Publications by authors named "Ahmed Idbaih"

100Publications

Profiling Anti-Apoptotic BCL-xL Protein Expression in Glioblastoma Tumorspheres.

Cancers (Basel) 2020 Oct 2;12(10). Epub 2020 Oct 2.

Cancer Research Centre of Lyon (CRCL) INSERM 1052, CNRS 5286, 69008 Lyon, France.

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http://dx.doi.org/10.3390/cancers12102853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599739PMC
October 2020

Central nervous system involvement in Erdheim-Chester disease: An observational cohort study.

Neurology 2020 11 4;95(20):e2746-e2754. Epub 2020 Sep 4.

From Service de Médecine Interne 2, Centre National de Référence Maladies Systémiques Rares et Histiocytoses (F.C.A., Z.A., J.H.), Service de Neuroradiologie (D.G., B.L.-Y.), Service d'Anatomopathologie (F.C.), Service de Médecine Nucléaire (P.M.), Service de Neuropathologie (D.S.), Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne Université; Service de Neurologie 2-Mazarin (A.I., K.H.-Z.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Sorbonne Université, Paris; Département de Pathologie (J.-F.E.), EA4340, Université Versailles-Saint Quentin, Assistance Publique Hôpitaux de Paris, Hôpital Ambroise Paré, Boulogne; and Service d'Hématologie Pédiatrique, Centre de Référence National Histiocytoses (J.D.), Hôpital Trousseau, Sorbonne Université, Paris, France.

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http://dx.doi.org/10.1212/WNL.0000000000010748DOI Listing
November 2020

Phenotypic selection through cell death: stochastic modelling of O-6-methylguanine-DNA methyltransferase dynamics.

R Soc Open Sci 2020 Jul 8;7(7):191243. Epub 2020 Jul 8.

Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, York House, Dublin, Ireland.

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http://dx.doi.org/10.1098/rsos.191243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428254PMC
July 2020

One-year survival of patients with high-grade glioma discharged alive from the intensive care unit.

J Neurol 2020 Aug 29. Epub 2020 Aug 29.

Médecine Intensive Et Réanimation (Département R3S), Service de Pneumologie, AP-HP, Site Pitié-Salpêtrière, Groupe Hospitalier Universitaire APHP-Sorbonne Université, Service de Neurologie 2-Mazarin, 75013, Paris, France.

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http://dx.doi.org/10.1007/s00415-020-10191-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456207PMC
August 2020

Rare Primary Central Nervous System Tumors in Adults: An Overview.

Front Oncol 2020 26;10:996. Epub 2020 Jun 26.

Sorbonne Université, Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Service de Neurologie 2-Mazarin, Paris, France.

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http://dx.doi.org/10.3389/fonc.2020.00996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333775PMC
June 2020

Initial surgical resection and long time to occurrence from initial diagnosis are independent prognostic factors in resected recurrent IDH wild-type glioblastoma.

Clin Neurol Neurosurg 2020 Sep 8;196:106006. Epub 2020 Jun 8.

Sorbonne Université, Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Service de Neurologie 2-Mazarin, F-75013, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.clineuro.2020.106006DOI Listing
September 2020

Mechanisms and therapeutic implications of hypermutation in gliomas.

Nature 2020 04 15;580(7804):517-523. Epub 2020 Apr 15.

Department of Oncologic Pathology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41586-020-2209-9DOI Listing
April 2020

5-Azacitidine in patients with IDH1/2-mutant recurrent glioma.

Neuro Oncol 2020 08;22(8):1226-1228

Sorbonne University, Institute of the Brain and Spinal Cord, Department of Neurosurgery, University Hospitals of Pitié Salpêtrière‒Charles Foix, Neurology Service 2-Mazarin, Paris, France.

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http://dx.doi.org/10.1093/neuonc/noaa074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594550PMC
August 2020

Dissecting the role of crosstalk between glioblastoma subpopulations in tumor cell spreading.

Oncogenesis 2020 Feb 5;9(2):11. Epub 2020 Feb 5.

Department for Bio-Medical Research, Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, 91120, Israel.

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http://dx.doi.org/10.1038/s41389-020-0199-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002777PMC
February 2020

Diabetes Mellitus, Extreme Insulin Resistance, and Hypothalamic-Pituitary Langerhans Cells Histiocytosis.

Case Rep Endocrinol 2019 23;2019:2719364. Epub 2019 Jun 23.

Diabetology-Metabolism Dpt, Sorbonne Université, APHP, Institut Hospitalo-Universitaire de Cardiometabolisme et Nutrition (ICAN), Pitié-Salpêtrière-Charles Foix Hospital, 75013 Paris, France.

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http://dx.doi.org/10.1155/2019/2719364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612391PMC
June 2019

Endocrine manifestations in a cohort of 63 adulthood and childhood onset patients with Langerhans cell histiocytosis.

Eur J Endocrinol 2019 Sep;181(3):275-285

Service d'Endocrinologie et Médecine de la Reproduction, Hôpital Universitaire Pitié Salpêtrière - Charles Foix, Sorbonne Université, Faculté de Médecine, Paris, France.

