Publications by authors named "Afsoun Pourya"

8 Publications

  • Page 1 of 1

Frequency of Pathological Types of Hyperthyroidism in Thyroid Scan Patients.

Curr Med Imaging 2021 ;17(5):608-612

Department of Cardiology, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.

Background: Hyperthyroidism is a common systemic disorder where Graves' disease is known as the leading cause of the disease. Thyroid stimulating hormone, T4 and T3 antibody assay is usually performed for the diagnosis of the pathology. However, with uncertainty in the results and in order to estimate the magnitude and the exact cause of the disease, radioactive iodine uptake (RAIU) test is recommended. The aim of this study is to evaluate underlying pathology in the patients presenting hyperthyroidism using RAIU test results.

Methods: This is a cross-sectional retrospective study conducted on the patients with hyperthyroidism referred to Shahid Madani Hospital in Khorramabad. Data regarding the biochemical analysis and RAIU test was collected from the records and a questionnaire based on demographic and clinical information was completed for each patient.

Results: Of 137 patients presenting hyperthyroidism, 62.04% presented with Graves' disease, 24.08% with toxic multinodular goiter and 13.86% with toxic adenoma. 24-hour RAIU test showed that the percent of radioiodine uptake was most in toxic adenoma with 67.7%, Graves' disease 53.5% and multinodular goiter 39%, respectively. From the age-based analysis, we found that Graves' was most common in 20-30 years old individuals accounting for 34%, multinodular goiter in 50+ aged individuals with 36.3% and toxic adenoma was most prevalent in 30-40 and 50+ aged patients, with 26.3%. In our population of interest, 81.8% toxic multinodular goiter patients were females.

Conclusion: Our study presents the outcome of RAIU tests in hyperthyroidism based on the underlying pathologies. We also conclude, in light of other findings, that Graves' disease is the most common cause of hyperthyroidism in our population.
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http://dx.doi.org/10.2174/1573405616666201118142752DOI Listing
October 2021

A Descriptive Study on the Usage of Exploratory Laparotomy for Trauma Patients.

Open Access Emerg Med 2020 13;12:255-260. Epub 2020 Oct 13.

Department of Cardiology, Lorestan University of Medical Sciences, Khorramabad, Iran.

Objective: Laparotomy is commonly indicated in patients presenting blunt or penetrating trauma. This cross-sectional study is designed to evaluate the frequency and the causes of laparotomy following abdominal trauma.

Materials And Methods: The data of 71 patients who underwent laparotomy as a result of abdominal trauma in Shohada Ashayer Hospital, Khorramabad were evaluated and a questionnaire was completed for each patient. All the data were analyzed statistically using SPSS.

Results: Of 71 patients, 61 underwent positive laparotomy whereas, negative laparotomy was performed in 10 patients. The results from this study showed that the most common organ of the injury was spleen (19.7%), followed by other solid organs. The small intestine (16.4%) was found more prone to injuries in penetrating trauma. Incidence of blunt trauma injury due to road accidents was the greatest 50.82% and 20% of penetrating traumas were the result of a firearm.

Conclusion: Abdominal trauma injury is common in our study population where spleen, small intestine and other solid organs are chiefly involved. Indications of laparotomy should be fully examined in order to avoid negative laparotomies and associated complications.
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http://dx.doi.org/10.2147/OAEM.S254024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568626PMC
October 2020

Atrial Fibrillation and Ventricular Tachyarrhythmias: Advancements for Better Outcomes.

Cardiovasc Hematol Disord Drug Targets 2020 ;20(4):249-259

Department of Cardiology, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.

Cardiac arrhythmias are associated with several cardiac diseases and are prevalent in people with or without structural and valvular abnormalities. Ventricular arrhythmias (VA) can be life threating and their onset require immediate medical attention. Similarly, atrial fibrillation and flutter lead to stroke, heart failure and even death. Optimal treatment of VA is variable and depends on the medical condition associated with the rhythm disorder (which includes reversible causes such as myocardial ischemia or pro-arrhythmic drugs). While an implanted cardioverter defibrillator is often indicated in secondary prevention of VA. This review highlights the newest advancements in these techniques and management of ventricular and atrial tachyarrhythmias, along with pharmacological therapy.
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http://dx.doi.org/10.2174/1871529X20666201001143907DOI Listing
June 2021

Evaluating Mortality Rate and Associated Parameters in Patients with Acute Coronary Syndrome.

Cardiovasc Hematol Disord Drug Targets 2020 ;20(3):221-226

Student of Research Committee, Tehran University of Medical Sciences, Tehran, Iran.

