Ajay D Wasan

Ajay D Wasan

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Ajay D Wasan

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Using formative evaluation methods to improve clinical implementation efforts: Description and an example.

Psychiatry Res 2019 Aug 26:112532. Epub 2019 Aug 26.

Department of Psychiatry, University of Pittsburgh School of Medicine, UPMC Center for Integrative Medicine, 580 S. Aiken Avenue, Suite 310, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1016/j.psychres.2019.112532DOI Listing
August 2019

Somatotopically specific primary somatosensory connectivity to salience and default mode networks encodes clinical pain.

Pain 2019 Jul;160(7):1594-1605

Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, United States.

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http://dx.doi.org/10.1097/j.pain.0000000000001541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586503PMC
July 2019

Multivariate resting-state functional connectivity predicts responses to real and sham acupuncture treatment in chronic low back pain.

Neuroimage Clin 2019 28;23:101885. Epub 2019 May 28.

Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA; Department of Radiology, Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.101885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551557PMC
May 2019

Psychosocial interventions for chronic pain and comorbid prescription opioid use disorders: A narrative review of the literature.

J Opioid Manag 2018 Sep/Oct;14(5):345-358

Vice Chair for Pain Medicine, Department of Anesthesiology; Professor, Anesthesiology and Psychiatry, University of Pittsburgh Medical Center, UPMC Pain Medicine, Centre Commons, Pittsburgh, Pennsylvania.

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http://www.wmpllc.org/ojs-2.4.2/index.php/jom/article/view/2
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http://dx.doi.org/10.5055/jom.2018.0467DOI Listing
March 2019

A narrative review of data collection and analysis guidelines for comparative effectiveness research in chronic pain using patient-reported outcomes and electronic health records.

J Pain Res 2019 24;12:491-500. Epub 2019 Jan 24.

Department of Anesthesiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA,

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http://dx.doi.org/10.2147/JPR.S184023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353217PMC
January 2019

Chronic pain clinic efficiency analysis: optimization through use of the Gantt diagram and visit diagnoses.

J Pain Res 2019 17;12:1-8. Epub 2018 Dec 17.

University of Pittsburgh Physicians, Pittsburgh, PA, USA,

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http://dx.doi.org/10.2147/JPR.S173345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301303PMC
December 2018

Operationalizing Multidisciplinary Assessment and Treatment as a Quality Metric for Interventional Pain Practices.

Pain Med 2018 05;19(5):910-913

Division of Pain Medicine, Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1093/pm/pnx079DOI Listing
May 2018

A Functional Neuroimaging Study of Expectancy Effects on Pain Response in Patients With Knee Osteoarthritis.

J Pain 2018 05 8;19(5):515-527. Epub 2018 Jan 8.

Psychiatric Neuroimaging, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts.

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https://linkinghub.elsevier.com/retrieve/pii/S15265900183000
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http://dx.doi.org/10.1016/j.jpain.2017.12.260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927817PMC
May 2018

A Conceptual Framework for Understanding Unintended Prolonged Opioid Use.

Mayo Clin Proc 2017 Dec 3;92(12):1822-1830. Epub 2017 Nov 3.

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine, Rochester, MN.

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http://dx.doi.org/10.1016/j.mayocp.2017.10.010DOI Listing
December 2017

Reduced insula habituation associated with amplification of trigeminal brainstem input in migraine.

Cephalalgia 2017 Oct 13;37(11):1026-1038. Epub 2016 Aug 13.

1 Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1177/0333102416665223DOI Listing
October 2017

Long-Term Effects of Repeated Injections of Local Anesthetic With or Without Corticosteroid for Lumbar Spinal Stenosis: A Randomized Trial.

Arch Phys Med Rehabil 2017 08 8;98(8):1499-1507.e2. Epub 2017 Apr 8.

Comparative Effectiveness, Cost and Outcomes Research Center, University of Washington, Seattle, WA; Department of Radiology, University of Washington, Seattle, WA; Department of Health Services, University of Washington, Seattle, WA.

