Ahmad R Hariri

Ahmad R Hariri

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Ahmad R Hariri

Ahmad R Hariri

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A genome-wide association study-derived polygenic score for interleukin-1β is associated with hippocampal volume in two samples.

Hum Brain Mapp 2019 Sep 22;40(13):3910-3917. Epub 2019 May 22.

Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, North Carolina.

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http://dx.doi.org/10.1002/hbm.24639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679724PMC
September 2019

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.

Am J Hum Genet 2019 Aug;105(2):334-350

Division of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA; Department of Psychiatry, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY 11030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699140PMC
August 2019

Heightened amygdala reactivity and increased stress generation predict internalizing symptoms in adults following childhood maltreatment.

J Child Psychol Psychiatry 2019 Jul 1;60(7):752-761. Epub 2019 Apr 1.

Division of Psychology and Language Science, Department of Clinical Educational and Health Psychology, University College London, London, UK.

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http://dx.doi.org/10.1111/jcpp.13041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594878PMC
July 2019

Divergence of an association between depressive symptoms and a dopamine polygenic score in Caucasians and Asians.

Eur Arch Psychiatry Clin Neurosci 2019 Jul 9. Epub 2019 Jul 9.

Laboratory of NeuroGenetics, Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1007/s00406-019-01040-xDOI Listing
July 2019

Investigating patterns of neural response associated with childhood abuse v. childhood neglect - Corrigendum.

Psychol Med 2019 Jul 12. Epub 2019 Jul 12.

Division of Psychology and Language Sciences,University College London,26 Bedford Way,WC1H 0AP,London,UK.

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http://dx.doi.org/10.1017/S0033291719001752DOI Listing
July 2019

Genetic Risk for Rheumatoid Arthritis is Associated with Increased Striatal Volume in Healthy Young Adults.

Sci Rep 2019 Jul 29;9(1):10994. Epub 2019 Jul 29.

Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1038/s41598-019-47505-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662838PMC
July 2019

Investigating patterns of neural response associated with childhood abuse v. childhood neglect.

Psychol Med 2019 Jun 13:1-10. Epub 2019 Jun 13.

Division of Psychology and Language Sciences,University College London,26 Bedford Way, WC1H 0AP, London,UK.

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http://dx.doi.org/10.1017/S003329171900134XDOI Listing
June 2019

Microstructural integrity of white matter moderates an association between childhood adversity and adult trait anger.

Aggress Behav 2019 May 30;45(3):310-318. Epub 2019 Jan 30.

Laboratory of NeuroGenetics, Department of Psychology and Neuroscience, Duke University, Durham, North Carolina.

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http://dx.doi.org/10.1002/ab.21820DOI Listing
May 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Authors:
Gail Davies Max Lam Sarah E Harris Joey W Trampush Michelle Luciano W David Hill Saskia P Hagenaars Stuart J Ritchie Riccardo E Marioni Chloe Fawns-Ritchie David C M Liewald Judith A Okely Ari V Ahola-Olli Catriona L K Barnes Lars Bertram Joshua C Bis Katherine E Burdick Andrea Christoforou Pamela DeRosse Srdjan Djurovic Thomas Espeseth Stella Giakoumaki Sudheer Giddaluru Daniel E Gustavson Caroline Hayward Edith Hofer M Arfan Ikram Robert Karlsson Emma Knowles Jari Lahti Markus Leber Shuo Li Karen A Mather Ingrid Melle Derek Morris Christopher Oldmeadow Teemu Palviainen Antony Payton Raha Pazoki Katja Petrovic Chandra A Reynolds Muralidharan Sargurupremraj Markus Scholz Jennifer A Smith Albert V Smith Natalie Terzikhan Anbupalam Thalamuthu Stella Trompet Sven J van der Lee Erin B Ware B Gwen Windham Margaret J Wright Jingyun Yang Jin Yu David Ames Najaf Amin Philippe Amouyel Ole A Andreassen Nicola J Armstrong Amelia A Assareh John R Attia Deborah Attix Dimitrios Avramopoulos David A Bennett Anne C Böhmer Patricia A Boyle Henry Brodaty Harry Campbell Tyrone D Cannon Elizabeth T Cirulli Eliza Congdon Emily Drabant Conley Janie Corley Simon R Cox Anders M Dale Abbas Dehghan Danielle Dick Dwight Dickinson Johan G Eriksson Evangelos Evangelou Jessica D Faul Ian Ford Nelson A Freimer He Gao Ina Giegling Nathan A Gillespie Scott D Gordon Rebecca F Gottesman Michael E Griswold Vilmundur Gudnason Tamara B Harris Annette M Hartmann Alex Hatzimanolis Gerardo Heiss Elizabeth G Holliday Peter K Joshi Mika Kähönen Sharon L R Kardia Ida Karlsson Luca Kleineidam David S Knopman Nicole A Kochan Bettina Konte John B Kwok Stephanie Le Hellard Teresa Lee Terho Lehtimäki Shu-Chen Li Christina M Lill Tian Liu Marisa Koini Edythe London Will T Longstreth Oscar L Lopez Anu Loukola Tobias Luck Astri J Lundervold Anders Lundquist Leo-Pekka Lyytikäinen Nicholas G Martin Grant W Montgomery Alison D Murray Anna C Need Raymond Noordam Lars Nyberg William Ollier Goran Papenberg Alison Pattie Ozren Polasek Russell A Poldrack Bruce M Psaty Simone Reppermund Steffi G Riedel-Heller Richard J Rose Jerome I Rotter Panos Roussos Suvi P Rovio Yasaman Saba Fred W Sabb Perminder S Sachdev Claudia L Satizabal Matthias Schmid Rodney J Scott Matthew A Scult Jeannette Simino P Eline Slagboom Nikolaos Smyrnis Aïcha Soumaré Nikos C Stefanis David J Stott Richard E Straub Kjetil Sundet Adele M Taylor Kent D Taylor Ioanna Tzoulaki Christophe Tzourio André Uitterlinden Veronique Vitart Aristotle N Voineskos Jaakko Kaprio Michael Wagner Holger Wagner Leonie Weinhold K Hoyan Wen Elisabeth Widen Qiong Yang Wei Zhao Hieab H H Adams Dan E Arking Robert M Bilder Panos Bitsios Eric Boerwinkle Ornit Chiba-Falek Aiden Corvin Philip L De Jager Stéphanie Debette Gary Donohoe Paul Elliott Annette L Fitzpatrick Michael Gill David C Glahn Sara Hägg Narelle K Hansell Ahmad R Hariri M Kamran Ikram J Wouter Jukema Eero Vuoksimaa Matthew C Keller William S Kremen Lenore Launer Ulman Lindenberger Aarno Palotie Nancy L Pedersen Neil Pendleton David J Porteous Katri Räikkönen Olli T Raitakari Alfredo Ramirez Ivar Reinvang Igor Rudan Dan Rujescu Reinhold Schmidt Helena Schmidt Peter W Schofield Peter R Schofield John M Starr Vidar M Steen Julian N Trollor Steven T Turner Cornelia M Van Duijn Arno Villringer Daniel R Weinberger David R Weir James F Wilson Anil Malhotra Andrew M McIntosh Catharine R Gale Sudha Seshadri Thomas H Mosley Jan Bressler Todd Lencz Ian J Deary

