Publications by authors named "Afaf R Genady"

16 Publications

  • Page 1 of 1

Correction: A 99mTc-Labelled Tetrazine for Bioorthogonal Chemistry. Synthesis and Biodistribution Studies with Small Molecule trans-Cyclooctene Derivatives.

Authors:
Alyssa Vito Hussain Alarabi Shannon Czorny Omid Beiraghi Jeff Kent Nancy Janzen Afaf R Genady Salma A Al-Karmi Stephanie Rathmann Zoya Naperstkow Megan Blacker Lisset Llano Paul J Berti John F Valliant

PLoS One 2017;12(2):e0171909. Epub 2017 Feb 6.

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February 2017

A 99mTc-Labelled Tetrazine for Bioorthogonal Chemistry. Synthesis and Biodistribution Studies with Small Molecule trans-Cyclooctene Derivatives.

Authors:
Alyssa Vito Hussain Alarabi Shannon Czorny Omid Beiraghi Jeff Kent Nancy Janzen Afaf R Genady Salma A Al-Karmi Stephanie Rathmann Zoya Naperstkow Megan Blacker Lisset Llano Paul J Berti John F Valliant

PLoS One 2016 9;11(12):e0167425. Epub 2016 Dec 9.

Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario, Canada.

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July 2017

A Bone-Seeking trans-Cyclooctene for Pretargeting and Bioorthogonal Chemistry: A Proof of Concept Study Using Tc- and Lu-Labeled Tetrazines.

Authors:
Abdolreza Yazdani Holly Bilton Alyssa Vito Afaf R Genady Stephanie M Rathmann Zainab Ahmad Nancy Janzen Shannon Czorny Brian M Zeglis Lynn C Francesconi John F Valliant

J Med Chem 2016 Oct 5;59(20):9381-9389. Epub 2016 Oct 5.

Department of Chemistry and Chemical Biology, McMaster University , 1280 Main Street West, Hamilton, Ontario L8S 4M1, Canada.

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October 2016

Automated synthesis of [(18)F]DCFPyL via direct radiofluorination and validation in preclinical prostate cancer models.

Authors:
Vincent Bouvet Melinda Wuest Hans-Soenke Jans Nancy Janzen Afaf R Genady John F Valliant Francois Benard Frank Wuest

EJNMMI Res 2016 Dec 4;6(1):40. Epub 2016 May 4.

Department of Oncology, University of Alberta, 11560 University Avenue, Edmonton, AB, T6G 1Z2, Canada.

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December 2016

Preparation and Evaluation of Radiolabeled Antibody Recruiting Small Molecules That Target Prostate-Specific Membrane Antigen for Combined Radiotherapy and Immunotherapy.

Authors:
Afaf R Genady Nancy Janzen Laura Banevicius Mahmoud El-Gamal Mohamed E El-Zaria John F Valliant

J Med Chem 2016 Mar 3;59(6):2660-73. Epub 2016 Mar 3.

Department of Chemistry and Chemical Biology, McMaster University , 1280 Main Street West, Hamilton, Ontario L8S 4M1, Canada.

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March 2016

Fluorous Analogue of Chloramine-T: Preparation, X-ray Structure Determination, and Use as an Oxidant for Radioiodination and s-Tetrazine Synthesis.

Authors:
James P K Dzandzi Denis R Beckford Vera Afaf R Genady Silvia A Albu Louise J Eltringham-Smith Alfredo Capretta William P Sheffield John F Valliant

J Org Chem 2015 Jul 24;80(14):7117-25. Epub 2015 Jun 24.

§Department of Chemistry, Faculty of Science, Tanta University, Tanta, 31527 Egypt.

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July 2015

New functionalized mercaptoundecahydrododecaborate derivatives for potential application in boron neutron capture therapy: synthesis, characterization and dynamic visualization in cells.

Authors:
Afaf R Genady Joseph A Ioppolo Mohamed M Azaam Mohamed E El-Zaria

Eur J Med Chem 2015 Mar 20;93:574-83. Epub 2015 Feb 20.

