Publications by authors named "Aisheng Dong"

97 Publications

Diffuse Linear Pattern of Pericardial FDG Activity in Pericardial Metastasis From Squamous Cell Lung Carcinoma.

Clin Nucl Med 2021 Jul 20. Epub 2021 Jul 20.

From the Department of Cardiothoracic Surgery, The Second Affiliated Hospital, Jiaxing University, Jiaxing, Zhejiang Province Department of Nuclear Medicine, Changhai Hospital, Navy Medical University Department of Pathology, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.

Abstract: Pericardial metastasis usually shows focal pericardial FDG activity. Diffuse linear pattern of pericardial FDG activity is uncommon. We present a case of pericardial metastasis from squamous cell lung carcinoma showing diffuse linear pericardial FDG activity mimicking tuberculous pericarditis.
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http://dx.doi.org/10.1097/RLU.0000000000003824DOI Listing
July 2021

FDG PET/CT in a Case of Lynch Syndrome With Synchronous Inverted Urothelial Papilloma of the Bladder, Urothelial Carcinoma of the Ureter, and Jejunal Adenocarcinoma.

Clin Nucl Med 2021 Jun 25. Epub 2021 Jun 25.

From the Department of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia Department of Nuclear Medicine, Changhai Hospital, Navy Medical University Department of Pathology, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.

Abstract: A 64-year-old man was referred because of the right ureteral obstruction. CT urography showed an intraluminal enhancing mass in the right midureter and an enhancing nodule in the bladder wall. FDG PET/CT showed increased FDG uptake of the ureteral mass and an unexpected hypermetabolic lesion in the jejunum. The patient underwent transurethral resection of the bladder tumor, right laparoscopic nephroureterectomy, and partial enterectomy. Inverted urothelial papilloma of the bladder, high-grade urothelial carcinoma of the right ureter, and jejunal adenocarcinoma were confirmed by histopathology. Genetic testing of the jejunal adenocarcinoma revealed MSH2 germline mutation, confirming the diagnosis of Lynch syndrome.
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http://dx.doi.org/10.1097/RLU.0000000000003779DOI Listing
June 2021

68Ga-PSMA-11 PET/CT in Isolated Bilateral Adrenal Metastases From Prostate Adenocarcinoma.

Clin Nucl Med 2021 Jun 10. Epub 2021 Jun 10.

From the Department of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia Departments of Urology Nuclear Medicine, Changhai Hospital, Navy Medical University, Shanghai, China.

Abstract: A 65-year-old man with treated prostate adenocarcinoma underwent 68Ga-PSMA-11 PET/CT scan for restaging due to significantly increased serum PSA levels. PET/CT showed bilateral adrenal masses with high 68Ga-PSMA-11 uptake. There was no other lesion suspicious for metastasis. The laboratory and imaging findings were consisted with isolated bilateral adrenal metastases from prostate adenocarcinoma. The patient received docetaxel chemotherapy in combination with androgen deprivation therapy. PSA levels gradually decreased during chemotherapy. Follow-up MRI showed the bilateral adrenal masses significantly decreased in size. This case demonstrates the usefulness of 68Ga-PSMA-11 PET/CT in identifying atypical metastasis from prostate adenocarcinoma.
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http://dx.doi.org/10.1097/RLU.0000000000003759DOI Listing
June 2021

Metanephric Adenoma Mimicking Renal Cell Carcinoma on 99mTc-MIBI SPECT/CT.

Clin Nucl Med 2021 Apr 5. Epub 2021 Apr 5.

From the Departments of Radiology Nuclear Medicine, Changhai Hospital, Navy Military Medical University, Shanghai, China.