Nat Commun 2019 May 1;10(1):2068. Epub 2019 May 1.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1038/s41467-019-10160-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494826PMC
May 2019

The Emerging Importance of the Cerebellum in Broad Risk for Psychopathology.

Authors:
Ahmad R Hariri

Neuron 2019 Apr;102(1):17-20

Laboratory of NeuroGenetics, Department of Psychology and Neuroscience, Duke University, Durham, NC 27708, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.02.031DOI Listing
April 2019

Prefrontal Executive Control Rescues Risk for Anxiety Associated with High Threat and Low Reward Brain Function.

Cereb Cortex 2019 Jan;29(1):70-76

Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1093/cercor/bhx304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6490969PMC
January 2019

Subclinical eating disorder traits are correlated with cortical thickness in regions associated with food reward and perception.

Brain Imaging Behav 2019 Jan 8. Epub 2019 Jan 8.

Laboratory of NeuroGenetics, Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.

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http://link.springer.com/10.1007/s11682-018-0007-x
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http://dx.doi.org/10.1007/s11682-018-0007-xDOI Listing
January 2019

Primary and Secondary Variants of Psychopathy in a Volunteer Sample Are Associated With Different Neurocognitive Mechanisms.

Biol Psychiatry Cogn Neurosci Neuroimaging 2018 12 12;3(12):1013-1021. Epub 2018 Apr 12.

Developmental Risk and Resilience Unit, Division of Psychology and Language Sciences, University College London, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S24519022183008
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http://dx.doi.org/10.1016/j.bpsc.2018.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185817PMC
December 2018

Emotion Regulation and the Experience of Future Negative Mood: The Importance of Assessing Social Support.

Front Psychol 2018 20;9:2287. Epub 2018 Nov 20.

Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, NC, United States.

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http://dx.doi.org/10.3389/fpsyg.2018.02287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255934PMC
November 2018

A Connectome-wide Functional Signature of Transdiagnostic Risk for Mental Illness.

Biol Psychiatry 2018 09 10;84(6):452-459. Epub 2018 Apr 10.

Laboratory of NeuroGenetics, Department of Psychology and Neuroscience, Duke University, Durham, North Carolina.

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http://dx.doi.org/10.1016/j.biopsych.2018.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119080PMC
September 2018

Trajectories of Alcohol Initiation and Use During Adolescence: The Role of Stress and Amygdala Reactivity.

J Am Acad Child Adolesc Psychiatry 2018 08 18;57(8):550-560. Epub 2018 Jun 18.

Duke University, the Durham Veterans Affairs Medical Center, Durham, NC, and the University of Texas Health at San Antonio.

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http://dx.doi.org/10.1016/j.jaac.2018.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396321PMC
August 2018

Replication in Imaging Genetics: The Case of Threat-Related Amygdala Reactivity.

