Agnieszka B Bialkowska

Agnieszka B Bialkowska

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Agnieszka B Bialkowska

Agnieszka B Bialkowska

Publications by authors named "Agnieszka B Bialkowska"

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The Novel Small-Molecule SR18662 Efficiently Inhibits the Growth of Colorectal Cancer and .

Mol Cancer Ther 2019 11 29;18(11):1973-1984. Epub 2019 Jul 29.

Department of Medicine, Stony Brook University School of Medicine, Stony Brook, New York.

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http://dx.doi.org/10.1158/1535-7163.MCT-18-1366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825545PMC
November 2019

Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells.

Cell Mol Gastroenterol Hepatol 2019 Nov 25;9(4):587-609. Epub 2019 Nov 25.

Department of Medicine, Stony Brook University Renaissance School of Medicine, Stony Brook, New York; Department of Physiology and Biophysics, Stony Brook University Renaissance School of Medicine, Stony Brook, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jcmgh.2019.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078555PMC
November 2019

Increased Genetic Instability and Accelerated Progression of Colitis-Associated Colorectal Cancer through Intestinal Epithelium-specific Deletion of .

Mol Cancer Res 2019 01 14;17(1):165-176. Epub 2018 Aug 14.

Department of Medicine, Stony Brook University School of Medicine, Stony Brook, New York.

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http://dx.doi.org/10.1158/1541-7786.MCR-18-0399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318049PMC
January 2019

Krüppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar-to-Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice.

Gastroenterology 2018 04 15;154(5):1494-1508.e13. Epub 2017 Dec 15.

Department of Medicine, Stony Brook University School of Medicine, Stony Brook, New York. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880723PMC
April 2018

KLF5 mediates the hyper-proliferative phenotype of the intestinal epithelium in mice with intestine-specific endogenous K-Ras expression.

Am J Cancer Res 2018 1;8(4):723-731. Epub 2018 Apr 1.

Department of Medicine, School of Medicine, Stony Brook University, Stony Brook NY 11794, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934562PMC
April 2018

Correction to: The Role of Intestinal Stem Cells in Epithelial Regeneration Following Radiation-Induced Gut Injury.

Curr Stem Cell Rep 2018;4(1):95. Epub 2018 Feb 19.

1Department of Medicine, Stony Brook University School of Medicine, HSC T-17, Rm. 090, Stony Brook, NY 11794 USA.

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http://dx.doi.org/10.1007/s40778-018-0121-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866267PMC
February 2018

Murine Model for Colitis-Associated Cancer of the Colon.

Methods Mol Biol 2016 ;1438:245-54

Department of Medicine, Stony Brook University, Stony Brook, NY, 11794, USA.

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http://dx.doi.org/10.1007/978-1-4939-3661-8_14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657253PMC
December 2017

The loss of Krüppel-like factor 15 in Foxd1 stromal cells exacerbates kidney fibrosis.

Kidney Int 2017 11 24;92(5):1178-1193. Epub 2017 Jun 24.

Kidney Institute of PLA, Department of Medicine, Changzheng Hospital, Second Military Medical University, Shanghai 200003, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2017.03.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651204PMC
November 2017

Krüppel-like factor 5 is essential for maintenance of barrier function in mouse colon.

Am J Physiol Gastrointest Liver Physiol 2017 Nov 1;313(5):G478-G491. Epub 2017 Sep 1.

Department of Medicine, Stony Brook University School of Medicine, Stony Brook, New York;

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http://dx.doi.org/10.1152/ajpgi.00172.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792213PMC
November 2017

The Role of Intestinal Stem Cells in Epithelial Regeneration Following Radiation-Induced Gut Injury.

Curr Stem Cell Rep 2017 5;3(4):320-332. Epub 2017 Oct 5.

1Department of Medicine, Stony Brook University School of Medicine, HSC T-17, Rm. 090, Stony Brook, NY 11794 USA.

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http://dx.doi.org/10.1007/s40778-017-0103-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818549PMC
October 2017

SP and KLF Transcription Factors in Digestive Physiology and Diseases.

