Publications by authors named "Afina W Lemstra"

61Publications

Pathologically Decreased CSF Levels of Synaptic Marker NPTX2 in DLB Are Correlated with Levels of Alpha-Synuclein and VGF.

Cells 2020 Dec 29;10(1). Epub 2020 Dec 29.

Neurochemistry Department, Clinical Chemistry, Amsterdam UMC, 1081 HV Amsterdam, The Netherlands.

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December 2020

β-Amyloid and tau biomarkers and clinical phenotype in dementia with Lewy bodies.

Neurology 2020 12 28;95(24):e3257-e3268. Epub 2020 Sep 28.

From the Division of Clinical Geriatrics (D.F., S.G.-P., E.W.), Center for Alzheimer's Research, Department of Neurobiology, Care Sciences, and Society, Karolinska Institutet, Stockholm, Sweden; Departments of Radiology (D.F., Z.N., C.G.S., M.L.S., V.J.L., C.R.J., K.K.), Health Sciences (S.A.P., T.G.L.), Neurology (J.G.-R., D.S.K., R.S., R.C.P., B.F.B.), Information Technology (M.L.S.), and Psychiatry and Psychology (J.A.F.), Mayo Clinic, Rochester, MN; Department of Neurology and Alzheimer Center (A.W.L.), VU University Medical Center, Amsterdam, the Netherlands; Clinical Memory Research Unit (E.L.), Department of Clinical Sciences, Lund University, Malmö, Sweden; Day Hospital of Geriatrics (F.B.), Memory Resource and Research Centre (CM2R) of Strasbourg; Department of Geriatrics (F.B.), Hopitaux Universitaires de Strasbourg; University of Strasbourg and French National Centre for Scientific Research (CNRS) (F.B.), ICube Laboratory and Federation de Medecine Translationnelle de Strasbourg (FMTS), Team Imagerie Multimodale Integrative en Sante (IMIS)/ICONE, Strasbourg, France; Department of Neurology (Z.N., J.H.), Charles University, 2nd Faculty of Medicine, Motol University Hospital, Prague, Czech Republic; Departments of Psychiatry and Psychology (T.J.F.) and Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Paracelsus-Elena-Klinik (B.M.), Kassel; and University Medical Center (B.M.), Department of Neurosurgery and Institute of Neuropathology, Göttingen, Germany; Fundació ACE (C.A.), Alzheimer Research Center and Memory Clinic, Institut Català de Neurociències Aplicades, Barcelona, Spain; International Clinical Research Center (J.H.), St. Anne's University Hospital Brno, Czech Republic; Department of Neuroscience Imaging and Clinical Sciences and CESI (L.B.), University G d'Annunzio of Chieti-Pescara, Chieti, Italy; Centre for Age-Related Medicine (K.O., D.A.), Stavanger University Hospital; Stavanger Medical Imaging Laboratory (SMIL) (K.O.), Department of Radiology, Stavanger University Hospital; Department of Electrical Engineering and Computer Science (K.O.), University of Stavanger, Norway; Department of Neurology (M.G.K.), University Medical Centre Ljubljana, Medical Faculty, University of Ljubljana, Slovenia; Institute of Psychiatry, Psychology and Neuroscience (D.A.) and Department of Neuroimaging (E.W.), Centre for Neuroimaging Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.

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December 2020

Contactin-1 Is Reduced in Cerebrospinal Fluid of Parkinson's Disease Patients and Is Present within Lewy Bodies.

Biomolecules 2020 08 12;10(8). Epub 2020 Aug 12.

Neurochemistry Laboratory, Clinical Chemistry Department, Amsterdam Neuroscience, Amsterdam University Medical Centers, Vrije Universiteit, 1105 AZ Amsterdam, The Netherlands.

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August 2020

Prodromal Dementia With Lewy Bodies: Clinical Characterization and Predictors of Progression.

Mov Disord 2020 05 11;35(5):859-867. Epub 2020 Feb 11.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam University Medical Centers, Amsterdam, the Netherlands.

