Publications by authors named "Ake Lernmark"

100Publications

Decreased HLA-DQ expression on peripheral blood cells in children with varying number of beta cell autoantibodies.

J Transl Autoimmun 2020 9;3:100052. Epub 2020 Apr 9.

Department of Clinical Sciences, Lund University/CRC, Skåne University Hospital, 205 02, Malmö, Sweden.

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April 2020

Immunocyte single cell analysis of vaccine-induced narcolepsy.

Eur J Immunol 2020 Jul 15. Epub 2020 Jul 15.

Department of Clinical Sciences, Lund University/Clinical Research Center (CRC), Skåne University Hospital SUS, Malmö, 21430, Sweden.

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July 2020

Periodontal conditions, retinopathy, and serum markers in individuals with type 1 diabetes.

J Periodontol 2020 Nov 1;91(11):1436-1443. Epub 2020 Jul 1.

Faculty of Health Sciences, Kristianstad University, Kristianstad, Sweden.

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November 2020

Screening for autoantibody targets in post-vaccination narcolepsy using proteome arrays.

Scand J Immunol 2020 Apr 13;91(4):e12864. Epub 2020 Feb 13.

Department of Medicine (Solna), Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.

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April 2020

Hyaluronan deposition in islets may precede and direct the location of islet immune-cell infiltrates.

Diabetologia 2020 03 6;63(3):549-560. Epub 2020 Jan 6.

Diabetes Research Program and Clinical Research Center, Benaroya Research Institute at Virginia Mason, Seattle, WA, USA.

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March 2020

HLA high-resolution typing by next-generation sequencing in Pandemrix-induced narcolepsy.

PLoS One 2019 2;14(10):e0222882. Epub 2019 Oct 2.

Department of Clinical Sciences Malmö, Lund University/CRC, Skåne University Hospital SUS, Malmö, Sweden.

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March 2020

Predicting Islet Cell Autoimmunity and Type 1 Diabetes: An 8-Year TEDDY Study Progress Report.

Diabetes Care 2019 06 9;42(6):1051-1060. Epub 2019 Apr 9.

Department of Clinical Sciences, Clinical Research Centre, Lund University, Skane University Hospital, Malmö, Sweden.

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June 2019

Genetic Variation Within the Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes.

Diabetes 2019 07 8;68(7):1523-1527. Epub 2019 Apr 8.

Division of Endocrinology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA

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July 2019

The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update.

Curr Diab Rep 2018 10 23;18(12):136. Epub 2018 Oct 23.

Health Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.

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October 2018

Reduction in White Blood Cell, Neutrophil, and Red Blood Cell Counts Related to Sex, HLA, and Islet Autoantibodies in Swedish TEDDY Children at Increased Risk for Type 1 Diabetes.

Diabetes 2018 11 13;67(11):2329-2336. Epub 2018 Aug 13.

Department of Clinical Sciences, Lund University/Clinical Research Centre, Skåne University Hospital, Malmö, Sweden.

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November 2018

First trimester enterovirus IgM and beta cell autoantibodies in mothers to children affected by type 1 diabetes autoimmunity before 7 years of age.

J Reprod Immunol 2018 06 2;127:1-6. Epub 2018 Mar 2.

Department of Clinical Sciences, Lund University Clinical Research Center, Skåne University Hospital, 205 02 Malmö, Sweden. Electronic address:

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June 2018

Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables.

Lancet Diabetes Endocrinol 2018 05 5;6(5):361-369. Epub 2018 Mar 5.

Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden; Finnish Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland. Electronic address:

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May 2018

Genetic risk scores in adult-onset type 1 diabetes.

Lancet Diabetes Endocrinol 2018 03;6(3):168-169

Diabetes and Celiac Unit, Lund University, Lund, Sweden.

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March 2018

Are Perinatal Events Risk Factors for Childhood Thyroid Autoimmunity?

Eur Thyroid J 2017 Nov 19;6(6):298-306. Epub 2017 Sep 19.

Department of Clinical Sciences, Malmö, Lund University, Skåne University Hospital, Malmö, Sweden.

