Agnes Kittel

Agnes Kittel

Agnes Kittel

Agnes Kittel

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P2X7 Receptors Drive Poly(I:C) Induced Autism-like Behavior in Mice.

J Neurosci 2019 Mar 25;39(13):2542-2561. Epub 2019 Jan 25.

Laboratory of Molecular Pharmacology, Institute of Experimental Medicine, Hungarian Academy of Sciences, 1083 Budapest, Hungary, and

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http://dx.doi.org/10.1523/JNEUROSCI.1895-18.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435822PMC
March 2019

Detection and proteomic characterization of extracellular vesicles in human pancreatic juice.

Biochem Biophys Res Commun 2018 04 21;499(1):37-43. Epub 2018 Mar 21.

Department of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; MTA-SE Immune-Proteogenomics Extracellular Vesicles Research Group, Budapest, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.03.107DOI Listing
April 2018

Extracellular vesicles regulate the human osteoclastogenesis: divergent roles in discrete inflammatory arthropathies.

Cell Mol Life Sci 2017 10 10;74(19):3599-3611. Epub 2017 May 10.

Department of Genetics, Cell- and Immunobiology, Semmelweis University, Nagyvárad tér 4, 1089, Budapest, Hungary.

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http://link.springer.com/10.1007/s00018-017-2535-8
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http://dx.doi.org/10.1007/s00018-017-2535-8DOI Listing
October 2017

P2X7 Receptors Drive Spine Synapse Plasticity in the Learned Helplessness Model of Depression.

Int J Neuropsychopharmacol 2017 10;20(10):813-822

Laboratory of Molecular Pharmacology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary; János Szentágothai School of Neurosciences, Semmelweis University School of PhD Studies, Budapest, Hungary.

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http://dx.doi.org/10.1093/ijnp/pyx046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632310PMC
October 2017

Effect of rat spinal cord injury (hemisection) on the ex vivo uptake and release of [H]noradrenaline from a slice preparation.

Brain Res Bull 2017 May 20;131:150-155. Epub 2017 Apr 20.

Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary; Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.brainresbull.2017.04.007DOI Listing
May 2017

Functionally and morphologically distinct populations of extracellular vesicles produced by human neutrophilic granulocytes.

J Leukoc Biol 2015 Oct 18;98(4):583-9. Epub 2015 May 18.

*Department of Physiology and Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary; Institute of Experimental Medicine of the Hungarian Academy of Sciences, Budapest, Hungary; and Department of Medicine, University of Louisville, Louisville, Kentucky, USA

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http://dx.doi.org/10.1189/jlb.3VMA1014-514RDOI Listing
October 2015

Differential detergent sensitivity of extracellular vesicle subpopulations.

Org Biomol Chem 2015 Oct;13(38):9775-82

Department of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1039/c5ob01451dDOI Listing
October 2015

Sucrose esters increase drug penetration, but do not inhibit p-glycoprotein in caco-2 intestinal epithelial cells.

J Pharm Sci 2014 Oct 16;103(10):3107-19. Epub 2014 Jul 16.

Institute of Biophysics, Biological Research Centre, Hungarian Academy of Sciences, Szeged, H-6726, Hungary; Department of Pharmaceutical Technology, University of Szeged, Szeged, H-6720, Hungary.

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http://dx.doi.org/10.1002/jps.24085DOI Listing
October 2014

Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles.

J Mol Cell Cardiol 2014 Mar 16;68:75-8. Epub 2014 Jan 16.

Cardiometabolic Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary; Cardiovascular Research Group, Department of Biochemistry, University of Szeged, Szeged, Hungary. Electronic address:

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http://ac.els-cdn.com/S0022282814000145/1-s2.0-S002228281400
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http://real.mtak.hu/16548/1/1-s2.0-S0022282814000145-main.pd
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http://linkinghub.elsevier.com/retrieve/pii/S002228281400014
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http://dx.doi.org/10.1016/j.yjmcc.2014.01.004DOI Listing
March 2014

Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomes.

J Extracell Vesicles 2013 12;2. Epub 2013 Sep 12.

Department of Internal Medicine and Clinical Nutrition, Krefting Research Centre, University of Gothenburg, Gothenburg, Sweden ; Department of Health Sciences, University of Eastern Piedmont, Novara, Italy.

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http://dx.doi.org/10.3402/jev.v2i0.20677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823106PMC
November 2013

Retinoic acid and hydrocortisone strengthen the barrier function of human RPMI 2650 cells, a model for nasal epithelial permeability.

