Publications by authors named "Ai Ni"

94Publications

A Clinical Genomics-Guided Prioritizing Strategy Enables Selecting Proper Cancer Cell Lines for Biomedical Research.

iScience 2020 Nov 28;23(11):101748. Epub 2020 Oct 28.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.

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http://dx.doi.org/10.1016/j.isci.2020.101748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662851PMC
November 2020

Regional variations of jaw bone characteristics in an ovariectomized rat model.

J Mech Behav Biomed Mater 2020 10 29;110:103952. Epub 2020 Jun 29.

Division of Orthodontics, College of Dentistry, The Ohio State University, Columbus, OH, 43210, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmbbm.2020.103952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509205PMC
October 2020

Variable Selection for Time-to-Event Data.

Authors:
Ai Ni Chi Song

Methods Mol Biol 2021 ;2194:61-76

Division of Biostatistics, College of Public Health, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1007/978-1-0716-0849-4_5DOI Listing
January 2021

scCATCH: Automatic Annotation on Cell Types of Clusters from Single-Cell RNA Sequencing Data.

iScience 2020 Mar 4;23(3):100882. Epub 2020 Feb 4.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2020.100882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031312PMC
March 2020

Prediction of Adverse Drug Reactions by Combining Biomedical Tripartite Network and Graph Representation Model.

Chem Res Toxicol 2020 01 13;33(1):202-210. Epub 2019 Dec 13.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences , Zhejiang University , Hangzhou 310058 , China.

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http://dx.doi.org/10.1021/acs.chemrestox.9b00238DOI Listing
January 2020

Copy number variation is highly correlated with differential gene expression: a pan-cancer study.

BMC Med Genet 2019 11 9;20(1):175. Epub 2019 Nov 9.

College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.

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http://dx.doi.org/10.1186/s12881-019-0909-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842483PMC
November 2019

Estimating Additive Interaction Effect in Stratified Two-Phase Case-Control Design.

Hum Hered 2019 21;84(2):90-108. Epub 2019 Oct 21.

Department of Biostatistics and Epidemiology, School of Public Health, Rutgers University, Piscataway, New York, USA.

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https://www.karger.com/Article/FullText/502738
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http://dx.doi.org/10.1159/000502738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925975PMC
May 2020

Incidence of infectious complications with the combination of bendamustine and an anti-CD20 monoclonal antibody

Leuk Lymphoma 2020 02 11;61(2):364-369. Epub 2019 Oct 11.

Lymphoma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1080/10428194.2019.1666378DOI Listing
February 2020

Prognostic value of baseline metabolic tumor volume measured on F-fluorodeoxyglucose positron emission tomography/computed tomography in melanoma patients treated with ipilimumab therapy.

Eur J Nucl Med Mol Imaging 2019 Apr 28;46(4):930-939. Epub 2018 Nov 28.

Molecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.

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http://dx.doi.org/10.1007/s00259-018-4211-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451667PMC
April 2019

Tuning Parameter Selection in Cox Proportional Hazards Model with a Diverging Number of Parameters.

Authors:
Ai Ni Jianwen Cai

Scand Stat Theory Appl 2018 Sep 16;45(3):557-570. Epub 2018 Jan 16.

Department of Biostatistics, University of North Carolina at Chapel Hill.

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http://doi.wiley.com/10.1111/sjos.12313
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http://dx.doi.org/10.1111/sjos.12313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107315PMC
September 2018

Network pharmacology study reveals energy metabolism and apoptosis pathways-mediated cardioprotective effects of Shenqi Fuzheng.

J Ethnopharmacol 2018 Dec 23;227:155-165. Epub 2018 Aug 23.

Department of TCM Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, Zhejiang, China. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2018.08.029DOI Listing
December 2018

Virtual Screening and Experimental Testing of B1 Metallo-β-lactamase Inhibitors.

J Chem Inf Model 2018 09 29;58(9):1902-1914. Epub 2018 Aug 29.

Department of Pharmaceutical Sciences, College of Pharmacy , Western University of Health Sciences , Pomona , California 91766-1854 , United States.

