Adriana I Iglesias

Adriana I Iglesias

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Adriana I Iglesias

Adriana I Iglesias

Publications by authors named "Adriana I Iglesias"

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Multi-trait genome-wide association study identifies new loci associated with optic disc parameters.

Authors:
Pieter W M Bonnemaijer Elisabeth M van Leeuwen Adriana I Iglesias Puya Gharahkhani Veronique Vitart Anthony P Khawaja Mark Simcoe René Höhn Angela J Cree Rob P Igo Aslihan Gerhold-Ay Stefan Nickels James F Wilson Caroline Hayward Thibaud S Boutin Ozren Polašek Tin Aung Chiea Chuen Khor Najaf Amin Andrew J Lotery Janey L Wiggs Ching-Yu Cheng Pirro G Hysi Christopher J Hammond Alberta A H J Thiadens Stuart MacGregor Caroline C W Klaver Cornelia M van Duijn

Commun Biol 2019 27;2:435. Epub 2019 Nov 27.

2Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s42003-019-0634-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881308PMC
November 2019

Interaction between lifestyle and genetic susceptibility in myopia: the Generation R study.

Authors:
Clair A Enthoven Jan Willem Lodewijk Tideman Jan Roelof Polling Milly S Tedja Hein Raat Adriana I Iglesias Virginie J M Verhoeven Caroline C W Klaver

Eur J Epidemiol 2019 Aug 3;34(8):777-784. Epub 2019 Apr 3.

Department of Ophthalmology, Erasmus University Medical Centre, Room Na-2808, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10654-019-00512-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602996PMC
August 2019

Determining Possible Shared Genetic Architecture Between Myopia and Primary Open-Angle Glaucoma.

Authors:
Adriana I Iglesias Jue Sheng Ong Anthony P Khawaja Puya Gharahkhani Milly S Tedja Virginie J M Verhoeven Pieter W M Bonnemaijer Roger C W Wolfs Terri L Young Nomdo M Jansonius Jamie E Craig Dwight Stambolian Cornelia M van Duijn Stuart MacGregor Caroline C W Klaver

Invest Ophthalmol Vis Sci 2019 07;60(8):3142-3149

Department of Ophthalmology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1167/iovs.18-26231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645704PMC
July 2019

Genetic correlations between diabetes and glaucoma: an analysis of continuous and dichotomous phenotypes.

Authors:
Vincent Laville Jae H Kang Clara C Cousins Adriana I Iglesias Réka Nagy Jessica N Cooke Bailey Robert P Igo Yeunjoo E Song Daniel I Chasman William G Christen Peter Kraft Bernard A Rosner Frank Hu James F Wilson Puya Gharahkhani Alex W Hewitt David A Mackey Pirro G Hysi Christopher J Hammond Cornelia M vanDuijn Jonathan L Haines Veronique Vitart John H Fingert Michael A Hauser Hugues Aschard Janey L Wiggs Anthony P Khawaja Stuart MacGregor Louis R Pasquale

Am J Ophthalmol 2019 May 20. Epub 2019 May 20.

Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Icahn School of Medicine at Mount Sinai, Department of Ophthalmology, New York, NY, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029394193024
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http://dx.doi.org/10.1016/j.ajo.2019.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864262PMC
May 2019

Author Correction: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.

Authors:
Adriana I Iglesias Aniket Mishra Veronique Vitart Yelena Bykhovskaya René Höhn Henriët Springelkamp Gabriel Cuellar-Partida Puya Gharahkhani Jessica N Cooke Bailey Colin E Willoughby Xiaohui Li Seyhan Yazar Abhishek Nag Anthony P Khawaja Ozren Polašek David Siscovick Paul Mitchell Yih Chung Tham Jonathan L Haines Lisa S Kearns Caroline Hayward Yuan Shi Elisabeth M van Leeuwen Kent D Taylor Pieter Bonnemaijer Jerome I Rotter Nicholas G Martin Tanja Zeller Richard A Mills Emmanuelle Souzeau Sandra E Staffieri Jost B Jonas Irene Schmidtmann Thibaud Boutin Jae H Kang Sionne E M Lucas Tien Yin Wong Manfred E Beutel James F Wilson André G Uitterlinden Eranga N Vithana Paul J Foster Pirro G Hysi Alex W Hewitt Chiea Chuen Khor Louis R Pasquale Grant W Montgomery Caroline C W Klaver Tin Aung Norbert Pfeiffer David A Mackey Christopher J Hammond Ching-Yu Cheng Jamie E Craig Yaron S Rabinowitz Janey L Wiggs Kathryn P Burdon Cornelia M van Duijn Stuart MacGregor

Nat Commun 2019 01 8;10(1):155. Epub 2019 Jan 8.