Abstract: Metanephric adenoma is a rare benign renal tumor. A 49-year-old woman presented with a left renal pelvic mass detected by ultrasound. Enhanced CT of the kidney showed slight enhancement of the mass. For characterization of the mass, 99mTc-MIBI SPECT/CT was performed showing photopenia of the mass. Renal cell carcinoma was suspected. The mass was removed surgically. Metanephric adenoma was confirmed by histopathology. This case indicates that metanephric adenoma can appear cold on 99mTc-MIBI SPECT/CT, mimicking renal cell carcinoma.
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http://dx.doi.org/10.1097/RLU.0000000000003645DOI Listing
April 2021

FDG PET/CT in 3 Cases of Hypertrophic Pachymeningitis Associated With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

Clin Nucl Med 2021 Mar 16. Epub 2021 Mar 16.

From the School of Medicine, Shanghai University Shanghai Universal Medical Imaging Diagnostic Center Department of Nuclear Medicine, Changhai Hospital, Navy Military Medical University, Shanghai, China.

Abstract: Hypertrophic pachymeningitis associated with antineutrophil cytoplasmic antibody-associated vasculitis is a rare dural inflammatory disorder. We describe MRI and FDG PET/CT findings in 3 cases of hypertrophic pachymeningitis associated with antineutrophil cytoplasmic antibody-associated vasculitis. Enhanced brain MRI of the 3 cases showed linear enhancement of the thickened dura matter involving the skull base, tentorium, and/or convexity. On FDG PET/CT, the thickened dura matter showed diffusely increased FDG uptake with SUVmax ranging from 5.8 to 11.3. Familiarity with these MRI and FDG PET/CT findings is helpful for correct diagnosis and treatment.
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http://dx.doi.org/10.1097/RLU.0000000000003605DOI Listing
March 2021

FDG PET/CT in Disseminated Intracranial and Intramedullary Spinal Cord Tuberculomas.

Clin Nucl Med 2021 03;46(3):266-269

Nuclear Medicine, Changhai Hospital, Navy Military Medical University, Shanghai, China.

Abstract: A 54-year-old woman was referred because of dizziness with fatigue for 2 months. MRI of the head and spinal cord revealed multiple ring or homogeneous enhancing nodules in the brain and spinal cord, concerning for metastases. FDG PET/CT showed multiple hypermetabolic nodules in the brain and spinal cord corresponding to the gadolinium-enhanced nodules and diffuse FDG uptake in the bilateral lower lobes of the lungs. Chest high-resolution CT showed diffuse, bilateral miliary opacities, most predominant in the lower lobes. The imaging findings and results of cerebrospinal fluid analysis were consistent with disseminated central nervous system tuberculomas with miliary pulmonary tuberculosis.
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http://dx.doi.org/10.1097/RLU.0000000000003483DOI Listing
March 2021

Ileal Ulcer Associated With a Large Bezoar Mimicking Malignancy on FDG PET/CT.

Clin Nucl Med 2021 Jan;46(1):93-94

Department of Nuclear Medicine, Changhai Hospital, Navy Military Medical University, Shanghai, China.

A 34-year-old woman presented with abdominal pain for 2 months. Abdominal CT revealed a large bezoar in the distal ileum with surrounding thickened ileal wall and enlarged mesentery lymph nodes. On FDG PET/CT, the thickened ileal wall and enlarged mesentery lymph nodes showed increased FDG uptake. Ileal malignancy with mesentery lymph node metastasis was suspected. The distal ileum and enlarged mesentery lymph nodes were removed. Benign ileal ulcer and mesentery reactive lymphoid hyperplasia were confirmed by histopathology.
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http://dx.doi.org/10.1097/RLU.0000000000003364DOI Listing
January 2021

Solitary Acute Inflammatory Demyelinating Lesion of the Cervical Spinal Cord Mimicking Malignancy on FDG PET/CT.

Clin Nucl Med 2020 Dec;45(12):1023-1025

Nuclear Medicine, Changhai Hospital, Navy Military Medical University, Shanghai, China.

