Publications by authors named "Aisheng Dong"

121 Publications

Super Early Scan of PSMA PET/CT in Evaluating Primary and Metastatic Lesions of Prostate Cancer.

Molecules 2022 Jul 21;27(14). Epub 2022 Jul 21.

Department of Nuclear Medicine, Shanghai Changhai Hospital, Shanghai 200433, China.

Ga-prostate specific membrane antigen (PSMA)-11 PET/CT has been widely used in the diagnosis of prostate cancer (PCa); however, the urine lead shielding resulting from the urinary metabolism of tracers may obstruct the detection of surrounding metastasis. In this research, the additive value of super early scanning in diagnosing primary lesions and metastasis in the pelvic cavity was evaluated. Firstly, the differentiation efficiency of Ga-PSMA-11 PET scanned at 3 min post-injection (min P.I.) was measured in PSMA-positive (22rv1 cells) and PSMA-negative (PC3 cells) model mice. Secondly, 106 patients were scanned at 3 min P.I. for the pelvic cavity and then scanned as a standard protocol at 45 min P.I. In the results, the differential diagnosis of PSMA expression was completely reflected as early as 3 min P.I. for mice models. For patients, when correlated with the Gleason score, the quantitative results of the super early scan displayed a comparable correlation coefficient with the routine scan. The target to bladder ratios increased from 1.44 ± 2.40 at 45 min to 10.10 ± 19.10 at 3 min ( < 0.001) for the primary lesions, and it increased from 0.99 ± 1.88 to 9.27 ± 23.03 for metastasis. Meanwhile, the target to background ratios increased from 2.21 ± 2.44 at 3 min to 19.13 ± 23.93 at 45 min ( < 0.001) for the primary lesions, and it increased from 1.68 ± 2.71 to 12.04 ± 18.73 ( < 0.001) for metastasis. In conclusion, super early scanning of Ga-PSMA-11 PET/CT added referable information for metastasis detection in order to avoid disturbing tracer activity in the urinary system.
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http://dx.doi.org/10.3390/molecules27144661DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318552PMC
July 2022

FDG PET/CT in Unilateral Renal Metastasis From Colon Cancer.

Authors:
Xia Ji Aisheng Dong

Clin Nucl Med 2022 Jul 19. Epub 2022 Jul 19.

Department of Nuclear Medicine, Changhai Hospital, Navy Medical University, Shanghai, China.

Abstract: Renal metastasis from colon cancer is rare. We describe FDG PET/CT findings in a case with a right renal and a postcaval lymph node metastasis from colon cancer. Both the renal tumor and postcaval lymph node showed increased FDG uptake with SUVmax of 6.1 for the renal tumor and 5.5 for the postcaval lymph node. The imaging findings mimicked a primary renal cancer with postcaval lymph node metastasis.
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http://dx.doi.org/10.1097/RLU.0000000000004326DOI Listing
July 2022

FDG PET/CT in a Case With Primary Poorly Differentiated Urothelial-Type Adenocarcinoma of the Prostate.

Clin Nucl Med 2022 Aug 4;47(8):736-738. Epub 2022 Apr 4.

From the Departments of Nuclear Medicine.

Abstract: Primary urothelial-type adenocarcinoma of the prostate is extremely rare. We describe FDG PET/CT findings in a case with primary poorly differentiated urothelial-type adenocarcinoma of the prostate with pelvic lymph node metastases. Both the prostate tumor and its metastatic lesions showed intense FDG uptake. The patient had normal serum prostate-specific antigen and elevated carcinoembryonic antigen levels, which may be helpful for the differential diagnosis.
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http://dx.doi.org/10.1097/RLU.0000000000004150DOI Listing
August 2022

Lipid-Poor Renal Angiomyolipoma Mimicking Renal Cell Carcinoma on 68Ga-FAPI-04 PET/CT.

Clin Nucl Med 2022 May 27. Epub 2022 May 27.

From the Department of Nuclear Medicine, the First Affiliated Hospital of Navy Medical University (Changhai Hospital).

Abstract: FAPI PET/CT findings of renal tumors have been rarely reported. We describe 68Ga-FAPI-04 PET/CT findings in 1 case with lipid-poor renal angiomyolipoma and 1 case with high-grade clear cell renal cell carcinoma. Both tumors showed intense 68Ga-FAPI-04 uptake. These 2 cases indicate that lipid-poor renal angiomyolipoma should be included in the differential diagnosis of FAPI-avid renal tumors.
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http://dx.doi.org/10.1097/RLU.0000000000004297DOI Listing
May 2022

FDG PET/CT in a Case With Cellular Schwannoma of the Kidney.

