Publications by authors named "Ajjai Alva"

85Publications

Immunotherapy in metastatic sarcomatoid renal cell carcinoma: A single institution experience.

Cancer Treat Res Commun 2020 23;25:100251. Epub 2020 Nov 23.

Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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November 2020

Mismatch repair deficiency in metastatic prostate cancer: Response to PD-1 blockade and standard therapies.

PLoS One 2020 26;15(5):e0233260. Epub 2020 May 26.

Division of Oncology, Department of Medicine, University of Washington, Seattle, WA, United States of America.

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August 2020

A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies.

Oncotarget 2020 Apr 7;11(14):1235-1243. Epub 2020 Apr 7.

Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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April 2020

Reply by Authors.

J Urol 2020 04 22;203(4):697-698. Epub 2020 Jan 22.

Department of Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania.

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April 2020

Clinical Outcomes in Cyclin-dependent Kinase 12 Mutant Advanced Prostate Cancer.

Eur Urol 2020 03 20;77(3):333-341. Epub 2019 Oct 20.

Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.

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March 2020

Detection of CTC Clusters and a Dedifferentiated RNA-Expression Survival Signature in Prostate Cancer.

Adv Sci (Weinh) 2019 Jan 15;6(2):1801254. Epub 2018 Nov 15.

Department of Chemical Engineering University of Michigan 2300 Hayward Street Ann Arbor MI 48109 USA.

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January 2019

Phase II trial of palbociclib in patients with metastatic urothelial cancer after failure of first-line chemotherapy.

Br J Cancer 2018 10 8;119(7):801-807. Epub 2018 Oct 8.

Division of Hematology/Oncology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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October 2018

Frequent PD-L1 Protein Expression and Molecular Correlates in Urinary Bladder Squamous Cell Carcinoma.

Eur Urol 2018 10 3;74(4):529-531. Epub 2018 Jul 3.

Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA; Rogel Cancer Center, Michigan Medicine, Ann Arbor, MI, USA; Michigan Center for Translational Pathology, Ann Arbor, MI, USA. Electronic address:

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October 2018

Inactivation of CDK12 Delineates a Distinct Immunogenic Class of Advanced Prostate Cancer.

Cell 2018 06;173(7):1770-1782.e14

Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA; Department of Urology, University of Michigan, Ann Arbor, MI 48109, USA; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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June 2018

Ipilimumab induced digital vasculitis.

J Immunother Cancer 2018 02 12;6(1):12. Epub 2018 Feb 12.

Division of Hematology Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.

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February 2018

Bladder Cancer Treatment Response Assessment in CT using Radiomics with Deep-Learning.

Sci Rep 2017 08 18;7(1):8738. Epub 2017 Aug 18.

Department of Radiology, The University of Michigan, Ann Arbor, Michigan, 48109, United States.

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August 2017

Urinary bladder cancer staging in CT urography using machine learning.

Med Phys 2017 Nov 5;44(11):5814-5823. Epub 2017 Sep 5.

Department of Radiology, The University of Michigan, Ann Arbor, MI, 48109, USA.

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November 2017

Programmed Death-ligand 1 Expression in Upper Tract Urothelial Carcinoma.

Eur Urol Focus 2017 10 13;3(4-5):502-509. Epub 2016 Dec 13.

Department of Pathology, University of Michigan Health System, Ann Arbor, MI, USA; Comprehensive Cancer Center, University of Michigan Health System, Ann Arbor, MI, USA; Michigan Center for Translational Pathology, Ann Arbor, MI, USA. Electronic address:

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October 2017

Dorsal Muscle Attenuation May Predict Failure to Respond to Interleukin-2 Therapy in Metastatic Renal Cell Carcinoma.

Acad Radiol 2017 09 22;24(9):1094-1100. Epub 2017 Mar 22.

Department of Radiology, University of Michigan Health System, 1500 E. Medical Center Dr. B2-A209P, Ann Arbor, MI 48108; Department of Urology, University of Michigan Health System, Ann Arbor, Michigan; Michigan Radiology Quality Collaborative, Ann Arbor, Michigan. Electronic address:

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September 2017

Expression of PDL1 (B7-H1) Before and After Neoadjuvant Chemotherapy in Urothelial Carcinoma.

Eur Urol Focus 2016 Feb 6;1(3):265-268. Epub 2015 Jun 6.

Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA; Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA; Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address:

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February 2016

Urothelial Cancer With Occult Bone Marrow Metastases and Isolated Thrombocytopenia.

Urol Case Rep 2015 Jul 22;3(4):98-100. Epub 2015 Feb 22.

University of Michigan, Comprehensive Cancer Center, USA; Department of Pathology, University of Michigan, USA.

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July 2015

Genomic Profiling of Penile Squamous Cell Carcinoma Reveals New Opportunities for Targeted Therapy.

Cancer Res 2015 Dec;75(24):5219-27

Department of Pathology, Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan. Department of Urology, University of Michigan, Ann Arbor, Michigan. Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan.

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December 2015

Treatment Response Assessment for Bladder Cancer on CT Based on Computerized Volume Analysis, World Health Organization Criteria, and RECIST.

AJR Am J Roentgenol 2015 Aug;205(2):348-52

1 Department of Radiology, The University of Michigan, MIB C476, 1500 East Medical Center Dr, Ann Arbor, MI 48109-5842.

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August 2015

Circulating Tumor Cells as Potential Biomarkers in Bladder Cancer.