A 43-year-old woman presented with numbness of the left hand and leg for 4 weeks. MRI of the spinal cord revealed an intramedullary lesion with central nodular enhancement at the C3 level. Primary tumor or metastasis of the cervical spinal cord was suspected. FDG PET/CT showed focal hypermetabolism of the spinal cord corresponding to the gadolinium-enhanced nodule. The patient underwent resection of the cervical spinal cord lesion. Histopathological findings of the resected specimens were consistent with acute inflammatory demyelinating lesion.
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http://dx.doi.org/10.1097/RLU.0000000000003287DOI Listing
December 2020

FDG PET/CT of Hepatoid Adenocarcinoma of the Gallbladder.

Clin Nucl Med 2020 Nov;45(11):927-928

Department of Nuclear Medicine, Changhai Hospital, Navy Military Medical University, Shanghai, China.

Primary hepatoid adenocarcinoma of the gallbladder is rare. A 67-year-old woman presented with right upper quadrant abdominal pain with elevated α-fetoprotein level. Abdominal ultrasound and MRI showed a tumor in the gallbladder with normal liver. FDG PET/CT showed increased FDG uptake of the gallbladder tumor with retroperitoneal lymph node metastasis. Cholecystectomy was performed. Primary hepatoid adenocarcinoma of the gallbladder was confirmed by histopathology.
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http://dx.doi.org/10.1097/RLU.0000000000003259DOI Listing
November 2020

Multiple Cutaneous Leiomyomas Showing Increased FDG Uptake.

Clin Nucl Med 2020 Oct;45(10):827-829

Nuclear Medicine, Changhai Hospital, Navy Military Medical University, Shanghai, China.

Cutaneous leiomyomas are rare, sporadic, or inherited benign tumors arising from smooth muscle cells of the skin associated with various disorders. We present a case of multiple cutaneous leiomyomas showing increased FDG uptake with SUVmax of 19.9. This case indicates cutaneous leiomyoma should be considered as a rare differential diagnosis in patients with hypermetabolic cutaneous lesions. Careful correlation with clinical history is needed to avoid misdiagnosis.
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http://dx.doi.org/10.1097/RLU.0000000000003213DOI Listing
October 2020

Dual-Phase 99mTc-MIBI SPECT/CT in the Characterization of Enhancing Solid Renal Tumors: A Single-Institution Study of 147 Cases.

Clin Nucl Med 2020 Oct;45(10):765-770

From the Departments of Nuclear Medicine.

Purpose: The aim of this study was to investigate the value of dual-phase Tc-MIBI SPECT/CT in the differential diagnosis between benign and malignant enhancing solid renal tumors.

Patients And Methods: Totally, 180 patients were imaged with dual-phase Tc-MIBI SPECT/CT, which was performed 30 minutes and 90 minutes after Tc-MIBI administration. Among them, 147 patients with 148 histologically proved solid renal tumors met the selection criteria and were included for the final analysis. Relative quantification was performed by measuring the radioactive uptake ratio of tumor to the normal renal parenchymal background for both early and delayed images.

Results: Benign renal tumors (4 renal oncocytomas and 8 lipid-poor angiomyolipomas) demonstrated a significantly higher early relative uptake value (ERUV) and delayed relative uptake value (DRUV) than malignant renal tumors (n = 136; both P < 0.0001). The ERUV cutoff value of 0.53 helped to differentiate benign from malignant renal tumors, with sensitivity of 100%, specificity of 94.8%, and accuracy of 95.3% for the diagnosis of benign renal tumors. The DRUV cutoff value of 0.50 helped to differentiate benign from malignant renal tumors, with sensitivity of 100%, specificity of 96.3%, and accuracy of 96.6% for the diagnosis of benign renal tumors. There was no statistically significant difference between the efficacy of ERUV and DRUV in the differential diagnosis between benign and malignant renal tumors (P = 0.5). The efficacies of ERUV and DRUV were all significantly higher than the retention index (both P < 0.0001).

Conclusions: Both early and delayed phase Tc-MIBI SPECT/CT are helpful for distinguishing benign renal oncocytoma and lipid-poor angiomyolipoma from malignant renal tumors, and the delayed phase imaging tends to show higher diagnostic accuracy.
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http://dx.doi.org/10.1097/RLU.0000000000003212DOI Listing
October 2020

Thymic Granuloma Mimicking Malignancy on 18F-FDG PET/CT.