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http://dx.doi.org/10.1016/j.apmr.2017.02.029DOI Listing
August 2017

Modulation of brainstem activity and connectivity by respiratory-gated auricular vagal afferent nerve stimulation in migraine patients.

Pain 2017 08;158(8):1461-1472

aDepartment of Radiology, Martinos Center for Biomedical Imaging, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USAbNeurovascular Science Group, Fundación Cardiovascular de Colombia, Floridablanca, ColombiacDepartment of Medicine, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USAdHarvard-MIT Division of Health Sciences and Technology, Harvard Medical School, Boston, MA, USAeClinical Research Division, Korea Institute of Oriental Medicine, Daejeon, KoreafDepartment of Electronics, Information and Bioengineering, Politecnico di Milano, Milano, ItalygDepartment of Anesthesia and Critical Care, Massachusetts General Hospital, Boston, MA, USAhDepartment of Radiology, Logan University, Chesterfield, MO, USAiDepartment of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USAjDepartment of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USAkGillberg Neuropsychiatry Center, Gothenburg University, Gothenburg, Sweden.

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http://dx.doi.org/10.1097/j.pain.0000000000000930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517046PMC
August 2017

Human Posterior Insula Functional Connectivity Differs Between Electrical Pain and the Resting State.

Brain Connect 2016 12 21;6(10):786-794. Epub 2016 Oct 21.

1 Department of Anesthesiology, School of Medicine, University of Pittsburgh , Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1089/brain.2016.0436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175422PMC
December 2016

Assessment of physical function and participation in chronic pain clinical trials: IMMPACT/OMERACT recommendations.

Pain 2016 Sep;157(9):1836-50

aCentre for Medical Education, School of Medicine, Cardiff University, Cardiff, Wales, United Kingdom bDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA cDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA dDepartment of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA eDepartment of Occupational Science and Occupational Therapy, University of Toronto, ON, Canada fInstitute for Work and Health, University of Toronto, ON, Canada gDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI, USA hInstitute for Work and Health, University of Toronto, ON, Canada iDepartment of Neurology, University of Rochester, Rochester, NY, USA jDepomed, Newark, CA, USA kLORAGroup LLC, Royal Oak, MD, USA lDepartment of Health Services Research University of Maryland, Baltimore, MD, USA mPublic Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA nDivision of Infection and Immunity, Cardiff University, Cardiff, Wales, United Kingdom oNIHR Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom pInstitute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom qAmerican Chronic Pain Association, Rocklin, CA, USA rDepartment of Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA sDepartment of Neurology, Harvard University, Cambridge, MA, USA tDepartment of Anesthesiology, Queen's University, Ottawa, ON, Canada uDepartment of Psychiatry, Duke University Medical Center, Durham, NC, USA vPfizer, Inc, Durham, NC, USA wClinical and Rehabilitative Medicine Research Program, United States Army Medical Research and Materiel Command xPurdue Pharma L.P., Stamford, CT, USA yDepartment of Veterans Affairs, Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA zDepartment of Psychiatry and Psychology, Yale University, New Haven, CT, USA aa

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http://dx.doi.org/10.1097/j.pain.0000000000000577DOI Listing
September 2016

Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations.

