Agneta Siegbahn

Agneta Siegbahn

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Agneta Siegbahn

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Adipocytes express tissue factor and FVII and are procoagulant in a TF/FVIIa-dependent manner.

Ups J Med Sci 2019 Aug 13;124(3):158-167. Epub 2019 Aug 13.

Department of Medical Sciences, Clinical Chemistry, Uppsala University , Uppsala , Sweden.

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http://dx.doi.org/10.1080/03009734.2019.1645248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758637PMC
August 2019

Subsequent Event Risk in Individuals With Established Coronary Heart Disease.

Authors:
Riyaz S Patel Vinicius Tragante Amand F Schmidt Raymond O McCubrey Michael V Holmes Laurence J Howe Kenan Direk Axel Åkerblom Karin Leander Salim S Virani Karol A Kaminski Jochen D Muehlschlegel Hooman Allayee Peter Almgren Maris Alver Ekaterina V Baranova Hassan Behloui Bram Boeckx Peter S Braund Lutz P Breitling Graciela Delgado Nubia E Duarte Marie-Pierre Dubé Line Dufresne Niclas Eriksson Luisa Foco Markus Scholz Crystel M Gijsberts Charlotte Glinge Yan Gong Jaana Hartiala Mahyar Heydarpour Jaroslav A Hubacek Marcus Kleber Daniel Kofink Salma Kotti Pekka Kuukasjärvi Vei-Vei Lee Andreas Leiherer Petra A Lenzini Daniel Levin Leo-Pekka Lyytikäinen Nicola Martinelli Ute Mons Christopher P Nelson Kjell Nikus Anna P Pilbrow Rafal Ploski Yan V Sun Michael W T Tanck W H Wilson Tang Stella Trompet Sander W van der Laan Jessica Van Setten Ragnar O Vilmundarson Chiara Viviani Anselmi Efthymia Vlachopoulou Lawien Al Ali Eric Boerwinkle Carlo Briguori John F Carlquist Kathryn F Carruthers Gavino Casu John Deanfield Panos Deloukas Frank Dudbridge Thomas Engstrøm Natalie Fitzpatrick Kim Fox Bruna Gigante Stefan James Marja-Liisa Lokki Paulo A Lotufo Nicola Marziliano Ify R Mordi Joseph B Muhlestein Christopher Newton-Cheh Jan Pitha Christoph H Saely Ayman Samman-Tahhan Pratik B Sandesara Andrej Teren Adam Timmis Frans Van de Werf Els Wauters Arthur A M Wilde Ian Ford David J Stott Ale Algra Maria G Andreassi Diego Ardissino Benoit J Arsenault Christie M Ballantyne Thomas O Bergmeijer Connie R Bezzina Simon C Body Eric H Boersma Peter Bogaty Michiel L Bots Hermann Brenner Jasper J Brugts Ralph Burkhardt Clara Carpeggiani Gianluigi Condorelli Rhonda M Cooper-DeHoff Sharon Cresci Nicolas Danchin Ulf de Faire Robert N Doughty Heinz Drexel James C Engert Keith A A Fox Domenico Girelli Diederick E Grobbee Emil Hagström Stanley L Hazen Claes Held Harry Hemingway Imo E Hoefer G Kees Hovingh Reza Jabbari Julie A Johnson J Wouter Jukema Marcin P Kaczor Mika Kähönen Jiri Kettner Marek Kiliszek Olaf H Klungel Bo Lagerqvist Diether Lambrechts Jari O Laurikka Terho Lehtimäki Daniel Lindholm B K Mahmoodi Anke H Maitland-van der Zee Ruth McPherson Olle Melander Andres Metspalu Anna Niemcunowicz-Janica Oliviero Olivieri Grzegorz Opolski Colin N Palmer Gerard Pasterkamp Carl J Pepine Alexandre C Pereira Louise Pilote Arshed A Quyyumi A Mark Richards Marek Sanak Agneta Siegbahn Tabassome Simon Juha Sinisalo J Gustav Smith John A Spertus Steen Stender Alexandre F R Stewart Wojciech Szczeklik Anna Szpakowicz Jean-Claude Tardif Jurriën M Ten Berg Jacob Tfelt-Hansen George Thanassoulis Joachim Thiery Christian Torp-Pedersen Yolanda van der Graaf Frank L J Visseren Johannes Waltenberger Peter E Weeke Pim Van der Harst Chim C Lang Naveed Sattar Vicky A Cameron Jeffrey L Anderson James M Brophy Guillaume Pare Benjamin D Horne Winfried März Lars Wallentin Nilesh J Samani Aroon D Hingorani Folkert W Asselbergs

Circ Genom Precis Med 2019 Apr 21;12(4):e002470. Epub 2019 Mar 21.

Institute of Health Informatics (N.F., A. Timmis, H.H., F.W.A.), Faculty of Population Health Science, University College London, United Kingdom.

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http://dx.doi.org/10.1161/CIRCGEN.119.002470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629546PMC
April 2019

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.

