Dr. Ahmed M. Agiba, BPharm, MBiotech, MPharm - Ain Shams University - PhD Candidate

Dr. Ahmed M. Agiba

BPharm, MBiotech, MPharm

Ain Shams University

PhD Candidate

Cairo, Cairo | Egypt

Main Specialties: Pharmacology

Additional Specialties: Pharmaceutics, Pharmaceutical Technology, Industrial Pharmacy, Pharmaceutical Biotechnology, Pharmaceutical Nanotechnology

ORCID logohttps://orcid.org/0000-0003-3635-9093

Dr. Ahmed M. Agiba, BPharm, MBiotech, MPharm - Ain Shams University - PhD Candidate

Dr. Ahmed M. Agiba

BPharm, MBiotech, MPharm
Introduction

I've a Bachelor's degree in Pharmaceutical Sciences from College of Pharmaceutical Sciences & Industrial Pharmacy, Misr University for Science & Technology (MUST) in 6th of October City, Egypt with a general grade of Excellent with Honors. I came the Second on my college. Also, a Master in Biotechnology from Faculty of Chemical & System Engineering, University of Chemical Technology & Metallurgy (UCTM) in Sofia, Bulgaria with a general grade of Excellent; a fully-funded scholarship from EU-Commission (Erasmus Mundus Scholarship). Further, a Master's degree in Pharmaceutical Sciences (Pharmaceutics) from Faculty of Pharmacy, Ain Shams University (ASU) in Cairo, Egypt.

Primary Affiliation: Ain Shams University - Cairo, Cairo , Egypt

Specialties:

Additional Specialties:

Research Interests:

Metrics

4

Publications

402

Profile Views

32

Reads

1

PubMed Central Citations

Education
Jan 2018
ICCBS, University of Karachi (Karachi, Pakistan)
Research Fellowship
Dec 2017
Ain Shams University (Cairo, Egypt)
Master in Pharmaceutical Sciences (Pharmaceutics)
Aug 2014
University of Chemical Technology and Metallurgy (Sofia, Bulgaria)
Master in Biotechnology
Sep 2009
Misr University for Science and Technology (6th of October City, Egypt)
Bachelor in Pharmaceutical Sciences
Experience
Oct 2016 - Apr 2018
Pharco-B International
R&D Section Head
Jan 2018
Joint NAM S T Centre - ICCBS Fellowship
Visiting Research Fellow
Feb 2010 - Jul 2015
SIGMA Pharmaceutical Industries
Senior Product Development Specialist
Dec 2014
Bajcsy-Zsilinszky Hospital and Clinic Internship (Budapest, Hungary)
Hospital Pharmacy Intern
Sep 2013
Erasmus Mundus Scholarship
Master Student
Top co-authors
Ahmed S Geneidi
Ahmed S Geneidi

Ain Shams University

2
Maha Nasr
Maha Nasr

Ain Shams University

2
Ahmed B Eldin
Ahmed B Eldin

R&D Department

1

Publications

4Publications

32Reads

1PubMed Central Citations

Geriatric-Oriented High Dose Nutraceutical ODTs: Formulation and Physicomechanical Characterization.

Curr Drug Deliv 2018 Feb;15(2):267-277

Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Monazamet El Wehda El Afrikia St., El Abbassia, 11566, Cairo, Egypt.

View Article
February 2018
18 Reads
2.25 Impact Factor

Enhancing the Intestinal Permeation of the Chondroprotective Nutraceuticals Glucosamine Sulphate and Chondroitin Sulphate Using Conventional and Modified Liposomes.

Curr Drug Deliv 2018 ;15(6):907-916

Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

View Article
January 2018
14 Reads
1 PubMed Central Citation(source)
2.25 Impact Factor

NUTRACEUTICAL FORMULATIONS CONTAINING GLUCOSAMINE AND CHONDROITIN SULPHATE IN THE TREATMENT OF OSTEOARTHRITIS: EMPHASIS ON CLINICAL EFFICACY AND FORMULATION CHALLENGES

Authors:
Ahmed M. Agiba

Int J Curr Pharm Res 2017;9(2):1-7.

International Journal of Current Pharmaceutical Research

Osteoarthritis (OA) is essentially a debilitating disease symptomatized by a gradual loss of articular joint cartilage, causing painful impairment among the population of different ages, particularly patients over the age of 50 y. Nutraceuticals; namely glucosamine and chondroitin have been widely used in the treatment of OA. The chondroprotective properties of the aforementioned agents have been reported, allowing the repair and recovery of the articular surface in OA. The purpose of this review article is to report the current evidence for the use of glucosamine and chondroitin sulphate in the treatment of knee OA with emphasis on their indications for clinical use, effectiveness and safety. It also highlights the role of some advanced formulation technologies in optimizing the delivery of those drugs.

View Article
March 2017
7 Reads

Development & Optimization of Anti-Dandruff Shampoo by Modifying its Rheological Behavior

J. Appl. Cosmetol. 33, 129-138 (July/December 2015)

Journal of Applied Cosmetology

Pharmaceutical product stability is an important issue in pharmaceutical industry. The rheological behavior of a pharmaceutical product affects its stability and performance characteristics such as, foaming properties and filling process during production. Ketoconazole, imidazole antifungal agent, is a weak base with two pKa-values 6.15 and 2.94. It is unstable in aqueous medium and vulnerable to degradation if not properly formulated. Oxidation and hydrolysis are the most degradation routes affecting its stability. The aim of this study to assess the effect of formulation factors such as, pH, the amount of the rheology modifier, rheological behavior and temperature on the stability of ketoconazole in aqueous media. Different formulations of 2 gm% ketoconazole were prepared, using different percent concentrations of the rheology modifier (NaCl) as 0.8 gm%, 0.2 gm%, 0.4 gm%, 0.1 gm% at different pH values 5.5, 6.5 and 7.5. Experimental formulations were prepared at different temperature and time intervals. The measurements of pH and viscosity of the prepared shampoo were evaluated during stability. Stability studies were carried out as per ICH guidelines for 18 months and monitored by validated stability indicating HPLC method (linearity: 60-140 μg/mL; R2=0.9995; acceptable accuracy and precision %RSD < 1.0%). The rheological behavior of the system possess a yield point (minimum shear stress for flow to commence) and time dependency. A reduction in viscosity occurs on shearing with time and rebuilding of viscosity on standing. The key is the rate at which the structure is rebuilt. This is a function of the nature of the thixotropic agent, its concentration in the vehicle or medium, and the amount of agitation before use. The prepared ketoconazole shampoo was high stable at high pH (6.5-7.5) and at temperature < 30 °C during the manufacturing process. Furthermore, the amount of rheology modifier had a high significant effect on the stability of ketoconazole. Formulations containing 0.1 gm% NaCl showed better stability and exhibited ideal thixotropic rheological behavior. The rheology of dispersed systems is among the most important of their physical properties, which influences not only the physical stability of the systems, but often also profoundly affects the performance features, their quality, and their utility. In dealing with rheological parameters, and in case of thixotropic systems, long shearing times should be avoided. Temperature changes can also produce spurious results, since shear stress at a constant shear rate, is also a function of temperature. It is important to consider the optimum pH for the product, since the properties of the product, particularly rheology, can be quite dependent on the pH of the system. In conclusion, the expected shelf life of the final ketoconazole formulation was stable for 18 months.

View Article
December 2015
5 Reads
Top co-authors
Ahmed S Geneidi
Ahmed S Geneidi

Ain Shams University

2
Maha Nasr
Maha Nasr

Ain Shams University

2
Ahmed B Eldin
Ahmed B Eldin

R&D Department

1