Pain 2016 Sep;157(9):1851-71

aHarvard Medical School, Boston, MA, USA bUniversity of Rochester, Rochester, NY, USA cUniversity of Washington, Seattle, WA, USA dStanford University, Palo Alto, CA, USA eEast Carolina University, Greenville, NC, USA fOslo University Hospital, Oslo, Norway and Karolinska Institute, Stockholm, Sweden gWashington University, St. Louis, MO, USA hAalborg University, Aalborg, Denmark iHôpital Ambroise Paré, APHP and INSERM U 987, Boulogne-Billancourt, France and University Versailles Saint Quentin, Versailles, France jUniversity of Kiel, Kiel, Germany kMetroHealth Medical Center, Cleveland, OH, USA lDepomed, Newark, CA, USA mLORA Group, LLC, Royal Oak, MD, USA nUniversity of Maryland, Baltimore, MD, USA oTufts University, Boston, MA, USA pEli Lilly, Indianapolis IN, USA qAmerican Chronic Pain Association, Rocklin, CA, USA rJohnson and Johnson, Titusville, NJ, USA sUniversity of Florida, Gainesville, FL, USA tAnalgesic Solutions, Natick, MA, USA uCollegium Pharmaceutical, Inc., Canton, MA, USA vAstellas Pharma, Northbrook, IL, USA wNational Institutes of Health, Bethesda, MD, USA xArlington, VA, USA yImperial College, London, United Kingdom zPfizer, Groton, CT, USA aaColumbia University, New York, NY, USA bbSDG LLC, Cambridge, MA, USA ccJazz Pharmaceuticals, Palo Alto, CA, USA ddCeres Consulting, Fort Montgomery, NY, USA eeChronic Pain Research Alliance, North Kingstown, RI, USA ffZalicus, Cambridge, MA, USA ggUniversity of Pittsburgh, Pittsburgh, PA, USA hhPurdue Pharma, Stamford, CT, USA iiRambam Health Care Campus and Technion Faculty of Medicine, Haifa, Israel.

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http://dx.doi.org/10.1097/j.pain.0000000000000602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965275PMC
September 2016

The Role of Psychosocial Processes in the Development and Maintenance of Chronic Pain.

J Pain 2016 09;17(9 Suppl):T70-92

Department of Anesthesiology, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1016/j.jpain.2016.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012303PMC
September 2016

Variability in conditioned pain modulation predicts response to NSAID treatment in patients with knee osteoarthritis.

BMC Musculoskelet Disord 2016 07 13;17:284. Epub 2016 Jul 13.

Department of Anesthesiology, Harvard Medical School, Brigham & Women's Hospital, 850 Boylston St, Suite 302, Chestnut Hill, MA, 02467, USA.

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http://dx.doi.org/10.1186/s12891-016-1124-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944243PMC
July 2016

Pain intensity rating training: results from an exploratory study of the ACTTION PROTECCT system.

Pain 2016 May;157(5):1056-64

aDepartment of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA bDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA, USA cInstitute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA dSchool of Professional Psychology, Pacific University, Hillsboro, OR, USA eDepartment of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA fDepartment of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA gDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA hEvidera, Seattle, WA, USA iLORA Group, LLC, Royal Oak, MD, USA jUniversity of Maryland, Baltimore, MD, USA kDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada lDepartment of Psychology and Neuroscience, Dalhousie University, Halifax, NS, Canada mCentre for Pediatric Pain Research, IWK Health Center, Halifax, NS, Canada nPalm Beach Gardens, FL, USA oAmerican Chronic Pain Association, Rocklin, CA, USA pDesjardins Associates, Maplewood, NJ, USA qJohnson & Johnson, Titusville, NJ, USA rDepartment of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USA sDepartment of Anesthesia, University of Pennsylvania, Philadelphia, PA, USA tDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, USA uDepartment of Anesthesiology & Perioperative Medicine, Queen's University, Kingston, ON, Canada vDepartment of Biomedical & Molecular Sciences, Queen's University, Kingston, ON, Canada wJazz Pharmaceuticals, Palo Alto, CA, USA xPurdue Pharma L.P., Stamford, CT, USA yVA Connecticut Healthcare System, West Haven, CT, USA zDepartment of Psychiatry, Yale University, New Haven, CT, USA aaDepartment of Neurology, Yale University, New Haven, CT, USA bbDepartment of Psychology, Yale University, New Haven, CT, USA ccCollegium Pharmaceutical,

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http://dx.doi.org/10.1097/j.pain.0000000000000502DOI Listing
May 2016

Authors' Reply to Manchikanti.