Clin Nucl Med 2022 May 27. Epub 2022 May 27.

From the Shanghai Universal Medical Imaging Diagnostic Center.

Abstract: Schwannoma of the kidney is exceedingly rare. We describe contrast-enhanced CT and FDG PET/CT findings in a case with renal cellular schwannoma. Contrast-enhanced CT showed the enhancing tumor was located in the anterior middle portion of the left kidney, encasing the renal vessels and compressing the renal pelvis. The tumor showed inhomogeneous FDG uptake with SUVmax of 8.6 mimicking renal cell carcinoma. This case indicates renal schwannoma should be included in the differential diagnosis of FDG-avid renal lesions.
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http://dx.doi.org/10.1097/RLU.0000000000004300DOI Listing
May 2022

FDG PET/CT in Prostate Metastasis From Gastric Cancer.

Authors:
Xia Ji Aisheng Dong

Clin Nucl Med 2022 May 19. Epub 2022 May 19.

Department of Nuclear Medicine, Changhai Hospital, Navy Medical University, Shanghai, China.

Abstract: Prostate metastasis from gastric cancer is rare. We report MRI and FDG PET/CT findings in a case with prostate metastasis from gastric cancer. In this case, the prostate metastasis was the first manifestation of the gastric cancer. This case demonstrates the usefulness of FDG PET/CT in identifying the primary gastric cancer and its contribution for an accurate staging. Familiarity with the FDG PET/CT findings of the prostate metastasis may be useful for the differential diagnosis of the hypermetabolic prostate lesions.
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http://dx.doi.org/10.1097/RLU.0000000000004281DOI Listing
May 2022

FDG PET/CT in Eosinophilic Solid and Cystic Renal Cell Carcinoma With Lung Metastases.

Clin Nucl Med 2022 May 19. Epub 2022 May 19.

Department of Pathology, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.

Abstract: Eosinophilic solid and cystic renal cell carcinoma is a recently described emerging renal tumor. Usefulness of FDG PET/CT in the management of eosinophilic solid and cystic renal cell carcinoma has been rarely reported. We describe FDG PET/CT findings in a case of eosinophilic solid and cystic renal cell carcinoma with lung metastases. The primary renal tumor and its metastases showed intense FDG uptake with SUVmax of 29.3 for the primary tumor and 21 for the lung metastases.
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http://dx.doi.org/10.1097/RLU.0000000000004282DOI Listing
May 2022

68 Ga-PSMA-11 and 18 F-FDG PET/CT in a Case of Ductal Adenocarcinoma of the Prostate.

Clin Nucl Med 2022 Sep 20;47(9):836-838. Epub 2022 Apr 20.

From the Departments of Nuclear Medicine.

Abstract: Prostatic ductal adenocarcinoma is an uncommon variant of prostatic carcinoma with aggressive behavior and worse prognosis. We describe 68 Ga-PSMA-11 and FDG PET/CT findings in a case of prostatic ductal adenocarcinoma with pelvic lymph node metastases. The majority of the prostate tumor and all the metastatic lesions showed no significant PSMA uptake but intense FDG uptake. The role of PSMA and FDG PET in the management of prostatic ductal adenocarcinoma needs to be investigated in a large number of patients.
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http://dx.doi.org/10.1097/RLU.0000000000004230DOI Listing
September 2022

Prostate-Specific Membrane Antigen-Avid Bone Metastases From Urothelial Carcinoma of the Bladder.

Clin Nucl Med 2022 Apr 19. Epub 2022 Apr 19.

From the Department of Nuclear Medicine, Changhai Hospital, Navy Medical University, Shanghai, China.

Abstract: Prostate-specific membrane antigen (PSMA) PET findings of urothelial carcinoma were rarely reported. We describe 18F-FDG PET/CT and 68Ga-PSMA-11 PET/MRI findings in a case of urothelial carcinoma of the bladder with bone metastases in the sternum, ribs, spine, pelvis, and femurs. The bone metastases showed isodensity to hyperdensity and mild to intense FDG uptake on FDG PET/CT and moderate to intense PSMA uptake on PSMA PET/MRI. PSMA PET/MRI more clearly delineated the bone metastases compared with FDG PET/CT.
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http://dx.doi.org/10.1097/RLU.0000000000004246DOI Listing
April 2022

FDG PET/CT and Bone Scintigraphy in Desmoplastic Fibroma of the Bone.