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http://dx.doi.org/10.1021/acs.jcim.8b00133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527342PMC
September 2018

Ado-Trastuzumab Emtansine for Patients With HER2-Mutant Lung Cancers: Results From a Phase II Basket Trial.

J Clin Oncol 2018 08 10;36(24):2532-2537. Epub 2018 Jul 10.

Bob T. Li, Ronglai Shen, Darren Buonocore, Zachary T. Olah, Ai Ni, Michelle S. Ginsberg, Gary A. Ulaner, Michael Offin, Daniel Feldman, Helen H. Won, Edyta B. Brzostowski, Gregory J. Riely, David B. Solit, David M. Hyman, Alexander Drilon, Charles M. Rudin, Michael F. Berger, Jose Baselga, Maurizio Scaltriti, Maria E. Arcila, and Mark G. Kris, Memorial Sloan Kettering Cancer Center, and Weill Cornell Medical College, New York, NY; Bob T. Li, Nick Pavlakis, and Stephen Clarke, Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia; and Todd Hembrough, Fabiola Cecchi, and Sarit Schwartz, NantOmics, Rockville, MD.

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http://ascopubs.org/doi/10.1200/JCO.2018.77.9777
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http://dx.doi.org/10.1200/JCO.2018.77.9777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366814PMC
August 2018

Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.

Cancer Cell 2018 05 12;33(5):843-852.e4. Epub 2018 Apr 12.

Department of Medicine, Memorial Sloan Kettering Cancer Center, 885 2(nd) Avenue, New York, NY 10017, USA; Weill Cornell School of Medicine, New York, NY, USA; Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Ludwig Collaborative Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15356108183012
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http://dx.doi.org/10.1016/j.ccell.2018.03.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953836PMC
May 2018

Molecular Determinants of Response to Anti-Programmed Cell Death (PD)-1 and Anti-Programmed Death-Ligand 1 (PD-L1) Blockade in Patients With Non-Small-Cell Lung Cancer Profiled With Targeted Next-Generation Sequencing.

J Clin Oncol 2018 03 16;36(7):633-641. Epub 2018 Jan 16.

Hira Rizvi, Francisco Sanchez-Vega, Konnor La, Walid Chatila, Philip Jonsson, Darragh Halpenny, Andrew Plodkowski, Niamh Long, Jennifer L. Sauter, Natasha Rekhtman, Travis Hollmann, Ronglai Shen, Ai Ni, Kathryn C. Arbour, Taha Merghoub, Jedd Wolchok, Jamie E. Chaft, Mark G. Kris, Charles M. Rudin, Nicholas D. Socci, Michael F. Berger, Barry S. Taylor, Ahmet Zehir, David B. Solit, Maria E. Arcila, Marc Ladanyi, Gregory J. Riely, Nikolaus Schultz, and Matthew D. Hellmann, Memorial Sloan Kettering Cancer Center; Taha Merghoub, Jedd Wolchok, Alexandra Snyder, Jamie E. Chaft, Mark G. Kris, Charles M. Rudin, Gregory J. Riely, and Matthew D. Hellmann, Weill Cornell Medical College, New York, NY; Kurt A. Schalper, Yale School of Medicine, New Haven, CT; Justin F. Gainor, Massachusetts General Hospital, Boston, MA; and Alexandra Snyder, Adaptive Biotechnologies, Seattle, WA.

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http://dx.doi.org/10.1200/JCO.2017.75.3384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075848PMC
March 2018

A multiple biomarker assay for quality assessment of botanical drugs using a versatile microfluidic chip.

Sci Rep 2017 09 25;7(1):12243. Epub 2017 Sep 25.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.

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http://dx.doi.org/10.1038/s41598-017-12453-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612938PMC
September 2017

Revealing topics and their evolution in biomedical literature using Bio-DTM: a case study of ginseng.

Chin Med 2017 12;12:27. Epub 2017 Sep 12.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058 China.

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http://dx.doi.org/10.1186/s13020-017-0148-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596940PMC
September 2017

Expression of PD-L1 and other immunotherapeutic targets in thymic epithelial tumors.

PLoS One 2017 3;12(8):e0182665. Epub 2017 Aug 3.

Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0182665PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542609PMC
August 2017

A regularized variable selection procedure in additive hazards model with stratified case-cohort design.