Biol Psychiatry 2018 07 16;84(2):148-159. Epub 2017 Nov 16.

Laboratory of NeuroGenetics, Department of Psychology and Neuroscience, Duke University, Durham, North Carolina.

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http://dx.doi.org/10.1016/j.biopsych.2017.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955809PMC
July 2018

A Link Between Childhood Adversity and Trait Anger Reflects Relative Activity of the Amygdala and Dorsolateral Prefrontal Cortex.

Biol Psychiatry Cogn Neurosci Neuroimaging 2018 07 21;3(7):644-649. Epub 2018 Mar 21.

Laboratory of NeuroGenetics, Department of Psychology and Neuroscience, Duke University, Durham, North Carolina.

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http://dx.doi.org/10.1016/j.bpsc.2018.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062443PMC
July 2018

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

Authors:
Jeanne E Savage Philip R Jansen Sven Stringer Kyoko Watanabe Julien Bryois Christiaan A de Leeuw Mats Nagel Swapnil Awasthi Peter B Barr Jonathan R I Coleman Katrina L Grasby Anke R Hammerschlag Jakob A Kaminski Robert Karlsson Eva Krapohl Max Lam Marianne Nygaard Chandra A Reynolds Joey W Trampush Hannah Young Delilah Zabaneh Sara Hägg Narelle K Hansell Ida K Karlsson Sten Linnarsson Grant W Montgomery Ana B Muñoz-Manchado Erin B Quinlan Gunter Schumann Nathan G Skene Bradley T Webb Tonya White Dan E Arking Dimitrios Avramopoulos Robert M Bilder Panos Bitsios Katherine E Burdick Tyrone D Cannon Ornit Chiba-Falek Andrea Christoforou Elizabeth T Cirulli Eliza Congdon Aiden Corvin Gail Davies Ian J Deary Pamela DeRosse Dwight Dickinson Srdjan Djurovic Gary Donohoe Emily Drabant Conley Johan G Eriksson Thomas Espeseth Nelson A Freimer Stella Giakoumaki Ina Giegling Michael Gill David C Glahn Ahmad R Hariri Alex Hatzimanolis Matthew C Keller Emma Knowles Deborah Koltai Bettina Konte Jari Lahti Stephanie Le Hellard Todd Lencz David C Liewald Edythe London Astri J Lundervold Anil K Malhotra Ingrid Melle Derek Morris Anna C Need William Ollier Aarno Palotie Antony Payton Neil Pendleton Russell A Poldrack Katri Räikkönen Ivar Reinvang Panos Roussos Dan Rujescu Fred W Sabb Matthew A Scult Olav B Smeland Nikolaos Smyrnis John M Starr Vidar M Steen Nikos C Stefanis Richard E Straub Kjetil Sundet Henning Tiemeier Aristotle N Voineskos Daniel R Weinberger Elisabeth Widen Jin Yu Goncalo Abecasis Ole A Andreassen Gerome Breen Lene Christiansen Birgit Debrabant Danielle M Dick Andreas Heinz Jens Hjerling-Leffler M Arfan Ikram Kenneth S Kendler Nicholas G Martin Sarah E Medland Nancy L Pedersen Robert Plomin Tinca J C Polderman Stephan Ripke Sophie van der Sluis Patrick F Sullivan Scott I Vrieze Margaret J Wright Danielle Posthuma

Nat Genet 2018 07 25;50(7):912-919. Epub 2018 Jun 25.

Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41588-018-0152-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411041PMC
July 2018