Clin Nucl Med 2022 Apr 15. Epub 2022 Apr 15.

Nuclear Medicine, Changhai Hospital, Navy Medical University, Shanghai, China.

Abstract: Desmoplastic fibroma is a very rare benign bone tumor with local aggressiveness. We describe imaging findings in 2 cases with desmoplastic fibroma of the bone. One case had a desmoplastic fibroma in the right distal femur, showing bone destruction with sclerotic margins and inhomogeneous FDG uptake. The other case had a desmoplastic fibroma in the left ninth rib, showing progressive peripheral enhancement and increased 99mTc-MDP uptake.
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http://dx.doi.org/10.1097/RLU.0000000000004186DOI Listing
April 2022

68 Ga-FAPI-04 Versus 18 F-FDG PET/CT in a Case With Intimal Sarcoma of the Pulmonary Artery.

Clin Nucl Med 2022 Aug 30;47(8):748-750. Epub 2022 Mar 30.

From the Department of Nuclear Medicine, Changhai Hospital, Navy Medical University, Shanghai, China.

Abstract: Intimal sarcoma of the pulmonary artery is a rare entity, mimicking acute or chronic pulmonary thromboembolism. We describe 68 Ga-FAPI-04 and 18 F-FDG PET/CT findings in a case with intimal sarcoma of the pulmonary artery. The intrapulmonary artery tumor showed inhomogeneously increased FDG and FAPI uptake. Compared with FDG PET/CT, FAPI PET/CT more clearly delineated the tumor partially because of a very low background FAPI activity in the walls of the main pulmonary artery and right ventricle, which showed diffuse FDG uptake.
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http://dx.doi.org/10.1097/RLU.0000000000004141DOI Listing
August 2022

68 Ga-FAPI-04 Versus 18 F-FDG PET/CT in a Case of Peutz-Jeghers Syndrome.

Clin Nucl Med 2022 Aug 28;47(8):725-727. Epub 2022 Feb 28.

From the Department of Nuclear Medicine, Changhai Hospital, Navy Medical University, Shanghai, China.

Abstract: Peutz-Jeghers syndrome is a rare inherited hamartomatous polyposis syndrome. We describe 68 Ga-FAPI-04 and 18 F-FDG PET/CT findings in a case of Peutz-Jeghers syndrome with primary duodenal clear cell sarcoma, peritoneal metastases, and multiple intestinal polyps varying in size. The duodenal tumor and its metastases showed increased FDG and FAPI uptake. The peritoneal metastases were delineated more clearly on FAPI PET/CT compared with FDG PET/CT. More interestingly, the intestinal polyps showed increased FDG uptake and no FAPI uptake.
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http://dx.doi.org/10.1097/RLU.0000000000004113DOI Listing
August 2022

Duodenal Ulcer-Induced Gastric Outlet Obstruction Showing Pyloric Wall Thickening and Abnormal FDG Uptake Mimicking Malignancy.

Authors:
Xia Ji Aisheng Dong

Clin Nucl Med 2022 Jul 24;47(7):658-660. Epub 2022 Jan 24.

Department of Nuclear Medicine, Changhai Hospital, Navy Medical University, Shanghai, China.

Abstract: Peptic ulcer disease is the most common benign cause of gastric outlet obstruction, in which mechanical obstruction occurs in the distal stomach, pylorus, or duodenum. We describe a case of gastric outlet obstruction induced by duodenal ulcer showing irregular pyloric wall thickening with marked enhancement on contras-enhanced CT and increased FDG uptake of the pyloric wall on FDG PET/CT mimicking malignancy.
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http://dx.doi.org/10.1097/RLU.0000000000004067DOI Listing
July 2022

Focal FDG Uptake in the Cerebral Parenchyma Beneath the Subdural Hematoma.

Clin Nucl Med 2022 Jun 15;47(6):553-554. Epub 2022 Jan 15.

From the Department of Neurology, Yueyang Hospital of Integrated Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine.

Abstract: Changes in cerebral glucose metabolism after subdural hematoma have been rarely reported. We present a case with acute subdural hematoma detected unexpectedly on FDG PET/CT. Focal intense FDG uptake in the cerebral parenchyma beneath the subdural hematoma was seen on PET. The density of the cerebral parenchyma was normal on CT. The patient received conservative management. He recovered without any complication. This case indicates that familiarity with the changes in cerebral glucose metabolism on PET after subdural hematoma may be helpful for optimal patient care.
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http://dx.doi.org/10.1097/RLU.0000000000004048DOI Listing
June 2022

18F-PSMA-11 PET/MRI in Prostate Adenocarcinoma With Mucinous Features.

