Publications by authors named "Adriano Santorelli"

12 Publications

  • Page 1 of 1

Mid-face reshaping using threads with bidirectional convergent barbs: A retrospective study.

J Cosmet Dermatol 2021 Feb 28. Epub 2021 Feb 28.

Academy of Aesthetic Sciences, Naples, Italy.

Background: Minimally invasive procedures, such as thread suspension techniques, are a growing trend for facial rejuvenation. However, not enough data are available on the efficacy, outcomes, and morbidity of suture suspension techniques in mid-face reshaping.

Aims: Our goal was to assess treatment outcomes and patient satisfaction following mid-face reshaping using threads with bidirectional convergent barbs (Definisse free floating threads).

Patients/methods: We performed a retrospective analysis of 60 patients who underwent treatment for mid-face reshaping using Definisse free floating threads. Response to treatment was assessed at 6 months using the mid-face-specific Mid-Face Volume Deficit scale (Allergan ), Global Aesthetic Improvement and FACE-QTM scales.

Results: Sixty patients underwent mid-face treatment with the suspension thread technique (mean age 51.3, 90% female). No concomitant procedures were done. A reduction by one point or more in the Mid-Face Volume Deficit Scale (MDFVS) score treatment was seen in all patients after 6 months. Mean overall MFVDS and FACE-Q scores were significantly improved. On the GAIS, most patients were rated as improved or better both by the evaluating investigators and during self-assessment. No major complications were observed, and none of the patients requested the removal of the threads (mean follow-up 9.8 months, range 6-14 months).

Conclusion: Our results suggest that mid-face reshaping with Definisse free floating threads is a safe and reliable procedure characterized by low complication rates and good esthetic results. This minimally invasive procedure is a good alternative for normal or combination skin patients who refuse or want to delay the need for traditional rhytidectomy.
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http://dx.doi.org/10.1111/jocd.14038DOI Listing
February 2021

Bleeding in Plastic-Aesthetic Surgery: A Prognostic Pathway with Clinical Application.

Aesthetic Plast Surg 2020 10 27;44(5):1897. Epub 2020 Apr 27.

Plastic Surgery, Academy of Aesthetic Sciences, Napoli, Italy.

Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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http://dx.doi.org/10.1007/s00266-020-01719-wDOI Listing
October 2020

Non-surgical Rhinoplasty with Hyaluronic acid Fillers: Predictable Results Using Software for the Evaluation of Nasal Angles.

Aesthetic Plast Surg 2020 06 12;44(3):919-926. Epub 2019 Dec 12.

Clinica Grimaldi, S. Giorgio a Cremano, Naples, Italy.

Background: There is a relative lack of evidence on optimal products and techniques for nose treatment with hyaluronic acid (HA) fillers. This study assessed the efficacy and safety of nasal reshaping with Vycross HA fillers, using a free software (Face Master) to measure facial parameters.

Methods: This was a prospective, open-label, single-center study of consecutive adult patients treated in the nose (bony and cartilaginous dorsum and/or columella) with VYC-20 or VYC-17.5. A maximum of 1 mL of filler was used. All patients (except one) had at least 12 months of follow-up.

Results: Sixty-two patients were enrolled (57 females; 5 males) with a mean age of 29.0 ± 9.2 years. A mean of 0.55 ± 0.22 mL of filler (range 0.2-1.0 mL) was injected during initial treatment; 12 patients required touch-up with 0.15 ± 0.08 mL of filler (range 0.1-0.3 mL). Using Face Master, mean nasofrontal angle increased from 143.6 ± 6.3° pre-treatment to 147.3 ± 6.7° post-treatment (mean change 3.7 ± 2.8°), and mean nasolabial angle increased from 85.3 ± 6.1° to 88.5 ± 6.1° (mean change 3.2 ± 2.6°). Mean patient satisfaction (0-10 scale) increased from 2.4 ± 1.7 pre-treatment to 9.4 ± 0.8 post-treatment (mean improvement 7.1 ± 2.1). Complications were minor and transient: pain, n = 3 (4.8%); edema, n = 3 (4.8%); hematoma, n = 2 (3.2%).

Conclusions: Non-surgical nasal reshaping with VYC-20 or VYC-17.5 appeared to be efficacious and safe; Face Master objectively demonstrated meaningful changes in key nasal angles.

Level Of Evidence Iv: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
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http://dx.doi.org/10.1007/s00266-019-01579-zDOI Listing
June 2020

Bleeding in Plastic-Aesthetic Surgery: A Prognostic Pathway with Clinical Application.

Aesthetic Plast Surg 2020 02 10;44(1):201-206. Epub 2019 Dec 10.