Spine (Phila Pa 1976) 2016 Feb;41(3):E183-4

VA Puget Sound Health Care System, Seattle, WA; University of Washington, Seattle, WA; Dallas VA Medical Center, Dallas, TX; Brigham and Women's Hospital, Boston, MA; University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1097/BRS.0000000000001142DOI Listing
February 2016

Fibromyalgia is characterized by altered frontal and cerebellar structural covariance brain networks.

Neuroimage Clin 2015 4;7:667-77. Epub 2015 Mar 4.

Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA ; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (HMS), Chestnut Hill, MA 02467, USA ; Department of Biomedical Engineering, College of Electronics and Information, Kyung Hee University, Yongin, 449-701, South Korea.

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http://dx.doi.org/10.1016/j.nicl.2015.02.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379388PMC
January 2016

Optimizing and Interpreting Insular Functional Connectivity Maps Obtained During Acute Experimental Pain: The Effects of Global Signal and Task Paradigm Regression.

Brain Connect 2015 Dec 3;5(10):649-57. Epub 2015 Aug 3.

1 Department of Anesthesiology, Center for Pain Research, University of Pittsburgh , Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1089/brain.2015.0354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684650PMC
December 2015

Advances in Biomedical Imaging, Bioengineering, and Related Technologies for the Development of Biomarkers of Pancreatic Disease: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases and National Institute of Biomedical Imaging and Bioengineering Workshop.

Pancreas 2015 Nov;44(8):1185-94

From the *Department of Biomedical Engineering, University of Virginia, Charlottesville, VA; †Eppley Cancer Institute, University of Nebraska School of Medicine, Omaha, NE; ‡Division of Gastroenterology, Hepatology and Nutrition, Departments of Medicine and Anesthesiology and Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA; §Office of Cancer Nanotechnology Research and the Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD; ∥Division of Gastroenterology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD; ¶Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD; and #Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1097/MPA.0000000000000552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608388PMC
November 2015

Psychiatric Comorbidity Is Associated Prospectively with Diminished Opioid Analgesia and Increased Opioid Misuse in Patients with Chronic Low Back Pain.

Anesthesiology 2015 Oct;123(4):861-72

From the Departments of Anesthesiology and Psychiatry (A.D.W.), University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; and Departments of Anesthesiology (A.D.W., E.M., R.R.E., S.S.N., A.J.D., D.J., R.N.J.), Psychiatry (R.R.E., R.N.J.), Internal Medicine (J.N.K.), Orthopaedic Surgery (J.N.K.), and Physical Medicine and Rehabilitation (Z.I.), Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/ALN.0000000000000768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573512PMC
October 2015

Short-term improvements in disability mediate patient satisfaction after epidural corticosteroid injections for symptomatic lumbar spinal stenosis.

Spine (Phila Pa 1976) 2015 Sep;40(17):1363-70

*Division of Rehabilitation Care Services and Seattle Epidemiologic Research and Information Center (ERIC), VA Puget Sound Health Care System, Seattle, WA †Department of Rehabilitation Medicine, University of Washington, Seattle, WA ‡Department of Biostatistics, University of Washington, Seattle, WA §Comparative Effectiveness, Cost and Outcomes Research Center, University of Washington, Seattle, WA ¶Department of Radiology, University of Washington, Seattle, WA ‖Department of Health Services, University of Washington, Seattle, WA **Department of Psychiatry & Behavioral Sciences, University of Washington, Seattle, WA ††Department of Physical Medicine and Rehabilitation, VA North Texas Health Care System and UT Southwestern Medical Center, Dallas, TX ‡‡Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA §§Spine Unit, Harvard Vanguard Medical Associates, Boston, MA; and ¶¶ Departments of Anesthesiology and Psychiatry, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1097/BRS.0000000000001000DOI Listing
September 2015

The lateral prefrontal cortex mediates the hyperalgesic effects of negative cognitions in chronic pain patients.

J Pain 2015 Aug 30;16(8):692-9. Epub 2015 Apr 30.