Authors:
Ai Ni Jianwen Cai

Lifetime Data Anal 2018 07 28;24(3):443-463. Epub 2017 Jul 28.

Department of Biostatistics, University of North Carolina at Chapel Hill, 135 Dauer Drive, Chapel Hill, NC, 27599, USA.

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http://link.springer.com/10.1007/s10985-017-9402-7
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http://dx.doi.org/10.1007/s10985-017-9402-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787409PMC
July 2018

In silico modeling on ADME properties of natural products: Classification models for blood-brain barrier permeability, its application to traditional Chinese medicine and in vitro experimental validation.

J Mol Graph Model 2017 08 7;75:347-354. Epub 2017 Jun 7.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, No. 866 Yuhangtang Road, Hangzhou, 310058, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10933263173024
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http://dx.doi.org/10.1016/j.jmgm.2017.05.021DOI Listing
August 2017

Prognostic impact of TTF-1 expression in patients with stage IV lung adenocarcinomas.

Lung Cancer 2017 06 28;108:205-211. Epub 2017 Mar 28.

Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, 300 E 66(th) St., New York, NY 10065, USA; Department of Medicine, Weill Cornell Medical College, 1300 York Ave., New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2017.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423973PMC
June 2017

A Bioactive Chemical Markers Based Strategy for Quality Assessment of Botanical Drugs: Xuesaitong Injection as a Case Study.

Sci Rep 2017 05 25;7(1):2410. Epub 2017 May 25.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.

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http://dx.doi.org/10.1038/s41598-017-02305-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445085PMC
May 2017

Deciphering chemical interactions between Glycyrrhizae Radix and Coptidis Rhizoma by liquid chromatography with transformed multiple reaction monitoring mass spectrometry.

J Sep Sci 2017 Mar 27;40(6):1254-1265. Epub 2017 Feb 27.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.

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http://doi.wiley.com/10.1002/jssc.201601054
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http://dx.doi.org/10.1002/jssc.201601054DOI Listing
March 2017

Niclosamide is a Negative Allosteric Modulator of Group I Metabotropic Glutamate Receptors: Implications for Neuropathic Pain.

Pharm Res 2016 12 8;33(12):3044-3056. Epub 2016 Sep 8.

Department of Pharmacology, Rutgers-Robert Wood Johnson Medical School, Rutgers University, 661 Hoes Lane West, Staged Research Building (room SRB-124), Piscataway, New Jersey, 08854, USA.

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http://dx.doi.org/10.1007/s11095-016-2027-9DOI Listing
December 2016

CNARA: reliability assessment for genomic copy number profiles.

BMC Genomics 2016 10 12;17(1):799. Epub 2016 Oct 12.

Institute of Molecular Life Sciences and Swiss Institute of Bioinformatics, University of Zurich, Winterthurerstrasse 190, Zurich, CH-8057, Switzerland.

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http://dx.doi.org/10.1186/s12864-016-3074-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062840PMC
October 2016

Network-based Assessment on Chemical-induced Cholestatic Liver Injury.

Curr Top Med Chem 2016 ;16(30):3668-3677

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China..

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http://dx.doi.org/10.2174/1568026616666160721095647DOI Listing
February 2017

Exploring the interaction between Salvia miltiorrhiza and human serum albumin: Insights from herb-drug interaction reports, computational analysis and experimental studies.

Spectrochim Acta A Mol Biomol Spectrosc 2016 May 23;161:1-7. Epub 2016 Feb 23.

Pharmaceutical Informatics Institute, College of Pharmaceutical Science, Zhejiang University, Hangzhou, Zhejiang, PR China.

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https://linkinghub.elsevier.com/retrieve/pii/S13861425163007
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http://dx.doi.org/10.1016/j.saa.2016.02.015DOI Listing
May 2016

[Toxicogenomics and its application in safety evaluation of traditional Chinese medicine].

Zhongguo Zhong Yao Za Zhi 2015 Jul;40(14):2690-5

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July 2015

Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA.

JAMA Oncol 2016 Jan;2(1):104-11

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York6Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering, New York, New York9Weill Cornell Medical College, New York, New York.