Clin Nucl Med 2020 May;45(5):398-400

Department of Pathology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

We present a case with an unexpected nodule in the thymus showing increased F-FDG uptake on PET/CT. The nodule was surgically removed. Histopathologic examination revealed granuloma in the thymus. This case indicates physicians and radiologists must be aware that although thymic granuloma is rare, it should be included in the differential diagnosis of the thymic lesions with F-FDG accumulation along with neoplastic and nonneoplastic conditions.
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http://dx.doi.org/10.1097/RLU.0000000000002971DOI Listing
May 2020

Isolated Pancreatic Metastasis From Squamous Cell Lung Cancer Mimicking Primary Pancreatic Ductal Adenocarcinoma on FDG PET/CT.

Clin Nucl Med 2020 May;45(5):420-422

Department of Nuclear Medicine, Changhai Hospital, Navy Military Medical University, Shanghai, China.

Isolated pancreatic metastasis from lung cancer is rare. We present a case of isolated pancreatic metastasis from squamous cell lung cancer. The pancreatic tumor showed hypovascularity on enhanced MRI and intense FDG uptake on FDG PET/CT mimicking primary pancreatic ductal adenocarcinoma. This case indicates pancreatic metastasis should be considered as a differential diagnosis in patients with a history of extrapancreatic cancer and hypermetabolic pancreatic lesion.
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http://dx.doi.org/10.1097/RLU.0000000000002986DOI Listing
May 2020

18F-FDG PET/CT and 68Ga-DOTATOC PET/CT in Diffuse Pancreatic Neuroendocrine Tumor.

Clin Nucl Med 2020 May;45(5):e245-e248

Department of Nuclear Medicine, Changhai Hospital.

We present 2 cases of pancreatic neuroendocrine tumor with diffuse involvement of the entire pancreas. One case with G2 pancreatic neuroendocrine tumor showed nearly normal pancreatic shape and signal intensity on MRI, normal pancreatic FDG uptake, and diffuse pancreatic Ga-DOTATOC uptake. The other case with G3 pancreatic neuroendocrine tumor showed diffusely enlarged pancreas with abnormal MR signal intensity and increased FDG uptake. These 2 cases indicate that neuroendocrine tumor should be included in the differential diagnosis of diffuse pancreatic diseases. Somatostatin receptor imaging may be helpful for the diagnosis of diffuse pancreatic neuroendocrine tumor in equivocal cases.
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http://dx.doi.org/10.1097/RLU.0000000000002962DOI Listing
May 2020

Infected Mediastinal Bronchogenic Cyst Mimicking Malignancy on FDG PET/CT.

Clin Nucl Med 2020 Feb;45(2):172-173

Department of Nuclear Medicine, Changhai Hospital, Second Military Medical University, Shanghai, China.

A 51-year-old man presented with cough and pain in his upper chest for 1 week. Chest CT showed an ill-defined right paratracheal mass with slight enhancement in the upper mediastinum. A FDG PET/CT was performed showing focal increased FDG uptake with SUVmax of 4.7 in the mass. The mass was excised surgically. Histopathologic examination revealed infected bronchogenic cyst.
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http://dx.doi.org/10.1097/RLU.0000000000002860DOI Listing
February 2020

Increased FDG Uptake in the Center of the Gallbladder Stone: An Enigma.

Authors:
Xia Ji Aisheng Dong

Clin Nucl Med 2019 Dec;44(12):985-986

Department of Nuclear Medicine, Changhai Hospital, Second Military Medical University, Shanghai, China.

We present a case with a large gallbladder stone showing central hypermetabolism detected incidentally by an FDG PET/CT scan. However, the same gallbladder stone did not showed any FDG activity on the FDG PET/CT scan performed 2 years ago. The mechanism of variable FDG uptake in the same gallbladder stone is unclear, which needs further investigation.
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http://dx.doi.org/10.1097/RLU.0000000000002769DOI Listing
December 2019

Incidental Primary Breast Lymphoma on 99mTc-Sestamibi Myocardial Perfusion Imaging With SPECT/CT.