Cytotechnology 2013 May 2;65(3):395-406. Epub 2012 Sep 2.

Laboratory of Molecular Neurobiology, Institute of Biophysics, Biological Research Centre of the Hungarian Academy of Sciences, Temesvári krt. 62, 6726, Szeged, Hungary.

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http://dx.doi.org/10.1007/s10616-012-9493-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597180PMC
May 2013

The recently identified hexosaminidase D enzyme substantially contributes to the elevated hexosaminidase activity in rheumatoid arthritis.

Immunol Lett 2013 Jan 23;149(1-2):71-6. Epub 2012 Oct 23.

Department of Genetics, Cell and Immunobiology, Semmelweis University, Nagyvárad tér 4, Budapest, H-1089, Hungary.

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http://dx.doi.org/10.1016/j.imlet.2012.10.012DOI Listing
January 2013

The medial habenula contains a specific nonstellate subtype of astrocyte expressing the ectonucleotidase NTPDase2.

Glia 2012 Dec 2;60(12):1860-70. Epub 2012 Aug 2.

Institute of Cell Biology and Neuroscience, Biologicum, Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.1002/glia.22402DOI Listing
December 2012

The role of purinergic signaling in depressive disorders.

Neuropsychopharmacol Hung 2012 Dec;14(4):231-8

Laboratory of Molecular Pharmacology, Institute of Experimental Medicine, Hungarian Academy of Sciences IEM HAS, H-1083 Budapest, Hungary.

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December 2012

Presynaptic α₂-adrenoceptors control the inhibitory action of presynaptic CB₁ cannabinoid receptors on prefrontocortical norepinephrine release in the rat.

Neuropharmacology 2012 Oct 18;63(5):784-97. Epub 2012 Jun 18.

Laboratory of Molecular Pharmacology, Institute of Experimental Medicine, Hungarian Academy of Sciences-IEM-HAS, H-1083 Budapest, Szigony U. 43, Hungary.

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http://dx.doi.org/10.1016/j.neuropharm.2012.06.003DOI Listing
October 2012

The effect of sucrose esters on a culture model of the nasal barrier.

Toxicol In Vitro 2012 Apr 17;26(3):445-54. Epub 2012 Jan 17.

Laboratory of Molecular Neurobiology, Institute of Biophysics, Biological Research Centre of the Hungarian Academy of Sciences, Temesvári Krt. 62, H-6726 Szeged, Hungary.

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https://linkinghub.elsevier.com/retrieve/pii/S08872333120001
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http://dx.doi.org/10.1016/j.tiv.2012.01.015DOI Listing
April 2012

Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice.

J Proteomics 2011 Sep 19;74(10):2025-33. Epub 2011 May 19.

Chemical Research Center of the Hungarian Academy of Sciences, Budapest, Pusztaszeri út 59-67, 1025, Hungary.

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http://dx.doi.org/10.1016/j.jprot.2011.05.023DOI Listing
September 2011

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles.

Cell Mol Life Sci 2011 Aug 11;68(16):2667-88. Epub 2011 May 11.

Department of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Nagyvárad tér, Hungary.

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http://dx.doi.org/10.1007/s00018-011-0689-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142546PMC
August 2011

Oxygen-glucose deprivation increases the enzymatic activity and the microvesicle-mediated release of ectonucleotidases in the cells composing the blood-brain barrier.

Neurochem Int 2011 Aug 6;59(2):259-71. Epub 2011 Jun 6.

Laboratory of Molecular and Cellular Pharmacology of Purinergic Transmission, Department of Pharmacological Sciences, Università degli Studi di Milano, Via Balzaretti, 9, 20133 Milan, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S01970186110018
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http://dx.doi.org/10.1016/j.neuint.2011.05.013DOI Listing
August 2011

Protection of the blood-brain barrier by pentosan against amyloid-β-induced toxicity.

J Alzheimers Dis 2010 ;22(3):777-94

Laboratory of Molecular Neurobiology, Institute of Biophysics, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary.

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http://www.medra.org/servlet/aliasResolver?alias=iospress&am
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http://dx.doi.org/10.3233/JAD-2010-100759DOI Listing
June 2011

Lack of neuroprotection in the absence of P2X7 receptors in toxin-induced animal models of Parkinson's disease.

Mol Neurodegener 2011 May 4;6:28. Epub 2011 May 4.

Laboratory of Molecular Pharmacology, Institute of Experimental Medicine, Hungarian Academy of Sciences, H-1083 Budapest, Szigony u, 43, Hungary.