Authors:
Riyaz S Patel Amand F Schmidt Vinicius Tragante Raymond O McCubrey Michael V Holmes Laurence J Howe Kenan Direk Axel Åkerblom Karin Leander Salim S Virani Karol A Kaminski Jochen D Muehlschlegel Marie-Pierre Dubé Hooman Allayee Peter Almgren Maris Alver Ekaterina V Baranova Hassan Behlouli Bram Boeckx Peter S Braund Lutz P Breitling Graciela Delgado Nubia E Duarte Line Dufresne Niclas Eriksson Luisa Foco Crystel M Gijsberts Yan Gong Jaana Hartiala Mahyar Heydarpour Jaroslav A Hubacek Marcus Kleber Daniel Kofink Pekka Kuukasjärvi Vei-Vei Lee Andreas Leiherer Petra A Lenzini Daniel Levin Leo-Pekka Lyytikäinen Nicola Martinelli Ute Mons Christopher P Nelson Kjell Nikus Anna P Pilbrow Rafal Ploski Yan V Sun Michael W T Tanck W H Wilson Tang Stella Trompet Sander W van der Laan Jessica van Setten Ragnar O Vilmundarson Chiara Viviani Anselmi Efthymia Vlachopoulou Eric Boerwinkle Carlo Briguori John F Carlquist Kathryn F Carruthers Gavino Casu John Deanfield Panos Deloukas Frank Dudbridge Natalie Fitzpatrick Bruna Gigante Stefan James Marja-Liisa Lokki Paulo A Lotufo Nicola Marziliano Ify R Mordi Joseph B Muhlestein Chris Newton Cheh Jan Pitha Christoph H Saely Ayman Samman-Tahhan Pratik B Sandesara Andrej Teren Adam Timmis Frans Van de Werf Els Wauters Arthur A M Wilde Ian Ford David J Stott Ale Algra Maria G Andreassi Diego Ardissino Benoit J Arsenault Christie M Ballantyne Thomas O Bergmeijer Connie R Bezzina Simon C Body Peter Bogaty Gert J de Borst Hermann Brenner Ralph Burkhardt Clara Carpeggiani Gianluigi Condorelli Rhonda M Cooper-DeHoff Sharon Cresci Ulf de Faire Robert N Doughty Heinz Drexel James C Engert Keith A A Fox Domenico Girelli Emil Hagström Stanley L Hazen Claes Held Harry Hemingway Imo E Hoefer G Kees Hovingh Julie A Johnson Pim A de Jong J Wouter Jukema Marcin P Kaczor Mika Kähönen Jiri Kettner Marek Kiliszek Olaf H Klungel Bo Lagerqvist Diether Lambrechts Jari O Laurikka Terho Lehtimäki Daniel Lindholm Bakhtawar K Mahmoodi Anke H Maitland-van der Zee Ruth McPherson Olle Melander Andres Metspalu Witold Pepinski Oliviero Olivieri Grzegorz Opolski Colin N Palmer Gerard Pasterkamp Carl J Pepine Alexandre C Pereira Louise Pilote Arshed A Quyyumi A Mark Richards Marek Sanak Markus Scholz Agneta Siegbahn Juha Sinisalo J Gustav Smith John A Spertus Alexandre F R Stewart Wojciech Szczeklik Anna Szpakowicz Jurriën M Ten Berg George Thanassoulis Joachim Thiery Yolanda van der Graaf Frank L J Visseren Johannes Waltenberger Pim Van der Harst Jean-Claude Tardif Naveed Sattar Chim C Lang Guillaume Pare James M Brophy Jeffrey L Anderson Winfried März Lars Wallentin Vicky A Cameron Benjamin D Horne Nilesh J Samani Aroon D Hingorani Folkert W Asselbergs

Circ Genom Precis Med 2019 Apr 21;12(4):e002471. Epub 2019 Mar 21.

Institute of Cardiovascular Science, Faculty of Population Health Science (R.S.P., A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A.).

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http://dx.doi.org/10.1161/CIRCGEN.119.002471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625876PMC
April 2019

Proteomic Biomarkers for Incident Aortic Stenosis Requiring Valvular Replacement.

Circulation 2018 08;138(6):590-599

Departments of Public Health and Clinical Medicine (J.L., A.H., B.J., U.N., S.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.030414DOI Listing
August 2018

Sensitive and Specific Detection of Platelet-Derived and Tissue Factor-Positive Extracellular Vesicles in Plasma Using Solid-Phase Proximity Ligation Assay.

TH Open 2018 Jul 27;2(3):e250-e260. Epub 2018 Jul 27.

Department of Medical Sciences, Clinical Chemistry and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1055/s-0038-1667204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602879PMC
July 2018

Fibrin clot properties independently predict adverse clinical outcome following acute coronary syndrome: a PLATO substudy.

Eur Heart J 2018 04;39(13):1078-1085

Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK.

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http://dx.doi.org/10.1093/eurheartj/ehy013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019045PMC
April 2018

Methylation-based estimated biological age and cardiovascular disease.

Eur J Clin Invest 2018 Feb 27;48(2). Epub 2017 Dec 27.

Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1111/eci.12872DOI Listing
February 2018

Carotid Endarterectomy Induces the Release of Inflammatory Markers and the Activation of Coagulation as Measured in the Jugular Bulb.

J Stroke Cerebrovasc Dis 2017 Oct 23;26(10):2320-2328. Epub 2017 Jun 23.

Department of Surgical Sciences, Uppsala University Hospital, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S10523057173023
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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.05.020DOI Listing
October 2017

Associations between tooth loss and prognostic biomarkers and the risk for cardiovascular events in patients with stable coronary heart disease.

Int J Cardiol 2017 Oct 17;245:271-276. Epub 2017 Jul 17.

Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden; Uppsala Clinical Research Center (UCR), Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.ijcard.2017.07.036DOI Listing
October 2017

GDF-15 and TRAIL-R2 are powerful predictors of long-term mortality in patients with acute myocardial infarction.

Eur J Prev Cardiol 2017 10 1;24(15):1576-1583. Epub 2017 Aug 1.

2 Region Västmanland - Uppsala University, Centre for Clinical Research, Hospital of Västmanland Västerås, Sweden.

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http://dx.doi.org/10.1177/2047487317725017DOI Listing
October 2017

Antiplatelet Agents for the Treatment and Prevention of Coronary Atherothrombosis.

J Am Coll Cardiol 2017 Oct;70(14):1760-1776

Cardiovascular Science Institute-ICCC IIB-Sant Pau, CiberCV, Hospital de Sant Pau, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.jacc.2017.08.037DOI Listing
October 2017

Growth-differentiation factor 15 and risk of major bleeding in atrial fibrillation: Insights from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial.

Am Heart J 2017 Aug 6;190:94-103. Epub 2017 Jun 6.

Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.ahj.2017.06.001DOI Listing
August 2017

Microparticles during long-term follow-up after acute myocardial infarction. Association to atherosclerotic burden and risk of cardiovascular events.

Thromb Haemost 2017 07 20;117(8):1571-1581. Epub 2017 Apr 20.

Christina Christersson, MD, PhD, Department of Medical Sciences, Cardiology, Uppsala University, SE 75185 Uppsala, Sweden, Tel.: +46 18 611 9068, E-mail:

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http://dx.doi.org/10.1160/TH16-11-0837DOI Listing
July 2017

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.

