Afshan N Malik

Afshan N Malik

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Afshan N Malik

Afshan N Malik

Publications by authors named "Afshan N Malik"

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18Publications

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Regional mitochondrial DNA and cell-type changes in post-mortem brains of non-diabetic Alzheimer's disease are not present in diabetic Alzheimer's disease.

Sci Rep 2019 Aug 6;9(1):11386. Epub 2019 Aug 6.

Department of Diabetes, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.

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http://dx.doi.org/10.1038/s41598-019-47783-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684616PMC
August 2019

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.

Authors:
Aldi T Kraja Chunyu Liu Jessica L Fetterman Mariaelisa Graff Christian Theil Have Charles Gu Lisa R Yanek Mary F Feitosa Dan E Arking Daniel I Chasman Kristin Young Symen Ligthart W David Hill Stefan Weiss Jian'an Luan Franco Giulianini Ruifang Li-Gao Fernando P Hartwig Shiow J Lin Lihua Wang Tom G Richardson Jie Yao Eliana P Fernandez Mohsen Ghanbari Mary K Wojczynski Wen-Jane Lee Maria Argos Sebastian M Armasu Ruteja A Barve Kathleen A Ryan Ping An Thomas J Baranski Suzette J Bielinski Donald W Bowden Ulrich Broeckel Kaare Christensen Audrey Y Chu Janie Corley Simon R Cox Andre G Uitterlinden Fernando Rivadeneira Cheryl D Cropp E Warwick Daw Diana van Heemst Lisa de Las Fuentes He Gao Ioanna Tzoulaki Tarunveer S Ahluwalia Renée de Mutsert Leslie S Emery A Mesut Erzurumluoglu James A Perry Mao Fu Nita G Forouhi Zhenglong Gu Yang Hai Sarah E Harris Gibran Hemani Steven C Hunt Marguerite R Irvin Anna E Jonsson Anne E Justice Nicola D Kerrison Nicholas B Larson Keng-Hung Lin Latisha D Love-Gregory Rasika A Mathias Joseph H Lee Matthias Nauck Raymond Noordam Ken K Ong James Pankow Amit Patki Alison Pattie Astrid Petersmann Qibin Qi Rasmus Ribel-Madsen Rebecca Rohde Kevin Sandow Theresia M Schnurr Tamar Sofer John M Starr Adele M Taylor Alexander Teumer Nicholas J Timpson Hugoline G de Haan Yujie Wang Peter E Weeke Christine Williams Hongsheng Wu Wei Yang Donglin Zeng Daniel R Witte Bruce S Weir Nicholas J Wareham Henrik Vestergaard Stephen T Turner Christian Torp-Pedersen Evie Stergiakouli Wayne Huey-Herng Sheu Frits R Rosendaal M Arfan Ikram Oscar H Franco Paul M Ridker Thomas T Perls Oluf Pedersen Ellen A Nohr Anne B Newman Allan Linneberg Claudia Langenberg Tuomas O Kilpeläinen Sharon L R Kardia Marit E Jørgensen Torben Jørgensen Thorkild I A Sørensen Georg Homuth Torben Hansen Mark O Goodarzi Ian J Deary Cramer Christensen Yii-Der Ida Chen Aravinda Chakravarti Ivan Brandslund Klaus Bonnelykke Kent D Taylor James G Wilson Santiago Rodriguez Gail Davies Bernardo L Horta Bharat Thyagarajan D C Rao Niels Grarup Victor G Davila-Roman Gavin Hudson Xiuqing Guo Donna K Arnett Caroline Hayward Dhananjay Vaidya Dennis O Mook-Kanamori Hemant K Tiwari Daniel Levy Ruth J F Loos Abbas Dehghan Paul Elliott Afshan N Malik Robert A Scott Diane M Becker Mariza de Andrade Michael A Province James B Meigs Jerome I Rotter Kari E North

Am J Hum Genet 2019 01 27;104(1):112-138. Epub 2018 Dec 27.

Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27516, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323610PMC
January 2019

Hyperglycemia induced damage to mitochondrial respiration in renal mesangial and tubular cells: Implications for diabetic nephropathy.

Redox Biol 2016 12 17;10:100-107. Epub 2016 Sep 17.

Diabetes Research Group, Division of Diabetes and Nutritional Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2016.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053113PMC
December 2016

Accurate quantification of mouse mitochondrial DNA without co-amplification of nuclear mitochondrial insertion sequences.

Mitochondrion 2016 Jul 12;29:59-64. Epub 2016 May 12.

Diabetes Research Group, Division of Diabetes and Nutritional Sciences, School of Life Science and Medicine, King's College London, SE1 1UL, UK.

