Adriano G Rossi

Adriano G Rossi

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Adriano G Rossi

Publications by authors named "Adriano G Rossi"

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Resolution of Inflammation and Gut Repair in IBD: Translational Steps Towards Complete Mucosal Healing.

Inflamm Bowel Dis 2020 Mar 31. Epub 2020 Mar 31.

Edinburgh IBD Science Unit, Centre for Inflammation Research, Queen's Medical Research Unit, University of Edinburgh, Scotland, United Kingdom.

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http://dx.doi.org/10.1093/ibd/izaa045DOI Listing
March 2020

Assessment of Neutrophil Apoptosis.

Methods Mol Biol 2020 ;2087:167-190

Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1007/978-1-0716-0154-9_13DOI Listing
January 2020

Adaptive prospective optical gating enables day-long 3D time-lapse imaging of the beating embryonic zebrafish heart.

Nat Commun 2019 11 15;10(1):5173. Epub 2019 Nov 15.

British Heart Foundation Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1038/s41467-019-13112-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858381PMC
November 2019

Regulation of Apoptotic Cell Clearance During Resolution of Inflammation.

Front Pharmacol 2019 13;10:891. Epub 2019 Aug 13.

Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.3389/fphar.2019.00891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701246PMC
August 2019

Neutrophils in the initiation and resolution of acute pulmonary inflammation: understanding biological function and therapeutic potential.

J Pathol 2019 04 15;247(5):672-685. Epub 2019 Feb 15.

The University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.

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http://doi.wiley.com/10.1002/path.5221
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http://dx.doi.org/10.1002/path.5221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492013PMC
April 2019

Repurposing simvastatin as a therapy for preterm labor: evidence from preclinical models.

FASEB J 2019 02 12;33(2):2743-2758. Epub 2018 Oct 12.

Tommy's Centre for Maternal and Fetal Health, Medical Research Council (MRC) Centre for Reproductive Health, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom; and.

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https://www.fasebj.org/doi/10.1096/fj.201801104R
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http://dx.doi.org/10.1096/fj.201801104RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338657PMC
February 2019

Inflammation Resolution and the Induction of Granulocyte Apoptosis by Cyclin-Dependent Kinase Inhibitor Drugs.

Front Pharmacol 2019 19;10:55. Epub 2019 Feb 19.

Queen's Medical Research Institute, University of Edinburgh Centre for Inflammation Research, Edinburgh BioQuarter, Edinburgh, United Kingdom.

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http://dx.doi.org/10.3389/fphar.2019.00055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389705PMC
February 2019

Mer-mediated eosinophil efferocytosis regulates resolution of allergic airway inflammation.

J Allergy Clin Immunol 2018 12 8;142(6):1884-1893.e6. Epub 2018 Feb 8.

MRC Centre for Inflammation Research, the Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2018.01.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281028PMC
December 2018

Validation of the Incremental Shuttle Walk Test as a Clinical End Point in Bronchiectasis.

Chest 2018 12 6;154(6):1321-1329. Epub 2018 Oct 6.

MRC Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, United Kingdom; Department of Respiratory Medicine, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S00123692183255
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http://dx.doi.org/10.1016/j.chest.2018.09.019DOI Listing
December 2018

Immune complex-induced neutrophil functions: A focus on cell death.

Eur J Clin Invest 2018 Nov 22;48 Suppl 2:e12948. Epub 2018 May 22.

The MRC Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1111/eci.12948DOI Listing
November 2018

Purine metabolism controls innate lymphoid cell function and protects against intestinal injury.

Immunol Cell Biol 2018 11 10;96(10):1049-1059. Epub 2018 Jul 10.

Medical Research Council (MRC) Centre for Inflammation Research, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, EH16 4TJ, UK.

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http://dx.doi.org/10.1111/imcb.12167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248310PMC
November 2018

Augmentation of Human Monocyte Responses to Lipopolysaccharide by the Protein S and Mer/Tyro3 Receptor Tyrosine Kinase Axis.

J Immunol 2018 11 24;201(9):2602-2611. Epub 2018 Sep 24.

Medical Research Council Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, United Kingdom; and

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http://dx.doi.org/10.4049/jimmunol.1800249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201838PMC
November 2018

Blood Neutrophils Are Reprogrammed in Bronchiectasis.