Gastroenterology 2017 06 30;152(8):1845-1875. Epub 2017 Mar 30.

Department of Medicine, Stony Brook University School of Medicine, Stony Brook, New York; Department of Physiology and Biophysics, Stony Brook University School of Medicine, Stony Brook, New York. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.03.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815166PMC
June 2017

Novel sphingosine kinase-1 inhibitor, LCL351, reduces immune responses in murine DSS-induced colitis.

Prostaglandins Other Lipid Mediat 2017 05 2;130:47-56. Epub 2017 Apr 2.

Department of Medicine and the, Stony Brook Cancer Center, Stony Brook University, Stony Brook, NY, USA; Northport Veterans Affairs Medical Center, Northport, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.prostaglandins.2017.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509055PMC
May 2017

Krüppel-like factors in mammalian stem cells and development.

Development 2017 03;144(5):737-754

Division of Nephrology, Department of Medicine, Stony Brook University School of Medicine, Stony Brook, NY 11794-8176, USA

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http://dx.doi.org/10.1242/dev.145441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374354PMC
March 2017

Intestinal stem cell resurgence by enterocyte precursors.

Stem Cell Investig 2016 23;3:49. Epub 2016 Sep 23.

Department of Medicine, Stony Brook University School of Medicine, Stony Brook, NY, USA;; Department of Physiology and Biophysics, Stony Brook University School of Medicine, Stony Brook, NY, USA.

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http://dx.doi.org/10.21037/sci.2016.09.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067364PMC
September 2016

Improved Swiss-rolling Technique for Intestinal Tissue Preparation for Immunohistochemical and Immunofluorescent Analyses.

J Vis Exp 2016 07 13(113). Epub 2016 Jul 13.

Department of Medicine, Stony Brook University School of Medicine; Department of Physiology & Biophysics, Stony Brook University School of Medicine;

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http://dx.doi.org/10.3791/54161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993444PMC
July 2016

Krüppel-like Factor 4 Modulates Development of BMI1(+) Intestinal Stem Cell-Derived Lineage Following γ-Radiation-Induced Gut Injury in Mice.

Stem Cell Reports 2016 06 26;6(6):815-824. Epub 2016 May 26.

Department of Medicine, Stony Brook University, Stony Brook, NY 11794, USA; Stony Brook University Medical Center, HSC T-16, Room 020, Stony Brook, NY 11794-8160, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2016.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911500PMC
June 2016

KLF4 Suppresses Tumor Formation in Genetic and Pharmacological Mouse Models of Colonic Tumorigenesis.

Mol Cancer Res 2016 Apr 2;14(4):385-96. Epub 2016 Feb 2.

Department of Medicine, Stony Brook University, Stony Brook, New York. Department of Physiology and Biophysics, Stony Brook University, Stony Brook, New York.

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http://dx.doi.org/10.1158/1541-7786.MCR-15-0410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834227PMC
April 2016

Establishment of highly tumorigenic human colorectal cancer cell line (CR4) with properties of putative cancer stem cells.

PLoS One 2014 12;9(6):e99091. Epub 2014 Jun 12.

Department of Pathology, Stony Brook University Medical Center, Stony Brook, New York, United States of America; Institute of Chemical Biology and Drug Discovery, Stony Brook University, Stony Brook, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0099091PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055451PMC
October 2015

Krüppel-like factor 4 is a radioprotective factor for the intestine following γ-radiation-induced gut injury in mice.

Am J Physiol Gastrointest Liver Physiol 2015 Jan 20;308(2):G121-38. Epub 2014 Nov 20.

Department of Medicine, Stony Brook University, Stony Brook, New York; and

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http://dx.doi.org/10.1152/ajpgi.00080.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297857PMC
January 2015

Krüppel-like factor 5 is essential for proliferation and survival of mouse intestinal epithelial stem cells.

Stem Cell Res 2015 Jan 6;14(1):10-9. Epub 2014 Nov 6.

Department of Medicine, Stony Brook University School of Medicine, HSC-T16 Room 020, Stony Brook, NY 11794, United States. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2014.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310780PMC
January 2015

Role of Krüppel-like factor 5 in the maintenance of the stem cell niche in the intestinal crypt.