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May 2020

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

Authors:
Sven J van der Lee Olivia J Conway Iris Jansen Minerva M Carrasquillo Luca Kleineidam Erik van den Akker Isabel Hernández Kristel R van Eijk Najada Stringa Jason A Chen Anna Zettergren Till F M Andlauer Monica Diez-Fairen Javier Simon-Sanchez Alberto Lleó Henrik Zetterberg Marianne Nygaard Cornelis Blauwendraat Jeanne E Savage Jonas Mengel-From Sonia Moreno-Grau Michael Wagner Juan Fortea Michael J Keogh Kaj Blennow Ingmar Skoog Manuel A Friese Olga Pletnikova Miren Zulaica Carmen Lage Itziar de Rojas Steffi Riedel-Heller Ignacio Illán-Gala Wei Wei Bernard Jeune Adelina Orellana Florian Then Bergh Xue Wang Marc Hulsman Nina Beker Niccolo Tesi Christopher M Morris Begoña Indakoetxea Lyduine E Collij Martin Scherer Estrella Morenas-Rodríguez James W Ironside Bart N M van Berckel Daniel Alcolea Heinz Wiendl Samantha L Strickland Pau Pastor Eloy Rodríguez Rodríguez Bradley F Boeve Ronald C Petersen Tanis J Ferman Jay A van Gerpen Marcel J T Reinders Ryan J Uitti Lluís Tárraga Wolfgang Maier Oriol Dols-Icardo Amit Kawalia Maria Carolina Dalmasso Mercè Boada Uwe K Zettl Natasja M van Schoor Marian Beekman Mariet Allen Eliezer Masliah Adolfo López de Munain Alexander Pantelyat Zbigniew K Wszolek Owen A Ross Dennis W Dickson Neill R Graff-Radford David Knopman Rosa Rademakers Afina W Lemstra Yolande A L Pijnenburg Philip Scheltens Thomas Gasser Patrick F Chinnery Bernhard Hemmer Martijn A Huisman Juan Troncoso Fermin Moreno Ellen A Nohr Thorkild I A Sørensen Peter Heutink Pascual Sánchez-Juan Danielle Posthuma Jordi Clarimón Kaare Christensen Nilüfer Ertekin-Taner Sonja W Scholz Alfredo Ramirez Agustín Ruiz Eline Slagboom Wiesje M van der Flier Henne Holstege

Acta Neuropathol 2020 05;139(5):959-962

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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May 2020

Parkinsonism and Bipolar Disorder.

Bipolar Disord 2020 06 30;22(4):413-415. Epub 2020 Jan 30.

Neurology, Alzheimercenter, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.

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June 2020

Amyloid-β peptides in cerebrospinal fluid of patients with dementia with Lewy bodies.

Alzheimers Res Ther 2019 10 10;11(1):83. Epub 2019 Oct 10.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, De Boelelaan 1118, 1081 HV, Amsterdam, The Netherlands.

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October 2019

VGF Peptides in Cerebrospinal Fluid of Patients with Dementia with Lewy Bodies.

Int J Mol Sci 2019 Sep 20;20(19). Epub 2019 Sep 20.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, 1081 HV Amsterdam, The Netherlands.

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September 2019

Orthostatic Hypotension: An Important Risk Factor for Clinical Progression to Mild Cognitive Impairment or Dementia. The Amsterdam Dementia Cohort.

J Alzheimers Dis 2019 ;71(1):317-325

Department of Internal Medicine and Geriatrics, Amsterdam UMC, location VUmc, Amsterdam Cardiovascular Sciences, Amsterdam, the Netherlands.

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October 2020

CSF tau proteins correlate with an atypical clinical presentation in dementia with Lewy bodies.

J Neurol Neurosurg Psychiatry 2020 01 31;91(1):109-110. Epub 2019 Jul 31.

Department of Neuroscience, Imaging and Clinical Sciences, University Chieti-Pescara, Institute of Neurology, Chieti, Italy

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January 2020

Trajectories and Determinants of Quality of Life in Dementia with Lewy Bodies and Alzheimer's Disease.

