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Ake T Lu | PubFacts

Publications by authors named "Ake T Lu"

28Publications

Epigenetic mutation load is weakly correlated with epigenetic age acceleration.

Aging (Albany NY) 2020 Sep 29;12(18):17863-17894. Epub 2020 Sep 29.

Department of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA 90095, USA.

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September 2020

Rapamycin retards epigenetic ageing of keratinocytes independently of its effects on replicative senescence, proliferation and differentiation.

Aging (Albany NY) 2019 05;11(10):3238-3249

Radiation Effects Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Chilton, Didcot, Oxfordshire OX11 0RQ, United Kingdom.

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May 2019

Longitudinal Epigenome-Wide Methylation Study of Cognitive Decline and Motor Progression in Parkinson's Disease.

J Parkinsons Dis 2019 ;9(2):389-400

Department of Epidemiology, Fielding School of Public Health (FSPH), University of California Los Angeles (UCLA), Los Angeles, CA, USA.

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April 2020

DNA methylation GrimAge strongly predicts lifespan and healthspan.

Aging (Albany NY) 2019 01;11(2):303-327

Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.

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January 2019

Genetic architecture of epigenetic and neuronal ageing rates in human brain regions.

Nat Commun 2017 05 18;8:15353. Epub 2017 May 18.

Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095, USA.

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May 2017

Menopause accelerates biological aging.

Proc Natl Acad Sci U S A 2016 08 25;113(33):9327-32. Epub 2016 Jul 25.

Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095; Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, CA 90095

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August 2016

Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum.

Nat Commun 2016 Feb 2;7:10561. Epub 2016 Feb 2.

Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095, USA.

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February 2016

Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer's disease related cognitive functioning.

Aging (Albany NY) 2015 Dec;7(12):1198-211

Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.

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December 2015

The cerebellum ages slowly according to the epigenetic clock.

Aging (Albany NY) 2015 May;7(5):294-306

UCLA Molecular Biology Institute, Department of Chemistry and Biochemistry; Los Angeles, CA 90095, USA.

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May 2015

Identifying rare-variant associations in parent-child trios using a Gaussian support vector machine.

BMC Proc 2014 17;8(Suppl 1 Genetic Analysis Workshop 18Vanessa Olmo):S98. Epub 2014 Jun 17.

Department of Human Genetics, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90095, USA ; Center for Neurobehavioral Genetics, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90095, USA.

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December 2014

Keratoconus diagnosis with optical coherence tomography pachymetry mapping.

Ophthalmology 2008 Dec 5;115(12):2159-66. Epub 2008 Nov 5.

Center for Ophthalmic Optics and Lasers, Doheny Eye Institute and Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, California 99033, USA.

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December 2008

A 12-year follow-up study of psychiatric symptomatology among cocaine-dependent men.

Addict Behav 2006 Nov 28;31(11):1974-87. Epub 2006 Feb 28.

University of California, Los Angeles, Integrated Substance Abuse Programs, 1640 S. Sepulveda Blvd., Suite 200, Los Angeles, CA 90025, USA.

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November 2006