Publications by authors named "Agnar Helgason"

79Publications

Humoral Immune Response to SARS-CoV-2 in Iceland.

N Engl J Med 2020 Sep 1. Epub 2020 Sep 1.

From deCODE Genetics/Amgen (D.F.G., G.L.N., P.M., K.G., H.H., A.O.A., K. Bjarnadottir, B. Thorsteinsdottir, S.K., K. Birgisdottir, A.M.K., G.A.A., E.V.I., M.A., F.J., A.B.A., J.B., B.E., R.F., E.E.G., S.G., K.R.G., A.G., A.H., B.O.J., A.J., H.J., T.K., D.N.M., O.T.M., S.R., L.R., A.S., G. Sveinbjornsson, K.E.S., E.A.T., B. Thorbjornsson, J.S., G.M., G.G., U.T., I.J., P.S., K.S.), the School of Engineering and Natural Sciences (D.F.G., P.M.), the Department of Anthropology (A.H.), the BioMedical Center (K.G.K.), and the Faculty of Medicine, School of Health Sciences (M.I.S., M.G., K.G.K., R.P., U.T., I.J., K.S.), University of Iceland, Internal Medicine and Rehabilitation Services (E.E., D.H., R.F.I., M.G., L.B.O., M.K., R.P.), the Division of Anesthesia and Intensive Care Medicine (M.I.S.), and the Department of Clinical Microbiology (O.S.G., T.R.G., K.G.K., M.S.), Landspitali-the National University Hospital, and the Directorate of Health (G. Sigmundsdottir, M.T., K.S.J., A.M., T.G.), Reykjavik, and the Health Care Institution of South Iceland, Selfoss (S.H.K.) - all in Iceland.

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http://dx.doi.org/10.1056/NEJMoa2026116DOI Listing
September 2020

Spread of SARS-CoV-2 in the Icelandic Population.

N Engl J Med 2020 06 14;382(24):2302-2315. Epub 2020 Apr 14.

From deCODE Genetics-Amgen (D.F.G., A.H., H.J., O.T.M., P.M., G.L.N., J.S., A.S., P.S., A.B.A., B.E., R.F., E.E.G., G.G., K.R.G., A.G., H.H., B.O.J., A.J., F.J., T.K., D.N.M., L.R., G. Sveinbjornsson, K.E.S., E.A.T., B.T., G.M., I.J., U.T., K.S.), the School of Engineering and Natural Sciences (D.F.G., P.M.), the Department of Anthropology (A.H.), the Faculty of Medicine, School of Health Sciences (A.L., I.J., K.G.K., U.T., K.S.), and the BioMedical Center of the University of Iceland (K.G.K.), University of Iceland, the Department of Clinical Microbiology, Landspitali-National University Hospital (O.S.G., T.R.G., M.S., A.L., K.G.K.) and the Directorate of Health (K.S.J., G. Sigmundsdottir, A.D.M., T.G.) - all in Reykjavik, Iceland.

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http://dx.doi.org/10.1056/NEJMoa2006100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175425PMC
June 2020

Associations of autozygosity with a broad range of human phenotypes.