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http://dx.doi.org/10.1530/EJE-19-0177DOI Listing
September 2019

Temporary blood-brain barrier disruption by low intensity pulsed ultrasound increases carboplatin delivery and efficacy in preclinical models of glioblastoma.

J Neurooncol 2019 Aug 13;144(1):33-41. Epub 2019 Jun 13.

Sorbonne Université, Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Service de Neurologie 2-Mazarin, 75013, Paris, France.

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http://dx.doi.org/10.1007/s11060-019-03204-0DOI Listing
August 2019

Imaging necrosis during treatment is associated with worse survival in EORTC 26101 study.

Neurology 2019 06 10;92(24):e2754-e2763. Epub 2019 May 10.

From the University Medical Center & German Cancer Research Center (M.N., F.S., I.H., P.K., M.P., M.B., W.W.), Heidelberg, Germany; EORTC Headquarters (T.G., V.G.), Brussels, Belgium; Brain Tumor Center at Erasmus MC Cancer Institute (J.E.C.B., W.T., M.J.v.d.B.), Rotterdam, the Netherlands; Medical Oncology Department (A.A.B.), AUSL-Bologna-IRCCS Scienze Neurologiche, Bologna, Italy; Haaglanden Medical Center (M.J.B.T.), the Hague; Leiden University Medical Center (M.J.B.T.), the Netherlands; Institut Gustave Roussy (J.D.), Villejuif; Sorbonne Université (A.I.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Service de Neurologie 2-Mazarin, Paris; Institut de Cancerologie de l'Ouest (ICO)-Centre Rene Gauducheau (M.C.), Saint-Herblain, France; Leuven Cancer Institute-KU Leuven (P.M.C.), Belgium; Department of Neurology and Brain Tumor Center (M.W.), University Hospital and University of Zurich, Switzerland; Institut Régional du Cancer Montpellier (M.F.); University of Lille (E.L.R.), U-1192, Inserm; CHU Lille (E.L.R.), General and Stereotaxic Neurosurgery Service; Oscar Lambret Center (E.L.R.), Neurology, Lille, France; Department of Neurology (M.P.), Medical Faculty Mannheim, Heidelberg University, Germany; and Department of Neurology (M.N.), Medical University Innsbruck, Austria.

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http://dx.doi.org/10.1212/WNL.0000000000007643DOI Listing
June 2019

Etiology and prognosis of acute respiratory failure in patients with primary malignant brain tumors admitted to the intensive care unit.

J Neurooncol 2019 Mar 7;142(1):139-148. Epub 2018 Dec 7.

Sorbonne Universités, UPMC Univ Paris 06, INSERM, UMRS_1158 Neurophysiologie respiratoire expérimentale et clinique, Paris, France.

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http://dx.doi.org/10.1007/s11060-018-03074-yDOI Listing
March 2019

Neuro-oncology: A rapidly evolving multidisciplinary speciality.

Presse Med 2018 Nov - Dec;47(11-12 Pt 2):e185-e186

Sorbonne université, Inserm, CNRS, UMR S 1127, institut du cerveau et de la moelle épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié-Salpêtrière-Charles-Foix, service de neurologie 2-Mazarin, 75013 Paris, France.

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http://dx.doi.org/10.1016/j.lpm.2018.11.016DOI Listing
December 2018

CNS inflammatory disorder after concurrent radiotherapy-temozolomide and nivolumab in a glioblastoma patient.

Neuro Oncol 2019 01;21(1):139-141

Sorbonne Université, Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière?Charles Foix, Paris, France.

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http://dx.doi.org/10.1093/neuonc/noy168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303433PMC
January 2019

Vemurafenib and cobimetinib overcome resistance to vemurafenib in -mutant ganglioglioma.

Neurology 2018 09 17;91(11):523-525. Epub 2018 Aug 17.

From Sorbonne Université (M.T., A.I., M.S., A.L.D.S.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Service de Neurologie 2-Mazarin, Paris, France; Department of Oncologic Pathology (M.T., K.L.L.), Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA; Department of Neuroradiology (J.G., S.C.A.), Pharmacy Department (K.S.), and Departments of Neurosurgery (S.A.), Pathology (C.V.), and Neurology (A.L.D.S.), Hôpital Foch, Suresnes; Department of Radiology (J.S.), Fondation Ophtalmologique Adolphe de Rothschild, Paris; Département de Génétique (G.P., A.-P.G.-R., P.L.-P.), and Service de Biochimie, UF de Pharmacogénétique et Oncologie Moléculaire (H.B.), Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges-Pompidou, Paris; INSERM (G.P., H.B., P.L.-P.), UMR S 1147, Paris; Drug Development Department (A.H.), Gustave Roussy, Université Paris-Saclay, Villejuif; INSERM (A.-P.G.-R.), UMR970, Paris-Cardiovascular Research Center, Equipe Labellisée par la Ligue contre le Cancer, Paris; and Université Paris Descartes (H.B., A.-P.G.-R., P.L.-P.), Sorbonne Paris Cité, Faculté de Médecine, Paris, France.