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http://dx.doi.org/10.1186/1750-1326-6-28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113297PMC
May 2011

Increased serum concentration of immune cell derived microparticles in polymyositis/dermatomyositis.

Immunol Lett 2010 Feb 4;128(2):124-30. Epub 2010 Jan 4.

Department of Genetics, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.imlet.2009.12.018DOI Listing
February 2010

A new blood-brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes.

Neurochem Int 2009 Mar-Apr;54(3-4):253-63. Epub 2008 Dec 7.

Department of Pharmacology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Japan.

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http://dx.doi.org/10.1016/j.neuint.2008.12.002DOI Listing
July 2009

P2Y receptor mediated inhibitory modulation of noradrenaline release in response to electrical field stimulation and ischemic conditions in superfused rat hippocampus slices.

J Neurochem 2008 Jul 1;106(1):347-60. Epub 2008 Jul 1.

Laboratory of Molecular Pharmacology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary.

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http://dx.doi.org/10.1111/j.1471-4159.2008.05391.xDOI Listing
July 2008

Modulation of dopaminergic neurotransmission in rat striatum upon in vitro and in vivo diclofenac treatment.

J Neurochem 2008 Apr 25;105(2):360-8. Epub 2007 Nov 25.

Institute of Neurobiology (former Institute of Physiology), Bulgarian Academy of Sciences, Sofia, Bulgaria.

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http://doi.wiley.com/10.1111/j.1471-4159.2007.05141.x
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http://dx.doi.org/10.1111/j.1471-4159.2007.05141.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2324205PMC
April 2008

Modulation of neurotransmitter release by P2X and P2Y receptors in the rat spinal cord.

Neuropharmacology 2008 Feb 11;54(2):375-86. Epub 2007 Dec 11.

Laboratory of Molecular Pharmacology, Institute of Experimental Medicine, Hungarian Academy of Sciences, H-1450 Budapest POB 67, Hungary.

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http://dx.doi.org/10.1016/j.neuropharm.2007.10.013DOI Listing
February 2008

Transient changes in the localization and activity of ecto-nucleotidases in rat hippocampus following lipopolysaccharide treatment.

Int J Dev Neurosci 2007 Aug 17;25(5):275-82. Epub 2007 May 17.

Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.ijdevneu.2007.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239665PMC
August 2007

Endotoxin can decrease isolated rat parotid acinar cell amylase secretion in a nitric oxide-independent manner.

Eur J Pharmacol 2005 Nov 25;524(1-3):169-73. Epub 2005 Oct 25.

Department of Pediatrics and Orthodontics, Faculty of Dentistry, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.ejphar.2005.09.019DOI Listing
November 2005

Increased sensitivity of striatal dopamine release to H2O2 upon chronic rotenone treatment.

Free Radic Biol Med 2005 Jul 25;39(1):133-42. Epub 2005 Mar 25.

Department of Pharmacology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest.

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http://dx.doi.org/10.1016/j.freeradbiomed.2005.02.034DOI Listing
July 2005

Expression of NTPDase1 and caveolins in human cardiovascular disease.

Histochem Cell Biol 2005 Jul 19;124(1):51-9. Epub 2005 Jul 19.

Department of Pharmacology, Hungarian Academy of Sciences, Institute of Experimental Medicine, P.O. Box 67, 1450 Budapest, Hungary.

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http://dx.doi.org/10.1007/s00418-005-0018-8DOI Listing
July 2005

Localization of nucleoside triphosphate diphosphohydrolase-1 (NTPDase1) and NTPDase2 in pancreas and salivary gland.

J Histochem Cytochem 2004 Jul;52(7):861-71

Department of Pharmacology, Institute of Experimental Medicine, Hungarian Academy of Sciences, PO Box 67, 1450 Budapest, Hungary.

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http://dx.doi.org/10.1369/jhc.3A6167.2004DOI Listing
July 2004

ATP and ATPase secretion by exocrine pancreas in rat, guinea pig, and human.

Pancreas 2004 Jul;29(1):53-60

Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary.

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http://dx.doi.org/10.1097/00006676-200407000-00056DOI Listing
July 2004

Localization of NTPDase1/CD39 in normal and transformed human pancreas.

J Histochem Cytochem 2002 Apr;50(4):549-56

Department of Pathophysiology, Laboratory of Gastrointestinal Research, Institute of Experimental Medicine, Hungarian Academy of Sciences, PO Box 67, 1450 Budapest, Hungary.

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http://dx.doi.org/10.1177/002215540205000412DOI Listing
April 2002