Statistical Genetics, QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4029, Australia.

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http://www.nature.com/articles/s41467-018-07819-1
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http://dx.doi.org/10.1038/s41467-018-07819-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325104PMC
January 2019

Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations.

Authors:
Pieter W M Bonnemaijer Adriana I Iglesias Girish N Nadkarni Anna J Sanyiwa Hassan G Hassan Colin Cook Mark Simcoe Kent D Taylor Claudia Schurmann Gillian M Belbin Eimear E Kenny Erwin P Bottinger Suzanne van de Laar Susan E I Wiliams Stephen K Akafo Adeyinka O Ashaye Linda M Zangwill Christopher A Girkin Maggie C Y Ng Jerome I Rotter Robert N Weinreb Zheng Li R Rand Allingham Abhishek Nag Pirro G Hysi Magda A Meester-Smoor Janey L Wiggs Michael A Hauser Christopher J Hammond Hans G Lemij Ruth J F Loos Cornelia M van Duijn Alberta A H J Thiadens Caroline C W Klaver

Hum Genet 2018 Oct 13;137(10):847-862. Epub 2018 Oct 13.

Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00439-018-1943-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754628PMC
October 2018

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.

Authors:
Milly S Tedja Robert Wojciechowski Pirro G Hysi Nicholas Eriksson Nicholas A Furlotte Virginie J M Verhoeven Adriana I Iglesias Magda A Meester-Smoor Stuart W Tompson Qiao Fan Anthony P Khawaja Ching-Yu Cheng René Höhn Kenji Yamashiro Adam Wenocur Clare Grazal Toomas Haller Andres Metspalu Juho Wedenoja Jost B Jonas Ya Xing Wang Jing Xie Paul Mitchell Paul J Foster Barbara E K Klein Ronald Klein Andrew D Paterson S Mohsen Hosseini Rupal L Shah Cathy Williams Yik Ying Teo Yih Chung Tham Preeti Gupta Wanting Zhao Yuan Shi Woei-Yuh Saw E-Shyong Tai Xue Ling Sim Jennifer E Huffman Ozren Polašek Caroline Hayward Goran Bencic Igor Rudan James F Wilson Peter K Joshi Akitaka Tsujikawa Fumihiko Matsuda Kristina N Whisenhunt Tanja Zeller Peter J van der Spek Roxanna Haak Hanne Meijers-Heijboer Elisabeth M van Leeuwen Sudha K Iyengar Jonathan H Lass Albert Hofman Fernando Rivadeneira André G Uitterlinden Johannes R Vingerling Terho Lehtimäki Olli T Raitakari Ginevra Biino Maria Pina Concas Tae-Hwi Schwantes-An Robert P Igo Gabriel Cuellar-Partida Nicholas G Martin Jamie E Craig Puya Gharahkhani Katie M Williams Abhishek Nag Jugnoo S Rahi Phillippa M Cumberland Cécile Delcourt Céline Bellenguez Janina S Ried Arthur A Bergen Thomas Meitinger Christian Gieger Tien Yin Wong Alex W Hewitt David A Mackey Claire L Simpson Norbert Pfeiffer Olavi Pärssinen Paul N Baird Veronique Vitart Najaf Amin Cornelia M van Duijn Joan E Bailey-Wilson Terri L Young Seang-Mei Saw Dwight Stambolian Stuart MacGregor Jeremy A Guggenheim Joyce Y Tung Christopher J Hammond Caroline C W Klaver

Nat Genet 2018 06 28;50(6):834-848. Epub 2018 May 28.

Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://www.nature.com/articles/s41588-018-0127-7
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http://dx.doi.org/10.1038/s41588-018-0127-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980758PMC
June 2018

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.