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Chestnut Hill, Massachusetts.

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http://dx.doi.org/10.1016/j.jpain.2015.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522376PMC
August 2015

Self-reports of medication side effects and pain-related activity interference in patients with chronic pain: a longitudinal cohort study.

Pain 2015 Jun;156(6):1092-100

aDepartment of Anesthesiology, Harvard Medical School, Brigham and Women's Hospital Pain Management Center, Chestnut Hill, MA, USA bDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA cDepartment of Social and Behavioral Sciences, Harvard School of Public Health, Boston, MA, USA dUPMC Pain Medicine, Departments of Anesthesiology and Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.

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http://pdfs.journals.lww.com/pain/2015/06000/Self_reports_of
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/j.pain.0000000000000154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431924PMC
June 2015

Fibromyalgia symptoms and cirrhosis.

Dig Dis Sci 2015 May 30;60(5):1482-9. Epub 2014 Nov 30.

Center for Health Equity Research and Promotion, VA Pittsburgh Healthcare System, University Drive (151C), Pittsburgh, PA, 15240, USA,

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http://dx.doi.org/10.1007/s10620-014-3453-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688457PMC
May 2015

Inflammation, psychiatric symptoms, and opioid use are associated with pain and disability in patients with cirrhosis.

Clin Gastroenterol Hepatol 2015 May 5;13(5):1009-16. Epub 2014 Nov 5.

Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1016/j.cgh.2014.10.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846465PMC
May 2015

Instruments to Identify Prescription Medication Misuse, Abuse, and Related Events in Clinical Trials: An ACTTION Systematic Review.

J Pain 2015 May 4;16(5):389-411. Epub 2015 Feb 4.

Departments of Anesthesiology and Neurology, and Center for Human Experimental Therapeutics, University of Rochester School of Medicine and Dentistry, Rochester, New York.

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http://dx.doi.org/10.1016/j.jpain.2015.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460153PMC
May 2015

Multicenter survey of attitudes and perceptions of pain medicine fellows toward the use of lateral versus contralateral-oblique fluoroscopic view for interlaminar cervical epidural injection.

Pain Med 2015 Apr 26;16(4):692-5. Epub 2015 Feb 26.

Division of Pain Medicine, Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1111/pme.12649DOI Listing
April 2015

Evidence for brain glial activation in chronic pain patients.

Brain 2015 Mar 12;138(Pt 3):604-15. Epub 2015 Jan 12.

1 MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1093/brain/awu377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339770PMC
March 2015

Effects of testosterone replacement in men with opioid-induced androgen deficiency: a randomized controlled trial.

Pain 2015 Feb;156(2):280-8

aThe Research Program in Men's Health: Aging and Metabolism, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA bDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA cDepartment of Medicine, Boston University School of Medicine, Boston, MA, USA dDepartment of Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA eDepartments of Anesthesiology and Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1097/01.j.pain.0000460308.86819.aaDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036339PMC
February 2015

Distraction analgesia in chronic pain patients: the impact of catastrophizing.

Anesthesiology 2014 Dec;121(6):1292-301

From the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, Massachusetts (K.L.S., S.G., R.N.J., R.R.E.); Department of Psychiatry and Behavioral Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland (C.C., A.D.W.); Department of Anesthesiology and Psychiatry, University of Pittsburgh Medical Center (C.C., A.D.W.); Department of Psychiatry, Brigham and Women's Hospital (M.O.M., R.N.J., R.R.E.); and Center for Pain and the Brain, P.A.I.N. Group, Boston Children's Hospital, Boston, Massachusetts (D.B.).

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http://dx.doi.org/10.1097/ALN.0000000000000465DOI Listing
December 2014

Assessing craving and its relationship to subsequent prescription opioid use among treatment-seeking prescription opioid dependent patients.

Drug Alcohol Depend 2014 Dec 16;145:121-6. Epub 2014 Oct 16.

