Publications by authors named "Ainhoa Arina"

43Publications

Cytoreduction and the Optimization Of Immune Checkpoint Inhibition with Radiation Therapy.

Int J Radiat Oncol Biol Phys 2020 Sep;108(1):17-26

Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2019.12.033DOI Listing
September 2020

Radiotherapy and Immunotherapy for Cancer: From "Systemic" to "Multisite".

Clin Cancer Res 2020 Jun 11;26(12):2777-2782. Epub 2020 Feb 11.

Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-2034DOI Listing
June 2020

Tumor-reprogrammed resident T cells resist radiation to control tumors.

Nat Commun 2019 09 2;10(1):3959. Epub 2019 Sep 2.

Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL, 60637, USA.

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http://dx.doi.org/10.1038/s41467-019-11906-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718618PMC
September 2019

Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy.

Immunity 2018 09 28;49(3):490-503.e4. Epub 2018 Aug 28.

Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75235-9072, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775781PMC
September 2018

Safety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors.

J Clin Oncol 2018 06 13;36(16):1611-1618. Epub 2018 Feb 13.

Jason J. Luke, Jeffrey M. Lemons, Theodore G. Karrison, Sean P. Pitroda, James M. Melotek, Yuanyuan Zha, Hania A. Al-Hallaq, Ainhoa Arina, Nikolai N. Khodarev, Linda Janisch, Paul Chang, Jyoti D. Patel, Gini F. Fleming, John Moroney, Manish R. Sharma, Mark J. Ratain, Thomas F. Gajewski, Ralph R. Weichselbaum, and Steven J. Chmura, The University of Chicago, Chicago, IL; Julia R. White, The Ohio State University, Columbus, OH.

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http://dx.doi.org/10.1200/JCO.2017.76.2229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978468PMC
June 2018

Tumor relapse prevented by combining adoptive T cell therapy with Salmonella typhimurium.

Oncoimmunology 2016 Jun 18;5(6):e1130207. Epub 2016 Feb 18.

Committee on Cancer Biology, University of Chicago, Chicago, IL, USA; Department of Pathology, University of Chicago, Chicago, IL, USA; Committee on Immunology, The University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1080/2162402X.2015.1130207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938310PMC
June 2016

Tumor-associated fibroblasts predominantly come from local and not circulating precursors.

Proc Natl Acad Sci U S A 2016 07 17;113(27):7551-6. Epub 2016 Jun 17.

Department of Pathology, The University of Chicago, Chicago, IL 60637; Committee on Immunology, The University of Chicago, Chicago, IL 60637; Committee on Cancer Biology, The University of Chicago, Chicago, IL 60637.

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http://dx.doi.org/10.1073/pnas.1600363113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941507PMC
July 2016

Enhancing T cell therapy by overcoming the immunosuppressive tumor microenvironment.

Semin Immunol 2016 02 10;28(1):54-63. Epub 2016 Feb 10.

Verona University Hospital and Department of Medicine, Verona 37134, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.smim.2016.01.002DOI Listing
February 2016

Myeloid-derived suppressor cell impact on endogenous and adoptively transferred T cells.

Curr Opin Immunol 2015 Apr 27;33:120-5. Epub 2015 Feb 27.

Verona University Hospital, Department of Pathology and Diagnostics, 37134 Verona, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2015.02.006DOI Listing
April 2015

Rethinking the role of myeloid-derived suppressor cells in adoptive T-cell therapy for cancer.

Authors:
Ainhoa Arina

Oncoimmunology 2014 15;3:e28464. Epub 2014 Apr 15.

Department of Pathology; The University of Chicago; Chicago, IL USA.

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http://dx.doi.org/10.4161/onci.28464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063155PMC
April 2014

Antigen-specific bacterial vaccine combined with anti-PD-L1 rescues dysfunctional endogenous T cells to reject long-established cancer.

Cancer Immunol Res 2013 Aug;1(2):123-33

Committee on Cancer Biology, The University of Chicago, Chicago, IL 60637 ; Department of Pathology, The University of Chicago, Chicago, IL 60637 ; Committee on Immunology, The University of Chicago, Chicago, IL 60637.

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http://dx.doi.org/10.1158/2326-6066.CIR-13-0058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895468PMC
August 2013

Immunotherapy and immunoescape in colorectal cancer.

World J Gastroenterol 2007 Nov;13(44):5822-31

Liver Unit, Facutad de Ciencias Biomédicas, Universidad Austral, Av Presidente Péron 1500, (1635) Derqui-Pilar, Buenos Aires, Argentina.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205429PMC
http://dx.doi.org/10.3748/wjg.v13.i44.5822DOI Listing
November 2007

Bone-marrow-derived cell differentiation into microglia: a study in a progressive mouse model of Parkinson's disease.

Neurobiol Dis 2007 Dec 7;28(3):316-25. Epub 2007 Aug 7.

Laboratory of Neurobiology and Experimental Neurology, Department of Physiology, Faculty of Medicine, University of La Laguna, La Laguna, Tenerife, Canary Islands, Spain.