Authors:
Adriana I Iglesias Aniket Mishra Veronique Vitart Yelena Bykhovskaya René Höhn Henriët Springelkamp Gabriel Cuellar-Partida Puya Gharahkhani Jessica N Cooke Bailey Colin E Willoughby Xiaohui Li Seyhan Yazar Abhishek Nag Anthony P Khawaja Ozren Polašek David Siscovick Paul Mitchell Yih Chung Tham Jonathan L Haines Lisa S Kearns Caroline Hayward Yuan Shi Elisabeth M van Leeuwen Kent D Taylor Pieter Bonnemaijer Jerome I Rotter Nicholas G Martin Tanja Zeller Richard A Mills Emmanuelle Souzeau Sandra E Staffieri Jost B Jonas Irene Schmidtmann Thibaud Boutin Jae H Kang Sionne E M Lucas Tien Yin Wong Manfred E Beutel James F Wilson André G Uitterlinden Eranga N Vithana Paul J Foster Pirro G Hysi Alex W Hewitt Chiea Chuen Khor Louis R Pasquale Grant W Montgomery Caroline C W Klaver Tin Aung Norbert Pfeiffer David A Mackey Christopher J Hammond Ching-Yu Cheng Jamie E Craig Yaron S Rabinowitz Janey L Wiggs Kathryn P Burdon Cornelia M van Duijn Stuart MacGregor

Nat Commun 2018 05 14;9(1):1864. Epub 2018 May 14.

Statistical Genetics, QIMR Berghofer Medical Research Institute, QLD 4029, Brisbane, Australia.

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http://dx.doi.org/10.1038/s41467-018-03646-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951816PMC
May 2018

A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy.

Authors:
Claudia Tamar Silva Irina V Zorkoltseva Maartje N Niemeijer Marten E van den Berg Najaf Amin Ayşe Demirkan Elisa van Leeuwen Adriana I Iglesias Laura B Piñeros-Hernández Carlos M Restrepo Jan A Kors Anatoly V Kirichenko Rob Willemsen Ben A Oostra Bruno H Stricker André G Uitterlinden Tatiana I Axenovich Cornelia M van Duijn Aaron Isaacs

BMC Med Genomics 2018 03 5;11(1):22. Epub 2018 Mar 5.

Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1186/s12920-018-0339-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838853PMC
March 2018

Genetic correlations between intraocular pressure, blood pressure and primary open-angle glaucoma: a multi-cohort analysis.

Authors:
Hugues Aschard Jae H Kang Adriana I Iglesias Pirro Hysi Jessica N Cooke Bailey Anthony P Khawaja R Rand Allingham Allison Ashley-Koch Richard K Lee Sayoko E Moroi Murray H Brilliant Gadi Wollstein Joel S Schuman John H Fingert Donald L Budenz Tony Realini Terry Gaasterland William K Scott Kuldev Singh Arthur J Sit Robert P Igo Yeunjoo E Song Lisa Hark Robert Ritch Douglas J Rhee Vikas Gulati Shane Haven Douglas Vollrath Donald J Zack Felipe Medeiros Robert N Weinreb Ching-Yu Cheng Daniel I Chasman William G Christen Margaret A Pericak-Vance Yutao Liu Peter Kraft Julia E Richards Bernard A Rosner Michael A Hauser Caroline C W Klaver Cornelia M vanDuijn Jonathan Haines Janey L Wiggs Louis R Pasquale

Eur J Hum Genet 2017 11 30;25(11):1261-1267. Epub 2017 Aug 30.

Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://www.nature.com/doifinder/10.1038/ejhg.2017.136
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http://dx.doi.org/10.1038/ejhg.2017.136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643970PMC
November 2017

A Genome-Wide Scan for MicroRNA-Related Genetic Variants Associated With Primary Open-Angle Glaucoma.

Authors:
Mohsen Ghanbari Adriana I Iglesias Henriët Springelkamp Cornelia M van Duijn M Arfan Ikram Abbas Dehghan Stefan J Erkeland Caroline C W Klaver Magda A Meester-Smoor

Invest Ophthalmol Vis Sci 2017 10;58(12):5368-5377

Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1167/iovs.17-22410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110129PMC
October 2017

Haplotype reference consortium panel: Practical implications of imputations with large reference panels.

Authors:
Adriana I Iglesias Sven J van der Lee Pieter W M Bonnemaijer René Höhn Abhishek Nag Puya Gharahkhani Anthony P Khawaja Linda Broer Paul J Foster Christopher J Hammond Pirro G Hysi Elisabeth M van Leeuwen Stuart MacGregor David A Mackey Johanna Mazur Stefan Nickels André G Uitterlinden Caroline C W Klaver Najaf Amin Cornelia M van Duijn

Hum Mutat 2017 08 9;38(8):1025-1032. Epub 2017 Jun 9.

Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1002/humu.23247DOI Listing
August 2017

Evaluation of the Myocilin Mutation Gln368Stop Demonstrates Reduced Penetrance for Glaucoma in European Populations.