Authors:
Stephen Zewinger Marcus E Kleber Vinicius Tragante Raymond O McCubrey Amand F Schmidt Kenan Direk Ulrich Laufs Christian Werner Wolfgang Koenig Dietrich Rothenbacher Ute Mons Lutz P Breitling Herrmann Brenner Richard T Jennings Ioannis Petrakis Sarah Triem Mira Klug Alexandra Filips Stefan Blankenberg Christoph Waldeyer Christoph Sinning Renate B Schnabel Karl J Lackner Efthymia Vlachopoulou Ottar Nygård Gard Frodahl Tveitevåg Svingen Eva Ringdal Pedersen Grethe S Tell Juha Sinisalo Markku S Nieminen Reijo Laaksonen Stella Trompet Roelof A J Smit Naveed Sattar J Wouter Jukema Heinrich V Groesdonk Graciela Delgado Tatjana Stojakovic Anna P Pilbrow Vicky A Cameron A Mark Richards Robert N Doughty Yan Gong Rhonda Cooper-DeHoff Julie Johnson Markus Scholz Frank Beutner Joachim Thiery J Gustav Smith Ragnar O Vilmundarson Ruth McPherson Alexandre F R Stewart Sharon Cresci Petra A Lenzini John A Spertus Oliviero Olivieri Domenico Girelli Nicola I Martinelli Andreas Leiherer Christoph H Saely Heinz Drexel Axel Mündlein Peter S Braund Christopher P Nelson Nilesh J Samani Daniel Kofink Imo E Hoefer Gerard Pasterkamp Arshed A Quyyumi Yi-An Ko Jaana A Hartiala Hooman Allayee W H Wilson Tang Stanley L Hazen Niclas Eriksson Claes Held Emil Hagström Lars Wallentin Axel Åkerblom Agneta Siegbahn Igor Karp Christopher Labos Louise Pilote James C Engert James M Brophy George Thanassoulis Peter Bogaty Wojciech Szczeklik Marcin Kaczor Marek Sanak Salim S Virani Christie M Ballantyne Vei-Vei Lee Eric Boerwinkle Michael V Holmes Benjamin D Horne Aroon Hingorani Folkert W Asselbergs Riyaz S Patel Bernhard K Krämer Hubert Scharnagl Danilo Fliser Winfried März Thimoteus Speer

Lancet Diabetes Endocrinol 2017 07 26;5(7):534-543. Epub 2017 May 26.

Department of Internal Medicine IV, Saarland University Hospital, Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/S2213-8587(17)30096-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651679PMC
July 2017

IL-33 stimulates the release of procoagulant microvesicles from human monocytes and differentially increases tissue factor in human monocyte subsets.

Thromb Haemost 2017 06 11;117(7):1379-1390. Epub 2017 May 11.

Johann Wojta, Department of Internal Medicine II and Core Facilities, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria, Telephone: +43 1 40400/73500, Fax: +43 1 40400/73587, E-mail: or, Agneta Siegbahn, Department of Medical Sciences, Clinical Chemistry and Science for Life Laboratory, University Hospital and Uppsala University, SE 751 85 Uppsala, Sweden, Tel.: +46 18 611 4251, Fax: +46 18 552562, E-mail:

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http://www.thieme-connect.de/DOI/DOI?10.1160/TH16-10-0784
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http://dx.doi.org/10.1160/TH16-10-0784DOI Listing
June 2017

How to use D-dimer in acute cardiovascular care.

Eur Heart J Acute Cardiovasc Care 2017 Feb 22;6(1):69-80. Epub 2016 Sep 22.

12 Department of Medical Sciences, Uppsala University, Sweden.

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http://dx.doi.org/10.1177/2048872615610870DOI Listing
February 2017

Impact of physical activity on cardiovascular status in obesity.

Eur J Clin Invest 2017 Feb;47(2):167-175

Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden.

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http://dx.doi.org/10.1111/eci.12722DOI Listing
February 2017

Application of Biomarkers for Risk Stratification in Patients with Atrial Fibrillation.

Clin Chem 2017 Jan 3;63(1):152-164. Epub 2016 Nov 3.

Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden.

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http://clinchem.aaccjnls.org/content/clinchem/63/1/152.full.
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http://dx.doi.org/10.1373/clinchem.2016.255182DOI Listing
January 2017

Performance and Validation of a Novel Biomarker-Based Stroke Risk Score for Atrial Fibrillation.

Circulation 2016 Nov 28;134(22):1697-1707. Epub 2016 Aug 28.

From Department of Medical Sciences, Cardiology, Uppsala University, Sweden (J.O., Z.H., L.W.); Uppsala Clinical Research Center, Uppsala University, Sweden (J.O., Z.H., J.L., A.S., L.W.); Duke Clinical Research Institute, Duke Medicine, Durham, NC (J.H.A., C.B.G., R.D.L.); Population Health Research Institute, Hamilton, Canada (S.J.C., J.W.E., S.Y.); Thomas Jefferson Medical College and the Heart Center, Wynnewood, PA (M.D.E.); Boston University Medical Center, MA (E.M.H.); and Department of Medical Sciences, Clinical Chemistry, Uppsala University, Sweden (A.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.022802DOI Listing
November 2016

A stromal cell population in the large intestine identified by tissue factor expression that is lost during colorectal cancer progression.

Thromb Haemost 2016 Nov 22;116(6):1050-1059. Epub 2016 Sep 22.

Agneta Siegbahn, Department of Medical Sciences, Clinical Chemistry, University Hospital, Entr. 61, 3rd floor, S-751 85 Uppsala, Sweden, Tel.: +46 186114251, Fax: +46 18552562, E-mail:

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http://dx.doi.org/10.1160/TH16-04-0267DOI Listing
November 2016

The ABC risk score for patients with atrial fibrillation - Authors' reply.

Lancet 2016 Oct;388(10055):1980-1981

Department of Medical Sciences, Cardiology, Uppsala University, S-751 85 Uppsala, Sweden; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1016/S0140-6736(16)31462-3DOI Listing
October 2016

The composition and daily variation of microparticles in whole blood in stable coronary artery disease.

Scand J Clin Lab Invest 2016 25;76(1):25-32. Epub 2015 Sep 25.

c Department of Medical Sciences , Clinical Chemistry, Uppsala University , Uppsala , Sweden.

