Ajay Goel

Ajay Goel

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Ajay Goel

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Intratumoral Levels Predict Therapeutic Response to Neoadjuvant Chemotherapy in Esophageal Squamous Cell Carcinoma.

Clin Cancer Res 2019 Oct 29;25(20):6170-6179. Epub 2019 Jul 29.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute, Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-0318DOI Listing
October 2019

Pathways of Colorectal Carcinogenesis.

Gastroenterology 2019 Oct 14. Epub 2019 Oct 14.

Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Center for Cancer Risk Assessment, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1053/j.gastro.2019.08.059DOI Listing
October 2019

Novel candidates in early-onset familial colorectal cancer.

Fam Cancer 2019 Sep 25. Epub 2019 Sep 25.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A. Sammons Cancer Center, Dallas, TX, USA.

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http://link.springer.com/10.1007/s10689-019-00145-5
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http://dx.doi.org/10.1007/s10689-019-00145-5DOI Listing
September 2019

Lynch-like syndrome is as frequent as Lynch syndrome in early-onset nonfamilial nonpolyposis colorectal cancer.

Int J Cancer 2019 Aug 23;145(3):705-713. Epub 2019 Feb 23.

Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d' Investigacions Biomediques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/ijc.32160DOI Listing
August 2019

Molecular Characterization of Sessile Serrated Adenoma/Polyps From a Large African American Cohort.

Gastroenterology 2019 08 17;157(2):572-574. Epub 2019 Apr 17.

Department of Medicine and Cancer Center, Howard University College of Medicine, Washington, DC; Department of Pathology, Howard University College of Medicine, Washington, DC.

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https://linkinghub.elsevier.com/retrieve/pii/S00165085193670
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http://dx.doi.org/10.1053/j.gastro.2019.04.015DOI Listing
August 2019

Gene Expression Signature in Surgical Tissues and Endoscopic Biopsies Identifies High-Risk T1 Colorectal Cancers.

Gastroenterology 2019 06 21;156(8):2338-2341.e3. Epub 2019 Feb 21.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538250PMC
June 2019

A real-time loop mediated isothermal amplification assay for molecular detection of Burkholderia mallei, the aetiological agent of a zoonotic and re-emerging disease glanders.

Acta Trop 2019 Jun 5;194:189-194. Epub 2019 Apr 5.

Bioprocess Technology Division, Defence Research and Development Establishment, Jhansi Road, Gwalior, 474002, India.

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http://dx.doi.org/10.1016/j.actatropica.2019.04.004DOI Listing
June 2019

Circulating miR-203 derived from metastatic tissues promotes myopenia in colorectal cancer patients.

J Cachexia Sarcopenia Muscle 2019 Jun 25;10(3):536-548. Epub 2019 Mar 25.

Department of Gastrointestinal and Pediatric Surgery, Division of Reparative Medicine, Institute of Life Sciences, Mie University Graduate School of Medicine, Japan.

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http://dx.doi.org/10.1002/jcsm.12403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596405PMC
June 2019

The Journal Club: Highlights on Recent Papers-7.

Noncoding RNA 2019 Jun 11;5(2). Epub 2019 Jun 11.

Department of Microbiology & Plant Pathology, Center for Plant Cell Biology, Institute for Integrative Genome Biology, University of California, 900 University Ave., Riverside, CA 92521, USA.

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http://dx.doi.org/10.3390/ncrna5020040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631633PMC
June 2019

Genome-wide Discovery of a Novel Gene-expression Signature for the Identification of Lymph Node Metastasis in Esophageal Squamous Cell Carcinoma.

Ann Surg 2019 May;269(5):879-886

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute, Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, TX.

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http://Insights.ovid.com/crossref?an=00000658-900000000-9578
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http://dx.doi.org/10.1097/SLA.0000000000002622DOI Listing
May 2019

Detection of circulating microRNAs with Ago2 complexes to monitor the tumor dynamics of colorectal cancer patients during chemotherapy.

Int J Cancer 2019 05 7;144(9):2169-2180. Epub 2019 Jan 7.

Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

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http://dx.doi.org/10.1002/ijc.31960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590166PMC
May 2019

Melatonin-mediated downregulation of thymidylate synthase as a novel mechanism for overcoming 5-fluorouracil associated chemoresistance in colorectal cancer cells.

