niels Grarup TƵnu Esko Ruth J F Loos Leslie A Lange Nauder Faraday Nada A Abumrad Todd L Edwards Santhi K Ganesh Paul L Auer Andrew D Johnson Alexander P Reiner Guillaume Lettre

Am J Hum Genet 2016 Jul 23;99(1):8-21. Epub 2016 Jun 23.

Department of Medicine, UniversitƩ de MontrƩal, MontrƩal, QC H3T 1J4, Canada; Montreal Heart Institute, MontrƩal, QC H1T 1C8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005438PMC
July 2016

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals.

Authors:
John D Eicher Nathalie Chami Tim Kacprowski Akihiro Nomura Ming-Huei Chen Lisa R Yanek Salman M Tajuddin Ursula M Schick Andrew J Slater Nathan Pankratz Linda Polfus Claudia Schurmann Ayush Giri Jennifer A Brody Leslie A Lange Ani Manichaikul W David Hill Raha Pazoki Paul Elliot Evangelos Evangelou Ioanna Tzoulaki He Gao Anne-Claire Vergnaud Rasika A Mathias Diane M Becker Lewis C Becker Amber Burt David R Crosslin Leo-Pekka LyytikƤinen Kjell Nikus Jussi Hernesniemi Mika KƤhƶnen Emma Raitoharju Nina Mononen Olli T Raitakari Terho LehtimƤki Mary Cushman Neil A Zakai Deborah A Nickerson Laura M Raffield Rakale Quarells Cristen J Willer Gina M Peloso Goncalo R Abecasis Dajiang J Liu Panos Deloukas Nilesh J Samani Heribert Schunkert Jeanette Erdmann Myriam Fornage Melissa Richard Jean-Claude Tardif John D Rioux Marie-Pierre Dube Simon de Denus Yingchang Lu Erwin P Bottinger Ruth J F Loos Albert Vernon Smith Tamara B Harris Lenore J Launer Vilmundur Gudnason Digna R Velez Edwards Eric S Torstenson Yongmei Liu Russell P Tracy Jerome I Rotter Stephen S Rich Heather M Highland Eric Boerwinkle Jin Li Ethan Lange James G Wilson Evelin Mihailov Reedik MƤgi Joel Hirschhorn Andres Metspalu TƵnu Esko Caterina Vacchi-Suzzi Mike A Nalls Alan B Zonderman Michele K Evans Gunnar Engstrƶm Marju Orho-Melander Olle Melander Michelle L O'Donoghue Dawn M Waterworth Lars Wallentin Harvey D White James S Floyd Traci M Bartz Kenneth M Rice Bruce M Psaty J M Starr David C M Liewald Caroline Hayward Ian J Deary Andreas Greinacher Uwe Vƶlker Thomas Thiele Henry Vƶlzke Frank J A van Rooij AndrƩ G Uitterlinden Oscar H Franco Abbas Dehghan Todd L Edwards Santhi K Ganesh Sekar Kathiresan Nauder Faraday Paul L Auer Alex P Reiner Guillaume Lettre Andrew D Johnson

Am J Hum Genet 2016 Jul 23;99(1):40-55. Epub 2016 Jun 23.

Population Sciences Branch, National Heart Lung and Blood Institute, The Framingham Heart Study, Framingham, MA 01702, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005441PMC
July 2016

Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia.

Authors:
Amit V Khera Hong-Hee Won Gina M Peloso Kim S Lawson Traci M Bartz Xuan Deng Elisabeth M van Leeuwen Pradeep Natarajan Connor A Emdin Alexander G Bick Alanna C Morrison Jennifer A Brody Namrata Gupta Akihiro Nomura Thorsten Kessler Stefano Duga Joshua C Bis Cornelia M van Duijn L Adrienne Cupples Bruce Psaty Daniel J Rader John Danesh Heribert Schunkert Ruth McPherson Martin Farrall Hugh Watkins Eric Lander James G Wilson Adolfo Correa Eric Boerwinkle Piera Angelica Merlini Diego Ardissino Danish Saleheen Stacey Gabriel Sekar Kathiresan

J Am Coll Cardiol 2016 06 3;67(22):2578-89. Epub 2016 Apr 3.