Authors:
Abhishek Nag Han Lu Matthew Arno Adriana I Iglesias Pieter Bonnemaijer Linda Broer Andre G Uitterlinden Caroline C W Klaver Cornelia van Duijn Pirro G Hysi Christopher J Hammond

Ophthalmology 2017 04 27;124(4):547-553. Epub 2016 Dec 27.

Department of Twin Research and Genetic Epidemiology, King's College London, St. Thomas' Hospital, London, United Kingdom; Department of Ophthalmology, King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2016.11.018DOI Listing
April 2017

New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.

Authors:
Henriët Springelkamp Adriana I Iglesias Aniket Mishra René Höhn Robert Wojciechowski Anthony P Khawaja Abhishek Nag Ya Xing Wang Jie Jin Wang Gabriel Cuellar-Partida Jane Gibson Jessica N Cooke Bailey Eranga N Vithana Puya Gharahkhani Thibaud Boutin Wishal D Ramdas Tanja Zeller Robert N Luben Ekaterina Yonova-Doing Ananth C Viswanathan Seyhan Yazar Angela J Cree Jonathan L Haines Jia Yu Koh Emmanuelle Souzeau James F Wilson Najaf Amin Christian Müller Cristina Venturini Lisa S Kearns Jae Hee Kang Yih Chung Tham Tiger Zhou Elisabeth M van Leeuwen Stefan Nickels Paul Sanfilippo Jiemin Liao Herma van der Linde Wanting Zhao Leonieke M E van Koolwijk Li Zheng Fernando Rivadeneira Mani Baskaran Sven J van der Lee Shamira Perera Paulus T V M de Jong Ben A Oostra André G Uitterlinden Qiao Fan Albert Hofman E-Shyong Tai Johannes R Vingerling Xueling Sim Roger C W Wolfs Yik Ying Teo Hans G Lemij Chiea Chuen Khor Rob Willemsen Karl J Lackner Tin Aung Nomdo M Jansonius Grant Montgomery Philipp S Wild Terri L Young Kathryn P Burdon Pirro G Hysi Louis R Pasquale Tien Yin Wong Caroline C W Klaver Alex W Hewitt Jost B Jonas Paul Mitchell Andrew J Lotery Paul J Foster Veronique Vitart Norbert Pfeiffer Jamie E Craig David A Mackey Christopher J Hammond Janey L Wiggs Ching-Yu Cheng Cornelia M van Duijn Stuart MacGregor

Hum Mol Genet 2017 01;26(2):438-453

Statistical Genetics, QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Brisbane, Australia.

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http://dx.doi.org/10.1093/hmg/ddw399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968632PMC
January 2017

Associations with intraocular pressure across Europe: The European Eye Epidemiology (E) Consortium.

Authors:
Anthony P Khawaja Henriët Springelkamp Catherine Creuzot-Garcher Cécile Delcourt Albert Hofman René Höhn Adriana I Iglesias Roger C W Wolfs Jean-François Korobelnik Rufino Silva Fotis Topouzis Katie M Williams Alain M Bron Gabriëlle H S Buitendijk Maria da Luz Cachulo Audrey Cougnard-Grégoire Jean-François Dartigues Christopher J Hammond Norbert Pfeiffer Angeliki Salonikiou Cornelia M van Duijn Johannes R Vingerling Robert N Luben Alireza Mirshahi Julia Lamparter Caroline C W Klaver Nomdo M Jansonius Paul J Foster

Eur J Epidemiol 2016 11 9;31(11):1101-1111. Epub 2016 Sep 9.

NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.

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http://link.springer.com/10.1007/s10654-016-0191-1
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http://dx.doi.org/10.1007/s10654-016-0191-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206267PMC
November 2016

WNT10A exonic variant increases the risk of keratoconus by decreasing corneal thickness.

Authors:
Gabriel Cuellar-Partida Henriët Springelkamp Sionne E M Lucas Seyhan Yazar Alex W Hewitt Adriana I Iglesias Grant W Montgomery Nicholas G Martin Craig E Pennell Elisabeth M van Leeuwen Virginie J M Verhoeven Albert Hofman André G Uitterlinden Wishal D Ramdas Roger C W Wolfs Johannes R Vingerling Matthew A Brown Richard A Mills Jamie E Craig Caroline C W Klaver Cornelia M van Duijn Kathryn P Burdon Stuart MacGregor David A Mackey

Hum Mol Genet 2015 Sep 5;24(17):5060-8. Epub 2015 Jun 5.