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November 2017

HLA, infections and inflammation in early stages of atherosclerosis in children with type 1 diabetes.

Acta Diabetol 2018 Jan 24;55(1):41-47. Epub 2017 Oct 24.

Department of Paediatric Cardiology, Paediatric Heart Center, Lund University and Skåne University Hospital, 22185, Lund, Sweden.

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January 2018

Understanding and preventing type 1 diabetes through the unique working model of TrialNet.

Diabetologia 2017 Nov 2;60(11):2139-2147. Epub 2017 Aug 2.

Department of Immunobiology, Faculty of Life Sciences & Medicine, King's College London, London, SE1 9RT, UK.

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November 2017

Cesarean Section on the Risk of Celiac Disease in the Offspring: The Teddy Study.

J Pediatr Gastroenterol Nutr 2018 03;66(3):417-424

*Dr. v. Hauner Children's Hospital, University Munich Medical Center, Munich, Germany †Health Informatics Institute, Department of Paediatrics, Morsani College of Medicine, University of South Florida, Tampa, FL, USA ‡Institute of Diabetes Research, Helmholtz Zentrum München, Klinikum rechts der Isar, Technische Universität München, and Forschergruppe Diabetes e.V., Neuherberg, Germany §Department of Clinical Sciences, Lund University, Skane University Hosptial, Malmo, Sweden ||Digestive Health Institute, University of Colorado, Children's Hospital Colorado, Aurora, CO, USA ¶Medicity Laboratory, University of Turku, Turku, Finland #Tampere Centre for Child Health Research, University of Tampere and Tampere University Hospital, Tampere, Finland **Pacific Northwest Diabetes Research Institute, Seattle WA, USA ††Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora CO, USA ‡‡Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta University, Augusta GA, USA §§Department of Paediatrics, Turku University Hospital, Turku, Finland ||||Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland ¶¶Departments of Physiology, University of Turku, Turku, Finland.

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March 2018

Early prediction of autoimmune (type 1) diabetes.

Diabetologia 2017 08 26;60(8):1370-1381. Epub 2017 May 26.

Department of Clinical Sciences, Lund University/CRC, Skåne University Hospital, Jan Waldenströms gata 35, SE-20502, Malmö, Sweden.

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August 2017

Type 1 diabetes mellitus.

Nat Rev Dis Primers 2017 Mar 30;3:17016. Epub 2017 Mar 30.

Department of Clinical Sciences, Lund University, Skåne University Hospital, Jan Waldenströms gata 35, 20502 Malmö, Sweden.

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March 2017

Longitudinal analysis of hepatic transcriptome and serum metabolome demonstrates altered lipid metabolism following the onset of hyperglycemia in spontaneously diabetic biobreeding rats.

PLoS One 2017 13;12(2):e0171372. Epub 2017 Feb 13.

Diabetes and Celiac Disease Unit, Department of Clinical Sciences, Lund University/Clinical Research Centre and Skåne University Hospital, Malmö, Sweden.

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August 2017

Environmental factors in the etiology of type 1 diabetes, celiac disease, and narcolepsy.

Authors:
Åke Lernmark

Pediatr Diabetes 2016 07;17 Suppl 22:65-72

Department of Clinical Sciences, Lund University, Malmö, Sweden.

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July 2016

Reversion of β-Cell Autoimmunity Changes Risk of Type 1 Diabetes: TEDDY Study.

Diabetes Care 2016 Sep 16;39(9):1535-42. Epub 2016 Jun 16.

Health Informatics Institute, Department of Pediatrics, Morsani College of Medicine, University of South Florida, Tampa, FL.

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September 2016

Genetic risk factors for type 1 diabetes.

Lancet 2016 Jun;387(10035):2331-2339

Department of Clinical Sciences, Lund University, Skåne University Hospital, SE-20502 Malmö, Sweden. Electronic address:

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June 2016

An Object-Oriented Regression for Building Disease Predictive Models with Multiallelic HLA Genes.

Genet Epidemiol 2016 May;40(4):315-32

Department of Clinical Sciences, Lund University/CRC, Skåne University Hospital, Malmö, Sweden.