Plastic Surgery, Academy of Aesthetic Sciences, Naples, Italy.

One of the potential complications of aesthetic surgery is bleeding. Given the high surgical activity carried out in our center and the variety of interventions performed, the risk of bleeding is not negligible: A clinical practice that could reduce this postsurgical complication is necessary. The goal of this article is to value effectiveness of a bleeding score obtained through the evaluation of anamnestic data. The study was divided into two steps. The preliminary data consist in the creation of a form for the evaluation of the bleeding score based on literary data. Subsequently, the first step was put on a retrospective study on 163 patients who underwent aesthetic surgery from January 2013 to July 2017. In the second step, the bleeding score was introduced in clinical practice, submitting the form to 223 patients operated on from September 2017 to September 2018. Retrospective results showed that patients with a low bleeding index had no hemorrhagic complications. One patient of three with a medium-high bleeding score showed a hemorrhagic complication in the postoperative course. The prospective study showed that in three patients with an index between 4 and 7, the level II panel analysis confirmed a medium risk of incurring bleeding episodes during or after the surgery. One patient in 223 obtained a bleeding index of 9: This patient was not operated on and he was sent to the reference center for further investigation. This routine will help to recognize, manage, and prevent hemorrhagic complications of aesthetic surgery.Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
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http://dx.doi.org/10.1007/s00266-019-01557-5DOI Listing
February 2020

Invited Response on: "Does Standardized Practice Reduce Complications in Breast Augmentation Compared with Non-standardized One?"

Aesthetic Plast Surg 2019 10 1;43(5):1417-1418. Epub 2019 Jul 1.

Department of Plastic, Reconstructive and Aesthetic Surgery, "Campus Bio-Medico" University of Rome, Naples, Italy.

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http://dx.doi.org/10.1007/s00266-019-01429-yDOI Listing
October 2019

Minimizing Breast Implant Contamination in Breast Reconstruction Procedures: Introducing the "12 Breast Reconstruction Points".

Plast Reconstr Surg Glob Open 2018 Dec 14;6(12):e2028. Epub 2018 Dec 14.

Department of Plastic, Reconstructive and Aesthetic Surgery, "Campus Bio-Medico" University of Rome, Italy.

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http://dx.doi.org/10.1097/GOX.0000000000002028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326614PMC
December 2018

Standardized Practice Reduces Complications in Breast Augmentation: Results with the First 290 Consecutive Cases Versus Non-standardized Comparators.

Aesthetic Plast Surg 2019 04 12;43(2):336-347. Epub 2018 Dec 12.

Plastic Surgery, Health Park, Via Michelangelo Schipa 40, 80122, Naples, Italy.

Background: Several systematic methods for breast augmentation have been published, providing key principles and technical steps for minimizing complications and optimizing patient satisfaction. The aim of this study was to compare complication rates in patients receiving a breast augmentation performed using a structured, standardized approach versus comparator patients operated on without a standardized approach.

Methods: This was a single-center, retrospective review of 290 consecutive breast augmentations performed between October 2016 and September 2017 based on a standardized technique (Randquist's "five P's" combined with Adams' 14-point plan), and 235 comparators who underwent breast augmentations prior to standardization between April 2014 and September 2016. All study subjects were females aged ≥ 18 years, undergoing bilateral breast augmentation, either alone or in the context of augmentation mastopexy or implant replacement. Various implant ranges were used before standardization; most (94.8%) of the standardized procedures used Natrelle devices. Follow-up lasted for ≥ 12 months.

Results: Significantly fewer patients in the standardized surgery group experienced complications (14.5%, n = 42) compared with the non-standardized group [29.4%, n = 69; Chi square = 6.57; degrees of freedom (df) = 1; p = 0.01041]. Complication rates were also significantly lower in the standardized surgery group for each of the three types of breast augmentation surgery assessed separately. Reoperation rates with standardized and non-standardized surgery were 4.1% (n = 12) and 11.9% (n = 28), respectively (Chi square = 6.4; df = 1; p = 0.01145). Patient satisfaction was increased post-surgery in both groups.

Conclusions: The use of a structured, standardized approach to breast augmentation reduced the risk of postoperative complications.

Level Of Evidence Iv: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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http://dx.doi.org/10.1007/s00266-018-1291-yDOI Listing
April 2019

MBN 2016 Aesthetic Breast Meeting BIA-ALCL Consensus Conference Report.

Plast Reconstr Surg 2018 12;142(6):968e-969e

CETAC Diagnostic and Research Center, Caserta, Italy.

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http://dx.doi.org/10.1097/PRS.0000000000005015DOI Listing
December 2018

Use of Complementary and Alternative Medicine (CAM) in cancer patients: An Italian multicenter survey.