Authors:
David W Clark Yukinori Okada Kristjan H S Moore Dan Mason Nicola Pirastu Ilaria Gandin Hannele Mattsson Catriona L K Barnes Kuang Lin Jing Hua Zhao Patrick Deelen Rebecca Rohde Claudia Schurmann Xiuqing Guo Franco Giulianini Weihua Zhang Carolina Medina-Gomez Robert Karlsson Yanchun Bao Traci M Bartz Clemens Baumbach Ginevra Biino Matthew J Bixley Marco Brumat Jin-Fang Chai Tanguy Corre Diana L Cousminer Annelot M Dekker David A Eccles Kristel R van Eijk Christian Fuchsberger He Gao Marine Germain Scott D Gordon Hugoline G de Haan Sarah E Harris Edith Hofer Alicia Huerta-Chagoya Catherine Igartua Iris E Jansen Yucheng Jia Tim Kacprowski Torgny Karlsson Marcus E Kleber Shengchao Alfred Li Ruifang Li-Gao Anubha Mahajan Koichi Matsuda Karina Meidtner Weihua Meng May E Montasser Peter J van der Most Matthias Munz Teresa Nutile Teemu Palviainen Gauri Prasad Rashmi B Prasad Tallapragada Divya Sri Priyanka Federica Rizzi Erika Salvi Bishwa R Sapkota Daniel Shriner Line Skotte Melissa C Smart Albert Vernon Smith Ashley van der Spek Cassandra N Spracklen Rona J Strawbridge Salman M Tajuddin Stella Trompet Constance Turman Niek Verweij Clara Viberti Lihua Wang Helen R Warren Robyn E Wootton Lisa R Yanek Jie Yao Noha A Yousri Wei Zhao Adebowale A Adeyemo Saima Afaq Carlos Alberto Aguilar-Salinas Masato Akiyama Matthew L Albert Matthew A Allison Maris Alver Tin Aung Fereidoun Azizi Amy R Bentley Heiner Boeing Eric Boerwinkle Judith B Borja Gert J de Borst Erwin P Bottinger Linda Broer Harry Campbell Stephen Chanock Miao-Li Chee Guanjie Chen Yii-Der I Chen Zhengming Chen Yen-Feng Chiu Massimiliano Cocca Francis S Collins Maria Pina Concas Janie Corley Giovanni Cugliari Rob M van Dam Anna Damulina Maryam S Daneshpour Felix R Day Graciela E Delgado Klodian Dhana Alexander S F Doney Marcus Dörr Ayo P Doumatey Nduna Dzimiri S Sunna Ebenesersdóttir Joshua Elliott Paul Elliott Ralf Ewert Janine F Felix Krista Fischer Barry I Freedman Giorgia Girotto Anuj Goel Martin Gögele Mark O Goodarzi Mariaelisa Graff Einat Granot-Hershkovitz Francine Grodstein Simonetta Guarrera Daniel F Gudbjartsson Kamran Guity Bjarni Gunnarsson Yu Guo Saskia P Hagenaars Christopher A Haiman Avner Halevy Tamara B Harris Mehdi Hedayati David A van Heel Makoto Hirata Imo Höfer Chao Agnes Hsiung Jinyan Huang Yi-Jen Hung M Arfan Ikram Anuradha Jagadeesan Pekka Jousilahti Yoichiro Kamatani Masahiro Kanai Nicola D Kerrison Thorsten Kessler Kay-Tee Khaw Chiea Chuen Khor Dominique P V de Kleijn Woon-Puay Koh Ivana Kolcic Peter Kraft Bernhard K Krämer Zoltán Kutalik Johanna Kuusisto Claudia Langenberg Lenore J Launer Deborah A Lawlor I-Te Lee Wen-Jane Lee Markus M Lerch Liming Li Jianjun Liu Marie Loh Stephanie J London Stephanie Loomis Yingchang Lu Jian'an Luan Reedik Mägi Ani W Manichaikul Paolo Manunta Gísli Másson Nana Matoba Xue W Mei Christa Meisinger Thomas Meitinger Massimo Mezzavilla Lili Milani Iona Y Millwood Yukihide Momozawa Amy Moore Pierre-Emmanuel Morange Hortensia Moreno-Macías Trevor A Mori Alanna C Morrison Taulant Muka Yoshinori Murakami Alison D Murray Renée de Mutsert Josyf C Mychaleckyj Mike A Nalls Matthias Nauck Matt J Neville Ilja M Nolte Ken K Ong Lorena Orozco Sandosh Padmanabhan Gunnar Pálsson James S Pankow Cristian Pattaro Alison Pattie Ozren Polasek Neil Poulter Peter P Pramstaller Lluis Quintana-Murci Katri Räikkönen Sarju Ralhan Dabeeru C Rao Wouter van Rheenen Stephen S Rich Paul M Ridker Cornelius A Rietveld