Carcinogenesis 2019 May;40(3):422-431

Center for Gastrointestinal Research; Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute, Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1093/carcin/bgy186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514450PMC
May 2019

Oligomeric proanthocyanidins (OPCs) from grape seed extract suppress the activity of ABC transporters in overcoming chemoresistance in colorectal cancer cells.

Carcinogenesis 2019 May;40(3):412-421

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott and White Research Institute, and Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1093/carcin/bgy184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514448PMC
May 2019

Molecular subtyping of colorectal cancer: Recent progress, new challenges and emerging opportunities.

Semin Cancer Biol 2019 04 18;55:37-52. Epub 2018 May 18.

Department of Biomedical Sciences, City University of Hong Kong, Hong Kong. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2018.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240404PMC
April 2019

A comprehensive methylation signature identifies lymph node metastasis in esophageal squamous cell carcinoma.

Int J Cancer 2019 03 16;144(5):1160-1169. Epub 2018 Oct 16.

Center for Gastrointestinal Research; Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1002/ijc.31755DOI Listing
March 2019

DNA Mismatch Repair Deficiency and Immune Checkpoint Inhibitors in Gastrointestinal Cancers.

Gastroenterology 2019 03 19;156(4):890-903. Epub 2018 Dec 19.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2018.11.071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409193PMC
March 2019

Activation of AZIN1 RNA editing is a novel mechanism that promotes invasive potential of cancer-associated fibroblasts in colorectal cancer.

Cancer Lett 2019 Mar 21;444:127-135. Epub 2018 Dec 21.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A Sammons Cancer Center, Baylor University Medical Center, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2018.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339593PMC
March 2019

Development of a rapid and sensitive recombinase polymerase amplification-lateral flow assay for detection of Burkholderia mallei.

Transbound Emerg Dis 2019 Mar 15;66(2):1016-1022. Epub 2019 Feb 15.

Bioprocess Technology Division, Defence Research and Development Establishment, Gwalior, India.

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http://doi.wiley.com/10.1111/tbed.13126
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http://dx.doi.org/10.1111/tbed.13126DOI Listing
March 2019

A genomewide transcriptomic approach identifies a novel gene expression signature for the detection of lymph node metastasis in patients with early stage gastric cancer.

EBioMedicine 2019 Mar 13;41:268-275. Epub 2019 Feb 13.

Center for Gastrointestinal Research, Baylor Scott & White Research Institute and Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.01.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441863PMC
March 2019

TIAM1 promotes chemoresistance and tumor invasiveness in colorectal cancer.

Cell Death Dis 2019 Mar 19;10(4):267. Epub 2019 Mar 19.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, TX, USA.

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http://www.nature.com/articles/s41419-019-1493-5
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http://dx.doi.org/10.1038/s41419-019-1493-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425043PMC
March 2019

Cancer stem cell-associated miRNAs serve as prognostic biomarkers in colorectal cancer.

JCI Insight 2019 Mar 21;4(6). Epub 2019 Mar 21.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A. Sammons Cancer Center, Baylor Research Institute and Sammons Cancer, Dallas Texas, USA.

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http://dx.doi.org/10.1172/jci.insight.125294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483002PMC
March 2019

Transcriptomic expression profiling identifies ITGBL1, an epithelial to mesenchymal transition (EMT)-associated gene, is a promising recurrence prediction biomarker in colorectal cancer.

Mol Cancer 2019 02 4;18(1):19. Epub 2019 Feb 4.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, 3410 Worth Street, Suite 610, Dallas, TX, 75246, USA.

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http://dx.doi.org/10.1186/s12943-019-0945-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360655PMC
February 2019

c-Myb and its Effector COX-2 as an Indicator Associated with Prognosis and Therapeutic Outcome in Colorectal Cancer.

J Cancer 2019 28;10(7):1601-1610. Epub 2019 Feb 28.

Department of Pathology, Shanghai Tenth People's Hospital, Tongji University, Shanghai200072, P.R. China.

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http://dx.doi.org/10.7150/jca.27261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548004PMC
February 2019

Piwi-interacting RNAs (piRNAs) and cancer: Emerging biological concepts and potential clinical implications.

Biochim Biophys Acta Rev Cancer 2019 01 30;1871(1):160-169. Epub 2018 Dec 30.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A Sammons Cancer Center, Baylor Research Institute and Sammons Cancer Center, Baylor University Medical Center, Dallas, TX 75246-2017, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2018.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392428PMC
January 2019

Evidence that TNF-β induces proliferation in colorectal cancer cells and resveratrol can down-modulate it.