Oncotarget 2017 Apr;8(15):24401-24414

Division of Medical Oncology, Department of Uro-Gynaecological Oncology, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", Naples, Italy.

Introduction: Complementary and Alternative Medicine (CAM) include a wide range of products (herbs, vitamins, minerals, and probiotics) and medical practices, developed outside of the mainstream Western medicine. Patients with cancer are more likely to resort to CAM first or then in their disease history; the potential side effects as well as the costs of such practices are largely underestimated.

Patients And Method: We conducted a descriptive survey in five Italian hospitals involving 468 patients with different malignancies. The survey consisted of a forty-two question questionnaire, patients were eligible if they were Italian-speaking and receiving an anticancer treatment at the time of the survey or had received an anticancer treatment no more than three years before participating in the survey.

Results: Of our patients, 48.9% said they use or have recently used CAM. The univariate analysis showed that female gender, high education, receiving treatment in a highly specialized institute and receiving chemotherapy are associated with CAM use; at the multivariate analysis high education (Odds Ratio, (OR): 1.96 95% Confidence Interval, CI, 1.27-3.05) and receiving treatment in a specialized cancer center (OR: 2.75 95% CI, 1.53-4.94) were confirmed as risk factors for CAM use.

Conclusion: Roughly half of our patients receiving treatment for cancer use CAM. It is necessary that health professional explore the use of CAM with their cancer patients, educate them about potentially beneficial therapies in light of the limited available evidence of effectiveness, and work towards an integrated model of health-care provision.
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http://dx.doi.org/10.18632/oncotarget.14224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421857PMC
April 2017

Use of Macrolane VRF 30 in emicircumferential penis enlargement.

Aesthet Surg J 2013 Feb;33(2):258-64

Department of Plastic Surgery, University Federico II, Naples, Italy.

Background: Penis enlargement is increasingly in demand. Methods for penis enlargement can be classified into surgical, nonsurgical (filling), and mechanical. Each method has shown only relatively successful results. A new formulation of injectable, stabilized, hyaluronic acid (HA)-based, nonanimal gel is available that may have applications for this use.

Objectives: The authors propose a new technique for emicircumferential-injection filling of the penis and assess the safety and efficacy of this procedure compared with lipofilling.

Methods: The authors retrospectively reviewed the charts of 83 patients who underwent penis enlargement with either their HA-injection technique or lipofilling between December 2007 and July 2011. Safety, efficacy, and patient satisfaction were assessed.

Results: The circumferential enlargement obtained from both techniques ranged from 3.2 to 4.5 cm, with a decrement during erection. In all patients, the increase in penis length ranged from 1.8 to 3.6 cm. No complications were seen in patients treated with HA, whereas 8 patients treated with lipofilling developed granuloma, and another experienced fat necrosis. The vast majority (n = 72) of patients reported being "very satisfied" with the results.

Conclusions: The ideal technique for penis enlargement should be nonsurgical, with a satisfactory and predictable result, a low rate of complications, and long-term stability. Emicircumferential enlargement with HA filler meets these requirements. However, results have been durable but not definitive, and repeated treatment (with associated costs) is necessary.
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http://dx.doi.org/10.1177/1090820X12472337DOI Listing
February 2013

Versatility of the posterior auricular flap in partial ear reconstruction.

Plast Reconstr Surg 2010 Oct;126(4):1213-1221

Naples, Italy From the Department of Plastic Surgery, University Federico II.

Background: The posterior auricular flap alone has always been popular because of its prompt availability, its rich vascularity, and the ease of closing the donor-site defect primarily.

Methods: Fifty-seven patients with partial ear defects covered with posterior auricular flaps during the period between 2002 and 2007 were reviewed. In the authors' series, posterior auricular flaps were harvested based on a simple random vascularization and tailored to reach almost any defect of the ear by a simplified and standardized approach.

Results: The authors propose a simple nomenclature after grouping the flaps according to skin paddle type, pedicle type, pedicle base, flap transfer method, and flap movement; they present a standardized algorithm with which to choose the flap design for a given defect from this group.

Conclusions: The authors contribute three new flap designs to enhance the versatility of the posterior auricular flap. These are the superiorly and inferiorly based twisted island flaps and the posterior auricular propeller flap.
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http://dx.doi.org/10.1097/PRS.0b013e3181ec1f03DOI Listing
October 2010

Surgical correction of a mild helical rim deformity.

Plast Reconstr Surg 2010 Apr;125(4):154e-155e

Department of Plastic Surgery; University Federico II; Naples, Italy.

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http://dx.doi.org/10.1097/PRS.0b013e3181d45d42DOI Listing
April 2010