Center for Human Genetic Research, Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2016.03.520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405769PMC
June 2016

Fragmented QRS predicts heart failure progression in patients with hypertrophic cardiomyopathy.

Authors:
Akihiro Nomura Tetsuo Konno Takashi Fujita Yoshihiro Tanaka Yoji Nagata Toyonobu Tsuda Akihiko Hodatsu Kenji Sakata Hiroyuki Nakamura Masa-Aki Kawashiri Noboru Fujino Masakazu Yamagishi Kenshi Hayashi

Circ J 2015 7;79(1):136-43. Epub 2014 Nov 7.

Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine.

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http://dx.doi.org/10.1253/circj.CJ-14-0822DOI Listing
February 2016

Whole exome sequencing combined with integrated variant annotation prediction identifies a causative myosin essential light chain variant in hypertrophic cardiomyopathy.

Authors:
Akihiro Nomura Hayato Tada Ryota Teramoto Tetsuo Konno Akihiko Hodatsu Hong-Hee Won Sekar Kathiresan Hidekazu Ino Noboru Fujino Masakazu Yamagishi Kenshi Hayashi

J Cardiol 2016 Feb 9;67(2):133-9. Epub 2015 Oct 9.

Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S09145087150028
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http://dx.doi.org/10.1016/j.jjcc.2015.09.003DOI Listing
February 2016

Usefulness of Electrocardiographic Voltage to Determine Myocardial Fibrosis in Hypertrophic Cardiomyopathy.

Authors:
Tetsuo Konno Yoji Nagata Ryota Teramoto Noboru Fujino Akihiro Nomura Hayato Tada Kenji Sakata Hiroshi Furusho Masayuki Takamura Hiroyuki Nakamura Masa-Aki Kawashiri Masakazu Yamagishi Kenshi Hayashi

Am J Cardiol 2016 Feb 19;117(3):443-9. Epub 2015 Nov 19.

Division of Cardiovascular Medicine, Graduate School of Medicine, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.amjcard.2015.11.015DOI Listing
February 2016

Electrocardiographic QRS Fragmentation as a Marker for Myocardial Fibrosis in Hypertrophic Cardiomyopathy.

Authors:
Tetsuo Konno Kenshi Hayashi Noboru Fujino Rie Oka Akihiro Nomura Yoji Nagata Akihiko Hodatsu Kenji Sakata Hiroshi Furusho Masayuki Takamura Hiroyuki Nakamura Masa-Aki Kawashiri Masakazu Yamagishi

J Cardiovasc Electrophysiol 2015 Oct 11;26(10):1081-7. Epub 2015 Aug 11.

Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.

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http://dx.doi.org/10.1111/jce.12742DOI Listing
October 2015

[FACTORS ASSOCIATED WITH THE PRESENCE OF ALLERGEN-SPECIFIC IgE RESPONSES IN ASTHMA PATIENTS WHO HAD NO IgE RESPONSES DETECTABLE BY MAST-26].

Authors:
Hiroaki Iijima Yoshiko Kaneko Hironori Masuko Hideyasu Yamada Yohei Yatagai Tohru Sakamoto Koji Kanemoto Hiroichi Ishikawa Takefumi Saito Takeo Endo Hiroki Ninomiya Akihiro Nomura Takahide Kodama Norihiro Kaneko Fumio Kokubu Hironi Makita Satoshi Konno Masaharu Nishimura Nobuyuki Hizawa

Arerugi 2015 Sep;64(9):1242-53

Department of Respiratory Medicine, Tsukuba Medical Center Hospital.

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http://dx.doi.org/10.15036/arerugi.64.1242DOI Listing
September 2015

Can next-generation sequencing replace sanger sequencing for screening genetic variants?

Authors:
Masa-aki Kawashiri Akihiro Nomura Tetsuo Konno Kenshi Hayashi

Circ J 2014 4;78(12):2845-7. Epub 2014 Nov 4.

Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine.

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http://dx.doi.org/10.1253/circj.cj-14-1144DOI Listing
July 2015

Successful endovascular treatment for high take off aorto-iliac occlusive disease.

Authors:
Akihiro Nomura Michio Nagashima Yusuke Tomoi Atsushi Tosaka Yoshimitsu Soga

Intern Med 2015 15;54(8):921-4. Epub 2015 Apr 15.

Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Japan.