Exp Biol Med (Maywood) 2019 Jan 19;244(1):1-12. Epub 2019 Jan 19.

1 Musculoskeletal Research Group and Tumor Biology, Chair of Vegetative Anatomy, Faculty of Medicine, Ludwig-Maximilian-University Munich, Munich 80336, Germany.

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http://dx.doi.org/10.1177/1535370218824538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362535PMC
January 2019

A randomized, double blind, placebo controlled, multicenter clinical trial to assess the efficacy and safety of Emblica officinalis extract in patients with dyslipidemia.

BMC Complement Altern Med 2019 Jan 22;19(1):27. Epub 2019 Jan 22.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas, 3410 Worth Street, Suite 610, Dallas, TX, 75246, USA.

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http://dx.doi.org/10.1186/s12906-019-2430-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341673PMC
January 2019

MicroRNAs as potential liquid biopsy biomarkers in colorectal cancer: A systematic review.

Biochim Biophys Acta Rev Cancer 2018 12 29;1870(2):274-282. Epub 2018 May 29.

Baylor Scott & White Research Institute and Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2018.05.006DOI Listing
December 2018

Enhanced AZIN1 RNA editing and overexpression of its regulatory enzyme ADAR1 are important prognostic biomarkers in gastric cancer.

J Transl Med 2018 12 18;16(1):366. Epub 2018 Dec 18.

Center for Gastrointestinal Research and Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A. Sammons Cancer Center, Baylor University Medical Center, 3410 Worth Street, Suite 610, Dallas, TX, 75246, USA.

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https://translational-medicine.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12967-018-1740-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299520PMC
December 2018

Features of Immune Cells and the Tumor-Associated Stroma Tango as Prognostic Factors in Patients With Pancreatic Ductal Adenocarcinoma.

Gastroenterology 2018 11 6;155(5):1312-1314. Epub 2018 Oct 6.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085183509
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http://dx.doi.org/10.1053/j.gastro.2018.10.008DOI Listing
November 2018

A combination of curcumin and oligomeric proanthocyanidins offer superior anti-tumorigenic properties in colorectal cancer.

Sci Rep 2018 09 14;8(1):13869. Epub 2018 Sep 14.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1038/s41598-018-32267-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138725PMC
September 2018

Epigenetic biomarkers in gastrointestinal cancers: The current state and clinical perspectives.

Semin Cancer Biol 2018 08 15;51:36-49. Epub 2017 Dec 15.

Department of Molecular Oncology, Institute for Cancer Research, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway; K.G. Jebsen Colorectal Cancer Research Centre, Oslo University Hospital, Oslo, Norway; Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2017.12.004DOI Listing
August 2018

Genome-wide Discovery and Identification of a Novel miRNA Signature for Recurrence Prediction in Stage II and III Colorectal Cancer.

Clin Cancer Res 2018 08 7;24(16):3867-3877. Epub 2018 Mar 7.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-17-3236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095767PMC
August 2018

Clinical impact of endometrial cancer stratified by genetic mutational profiles, POLE mutation, and microsatellite instability.

PLoS One 2018 16;13(4):e0195655. Epub 2018 Apr 16.

Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0195655PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901772PMC
July 2018

hDNA2 nuclease/helicase promotes centromeric DNA replication and genome stability.

EMBO J 2018 07 17;37(14). Epub 2018 May 17.

Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope, Duarte, CA, USA

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http://dx.doi.org/10.15252/embj.201796729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043852PMC
July 2018

Resveratrol Chemosensitizes TNF-β-Induced Survival of 5-FU-Treated Colorectal Cancer Cells.

Nutrients 2018 Jul 12;10(7). Epub 2018 Jul 12.

Musculoskeletal Research Group and Tumour Biology, Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, Ludwig-Maximilian-University Munich, Pettenkoferstrasse 11, D-80336 Munich, Germany.

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http://www.mdpi.com/2072-6643/10/7/888
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http://dx.doi.org/10.3390/nu10070888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073304PMC
July 2018

Methylation and Expression Status Does Not Predict Response to 5-FU-based Chemotherapy in Colorectal Cancer.

Clin Cancer Res 2018 06 13;24(12):2820-2827. Epub 2018 Mar 13.

Center for Gastrointestinal Research; Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A Sammons Cancer Center, Baylor Research Institute and Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-2940DOI Listing
June 2018

Reply.