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http://www.tandfonline.com/doi/full/10.3109/00365513.2015.10
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http://dx.doi.org/10.3109/00365513.2015.1086928DOI Listing
September 2016

Circulating cell-derived microparticles as biomarkers in cardiovascular disease.

Biomark Med 2016 Sep 2;10(9):1009-22. Epub 2016 Sep 2.

Department of Medical Sciences, Clinical Chemistry, Uppsala University, Sweden.

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http://dx.doi.org/10.2217/bmm-2016-0035DOI Listing
September 2016

The novel biomarker-based ABC (age, biomarkers, clinical history)-bleeding risk score for patients with atrial fibrillation: a derivation and validation study.

Lancet 2016 Jun 4;387(10035):2302-2311. Epub 2016 Apr 4.

Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1016/S0140-6736(16)00741-8DOI Listing
June 2016

D-dimer and factor VIIa in atrial fibrillation - prognostic values for cardiovascular events and effects of anticoagulation therapy. A RE-LY substudy.

Thromb Haemost 2016 05 28;115(5):921-30. Epub 2016 Jan 28.

Prof. Agneta Siegbahn, Department of Medical Sciences, Clinical Chemistry, University Hospital, 751 85 Uppsala, Sweden, Tel.: +46 18 611 42 51, Fax: +46 18 55 25 62, E-mail:

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http://dx.doi.org/10.1160/TH15-07-0529DOI Listing
May 2016

The ABC (age, biomarkers, clinical history) stroke risk score: a biomarker-based risk score for predicting stroke in atrial fibrillation.

Eur Heart J 2016 May 25;37(20):1582-90. Epub 2016 Feb 25.

Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden Uppsala Clinical Research Center, Uppsala University, Uppsala Science Park, Uppsala, Sweden.

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http://dx.doi.org/10.1093/eurheartj/ehw054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875560PMC
May 2016

Cross-talk between the Tissue Factor/coagulation factor VIIa complex and the tyrosine kinase receptor EphA2 in cancer.

BMC Cancer 2016 05 31;16:341. Epub 2016 May 31.

Department of Medical Sciences, Clinical Chemistry & Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1186/s12885-016-2375-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888641PMC
May 2016

Growth differentiation factor-15 level predicts major bleeding and cardiovascular events in patients with acute coronary syndromes: results from the PLATO study.

Eur Heart J 2016 Apr 28;37(16):1325-33. Epub 2015 Sep 28.

Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden Uppsala Clinical Research Center, Uppsala, Sweden.

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http://dx.doi.org/10.1093/eurheartj/ehv491DOI Listing
April 2016

Biomarkers of inflammation and risk of cardiovascular events in anticoagulated patients with atrial fibrillation.

Heart 2016 Apr 2;102(7):508-17. Epub 2016 Feb 2.

Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1136/heartjnl-2015-308887DOI Listing
April 2016

Dabigatran etexilate and reduction in serum apolipoprotein B.

Heart 2016 Jan 9;102(1):57-62. Epub 2015 Nov 9.

Department of Medical Sciences, Uppsala Clinical Research Centre, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1136/heartjnl-2015-307586DOI Listing
January 2016

Associations between circulating proteins and corresponding genes expressed in coronary thrombi in patients with acute myocardial infarction.

Thromb Res 2015 Dec 8;136(6):1240-4. Epub 2015 Oct 8.

Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, Oslo, Norway; Faculty of Medicine, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1016/j.thromres.2015.10.005DOI Listing
December 2015

Discovery of New Risk Markers for Ischemic Stroke Using a Novel Targeted Proteomics Chip.

Stroke 2015 Dec 5;46(12):3340-7. Epub 2015 Nov 5.

From the Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden.

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http://dx.doi.org/10.1161/STROKEAHA.115.010829DOI Listing
December 2015

Interleukin-6 and C-reactive protein and risk for death and cardiovascular events in patients with atrial fibrillation.

Am Heart J 2015 Dec 3;170(6):1151-60. Epub 2015 Oct 3.

Uppsala Clinical Research Center and Department of Medical Sciences, Cardiology, Uppsala University, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ahj.2015.09.018DOI Listing
December 2015

Tissue factor/factor VIIa signalling promotes cytokine-induced beta cell death and impairs glucose-stimulated insulin secretion from human pancreatic islets.

Diabetologia 2015 Nov 14;58(11):2563-72. Epub 2015 Aug 14.

Department of Medical Sciences, Clinical Chemistry, Science for Life Laboratory, University Hospital, Uppsala University, Entr. 61 3rd floor, S-751 85, Uppsala, Sweden.

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http://dx.doi.org/10.1007/s00125-015-3729-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589554PMC
November 2015

Tissue Factor Noncoagulant Signaling: Mechanisms and Implications for Cell Migration and Apoptosis.

Semin Thromb Hemost 2015 Oct 29;41(7):691-9. Epub 2015 Sep 29.

Department of Medical Sciences, Clinical Chemistry, Uppsala University, Uppsala, Sweden.

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https://www.thieme-connect.com/products/ejournals/pdf/10.105
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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0035-1564046
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http://dx.doi.org/10.1055/s-0035-1564046DOI Listing
October 2015

Use of a proximity extension assay proteomics chip to discover new biomarkers for human atherosclerosis.

Atherosclerosis 2015 Sep 14;242(1):205-10. Epub 2015 Jul 14.

Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2015.07.023DOI Listing
September 2015

Effect of genetic variations on ticagrelor plasma levels and clinical outcomes.

Eur Heart J 2015 Aug 2;36(29):1901-12. Epub 2015 May 2.

Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden Uppsala Clinical Research Center, Uppsala University, Dag Hammarskjölds väg 14B, level 1, SE-751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1093/eurheartj/ehv116DOI Listing
August 2015

High plasma levels of heparin-binding epidermal growth factor are associated with a more stable plaque phenotype and reduced incidence of coronary events.

Arterioscler Thromb Vasc Biol 2015 Jan 30;35(1):222-8. Epub 2014 Oct 30.

From the Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden (S.R., M.W., H.B., G.N.F., B.H., E.B., A.S., A.E., P.D., H.G., I.G., J.N.); Department of Cardiology-Coronary diseases, Skåne University Hospital, Malmö, Sweden (A.S., A.E., I.G.); and Department of Medical Sciences, Clinical Chemistry and Science for Life Laboratory, Uppsala University, Uppsala, Sweden (A.S.).