Am J Respir Crit Care Med 2018 10;198(7):880-890

1 MRC Centre for Inflammation Research at the University of Edinburgh, Queen's Medical Research Institute, Edinburgh, United Kingdom; and.

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http://dx.doi.org/10.1164/rccm.201712-2423OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173062PMC
October 2018

Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD.

Inflamm Bowel Dis 2018 09;24(10):2113-2122

MRC Centre for Inflammation Research, Queens Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.

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https://academic.oup.com/ibdjournal/article/24/10/2113/49872
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http://dx.doi.org/10.1093/ibd/izy095DOI Listing
September 2018

Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-κB activation.

Cell Death Dis 2018 06 4;9(6):665. Epub 2018 Jun 4.

The MRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.

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http://www.nature.com/articles/s41419-018-0710-y
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http://dx.doi.org/10.1038/s41419-018-0710-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986789PMC
June 2018

Prostaglandin E stimulates adaptive IL-22 production and promotes allergic contact dermatitis.

J Allergy Clin Immunol 2018 01 3;141(1):152-162. Epub 2017 Jun 3.

Medical Research Council (MRC) Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.04.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626002PMC
January 2018

Endometrial apoptosis and neutrophil infiltration during menstruation exhibits spatial and temporal dynamics that are recapitulated in a mouse model.

Sci Rep 2017 12 12;7(1):17416. Epub 2017 Dec 12.

MRC Centre for Reproductive Health (CRH), University of Edinburgh, The Queen's Medical Research Institute (QMRI), 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.

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http://dx.doi.org/10.1038/s41598-017-17565-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727295PMC
December 2017

The "Phagocytic Synapse" and Clearance of Apoptotic Cells.

Front Immunol 2017 4;8:1708. Epub 2017 Dec 4.

MRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.3389/fimmu.2017.01708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723006PMC
December 2017

A Randomized Controlled Trial of Atorvastatin in Patients With Bronchiectasis Infected With Pseudomonas Aeruginosa: A Proof of Concept Study.

Chest 2017 08 26;152(2):368-378. Epub 2017 May 26.

University of Edinburgh/MRC Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, Scotland; Royal Infirmary of Edinburgh, Edinburgh, Scotland.

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http://dx.doi.org/10.1016/j.chest.2017.05.017DOI Listing
August 2017

Genetic and pharmacological inhibition of CDK9 drives neutrophil apoptosis to resolve inflammation in zebrafish in vivo.

Sci Rep 2016 11 11;5:36980. Epub 2016 Nov 11.

MRC Centre for Inflammation Research, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, EH16 4TJ, United Kingdom.

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http://www.nature.com/articles/srep36980
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http://dx.doi.org/10.1038/srep36980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105078PMC
November 2016

Non-canonical PI3K-Cdc42-Pak-Mek-Erk Signaling Promotes Immune-Complex-Induced Apoptosis in Human Neutrophils.

Cell Rep 2016 10;17(2):374-386

The MRC Centre for Inflammation Research, Queen's Medical Research Institute, 47 Little France Crescent, University of Edinburgh, Edinburgh EH16 4TJ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067281PMC
October 2016

Systemic inflammation after critical illness: relationship with physical recovery and exploration of potential mechanisms.

Thorax 2016 09 26;71(9):820-9. Epub 2016 Apr 26.

Department of Anaesthesia, Critical Care and Pain Medicine, University of Edinburgh, Edinburgh, UK MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK Department of Critical Care, Royal Infirmary of Edinburgh, NHS Lothian, Edinburgh, UK.

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http://dx.doi.org/10.1136/thoraxjnl-2015-208114DOI Listing
September 2016

11β-Hydroxysteroid Dehydrogenase Type 1 Is Expressed in Neutrophils and Restrains an Inflammatory Response in Male Mice.

Endocrinology 2016 07 4;157(7):2928-36. Epub 2016 May 4.

Centre for Cardiovascular Science (A.E.C., T.M.J.K., Z.Z., C.L.E., J.S.G., S.P.W., B.R.W., J.R.S., K.E.C.) and Medical Research Council Centre for Inflammation Research (A.E.C., C.D.L., J.S.G., J.H., J.S.S., A.G.R.), Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, United Kingdom.

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http://dx.doi.org/10.1210/en.2016-1118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929552PMC
July 2016

Models for the Study of the Cross Talk Between Inflammation and Cell Cycle.