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http://dx.doi.org/10.1001/jamaoncol.2015.5208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477989PMC
January 2016

Transcriptomics: a sword to cut the Gordian knot of traditional Chinese medicine.

Biomark Med 2015 26;9(11):1201-13. Epub 2015 Oct 26.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.

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http://dx.doi.org/10.2217/bmm.15.91DOI Listing
August 2016

Elucidating the Role of Residue 67 in IMP-Type Metallo-β-Lactamase Evolution.

Antimicrob Agents Chemother 2015 Dec 14;59(12):7299-307. Epub 2015 Sep 14.

Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, California, USA

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http://aac.asm.org/content/59/12/7299.full.pdf
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http://aac.asm.org/content/early/2015/09/09/AAC.01651-15.ful
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http://aac.asm.org/lookup/doi/10.1128/AAC.01651-15
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http://dx.doi.org/10.1128/AAC.01651-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649200PMC
December 2015

Qualitative analysis of chemical constituents in traditional Chinese medicine analogous formula cheng-Qi decoctions by liquid chromatography-mass spectrometry.

Biomed Chromatogr 2016 Mar 4;30(3):301-11. Epub 2015 Sep 4.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.

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http://dx.doi.org/10.1002/bmc.3549DOI Listing
March 2016

Chemical and Metabolic Profiling of Si-Ni Decoction Analogous Formulae by High performance Liquid Chromatography-Mass Spectrometry.

Sci Rep 2015 Jun 29;5:11638. Epub 2015 Jun 29.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.

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http://dx.doi.org/10.1038/srep11638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484491PMC
June 2015

Fabrication of enzyme-immobilized halloysite nanotubes for affinity enrichment of lipase inhibitors from complex mixtures.

J Chromatogr A 2015 May 9;1392:20-7. Epub 2015 Mar 9.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2015.03.002DOI Listing
May 2015

In silico methods for predicting drug-drug interactions with cytochrome P-450s, transporters and beyond.

Adv Drug Deliv Rev 2015 Jun 19;86:46-60. Epub 2015 Mar 19.

Collaborations in Chemistry, 5616 Hilltop Needmore Road, Fuquay-Varina, NC 27526, USA. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2015.03.006DOI Listing
June 2015

Identification of Nitazoxanide as a Group I Metabotropic Glutamate Receptor Negative Modulator for the Treatment of Neuropathic Pain: An In Silico Drug Repositioning Study.

Pharm Res 2015 Aug 12;32(8):2798-807. Epub 2015 Mar 12.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, 310058, People' Republic of China.

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http://link.springer.com/content/pdf/10.1007/s11095-015-1665
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http://link.springer.com/10.1007/s11095-015-1665-7
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http://dx.doi.org/10.1007/s11095-015-1665-7DOI Listing
August 2015

Derivative multiple reaction monitoring and single herb calibration approach for multiple components quantification of traditional Chinese medicine analogous formulae.

J Chromatogr A 2015 Jan 12;1376:126-42. Epub 2014 Dec 12.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.

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http://dx.doi.org/10.1016/j.chroma.2014.12.024DOI Listing
January 2015

Rapid screening natural-origin lipase inhibitors from hypolipidemic decoctions by ultrafiltration combined with liquid chromatography-mass spectrometry.

J Pharm Biomed Anal 2015 Feb 18;104:67-74. Epub 2014 Nov 18.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2014.11.022DOI Listing
February 2015

arrayMap 2014: an updated cancer genome resource.

Nucleic Acids Res 2015 Jan 26;43(Database issue):D825-30. Epub 2014 Nov 26.

Institute of Molecular Life Sciences, University of Zurich, 8057 Zurich, Switzerland Swiss Institute of Bioinformatics, 8057 Zurich, Switzerland

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http://dx.doi.org/10.1093/nar/gku1123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383937PMC
January 2015

Novel virtual screening approach for the discovery of human tyrosinase inhibitors.

PLoS One 2014 26;9(11):e112788. Epub 2014 Nov 26.

Global R&D, AVON Products, Inc., Suffern, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112788PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245091PMC
July 2015

Dissecting active ingredients of Chinese medicine by content-weighted ingredient-target network.

Mol Biosyst 2014 Jul 30;10(7):1905-11. Epub 2014 Apr 30.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.