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http://dx.doi.org/10.2169/internalmedicine.54.2920DOI Listing
July 2015

Whole exome sequencing combined with integrated variant annotation prediction identifies asymptomatic Tangier disease with compound heterozygous mutations in ABCA1 gene.

Authors:
Hayato Tada Masa-Aki Kawashiri Atsushi Nohara Reina Saito Yoshihiro Tanaka Akihiro Nomura Tetsuo Konno Kenji Sakata Noboru Fujino Toshinari Takamura Akihiro Inazu Hiroshi Mabuchi Masakazu Yamagishi Kenshi Hayashi

Atherosclerosis 2015 Jun 7;240(2):324-9. Epub 2015 Apr 7.

Division of Cardiovascular Medicine, Kanazawa University, Graduate School of Medicine, Kanazawa, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S00219150150022
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http://dx.doi.org/10.1016/j.atherosclerosis.2015.04.003DOI Listing
June 2015

Right ventricular hypertrophy is associated with cardiovascular events in hypertrophic cardiomyopathy: evidence from study with magnetic resonance imaging.

Authors:
Yoji Nagata Tetsuo Konno Noboru Fujino Akihiko Hodatsu Akihiro Nomura Kenshi Hayashi Hiroyuki Nakamura Masa-Aki Kawashiri Masakazu Yamagishi

Can J Cardiol 2015 Jun 24;31(6):702-8. Epub 2015 Jan 24.

Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan; Research and Education Center for Innovative and Preventive Medicine, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.cjca.2014.12.036DOI Listing
June 2015

Impact of clinical and echocardiographic characteristics on occurrence of cardiac events in cardiac amyloidosis as proven by endomyocardial biopsy.

Authors:
Takuya Nakahashi Takeshi Arita Kyohei Yamaji Katsumi Inoue Tadaaki Yokota Yoshinobu Hoshii Masato Fukunaga Akihiro Nomura Hirotoshi Watanabe Shirou Miura Akihiro Isotani Yoshimitsu Soga Kenji Ando Masashi Iwabuchi Hiroyoshi Yokoi Hideyuki Nosaka Masakazu Yamagishi Masakiyo Nobuyoshi

Int J Cardiol 2014 Oct 2;176(3):753-9. Epub 2014 Aug 2.

Division of Cardiology, Kokura Memorial Hospital, Kitakyusyu, Japan.

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http://dx.doi.org/10.1016/j.ijcard.2014.07.100DOI Listing
October 2014

Enhanced formaldehyde-vapor adsorption capacity of polymeric amine-incorporated aminosilicas.

Authors:
Akihiro Nomura Christopher W Jones

Chemistry 2014 May 3;20(21):6381-90. Epub 2014 Apr 3.

School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Drive, Atlanta, GA 30332-0100 (USA), Fax: (+1)ā€‰404-894-2866.

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http://dx.doi.org/10.1002/chem.201304954DOI Listing
May 2014

Erlotinib for elderly patients with non-small-cell lung cancer: Subset analysis from a population-based observational study by the Ibaraki Thoracic Integrative (POSITIVE) Research Group.

Authors:
Koichi Kurishima Hiroaki Satoh Takayuki Kaburagi Yoshihiro Nishimura Yoko Shinohara Masaharu Inagaki Takeo Endo Takefumi Saito Kenji Hayashihara Nobuyuki Hizawa Hiroyuki Nakamura Takeshi Nawa Katsunori Kagohashi Koji Kishi Hiroichi Ishikawa Hideo Ichimura Toshio Hashimoto Yukio Sato Mitsuaki Sakai Koichi Kamiyama Takeshi Matsumura Koji Unoura Toshihiko Fukuoka Keiko Uchiumi Akihiro Nomura Kinya Furukawa

Mol Clin Oncol 2013 Sep 23;1(5):828-832. Epub 2013 Jul 23.

Tokyo Medical University, Ibaraki Medical Center Hospital, Ami, Ibaraki 300-0395, Japan.

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http://dx.doi.org/10.3892/mco.2013.154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915644PMC
September 2013

Amine-functionalized porous silicas as adsorbents for aldehyde abatement.

Authors:
Akihiro Nomura Christopher W Jones

ACS Appl Mater Interfaces 2013 Jun 7;5(12):5569-77. Epub 2013 Jun 7.