Methods Mol Biol 2016 ;1336:179-209

MRC Centre for Inflammation Research, The Queen's Medical Research Institute, The University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.

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http://dx.doi.org/10.1007/978-1-4939-2926-9_15DOI Listing
May 2016

The role of neutrophils in inflammation resolution.

Semin Immunol 2016 04 24;28(2):137-45. Epub 2016 Mar 24.

MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh Medical School, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1016/j.smim.2016.03.007DOI Listing
April 2016

Neutrophil-derived alpha defensins control inflammation by inhibiting macrophage mRNA translation.

Proc Natl Acad Sci U S A 2016 Apr 4;113(16):4350-5. Epub 2016 Apr 4.

MRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, Scotland;

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http://dx.doi.org/10.1073/pnas.1601831113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843457PMC
April 2016

Mechanism of neutrophil activation and toxicity elicited by engineered nanomaterials.

Toxicol In Vitro 2015 Aug 8;29(5):1172-84. Epub 2015 May 8.

School of Life Sciences, Heriot-Watt University, Edinburgh EH14 4AS, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S08872333150009
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http://dx.doi.org/10.1016/j.tiv.2015.04.021DOI Listing
August 2015

The role of formylated peptides and formyl peptide receptor 1 in governing neutrophil function during acute inflammation.

Am J Pathol 2015 May 17;185(5):1172-84. Epub 2015 Mar 17.

Medical Research Council Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh Medical School, Edinburgh, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S00029440150008
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http://dx.doi.org/10.1016/j.ajpath.2015.01.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419282PMC
May 2015

Wogonin induces eosinophil apoptosis and attenuates allergic airway inflammation.

Am J Respir Crit Care Med 2015 Mar;191(6):626-36

MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh Medical School, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1164/rccm.201408-1565OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384778PMC
March 2015

Assays of eosinophil apoptosis and phagocytic uptake.

Methods Mol Biol 2014 ;1178:177-95

MRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Room W2.04, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.

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http://dx.doi.org/10.1007/978-1-4939-1016-8_16DOI Listing
February 2015

Assessment of neutrophil apoptosis.

Methods Mol Biol 2014 ;1124:159-80

MRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1007/978-1-62703-845-4_10DOI Listing
October 2014

Leukoreduced blood transfusion does not increase circulating soluble markers of inflammation: a randomized controlled trial.

Transfusion 2014 Oct 5;54(10):2404-11. Epub 2014 May 5.

Anaesthetics and Critical Care, Royal Infirmary of Edinburgh and the MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1111/trf.12669DOI Listing
October 2014

Functional characterisation of human pulmonary monocyte-like cells in lipopolysaccharide-mediated acute lung inflammation.

J Inflamm (Lond) 2014 31;11. Epub 2014 Mar 31.

Medical Research Council Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK ; Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1186/1476-9255-11-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032498PMC
August 2014

Invertebrate extracellular phagocyte traps show that chromatin is an ancient defence weapon.

Nat Commun 2014 Aug 13;5:4627. Epub 2014 Aug 13.

Scottish Oceans Institute, School of Biology, University of St Andrews, St Andrews, Scotland KY16 8LB, UK.

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http://dx.doi.org/10.1038/ncomms5627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143918PMC
August 2014

Eosinophils in the lung - modulating apoptosis and efferocytosis in airway inflammation.

Front Immunol 2014 1;5:302. Epub 2014 Jul 1.

MRC Centre for Inflammation Research, Queen's Medical Research Institute, The University of Edinburgh , Edinburgh , UK.

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http://dx.doi.org/10.3389/fimmu.2014.00302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076794PMC
July 2014

Atorvastatin as a stable treatment in bronchiectasis: a randomised controlled trial.

Lancet Respir Med 2014 Jun 24;2(6):455-63. Epub 2014 Mar 24.

University of Edinburgh/MRC Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, UK; Department of Respiratory Medicine, Royal Infirmary of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/S2213-2600(14)70050-5DOI Listing
June 2014

Apoptotic cell clearance: basic biology and therapeutic potential.

Nat Rev Immunol 2014 Mar 31;14(3):166-80. Epub 2014 Jan 31.

Center for Cell Clearance and the Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia 22908, USA.