Department of Chemistry, Faculty of Science, University of Tanta, 31527 Tanta, Egypt.

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March 2015

High yielding synthesis of carboranes under mild reaction conditions using a homogeneous silver(I) catalyst: direct evidence of a bimetallic intermediate.

Authors:
Mohamed E El-Zaria Kunal Keskar Afaf R Genady Joseph A Ioppolo James McNulty John F Valliant

Angew Chem Int Ed Engl 2014 May 2;53(20):5156-60. Epub 2014 Apr 2.

Department of Chemistry and Chemical Biology, McMaster University, 1280 Main St W., Hamilton, Ont., L8S 4M1 Canada; Department of Chemistry, Faculty of Science, Tanta University, 31527 Tanta (Egypt).

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May 2014

Preparation and evaluation of carborane-derived inhibitors of prostate specific membrane antigen (PSMA).

Authors:
Mohamed E El-Zaria Afaf R Genady Nancy Janzen Christina I Petlura Denis R Beckford Vera John F Valliant

Dalton Trans 2014 Apr;43(13):4950-61

Department of Chemistry and Chemical Biology, McMaster University, 1280 Main St. West, Hamilton, Ont., CanadaL8S 4M1.

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April 2014

High yielding preparation of dicarba-closo-dodecaboranes using a silver(I) mediated dehydrogenative alkyne-insertion reaction.

Authors:
Antonio Toppino Afaf R Genady Mohamed E El-Zaria James Reeve Fargol Mostofian Jeff Kent John F Valliant

Inorg Chem 2013 Aug 5;52(15):8743-9. Epub 2013 Jul 5.

Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario L8S 4M1, Canada.

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August 2013

Labeled Undecahydro-closo-dodecaborates Based on Azo Dyes for Boron Neutron Capture Therapy: Synthesis, Characterization, and Visualization in Cells.

Authors:
Afaf R Genady

Acta Chim Slov 2012 Mar;59(1):89-101

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March 2012

Amphiphilic allylation of arylidene-1,3-oxazol-5(4H)-one using bis-π-allylpalladium complexes: an approach to synthesis of cyclohexyl and cyclohexenyl α-amino acids.

Authors:
Afaf R Genady Hiroyuki Nakamura

Org Biomol Chem 2011 Oct 22;9(20):7180-9. Epub 2011 Aug 22.

Department of Chemistry, Faculty of Science, University of Tanta, 31527-Tanta, Egypt.

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October 2011

Undecahydro-closo-dodecaborates as good leaving groups in organic synthesis: generation of substituted styrenes via elimination of arylethyl dodecaborates.

Authors:
Afaf R Genady Hiroyuki Nakamura

Org Biomol Chem 2010 Oct 13;8(19):4427-35. Epub 2010 Aug 13.

Department of Chemistry, Faculty of Science, Gakushuin University, 1-5-1 Mejiro, Toshima-ku, Tokyo 171-8588, Japan.

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October 2010

Promising carboranylquinazolines for boron neutron capture therapy: synthesis, characterization, and in vitro toxicity evaluation.

Authors:
Afaf R Genady

Eur J Med Chem 2009 Jan 10;44(1):409-16. Epub 2008 Mar 10.

Department of Chemistry, Faculty of Science, University of Tanta, 31527 Tanta, Egypt.

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January 2009

Azanonaboranes containing imidazole derivatives for boron neutron capture therapy: synthesis, characterization, and in vitro toxicity evaluation.

Authors:
Mohamed E El-Zaria Afaf R Genady Detlef Gabel

Chemistry 2006 Oct;12(31):8084-9

Department of Chemistry, Faculty of Science, University of Tanta, 31527 Tanta, Egypt.

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October 2006

Synthesis and characterization of a novel functionalized azanonaborane cluster for boron neutron capture therapy.

Authors:
Afaf R Genady

Org Biomol Chem 2005 Jun 29;3(11):2102-8. Epub 2005 Apr 29.

Department of Chemistry, Faculty of Science, University of Tanta, 31527 Tanta, Egypt.

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June 2005