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http://dx.doi.org/10.1212/WNL.0000000000006171DOI Listing
September 2018

Bevacizumab and temozolomide in patients with first recurrence of WHO grade II and III glioma, without 1p/19q co-deletion (TAVAREC): a randomised controlled phase 2 EORTC trial.

Lancet Oncol 2018 09 13;19(9):1170-1179. Epub 2018 Aug 13.

The Brain and Spine Institute (ICM), Sorbonne Université, The National Institute of Health and Medical Research (INSERM), National Centre for Scientific Research (CNRS), Public Assistance-Paris Hospitals (AP-HP), Hôpital Pitié-Salpêtrière, Paris, France.

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183036
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http://dx.doi.org/10.1016/S1470-2045(18)30362-0DOI Listing
September 2018

Interactions between tumor-associated macrophages and tumor cells in glioblastoma: unraveling promising targeted therapies.

Expert Rev Neurother 2018 09 22;18(9):729-737. Epub 2018 Aug 22.

a Sorbonne Université, Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM, AP-HP , Hôpitaux Universitaires Pitié Salpêtrière - Charles Foix , Service de Neurologie 2-Mazarin, Paris , France.

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http://dx.doi.org/10.1080/14737175.2018.1510321DOI Listing
September 2018

Machine Learning for Better Prognostic Stratification and Driver Gene Identification Using Somatic Copy Number Variations in Anaplastic Oligodendroglioma.

Oncologist 2018 12 17;23(12):1500-1510. Epub 2018 Jul 17.

Sorbonne Université, INSERM U1127, CNRS UMR7225, Institut du Cerveau et de la Moelle épinière (ICM), AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Service de Neurologie 2-Mazarin, Paris, France

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http://dx.doi.org/10.1634/theoncologist.2017-0495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292528PMC
December 2018

Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development.

Cancer Cell 2018 07;34(1):163-177.e7

Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424337PMC
July 2018

actionable mutations, molecular specificities, and outcome of adult midline gliomas.

Neurology 2018 06 4;90(23):e2086-e2094. Epub 2018 May 4.

From Sorbonne Université (A.P., G.B., F.B., M.T., E.T., S.M., Y.S., A.I., K.H.-X., J.-Y.D., K.M., A.L.D.S., M.S.), UPMC Univ Paris 06 UMR S 1127, Inserm U 1127, CNRS UMR 7225, ICM; Service de Neurologie 2 (A.P., G.B., M.T., A.I., K.H.-X., J.-Y.D., M.S.) and Laboratoire R Escourolle 2 (F.B., K.M.), AP-HP, Hôpital de la Pitié-Salpêtrière, Paris, France; Neuroscience Consortium (A.P., G.B.), Monza Policlinico and Pavia Mondino, University of Pavia, Italy; Centre d'Imagerie (J.S.), Fondation A de Rothschild; Laboratoire d'Anatomie Pathologique (M.P.), AP-HP, Hôpital Lariboisière, Paris, France; Pathology Unit (E.T.), AOU "Maggiore della Carità" di Novara, Italy; Onconeurotek Tumour Bank (J.-Y.D., K.M., M.S.), GH Pitié-Salpêtrière; and Department of Neurology (A.L.D.S.), Foch Hospital, Suresnes, Paris, France.

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http://dx.doi.org/10.1212/WNL.0000000000005658DOI Listing
June 2018

ATP binding cassette (ABC) transporters: expression and clinical value in glioblastoma.

J Neurooncol 2018 Jul 8;138(3):479-486. Epub 2018 Mar 8.

Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 04 UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM, 75013, Paris, France.

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http://dx.doi.org/10.1007/s11060-018-2819-3DOI Listing
July 2018

Liquid Biopsy in Primary Brain Tumors: Looking for Stardust!

Curr Neurol Neurosci Rep 2018 03 9;18(3):13. Epub 2018 Mar 9.

Sorbonne Université, Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Service de Neurologie 2-Mazarin, F-75013, Paris, France.

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http://link.springer.com/10.1007/s11910-018-0820-z
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http://dx.doi.org/10.1007/s11910-018-0820-zDOI Listing
March 2018

Phenotypes and survival in Erdheim-Chester disease: Results from a 165-patient cohort.

Am J Hematol 2018 May 10;93(5):E114-E117. Epub 2018 Feb 10.

Internal Medicine Department 2, Pitié-Salpêtrière Hospital, French National Centre for Rare Systemic Diseases, AP-HP, Paris, 75013, France.

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http://doi.wiley.com/10.1002/ajh.25055
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http://dx.doi.org/10.1002/ajh.25055DOI Listing
May 2018

Lomustine and Bevacizumab in Progressive Glioblastoma.