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http://dx.doi.org/10.1016/j.mito.2016.05.003DOI Listing
July 2016

Altered circulating mitochondrial DNA and increased inflammation in patients with diabetic retinopathy.

Diabetes Res Clin Pract 2015 Dec 22;110(3):257-65. Epub 2015 Oct 22.

King's College London, Laser and Retinal Research Unit, Department of Ophthalmology, UK; King's College London, NIHR Moorfields Biomedical Research Centre, UK.

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http://dx.doi.org/10.1016/j.diabres.2015.10.006DOI Listing
December 2015

Altered Mitochondrial Function, Mitochondrial DNA and Reduced Metabolic Flexibility in Patients With Diabetic Nephropathy.

EBioMedicine 2015 Jun 11;2(6):499-512. Epub 2015 Apr 11.

Diabetes Research Group, Division of Diabetes and Nutritional Science, Faculty of Life Sciences and Medicine, King's College London, SE1 1UL, UK.

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http://dx.doi.org/10.1016/j.ebiom.2015.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534759PMC
June 2015

Is mitochondrial DNA content a potential biomarker of mitochondrial dysfunction?

Mitochondrion 2013 Sep 22;13(5):481-92. Epub 2012 Oct 22.

Diabetes Research Group, Division of Diabetes and Nutritional Sciences, School of Medicine, King's college London, London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S15677249120023
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http://dx.doi.org/10.1016/j.mito.2012.10.011DOI Listing
September 2013

Nop-7-associated 2 (NSA2), a candidate gene for diabetic nephropathy, is involved in the TGFβ1 pathway.

Int J Biochem Cell Biol 2013 Mar 7;45(3):626-35. Epub 2012 Dec 7.

Diabetes Research Group, Division of Diabetes and Nutritional Sciences, School of Medicine, King's College London, Hodgkin Building, London Bridge, London SE1 1UL, United Kingdom.

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http://dx.doi.org/10.1016/j.biocel.2012.11.020DOI Listing
March 2013

Mitochondrial DNA as a non-invasive biomarker: accurate quantification using real time quantitative PCR without co-amplification of pseudogenes and dilution bias.

Biochem Biophys Res Commun 2011 Aug 15;412(1):1-7. Epub 2011 Jun 15.

King's College London, Diabetes Research Group, Division of Diabetes and Nutritional Sciences, School of Medicine, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X1101040
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http://dx.doi.org/10.1016/j.bbrc.2011.06.067DOI Listing
August 2011

Hyperglycemia induces elevated expression of thyroid hormone binding protein in vivo in kidney and heart and in vitro in mesangial cells.

Biochem Biophys Res Commun 2010 Jan 17;391(4):1585-91. Epub 2009 Dec 17.

Diabetes Research Group, Division of Reproduction and Endocrinology, King's College London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X090243
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http://dx.doi.org/10.1016/j.bbrc.2009.12.061DOI Listing
January 2010

Increased peripheral blood mitochondrial DNA in type 2 diabetic patients with nephropathy.

Diabetes Res Clin Pract 2009 Nov 5;86(2):e22-4. Epub 2009 Aug 5.

Diabetes Research Group, Division of Reproduction and Endocrinology, King's College London, London Bridge, London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S01688227090030
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http://dx.doi.org/10.1016/j.diabres.2009.07.002DOI Listing
November 2009

Glucose regulation of CDK7, a putative thiol related gene, in experimental diabetic nephropathy.

Biochem Biophys Res Commun 2007 May 30;357(1):237-44. Epub 2007 Mar 30.

Division of Reproduction and Endocrinology, School of Biomedical and Health Sciences, King's College London, UK.

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http://dx.doi.org/10.1016/j.bbrc.2007.03.132DOI Listing
May 2007

Glucose regulation of beta-defensin-1 mRNA in human renal cells.

Biochem Biophys Res Commun 2007 Feb 14;353(2):318-23. Epub 2006 Dec 14.

Department of Biochemistry, School of Biomedical and Health Sciences, Kings College London, Franklin-Wilkins Buildings, 150 Stamford St., London SE1 9NH, UK.

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http://dx.doi.org/10.1016/j.bbrc.2006.12.037DOI Listing
February 2007

Elevated levels of beta defensin-1 mRNA in diabetic kidneys of GK rats.

Biochem Biophys Res Commun 2003 Oct;310(2):513-21

Molecular Genetics Section, School of Life Sciences, Kings College London, 150 Stamford St., London SE1 9NN, UK.

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http://dx.doi.org/10.1016/j.bbrc.2003.09.034DOI Listing
October 2003