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Authors:
Gail Davies Max Lam Sarah E Harris Joey W Trampush Michelle Luciano W David Hill Saskia P Hagenaars Stuart J Ritchie Riccardo E Marioni Chloe Fawns-Ritchie David C M Liewald Judith A Okely Ari V Ahola-Olli Catriona L K Barnes Lars Bertram Joshua C Bis Katherine E Burdick Andrea Christoforou Pamela DeRosse Srdjan Djurovic Thomas Espeseth Stella Giakoumaki Sudheer Giddaluru Daniel E Gustavson Caroline Hayward Edith Hofer M Arfan Ikram Robert Karlsson Emma Knowles Jari Lahti Markus Leber Shuo Li Karen A Mather Ingrid Melle Derek Morris Christopher Oldmeadow Teemu Palviainen Antony Payton Raha Pazoki Katja Petrovic Chandra A Reynolds Muralidharan Sargurupremraj Markus Scholz Jennifer A Smith Albert V Smith Natalie Terzikhan Anbupalam Thalamuthu Stella Trompet Sven J van der Lee Erin B Ware B Gwen Windham Margaret J Wright Jingyun Yang Jin Yu David Ames Najaf Amin Philippe Amouyel Ole A Andreassen Nicola J Armstrong Amelia A Assareh John R Attia Deborah Attix Dimitrios Avramopoulos David A Bennett Anne C Böhmer Patricia A Boyle Henry Brodaty Harry Campbell Tyrone D Cannon Elizabeth T Cirulli Eliza Congdon Emily Drabant Conley Janie Corley Simon R Cox Anders M Dale Abbas Dehghan Danielle Dick Dwight Dickinson Johan G Eriksson Evangelos Evangelou Jessica D Faul Ian Ford Nelson A Freimer He Gao Ina Giegling Nathan A Gillespie Scott D Gordon Rebecca F Gottesman Michael E Griswold Vilmundur Gudnason Tamara B Harris Annette M Hartmann Alex Hatzimanolis Gerardo Heiss Elizabeth G Holliday Peter K Joshi Mika Kähönen Sharon L R Kardia Ida Karlsson Luca Kleineidam David S Knopman Nicole A Kochan Bettina Konte John B Kwok Stephanie Le Hellard Teresa Lee Terho Lehtimäki Shu-Chen Li Christina M Lill Tian Liu Marisa Koini Edythe London Will T Longstreth Oscar L Lopez Anu Loukola Tobias Luck Astri J Lundervold Anders Lundquist Leo-Pekka Lyytikäinen Nicholas G Martin Grant W Montgomery Alison D Murray Anna C Need Raymond Noordam Lars Nyberg William Ollier Goran Papenberg Alison Pattie Ozren Polasek Russell A Poldrack Bruce M Psaty Simone Reppermund Steffi G Riedel-Heller Richard J Rose Jerome I Rotter Panos Roussos Suvi P Rovio Yasaman Saba Fred W Sabb Perminder S Sachdev Claudia L Satizabal Matthias Schmid Rodney J Scott Matthew A Scult Jeannette Simino P Eline Slagboom Nikolaos Smyrnis Aïcha Soumaré Nikos C Stefanis David J Stott Richard E Straub Kjetil Sundet Adele M Taylor Kent D Taylor Ioanna Tzoulaki Christophe Tzourio André Uitterlinden Veronique Vitart Aristotle N Voineskos Jaakko Kaprio Michael Wagner Holger Wagner Leonie Weinhold K Hoyan Wen Elisabeth Widen Qiong Yang Wei Zhao Hieab H H Adams Dan E Arking Robert M Bilder Panos Bitsios Eric Boerwinkle Ornit Chiba-Falek Aiden Corvin Philip L De Jager Stéphanie Debette Gary Donohoe Paul Elliott Annette L Fitzpatrick Michael Gill David C Glahn Sara Hägg Narelle K Hansell Ahmad R Hariri M Kamran Ikram J Wouter Jukema Eero Vuoksimaa Matthew C Keller William S Kremen Lenore Launer Ulman Lindenberger Aarno Palotie Nancy L Pedersen Neil Pendleton David J Porteous Katri Räikkönen Olli T Raitakari Alfredo Ramirez Ivar Reinvang Igor Rudan Dan Rujescu Reinhold Schmidt Helena Schmidt Peter W Schofield Peter R Schofield John M Starr Vidar M Steen Julian N Trollor Steven T Turner Cornelia M Van Duijn Arno Villringer Daniel R Weinberger David R Weir James F Wilson Anil Malhotra Andrew M McIntosh Catharine R Gale Sudha Seshadri Thomas H Mosley Jan Bressler Todd Lencz Ian J Deary

Nat Commun 2018 05 29;9(1):2098. Epub 2018 May 29.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1038/s41467-018-04362-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974083PMC
May 2018

A BRIEF INTRODUCTION TO THE NEUROGENETICS OF COGNITION-EMOTION INTERACTIONS.

Curr Opin Behav Sci 2018 Feb 15;19:50-54. Epub 2017 Oct 15.

Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, NC, 27708, USA.

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http://dx.doi.org/10.1016/j.cobeha.2017.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790152PMC
February 2018

Post-secondary maternal education buffers against neural risk for psychological vulnerability to future life stress.

Neuropsychologia 2018 01 12;109:134-139. Epub 2017 Dec 12.

Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, NC 27708, USA.

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http://dx.doi.org/10.1016/j.neuropsychologia.2017.12.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801164PMC
January 2018

Building Bridges through Science.