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http://dx.doi.org/10.1161/ATVBAHA.114.304369DOI Listing
January 2015

Large-scale metabolomic profiling identifies novel biomarkers for incident coronary heart disease.

PLoS Genet 2014 Dec 11;10(12):e1004801. Epub 2014 Dec 11.

Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1004801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263376PMC
December 2014

The Eph tyrosine kinase receptors EphB2 and EphA2 are novel proteolytic substrates of tissue factor/coagulation factor VIIa.

J Biol Chem 2014 Nov 3;289(47):32379-91. Epub 2014 Oct 3.

From the Department of Medical Sciences, Clinical Chemistry, Uppsala University Hospital, SE-751 85 Uppsala, Science for Life Laboratory, Uppsala University, Sweden

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http://dx.doi.org/10.1074/jbc.M114.599332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239594PMC
November 2014

Growth differentiation factor 15, a marker of oxidative stress and inflammation, for risk assessment in patients with atrial fibrillation: insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial.

Circulation 2014 Nov 7;130(21):1847-58. Epub 2014 Oct 7.

From the Department of Medical Sciences, Cardiology (L.W., Z.H.), Department of Medical Sciences, Cardiovascular Epidemiology (S.A.), and Department of Medical Sciences, Clinical Chemistry (A.S.), and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden (L.W., Z.H.); Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden (U.A.); Duke University, Medical Center, Durham, NC (J.H.A., R.D.L., C.B.G.); Gabriele d'Annunzio University, Chieti, and Gabriele Monasterio Foundation, Pisa, Italy (R.D.C.); Bristol-Myers Squibb, Princeton, NJ (M.H.); University of Adelaide, Adelaide, Australia (J.D.H.); and Boston University Medical Center, Boston, MA (E.M.H.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.011204DOI Listing
November 2014

GDF-15 for prognostication of cardiovascular and cancer morbidity and mortality in men.

PLoS One 2013 2;8(12):e78797. Epub 2013 Dec 2.

Uppsala Clinical Research Center (UCR) and Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846468PMC
August 2014

Importance of persistent elevation of cardiac biomarkers in atrial fibrillation: a RE-LY substudy.

Heart 2014 Aug 2;100(15):1193-200. Epub 2014 May 2.

Department of Cardiology, Uppsala Clinical Research Center and Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1136/heartjnl-2013-304872DOI Listing
August 2014

Polymorphism of the cystatin C gene in patients with acute coronary syndromes: Results from the PLATelet inhibition and patient Outcomes study.

Am Heart J 2014 Jul 4;168(1):96-102.e2. Epub 2014 Apr 4.

Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden.

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July 2014

Tissue factor/factor VIIa induces cell survival and gene transcription by transactivation of the insulin-like growth factor 1 receptor.

Thromb Haemost 2014 Apr 12;111(4):748-60. Epub 2013 Dec 12.

Prof. Agneta Siegbahn, MD, PhD, FESC, Department of Medical Sciences, Clinical Chemistry and Science for Life Laboratory, University Hospital, Entr. 61 3rd floor, S-751 85 Uppsala, Sweden, E-mail: Tel.: +46 186114251, Fax: +46 18552562.

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April 2014

Efficacy and safety of dabigatran compared with warfarin in relation to baseline renal function in patients with atrial fibrillation: a RE-LY (Randomized Evaluation of Long-term Anticoagulation Therapy) trial analysis.

Circulation 2014 Mar 9;129(9):961-70. Epub 2013 Dec 9.

From Uppsala Clinical Research Center (Z.H., J.O., U.A., A.S., L.W.), Department of Medical Sciences, Cardiology (Z.H., J.O., L.W.), and Department of Medical Sciences, Clinical Chemistry (A.S.), Uppsala University, Sweden; Department of Cardiology, J.W. Goethe University, Frankfurt, Germany (S.H.H.); Population Health Research Institute, Hamilton, Ontario, Canada (S.J.C., J.W.E., S.Y.); Thomas Jefferson Medical College and the Heart Center, Wynnewood, PA (M.D.E.); and Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT (P.A.R.).

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March 2014

High-sensitivity troponin I for risk assessment in patients with atrial fibrillation: insights from the Apixaban for Reduction in Stroke and other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial.

Circulation 2014 Feb 13;129(6):625-34. Epub 2013 Nov 13.

Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden (Z.H., A.S., U.A., L.W.); Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden (Z.H., U.A., L.W.); Department of Medical Sciences, Clinical Chemistry, Uppsala University, Uppsala, Sweden (A.S.); Duke University, Medical Center, Durham, NC (C.B.G., J.H.A., R.D.L.); Department of Cardiology, Oslo University Hospital and Faculty of Medicine, Institute for Clinical Medicine, University of Oslo, Oslo, Norway (D.A.); Mayo Clinic College of Medicine, Rochester, MN (B.J.G.); Bristol-Myers Squibb, Princeton, NJ (P.M.); Division of Emergency Care, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland (V.-P.H.); University of Adelaide, Adelaide, Australia (J.H.); Medical Department, Hospital Unit West, Herning/Holstbro, Denmark (S.H.); Boston University Medical Center, Boston, MA (E.M.H.); and BHF Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland, United Kingdom (J.J.V.M.).

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February 2014

Identification of novel downstream molecules of tissue factor activation by comparative proteomic analysis.

J Proteome Res 2014 Feb 11;13(2):477-88. Epub 2013 Dec 11.

Department of Medical Sciences, Clinical Chemistry and Science for Life Laboratory, Uppsala University , 751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1021/pr4006298DOI Listing
February 2014

Biomarkers in relation to the effects of ticagrelor in comparison with clopidogrel in non-ST-elevation acute coronary syndrome patients managed with or without in-hospital revascularization: a substudy from the Prospective Randomized Platelet Inhibition and Patient Outcomes (PLATO) trial.

Circulation 2014 Jan 29;129(3):293-303. Epub 2013 Oct 29.