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http://www.nature.com/articles/nri3607
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http://dx.doi.org/10.1038/nri3607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040260PMC
March 2014

Decidual neutrophil infiltration is not required for preterm birth in a mouse model of infection-induced preterm labor.

J Immunol 2014 Mar 5;192(5):2315-25. Epub 2014 Feb 5.

Medical Research Council Centre for Reproductive Health, University of Edinburgh, Queen's Medical Research Institute, Edinburgh EH16 4TJ, United Kingdom;

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http://dx.doi.org/10.4049/jimmunol.1302891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932811PMC
March 2014

Swimming against the tide: drugs drive neutrophil reverse migration.

Sci Transl Med 2014 Feb;6(225):225fs9

MRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh Medical School, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland.

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http://dx.doi.org/10.1126/scitranslmed.3008666DOI Listing
February 2014

Oxygen levels determine the ability of glucocorticoids to influence neutrophil survival in inflammatory environments.

J Leukoc Biol 2013 Dec 20;94(6):1285-92. Epub 2013 Aug 20.

1.The Queen's Medical Research Institute, University of Edinburgh Medical School, 47 Little France Crescent, Edinburgh, EH16 4TJ, Scotland, UK.

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http://dx.doi.org/10.1189/jlb.0912462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855024PMC
December 2013

Emerging importance of omega-3 fatty acids in the innate immune response: molecular mechanisms and lipidomic strategies for their analysis.

Mol Nutr Food Res 2013 Aug 18;57(8):1390-400. Epub 2013 Feb 18.

Lipidomics Research Facility, Department of Diabetes and Cardiovascular Science, University of the Highlands and Islands, Inverness, UK.

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http://dx.doi.org/10.1002/mnfr.201200723DOI Listing
August 2013

Resolution of inflammation: mechanisms and opportunity for drug development.

Pharmacol Ther 2013 Aug 11;139(2):189-212. Epub 2013 Apr 11.

Medical Research Council Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, United Kingdom.

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http://dx.doi.org/10.1016/j.pharmthera.2013.04.006DOI Listing
August 2013

Novel R-roscovitine NO-donor hybrid compounds as potential pro-resolution of inflammation agents.

Bioorg Med Chem 2013 Apr 16;21(7):2107-16. Epub 2013 Jan 16.

Dipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, Via P. Giuria 9, 10125 Torino, Italy.

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http://dx.doi.org/10.1016/j.bmc.2013.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898921PMC
April 2013

L13. Apoptosis, apoptotic cell clearance and resolution of inflammation.

Authors:
Adriano G Rossi

Presse Med 2013 Apr 6;42(4 Pt 2):536-7. Epub 2013 Mar 6.

MRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 47, Little France Crescent, Edinburgh, EH16 4TJ Scotland, UK.

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http://dx.doi.org/10.1016/j.lpm.2013.01.012DOI Listing
April 2013

Flavones induce neutrophil apoptosis by down-regulation of Mcl-1 via a proteasomal-dependent pathway.

FASEB J 2013 Mar 29;27(3):1084-94. Epub 2012 Nov 29.

MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh Medical School, 47 Little France Crescent, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1096/fj.12-218990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574292PMC
March 2013

Activation of conventional protein kinase C (PKC) is critical in the generation of human neutrophil extracellular traps.

J Inflamm (Lond) 2013 Mar 21;10(1):12. Epub 2013 Mar 21.

MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh Medical School, 47 Little France Crescent, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1186/1476-9255-10-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643828PMC
March 2013

Characterization of the effects of cross-linking of macrophage CD44 associated with increased phagocytosis of apoptotic PMN.

PLoS One 2012 9;7(3):e33142. Epub 2012 Mar 9.

Division of Cardiovascular and Respiratory Studies, Hull York Medical School/University of Hull, Castle Hill Hospital, Hull, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0033142PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302854PMC
August 2012

A novel subpopulation of monocyte-like cells in the human lung after lipopolysaccharide inhalation.

Eur Respir J 2012 Jul 20;40(1):206-14. Epub 2012 Jan 20.

University of Edinburgh MRC Centre for Inflammation Research, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.

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http://dx.doi.org/10.1183/09031936.00113811DOI Listing
July 2012

Leukocyte migratory responses to apoptosis: the attraction and the distraction.

Cell Adh Migr 2011 Jul-Aug;5(4):293-7. Epub 2011 Jul 1.