Stem Cell Transl Investig 2015;2(2)

Department of Medicine, Stony Brook University School of Medicine, HSC-T16 Room 020, Stony Brook, NY 11794, United States ; Department of Physiology and Biophysics, Stony Brook University School of Medicine, HSC-T16 Room 020, Stony Brook, NY 11794, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474380PMC
January 2015

Prostate cancer stem cell-targeted efficacy of a new-generation taxoid, SBT-1214 and novel polyenolic zinc-binding curcuminoid, CMC2.24.

PLoS One 2013 24;8(9):e69884. Epub 2013 Sep 24.

Department of Pathology, Stony Brook University Medical Center, Stony Brook, New York, United States of America ; Institute of Chemical Biology & Drug Development, Stony Brook University, Stony Brook, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0069884PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782470PMC
July 2014

Inducible intestine-specific deletion of Krüppel-like factor 5 is characterized by a regenerative response in adult mouse colon.

Dev Biol 2014 Mar 15;387(2):191-202. Epub 2014 Jan 15.

Department of Medicine, Stony Brook University School of Medicine, HSC-T16 Room 020, Stony Brook, NY 11794, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2014.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949508PMC
March 2014

Chemoprevention of familial adenomatous polyposis by bromo-noscapine (EM011) in the Apc(Min/+) mouse model.

Int J Cancer 2012 Sep 9;131(6):1435-44. Epub 2012 Feb 9.

Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1002/ijc.27344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362662PMC
September 2012

High-throughput screening strategies for targeted identification of therapeutic compounds in colorectal cancer.

Future Oncol 2012 Mar;8(3):259-72

Department of Medicine, Stony Brook University School of Medicine, HSC-T17 Room 090, Stony Brook, NY 11794, USA.

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http://dx.doi.org/10.2217/fon.12.19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425953PMC
March 2012

The E3 ubiquitin ligase SMAD ubiquitination regulatory factor 2 negatively regulates Krüppel-like factor 5 protein.

J Biol Chem 2011 Nov 27;286(46):40354-64. Epub 2011 Sep 27.

Division of Digestive Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1074/jbc.M111.258707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220560PMC
November 2011

Krüppel-like factor 5 protects against dextran sulfate sodium-induced colonic injury in mice by promoting epithelial repair.

Gastroenterology 2011 Feb 12;140(2):540-549.e2. Epub 2010 Nov 12.

Division of Digestive Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1053/j.gastro.2010.10.061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031670PMC
February 2011

Haploinsufficiency of Krüppel-like factor 5 rescues the tumor-initiating effect of the Apc(Min) mutation in the intestine.

Cancer Res 2009 May 12;69(10):4125-33. Epub 2009 May 12.

Division of Digestive Diseases, Department of Medicine, Department of Pharmacology, and Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-4402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702486PMC
May 2009

Identification of novel small-molecule compounds that inhibit the proproliferative Kruppel-like factor 5 in colorectal cancer cells by high-throughput screening.

Mol Cancer Ther 2009 Mar 24;8(3):563-70. Epub 2009 Feb 24.

Division of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 201 Whitehead Biomedical Research Building, 615 Michael Street, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-08-0767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727710PMC
March 2009

Notch inhibits expression of the Krüppel-like factor 4 tumor suppressor in the intestinal epithelium.

Mol Cancer Res 2008 Dec;6(12):1920-7

Division of Digestive Diseases, Department of Medicine, Emory University School of Medicine, 615 Michael Street, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-08-0224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628949PMC
December 2008

SUMOylation regulates nuclear localization of Krüppel-like factor 5.

J Biol Chem 2008 Nov 9;283(46):31991-2002. Epub 2008 Sep 9.

Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1074/jbc.M803612200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581587PMC
November 2008

Krüppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis.

Gastroenterology 2008 Jan 17;134(1):120-30. Epub 2007 Oct 17.

Division of Digestive Diseases, Department of Medicine, Emory University, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1053/j.gastro.2007.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194652PMC
January 2008