Gastroenterology 2018 06 8;154(8):2274-2275. Epub 2018 May 8.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A Sammons Cancer Center, Baylor Research Institute and Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1053/j.gastro.2018.05.013DOI Listing
June 2018

AZIN1 RNA editing confers cancer stemness and enhances oncogenic potential in colorectal cancer.

JCI Insight 2018 06 21;3(12). Epub 2018 Jun 21.

Center for Gastrointestinal Research and Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Baylor Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1172/jci.insight.99976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124399PMC
June 2018

Lifestyle Factors, Colorectal Tumor Methylation, and Survival Among African Americans and European Americans.

Sci Rep 2018 06 21;8(1):9470. Epub 2018 Jun 21.

Department of Medicine, University of North Carolina, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1038/s41598-018-27738-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013500PMC
June 2018

Mechanistic insights into anticancer properties of oligomeric proanthocyanidins from grape seeds in colorectal cancer.

Carcinogenesis 2018 05;39(6):767-777

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott and White Research Institute and Charles A Sammons Cancer Center, Dallas, TX, USA.

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https://academic.oup.com/carcin/article/39/6/767/4978174
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http://dx.doi.org/10.1093/carcin/bgy034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972632PMC
May 2018

Enhanced production and purification of recombinant surface array protein (Sap) for use in detection of .

3 Biotech 2018 May 11;8(5):254. Epub 2018 May 11.

Bioprocess Technology Division, Defence Research and Development Establishment, Jhansi Road, Gwalior, 474002 India.

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http://dx.doi.org/10.1007/s13205-018-1269-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948184PMC
May 2018

A MicroRNA Signature Associated With Metastasis of T1 Colorectal Cancers to Lymph Nodes.

Gastroenterology 2018 03 2;154(4):844-848.e7. Epub 2017 Dec 2.

Center for Gastrointestinal Research and Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute, Charles A Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.11.275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847452PMC
March 2018

Re: Cumulative burden of inflammation predicts colorectal neoplasia risk in ulcerative colitis: a large single-centre study.

Gut 2018 Mar 13. Epub 2018 Mar 13.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute, Baylor University Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1136/gutjnl-2018-316205DOI Listing
March 2018

RAP80 is an independent prognosis biomarker for the outcome of patients with esophageal squamous cell carcinoma.

Cell Death Dis 2018 02 2;9(2):146. Epub 2018 Feb 2.

Department of Clinical Laboratory Medicine, Shanghai Tenth People's Hospital of Tongji University, Shanghai, China.

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http://www.nature.com/articles/s41419-017-0177-2
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http://dx.doi.org/10.1038/s41419-017-0177-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833679PMC
February 2018

V600E mutation is a predictive indicator of upfront chemotherapy for stage IV colorectal cancer.

Oncol Lett 2018 Feb 8;15(2):2195-2201. Epub 2017 Dec 8.

Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Chūgoku 700-8558, Japan.

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http://dx.doi.org/10.3892/ol.2017.7553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776948PMC
February 2018

Oligomeric proanthocyanidins (OPCs) target cancer stem-like cells and suppress tumor organoid formation in colorectal cancer.

Sci Rep 2018 02 20;8(1):3335. Epub 2018 Feb 20.

Center for Gastrointestinal Research, Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A Sammons Cancer Center, Baylor University Medical Center, Dallas, TX, 75246, USA.

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http://dx.doi.org/10.1038/s41598-018-21478-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820273PMC
February 2018

Accuracy of four mononucleotide-repeat markers for the identification of DNA mismatch-repair deficiency in solid tumors.

J Transl Med 2018 01 12;16(1). Epub 2018 Jan 12.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott& White Research Institute and Charles A Sammons Cancer Center, Baylor University Medical Center, 3410 Worth Street, Suite 610, Dallas, TX, 75246, USA.

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http://dx.doi.org/10.1186/s12967-017-1376-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767035PMC
January 2018

A RNA-Sequencing approach for the identification of novel long non-coding RNA biomarkers in colorectal cancer.

Sci Rep 2018 01 12;8(1):575. Epub 2018 Jan 12.

Center for Gastrointestinal Research, Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A Sammons Cancer Center, Baylor University Medical Center, Dallas, TX, 75246, USA.

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http://dx.doi.org/10.1038/s41598-017-18407-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766599PMC
January 2018

Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal cancer.

Mol Cancer 2018 01 30;17(1):16. Epub 2018 Jan 30.