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http://dx.doi.org/10.1016/j.nbd.2007.07.024DOI Listing
December 2007

Cellular liaisons of natural killer lymphocytes in immunology and immunotherapy of cancer.

Expert Opin Biol Ther 2007 May;7(5):599-615

University of Navarra, Centro de Investigación Médica Aplicada and Clinica Universitaria, Gene Therapy Unit, Avda. Pio XII 55, 31008, Pamplona, Spain.

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http://dx.doi.org/10.1517/14712598.7.5.599DOI Listing
May 2007

Immunogenic cell death and cross-priming are reaching the clinical immunotherapy arena.

Clin Cancer Res 2006 Apr;12(8):2385-9

Centro de Investigación Médica Aplicada, Clínica Universitaria and School of Medicine, University of Navarra, Pamplona, Spain.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-06-0314DOI Listing
April 2006

Low surface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma.

Cancer Res 2006 Feb;66(4):2442-50

Gene Therapy Unit, Department of Medicine, Centro de Investigación Médica Aplicada and Clínica Universitaria, University of Navarra School of Medicine, Pamplona, Spain.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-1681DOI Listing
February 2006

The many sounds of T lymphocyte silence.

Immunol Res 2005 ;33(2):135-47

Department of Medicine, CIMA and Clinica Universitaria, University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1385/IR:33:2:135DOI Listing
January 2006

Enhancement of CD4 and CD8 immunity by anti-CD137 (4-1BB) monoclonal antibodies during hepatitis C vaccination with recombinant adenovirus.

Vaccine 2005 May;23(27):3493-9

Division of Hepatology and Gene Therapy, University Clinic, Faculty of Medicine, Center for Applied Medical Research (CIMA), University of Navarra, Pio XII 55, 31008 Pamplona, Spain.

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http://dx.doi.org/10.1016/j.vaccine.2005.02.003DOI Listing
May 2005

Dendritic cells delivered inside human carcinomas are sequestered by interleukin-8.

Int J Cancer 2005 Aug;116(2):275-81

Division of Hepatology and Gene Therapy, Clínica Universitaria/School of Medicine, Foundation for Applied Medical Research, Universidad de Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1002/ijc.21046DOI Listing
August 2005

Intratumoural administration of dendritic cells: hostile environment and help by gene therapy.

Expert Opin Biol Ther 2005 Jan;5(1):7-22

University of Navarra School of Medicine, Gene Therapy Unit, Centro Investigación Médica Aplicada (CIMA), Avda/Pio XII,55, 31080 Pamplona, Spain.

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http://dx.doi.org/10.1517/14712598.5.1.7DOI Listing
January 2005

Improving efficacy of interleukin-12-transfected dendritic cells injected into murine colon cancer with anti-CD137 monoclonal antibodies and alloantigens.

Int J Cancer 2004 May;110(1):51-60

Gene Therapy Division, Fundación para la Investigación Médica Aplicada, University of Navarre, Irunlarrea s/n 31008 Pamplona, Navarre, Spain.

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http://dx.doi.org/10.1002/ijc.20093DOI Listing
May 2004

Potentiation of therapeutic immune responses against malignancies with monoclonal antibodies.

Clin Cancer Res 2003 Nov;9(15):5454-64

Centro de Investigación Médica aplicada and Clínica Universitaria, Universidad de Navarra, Pamplona, Spain.

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November 2003

Hepatitis C virus structural proteins impair dendritic cell maturation and inhibit in vivo induction of cellular immune responses.

J Virol 2003 Oct;77(20):10862-71

Division of Hepatology and Gene Therapy, Fundación para la Investigación Médica Aplicada (FIMA), University of Navarra, 31008 Pamplona, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC224971PMC
http://dx.doi.org/10.1128/jvi.77.20.10862-10871.2003DOI Listing
October 2003

Anti-ICAM-2 monoclonal antibody synergizes with intratumor gene transfer of interleukin-12 inhibiting activation-induced T-cell death.

Clin Cancer Res 2003 Sep;9(10 Pt 1):3546-54

Centro de Investigación Médica Aplicada (CIMA), Facultad de Medicina, Gene Therapy Unit, Universidad de Navarra, 31008 Pamplona, Spain.

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September 2003

Clinical implications of antigen transfer mechanisms from malignant to dendritic cells. exploiting cross-priming.

Exp Hematol 2002 Dec;30(12):1355-64

Centro de Investigación Médica Aplicada (CIMA), School of Medicine and Cell Therapy Area (Clínica Universitaria), University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1016/s0301-472x(02)00956-6DOI Listing
December 2002

Effective tumor immunotherapy: start the engine, release the brakes, step on the gas pedal,...and get ready to face autoimmunity.

Arch Immunol Ther Exp (Warsz) 2002 ;50(1):13-8

Gene Therapy Division, Facultad de Medicina and Clinica Universitaria, Universidad de Navarra, Pamplona, Spain.

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October 2002