Clin Nucl Med 2022 May;47(5):441-443

Nuclear Medicine, Changhai Hospital, Navy Medical University, Shanghai, China.

Abstract: Primary mucinous tumors involving the prostate gland are rare. We describe MRI and 18F-PSMA-11 PET/MRI findings in a case of prostate adenocarcinoma with mucinous features. The prostate tumor showed inhomogeneous hyperintensity on T2-weighted images due to high extracellular mucin content and inhomogeneous 18F-PSMA-11 uptake with SUVmax of 12.5. This case indicates PSMA PET imaging may be helpful for detection of this uncommon variant of prostate adenocarcinoma.
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http://dx.doi.org/10.1097/RLU.0000000000003995DOI Listing
May 2022

FDG PET/CT of Primary Breast Lymphoma in a Man.

Clin Nucl Med 2022 May;47(5):447-448

Department of Nuclear Medicine, Changhai Hospital, Navy Medical University, Shanghai, China.

Abstract: Primary lymphoma of the male breast is extremely rare. We describe FDG PET/CT findings in a man with primary breast lymphoma in his right breast. The breast tumor showed intense FDG uptake mimicking breast carcinoma.
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http://dx.doi.org/10.1097/RLU.0000000000003978DOI Listing
May 2022

FDG PET/CT in a Case of Diffuse Esophageal Adenocarcinoma.

Clin Nucl Med 2022 May;47(5):462-463

From the Shanghai University, Shanghai Universal Medical Imaging Diagnostic Center.

Abstract: Esophageal cancer usually shows focal intense FDG uptake on FDG PET. Diffuse FDG uptake pattern of the esophageal cancer has been rarely reported. We describe FDG PET/CT findings in a case of esophageal adenocarcinoma showing diffusely intense FDG uptake mimicking esophagitis.
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http://dx.doi.org/10.1097/RLU.0000000000003999DOI Listing
May 2022

99mTc-MIBI SPECT/CT and FDG PET/CT in Isolated Bilateral Renal Metastases From Adenoid Cystic Carcinoma of the Maxilla.

Clin Nucl Med 2022 Feb;47(2):e205-e207

Departments of Nuclear Medicine.

Abstract: Renal metastasis from adenoid cystic carcinoma of the head and neck is uncommon. We present 99mTc-MIBI SPECT/CT and FDG PET/CT findings in a case with isolated bilateral renal metastases from adenoid cystic carcinoma of the left maxilla. The metastatic adenoid cystic carcinomas of the kidneys showed photopenia on 99mTc-MIBI SPECT/CT and increased FDG uptake on FDG PET/CT mimicking primary renal cell carcinoma.
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http://dx.doi.org/10.1097/RLU.0000000000003872DOI Listing
February 2022

FDG PET/CT in Isolated Spermatic Cord Metastasis From Colon Cancer.

Authors:
Xia Ji Aisheng Dong

Clin Nucl Med 2022 Jan;47(1):e81-e82

Department of Nuclear Medicine, Changhai Hospital, Navy Medical University, Shanghai, China.

Abstract: Isolated spermatic cord metastasis is extremely rare. We describe FDG PET/CT findings in a case of isolated spermatic cord metastasis from colon cancer detected 27 months after colectomy. The tumor showed intense focal FDG uptake in the right spermatic cord mimicking a primary spermatic cord malignancy.
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http://dx.doi.org/10.1097/RLU.0000000000003744DOI Listing
January 2022

FDG PET/CT in Cryptogenic Multifocal Ulcerating Stenosing Enteropathy.

Clin Nucl Med 2022 Mar;47(3):281-282

From the Shanghai University, Shanghai Universal Medical Imaging Diagnostic Center.

Abstract: Cryptogenic multifocal ulcerating stenosing enteropathy (CMUSE) is a rare and exclusive small intestine disease, characterized by repeated anemia or obstruction resulting from multiple shallow ulcers with strictures in the small intestine. We present a case of CMUSE showing multiple foci of activity in the small bowel on FDG PET/CT. This case indicates that CMUSE should be included in the differential diagnosis of multifocal FDG activity in the small bowel along with lymphoma, carcinoma, tuberculosis, Crohn disease, Behçet disease, and drug-induced enteropathy.
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http://dx.doi.org/10.1097/RLU.0000000000003931DOI Listing
March 2022

FDG PET/CT in Dendritic Fibromyxolipoma of the Thigh.