School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Drive, Atlanta, Georgia 30332-0100, USA.

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http://pubs.acs.org/doi/10.1021/am400810s
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June 2013

Impact of post-challenge hyperglycemia on clinical outcomes in Japanese patients with stable angina undergoing percutaneous coronary intervention.

Authors:
Shoichi Kuramitsu Hiroyoshi Yokoi Takenori Domei Akihiro Nomura Hirotoshi Watanabe Kyohei Yamaji Yoshimitsu Soga Takeshi Arita Katsuhiro Kondo Shinichi Shirai Kenji Ando Koyu Sakai Masashi Iwabuchi Hedeyuki Nosaka Masakiyo Nobuyoshi

Cardiovasc Diabetol 2013 May 7;12:74. Epub 2013 May 7.

Department of Cardiology, Kokura Memorial Hospital, 3-2-1 Asano, Kokurakita-ku, Kitakyushu 802-8555, Japan.

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http://dx.doi.org/10.1186/1475-2840-12-74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651729PMC
May 2013

Coexistence of visceral fat and multiple risk factor accumulations is strongly associated with coronary artery disease in Japanese (the VACATION-J study).

Authors:
Aki Hiuge-Shimizu Ken Kishida Tohru Funahashi Masaaki Okutsu Ryosuke Kametani Hiroshi Kobayashi Yoichi Nozaki Akihiro Nomura Hiroyoshi Yokoi Tohru Yoshizumi Tetsuya Ohira Tadashi Nakamura Yuji Matsuzawa Satoru Sumitsuji Iichiro Shimomura

J Atheroscler Thromb 2012 4;19(7):657-63. Epub 2012 May 4.

Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.

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http://dx.doi.org/10.5551/jat.13037DOI Listing
January 2013

Very long-term outcomes after percutaneous coronary intervention with bare metal stents for unprotected left main coronary artery disease.

Authors:
Akihiro Nomura Kyohei Yamaji Shinichi Shirai Fumio Omata Yoshimitsu Soga Michio Nagashima Takeshi Arita Kenji Ando Koyu Sakai Masahiko Goya Hiroyoshi Yokoi Masashi Iwabuchi Masakiyo Nobuyoshi

EuroIntervention 2012 Dec;8(8):962-9

Division of Cardiology, Kokura Memorial Hospital, 3-2-1 Asano, Kokurakita-ku, Kitakyushu, Fukuoka. Japan.

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http://www.pcronline.com/eurointervention/55th_issue/146
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http://dx.doi.org/10.4244/EIJV8I8A146DOI Listing
December 2012

Synthesis and characterization of polystyrene brushes for organic thin film transistors.

Authors:
Do-Hoon Hwang Akihiro Nomura Jeongsik Kim Ji-Hoon Kim Hyunduck Cho Changhee Lee Kohji Ohno Yoshinobu Tsujii

J Nanosci Nanotechnol 2012 May;12(5):4137-41

Department of Chemistry, and Chemistry Institute for Functional Materials, Pusan National University, Busan 609-735, Republic of Korea.

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http://dx.doi.org/10.1166/jnn.2012.5930DOI Listing
May 2012

Overexpression of GATA-3 protects against the development of hypersensitivity pneumonitis.

Authors:
Yosuke Matsuno Yukio Ishii Keigyou Yoh Yuko Morishima Norihiro Haraguchi Norihiro Kikuchi Takashi Iizuka Takumi Kiwamoto Shinsuke Homma Akihiro Nomura Tohru Sakamoto Morio Ohtsuka Nobuyuki Hizawa Satoru Takahashi

Am J Respir Crit Care Med 2007 Nov 23;176(10):1015-25. Epub 2007 Aug 23.

Department of Respiratory Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1164/rccm.200612-1887OCDOI Listing
November 2007

[Study on sleep apnea syndrome from view of various fields of medicine].

Authors:
Hiroshi Bando Yoshiyuki Miyamoto Akihiro Nomura Hiroyoshi Sei Keisuke Nishigawa Ikuji Kawata Toru Yokoi

Nihon Naika Gakkai Zasshi 2007 Nov;96(11):2564-73

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http://dx.doi.org/10.2169/naika.96.2564DOI Listing
November 2007

The effect of smoking-related hyperhomocysteinemia on spirometric declines in chronic obstructive pulmonary disease in elderly Japanese.