Division of Alcohol and Drug Abuse, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA; Department of Psychiatry, Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.drugalcdep.2014.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254575PMC
December 2014

Phenotype matters: the absence of a positive association between cortical thinning and chronic low back pain when controlling for salient clinical variables.

Clin J Pain 2014 Oct;30(10):839-45

Departments of *Anesthesiology §Psychiatry, Brigham and Women's Hospital Departments of †Radiology ‡Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA Departments of ∥Anesthesiology ¶Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1097/AJP.0000000000000043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103969PMC
October 2014

The association between catastrophizing and craving in patients with chronic pain prescribed opioid therapy: a preliminary analysis.

Pain Med 2014 Oct 10;15(10):1757-64. Epub 2014 Mar 10.

Department of Anesthesiology, Harvard Medical School, Brigham & Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1111/pme.12416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160420PMC
October 2014

The subjective psychoactive effects of oral dronabinol studied in a randomized, controlled crossover clinical trial for pain.

Clin J Pain 2014 Jun;30(6):472-8

Departments of *Anesthesiology, Perioperative, and Pain Medicine ‡Psychiatry, Brigham and Women's Hospital §Behavioral Psychopharmacology Research Laboratory, McLean Hospital †Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/AJP.0000000000000022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013220PMC
June 2014

Characteristics of medical inpatients with acute pain and suspected non-medical use of opioids.

Am J Addict 2013 Sep-Oct;22(5):515-20. Epub 2013 Apr 11.

Department of Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts 02115,

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http://doi.wiley.com/10.1111/j.1521-0391.2013.12016.x
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http://dx.doi.org/10.1111/j.1521-0391.2013.12016.xDOI Listing
April 2014

Efficacy vs effectiveness and explanatory vs pragmatic: where is the balance point in pain medicine research?

Authors:
Ajay D Wasan

Pain Med 2014 Apr;15(4):539-40

Departments of Anesthesiology and Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1111/pme.12420DOI Listing
April 2014

The association between negative affect and prescription opioid misuse in patients with chronic pain: the mediating role of opioid craving.

J Pain 2014 Jan 12;15(1):90-100. Epub 2013 Oct 12.

Department of Anesthesiology, Harvard Medical School, Brigham & Women's Hospital, Boston, Massachusetts; Department of Psychiatry, Harvard Medical School, Brigham & Women's Hospital, Boston, Massachusetts.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877217PMC
January 2014

Disrupted brain circuitry for pain-related reward/punishment in fibromyalgia.

Arthritis Rheumatol 2014 Jan;66(1):203-12

Massachusetts General Hospital, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/art.38191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516215PMC
January 2014

Optimizing urine drug testing for monitoring medication compliance in pain management.

Pain Med 2013 Dec 30;14(12):1813-20. Epub 2013 Jul 30.

Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1111/pme.12207DOI Listing
December 2013

Sex differences in the stability of conditioned pain modulation (CPM) among patients with chronic pain.

Pain Med 2013 Nov 7;14(11):1757-68. Epub 2013 Aug 7.

Department of Anesthesiology, Harvard Medical School, Brigham & Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1111/pme.12220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833959PMC
November 2013

Sustained deep-tissue pain alters functional brain connectivity.

Pain 2013 Aug 11;154(8):1343-51. Epub 2013 Apr 11.

MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, USA.

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http://dx.doi.org/10.1016/j.pain.2013.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700646PMC
August 2013

A longitudinal study of the reliability of acupuncture deqi sensations in knee osteoarthritis.

Evid Based Complement Alternat Med 2013 1;2013:204259. Epub 2013 Jul 1.

Department of Psychiatry, Massachusetts General Hospital, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1155/2013/204259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713327PMC
August 2013

S1 is associated with chronic low back pain: a functional and structural MRI study.

Mol Pain 2013 Aug 21;9:43. Epub 2013 Aug 21.