MRC Centre for Inflammation Research; University of Edinburgh, Queens Medical Research Institute, Edinburgh, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210296PMC
http://dx.doi.org/10.4161/cam.5.4.16743DOI Listing
December 2011

Xanthohumol induces apoptosis in human malignant glioblastoma cells by increasing reactive oxygen species and activating MAPK pathways.

J Nat Prod 2011 Dec 23;74(12):2505-13. Epub 2011 Nov 23.

Dipartimento di Scienze Farmaceutiche e Biomediche, Università degli Studi di Salerno, Via Ponte Don Melillo, 84084 Fisciano, Salerno, Italy.

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http://dx.doi.org/10.1021/np200390xDOI Listing
December 2011

Anti-inflammatory mediators as physiological and pharmacological regulators of parturition.

Expert Rev Clin Immunol 2011 Sep;7(5):675-96

MRC Centre for Reproductive Health, University of Edinburgh, Queen's Medical Research Institute, Edinburgh, EH16 4TJ, UK.

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http://dx.doi.org/10.1586/eci.11.58DOI Listing
September 2011

Mechanisms of resolution of inflammation: a focus on cardiovascular disease.

Arterioscler Thromb Vasc Biol 2011 May;31(5):1001-6

Lipidomic Research Facility, UHI Department of Diabetes and Cardiovascular Science, Highland Diabetes Institute, Centre for Health Science, Old Perth Road, Inverness IV2 3JH, Scotland.

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http://dx.doi.org/10.1161/ATVBAHA.110.213850DOI Listing
May 2011

Differential susceptibility to nitric oxide-evoked apoptosis in human inflammatory cells.

Free Radic Biol Med 2011 Jan 15;50(1):93-101. Epub 2010 Sep 15.

Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK.

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http://dx.doi.org/10.1016/j.freeradbiomed.2010.08.030DOI Listing
January 2011

Neutrophil apoptosis: relevance to the innate immune response and inflammatory disease.

J Innate Immun 2010 11;2(3):216-27. Epub 2010 Feb 11.

MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh Medical School, Edinburgh, UK. sfox1 @ staffmail.ed.ac.uk

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http://dx.doi.org/10.1159/000284367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956014PMC
September 2010

Targeting granulocyte apoptosis: mechanisms, models, and therapies.

Immunol Rev 2010 Jul;236:28-40

MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1111/j.1600-065X.2010.00922.xDOI Listing
July 2010

PDE4 inhibition drives resolution of neutrophilic inflammation by inducing apoptosis in a PKA-PI3K/Akt-dependent and NF-kappaB-independent manner.

J Leukoc Biol 2010 May 26;87(5):895-904. Epub 2010 Jan 26.

Setor de Patologia Clínica-Colégio Técnico, Imunofarmacologia-Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

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http://dx.doi.org/10.1189/jlb.0809540DOI Listing
May 2010

NO-loaded Zn(2+)-exchanged zeolite materials: a potential bifunctional anti-bacterial strategy.

Acta Biomater 2010 Apr 25;6(4):1515-21. Epub 2009 Oct 25.

University of Edinburgh, MRC Centre for Inflammation Research, Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.

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http://dx.doi.org/10.1016/j.actbio.2009.10.038DOI Listing
April 2010

The cyclin-dependent kinase inhibitor R-roscovitine down-regulates Mcl-1 to override pro-inflammatory signalling and drive neutrophil apoptosis.

Eur J Immunol 2010 Apr;40(4):1127-38

MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh Medical School, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1002/eji.200939664DOI Listing
April 2010

Inhibition of eosinophil migration by lactoferrin.

Immunol Cell Biol 2010 Feb 17;88(2):220-3. Epub 2009 Nov 17.

Medical Research Council (MRC) Centre for Inflammation Research, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1038/icb.2009.86DOI Listing
February 2010

Cyclic AMP enhances resolution of allergic pleurisy by promoting inflammatory cell apoptosis via inhibition of PI3K/Akt and NF-kappaB.

Biochem Pharmacol 2009 Aug 5;78(4):396-405. Epub 2009 May 5.

Setor de Patologia Clínica, Colégio Técnico, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

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http://dx.doi.org/10.1016/j.bcp.2009.04.030DOI Listing
August 2009

The CDK inhibitor, R-roscovitine, promotes eosinophil apoptosis by down-regulation of Mcl-1.