Authors:
Sachiko Kai Akihiro Nomura Yuko Morishima Yukio Ishii Tohru Sakamoto Ahmed E Hegab Kiyohisa Sekizawa

Arch Gerontol Geriatr 2006 Mar-Apr;42(2):117-24. Epub 2005 Aug 26.

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.

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http://dx.doi.org/10.1016/j.archger.2005.06.003DOI Listing
April 2007

Effect of inhaled steroids on increased collagen synthesis in asthma.

Authors:
Sachiko Kai Akihiro Nomura Yuko Morishima Yukio Ishii Tohru Sakamoto Takumi Kiwamoto Takashi Iizuka Kiyohisa Sekizawa

Respiration 2007 6;74(2):154-8. Epub 2006 Feb 6.

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.

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http://www.karger.com/doi/10.1159/000091390
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April 2007

Niflumic acid and AG-1478 reduce cigarette smoke-induced mucin synthesis: the role of hCLCA1.

Authors:
Ahmed E Hegab Tohru Sakamoto Akihiro Nomura Yukio Ishii Yuko Morishima Takashi Iizuka Takumi Kiwamoto Yosuke Matsuno Shinsuke Homma Kiyohisa Sekizawa

Chest 2007 Apr;131(4):1149-56

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan.

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http://dx.doi.org/10.1378/chest.06-2031DOI Listing
April 2007

Sleep stage determines the expression pattern of sleep apneas.

Authors:
Yuko Morishima Yukio Ishii Akihiro Nomura Hiroaki Satoh Tohru Sakamoto Toshiaki Homma Morio Ohtsuka

Intern Med 2007 1;46(1):45-8. Epub 2007 Jan 1.

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba.

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http://dx.doi.org/10.2169/internalmedicine.45.6014DOI Listing
January 2007

Anaerobic bacterial empyema accompanying intrathoracic gas formation in anorexia nervosa.

Authors:
Norihiro Kikuchi Akihiro Nomura Takeo Endo Kiyohisa Sekizawa

Int J Eat Disord 2006 Nov;39(7):621-3

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Japan.

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http://dx.doi.org/10.1002/eat.20275DOI Listing
November 2006

Association of phosphodiesterase 4D gene polymorphisms with chronic obstructive pulmonary disease: relationship to interleukin 13 gene polymorphism.

Authors:
Shinsuke Homma Tohru Sakamoto Ahmed E Hegab Wataru Saitoh Akihiro Nomura Yukio Ishii Yuko Morishima Takashi Iizuka Takumi Kiwamoto Yosuke Matsuno Hosam H Massoud Hosny M Massoud Khalid M Hassanein Kiyohisa Sekizawa

Int J Mol Med 2006 Nov;18(5):933-9

Department of Pulmonary Medicine, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences and University Hospital, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.

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November 2006

Transcription factors T-bet and GATA-3 regulate development of airway remodeling.

Authors:
Takumi Kiwamoto Yukio Ishii Yuko Morishima Keigyou Yoh Atsuko Maeda Kazusa Ishizaki Takashi Iizuka Ahmed E Hegab Yosuke Matsuno Shinsuke Homma Akihiro Nomura Tohru Sakamoto Satoru Takahashi Kiyohisa Sekizawa

Am J Respir Crit Care Med 2006 Jul 13;174(2):142-51. Epub 2006 Apr 13.

Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305, Japan.

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http://dx.doi.org/10.1164/rccm.200601-079OCDOI Listing
July 2006

Overexpression of the transcription factor GATA-3 enhances the development of pulmonary fibrosis.

Authors:
Toru Kimura Yukio Ishii Keigyou Yoh Yuko Morishima Takashi Iizuka Takumi Kiwamoto Yosuke Matsuno Shinsuke Homma Akihiro Nomura Tohru Sakamoto Satoru Takahashi Kiyohisa Sekizawa

Am J Pathol 2006 Jul;169(1):96-104

Department of Respiratory Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698754PMC
http://dx.doi.org/10.2353/ajpath.2006.051160DOI Listing
July 2006

MMP14 gene polymorphisms in chronic obstructive pulmonary disease.