Department of Medical Sciences, Cardiology and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden (L.W., D.L., L.W., C.H., S.K.J.); Department of Medical Sciences, Clinical Chemistry and Uppsala Clinical Research Center Uppsala University, Uppsala, Sweden (A.S.); Division of Cardiovascular Health and Disease, Heart, Lung and Vascular Institute, Academic Health Center, Cincinnati, OH (R.C.B.); Department of Medicine, Stanford University, Stanford, CA (R.A.H., K.W.M.); TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (C.P.C.); Department of Cardiology, Medisch Centrum Alkmaar, Alkmaar, Netherlands (J.H.C.); AstraZeneca Research and Development, Mölndal, Sweden (A.H.); Medizinische Klinik, Universitätsklinikum Heidelberg, Heidelberg, Germany (E.G., H.A.K.); Medical Department, Hospital Unit West, Herning/Holstbro, Denmark (S.H.); INSERM-Unité 698, Paris, France; Assistance Publique-Hôpitaux de Paris, Département Hospitalo-Universitaire FIRE, Hôpital Bichat, Paris, France; Université Paris-Diderot, Sorbonne-Paris Cité, Paris, France; NHLI Imperial College, ICMS, Royal Brompton Hospital, London, UK (P.G.S.); and Department of Cardiovascular Science, University of Sheffield, Sheffield, UK (R.F.S.).

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January 2014

Common variants associated with plasma triglycerides and risk for coronary artery disease.

Authors:
Ron Do Cristen J Willer Ellen M Schmidt Sebanti Sengupta Chi Gao Gina M Peloso Stefan Gustafsson Stavroula Kanoni Andrea Ganna Jin Chen Martin L Buchkovich Samia Mora Jacques S Beckmann Jennifer L Bragg-Gresham Hsing-Yi Chang Ayşe Demirkan Heleen M Den Hertog Louise A Donnelly Georg B Ehret Tõnu Esko Mary F Feitosa Teresa Ferreira Krista Fischer Pierre Fontanillas Ross M Fraser Daniel F Freitag Deepti Gurdasani Kauko Heikkilä Elina Hyppönen Aaron Isaacs Anne U Jackson Asa Johansson Toby Johnson Marika Kaakinen Johannes Kettunen Marcus E Kleber Xiaohui Li Jian'an Luan Leo-Pekka Lyytikäinen Patrik K E Magnusson Massimo Mangino Evelin Mihailov May E Montasser Martina Müller-Nurasyid Ilja M Nolte Jeffrey R O'Connell Cameron D Palmer Markus Perola Ann-Kristin Petersen Serena Sanna Richa Saxena Susan K Service Sonia Shah Dmitry Shungin Carlo Sidore Ci Song Rona J Strawbridge Ida Surakka Toshiko Tanaka Tanya M Teslovich Gudmar Thorleifsson Evita G Van den Herik Benjamin F Voight Kelly A Volcik Lindsay L Waite Andrew Wong Ying Wu Weihua Zhang Devin Absher Gershim Asiki Inês Barroso Latonya F Been Jennifer L Bolton Lori L Bonnycastle Paolo Brambilla Mary S Burnett Giancarlo Cesana Maria Dimitriou Alex S F Doney Angela Döring Paul Elliott Stephen E Epstein Gudmundur Ingi Eyjolfsson Bruna Gigante Mark O Goodarzi Harald Grallert Martha L Gravito Christopher J Groves Göran Hallmans Anna-Liisa Hartikainen Caroline Hayward Dena Hernandez Andrew A Hicks Hilma Holm Yi-Jen Hung Thomas Illig Michelle R Jones Pontiano Kaleebu John J P Kastelein Kay-Tee Khaw Eric Kim Norman Klopp Pirjo Komulainen Meena Kumari Claudia Langenberg Terho Lehtimäki Shih-Yi Lin Jaana Lindström Ruth J F Loos François Mach Wendy L McArdle Christa Meisinger Braxton D Mitchell Gabrielle Müller Ramaiah Nagaraja Narisu Narisu Tuomo V M Nieminen Rebecca N Nsubuga Isleifur Olafsson Ken K Ong Aarno Palotie Theodore Papamarkou Cristina Pomilla Anneli Pouta Daniel J Rader Muredach P Reilly Paul M Ridker Fernando Rivadeneira Igor Rudan Aimo Ruokonen Nilesh Samani Hubert Scharnagl Janet Seeley Kaisa Silander Alena Stančáková Kathleen Stirrups Amy J Swift Laurence Tiret Andre G Uitterlinden L Joost van Pelt Sailaja Vedantam Nicholas Wainwright Cisca Wijmenga Sarah H Wild Gonneke Willemsen Tom Wilsgaard James F Wilson Elizabeth H Young Jing Hua Zhao Linda S Adair Dominique Arveiler Themistocles L Assimes Stefania Bandinelli Franklyn Bennett Murielle Bochud Bernhard O Boehm Dorret I Boomsma Ingrid B Borecki Stefan R Bornstein Pascal Bovet Michel Burnier Harry Campbell Aravinda Chakravarti John C Chambers Yii-Der Ida Chen Francis S Collins Richard S Cooper John Danesh George Dedoussis Ulf de Faire Alan B Feranil Jean Ferrières Luigi Ferrucci Nelson B Freimer Christian Gieger Leif C Groop Vilmundur Gudnason Ulf Gyllensten Anders Hamsten Tamara B Harris Aroon Hingorani Joel N Hirschhorn Albert Hofman G Kees Hovingh Chao Agnes Hsiung Steve E Humphries Steven C Hunt Kristian Hveem Carlos Iribarren Marjo-Riitta Järvelin Antti Jula Mika Kähönen Jaakko Kaprio Antero Kesäniemi Mika Kivimaki Jaspal S Kooner Peter J Koudstaal Ronald M Krauss Diana Kuh Johanna Kuusisto Kirsten O Kyvik Markku Laakso Timo A Lakka Lars Lind Cecilia M Lindgren Nicholas G Martin Winfried März Mark I McCarthy Colin A McKenzie Pierre Meneton Andres Metspalu Leena Moilanen Andrew D Morris Patricia B Munroe Inger Njølstad Nancy L Pedersen Chris Power Peter P Pramstaller Jackie F Price Bruce M Psaty Thomas Quertermous Rainer Rauramaa Danish Saleheen Veikko Salomaa Dharambir K Sanghera Jouko Saramies Peter E H Schwarz Wayne H-H Sheu Alan R Shuldiner Agneta Siegbahn Tim D Spector Kari Stefansson David P Strachan Bamidele O Tayo Elena Tremoli Jaakko Tuomilehto Matti Uusitupa Cornelia M van Duijn Peter Vollenweider Lars Wallentin Nicholas J Wareham John B Whitfield Bruce H R Wolffenbuttel David Altshuler Jose M Ordovas Eric Boerwinkle Colin N A Palmer Unnur Thorsteinsdottir Daniel I Chasman Jerome I Rotter Paul W Franks Samuli Ripatti L Adrienne Cupples Manjinder S Sandhu Stephen S Rich Michael Boehnke Panos Deloukas Karen L Mohlke Erik Ingelsson Goncalo R Abecasis Mark J Daly Benjamin M Neale Sekar Kathiresan

Nat Genet 2013 Nov 6;45(11):1345-52. Epub 2013 Oct 6.

1] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA. [4] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.2795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904346PMC
November 2013

Discovery and refinement of loci associated with lipid levels.

Authors:
Cristen J Willer Ellen M Schmidt Sebanti Sengupta Gina M Peloso Stefan Gustafsson Stavroula Kanoni Andrea Ganna Jin Chen Martin L Buchkovich Samia Mora Jacques S Beckmann Jennifer L Bragg-Gresham Hsing-Yi Chang Ayşe Demirkan Heleen M Den Hertog Ron Do Louise A Donnelly Georg B Ehret Tõnu Esko Mary F Feitosa Teresa Ferreira Krista Fischer Pierre Fontanillas Ross M Fraser Daniel F Freitag Deepti Gurdasani Kauko Heikkilä Elina Hyppönen Aaron Isaacs Anne U Jackson Åsa Johansson Toby Johnson Marika Kaakinen Johannes Kettunen Marcus E Kleber Xiaohui Li Jian'an Luan Leo-Pekka Lyytikäinen Patrik K E Magnusson Massimo Mangino Evelin Mihailov May E Montasser Martina Müller-Nurasyid Ilja M Nolte Jeffrey R O'Connell Cameron D Palmer Markus Perola Ann-Kristin Petersen Serena Sanna Richa Saxena Susan K Service Sonia Shah Dmitry Shungin Carlo Sidore Ci Song Rona J Strawbridge Ida Surakka Toshiko Tanaka Tanya M Teslovich Gudmar Thorleifsson Evita G Van den Herik Benjamin F Voight Kelly A Volcik Lindsay L Waite Andrew Wong Ying Wu Weihua Zhang Devin Absher Gershim Asiki Inês Barroso Latonya F Been Jennifer L Bolton Lori L Bonnycastle Paolo Brambilla Mary S Burnett Giancarlo Cesana Maria Dimitriou Alex S F Doney Angela Döring Paul Elliott Stephen E Epstein Gudmundur Ingi Eyjolfsson Bruna Gigante Mark O Goodarzi Harald Grallert Martha L Gravito Christopher J Groves Göran Hallmans Anna-Liisa Hartikainen Caroline Hayward Dena Hernandez Andrew A Hicks Hilma Holm Yi-Jen Hung Thomas Illig Michelle R Jones Pontiano Kaleebu John J P Kastelein Kay-Tee Khaw Eric Kim Norman Klopp Pirjo Komulainen Meena Kumari Claudia Langenberg Terho Lehtimäki Shih-Yi Lin Jaana Lindström Ruth J F Loos François Mach Wendy L McArdle Christa Meisinger Braxton D Mitchell Gabrielle Müller Ramaiah Nagaraja Narisu Narisu Tuomo V M Nieminen Rebecca N Nsubuga Isleifur Olafsson Ken K Ong Aarno Palotie Theodore Papamarkou Cristina Pomilla Anneli Pouta Daniel J Rader Muredach P Reilly Paul M Ridker Fernando Rivadeneira Igor Rudan Aimo Ruokonen Nilesh Samani Hubert Scharnagl Janet Seeley Kaisa Silander Alena Stančáková Kathleen Stirrups Amy J Swift Laurence Tiret Andre G Uitterlinden L Joost van Pelt Sailaja Vedantam Nicholas Wainwright Cisca Wijmenga Sarah H Wild Gonneke Willemsen Tom Wilsgaard James F Wilson Elizabeth H Young Jing Hua Zhao Linda S Adair Dominique Arveiler Themistocles L Assimes Stefania Bandinelli Franklyn Bennett Murielle Bochud Bernhard O Boehm Dorret I Boomsma Ingrid B Borecki Stefan R Bornstein Pascal Bovet Michel Burnier Harry Campbell Aravinda Chakravarti John C Chambers Yii-Der Ida Chen Francis S Collins Richard S Cooper John Danesh George Dedoussis Ulf de Faire Alan B Feranil Jean Ferrières Luigi Ferrucci Nelson B Freimer Christian Gieger Leif C Groop Vilmundur Gudnason Ulf Gyllensten Anders Hamsten Tamara B Harris Aroon Hingorani Joel N Hirschhorn Albert Hofman G Kees Hovingh Chao Agnes Hsiung Steve E Humphries Steven C Hunt Kristian Hveem Carlos Iribarren Marjo-Riitta Järvelin Antti Jula Mika Kähönen Jaakko Kaprio Antero Kesäniemi Mika Kivimaki Jaspal S Kooner Peter J Koudstaal Ronald M Krauss Diana Kuh Johanna Kuusisto Kirsten O Kyvik Markku Laakso Timo A Lakka Lars Lind Cecilia M Lindgren Nicholas G Martin Winfried März Mark I McCarthy Colin A McKenzie Pierre Meneton Andres Metspalu Leena Moilanen Andrew D Morris Patricia B Munroe Inger Njølstad Nancy L Pedersen Chris Power Peter P Pramstaller Jackie F Price Bruce M Psaty Thomas Quertermous Rainer Rauramaa Danish Saleheen Veikko Salomaa Dharambir K Sanghera Jouko Saramies Peter E H Schwarz Wayne H-H Sheu Alan R Shuldiner Agneta Siegbahn Tim D Spector Kari Stefansson David P Strachan Bamidele O Tayo Elena Tremoli Jaakko Tuomilehto Matti Uusitupa Cornelia M van Duijn Peter Vollenweider Lars Wallentin Nicholas J Wareham John B Whitfield Bruce H R Wolffenbuttel Jose M Ordovas Eric Boerwinkle Colin N A Palmer Unnur Thorsteinsdottir Daniel I Chasman Jerome I Rotter Paul W Franks Samuli Ripatti L Adrienne Cupples Manjinder S Sandhu Stephen S Rich Michael Boehnke Panos Deloukas Sekar Kathiresan Karen L Mohlke Erik Ingelsson Gonçalo R Abecasis

Nat Genet 2013 Nov 6;45(11):1274-1283. Epub 2013 Oct 6.

Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838666PMC
November 2013

HRG regulates tumor progression, epithelial to mesenchymal transition and metastasis via platelet-induced signaling in the pre-tumorigenic microenvironment.

Angiogenesis 2013 Oct 22;16(4):889-902. Epub 2013 Jun 22.

Department of Medical Biochemistry and Microbiology, Uppsala Biomedical Center, Uppsala University, Husargatan 3, 751 23, Uppsala, Sweden.

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October 2013

High-sensitive cardiac troponin T and its relations to cardiovascular risk factors, morbidity, and mortality in elderly men.

Am Heart J 2013 Sep 13;166(3):541-8. Epub 2013 Aug 13.

Department of Medical Sciences, Uppsala University, Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ahj.2013.07.004DOI Listing
September 2013

Biomarkers in atrial fibrillation: a clinical review.

Eur Heart J 2013 May 5;34(20):1475-80. Epub 2013 Feb 5.

Uppsala Clinical Research Center (UCR), Uppsala University, Uppsala Science Park, Uppsala, Sweden.

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http://dx.doi.org/10.1093/eurheartj/eht024DOI Listing
May 2013

Evaluation of microparticles in whole blood by multicolour flow cytometry assay.

Scand J Clin Lab Invest 2013 Apr 1;73(3):229-39. Epub 2013 Mar 1.

Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.3109/00365513.2013.769278DOI Listing
April 2013

Large-scale association analysis identifies new risk loci for coronary artery disease.

Authors:
Panos Deloukas Stavroula Kanoni Christina Willenborg Martin Farrall Themistocles L Assimes John R Thompson Erik Ingelsson Danish Saleheen Jeanette Erdmann Benjamin A Goldstein Kathleen Stirrups Inke R König Jean-Baptiste Cazier Asa Johansson Alistair S Hall Jong-Young Lee Cristen J Willer John C Chambers Tõnu Esko Lasse Folkersen Anuj Goel Elin Grundberg Aki S Havulinna Weang K Ho Jemma C Hopewell Niclas Eriksson Marcus E Kleber Kati Kristiansson Per Lundmark Leo-Pekka Lyytikäinen Suzanne Rafelt Dmitry Shungin Rona J Strawbridge Gudmar Thorleifsson Emmi Tikkanen Natalie Van Zuydam Benjamin F Voight Lindsay L Waite Weihua Zhang Andreas Ziegler Devin Absher David Altshuler Anthony J Balmforth Inês Barroso Peter S Braund Christof Burgdorf Simone Claudi-Boehm David Cox Maria Dimitriou Ron Do Alex S F Doney NourEddine El Mokhtari Per Eriksson Krista Fischer Pierre Fontanillas Anders Franco-Cereceda Bruna Gigante Leif Groop Stefan Gustafsson Jörg Hager Göran Hallmans Bok-Ghee Han Sarah E Hunt Hyun M Kang Thomas Illig Thorsten Kessler Joshua W Knowles Genovefa Kolovou Johanna Kuusisto Claudia Langenberg Cordelia Langford Karin Leander Marja-Liisa Lokki Anders Lundmark Mark I McCarthy Christa Meisinger Olle Melander Evelin Mihailov Seraya Maouche Andrew D Morris Martina Müller-Nurasyid Kjell Nikus John F Peden N William Rayner Asif Rasheed Silke Rosinger Diana Rubin Moritz P Rumpf Arne Schäfer Mohan Sivananthan Ci Song Alexandre F R Stewart Sian-Tsung Tan Gudmundur Thorgeirsson C Ellen van der Schoot Peter J Wagner George A Wells Philipp S Wild Tsun-Po Yang Philippe Amouyel Dominique Arveiler Hanneke Basart Michael Boehnke Eric Boerwinkle Paolo Brambilla Francois Cambien Adrienne L Cupples Ulf de Faire Abbas Dehghan Patrick Diemert Stephen E Epstein Alun Evans Marco M Ferrario Jean Ferrières Dominique Gauguier Alan S Go Alison H Goodall Villi Gudnason Stanley L Hazen Hilma Holm Carlos Iribarren Yangsoo Jang Mika Kähönen Frank Kee Hyo-Soo Kim Norman Klopp Wolfgang Koenig Wolfgang Kratzer Kari Kuulasmaa Markku Laakso Reijo Laaksonen Ji-Young Lee Lars Lind Willem H Ouwehand Sarah Parish Jeong E Park Nancy L Pedersen Annette Peters Thomas Quertermous Daniel J Rader Veikko Salomaa Eric Schadt Svati H Shah Juha Sinisalo Klaus Stark Kari Stefansson David-Alexandre Trégouët Jarmo Virtamo Lars Wallentin Nicholas Wareham Martina E Zimmermann Markku S Nieminen Christian Hengstenberg Manjinder S Sandhu Tomi Pastinen Ann-Christine Syvänen G Kees Hovingh George Dedoussis Paul W Franks Terho Lehtimäki Andres Metspalu Pierre A Zalloua Agneta Siegbahn Stefan Schreiber Samuli Ripatti Stefan S Blankenberg Markus Perola Robert Clarke Bernhard O Boehm Christopher O'Donnell Muredach P Reilly Winfried März Rory Collins Sekar Kathiresan Anders Hamsten Jaspal S Kooner Unnur Thorsteinsdottir John Danesh Colin N A Palmer Robert Roberts Hugh Watkins Heribert Schunkert Nilesh J Samani

Nat Genet 2013 Jan 2;45(1):25-33. Epub 2012 Dec 2.

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http://dx.doi.org/10.1038/ng.2480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679547PMC
January 2013