FEBS Lett 2009 Aug 18;583(15):2540-6. Epub 2009 Jul 18.

MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh Medical School, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1016/j.febslet.2009.07.017DOI Listing
August 2009

Prostaglandin F2alpha-F-prostanoid receptor signaling promotes neutrophil chemotaxis via chemokine (C-X-C motif) ligand 1 in endometrial adenocarcinoma.

Cancer Res 2009 Jul 23;69(14):5726-33. Epub 2009 Jun 23.

Medical Research Council Human Reproductive Sciences Unit, Department of Reproductive and Developmental Sciences, The Queen's Medical Research Institute, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-0390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712458PMC
July 2009

Cyclic GMP protects human macrophages against peroxynitrite-induced apoptosis.

J Inflamm (Lond) 2009 May 7;6:14. Epub 2009 May 7.

Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1186/1476-9255-6-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689212PMC
May 2009

Enzyme-independent NO stores in human skin: quantification and influence of UV radiation.

J Invest Dermatol 2009 Apr 25;129(4):834-42. Epub 2008 Sep 25.

Department of Dermatology, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1038/jid.2008.296DOI Listing
April 2009

Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro-inflammatory and anti-inflammatory agents: key role for TNF-alpha.

FASEB J 2009 Mar 29;23(3):844-54. Epub 2008 Oct 29.

MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh Medical School, 47 Little France Crescent, Edinburgh, Scotland, EH16 4TJ UK.

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http://dx.doi.org/10.1096/fj.08-121228DOI Listing
March 2009

Highlights of a workshop to discuss targeting inflammation in cystic fibrosis.

J Cyst Fibros 2009 Jan 20;8(1):1-8. Epub 2008 Nov 20.

Novartis Institutes for Biomedical Research, Wimblehurst Road, Horsham, West Sussex, RH12 5AB, UK.

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http://dx.doi.org/10.1016/j.jcf.2008.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133129PMC
January 2009

Apoptotic human cells inhibit migration of granulocytes via release of lactoferrin.

J Clin Invest 2009 Jan 1;119(1):20-32. Epub 2008 Dec 1.

The University of Edinburgh/Medical Research Council (MRC) Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, UK.

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http://dx.doi.org/10.1172/JCI36226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613454PMC
January 2009

A novel hybrid aspirin-NO-releasing compound inhibits TNFalpha release from LPS-activated human monocytes and macrophages.

J Inflamm (Lond) 2008 Jul 31;5:12. Epub 2008 Jul 31.

MRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, EH16 4TJ, UK.

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http://dx.doi.org/10.1186/1476-9255-5-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525633PMC
July 2008

Analysis of neutrophil apoptosis.

Methods Mol Biol 2007 ;412:177-200

MRC/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1007/978-1-59745-467-4_12DOI Listing
June 2008

Novel pharmacological strategies for driving inflammatory cell apoptosis and enhancing the resolution of inflammation.

Trends Pharmacol Sci 2008 May 11;29(5):250-7. Epub 2008 Apr 11.

MRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh Medical School, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S016561470800072
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http://dx.doi.org/10.1016/j.tips.2008.03.002DOI Listing
May 2008

The anti-inflammatory effects and the inhibition of neutrophil responsiveness by Barleria lupulina and Clinacanthus nutans extracts.

J Ethnopharmacol 2008 Mar 5;116(2):234-44. Epub 2007 Dec 5.

Department of Pharmacology, Faculty of Science, Mahidol University, Rama VI Road, Bangkok 10400, Thailand.

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http://linkinghub.elsevier.com/retrieve/pii/S037887410700611
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http://dx.doi.org/10.1016/j.jep.2007.11.035DOI Listing
March 2008

Phagocytosis of apoptotic cells.

Methods 2008 Mar;44(3):280-5

MRC Centre for Inflammation Research, University of Edinburgh, Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.

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http://dx.doi.org/10.1016/j.ymeth.2007.11.009DOI Listing
March 2008

Galectin-3 reduces the severity of pneumococcal pneumonia by augmenting neutrophil function.

Am J Pathol 2008 Feb 17;172(2):395-405. Epub 2008 Jan 17.

Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK.

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http://dx.doi.org/10.2353/ajpath.2008.070870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2312371PMC
February 2008