N Engl J Med 2017 11;377(20):1954-1963

From the University Medical Center and German Cancer Research Center, Heidelberg, Germany (W.W., M.B., F.S., I.H., A.D., M.P.); the European Organization for Research and Treatment of Cancer, Brussels (T.G., V.G.), and Leuven Cancer Institute-KU Leuven, Leuven (P.M.C.) - both in Belgium; Haaglanden Medical Center, The Hague (M.T.), Erasmus MC Cancer Institute, Rotterdam (W.T., J.C.B., M.J.B.), and VU University Medical Center, Amsterdam (M.K.) - all in the Netherlands; the Medical Oncology Department, Azienda Unità Sanitaria Locale di Bologna-IRCCS Istituto delle Scienze Neurologiche, Bologna, Italy (A.A.B.); Institut Gustave Roussy, Villejuif (J.D.), Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Service de Neurologie 2-Mazarin, INSERM Unité 1127, Centre National de la Recherche Scientifique Unité Mixte de Recherche (UMR) 7225, Sorbonne Universités, University Pierre and Marie Curie 06 UMR S1127, and Institut du Cerveau et de la Moelle Épinière, Paris (A.I.), Institut de Cancerologie de l'Ouest-Centre Rene Gauducheau, Saint-Herblain (M.C.), Institut Régional du Cancer Montpellier, Montpellier (M.F.), and Centre Hospitalier Régional Universitaire de Lille, Lille (E.L.R., F.D.) - all in France; and the Departments of Oncology and Neurology, University Hospital and University of Zurich, Zurich, Switzerland (R.S., M.W.).

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http://dx.doi.org/10.1056/NEJMoa1707358DOI Listing
November 2017

Prognosis of patients with primary malignant brain tumors admitted to the intensive care unit: a two-decade experience.

J Neurol 2017 Nov 9;264(11):2303-2312. Epub 2017 Oct 9.

Neurophysiologie Respiratoire Expérimentale et Clinique, Sorbonne Universités, UPMC Univ Paris 06, INSERM, UMRS_1158, Paris, France.

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http://dx.doi.org/10.1007/s00415-017-8624-7DOI Listing
November 2017

Targeted therapies in 54 patients with Erdheim-Chester disease, including follow-up after interruption (the LOVE study).

Blood 2017 09 30;130(11):1377-1380. Epub 2017 Jun 30.

Department of Internal Medicine 2, Assistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière Hospital, French National Centre for Rare Systemic Diseases, Paris, France.

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http://www.bloodjournal.org/lookup/doi/10.1182/blood-2017-03
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http://dx.doi.org/10.1182/blood-2017-03-771873DOI Listing
September 2017

Same-day genomic and epigenomic diagnosis of brain tumors using real-time nanopore sequencing.

Acta Neuropathol 2017 11 21;134(5):691-703. Epub 2017 Jun 21.

Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle épinière (ICM), Paris, France.

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http://dx.doi.org/10.1007/s00401-017-1743-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645447PMC
November 2017

Histiocytoses: emerging neoplasia behind inflammation.

Lancet Oncol 2017 02;18(2):e113-e125

Service de Médecine Interne 2, Centre National de Référence Maladies Auto Immunes Systémiques Rares, Institut E3M, Hôpital Pitié-Salpêtrière, Paris, France.

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http://dx.doi.org/10.1016/S1470-2045(17)30031-1DOI Listing
February 2017

Analysis of temozolomide resistance in low-grade gliomas using a mechanistic mathematical model.

Fundam Clin Pharmacol 2017 Jun 24;31(3):347-358. Epub 2017 Jan 24.

Laboratoire Jean Kuntzmann, UMR CNRS 5224, Université Grenoble-Alpes, 38401, Saint-Martin-d'Heres, France.

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http://dx.doi.org/10.1111/fcp.12259DOI Listing
June 2017

[Neuro-Langerhans cell histiocytosis].

Presse Med 2017 Jan 2;46(1):79-84. Epub 2016 Nov 2.

AP-HP, groupe hospitalier Pitié-Salpêtrière, service de neurologie 2-Mazarin, Paris, France; Université Pierre-et-Marie-Curie - Paris 6, centre de recherche de l'institut du cerveau et de la moelle épinière (CRICM), UMRS 975, Paris, France; Inserm U 975, Paris, France; CNRS, UMR 7225, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.lpm.2016.09.014DOI Listing
January 2017

Tumor cells with neuronal intermediate progenitor features define a subgroup of 1p/19q co-deleted anaplastic gliomas.

Brain Pathol 2017 Sep 28;27(5):567-579. Epub 2016 Oct 28.