Background: Acute coronary syndrome (ACS) is one of the leading causes of mortality worldwide and is characterized by unstable angina or acute myocardial infarction. The aim of this study is to evaluate the clinical characteristics of patients who died of ACS.

Methods: In this cross-sectional study, 1000 patients presenting ACS were included. Data and records of these patients were evaluated for parameters such as; deceased status, age, gender, diagnosis, ECG, common complaints, associated risk factors, Killip class, pulse, blood pressure, geographic setup (urban or rural), complications and season in which the disease was presented. Statistical analysis was performed on the data obtained using SPSS-win software.

Results: The mortality rate among ACS patients in our study was 7.1%. Of these patients, AMI was the most prevalent diagnosis and chest pain was the most common complaint. Furthermore, low blood pressure, advanced age, increased pulse rate and fall/winter season were associated with the increased risk of mortality. ST deviation was the most seen ECG finding and most of the mortalities were within the 24 hours of admission.

Conclusion: Our study reports risk factors associated with mortality in ACS patients. Advanced and timely therapeutic measurements are likely to reduce the incidence of mortality in these patients.
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http://dx.doi.org/10.2174/1871529X20666200709130533DOI Listing
May 2021

Application of tissue-engineered interventions for coronary artery bypass grafts.

Future Cardiol 2020 11 9;16(6):675-685. Epub 2020 Jul 9.

Department of Cardiology, Lorestan University of Medical Sciences, Khorramabad, Iran.

Coronary artery bypass graft is one of the extensively conducted procedures to release occlusion in the coronary vessel. Various biological grafts are used for this purpose, superiorly, saphenous vein graft, if unavailable, other vessels in the body, with likewise characteristics are exploited for the purpose. The choice of graft is yet under discovery that could impeccably meet all the requirements. Variation in perioperative and postoperative results have given uneven clinical inferences of these conduits. Alternatively, tissue-engineering is also being applied in this area for clinical improvements. This review underlines some of the commonly used grafts for coronary artery bypass graft and advancements in tissue engineering for this purpose.
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http://dx.doi.org/10.2217/fca-2019-0050DOI Listing
November 2020

Postoperative complications associated with coronary artery bypass graft surgery and their therapeutic interventions.

Future Cardiol 2020 09 4;16(5):481-496. Epub 2020 Jun 4.

Department of Cardiology, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.

Coronary artery disease is one of the commonest surgery demanding cardiovascular diseases. Coronary artery bypass graft surgery is practiced all over the world for the treatment of coronary artery disease. Systemic trauma during the surgery is associated with a wide range of complications, some of which are fatal. Preoperative risk factors such as age, previous illness and obesity are common predictors of these adverse events. Advances in therapeutic medicine have allowed timely treatment of these adverse events and co-morbidities. This review summarizes some of the most occurring complications associated with coronary artery bypass graft and corresponding treatment options.
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http://dx.doi.org/10.2217/fca-2019-0049DOI Listing
September 2020

Sigmoid volvulus after CABG surgery.

Clin Case Rep 2020 Apr 11;8(4):606-611. Epub 2020 Mar 11.

Student of Research committee Tehran University of Medical Science Tehran Iran.

We report a case of a geriatric patient who underwent CABG and developed sigmoid volvulus (SV) with recurrence. SV is a rarely reported complication of CABG. Timely diagnosis, management, and follow-up are strictly advised, particularly in geriatric patients. Immediate surgical measures are required to prevent volvulus-associated ischemia.
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http://dx.doi.org/10.1002/ccr3.2668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141711PMC
April 2020

Animal- and human-based evidence for the protective effects of stem cell therapy against cardiovascular disorders.

J Cell Physiol 2019 Feb 27. Epub 2019 Feb 27.

Department of Cardiology, Lorestan University of Medical Sciences, Khoramabad, Iran.

The increasing rate of mortality and morbidity because of cardiac diseases has called for efficient therapeutic needs. With the advancement in cell-based therapies, stem cells are abundantly studied in this area. Nearly, all sources of stem cells are experimented to treat cardiac injuries. Tissue engineering has also backed this technique by providing an advantageous platform to improve stem cell therapy. After in vitro studies, primary treatment-based research studies comprise small and large animal studies. Furthermore, these studies are implemented in human models in the form of clinical trials. Purpose of this review is to highlight the animal- and human-based studies, exploiting various stem cell sources, to treat cardiovascular disorders.
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http://dx.doi.org/10.1002/jcp.28330DOI Listing
February 2019
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