Authors:
Thomas Lissek Michelle Adams John Adelman Ehud Ahissar Mohammed Akaaboune Huda Akil Mustafa al'Absi Fazal Arain Juan Carlos Arango-Lasprilla Deniz Atasoy Jesus Avila Ashraf Badawi Hilmar Bading Abdul Mannan Baig Jimena Baleriola Carlos Belmonte Ilaria Bertocchi Heinrich Betz Colin Blakemore Olaf Blanke Philipp Boehm-Sturm Tobias Bonhoeffer Paolo Bonifazi Nils Brose Patrizia Campolongo Tansu Celikel Cathy C Chang Ta-Yuan Chang Ami Citri Hollis T Cline Jesus M Cortes Kathleen Cullen Kellie Dean José M Delgado-Garcia Mathieu Desroches John F Disterhoft John E Dowling Andreas Draguhn Sherif F El-Khamisy Abdeljabbar El Manira S Ather Enam Juan M Encinas Asier Erramuzpe José A Esteban Isabel Fariñas Edmond Fischer Izumi Fukunaga Iñigo Gabilondo Detlev Ganten Albert Gidon Juan Carlos Gomez-Esteban Paul Greengard Valery Grinevich Agnés Gruart Roger Guillemin Ahmad R Hariri Bassem Hassan Michael Häusser Yasunori Hayashi Natasha K Hussain Adnan Abdul Jabbar Mohamed Jaber Reinhardt Jahn Essam Mohammed Janahi Mohamed Kabbaj Helmut Kettenmann Merel Kindt Shira Knafo Georg Köhr Shoji Komai Harm Krugers Bernd Kuhn Nouria Lakhdar Ghazal Matthew E Larkum Mickey London Beat Lutz Carlos Matute Luis Martinez-Millan Mouna Maroun James McGaugh Ahmed A Moustafa Anwar Nasim Klaus-Armin Nave Erwin Neher Karoly Nikolich Tiago Outeiro Lucy M Palmer Olga Penagarikano Isabel Perez-Otano Donald W Pfaff Bruno Poucet Atta-Ur Rahman Pedro Ramos-Cabrer Ali Rashidy-Pour Richard J Roberts Serafim Rodrigues Joshua R Sanes Andreas T Schaefer Menahem Segal Idan Segev Saad Shafqat Nikhat Ahmed Siddiqui Hermona Soreq Eduardo Soriano-García Rainer Spanagel Rolf Sprengel Greg Stuart Thomas C Südhof Jan Tønnesen Mario Treviño Basim M Uthman J Craig Venter Alexei Verkhratsky Craig Weiss Torsten N Wiesel Emre Yaksi Ofer Yizhar Larry J Young Paul Young Nasser H Zawia José L Zugaza Mazahir T Hasan

Neuron 2017 Nov;96(4):730-735

Achucarro Basque Center for Neuroscience, 48940 Leioa, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.09.028DOI Listing
November 2017

Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.

Cell Rep 2017 Nov;21(9):2597-2613

Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA; Department of Psychiatry, Hofstra Northwell School of Medicine, Hempstead, NY, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.11.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789458PMC
November 2017

Reward-Related Ventral Striatum Activity Buffers against the Experience of Depressive Symptoms Associated with Sleep Disturbances.

J Neurosci 2017 10 18;37(40):9724-9729. Epub 2017 Sep 18.

Laboratory of NeuroGenetics, Department of Psychology and Neuroscience, Duke University, Durham, North Carolina 27705, and.

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http://www.jneurosci.org/lookup/doi/10.1523/JNEUROSCI.1734-1
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http://dx.doi.org/10.1523/JNEUROSCI.1734-17.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628412PMC
October 2017

The long reach of early adversity: Parenting, stress, and neural pathways to antisocial behavior in adulthood.

Biol Psychiatry Cogn Neurosci Neuroimaging 2017 Oct 27;2(7):582-590. Epub 2017 Jun 27.

Department of Psychology, University of Michigan, Ann Arbor, MI.

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http://dx.doi.org/10.1016/j.bpsc.2017.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695704PMC
October 2017

Neurogenetic plasticity and sex influence the link between corticolimbic structural connectivity and trait anxiety.

Sci Rep 2017 09 8;7(1):10959. Epub 2017 Sep 8.

Laboratory of NeuroGenetics, Department of Psychology and Neuroscience, Duke University, Durham, NC, 27708, USA.

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http://www.nature.com/articles/s41598-017-11497-2
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http://dx.doi.org/10.1038/s41598-017-11497-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591318PMC
September 2017

Individual differences in regulatory focus predict neural response to reward.

Soc Neurosci 2017 08 30;12(4):419-429. Epub 2016 Apr 30.

a Department of Psychology & Neuroscience , Duke University , Durham , NC , USA.

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http://dx.doi.org/10.1080/17470919.2016.1178170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662473PMC
August 2017

Imaging Genetics and Genomics in Psychiatry: A Critical Review of Progress and Potential.

Biol Psychiatry 2017 08 13;82(3):165-175. Epub 2017 Jan 13.

Laboratory of Neurogenetics, Intramural Research Program, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland.

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http://dx.doi.org/10.1016/j.biopsych.2016.12.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505787PMC
August 2017

An earlier time of scan is associated with greater threat-related amygdala reactivity.

Soc Cogn Affect Neurosci 2017 08;12(8):1272-1283

BRAIN Laboratory, Department of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO 63130, USA.

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http://dx.doi.org/10.1093/scan/nsx057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597858PMC
August 2017

Hypothalamic-pituitary-adrenal axis genetic variation and early stress moderates amygdala function.

Psychoneuroendocrinology 2017 Jun 12;80:170-178. Epub 2017 Mar 12.

BRAIN Lab, Department of Psychology, Washington University in St. Louis, St. Louis, MO, USA; Neurosciences Program, Division of Biology and Biomedical Sciences, Washington University in St. Louis, St. Louis, MO, USA; Molecular Genetics and Genomics Program, Division of Biology and Biomedical Sciences, Washington University in St. Louis, St. Louis, MO, USA; Human and Statistical Genetics Program, Division of Biology and Biomedical Sciences, Washington University in St. Louis, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.psyneuen.2017.03.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685810PMC
June 2017

Thinking and Feeling: Individual Differences in Habitual Emotion Regulation and Stress-Related Mood are Associated with Prefrontal Executive Control.