Authors:
Wataru Saitoh Tohru Sakamoto Ahmed E Hegab Akihiro Nomura Yukio Ishii Yuko Morishima Sachiko Kai Takashi Iizuka Takumi Kiwamoto Yosuke Matsuno Hosam H Massoud Hosny M Massoud Khalid M Hassanein Kiyohisa Sekizawa

Int J Mol Med 2006 Apr;17(4):621-6

Department of Pulmonary Medicine, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences and University Hospital, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.

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April 2006

Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema.

Authors:
Takashi Iizuka Yukio Ishii Ken Itoh Takumi Kiwamoto Toru Kimura Yosuke Matsuno Yuko Morishima Ahmed E Hegab Shinsuke Homma Akihiro Nomura Tohru Sakamoto Masako Shimura Aruto Yoshida Masayuki Yamamoto Kiyohisa Sekizawa

Genes Cells 2005 Dec;10(12):1113-25

Department of Respiratory Medicine, University of Tsukuba, Japan.

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http://doi.wiley.com/10.1111/j.1365-2443.2005.00905.x
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http://dx.doi.org/10.1111/j.1365-2443.2005.00905.xDOI Listing
December 2005

Transcription factor Nrf2 plays a pivotal role in protection against elastase-induced pulmonary inflammation and emphysema.

Authors:
Yukio Ishii Ken Itoh Yuko Morishima Toru Kimura Takumi Kiwamoto Takashi Iizuka Ahmed E Hegab Tomonori Hosoya Akihiro Nomura Tohru Sakamoto Masayuki Yamamoto Kiyohisa Sekizawa

J Immunol 2005 Nov;175(10):6968-75

Department of Respiratory Medicine, University of Tsukuba, Japan.

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http://dx.doi.org/10.4049/jimmunol.175.10.6968DOI Listing
November 2005

Suppression of eosinophilic airway inflammation by treatment with alpha-galactosylceramide.

Authors:
Yuko Morishima Yukio Ishii Toru Kimura Akira Shibuya Kazuko Shibuya Ahmed E Hegab Takashi Iizuka Takumi Kiwamoto Yosuke Matsuno Tohru Sakamoto Akihiro Nomura Masaru Taniguchi Kiyohisa Sekizawa

Eur J Immunol 2005 Oct;35(10):2803-14

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Japan.

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http://dx.doi.org/10.1002/eji.200525994DOI Listing
October 2005

Role of 15-deoxy delta(12,14) prostaglandin J2 and Nrf2 pathways in protection against acute lung injury.

Authors:
Mie Mochizuki Yukio Ishii Ken Itoh Takashi Iizuka Yuko Morishima Toru Kimura Takumi Kiwamoto Yosuke Matsuno Ahamed E Hegab Akihiro Nomura Tohru Sakamoto Koji Uchida Masayuki Yamamoto Kiyohisa Sekizawa

Am J Respir Crit Care Med 2005 Jun 4;171(11):1260-6. Epub 2005 Mar 4.

Department of Respiratory Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305, Japan.

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http://dx.doi.org/10.1164/rccm.200406-755OCDOI Listing
June 2005

Polymorphisms of TNFalpha, IL1beta, and IL1RN genes in chronic obstructive pulmonary disease.

Authors:
Ahmed E Hegab Tohru Sakamoto Wataru Saitoh Akihiro Nomura Yukio Ishii Yuko Morishima Takashi Iizuka Takumi Kiwamoto Yosuke Matsuno Hosam H Massoud Hosny M Massoud Khalid M Hassanein Kiyohisa Sekizawa

Biochem Biophys Res Commun 2005 Apr;329(4):1246-52

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0500356
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http://dx.doi.org/10.1016/j.bbrc.2005.02.099DOI Listing
April 2005

Promoter activity of human tissue inhibitor of metalloproteinase 2 gene with novel single nucleotide polymorphisms.

Authors:
Ahmed E Hegab Tohru Sakamoto Yoshiyuki Uchida Akihiro Nomura Yukio Ishii Yuko Morishima Mie Mochizuki Toru Kimura Wataru Saitoh Takashi Iizuka Takumi Kiwamoto Kiyohisa Sekizawa

Respirology 2005 Jan;10(1):27-30

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1111/j.1440-1843.2005.00654.xDOI Listing
January 2005

Cysteinyl leukotrienes and collagen type I synthesis in asthma.