Department of Psychiatry, Massachusetts General Hospital, Charlestown, Harvard Medical School, 120 2nd Ave,, Room 101, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1186/1744-8069-9-43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765748PMC
August 2013

Alteration in pain modulation in women with persistent pain after lumpectomy: influence of catastrophizing.

J Pain Symptom Manage 2013 Jul 25;46(1):30-42. Epub 2012 Oct 25.

Department of Anesthesiology, Harvard Medical School, Brigham and Women's Hospital, Chestnut Hill, MA 02467, USA.

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http://dx.doi.org/10.1016/j.jpainsymman.2012.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713099PMC
July 2013

Ketamine decreases postoperative pain scores in patients taking opioids for chronic pain: results of a prospective, randomized, double-blind study.

Pain Med 2013 Jun 22;14(6):925-34. Epub 2013 Apr 22.

Department of Anesthesiology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1111/pme.12086DOI Listing
June 2013

Can pragmatic trials help us better understand chronic pain and improve treatment?

Pain 2013 May 7;154(5):643-6. Epub 2013 Mar 7.

California Pacific Medical Center Research Institute, San Francisco, CA 94107, USA.

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May 2013

Relationship of negative affect and outcome of an opioid therapy trial among low back pain patients.

Pain Pract 2013 Mar 11;13(3):173-81. Epub 2012 Jun 11.

Pain Management Center, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1111/j.1533-2500.2012.00575.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869183PMC
March 2013

Default mode network connectivity encodes clinical pain: an arterial spin labeling study.

Pain 2013 Jan 27;154(1):24-33. Epub 2012 Oct 27.

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (HMS), Boston, MA, USA.

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http://dx.doi.org/10.1016/j.pain.2012.07.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534957PMC
January 2013

Disentangling linear and nonlinear brain responses to evoked deep tissue pain.

Pain 2012 Oct 9;153(10):2140-51. Epub 2012 Aug 9.

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.pain.2012.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445769PMC
October 2012

An appraisal of William Thomas Green Morton's life as a narcissistic personality.

Anesthesiology 2012 Jul;117(1):10-4

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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July 2012

The use of functional neuroimaging to evaluate psychological and other non-pharmacological treatments for clinical pain.

Neurosci Lett 2012 Jun 14;520(2):156-64. Epub 2012 Mar 14.

Department of Psychiatry, Massachusetts General Hospital (MGH)/Harvard Medical School (HMS), Boston, MA, USA.

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http://dx.doi.org/10.1016/j.neulet.2012.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810294PMC
June 2012

The catechol-O-methyltransferase (COMT) val158met polymorphism affects brain responses to repeated painful stimuli.

PLoS One 2011 21;6(11):e27764. Epub 2011 Nov 21.

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221673PMC
April 2012

Craving of prescription opioids in patients with chronic pain: a longitudinal outcomes trial.

J Pain 2012 Feb 14;13(2):146-54. Epub 2012 Jan 14.

Pain Management Center, Department of Anesthesiology, Perioperative and Pain Medicine, Harvard Medical School, Boston, Massachusetts, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274819PMC
February 2012

Elevated pain sensitivity in chronic pain patients at risk for opioid misuse.

J Pain 2011 Sep 16;12(9):953-63. Epub 2011 Jun 16.

Department of Anesthesiology, Harvard Medical School, Brigham & Women's Hospital, Chestnut Hill, Massachusetts 0246, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164595PMC
September 2011

Neural correlates of chronic low back pain measured by arterial spin labeling.

Anesthesiology 2011 Aug;115(2):364-74

Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286828PMC
August 2011

Substance misuse treatment for high-risk chronic pain patients on opioid therapy: a randomized trial.

Pain 2010 Sep 23;150(3):390-400. Epub 2010 Mar 23.

Department of Anesthesiology, Pain Management Center, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02467, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910796PMC
September 2010

Differences in pain, psychological symptoms, and gender distribution among patients with left- vs right-sided chronic spinal pain.

Pain Med 2010 Sep 27;11(9):1373-80. Epub 2010 Jul 27.