Clin Nucl Med 2022 Feb;47(2):e208-e209

Nuclear Medicine, Changhai Hospital, Navy Medical University, Shanghai, China.

Abstract: Dendritic fibromyxolipoma is a rare recently described benign soft tissue tumor, which may be misinterpreted histologically as myxoid liposarcoma or myxoid malignant fibrous histiocytoma. We describe FDG PET/CT and MRI findings of a dendritic fibromyxolipoma incidentally detected in a case with rectal adenocarcinoma. The dendritic fibromyxolipoma showed inhomogeneous FDG uptake with SUVmax of 4.0 mimicking malignancy.
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http://dx.doi.org/10.1097/RLU.0000000000003930DOI Listing
February 2022

Solitary Isolated Dural Metastasis From Lung Adenocarcinoma Mimicking Meningioma.

Clin Nucl Med 2022 Mar;47(3):283-285

Department of Pathology, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.

Abstract: Solitary isolated dural metastasis is extremely rare. Distinguishing solitary dural metastasis from meningioma based on radiological findings can be challenging. We describe MRI and FDG PET/CT findings in 2 cases of histologically proved solitary isolated dural metastasis from lung adenocarcinoma. Enhanced brain MRI of the 2 cases showed parafalcine extra-axial, dural-based tumors with hypervascularity mimicking meningioma. Preoperative FDG PET/CT was performed in one case with a known history of lung adenocarcinoma showing intense FDG uptake of the parafalcine tumor. Postoperative FDG PET/CT was performed in the other case showing solitary lung tumor, suggestive of the primary tumor.
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http://dx.doi.org/10.1097/RLU.0000000000003923DOI Listing
March 2022

FDG PET/CT in Isolated Thoracic Vertebral Rosai-Dorfman Disease.

Clin Nucl Med 2022 Feb;47(2):e135-e136

Nuclear Medicine, Changhai Hospital, Navy Medical University, Shanghai, China.

Abstract: Isolated osseous Rosai-Dorfman disease is rare. We describe FDG PET/CT findings of solitary thoracic vertebral Rosai-Dorfman disease without extraosseous involvement. The vertebral lesion caused osteolytic destruction of the vertebral body and showed intense FDG uptake.
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http://dx.doi.org/10.1097/RLU.0000000000003911DOI Listing
February 2022

FDG-Avid Sclerosing Adenosis of the Breast Mimicking Malignancy.

Clin Nucl Med 2022 Feb;47(2):192-194

From the Shanghai Universal Medical Imaging Diagnostic Center, Shanghai University.

Abstract: Sclerosing adenosis is a common benign proliferative disorder of the breast. We describe FDG PET/CT findings in a case of sclerosing adenosis showing focal intense FDG uptake mimicking malignancy. This case indicates that sclerosing adenosis should be included in the differential diagnosis of focal breast FDG accumulation along with malignant and nonmalignant conditions.
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http://dx.doi.org/10.1097/RLU.0000000000003849DOI Listing
February 2022

Diffuse Linear Pattern of Pericardial FDG Activity in Pericardial Metastasis From Squamous Cell Lung Carcinoma.

Clin Nucl Med 2022 Feb;47(2):179-181

Department of Pathology, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.

Abstract: Pericardial metastasis usually shows focal pericardial FDG activity. Diffuse linear pattern of pericardial FDG activity is uncommon. We present a case of pericardial metastasis from squamous cell lung carcinoma showing diffuse linear pericardial FDG activity mimicking tuberculous pericarditis.
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http://dx.doi.org/10.1097/RLU.0000000000003824DOI Listing
February 2022

FDG PET/CT in a Case of Lynch Syndrome With Synchronous Inverted Urothelial Papilloma of the Bladder, Urothelial Carcinoma of the Ureter, and Jejunal Adenocarcinoma.

Clin Nucl Med 2022 Jan;47(1):e11-e13

Department of Pathology, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.