Antonietta Robino Frank J A van Rooij Daniela Ruggiero Yasaman Saba Charumathi Sabanayagam Maria Sabater-Lleal Cinzia Felicita Sala Veikko Salomaa Kevin Sandow Helena Schmidt Laura J Scott William R Scott Bahareh Sedaghati-Khayat Bengt Sennblad Jessica van Setten Peter J Sever Wayne H-H Sheu Yuan Shi Smeeta Shrestha Sharvari Rahul Shukla Jon K Sigurdsson Timo Tonis Sikka Jai Rup Singh Blair H Smith Alena Stančáková Alice Stanton John M Starr Lilja Stefansdottir Leon Straker Patrick Sulem Gardar Sveinbjornsson Morris A Swertz Adele M Taylor Kent D Taylor Natalie Terzikhan Yih-Chung Tham Gudmar Thorleifsson Unnur Thorsteinsdottir Annika Tillander Russell P Tracy Teresa Tusié-Luna Ioanna Tzoulaki Simona Vaccargiu Jagadish Vangipurapu Jan H Veldink Veronique Vitart Uwe Völker Eero Vuoksimaa Salma M Wakil Melanie Waldenberger Gurpreet S Wander Ya Xing Wang Nicholas J Wareham Sarah Wild Chittaranjan S Yajnik Jian-Min Yuan Lingyao Zeng Liang Zhang Jie Zhou Najaf Amin Folkert W Asselbergs Stephan J L Bakker Diane M Becker Benjamin Lehne David A Bennett Leonard H van den Berg Sonja I Berndt Dwaipayan Bharadwaj Lawrence F Bielak Murielle Bochud Mike Boehnke Claude Bouchard Jonathan P Bradfield Jennifer A Brody Archie Campbell Shai Carmi Mark J Caulfield David Cesarini John C Chambers Giriraj Ratan Chandak Ching-Yu Cheng Marina Ciullo Marilyn Cornelis Daniele Cusi George Davey Smith Ian J Deary Rajkumar Dorajoo Cornelia M van Duijn David Ellinghaus Jeanette Erdmann Johan G Eriksson Evangelos Evangelou Michele K Evans Jessica D Faul Bjarke Feenstra Mary Feitosa Sylvain Foisy Andre Franke Yechiel Friedlander Paolo Gasparini Christian Gieger Clicerio Gonzalez Philippe Goyette Struan F A Grant Lyn R Griffiths Leif Groop Vilmundur Gudnason Ulf Gyllensten Hakon Hakonarson Anders Hamsten Pim van der Harst Chew-Kiat Heng Andrew A Hicks Hagit Hochner Heikki Huikuri Steven C Hunt Vincent W V Jaddoe Philip L De Jager Magnus Johannesson Åsa Johansson Jost B Jonas J Wouter Jukema Juhani Junttila Jaakko Kaprio Sharon L R Kardia Fredrik Karpe Meena Kumari Markku Laakso Sander W van der Laan Jari Lahti Matthias Laudes Rodney A Lea Wolfgang Lieb Thomas Lumley Nicholas G Martin Winfried März Giuseppe Matullo Mark I McCarthy Sarah E Medland Tony R Merriman Andres Metspalu Brian F Meyer Karen L Mohlke Grant W Montgomery Dennis Mook-Kanamori Patricia B Munroe Kari E North Dale R Nyholt Jeffery R O'connell Carole Ober Albertine J Oldehinkel Walter Palmas Colin Palmer Gerard G Pasterkamp Etienne Patin Craig E Pennell Louis Perusse Patricia A Peyser Mario Pirastu Tinca J C Polderman David J Porteous Danielle Posthuma Bruce M Psaty John D Rioux Fernando Rivadeneira Charles Rotimi Jerome I Rotter Igor Rudan Hester M Den Ruijter Dharambir K Sanghera Naveed Sattar Reinhold Schmidt Matthias B Schulze Heribert Schunkert Robert A Scott Alan R Shuldiner Xueling Sim Neil Small Jennifer A Smith Nona Sotoodehnia E-Shyong Tai Alexander Teumer Nicholas J Timpson Daniela Toniolo David-Alexandre Tregouet Tiinamaija Tuomi Peter Vollenweider Carol A Wang David R Weir John B Whitfield Cisca Wijmenga Tien-Yin Wong John Wright Jingyun Yang Lei Yu Babette S Zemel Alan B Zonderman Markus Perola Patrik K E Magnusson André G Uitterlinden Jaspal S Kooner Daniel I Chasman Ruth J F Loos Nora Franceschini Lude Franke Chris S Haley Caroline Hayward Robin G Walters John R B Perry Tōnu Esko Agnar Helgason Kari Stefansson Peter K Joshi Michiaki Kubo James F Wilson