Centre for Ophthalmology and Visual Science, Lions Eye Institute, University of Western Australia.

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http://hmg.oxfordjournals.org/content/early/2015/06/20/hmg.d
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http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddv
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http://dx.doi.org/10.1093/hmg/ddv211DOI Listing
September 2015

ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure.

Authors:
Henriët Springelkamp Adriana I Iglesias Gabriel Cuellar-Partida Najaf Amin Kathryn P Burdon Elisabeth M van Leeuwen Puya Gharahkhani Aniket Mishra Sven J van der Lee Alex W Hewitt Fernando Rivadeneira Ananth C Viswanathan Roger C W Wolfs Nicholas G Martin Wishal D Ramdas Leonieke M van Koolwijk Craig E Pennell Johannes R Vingerling Jenny E Mountain André G Uitterlinden Albert Hofman Paul Mitchell Hans G Lemij Jie Jin Wang Caroline C W Klaver David A Mackey Jamie E Craig Cornelia M van Duijn Stuart MacGregor

Hum Mol Genet 2015 May 30;24(9):2689-99. Epub 2015 Jan 30.

Statistical and

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http://hmg.oxfordjournals.org/content/24/9/2689.full.pdf
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddv027
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http://dx.doi.org/10.1093/hmg/ddv027DOI Listing
May 2015

Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology.

Authors:
Henriët Springelkamp Aniket Mishra Pirro G Hysi Puya Gharahkhani René Höhn Chiea-Chuen Khor Jessica N Cooke Bailey Xiaoyan Luo Wishal D Ramdas Eranga Vithana Victor Koh Seyhan Yazar Liang Xu Hannah Forward Lisa S Kearns Najaf Amin Adriana I Iglesias Kar-Seng Sim Elisabeth M van Leeuwen Ayse Demirkan Sven van der Lee Seng-Chee Loon Fernando Rivadeneira Abhishek Nag Paul G Sanfilippo Arne Schillert Paulus T V M de Jong Ben A Oostra André G Uitterlinden Albert Hofman Tiger Zhou Kathryn P Burdon Timothy D Spector Karl J Lackner Seang-Mei Saw Johannes R Vingerling Yik-Ying Teo Louis R Pasquale Roger C W Wolfs Hans G Lemij E-Shyong Tai Jost B Jonas Ching-Yu Cheng Tin Aung Nomdo M Jansonius Caroline C W Klaver Jamie E Craig Terri L Young Jonathan L Haines Stuart MacGregor David A Mackey Norbert Pfeiffer Tien-Yin Wong Janey L Wiggs Alex W Hewitt Cornelia M van Duijn Christopher J Hammond

Genet Epidemiol 2015 Mar 28;39(3):207-16. Epub 2015 Jan 28.

Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands.

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http://eprints.soton.ac.uk/369296/1/ncomms5883.pdf
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http://doi.wiley.com/10.1002/gepi.21886
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http://dx.doi.org/10.1002/gepi.21886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480365PMC
March 2015

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma.

Authors:
Pirro G Hysi Ching-Yu Cheng Henriët Springelkamp Stuart Macgregor Jessica N Cooke Bailey Robert Wojciechowski Veronique Vitart Abhishek Nag Alex W Hewitt René Höhn Cristina Venturini Alireza Mirshahi Wishal D Ramdas Gudmar Thorleifsson Eranga Vithana Chiea-Chuen Khor Arni B Stefansson Jiemin Liao Jonathan L Haines Najaf Amin Ya Xing Wang Philipp S Wild Ayse B Ozel Jun Z Li Brian W Fleck Tanja Zeller Sandra E Staffieri Yik-Ying Teo Gabriel Cuellar-Partida Xiaoyan Luo R Rand Allingham Julia E Richards Andrea Senft Lennart C Karssen Yingfeng Zheng Céline Bellenguez Liang Xu Adriana I Iglesias James F Wilson Jae H Kang Elisabeth M van Leeuwen Vesteinn Jonsson Unnur Thorsteinsdottir Dominiek D G Despriet Sarah Ennis Sayoko E Moroi Nicholas G Martin Nomdo M Jansonius Seyhan Yazar E-Shyong Tai Philippe Amouyel James Kirwan Leonieke M E van Koolwijk Michael A Hauser Fridbert Jonasson Paul Leo Stephanie J Loomis Rhys Fogarty Fernando Rivadeneira Lisa Kearns Karl J Lackner Paulus T V M de Jong Claire L Simpson Craig E Pennell Ben A Oostra André G Uitterlinden Seang-Mei Saw Andrew J Lotery Joan E Bailey-Wilson Albert Hofman Johannes R Vingerling Cécilia Maubaret Norbert Pfeiffer Roger C W Wolfs Hans G Lemij Terri L Young Louis R Pasquale Cécile Delcourt Timothy D Spector Caroline C W Klaver Kerrin S Small Kathryn P Burdon Kari Stefansson Tien-Yin Wong Ananth Viswanathan David A Mackey Jamie E Craig Janey L Wiggs Cornelia M van Duijn Christopher J Hammond Tin Aung