Abstract: A 64-year-old man was referred because of the right ureteral obstruction. CT urography showed an intraluminal enhancing mass in the right midureter and an enhancing nodule in the bladder wall. FDG PET/CT showed increased FDG uptake of the ureteral mass and an unexpected hypermetabolic lesion in the jejunum. The patient underwent transurethral resection of the bladder tumor, right laparoscopic nephroureterectomy, and partial enterectomy. Inverted urothelial papilloma of the bladder, high-grade urothelial carcinoma of the right ureter, and jejunal adenocarcinoma were confirmed by histopathology. Genetic testing of the jejunal adenocarcinoma revealed MSH2 germline mutation, confirming the diagnosis of Lynch syndrome.
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http://dx.doi.org/10.1097/RLU.0000000000003779DOI Listing
January 2022

68Ga-PSMA-11 PET/CT in Isolated Bilateral Adrenal Metastases From Prostate Adenocarcinoma.

Clin Nucl Med 2022 Jan;47(1):e101-e102

Nuclear Medicine, Changhai Hospital, Navy Medical University, Shanghai, China.

Abstract: A 65-year-old man with treated prostate adenocarcinoma underwent 68Ga-PSMA-11 PET/CT scan for restaging due to significantly increased serum PSA levels. PET/CT showed bilateral adrenal masses with high 68Ga-PSMA-11 uptake. There was no other lesion suspicious for metastasis. The laboratory and imaging findings were consisted with isolated bilateral adrenal metastases from prostate adenocarcinoma. The patient received docetaxel chemotherapy in combination with androgen deprivation therapy. PSA levels gradually decreased during chemotherapy. Follow-up MRI showed the bilateral adrenal masses significantly decreased in size. This case demonstrates the usefulness of 68Ga-PSMA-11 PET/CT in identifying atypical metastasis from prostate adenocarcinoma.
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http://dx.doi.org/10.1097/RLU.0000000000003759DOI Listing
January 2022

Metanephric Adenoma Mimicking Renal Cell Carcinoma on 99mTc-MIBI SPECT/CT.

Clin Nucl Med 2021 Sep;46(9):759-760

From the Departments of Radiology.

Abstract: Metanephric adenoma is a rare benign renal tumor. A 49-year-old woman presented with a left renal pelvic mass detected by ultrasound. Enhanced CT of the kidney showed slight enhancement of the mass. For characterization of the mass, 99mTc-MIBI SPECT/CT was performed showing photopenia of the mass. Renal cell carcinoma was suspected. The mass was removed surgically. Metanephric adenoma was confirmed by histopathology. This case indicates that metanephric adenoma can appear cold on 99mTc-MIBI SPECT/CT, mimicking renal cell carcinoma.
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http://dx.doi.org/10.1097/RLU.0000000000003645DOI Listing
September 2021

FDG PET/CT in 3 Cases of Hypertrophic Pachymeningitis Associated With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

Clin Nucl Med 2021 Sep;46(9):744-747

Shanghai Universal Medical Imaging Diagnostic Center.

Abstract: Hypertrophic pachymeningitis associated with antineutrophil cytoplasmic antibody-associated vasculitis is a rare dural inflammatory disorder. We describe MRI and FDG PET/CT findings in 3 cases of hypertrophic pachymeningitis associated with antineutrophil cytoplasmic antibody-associated vasculitis. Enhanced brain MRI of the 3 cases showed linear enhancement of the thickened dura matter involving the skull base, tentorium, and/or convexity. On FDG PET/CT, the thickened dura matter showed diffusely increased FDG uptake with SUVmax ranging from 5.8 to 11.3. Familiarity with these MRI and FDG PET/CT findings is helpful for correct diagnosis and treatment.
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http://dx.doi.org/10.1097/RLU.0000000000003605DOI Listing
September 2021

FDG PET/CT in Disseminated Intracranial and Intramedullary Spinal Cord Tuberculomas.

Clin Nucl Med 2021 03;46(3):266-269

Nuclear Medicine, Changhai Hospital, Navy Military Medical University, Shanghai, China.

Abstract: A 54-year-old woman was referred because of dizziness with fatigue for 2 months. MRI of the head and spinal cord revealed multiple ring or homogeneous enhancing nodules in the brain and spinal cord, concerning for metastases. FDG PET/CT showed multiple hypermetabolic nodules in the brain and spinal cord corresponding to the gadolinium-enhanced nodules and diffuse FDG uptake in the bilateral lower lobes of the lungs. Chest high-resolution CT showed diffuse, bilateral miliary opacities, most predominant in the lower lobes. The imaging findings and results of cerebrospinal fluid analysis were consistent with disseminated central nervous system tuberculomas with miliary pulmonary tuberculosis.
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http://dx.doi.org/10.1097/RLU.0000000000003483DOI Listing
March 2021
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