Publications by authors named "Ailing Wan"

2 Publications

  • Page 1 of 1

Rational drug use analysis of antibiotics in surgical operation with nursing intervention.

Pak J Pharm Sci 2018 Sep;31(5(Special)):2263-2269

Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Rational use of antibiotics is an important part of clinical pharmacy in hospitals. In this paper, we compared and analyzed the use of antibiotics in 2016 and 2017, and put forward corresponding interventions. The results showed that the irrational use of drugs after the intervention was significantly reduced (p<0.05). The antibacterials used before the intervention was mainly cephalosporins (45.4%) and quinolones (26.2%). The antibiotics used after intervention was mainly cephalosporins (77.9%) and clindamycin (11.6%). There is no significant difference in the incidence of SSI in combination with a selection of appropriate antimicrobial agents and a variety of antibiotics and an irrational combination of drugs will increase the incidence of adverse drug reactions. Through the implementation of various intervention measures, the clinicians' awareness of the rational application of antimicrobial drugs has been improved significantly, and the rationality of drug use indications, medication course, drug selection, sample delivery rate and so on have been improved to varying degrees.
View Article and Find Full Text PDF

Download full-text PDF

Source
September 2018

ICAM-1 gene rs5498 polymorphism decreases the risk of coronary artery disease.

Medicine (Baltimore) 2018 Oct;97(40):e12523

Department of Emergency, the Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Background: Many studies investigated the association between intercellular adhesion molecule 1 (ICAM-1) gene rs5498 polymorphism and the risk of coronary artery disease (CAD). However, the results were inconsistent.

Methods: To clarify convincing association, we conducted a comprehensive meta-analysis by searching in PubMed, Embase, Web of sciences, Sciences citation index, Google scholar, Cochrane Library, and the CNKI databases. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated.

Results: A total of 29 case-control studies with 5,494 cases and 6,364 controls for rs5498 polymorphism were included. The studied populations of this meta-analysis included Caucasians and Asians. Meta-analysis showed that rs5498 polymorphism was associated with the decreased risk of CAD. Stratification analysis of ethnicity found that rs5498 polymorphism decreased the risk of CAD among Caucasians, but not among Asians. Stratification by type of CAD revealed that ICAM-1 gene rs5498 polymorphism was also correlated with the decreased risk of myocardial infarction (MI).

Conclusion: In conclusion, this meta-analysis indicates that ICAM-1 gene rs5498 polymorphism decreases the risk of CAD.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000012523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200538PMC
October 2018
-->