Dr Ahmad Ali, PhD - University of Mumbai - Assistant Professor

Dr Ahmad Ali

PhD

University of Mumbai

Assistant Professor

Mumbai, Maharashtra | India

Main Specialties: Biotechnology

Additional Specialties: Biochemistry, Molecular Biology

ORCID logohttps://orcid.org/0000-0003-4467-5387


Top Author

Dr Ahmad Ali, PhD - University of Mumbai - Assistant Professor

Dr Ahmad Ali

PhD

Introduction

My laboratory is working on the characterization of the process of Glycation. This process begins with an interaction between the carbonyl group of sugars and amino group of other biomolecules. It results in generation of many harmful products which are commonly called as advanced glycation end products (AGEs). These products have been implicated in various pathophysiological conditions such as diabetes, Alzheimer's, Parkinson's, cardiovascular etc. The complications are due to the structural alteration of DNA and proteins. Researchers have been trying to understand the mechanism of formation of glycation products. There have been also efforts to prevent the accumulation of AGEs. Some drugs have been successfully launched to prevent the formation of these harmful compounds.

Primary Affiliation: University of Mumbai - Mumbai, Maharashtra , India

Specialties:

Additional Specialties:

Research Interests:


View Dr Ahmad Ali’s Resume / CV

Education

Jan 2003 - Mar 2007
University of Mumbai
PhD
Department of Life Sciences
Jul 1996 - Jun 1998
Jamia Hamdard
M. Sc. Biochemistry
Department of Biochemistry
Jul 1993 - Jul 1996
Aligarh Muslim University Faculty of Life Sciences
B. Sc. (Hons.)
Biohcemistry

Experience

Sep 2012 - Sep 2012
University of Mumbai
Assistant Professor
Department of Life Sciences
Jun 2010 - Aug 2012
National Institute of Pharmaceutical Education and Research Hajipur
Assistant Professor/Lecturer
Department of Biotechnology
Jun 2007 - Jun 2010
Thakur College of Science & Commerce
Assistant Professor/Lecturer
Department of Biotechnology

Publications

2Publications

94Reads

597Profile Views

Dietary phytonutrients in prevention of diabetes related complications.

Curr Diabetes Rev 2019 09 6. Epub 2019 Sep 6.

Department of Life Sciences, University of Mumbai, Vidyanagari, Santacruz (East), Mumbai, Maharashtra, India.

Background: The increasing prevalence of reported cases of diabetes has evidently become a major global public health concern. Although, diabetes management is possible by the administration of synthetic anti-diabetic agents, there are profound side-effects associated with their long-term usage. Hence there is a demand for safer alternatives which could be possibly formulated using specific yet common phytonutrients.

Objectives: The main objective of this review is to describe the cellular mechanisms of phytonutrients as an alternative to commercially available synthetic anti-diabetic agents in the management of diabetes and related complications. Furthermore, the clinical evidence that supports this view is also highlighted.

Methodology: An in-depth review of published literature was carried out to identify the most promising phytonutrients in the management of diabetes and related complications.

Results: A number of phytonutrients are reported to be potential anti-diabetic agents. Few examples include biguanides, resveratrol, lycopene, thymoquinone and quercetin. However, suitable formulations using these phytonutrients and their clinical trials are still underway. Most of the reported findings focus on one aspect of several biochemical processes e.g. enhancement of glucose utilization, anti-oxidation, induction of insulin production, antiglycation etc. An in-depth study of phytonutrients with respect to functional, immunological as well as biochemical factors suggesting their efficacy, as well as safety in the management of diabetes, is rarely reported.

Conclusion: Our study thus highlights the abundance of clinical evidence of the efficiency of phytonutrients, and at the same time, the scarcity of clinically approved and marketed phytonutrients, as drugs, for the management of diabetes and related complications.

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http://dx.doi.org/10.2174/1573399815666190906151319DOI Listing
September 2019
76 Reads

Antiglycating potential of acesulfame potassium: an artificial sweetener.

Appl Physiol Nutr Metab 2017 Oct 15;42(10):1054-1063. Epub 2017 Jun 15.

University Department of Life Sciences, University of Mumbai, Vidyanagari, Santacruz (E), Mumbai 400098, India.

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http://dx.doi.org/10.1139/apnm-2017-0119DOI Listing
October 2017
18 Reads
2.225 Impact Factor

Top co-authors

Ali Ahmad
Ali Ahmad

University of Montreal

11
Keith D Lindor
Keith D Lindor

Mayo Clinic

7
Elizabeth J Carey
Elizabeth J Carey

Mayo Clinic

6
Ponnandai Somasundar
Ponnandai Somasundar

West Virginia University

3
Jean-Pierre Routy
Jean-Pierre Routy

McGill University Health Centre

3
Ali Aldosari
Ali Aldosari

King Saud University

2
Vikram Mehraj
Vikram Mehraj

McGill University Health Centre

2
Suzanne Samarani
Suzanne Samarani

University of Montreal

2