Authors:
Akihiro Nomura Takahide Kodama Yuko Morishima Yukio Ishii Tohru Sakamoto Toru Kimura Kiyohisa Sekizawa

J Allergy Clin Immunol 2004 Jul;114(1):197-9

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http://dx.doi.org/10.1016/j.jaci.2004.03.037DOI Listing
July 2004

Treatment with alpha-galactosylceramide attenuates the development of bleomycin-induced pulmonary fibrosis.

Authors:
Toru Kimura Yukio Ishii Yuko Morishima Akira Shibuya Kazuko Shibuya Masaru Taniguchi Mie Mochizuki Ahmed E Hegab Tohru Sakamoto Akihiro Nomura Kiyohisa Sekizawa

J Immunol 2004 May;172(9):5782-9

Department of Respiratory Medicine, University of Tsukuba, Tennoudai, Tsukuba, Japan.

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http://dx.doi.org/10.4049/jimmunol.172.9.5782DOI Listing
May 2004

Sputum E-cadherin and asthma severity.

Authors:
Kuniko Masuyama Yuko Morishima Yukio Ishii Akihiro Nomura Tohru Sakamoto Toru Kimura Mie Mochizuki Yoshiyuki Uchida Kiyohisa Sekizawa

J Allergy Clin Immunol 2003 Jul;112(1):208-9

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http://dx.doi.org/10.1067/mai.2003.1526DOI Listing
July 2003

Anti-inflammatory activity of creatine supplementation in endothelial cells in vitro.

Authors:
Akihiro Nomura Minjie Zhang Tohru Sakamoto Yukio Ishii Yuko Morishima Mie Mochizuki Toru Kimura Yoshiyuki Uchida Kiyohisa Sekizawa

Br J Pharmacol 2003 Jun;139(4):715-20

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, Tennoudai 1-1-1, Tsukuba, Ibaraki 305-8575, Japan.

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http://dx.doi.org/10.1038/sj.bjp.0705316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573908PMC
June 2003

Age-related changes in plasma orexin-A concentrations.

Authors:
Takeshi Matsumura Mika Nakayama Akihiro Nomura Asuka Naito Kazuyuki Kamahara Kennosuke Kadono Masaaki Inoue Toshiaki Homma Kiyohisa Sekizawa

Exp Gerontol 2002 Aug-Sep;37(8-9):1127-30

Department of Respiratory Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennoudai Tsukuba, Ibaraki 305-8575, Japan.

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http://dx.doi.org/10.1016/s0531-5565(02)00092-xDOI Listing
October 2002

S-carboxymethylcysteine inhibits neutrophil activation mediated by N-formyl-methionyl-leucyl-phenylalanine.

Authors:
Yukio Ishii Toru Kimura Yuko Morishima Mie Mochizuki Akihiro Nomura Tohru Sakamoto Yoshiyuki Uchida Kiyohisa Sekizawa

Eur J Pharmacol 2002 Aug;449(1-2):183-9

Department of Respiratory Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Ten-nohdai, Tsukuba, Ibaraki 305-0006, Japan.

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http://dx.doi.org/10.1016/s0014-2999(02)01981-7DOI Listing
August 2002

Ebselen suppresses late airway responses and airway inflammation in guinea pigs.

Authors:
Minjie Zhang Akihiro Nomura Yoshiyuki Uchida Hiroaki Iijima Tohru Sakamoto Yukio Iishii Yuko Morishima Mie Mochizuki Kuniko Masuyama Kuniyoshi Hirano Kiyohisa Sekizawa

Free Radic Biol Med 2002 Mar;32(5):454-64

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, Tennoudai 1-1-1, Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1016/s0891-5849(01)00825-5DOI Listing
March 2002

Involvement of thromboxane A(2) in airway mucous cells in asthma-related cough.

Authors:
Anbo Xiang Yoshiyuki Uchida Akihiro Nomura Hiroaki Iijima Tohru Sakamoto Yukio Ishii Yuko Morishima Kuniko Masuyama Minjie Zhang Kuniyoshi Hirano Kiyohisa Sekizawa

J Appl Physiol (1985) 2002 Feb;92(2):763-70

Department of Pulmonary Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.

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http://dx.doi.org/10.1152/jappl.2002.92.2.763DOI Listing
February 2002