Clin Psychol Sci 2017 6;5(1):150-157. Epub 2016 Oct 6.

Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, NC, 27708, USA.

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http://dx.doi.org/10.1177/2167702616654688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298870PMC
October 2016

Amygdala reactivity predicts adolescent antisocial behavior but not callous-unemotional traits.

Dev Cogn Neurosci 2017 04 27;24:84-92. Epub 2017 Feb 27.

Department of Psychiatry & Behavioral Sciences, Duke University, 417 Chapel Drive, Durham, NC 27708, USA; Durham VA Medical Center, 508 Fulton St, Durham, NC 27705, USA.

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http://dx.doi.org/10.1016/j.dcn.2017.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429212PMC
April 2017

Reward-related ventral striatum activity links polygenic risk for attention-deficit/hyperactivity disorder to problematic alcohol use in young adulthood.

Biol Psychiatry Cogn Neurosci Neuroimaging 2017 Mar;2(2):180-187

Washington University in St. Louis, Department of Psychological and Brain Sciences, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1016/j.bpsc.2016.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560771PMC
March 2017

A Common Polymorphism in a Williams Syndrome Gene Predicts Amygdala Reactivity and Extraversion in Healthy Adults.

Biol Psychiatry 2017 02 15;81(3):203-210. Epub 2015 Dec 15.

Laboratory of Neurogenetics, Department of Psychology and Neuroscience, Duke University, Durham, North Carolina.

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http://dx.doi.org/10.1016/j.biopsych.2015.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909599PMC
February 2017

An epigenetic mechanism links socioeconomic status to changes in depression-related brain function in high-risk adolescents.

Mol Psychiatry 2017 02 24;22(2):209-214. Epub 2016 May 24.

Division of Translational Neuroscience, Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC 27708 USA.

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http://dx.doi.org/10.1038/mp.2016.82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122474PMC
February 2017

Peering into the brain to predict behavior: Peer-reported, but not self-reported, conscientiousness links threat-related amygdala activity to future problem drinking.

Neuroimage 2017 02 5;146:894-903. Epub 2016 Oct 5.

Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, NC 27708, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2016.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321841PMC
February 2017

A Functional Interleukin-18 Haplotype Predicts Depression and Anxiety through Increased Threat-Related Amygdala Reactivity in Women but Not Men.

Neuropsychopharmacology 2017 01 19;42(2):419-426. Epub 2016 Jul 19.

Laboratory of NeuroGenetics, Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1038/npp.2016.129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399226PMC
January 2017

Cultural influences on neural basis of inhibitory control.

Neuroimage 2016 Oct 2;139:114-126. Epub 2016 Jun 2.

Department of Psychology and Interdepartmental Neuroscience Program, Northwestern University, Evanston, IL, United States; International Cultural Neuroscience Consortium, Highland Park, IL, United States. Electronic address:

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October 2016

Can we identify meaningful epigenetic effects on human brain function and related risk for mental illness?

Epigenomics 2016 10 7;8(10):1307-1310. Epub 2016 Sep 7.

Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, NC 27708, USA.

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http://dx.doi.org/10.2217/epi-2016-0099DOI Listing
October 2016

Thinking and Feeling: Individual Differences in Habitual Emotion Regulation and Stress-Related Mood are Associated with Prefrontal Executive Control.

Clin Psychol Sci 2017 6;5(1):150-157. Epub 2016 Oct 6.

Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, NC, 27708, USA.

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http://dx.doi.org/10.1177/2167702616654688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298870PMC
October 2016

Decoding Spontaneous Emotional States in the Human Brain.

PLoS Biol 2016 09 14;14(9):e2000106. Epub 2016 Sep 14.

Department of Psychology & Neuroscience, Duke University, Durham, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.pbio.2000106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023171PMC
September 2016

An oxytocin receptor polymorphism predicts amygdala reactivity and antisocial behavior in men.

Soc Cogn Affect Neurosci 2016 08 1;11(8):1218-26. Epub 2016 Apr 1.

Department of Psychology, University of Michigan, Ann Arbor, USA

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http://dx.doi.org/10.1093/scan/nsw042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967804PMC
August 2016

Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research.

Biol Psychiatry 2016 07;80(2):84-86

Department of Psychiatry, University Neuropsychiatric Institute, University of Utah Health Sciences Center, Salt Lake City, Utah.

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http://dx.doi.org/10.1016/j.biopsych.2016.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150945PMC
July 2016

Variability in emotional responsiveness and coping style during active avoidance as a window onto psychological vulnerability to stress.

Physiol Behav 2016 May 26;158:90-9. Epub 2016 Feb 26.

Department of Psychology & Neuroscience, Duke University, Durham, NC 27708, USA.

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http://dx.doi.org/10.1016/j.physbeh.2016.02.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995782PMC
May 2016

Dissecting the role of amygdala reactivity in antisocial behavior in a sample of young, low-income, urban men.