POLA Network investigators: Amiens: Christine Desenclos, Henri Sevestre; Angers: Philippe Menei, Audrey Rousseau; Besançon: Joel Godard, Gabriel Viennet; Bobigny: Antoine Carpentier; Bordeaux: Sandrine Eimer, Hugues Loiseau; Brest: Phong Dam-Hieu, Isabelle Quintin-Roué; Caen: Jean-Sebastien Guillamo, Emmanuelle Lechapt-Zalcman; Clermont-Ferrand:Jean-Louis Kemeny, Toufik Khallil; Clichy: Dominique Cazals-Hatem, Thierry Faillot; Cornebarrieu: Ioana Carpiuc, Pomone Richard; Créteil: Caroline Le Guerinel; Colmar: Claude Gaultier, Marie-Christine Tortel; Dijon: Marie-Hélène Aubriot-Lorton, François Ghiringhelli; Kremlin-Bicêtre: Clovis Adam, Fabrice Parker; Lille: Claude-Alain Maurage, Carole Ramirez; Limoges: Edouard Marcel Gueye, François Labrousse; Lyon: Anne Jouvet; Marseille: Olivier Chinot; Montpellier: Luc Bauchet, Valérie Rigau; Nancy: Patrick Beauchesne, Dr Guillaume Gauchotte; Nantes: Mario Campone, Delphine Loussouarn; Nice: Denys Fontaine, Fanny Vandenbos; Orléans: Claire Blechet, Mélanie Fesneau; Paris: Jean Yves Delattre (national coordinator of the network), Selma Elouadhani-Hamdi, Damien Ricard; Poitiers: Delphine Larrieu-Ciron, Pierre-Marie Levillain; Reims: Philippe Colin, Marie-Danièle Diebold; Rennes: Danchristian Chiforeanu, Elodie Vauléon; Rouen: Olivier Langlois, Annie Laquerrière; Saint-Etienne: Marie Janette Motsuo Fotso, Michel Peoc'h; Saint-Pierre de la réunion: Marie Andraud, Gwenaelle Runavot; Strasbourg: Marie-Pierre Chenard, Georges Noel; Suresnes: Dr Stéphane Gaillard, Dr Chiara Villa; Toulon: Nicolas Desse; Toulouse: Elisabeth Cohen-Moyal, Emmanuelle Uro-Coste; Villejuif: Frédéric Dhermain.

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http://dx.doi.org/10.1111/bpa.12434DOI Listing
September 2017

Neurolymphomatosis as a relapse of primary cerebral nervous system lymphoma.

Leuk Lymphoma 2017 03 9;58(3):729-731. Epub 2016 Aug 9.

a Service de Neurologie 2-Mazarin , AP-HP, Groupe Hospitalier Pitié-Salpêtrière , Paris , France.

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http://dx.doi.org/10.1080/10428194.2016.1211277DOI Listing
March 2017

Radiation plus Chemotherapy in Low-Grade Glioma.

N Engl J Med 2016 08;375(5):489-90

Hôpital Universitaire Pitié-Salpêtrière, Paris, France

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http://dx.doi.org/10.1056/NEJMc1605897DOI Listing
August 2016

Chromosome 17p Homodisomy Is Associated With Better Outcome in 1p19q Non-Codeleted and IDH-Mutated Gliomas.

Oncologist 2016 09 8;21(9):1131-5. Epub 2016 Jul 8.

Sorbonne Universités, Université Pierre et Marie Curie, Université Paris 06, Centre de Recherche de l'Institut du Cerveau et de la Moelle Épinière, Paris, France INSERM U1127, Paris, France Centre National de la Recherche Scientifique, Unité de Recherche Mixte 7225, Paris, France OncoNeuroTek, Paris, France Service de Neurologie 2, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique Hôpitaux de Paris, Paris, France

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http://theoncologist.alphamedpress.org/cgi/doi/10.1634/theon
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http://dx.doi.org/10.1634/theoncologist.2016-0003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016064PMC
September 2016

Blood-brain barrier, cytotoxic chemotherapies and glioblastoma.

Expert Rev Neurother 2016 11 4;16(11):1285-1300. Epub 2016 Jul 4.

a Inserm U 1127, CNRS UMR 7225 , Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM , Paris , France.

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http://dx.doi.org/10.1080/14737175.2016.1202761DOI Listing
November 2016

Clinical trial of blood-brain barrier disruption by pulsed ultrasound.

Sci Transl Med 2016 06;8(343):343re2

Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, F-75013 Paris, France. INSERM, U 1127, F-75013 Paris, France. CNRS, UMR 7225, F-75013, Paris, France. ICM, F-75013 Paris, France. AP-HP, Hôpitaux Universitaires La Pitié-Salpêtrière-Charles Foix, Service de Neurologie 2-Mazarin, F-75013 Paris, France.

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http://stm.sciencemag.org/content/scitransmed/8/343/343re2.f
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http://dx.doi.org/10.1126/scitranslmed.aaf6086DOI Listing
June 2016

Prevalence of IDH1/2 Mutations in Different Subtypes of Glioma in the North-East Population of Morocco.

Asian Pac J Cancer Prev 2016 ;17(5):2649-53

Groupe Hospitalier Pitie-Salpetriere, Laboratoire de Neuropathologie R Escourolle, Paris, France E-mail :

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February 2017

Basal Ganglia Germinoma in an Adult.

World Neurosurg 2016 Aug 27;92:584.e11-584.e14. Epub 2016 May 27.