Clin Nucl Med 2019 Aug;44(8):e492-e494

Department of PET Center, Xiangya Hospital, Central South University, Changsha, China.

We present a 53-year-old woman who had shortness of breath and atypical chest pain and underwent Tc-sestamibi myocardial perfusion imaging to detect coronary artery disease. The raw data in cine format showed an incidental focus close to the heart, and SPECT/CT fused images revealed a focus of intense uptake in the left breast. The subsequent histopathologic findings and F-FDG PET/CT imaging confirmed the diagnosis as primary breast lymphoma. After 3 cycles of chemotherapy, previously visualized abnormal uptake in the left breast disappeared on the follow-up PET/CT.
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http://dx.doi.org/10.1097/RLU.0000000000002572DOI Listing
August 2019

FDG PET/CT in a Case of Primary Pulmonary Ewing Sarcoma.

Clin Nucl Med 2019 Aug;44(8):666-668

Department of Pathology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.

Extraskeletal Ewing sarcoma is rare. The common locations of extraskeletal Ewing sarcoma include the paravertebral region, lower extremities, and chest wall. Primary pulmonary Ewing sarcoma is extremely rare. Because Ewing sarcoma is sensitive to specialized chemotherapy regimens, accurate diagnosis is therefore critical. The diagnosis of pulmonary Ewing sarcoma can be challenging and need immunohistochemical and cytogenetic analyses. Imaging findings of pulmonary Ewing sarcoma have been rarely reported. This report describes a case of primary pulmonary Ewing sarcoma with immunohistochemical, cytogenetic, CT, and FDG PET/CT findings.
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http://dx.doi.org/10.1097/RLU.0000000000002659DOI Listing
August 2019

FDG PET/CT in a Case of Bilateral Tuberculous Epididymo-orchitis.

Clin Nucl Med 2019 Sep;44(9):757-760

Department of Nuclear Medicine, Changhai Hospital, Second Military Medical University, Shanghai, China.

Isolated genital tuberculosis is rare. We present a case of bilateral tuberculous epididymo-orchitis showing high FDG uptake on FDG PET/CT. In addition, the patient had a prostatic FDG-avid lesion, consistent with tuberculous prostatitis. This case indicates tuberculous epididymo-orchitis, especially in tuberculosis-endemic regions, should be considered as a differential diagnosis in patients with hypermetabolic epididymal or testicular lesions, including benign and malignant tumors, bacterial epididymo-orchitis, abscess, idiopathic granulomatous orchitis, and sarcoidosis.
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http://dx.doi.org/10.1097/RLU.0000000000002606DOI Listing
September 2019

Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome-Associated Renal Cell Carcinoma Showing High FDG Uptake.

Clin Nucl Med 2019 May;44(5):420-423

Department of Pathology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome is a rare autosomal-dominant disease, characterized by the development of cutaneous and uterine leiomyomas and renal cell carcinoma (RCC). Approximately 20% to 30% of patients with HLRCC syndrome develop RCC resembling sporadic type 2 papillary RCC, which is aggressive and associated with a poor prognosis. Information on the clinical usefulness of FDG PET/CT in HLRCC syndrome-associated RCC is limited. We present a case of HLRCC syndrome-associated RCC showing high FDG uptake in both the primary RCC and retroperitoneal lymph node metastases. In addition, the patient had 2 hypermetabolic uterine leiomyomas.
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http://dx.doi.org/10.1097/RLU.0000000000002495DOI Listing
May 2019

Focal Myositis of the Leg Presenting as Fever of Unknown Origin Detected by FDG PET/CT.