Clin Psychol Sci 2016 May 14;4(3):527-544. Epub 2015 Dec 14.

Department of Psychology, University of Pittsburgh, Pittsburgh, PA ; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA ; Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1177/2167702615614511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941820PMC
May 2016

PER1 rs3027172 Genotype Interacts with Early Life Stress to Predict Problematic Alcohol Use, but Not Reward-Related Ventral Striatum Activity.

Front Psychol 2016 31;7:464. Epub 2016 Mar 31.

Brain Laboratory, Department of Psychological and Brain Sciences, Washington University in St. LouisSt. Louis, MO, USA; Division of Biology and Biomedical Sciences, Washington University in St. LouisSt. Louis, MO, USA; Department of Psychiatry, Washington University in St. LouisSt. Louis, MO, USA.

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http://dx.doi.org/10.3389/fpsyg.2016.00464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814479PMC
April 2016

Cumulative stress in childhood is associated with blunted reward-related brain activity in adulthood.

Soc Cogn Affect Neurosci 2016 Mar 5;11(3):405-12. Epub 2015 Oct 5.

Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1093/scan/nsv124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769626PMC
March 2016

Genetic Moderation of Stress Effects on Corticolimbic Circuitry.

Neuropsychopharmacology 2016 Jan 20;41(1):275-96. Epub 2015 Jul 20.

Department of Psychology and Neuroscience, Laboratory of NeuroGenetics, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1038/npp.2015.216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677127PMC
January 2016

Blunted Ventral Striatum Development in Adolescence Reflects Emotional Neglect and Predicts Depressive Symptoms.

Biol Psychiatry 2015 Nov 27;78(9):598-605. Epub 2015 May 27.

Department of Psychiatry, University of Texas Health Sciences Center at San Antonio, San Antonio, Texas; South Texas Veterans Health Care System, San Antonio, Texas.

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http://dx.doi.org/10.1016/j.biopsych.2015.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593720PMC
November 2015

Finding translation in stress research.

Nat Neurosci 2015 Oct 25;18(10):1347-52. Epub 2015 Sep 25.

Laboratory of Behavioral and Genomic Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, Maryland, USA.

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http://dx.doi.org/10.1038/nn.4111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693288PMC
October 2015

FRAS1-related extracellular matrix 3 (FREM3) single-nucleotide polymorphism effects on gene expression, amygdala reactivity and perceptual processing speed: An accelerated aging pathway of depression risk.

Front Psychol 2015 16;6:1377. Epub 2015 Sep 16.

Campbell Family Mental Health Research Institute of CAMH Toronto, ON, Canada ; Department of Psychiatry, University of Pittsburgh Pittsburgh, PA, USA ; Department of Psychiatry, Department of Pharmacology and Toxicology, University of Toronto Toronto, ON, Canada.

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http://dx.doi.org/10.3389/fpsyg.2015.01377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584966PMC
October 2015

Can we observe epigenetic effects on human brain function?

Trends Cogn Sci 2015 Jul 4;19(7):366-73. Epub 2015 Jun 4.

Laboratory of NeuroGenetics, Department of Psychology and Neuroscience, Duke University, Durham, NC 27708, USA.

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http://dx.doi.org/10.1016/j.tics.2015.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486509PMC
July 2015

Anterior cingulate cortex gray matter volume mediates an association between 2D:4D ratio and trait aggression in women but not men.

Psychoneuroendocrinology 2015 Jun 10;56:148-56. Epub 2015 Mar 10.

Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, NC 27708, USA.

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http://dx.doi.org/10.1016/j.psyneuen.2015.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410779PMC
June 2015

Differential patterns of amygdala and ventral striatum activation predict gender-specific changes in sexual risk behavior.

J Neurosci 2015 Jun;35(23):8896-900

Laboratory of NeuroGenetics, Department of Psychology and Neuroscience, Duke University, Durham, North Carolina 27708-0086.

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http://dx.doi.org/10.1523/JNEUROSCI.0737-15.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461692PMC
June 2015

Basal forebrain moderates the magnitude of task-dependent amygdala functional connectivity.

Soc Cogn Affect Neurosci 2015 Apr 19;10(4):501-7. Epub 2014 May 19.

Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Institute for Genome Sciences & Policy, Duke University, Durham, 27708 NC, USA.

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http://dx.doi.org/10.1093/scan/nsu080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381234PMC
April 2015

Developmental change in amygdala reactivity during adolescence: effects of family history of depression and stressful life events.

Am J Psychiatry 2015 Mar 19;172(3):276-83. Epub 2014 Dec 19.

From the Center for Developmental Science, University of North Carolina at Chapel Hill; the Department of Psychology and Neuroscience and the Institute for Genome Sciences and Policy, Duke University, Durham, N.C.; and the Translational Epidemiology Program, Department of Psychiatry, University of Texas Health Sciences Center at San Antonio.

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http://dx.doi.org/10.1176/appi.ajp.2014.14020195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452289PMC
March 2015

A neural biomarker of psychological vulnerability to future life stress.

Neuron 2015 Feb;85(3):505-11

Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, NC 27708, USA.