AP-HP, Hôpitaux Universitaires La Pitié Salpêtriére-Charles Foix, Service de Neuropathologie-Escourolle, Paris, France.

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http://dx.doi.org/10.1016/j.wneu.2016.05.041DOI Listing
August 2016

Mitotic index, microvascular proliferation, and necrosis define 3 pathological subgroups of prognostic relevance among 1p/19q co-deleted anaplastic oligodendrogliomas.

Neuro Oncol 2016 06;18(6):888-90

APHM, Hôpital de la Timone, Service d'Anatomie Pathologique et de Neuropathologie, Marseille, France (D.F.B.); Aix-Marseille Université, Inserm, CRO2 UMR_S 911, Marseille, France (D.F.B., C.C.); AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Service de Neuropathologie Raymond Escourolle, Paris, France (K.M.); Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMCUniv Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM, F-75013, Paris, France (K.M., C.D., C.C., A.I., J.-Y.D.); AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Service de Neurologie 2-Mazarin, F75013, Paris, France (K.M., C.D., C.C., A.I., J.-Y.D.); Centre de Pathologie et de Neuropathologie Est, Bron, France (A.J.); CHU Toulouse, Hôpital Rangueil, Service d'Anatomie Pathologique et Histologie-Cytologie, Toulouse, France (E.U.-C.); Inserm U1037, Centre de Recherche en Cancérologie de Toulouse, Université de Toulouse, France (E.U.-C.); CHU Saint-Etienne, Hôpital Nord, Service d'Anatomie et Cytologie Pathologiques, Saint-Etienne, France (F.F., M.P.); CHU Lille, Pôle Pathologie Biologique, Service Anatomie Pathologique, Lille, France (C.-A.M.); CHU Nancy, Hôpital Central, Laboratoire d'Anatomie Pathologique, Nancy, France (J.-M.V.); APHP, Hôpital Lariboisière, Service d'Anatomie et Cytologie Pathologique, Paris, France (M.P.); CHU Caen, Hôpital de la Côte de Nacre, Service d'anatomie Pathologique, Caen, France (E.L.-Z.); CNRS, UMR 6301 ISTCT, CERVOxy, GIP CYCERON, Caen, France (E.L.-Z.); CHU Bordeaux, Hôpital Pellegrin, Service de Pathologie - Neuropathologie, Bordeaux, France (S.E.); EA2406, Histologie et pathologie moléculaire des tumeurs, Université Bordeaux Segalen, Bordeaux, France (S.E.); CHU Besançon, Hôpital Jean Minjoz, Service Anatomie et Cytologie Pathologiques, Besançon, France (G.V.); CHU Brest, Hôpital de la Cavale Blanche, Service Anatomie Pathologique, Brest, France (I.Q.-R.); CHU Dijon, Plateau technique de biologie G. Mack

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http://dx.doi.org/10.1093/neuonc/now085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864268PMC
June 2016

[Targeted therapy in glioblastoma: update and perspectives].

Bull Acad Natl Med 2015 11;199(8-9):1323-1329

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November 2015

Preclinical Efficacy of the MDM2 Inhibitor RG7112 in MDM2-Amplified and TP53 Wild-type Glioblastomas.

Clin Cancer Res 2016 Mar 19;22(5):1185-96. Epub 2015 Oct 19.

Inserm, U 1127, Paris, France. CNRS, UMR 7225, Paris, France. Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Paris, France. Institut du Cerveau et de la Moëlle épinière, ICM, 47, Bd de l'Hôpital, Paris, France. AP-HP, Hôpital universitaire Pitié-Salpêtrière, Service de Neurologie 2-Mazarin, 47, Bd de l'Hôpital, Paris, France. AP-HP, Hôpital de la Pitié-Salpêtrière, Service de Neuropathologie R Escourolle, 47, Bd de l'Hôpital, Paris, France.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-1015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842012PMC
March 2016

Emerging circulating biomarkers in glioblastoma: promises and challenges.

Expert Rev Mol Diagn 2015 ;15(10):1311-23

c 3 AP-HP, Hôpital Universitaire la Pitié Salpêtrière, Service de Neurologie 2-Mazarin, F-75013, Paris, France.

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http://dx.doi.org/10.1586/14737159.2015.1087315DOI Listing
June 2016

Molecular classification of anaplastic oligodendroglioma using next-generation sequencing: a report of the prospective randomized EORTC Brain Tumor Group 26951 phase III trial.

Neuro Oncol 2016 Mar 9;18(3):388-400. Epub 2015 Sep 9.

Department of Pathology, Rotterdam, the Netherlands (H.J.D., P.N.A., J.M.K., W.N.M.D.); Department of Neurology, Erasmus Medical Center, Rotterdam, the Netherlands (P.J.F.); Groupe Hospitalier Pitie Salpetriere, Service de Neurologie Mazarin, Paris, France (M.S., A.I.); Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands (P.W.); Department of Pathology, Free University Medical Center, Amsterdam, the Netherlands (P.W.); Department of Neurology, University Medical Center Groningen, Groningen, the Netherlands (R.E.); Department of Pathology, UMCU, Utrecht, the Netherlands (W.S.); Department of Neurology, St. Elisabeth Hospital, Tilburg, the Netherlands (C.T.); European Organisation for Research and Treatment of Cancer Data Center, Brussels, Belgium (T.G.); Department of Neurology/Neuro-oncology, Erasmus MC Cancer Center, Rotterdam, the Netherlands (M.J.v.d.B.).