J Alzheimers Dis 2019 ;70(2):389-397

Department of Neurology, Alzheimer Center Amsterdam, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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October 2020

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

Authors:
Sven J van der Lee Olivia J Conway Iris Jansen Minerva M Carrasquillo Luca Kleineidam Erik van den Akker Isabel Hernández Kristel R van Eijk Najada Stringa Jason A Chen Anna Zettergren Till F M Andlauer Monica Diez-Fairen Javier Simon-Sanchez Alberto Lleó Henrik Zetterberg Marianne Nygaard Cornelis Blauwendraat Jeanne E Savage Jonas Mengel-From Sonia Moreno-Grau Michael Wagner Juan Fortea Michael J Keogh Kaj Blennow Ingmar Skoog Manuel A Friese Olga Pletnikova Miren Zulaica Carmen Lage Itziar de Rojas Steffi Riedel-Heller Ignacio Illán-Gala Wei Wei Bernard Jeune Adelina Orellana Florian Then Bergh Xue Wang Marc Hulsman Nina Beker Niccolo Tesi Christopher M Morris Begoña Indakoetxea Lyduine E Collij Martin Scherer Estrella Morenas-Rodríguez James W Ironside Bart N M van Berckel Daniel Alcolea Heinz Wiendl Samantha L Strickland Pau Pastor Eloy Rodríguez Rodríguez Bradley F Boeve Ronald C Petersen Tanis J Ferman Jay A van Gerpen Marcel J T Reinders Ryan J Uitti Lluís Tárraga Wolfgang Maier Oriol Dols-Icardo Amit Kawalia Maria Carolina Dalmasso Mercè Boada Uwe K Zettl Natasja M van Schoor Marian Beekman Mariet Allen Eliezer Masliah Adolfo López de Munain Alexander Pantelyat Zbigniew K Wszolek Owen A Ross Dennis W Dickson Neill R Graff-Radford David Knopman Rosa Rademakers Afina W Lemstra Yolande A L Pijnenburg Philip Scheltens Thomas Gasser Patrick F Chinnery Bernhard Hemmer Martijn A Huisman Juan Troncoso Fermin Moreno Ellen A Nohr Thorkild I A Sørensen Peter Heutink Pascual Sánchez-Juan Danielle Posthuma Jordi Clarimón Kaare Christensen Nilüfer Ertekin-Taner Sonja W Scholz Alfredo Ramirez Agustín Ruiz Eline Slagboom Wiesje M van der Flier Henne Holstege

Acta Neuropathol 2019 08 27;138(2):237-250. Epub 2019 May 27.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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August 2019

Striatal DAT and extrastriatal SERT binding in early-stage Parkinson's disease and dementia with Lewy bodies, compared with healthy controls: An I-FP-CIT SPECT study.

Neuroimage Clin 2019 12;22:101755. Epub 2019 Mar 12.

Amsterdam UMC, Vrije Universiteit Amsterdam, Psychiatry, Amsterdam Neuroscience, De Boelelaan 1117, Amsterdam, Netherlands; Amsterdam UMC, Vrije Universiteit Amsterdam, Anatomy and Neurosciences, Amsterdam Neuroscience, De Boelelaan 1117, Amsterdam, Netherlands.

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January 2020

α-Synuclein species as potential cerebrospinal fluid biomarkers for dementia with lewy bodies.

Mov Disord 2018 11 15;33(11):1724-1733. Epub 2018 Nov 15.

Neurological Disorders Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation, Doha, Qatar.

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November 2018

A signature pattern of cortical atrophy in dementia with Lewy bodies: A study on 333 patients from the European DLB consortium.

Alzheimers Dement 2019 03 12;15(3):400-409. Epub 2018 Nov 12.

Centre for Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. Electronic address:

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March 2019

Survival in memory clinic cohort is short, even in young-onset dementia.

J Neurol Neurosurg Psychiatry 2019 06 25;90(6):726-728. Epub 2018 Jul 25.

Alzheimer Center, Department of Neurology, VU University Medical Centre, Amsterdam Neuroscience, Amsterdam, The Netherlands.

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June 2019

Lower I-FP-CIT binding to the striatal dopamine transporter, but not to the extrastriatal serotonin transporter, in Parkinson's disease compared with dementia with Lewy bodies.

Neuroimage Clin 2018 6;19:130-136. Epub 2018 Apr 6.

Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands; Amsterdam Neuroscience, Amsterdam, The Netherlands.

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January 2019

Understanding hallucinations in probable Alzheimer's disease: Very low prevalence rates in a tertiary memory clinic.

Alzheimers Dement (Amst) 2018 21;10:358-362. Epub 2018 Apr 21.

Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.

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April 2018

EEG-based neurophysiological indicators of hallucinations in Alzheimer's disease: Comparison with dementia with Lewy bodies.