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http://dx.doi.org/10.1039/c3mb70581aDOI Listing
July 2014

Progenetix: 12 years of oncogenomic data curation.

Nucleic Acids Res 2014 Jan 12;42(Database issue):D1055-62. Epub 2013 Nov 12.

Institute of Molecular Life Sciences, University of Zürich, CH-8057 Zürich, Switzerland, Swiss Institute of Bioinformatics, University of Zürich, CH-8057 Zürich, Switzerland and Swiss Institute of Bioinformatics, University of Lausanne, CH-1015 Lausanne, Switzerland.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkt1108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965091PMC
January 2014

LTMap: a web server for assessing the potential liver toxicity by genome-wide transcriptional expression data.

J Appl Toxicol 2014 Jul 11;34(7):805-9. Epub 2013 Sep 11.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.

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http://doi.wiley.com/10.1002/jat.2923
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http://dx.doi.org/10.1002/jat.2923DOI Listing
July 2014

Relating anatomical therapeutic indications by the ensemble similarity of drug sets.

J Chem Inf Model 2013 Aug 12;53(8):2154-60. Epub 2013 Aug 12.

Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.

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http://dx.doi.org/10.1021/ci400155xDOI Listing
August 2013

Major burn injury is not associated with acute traumatic coagulopathy.

J Trauma Acute Care Surg 2013 Jun;74(6):1474-9

Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1097/TA.0b013e3182923193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342258PMC
June 2013

Pregnane X receptor mediates dyslipidemia induced by the HIV protease inhibitor amprenavir in mice.

Mol Pharmacol 2013 Jun 21;83(6):1190-9. Epub 2013 Mar 21.

Graduate Center for Nutritional Sciences, University of Kentucky, Lexington, KY, USA.

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http://dx.doi.org/10.1124/mol.113.085753DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657097PMC
June 2013

Potent inhibitors of human organic anion transporters 1 and 3 from clinical drug libraries: discovery and molecular characterization.

Mol Pharm 2012 Nov 25;9(11):3340-6. Epub 2012 Sep 25.

Department of Pharmaceutics, Rutgers, The State University of New Jersey Piscataway, New Jersey 08854, United States.

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http://dx.doi.org/10.1021/mp300365tDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490050PMC
November 2012

Sequential expression of IGF-IB followed by active TGF-β1 induces synergistic pulmonary fibroproliferation in vivo.

Am J Physiol Lung Cell Mol Physiol 2012 Nov 24;303(9):L788-98. Epub 2012 Aug 24.

Department of Critical Care Medicine, Faculty of Medicine, University of Calgary, Alberta, Canada.

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http://dx.doi.org/10.1152/ajplung.00008.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517679PMC
November 2012

Lack of androgenicity and estrogenicity of the three monomers used in Eastman's Tritan™ copolyesters.

Food Chem Toxicol 2012 Jun 17;50(6):2196-205. Epub 2012 Feb 17.

Science Strategies, LLC, Citizens Commonwealth Center, 300 Preston Ave, Suite 308, Charlottesville, VA 22902, USA.

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http://dx.doi.org/10.1016/j.fct.2012.02.010DOI Listing
June 2012

Bisphenol A and its analogues activate human pregnane X receptor.

Environ Health Perspect 2012 Mar 3;120(3):399-405. Epub 2012 Jan 3.

Graduate Center for Nutritional Sciences, University of Kentucky, Lexington, Kentucky 40536, USA.

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http://dx.doi.org/10.1289/ehp.1104426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295358PMC
March 2012

Evolution of promiscuous nuclear hormone receptors: LXR, FXR, VDR, PXR, and CAR.

Mol Cell Endocrinol 2011 Mar 6;334(1-2):39-48. Epub 2010 Jul 6.

Department of Pathology, University of Iowa Hospitals and Clinics, RCP 6233, 200 Hawkins Drive, Iowa City, IA 52242, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S03037207100035
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http://dx.doi.org/10.1016/j.mce.2010.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033471PMC
March 2011

Two farnesoid X receptor alpha isoforms in Japanese medaka (Oryzias latipes) are differentially activated in vitro.

Aquat Toxicol 2010 Jul 1;98(3):245-255. Epub 2010 Mar 1.

Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC 27695, USA. Electronic address:

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http://dx.doi.org/10.1016/j.aquatox.2010.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874645PMC
July 2010

Human ADA3 regulates RARalpha transcriptional activity through direct contact between LxxLL motifs and the receptor coactivator pocket.

Nucleic Acids Res 2010 Sep 22;38(16):5291-303. Epub 2010 Apr 22.

Department of Pharmacology, University of Medicine & Dentistry of New Jersey-Robert Wood Johnson Medical School, Piscataway, NJ 08854, New Jersey, USA.

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http://dx.doi.org/10.1093/nar/gkq269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938230PMC
September 2010

Evolving carbapenemases: can medicinal chemists advance one step ahead of the coming storm?

J Med Chem 2010 Apr;53(8):3013-27

Chemistry Department and Center for Macromolecular Modeling and Materials Design, California State Polytechnic University, Pomona, California, USA.

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http://dx.doi.org/10.1021/jm9012938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855403PMC
April 2010

Adenovirus-mediated gene transfer of hIGF-IB in mouse lungs induced prolonged inflammation but no fibroproliferation.

Am J Physiol Lung Cell Mol Physiol 2010 Apr 15;298(4):L492-500. Epub 2010 Jan 15.

Department of Physiology, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1152/ajplung.00310.2009DOI Listing
April 2010

Understanding nuclear receptors using computational methods.

Drug Discov Today 2009 May 11;14(9-10):486-94. Epub 2009 Mar 11.

Department of Pharmacology, Robert Wood Johnson Medical School, University of Medicine & Dentistry of New Jersey, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/j.drudis.2009.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846174PMC
May 2009

Computational discovery of novel low micromolar human pregnane X receptor antagonists.

Mol Pharmacol 2008 Sep 25;74(3):662-72. Epub 2008 Jun 25.

Collaborations in Chemistry, Jenkintown, PA 19046, USA.

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http://dx.doi.org/10.1124/mol.108.049437DOI Listing
September 2008

Ligand specificity and evolution of liver X receptors.

J Steroid Biochem Mol Biol 2008 May 10;110(1-2):83-94. Epub 2008 Mar 10.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15261, United States.

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http://dx.doi.org/10.1016/j.jsbmb.2008.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519238PMC
May 2008

Evolution of the bile salt nuclear receptor FXR in vertebrates.

J Lipid Res 2008 Jul 24;49(7):1577-87. Epub 2008 Mar 24.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1194/jlr.M800138-JLR200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2431107PMC
July 2008

Identification of previously unrecognized antiestrogenic chemicals using a novel virtual screening approach.

Chem Res Toxicol 2006 Dec;19(12):1595-601

Department of Pharmacology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School (UMDNJ-RWJMS), and UMDNJ Informatics Institute, 675 Hoes Lane, Piscataway, New Jersey 08854, USA.

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http://dx.doi.org/10.1021/tx060218kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705242PMC
December 2006

Inhibition of human liver catechol-O-methyltransferase by tea catechins and their metabolites: structure-activity relationship and molecular-modeling studies.

Biochem Pharmacol 2005 May;69(10):1523-31

Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, 164 Frelinghuysen Road, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/j.bcp.2005.01.024DOI Listing
May 2005

Benzotropolone inhibitors of estradiol methylation: kinetics and in silico modeling studies.

Bioorg Med Chem 2005 Apr;13(7):2501-7

Department of Chemical Biology Rutgers, Ernest Mario School of Pharmacy, The State University of New Jersey, 164 Frelinghuysen Rd, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/j.bmc.2005.01.037DOI Listing
April 2005

Computational models for predicting the binding affinities of ligands for the wild-type androgen receptor and a mutated variant associated with human prostate cancer.

Chem Res Toxicol 2003 Dec;16(12):1652-60

Department of Pharmacology, University of Medicine & Dentistry of New Jersey, Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, New Jersey 08854, USA.

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http://dx.doi.org/10.1021/tx034168kDOI Listing
December 2003

Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.

Cancer Res 2003 Nov;63(22):7563-70

Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 164 Frelinghuysen Road, Piscataway, NJ 08854-8020, USA.

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November 2003