J Urol 2015 Sep 23;194(3):790-8. Epub 2015 Apr 23.

Department of Urology, Helen Diller Family Comprehensive Cancer Center, University of California-San Francisco, San Francisco, California.

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September 2015

SWOG S0925: A Randomized Phase II Study of Androgen Deprivation Combined With Cixutumumab Versus Androgen Deprivation Alone in Patients With New Metastatic Hormone-Sensitive Prostate Cancer.

J Clin Oncol 2015 May 6;33(14):1601-8. Epub 2015 Apr 6.

Evan Y. Yu, Hongli Li, Celestia S. Higano, Heather H. Cheng, and Catherine M. Tangen, Fred Hutchinson Cancer Research Center, University of Washington; Stephen R. Plymate, Harborview Medical Center, University of Washington, Seattle; Yoshio Inoue, Multicare Regional Cancer Center, Tacoma, WA; Neeraj Agarwal, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT; Sumanta K. Pal, City of Hope, Duarte; David I. Quinn, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA; Ajjai Alva, University of Michigan, Ann Arbor; Elisabeth I. Heath, Karmanos Cancer Center, Wayne State University, Detroit, MI; Elaine T. Lam, University of Colorado, Denver, CO; Shilpa Gupta, H. Lee Moffitt Cancer Center and Research Institute, University of South Florida Morisani College of Medicine, Tampa, FL; Michael B. Lilly, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC; Kim N. Chi, British Columbia Cancer Agency, University of British Columbia, Vancouver, British Columbia, Canada; Nicholas J. Vogelzang, Comprehensive Cancer Centers of Nevada, Las Vegas, NV; and Ian M. Thompson Jr, University of Texas Health Science Center at San Antonio, San Antonio, TX.

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May 2015

HRAS mutations are frequent in inverted urothelial neoplasms.

Hum Pathol 2014 Sep 18;45(9):1957-65. Epub 2014 Jun 18.

Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Electronic address:

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September 2014

Papillary renal cell carcinoma revisited: a comprehensive histomorphologic study with outcome correlations.

Hum Pathol 2014 Jun 20;45(6):1139-46. Epub 2014 Feb 20.

Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Urology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Electronic address:

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June 2014

Hereditary leiomyomatosis and renal cell carcinoma (HLRCC): a rapid autopsy report of metastatic renal cell carcinoma.

Am J Surg Pathol 2014 Apr;38(4):567-77

Departments of *Pathology #Urology †Internal Medicine, Division of Hematology and Oncology ‡Comprehensive Cancer Center, University of Michigan Health System ∥Michigan Center for Translational Pathology ¶Howard Hughes Medical Institute, Ann Arbor, MI §Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY.

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April 2014

Current and proposed molecular diagnostics in a genitourinary service line laboratory at a tertiary clinical institution.

Cancer J 2014 Jan-Feb;20(1):29-42

From the Departments of *Pathology, †Internal Medicine, ‡Comprehensive Cancer Center, University of Michigan Health System; and §Michigan Center for Translational Pathology, Ann Arbor, MI.

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May 2015

Intermittent androgen deprivation therapy in advanced prostate cancer.

Curr Treat Options Oncol 2014 Mar;15(1):127-36

University of Michigan Comprehensive Cancer Center, 1500 East Medical Center Drive, Room 7314, Ann Arbor, MI, 48109-5946, USA.

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March 2014

Primary urethral clear-cell adenocarcinoma: comprehensive analysis by surgical pathology, cytopathology, and next-generation sequencing.

Am J Pathol 2014 Mar 3;184(3):584-91. Epub 2014 Jan 3.

Department of Pathology, University of Michigan Health System, Ann Arbor, Michigan; Comprehensive Cancer Center, University of Michigan Health System, Ann Arbor, Michigan; Michigan Center for Translational Pathology, Ann Arbor, Michigan; Department of Urology, University of Michigan Health System, Ann Arbor, Michigan; Howard Hughes Medical Institute, Ann Arbor, Michigan.

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March 2014

Phase II trial of combination nab-paclitaxel, carboplatin and gemcitabine in first line therapy of advanced urothelial carcinoma.

Invest New Drugs 2014 Feb 10;32(1):188-94. Epub 2013 Dec 10.

University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA,

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February 2014

The changing natural history of metastatic prostate cancer.

Cancer J 2013 Jan-Feb;19(1):19-24

Division of Hematology/Oncology, Department of Internal Medicine, and University of Michigan Comprehensive Cancer Center, Ann Arbor, MI 48109, USA.

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July 2013

Perioperative chemotherapy for upper tract urothelial cancer.

Nat Rev Urol 2012 Apr 10;9(5):266-73. Epub 2012 Apr 10.

Department of Hematology and Oncology, Division of Internal Medicine, University of Michigan, C351 Med Inn, SPC 5848, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA.

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April 2012

Epigenetics in prostate cancer.

Prostate Cancer 2011 30;2011:580318. Epub 2011 Nov 30.

Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana 46202, USA.

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August 2012

Hypomethylating agents for urologic cancers.

Future Oncol 2011 Mar;7(3):447-63

Baylor College of Medicine & Michael E DeBakey VA Medical Center, Houston, TX 77030, USA.

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March 2011

Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8.

Science 2004 Jun 6;304(5676):1500-2. Epub 2004 May 6.

Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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June 2004