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http://dx.doi.org/10.1093/neuonc/nov182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767239PMC
March 2016

Clinical Spectrum of Encephalitis Associated With Antibodies Against the α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptor: Case Series and Review of the Literature.

JAMA Neurol 2015 Oct;72(10):1163-9

Université Claude Bernard Lyon 1, Lyon, France2Institut National de la Santé et de la Recherche Médicale (INSERM) et Centre National de la Recherche Scientifique (CNRS), Equipe Neuro-oncologie et Neuro-inflammation, Centre de Recherche en Neurosciences de.

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http://archneur.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaneurol.2015.1715DOI Listing
October 2015

Differential gene methylation in paired glioblastomas suggests a role of immune response pathways in tumor progression.

J Neurooncol 2015 Sep 30;124(3):385-92. Epub 2015 Jul 30.

Service de Neurologie 2-Mazarin, Groupe Hospitalier Pitié-Salpêtrière, Hôpital Universitaire la Pitié Salpêtrière, APHP, 47-83 Boulevard de l'Hôpital, 75013, Paris, France.

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http://dx.doi.org/10.1007/s11060-015-1869-zDOI Listing
September 2015

Molecular profiling of gliomas: potential therapeutic implications.

Expert Rev Anticancer Ther 2015 28;15(8):955-62. Epub 2015 Jun 28.

AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Service de neurologie 2-Mazarin, Paris, France.

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http://dx.doi.org/10.1586/14737140.2015.1062368DOI Listing
April 2016

Preclinical impact of bevacizumab on brain and tumor distribution of irinotecan and temozolomide.

J Neurooncol 2015 Apr 13;122(2):273-81. Epub 2015 Jan 13.

Clinical Pharmacy Department - EA 4123, College of Pharmacy, Paris Sud University, 5 rue Jean Baptiste Clement, 92296, Châtenay Malabry, France,

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http://dx.doi.org/10.1007/s11060-015-1717-1DOI Listing
April 2015

Dural Arteriovenous Fistula Mimicking a Brainstem Glioma.

J Neuroimaging 2015 Nov-Dec;25(6):1053-5. Epub 2015 Feb 20.

AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Service de neurologie 2-Mazarin, Paris, France.

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http://dx.doi.org/10.1111/jon.12220DOI Listing
December 2016

Reproducible and sustained efficacy of targeted therapy with vemurafenib in patients with BRAF(V600E)-mutated Erdheim-Chester disease.

J Clin Oncol 2015 Feb 24;33(5):411-8. Epub 2014 Nov 24.

Julien Haroche, Fleur Cohen-Aubart, Philippe Maksud, Aurélie Drier, Dan Tolédano, Stéphane Barete, Frédéric Charlotte, Philippe Cluzel, Neïla Benameur, Philippe A. Grenier, Ahmed Idbaih, Baptiste Hervier, Laurent Arnaud, and Zahir Amoura, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Pitié-Salpêtrière; Philippe Maksud, Stéphane Barete, Frédéric Charlotte, Philippe Cluzel, Philippe A. Grenier, Ahmed Idbaih, Julien Haroche, Fleur Cohen-Aubart, Baptiste Hervier, Laurent Arnaud, and Zahir Amoura, Paris VI University Pierre et Marie Curie; Jean Donadieu, AP-HP, Hôpital Trousseau, French National Center for Histiocytosis, Paris; Jean-François Emile, EA4340-BCOH, Versailles University, and AP-HP, Hôpital Ambroise Paré, Boulogne; Sophie Besnard, Centre Hospitalier Universitaire de Rennes, Pontchaillou University Hospital, Rennes Cedex; Jean-Paul Ory, Centre Hospitalier Régional de Vesoul, Vesoul; François Lifermann, Hôpital de Dax-Côte d'Argent, Dax; Brigitte Granel, Assistance Publique-Hôpitaux de Marseille, Hôpital Nord, Marseille; and Bruno Graffin, Hôpital d'Instruction des Armées Legouest, Metz, France.

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http://dx.doi.org/10.1200/JCO.2014.57.1950DOI Listing
February 2015

DGKI methylation status modulates the prognostic value of MGMT in glioblastoma patients treated with combined radio-chemotherapy with temozolomide.

PLoS One 2014 18;9(9):e104455. Epub 2014 Sep 18.

CNRS, UMR 6290, Institut Génétique et Développement de Rennes, Rennes, France; Université Rennes 1, Université Européenne de Bretagne, Biosit, Faculté de Médecine, Rennes, France; Plate-forme Génomique Santé Biogenouest, Biosit, Rennes, France; Centre Hospitalier Universitaire de Rennes, Service de Génétique Moléculaire et Génomique, Rennes, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104455PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169423PMC
June 2015

Dramatic response of a BRAF V600E-mutated primary CNS histiocytic sarcoma to vemurafenib.