Clin Nucl Med 2019 Mar;44(3):251-254

Department of Pathology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Focal myositis is an uncommon inflammatory pseudotumor of the skeletal muscle that may mimic neoplastic and inflammatory diseases. We present one case of focal myositis involving the left proximal vastus lateralis and vastus intermedius, and left soleus showing intense FDG uptake on FDG PET/CT. This case indicates that focal myositis should be considered as a differential diagnosis in patients with focal hypermetabolic muscular lesions, including benign and malignant tumors, necrotizing autoimmune myopathy, nodular fasciitis, myositis ossificans, and muscular sarcoidosis.
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http://dx.doi.org/10.1097/RLU.0000000000002427DOI Listing
March 2019

Diffuse cavitary benign metastasising leiomyoma of the lung.

Thorax 2019 02 15;74(2):208-209. Epub 2018 Dec 15.

Department of Pathology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

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http://dx.doi.org/10.1136/thoraxjnl-2018-212769DOI Listing
February 2019

FDG PET/CT in a Case of Dural Amyloidoma.

Clin Nucl Med 2018 Dec;43(12):925-929

Department of Nuclear Medicine, Changhai Hospital, Second Military Medical University, Shanghai, China.

Dural amyloidoma is an unusual presentation of central nervous system amyloidosis. A 49-year-old woman presented with 1-month history of repeated episodes of vertigo. Precontrast MRI showed dural thickening over right frontal convexity with signal intensity similar to white matter. Postcontrast T1-weighted images showed remarkable enhancement of the lesion. Dural amyloidoma was confirmed by partial resection of the lesion. The patient underwent no further treatment. A follow-up FDG PET/CT showed increased FDG uptake of the residual dural amyloidoma. This case indicates dural amyloidoma should be included in the differential diagnosis of abnormal FDG uptake in dural lesions.
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http://dx.doi.org/10.1097/RLU.0000000000002304DOI Listing
December 2018

FDG PET/CT in a Case of Human African Trypanosomiasis (Sleeping Sickness).

Clin Nucl Med 2018 Aug;43(8):619-622

Department of Pathology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Human African trypanosomiasis imported to nonendemic countries is rare. It is very difficult to establish the correct diagnosis of human African trypanosomiasis in nonendemic areas. We present a case of human African trypanosomiasis with MRI and FDG PET/CT findings. Head MRI showed hyperintense areas in bilateral internal capsules. Abdominal and pelvic MRI showed hepatosplenomegaly and multiple enlarged lymph nodes. FDG PET/CT showed generalized hypermetabolic lymph nodes, diffuse FDG uptake of the spleen, and hepatosplenomegaly mimicking lymphoma. In addition, FDG PET/CT revealed decreased FDG uptake in the medial occipital cortex and cardiomegaly with pericardial effusion.
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http://dx.doi.org/10.1097/RLU.0000000000002149DOI Listing
August 2018

Increased FDG Uptake in a Giant Bone Island Mimicking Malignancy.

Clin Nucl Med 2018 Jun;43(6):e209-e211

Histologically proven bone islands exhibiting increased FDG uptake have been rarely reported before. We present a case with active giant bone island in the left humerus showing increased FDG uptake with SUVmax of 3.8. The diagnosis was confirmed by open biopsy and follow-up. Increased osteoblastic activity, proliferating and active fibroblasts, and increased blood flow may contribute to the increased FDG uptake of this giant bone island. This case indicates bone island should be included in the differential diagnosis of abnormal FDG uptake in focal sclerotic bone lesions, especially in patients with known malignancy.
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http://dx.doi.org/10.1097/RLU.0000000000002095DOI Listing
June 2018

Pedunculated Hepatocellular Carcinoma Mimicking Right Adrenal Tumor on FDG PET/CT.

Clin Nucl Med 2018 Jul;43(7):e242-e244

Department of Pathology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.