Neurobiol Aging 2018 07 19;67:75-83. Epub 2018 Mar 19.

Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands; Department of Neuroscience and Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Department of Biological and Medical Psychology, Faculty of Psychology, University of Bergen, Bergen, Norway.

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July 2018

Disease-related determinants are associated with mortality in dementia due to Alzheimer's disease.

Alzheimers Res Ther 2018 02 20;10(1):23. Epub 2018 Feb 20.

Alzheimer Center, Department of Neurology, VU University Medical Center, Amsterdam Neuroscience, P.O. Box 7057, 1007, MB, Amsterdam, The Netherlands.

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February 2018

An update on the genetics of dementia with Lewy bodies.

Parkinsonism Relat Disord 2017 Oct 13;43:1-8. Epub 2017 Jul 13.

Department of Neurology and Alzheimercenter Zuidwest Nederland, Erasmus Medical Center, Rotterdam, The Netherlands.

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October 2017

Random forest to differentiate dementia with Lewy bodies from Alzheimer's disease.

Alzheimers Dement (Amst) 2016 19;4:99-106. Epub 2016 Aug 19.

Department of Clinical Neurophysiology and MEG Center, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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August 2016

Distribution and Load of Amyloid-β Pathology in Parkinson Disease and Dementia with Lewy Bodies.

J Neuropathol Exp Neurol 2016 Oct 11;75(10):936-945. Epub 2016 Aug 11.

From the Department of Anatomy and Neurosciences, Section Quantitative Morphology (DHH, DLEV, EH, WDJVDB), Department of Neurology, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, The Netherlands (DHH, AWL, EMJF), Netherlands Institute for Neuroscience, Amsterdam, The Netherlands (NBB) and Department of Pathology, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, The Netherlands (AJR).

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October 2016

Dementia and Rapid Mortality: Who is at Risk?

J Alzheimers Dis 2016 04;53(1):135-42

Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.

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April 2016

Loss of EEG Network Efficiency Is Related to Cognitive Impairment in Dementia With Lewy Bodies.

Mov Disord 2015 Nov 16;30(13):1785-93. Epub 2015 Jul 16.

Alzheimer Center and Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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November 2015

Diagnostic impact of CSF biomarkers for Alzheimer's disease in a tertiary memory clinic.

Alzheimers Dement 2015 May 22;11(5):523-32. Epub 2014 Aug 22.

Alzheimer Center & Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands; Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.

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May 2015

Distinct perfusion patterns in Alzheimer's disease, frontotemporal dementia and dementia with Lewy bodies.

Eur Radiol 2014 Sep 5;24(9):2326-33. Epub 2014 Jul 5.

Department of Radiology and Nuclear Medicine, VU University Medical Center and Neuroscience Campus Amsterdam, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands,

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September 2014

EEG abnormalities are associated with different cognitive profiles in Alzheimer's disease.

Dement Geriatr Cogn Disord 2011 27;31(1):1-6. Epub 2010 Nov 27.

Alzheimer Center, Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands.

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May 2011

Pre-operative inflammatory markers and the risk of postoperative delirium in elderly patients.

Int J Geriatr Psychiatry 2008 Sep;23(9):943-8

Department of Neurology, Academic Medical Centre, Amsterdam, The Netherlands.

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September 2008

Identification of responders to rivastigmine: a prospective cohort study.

Dement Geriatr Cogn Disord 2008 23;25(1):60-6. Epub 2007 Nov 23.

Department of Neurology, Academic Medical Centre, Amsterdam, The Netherlands.

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February 2008

Cholinesterase inhibitors in dementia: yes, no, or maybe?

Age Ageing 2007 Nov 19;36(6):625-7. Epub 2007 Sep 19.

Academic Medical Centre, Department of Neurology, PO Box 22660, 1100 DD Amsterdam, The Netherlands.

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November 2007

Microglia activation in sepsis: a case-control study.

J Neuroinflammation 2007 Jan 15;4. Epub 2007 Jan 15.

Department of Neurology, Academic Medical Centre, Amsterdam, The Netherlands.

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January 2007

The cholinergic deficiency syndrome and its therapeutic implications.

Gerontology 2003 Jan-Feb;49(1):55-60

Department of Neurology, Academic Medical Center, Amsterdam, The Netherlands.

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April 2003