Department of Anesthesiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972385PMC
September 2010

A fMRI evaluation of lamotrigine for the treatment of trigeminal neuropathic pain: pilot study.

Pain Med 2010 Jun 11;11(6):920-41. Epub 2010 May 11.

P.A.I.N. Group, Brain Imaging Center, McLean Hospital, Belmont, MA 02478, USA.

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June 2010

Gender differences in risk factors for aberrant prescription opioid use.

J Pain 2010 Apr 27;11(4):312-20. Epub 2009 Nov 27.

Pain Management Center, Departments of Anesthesia and Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02467, USA.

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http://dx.doi.org/10.1016/j.jpain.2009.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847642PMC
April 2010

Enhanced reactivity to pain in patients with rheumatoid arthritis.

Arthritis Res Ther 2009 4;11(3):R61. Epub 2009 May 4.

Department of Anesthesiology, Harvard Medical School, Brigham & Women's Hospital, Chestnut Hill, MA 02467, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714104PMC
March 2010

Spinal cord stimulation in a workers' compensation population: how difficult it can be to interpret a clinical trial.

Authors:
Ajay D Wasan

Pain 2010 Jan 11;148(1):3-4. Epub 2009 Nov 11.

Brigham and Women's Hospital/Harvard Medical School, Anesthesiology, Perioperative and Pain Medicine, Pain Mangement Center 850 Boylston St., Boston, MA 02467, USA.

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January 2010

The prevalence and significance of cannabis use in patients prescribed chronic opioid therapy: a review of the extant literature.

Pain Med 2009 Nov 29;10(8):1434-41. Epub 2009 Sep 29.

Division of Addiction Medicine, Department of Psychiatry, University of Florida College of Medicine, Gainesville, FLorida, USA.

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November 2009

Does report of craving opioid medication predict aberrant drug behavior among chronic pain patients?

Clin J Pain 2009 Mar-Apr;25(3):193-8

Department of Anesthesia, Pain Management Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1097/AJP.0b013e318193a6c4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664529PMC
June 2009

Practice patterns and treatment choices among psychiatrists in New Delhi, India: a qualitative and quantitative study.

Soc Psychiatry Psychiatr Epidemiol 2009 Feb 14;44(2):109-19. Epub 2008 Jul 14.

Departments of Anesthesiology and Psychiatry, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.

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February 2009

Psychopathology predicts the outcome of medial branch blocks with corticosteroid for chronic axial low back or cervical pain: a prospective cohort study.

BMC Musculoskelet Disord 2009 Feb 16;10:22. Epub 2009 Feb 16.

Department of Anesthesiology, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1186/1471-2474-10-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652420PMC
February 2009

Reasons for participation in pain research: can they indicate a lack of informed consent?

Pain Med 2009 Jan 24;10(1):111-9. Epub 2008 Jul 24.

Departments of Anesthesiology and Psychiatry, Harvard Medical School/Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1111/j.1526-4637.2008.00481.xDOI Listing
January 2009

Safety and efficacy of duloxetine in the treatment of diabetic peripheral neuropathic pain in older patients.

Curr Drug Saf 2009 Jan;4(1):22-9

Department of Anesthesiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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January 2009

Interpreting urine drug tests: prevalence of morphine metabolism to hydromorphone in chronic pain patients treated with morphine.

Pain Med 2008 Oct 28;9(7):918-23. Epub 2007 Aug 28.

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1111/j.1526-4637.2007.00354.xDOI Listing
October 2008

Patients with chronic pain on opioid therapy taking dronabinol: incidence of false negatives using radioimmunoassay.

J Opioid Manag 2008 Jan-Feb;4(1):21-6

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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May 2008

Efficacy of dronabinol as an adjuvant treatment for chronic pain patients on opioid therapy.

J Pain 2008 Mar 21;9(3):254-64. Epub 2007 Dec 21.

Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1016/j.jpain.2007.10.018DOI Listing
March 2008