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http://dx.doi.org/10.1016/j.neuron.2014.12.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319095PMC
February 2015

Testosterone responses to competition predict decreased trust ratings of emotionally neutral faces.

Psychoneuroendocrinology 2014 Nov 19;49:79-83. Epub 2014 Jun 19.

Department of Psychology and Neuroscience, Duke University, Durham, NC, United States.

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http://dx.doi.org/10.1016/j.psyneuen.2014.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700816PMC
November 2014

Reduced hippocampal and medial prefrontal gray matter mediate the association between reported childhood maltreatment and trait anxiety in adulthood and predict sensitivity to future life stress.

Biol Mood Anxiety Disord 2014 13;4:12. Epub 2014 Nov 13.

Laboratory of NeuroGenetics, Department of Psychology and Neuroscience, Duke University, 417 Chapel Drive, Durham, NC 27708, USA.

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http://dx.doi.org/10.1186/2045-5380-4-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236295PMC
November 2014

Feature-based representations of emotional facial expressions in the human amygdala.

Soc Cogn Affect Neurosci 2014 Sep 24;9(9):1372-8. Epub 2013 Jul 24.

Center for Cognitive Neuroscience, Department of Psychology and Neuroscience, Laboratory of NeuroGenetics, and Institute for Genome Sciences and Policy, Duke University, Durham, NC 27708, USA Center for Cognitive Neuroscience, Department of Psychology and Neuroscience, Laboratory of NeuroGenetics, and Institute for Genome Sciences and Policy, Duke University, Durham, NC 27708, USA.

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http://dx.doi.org/10.1093/scan/nst112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158364PMC
September 2014

Beyond genotype: serotonin transporter epigenetic modification predicts human brain function.

Nat Neurosci 2014 Sep 3;17(9):1153-5. Epub 2014 Aug 3.

Laboratory of NeuroGenetics, Department of Psychology &Neuroscience, and Institute for Genome Sciences &Policy, Duke University, Durham, North Carolina, USA.

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http://dx.doi.org/10.1038/nn.3778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146649PMC
September 2014

Testosterone rapidly increases neural reactivity to threat in healthy men: a novel two-step pharmacological challenge paradigm.

Biol Psychiatry 2014 Aug 29;76(4):324-31. Epub 2014 Jan 29.

Department of Psychology, Wayne State University, Detroit, Michigan; Department of Psychology, Nipissing University, North Bay, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2014.01.016DOI Listing
August 2014

Convergent effects of mouse Pet-1 deletion and human PET-1 variation on amygdala fear and threat processing.

Exp Neurol 2013 Dec 4;250:260-9. Epub 2013 Oct 4.

Department of Psychological and Brain Sciences, Center for the Integrative Study of Animal Behavior, Indiana University, Bloomington, IN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2013.09.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932627PMC
December 2013

Identifying serotonergic mechanisms underlying the corticolimbic response to threat in humans.

Philos Trans R Soc Lond B Biol Sci 2013 25;368(1615):20120192. Epub 2013 Feb 25.

Center for Integrated Molecular Brain Imaging, University of Copenhagen, Copenhagen 2100, Denmark.

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http://dx.doi.org/10.1098/rstb.2012.0192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638383PMC
September 2013

Uncinate fasciculus fractional anisotropy correlates with typical use of reappraisal in women but not men.

Emotion 2013 Jun 11;13(3):385-390. Epub 2013 Feb 11.

Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Institute for Genome Sciences & Policy, Duke University.

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http://dx.doi.org/10.1037/a0031163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094171PMC
June 2013

Impact of sleep quality on amygdala reactivity, negative affect, and perceived stress.

Psychosom Med 2013 May 16;75(4):350-8. Epub 2013 Apr 16.

Department of Psychiatry, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1097/PSY.0b013e31828ef15bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747835PMC
May 2013

Genetic moderation of the association between regulatory focus and reward responsiveness: a proof-of-concept study.

Biol Mood Anxiety Disord 2013 Feb 1;3(1). Epub 2013 Feb 1.

Department of Psychology & Neuroscience, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1186/2045-5380-3-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570330PMC
February 2013

Neural embedding of stress reactivity.

Nat Neurosci 2012 Dec;15(12):1605-7

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http://dx.doi.org/10.1038/nn.3270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700823PMC
December 2012

Sleep quality and neural circuit function supporting emotion regulation.

Biol Mood Anxiety Disord 2012 Dec 7;2:22. Epub 2012 Dec 7.

Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, 417 Chapel Dr,, Durham, NC 27708, USA.

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http://dx.doi.org/10.1186/2045-5380-2-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542038PMC
December 2012

Neural responses to threat and reward interact to predict stress-related problem drinking: A novel protective role of the amygdala.

Biol Mood Anxiety Disord 2012 Nov 14;2:19. Epub 2012 Nov 14.

Laboratory of NeuroGenetics, Department of Psychology & Neuroscience and Institute for Genome Sciences & Policy, Duke University, NC 27708, Durham, USA.

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http://dx.doi.org/10.1186/2045-5380-2-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502334PMC
November 2012