Center for Gastrointestinal Research; Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A Sammons Cancer Center, Baylor University Medical Center, 3410 Worth Street, Suite 610, Dallas, TX, 75246, USA.

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http://dx.doi.org/10.1186/s12943-018-0767-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791351PMC
January 2018

A Panel of Methylated MicroRNA Biomarkers for Identifying High-Risk Patients With Ulcerative Colitis-Associated Colorectal Cancer.

Gastroenterology 2017 12 25;153(6):1634-1646.e8. Epub 2017 Aug 25.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A. Sammons Cancer Center, Baylor Research Institute and Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085173607
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http://dx.doi.org/10.1053/j.gastro.2017.08.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748293PMC
December 2017

FOXD3 Regulates CSC Marker, DCLK1-S, and Invasive Potential: Prognostic Implications in Colon Cancer.

Mol Cancer Res 2017 12 29;15(12):1678-1691. Epub 2017 Aug 29.

Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas.

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http://dx.doi.org/10.1158/1541-7786.MCR-17-0287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748292PMC
December 2017

IGF-1R: SUMO-ing its weight in chemoresistant colorectal cancer.

Authors:
Ajay Goel

Br J Cancer 2017 12 9;117(12):1733-1735. Epub 2017 Nov 9.

Center for Gastrointestinal Research and Center for Translational Genomics and Oncology, Michael A Ramsay Chair in Cancer Genomics, Baylor Scott and White Research Institute and Charles A. Sammons Cancer Center, 3410 Worth Street, Suite 610, Dallas, TX 75246, USA.

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http://dx.doi.org/10.1038/bjc.2017.377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729482PMC
December 2017

Effect of cell cycle duration on somatic evolutionary dynamics.

Evol Appl 2017 12 12;10(10):1121-1129. Epub 2017 Oct 12.

Department of Ecology and Evolutionary Biology University of California Irvine CA USA.

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http://dx.doi.org/10.1111/eva.12518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680637PMC
December 2017

Utilizing biomarkers in colorectal cancer: an interview with Ajay Goel.

Authors:
Ajay Goel

Future Oncol 2017 Dec 23;13(28):2511-2514. Epub 2017 Nov 23.

Center for Gastrointestinal Research; Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute, Charles A Sammons Cancer Center, Baylor University Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.2217/fon-2017-0495DOI Listing
December 2017

The Holy Grail of Curcumin and its Efficacy in Various Diseases: Is Bioavailability Truly a Big Concern?

J Restor Med 2017 Dec;6(1):27-36

Center for Gastrointestinal Research; Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A Sammons Cancer Center, Baylor University Medical Center, Dallas, TX, USA.

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https://journal.restorativemedicine.org/index.php/journal/ar
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http://dx.doi.org/10.14200/jrm.2017.6.0101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424351PMC
December 2017

Curcumin sensitizes pancreatic cancer cells to gemcitabine by attenuating PRC2 subunit EZH2, and the lncRNA PVT1 expression.

Carcinogenesis 2017 10;38(10):1036-1046

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott and White Research Institute and Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, TX 75246, USA.

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https://academic.oup.com/carcin/article/38/10/1036/3924866
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http://dx.doi.org/10.1093/carcin/bgx065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862331PMC
October 2017

Effect of aspirin on tumour cell colony formation and evolution.

J R Soc Interface 2017 09;14(134)

Department of Ecology and Evolutionary Biology, University of California, Irvine, CA 92617, USA.

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http://dx.doi.org/10.1098/rsif.2017.0374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636273PMC
September 2017

Resveratrol Regulates Colorectal Cancer Cell Invasion by Modulation of Focal Adhesion Molecules.

Nutrients 2017 Sep 27;9(10). Epub 2017 Sep 27.

Musculoskeletal Research Group and Tumour Biology, Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, LMU Munich, Pettenkoferstrasse 11, D-80336 Munich, Germany.

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http://dx.doi.org/10.3390/nu9101073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691690PMC
September 2017

SNORA21 - An Oncogenic Small Nucleolar RNA, with a Prognostic Biomarker Potential in Human Colorectal Cancer.

EBioMedicine 2017 Aug 12;22:68-77. Epub 2017 Jul 12.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute, Charles A Sammons Cancer Center, Baylor University Medical Center, Dallas, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552212PMC
August 2017

Circular RNA ciRS-7-A Promising Prognostic Biomarker and a Potential Therapeutic Target in Colorectal Cancer.