Pedunculated hepatocellular carcinoma is an unusual form of hepatocellular carcinoma protruding from the liver with or without a pedicle. We present a case of pedunculated hepatocellular carcinoma misdiagnosed as right adrenal tumor on MRI and FDG PET/CT. Intraoperative exploration revealed the mass was attached to the liver, but the right adrenal gland was intact. Laparoscopic biopsy revealed poorly differentiated hepatocellular carcinoma. This case indicates it may be difficult to diagnose pedunculated hepatocellular carcinoma because it is hard to define its origin on imaging. Elevated alpha-fetoprotein level and a history of viral hepatitis may be helpful for the diagnosis.
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http://dx.doi.org/10.1097/RLU.0000000000002096DOI Listing
July 2018

FDG PET/CT in 2 Cases of Hepatic Pseudolymphoma.

Clin Nucl Med 2018 May;43(5):e166-e169

Hepatic pseudolymphoma, also known as reactive lymphoid hyperplasia or nodular lymphoid hyperplasia, is a rare benign lymphoproliferative lesion. Preoperative diagnosis of hepatic pseudolymphoma is challenging. We present 2 cases of hepatic pseudolymphoma with focal intense FDG uptake on FDG PET/CT mimicking malignancy. These 2 cases suggest that hepatic pseudolymphoma should be considered as a rare differential diagnosis in patients with focal hypermetabolic hepatic lesion.
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http://dx.doi.org/10.1097/RLU.0000000000002053DOI Listing
May 2018

Castleman's Disease of the Kidney Mimicking Renal Cell Carcinoma on FDG PET/CT.

Clin Nucl Med 2018 May;43(5):e160-e163

Castleman's disease of the kidney is extremely rare. We present a case of Castleman's disease in the left kidney with multiple para-aortic enlarged lymph nodes. Both the renal lesion and para-aortic lymph nodes showed hypervascularity on enhanced CT and minimally increased FDG uptake on FDG PET/CT, mimicking renal cell carcinoma with para-aortic nodal metastases. This case suggests that Castleman's disease should be considered as a rare differential diagnosis in patients with a hypervascular and hypermetabolic renal lesion.
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http://dx.doi.org/10.1097/RLU.0000000000001995DOI Listing
May 2018

FDG PET/CT in Immunoglobulin G4-Related Spinal Hypertrophic Pachymeningitis.

Clin Nucl Med 2017 Dec;42(12):958-961

From the *Department of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia; and Departments of †Nuclear Medicine, ‡Orthopaedic Surgery, and §Pathology, Changhai Hospital, Second Military Medical University, Shanghai, China.

A 49-year-old woman complained of right upper back pain for 1 month. Serum tests showed increased erythrocyte sedimentation rate. Thoracic spinal MRI showed an epidural lesion at the T1-T4 level with inhomogeneous signal intensity on T2-weighted images, slightly higher signal intensity than spinal cord on T1-weighted images, and remarkable enhancement on enhanced T1-weighted images. Epidural malignant tumor was suspected. FDG PET/CT was performed showing increased FDG uptake of the lesion extending to the right T1-T2 and T2-T3 neural foramina. A decompressive posterior thoracic laminectomy with the lesion resection was performed. Immunoglobulin G4-related spinal hypertrophic pachymeningitis was confirmed by pathology.
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http://dx.doi.org/10.1097/RLU.0000000000001872DOI Listing
December 2017

FDG PET/CT in 2 Cases of Renal Metastasis From Esophageal Squamous Cell Carcinoma.

Clin Nucl Med 2017 Nov;42(11):896-898

From the *Department of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia; and Departments of †Nuclear Medicine, ‡Urology, and §Pathology, Changhai Hospital, Second Military Medical University, Shanghai, China.

Clinically, renal metastasis from esophageal squamous cell carcinoma is uncommon. We present 2 cases of renal metastasis from esophageal squamous cell carcinoma with enhanced CT and FDG PET/CT findings. In the first case, right kidney and right renal hilum were the only known metastatic sites. In the second case, bilateral kidneys were the only known metastatic sites. All the renal metastatic tumors appeared as hypovascular and hypoattenuating masses involving both the renal cortex and medulla on enhanced CT and intense FDG uptake on FDG PET/CT.
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http://dx.doi.org/10.1097/RLU.0000000000001813DOI Listing
November 2017
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