Nat Genet 2014 Oct 31;46(10):1126-1130. Epub 2014 Aug 31.

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.

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http://dx.doi.org/10.1038/ng.3087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177225PMC
October 2014

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process.

Authors:
Henriët Springelkamp René Höhn Aniket Mishra Pirro G Hysi Chiea-Chuen Khor Stephanie J Loomis Jessica N Cooke Bailey Jane Gibson Gudmar Thorleifsson Sarah F Janssen Xiaoyan Luo Wishal D Ramdas Eranga Vithana Monisha E Nongpiur Grant W Montgomery Liang Xu Jenny E Mountain Puya Gharahkhani Yi Lu Najaf Amin Lennart C Karssen Kar-Seng Sim Elisabeth M van Leeuwen Adriana I Iglesias Virginie J M Verhoeven Michael A Hauser Seng-Chee Loon Dominiek D G Despriet Abhishek Nag Cristina Venturini Paul G Sanfilippo Arne Schillert Jae H Kang John Landers Fridbert Jonasson Angela J Cree Leonieke M E van Koolwijk Fernando Rivadeneira Emmanuelle Souzeau Vesteinn Jonsson Geeta Menon Robert N Weinreb Paulus T V M de Jong Ben A Oostra André G Uitterlinden Albert Hofman Sarah Ennis Unnur Thorsteinsdottir Kathryn P Burdon Timothy D Spector Alireza Mirshahi Seang-Mei Saw Johannes R Vingerling Yik-Ying Teo Jonathan L Haines Roger C W Wolfs Hans G Lemij E-Shyong Tai Nomdo M Jansonius Jost B Jonas Ching-Yu Cheng Tin Aung Ananth C Viswanathan Caroline C W Klaver Jamie E Craig Stuart Macgregor David A Mackey Andrew J Lotery Kari Stefansson Arthur A B Bergen Terri L Young Janey L Wiggs Norbert Pfeiffer Tien-Yin Wong Louis R Pasquale Alex W Hewitt Cornelia M van Duijn Christopher J Hammond

Nat Commun 2014 Sep 22;5:4883. Epub 2014 Sep 22.

Department of Twin Research and Genetic Epidemiology, King's College London, London WC2R 2LS, UK.

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http://eprints.soton.ac.uk/369296/1/ncomms5883.pdf
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http://www.nature.com/doifinder/10.1038/ncomms5883
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http://dx.doi.org/10.1038/ncomms5883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199103PMC
September 2014

Scientific reporting is suboptimal for aspects that characterize genetic risk prediction studies: a review of published articles based on the Genetic RIsk Prediction Studies statement.

Authors:
Adriana I Iglesias Raluca Mihaescu John P A Ioannidis Muin J Khoury Julian Little Cornelia M van Duijn A Cecile J W Janssens

J Clin Epidemiol 2014 May 8;67(5):487-99. Epub 2014 Jan 8.

Department of Epidemiology, Emory University, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jclinepi.2013.10.006DOI Listing
May 2014

Exome sequencing and functional analyses suggest that SIX6 is a gene involved in an altered proliferation-differentiation balance early in life and optic nerve degeneration at old age.

Authors:
Adriana I Iglesias Henriët Springelkamp Herma van der Linde Lies-Anne Severijnen Najaf Amin Ben Oostra Christel E M Kockx Mirjam C G N van den Hout Wilfred F J van Ijcken Albert Hofman André G Uitterlinden Rob M Verdijk Caroline C W Klaver Rob Willemsen Cornelia M van Duijn

Hum Mol Genet 2014 Mar 22;23(5):1320-32. Epub 2013 Oct 22.

Department of Epidemiology.

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http://dx.doi.org/10.1093/hmg/ddt522DOI Listing
March 2014