Clin Cancer Res 2017 Jul 7;23(14):3918-3928. Epub 2017 Feb 7.

Center for Gastrointestinal Research; Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute, Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-16-2541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511556PMC
July 2017

Diagnostic Potential of Cell-Free and Exosomal MicroRNAs in the Identification of Patients with High-Risk Colorectal Adenomas.

PLoS One 2016 19;11(10):e0160722. Epub 2016 Oct 19.

Department of Gastrointestinal and Pediatric Surgery, Division of Reparative Medicine, Institute of Life Sciences, Graduate School of Medicine, Mie University, Mie 514-8507, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160722PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070810PMC
June 2017

Emerging Role of MicroRNAs as Liquid Biopsy Biomarkers in Gastrointestinal Cancers.

Clin Cancer Res 2017 May 31;23(10):2391-2399. Epub 2017 Jan 31.

Center for Gastrointestinal Research; Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A. Sammons Cancer Center, Baylor Research Institute and Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433899PMC
May 2017

The critical role of acute flaccid paralysis surveillance in the Global Polio Eradication Initiative.

Int Health 2017 05;9(3):156-163

World Health Organization, Geneva, Switzerland.

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http://dx.doi.org/10.1093/inthealth/ihx016DOI Listing
May 2017

Essential turmeric oils enhance anti-inflammatory efficacy of curcumin in dextran sulfate sodium-induced colitis.

Sci Rep 2017 04 11;7(1):814. Epub 2017 Apr 11.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott & White Research Institute and Charles A Sammons Cancer Center, Baylor Research Institute and Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1038/s41598-017-00812-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429743PMC
April 2017

Exportin-5 Functions as an Oncogene and a Potential Therapeutic Target in Colorectal Cancer.

Clin Cancer Res 2017 Mar 23;23(5):1312-1322. Epub 2016 Aug 23.

Center for Gastrointestinal Research; Center for Epigenetics, Cancer Prevention, and Cancer Genomics, Baylor Research Institute and Charles A Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435115PMC
March 2017

Aspirin-Induced Chemoprevention and Response Kinetics Are Enhanced by PIK3CA Mutations in Colorectal Cancer Cells.

Cancer Prev Res (Phila) 2017 Mar 2;10(3):208-218. Epub 2017 Feb 2.

Center for Gastrointestinal Research; Center for Translational Genomics and Oncology, Baylor Scott and White Research Institute and Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1158/1940-6207.CAPR-16-0175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337164PMC
March 2017

MiR-139-5p as a novel serum biomarker for recurrence and metastasis in colorectal cancer.

Sci Rep 2017 03 6;7:43393. Epub 2017 Mar 6.

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott &White Research Institute and Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1038/srep43393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338356PMC
March 2017

Transcriptional Regulator CNOT3 Defines an Aggressive Colorectal Cancer Subtype.

Cancer Res 2017 02 29;77(3):766-779. Epub 2016 Nov 29.

Department of Medical Oncology and Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290184PMC
February 2017

H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer.

EBioMedicine 2016 Nov 19;13:113-124. Epub 2016 Oct 19.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Center for RNA Interference and Non-Coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2016.10.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264449PMC
November 2016

FOXM1 and FOXQ1 Are Promising Prognostic Biomarkers and Novel Targets of Tumor-Suppressive miR-342 in Human Colorectal Cancer.

Clin Cancer Res 2016 Oct 9;22(19):4947-4957. Epub 2016 May 9.

Center for Gastrointestinal Research, Center for Epigenetics, Cancer Prevention and Cancer Genomics, Baylor Research Institute and Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-0360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435114PMC
October 2016

Presentation of the Julius M. Friedenwald Medal to C. Richard Boland, MD, AGAF.

Gastroenterology 2016 06 30;150(7):1673-1677. Epub 2016 Apr 30.

Center for Gastrointestinal Research, Center for Epigenetics, Cancer Prevention and Cancer Genomics, Baylor Research Institute and Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1053/j.gastro.2016.04.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951086PMC
June 2016

DNA methylation patterns as noninvasive biomarkers and targets of epigenetic therapies in colorectal cancer.

Epigenomics 2016 05 22;8(5):685-703. Epub 2016 Apr 22.

Center for Translational Genomics & Oncology, Baylor Scott & White Research Institute & Sammons Cancer Center, Baylor University Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.2217/epi-2015-0013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928499PMC
May 2016