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May 2016

Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study.

JAMA Pediatr 2016 Jan;170(1):20-8

National Institute for Health and Welfare, Nutrition Unit, Helsinki, Finland12School of Health Sciences and Center for Child Health Research, University of Tampere and Tampere University Hospital, Tampere, Finland 13The Science Center of Pirkanmaa Hospita.

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January 2016

Diabetes at the crossroads: relevance of disease classification to pathophysiology and treatment.

Diabetologia 2016 Jan;59(1):13-20

Department of Clinical Sciences, Lund University/CRC, Malmö, Sweden.

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January 2016

Effects of Gluten Intake on Risk of Celiac Disease: A Case-Control Study on a Swedish Birth Cohort.

Clin Gastroenterol Hepatol 2016 Mar 25;14(3):403-409.e3. Epub 2015 Nov 25.

Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden. Electronic address:

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March 2016

Elevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person Syndrome.

Sci Rep 2015 Jun 16;5:11196. Epub 2015 Jun 16.

Dept. of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

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June 2015

Magnetic resonance imaging reveals altered distribution of hepatic fat in children with type 1 diabetes compared to controls.

Metabolism 2015 Aug 15;64(8):872-8. Epub 2015 Apr 15.

Paediatric Endocrinology, Diabetes and Celiac Disease Unit, Department of Clinical Sciences, Lund University/Clinical Research Centre and Skåne University Hospital, Malmö, Sweden.

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August 2015

Plasma GAD65, a Marker for Early β-Cell Loss After Intraportal Islet Cell Transplantation in Diabetic Patients.

J Clin Endocrinol Metab 2015 Jun 27;100(6):2314-21. Epub 2015 Mar 27.

Diabetes Research Center and Universitair Ziekenhuis Brussel (Z.L., P.D.P., D.J.-T.-T., R.M., G.A.M., P.I.V., B.K., F.G., D.P.), Brussels Free University-VUB, B-1090 Brussels, Belgium; Department of Endocrinology (P.G.), Universitair Ziekenhuis Gasthuisberg, Katholieke Universiteit Leuven-KUL, B-3000 Leuven, Belgium; Department of Medicine (C.S.H.), University of Washington, Seattle, Washington 98109; and Department of Clinical Sciences (Å.L.), Lund University, Skåne University Hospital, SE-20502 Malmö, Sweden.

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June 2015

The streetlight effect--is there light at the end of the tunnel?

Authors:
Åke Lernmark

Diabetes 2015 Apr;64(4):1105-7

Department of Clinical Sciences, Lund University/Clinical Research Centre, Skåne University Hospital, Malmö, Sweden

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April 2015

The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study.

Diabetologia 2015 May 10;58(5):980-7. Epub 2015 Feb 10.

Department of Pediatrics, Morsani College of Medicine, University of South Florida, 3650 Spectrum Boulevard, Suite 100, Tampa, FL, 33612, USA,

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May 2015

A functional polymorphism of Ptpn22 is associated with type 1 diabetes in the BioBreeding rat.

J Immunol 2015 Jan 12;194(2):615-29. Epub 2014 Dec 12.

Department of Immunology, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada; Biological Sciences Platform, Sunnybrook Research Institute, Toronto, Ontario M4N 3M5, Canada;

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January 2015

Baseline heterogeneity in glucose metabolism marks the risk for type 1 diabetes and complicates secondary prevention.

Acta Diabetol 2015 Jun 8;52(3):473-81. Epub 2014 Nov 8.

Department of Clinical Sciences Malmö/Pediatric Endocrinology, Skåne University Hospital SUS, Lund University, Jan Waldenströms gata 35, CRC 60:11, 20502, Malmö, Sweden,

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June 2015

Neuropeptide Y is a minor autoantigen in newly diagnosed type 1 diabetes patients.

Pediatr Diabetes 2015 Dec 25;16(8):621-8. Epub 2014 Sep 25.

Department of Clinical Sciences, Malmö, Lund University, Skåne University Hospital, SE-20502, Malmö, Sweden.

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December 2015