Neurology 2014 Oct 10;83(16):1478-80. Epub 2014 Sep 10.

From the Université Pierre et Marie Curie-Paris 6 (A.I., K.M., C.C., J.-Y.D., K.H.-X.), Centre de Recherche de l'Institut du Cerveau et de la Moelle Epinière (CRICM), UMRS 975; Inserm U 975 (A.I., K.M., C.C., J.-Y.D., K.H.-X.); CNRS (A.I., K.M., C.C., J.-Y.D., K.H.-X.), UMR 7225; AP-HP (A.I., K.M., D.G., H.B., N.B., V.-C.B., D.P., N.M.-D., J.H., L.F., N.Z., J.-Y.D., K.H.-X.), Groupe Hospitalier Pitié-Salpêtrière, Paris; Versailles University & Ambroise Paré Hospital (J.-F.E.), AP-HP, Boulogne; AltraBio (S.d.B.), Lyon; and AP-HP (J.D.), Hôpital Trousseau, Paris, France.

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http://dx.doi.org/10.1212/WNL.0000000000000880DOI Listing
October 2014

Marked efficacy of vemurafenib in suprasellar Erdheim-Chester disease.

Neurology 2014 Sep 29;83(14):1294-6. Epub 2014 Aug 29.

From AP-HP (F.C.-A., P.M., D.G., A.I., D.C., N.B., Z.A., J.H.), Groupe Hospitalier Pitié-Salpêtrière, Paris; Université Paris VI Pierre et Marie Curie (F.C.-A., P.M., Z.A., D.G., A.I., D.C., J.H.); AP-HP (J.-F.E.), Hôpital Ambroise-Paré, Boulogne; Université de Versailles (J.-F.E.); and AP-HP (Y.A.), Hôpital Cochin, Paris, France.

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http://dx.doi.org/10.1212/WNL.0000000000000832DOI Listing
September 2014

Diagnostic and prognostic value of preoperative combined GFAP, IGFBP-2, and YKL-40 plasma levels in patients with glioblastoma.

Cancer 2014 Dec 19;120(24):3972-80. Epub 2014 Aug 19.

Neurology Service 2, Mazarin Division, Pitié-Salpêtrière Hospital, AP-HP; Sorbonne Universités, UPMC Univ Paris 06, UM 75; CNRS, UMR 7225; Inserm, U1127; ICM, F-75013, Paris, France; Department of Neurology, Clinic of the University of Navarra, University of Navarra School of Medicine, Pamplona, Spain.

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http://dx.doi.org/10.1002/cncr.28949DOI Listing
December 2014

Predictive biomarkers investigated in glioblastoma.

Expert Rev Mol Diagn 2014 Sep 5;14(7):883-93. Epub 2014 Aug 5.

AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Service de Neurologie 2-Mazarin, 47-83, Boulevard de l'Hôpital, 75013 Paris, France.

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http://www.tandfonline.com/doi/full/10.1586/14737159.2014.94
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http://dx.doi.org/10.1586/14737159.2014.945436DOI Listing
September 2014

Tumor and endothelial cell hybrids participate in glioblastoma vasculature.

Biomed Res Int 2014 24;2014:827327. Epub 2014 Apr 24.

Sorbonne Universités, UPMC, Université Paris 06, Inserm, CNRS, UM 75, U 1127, UMR 7225, ICM, 75013 Paris, France ; AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Service de Neurologie Mazarin, 75013 Paris, France.

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http://dx.doi.org/10.1155/2014/827327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017715PMC
November 2015

The cognitive spectrum in neurodegenerative Langerhans cell histiocytosis.

J Neurol 2014 Aug 22;261(8):1537-43. Epub 2014 May 22.

Service de Neurologie 2-Mazarin, AP-HP, Groupe Hospitalier Pitié-Salpêtrière, 47-83, Boulevard de l'Hôpital, 75013, Paris, France.

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http://dx.doi.org/10.1007/s00415-014-7375-yDOI Listing
August 2014

An ANOCEF genomic and transcriptomic microarray study of the response to irinotecan and bevacizumab in recurrent glioblastomas.

Biomed Res Int 2014 2;2014:282815. Epub 2014 Apr 2.

ANOCEF (Association des Neuro-Oncologues d'Expression Française (French Speaking NeuroOncologists' Association)), France ; Service de Neuro-oncologie, Hôpital Neurologique, Hospices Civils de Lyon, 59 Boulevard Pinel, 69394 Lyon Cedex 3, Lyon, France ; Université de Lyon, Claude Bernard Lyon 1, Lyon, France ; Lyon Neuroscience Research Center, INSERM U1028/CNRS UMR 5292, Lyon, France.

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http://dx.doi.org/10.1155/2014/282815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996912PMC
February 2015