Nat Commun 2019 10 31;10(1):4957. Epub 2019 Oct 31.

Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland.

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http://dx.doi.org/10.1038/s41467-019-12283-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823371PMC
October 2019

Tracking Five Millennia of Horse Management with Extensive Ancient Genome Time Series.

Authors:
Antoine Fages Kristian Hanghøj Naveed Khan Charleen Gaunitz Andaine Seguin-Orlando Michela Leonardi Christian McCrory Constantz Cristina Gamba Khaled A S Al-Rasheid Silvia Albizuri Ahmed H Alfarhan Morten Allentoft Saleh Alquraishi David Anthony Nurbol Baimukhanov James H Barrett Jamsranjav Bayarsaikhan Norbert Benecke Eloísa Bernáldez-Sánchez Luis Berrocal-Rangel Fereidoun Biglari Sanne Boessenkool Bazartseren Boldgiv Gottfried Brem Dorcas Brown Joachim Burger Eric Crubézy Linas Daugnora Hossein Davoudi Peter de Barros Damgaard María de Los Ángeles de Chorro Y de Villa-Ceballos Sabine Deschler-Erb Cleia Detry Nadine Dill Maria do Mar Oom Anna Dohr Sturla Ellingvåg Diimaajav Erdenebaatar Homa Fathi Sabine Felkel Carlos Fernández-Rodríguez Esteban García-Viñas Mietje Germonpré José D Granado Jón H Hallsson Helmut Hemmer Michael Hofreiter Aleksei Kasparov Mutalib Khasanov Roya Khazaeli Pavel Kosintsev Kristian Kristiansen Tabaldiev Kubatbek Lukas Kuderna Pavel Kuznetsov Haeedeh Laleh Jennifer A Leonard Johanna Lhuillier Corina Liesau von Lettow-Vorbeck Andrey Logvin Lembi Lõugas Arne Ludwig Cristina Luis Ana Margarida Arruda Tomas Marques-Bonet Raquel Matoso Silva Victor Merz Enkhbayar Mijiddorj Bryan K Miller Oleg Monchalov Fatemeh A Mohaseb Arturo Morales Ariadna Nieto-Espinet Heidi Nistelberger Vedat Onar Albína H Pálsdóttir Vladimir Pitulko Konstantin Pitskhelauri Mélanie Pruvost Petra Rajic Sikanjic Anita Rapan Papeša Natalia Roslyakova Alireza Sardari Eberhard Sauer Renate Schafberg Amelie Scheu Jörg Schibler Angela Schlumbaum Nathalie Serrand Aitor Serres-Armero Beth Shapiro Shiva Sheikhi Seno Irina Shevnina Sonia Shidrang John Southon Bastiaan Star Naomi Sykes Kamal Taheri William Taylor Wolf-Rüdiger Teegen Tajana Trbojević Vukičević Simon Trixl Dashzeveg Tumen Sainbileg Undrakhbold Emma Usmanova Ali Vahdati Silvia Valenzuela-Lamas Catarina Viegas Barbara Wallner Jaco Weinstock Victor Zaibert Benoit Clavel Sébastien Lepetz Marjan Mashkour Agnar Helgason Kári Stefánsson Eric Barrey Eske Willerslev Alan K Outram Pablo Librado Ludovic Orlando

Cell 2019 05 2;177(6):1419-1435.e31. Epub 2019 May 2.

Laboratoire d'Anthropobiologie Moléculaire et d'Imagerie de Synthèse, CNRS UMR 5288, Université de Toulouse, Université Paul Sabatier, 31000 Toulouse, France; Lundbeck Foundation GeoGenetics Center, University of Copenhagen, 1350K Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.03.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547883PMC
May 2019

The Y-chromosome point mutation rate in humans.

Nat Genet 2015 May 25;47(5):453-7. Epub 2015 Mar 25.

1] deCODE Genetics/Amgen, Inc., Reykjavik, Iceland. [2] Faculty of Medicine, University of Iceland, Reykjavik, Iceland.

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http://dx.doi.org/10.1038/ng.3171DOI Listing
May 2015

A direct characterization of human mutation based on microsatellites.

Nat Genet 2012 Oct 23;44(10):1161-5. Epub 2012 Aug 23.

Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.2398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459271PMC
October 2012

Single-tissue and cross-tissue heritability of gene expression via identity-by-descent in related or unrelated individuals.

PLoS Genet 2011 Feb 24;7(2):e1001317. Epub 2011 Feb 24.

Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1001317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044684PMC
February 2011

The past, present, and future of direct-to-consumer genetic tests.

Dialogues Clin Neurosci 2010 ;12(1):61-8

deCODE Genetics, Reykjavik, Iceland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181949PMC
April 2010

Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes.

Nat Genet 2007 Aug 1;39(8):977-83. Epub 2007 Jul 1.

deCODE genetics, Sturlugata 8, 101 Reykjavik, Iceland.

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http://dx.doi.org/10.1038/ng2062DOI Listing
August 2007

An Icelandic example of the impact of population structure on association studies.

Nat Genet 2005 Jan 19;37(1):90-5. Epub 2004 Dec 19.

deCODE Genetics, Sturlugata 8, 101 Reykjavík, Iceland.

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http://www.nature.com/articles/ng1492
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http://dx.doi.org/10.1038/ng1492DOI Listing
January 2005

Blondes, lost and found: representations of genes, identity, and history.

Dev World Bioeth 2003 Dec;3(2):159-69

Department of Anthropology, Oddi, University of Iceland, 101 Reykjavik, Iceland.

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http://dx.doi.org/10.1046/j.1471-8731.2003.00072.xDOI Listing
December 2003

Prion susceptibility and protective alleles exhibit marked geographic differences.

Hum Mutat 2003 Jul;22(1):104-5

Unitat de Biologia Evolutiva, Facultat de Ciències de la Salut i de la Vida, Universitat Pompeu Fabra, Barcelona, Spain.

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http://dx.doi.org/10.1002/humu.9157DOI Listing
July 2003

Y-chromosomal DNA variation in Pakistan.

Am J Hum Genet 2002 May 15;70(5):1107-24. Epub 2002 Mar 15.

Biomedical and Genetic Engineering Division, Dr. A. Q. Khan Research Laboratories, Islamabad, Pakistan.

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http://dx.doi.org/10.1086/339929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC447589PMC
May 2002