Publications by authors named "Ahmet Furkan Kurt"

3 Publications

  • Page 1 of 1

The Effects of Antimicrobial Resistance and the Compatibility of Initial Antibiotic Treatment on Clinical Outcomes in Patients With Diabetic Foot Infection.

Int J Low Extrem Wounds 2021 Apr 15:15347346211004141. Epub 2021 Apr 15.

University of Health Sciences, Ankara Education and Research Hospital, Ankara, Turkey.

We aimed to determine pathogen microorganisms, their antimicrobial resistance patterns, and the effect of initial treatment on clinical outcomes in patients with diabetic foot infection (DFI). Patients with DFI from 5 centers were included in this multicenter observational prospective study between June 2018 and June 2019. Multivariate analysis was performed for the predictors of reinfection/death and major amputation. A total of 284 patients were recorded. Of whom, 193 (68%) were male and the median age was 59.9 ± 11.3 years. One hundred nineteen (41.9%) patients had amputations, as the minor (n = 83, 29.2%) or major (n = 36, 12.7%). The mortality rate was 1.7% with 4 deaths. A total of 247 microorganisms were isolated from 200 patients. The most common microorganisms were (n = 36, 14.6%) and (n = 32, 13.0%). Methicillin resistance rates were 19.4% and 69.6% in and coagulase-negative spp., respectively. Multidrug-resistant was detected in 4 of 22 (18.2%) isolates. Extended-spectrum beta-lactamase-producing Gram-negative bacteria were detected in 20 (38.5%) isolates of (14 of 32) and spp. (6 of 20). When the initial treatment was inappropriate, spp. related reinfection within 1 to 3 months was observed more frequently. Polymicrobial infection ( = .043) and vancomycin treatment ( = .007) were independent predictors of reinfection/death. Multivariate analysis revealed vascular insufficiency ( = .004), hospital readmission ( = .009), C-reactive protein > 130 mg/dL ( = .007), and receiving carbapenems ( = .005) as independent predictors of major amputation. Our results justify the importance of using appropriate narrow-spectrum empirical antimicrobials because higher rates of reinfection and major amputation were found even in the use of broad-spectrum antimicrobials.
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http://dx.doi.org/10.1177/15347346211004141DOI Listing
April 2021

Untreated herpes simplex virus encephalitis without a fatal outcome.

J Neurovirol 2021 Jun 31;27(3):493-497. Epub 2021 Mar 31.

Department of Medical Microbiology, Medical School of Cerrahpasa, Istanbul University, Istanbul, Turkey.

Herpes simplex virus encephalitis (HSE) is the most common sporadic fatal encephalitis. Although timely administered acyclovir treatment decreases mortality, neuropsychiatric sequelae is still common among survivors. Magnetic resonance imaging is frequently utilized for the diagnosis of HSE, which typically involves temporal lobe(s) and can be mixed with brain tumors involving the same area. Here, we report a case of HSE, who received acyclovir with a delay of 90 days because of presumptive tumor diagnosis and survived with minimal sequelae.
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http://dx.doi.org/10.1007/s13365-021-00968-yDOI Listing
June 2021

Candida auris Fungemia and a local spread taken under control with infection control measures: First report from Turkey.

Indian J Med Microbiol 2021 Apr 27;39(2):228-230. Epub 2021 Mar 27.

Istanbul University-Cerrahpasa, Cerrahpasa School of Medicine, Department of Medical Microbiology, Istanbul, Turkey. Electronic address:

Candidaauris, draws attention as a new emerging antifungal resistant pathogen, leading to healthcare-associated infections and outbreaks. This is the first report of C. auris fungemia in a 81-year-old patient, confirmed by sequential analysis, from Turkey. Although the source of the isolate could not be identified, its spread in the hospital has been taken under control by effective infection control measures.
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http://dx.doi.org/10.1016/j.ijmmb.2021.03.007DOI Listing
April 2021
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