Adrian V S Hill

Adrian V S Hill

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Adrian V S Hill

Adrian V S Hill

Publications by authors named "Adrian V S Hill"

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Common Genetic Variations Associated with the Persistence of Immunity following Childhood Immunization.

Cell Rep 2019 Jun;27(11):3241-3253.e4

Department of Paediatrics, University of Oxford, Oxford, UK; NIHR Oxford Biomedical Research Centre, Oxford, UK.

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http://dx.doi.org/10.1016/j.celrep.2019.05.053DOI Listing
June 2019

Publisher Correction: Adjuvanting a viral vectored vaccine against pre-erythrocytic malaria.

Sci Rep 2019 May 3;9(1):7060. Epub 2019 May 3.

The Jenner Institute, Nuffield Department of Medicine, University of Oxford, The Henry Wellcome Building for Molecular Physiology, Roosevelt Drive, Oxford, OX3 7BN, UK.

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http://dx.doi.org/10.1038/s41598-019-43120-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499826PMC
May 2019

DOPS Adjuvant Confers Enhanced Protection against Malaria for VLP-TRAP Based Vaccines.

Diseases 2018 Nov 21;6(4). Epub 2018 Nov 21.

The Jenner Institute, Nuffield Department of Medicine, Centre for Cellular and Molecular Physiology (CCMP), Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.3390/diseases6040107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313579PMC
November 2018

Development of a Molecular Adjuvant to Enhance Antigen-Specific CD8 T Cell Responses.

Sci Rep 2018 Oct 9;8(1):15020. Epub 2018 Oct 9.

The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford, United Kingdom.

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http://dx.doi.org/10.1038/s41598-018-33375-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177389PMC
October 2018

Vaccines against Ebola virus.

Vaccine 2018 08 2;36(36):5454-5459. Epub 2017 Aug 2.

Jenner Institute, University of Oxford, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom.

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http://dx.doi.org/10.1016/j.vaccine.2017.07.054DOI Listing
August 2018

Population Turnover in Remote Oceania Shortly after Initial Settlement.

Curr Biol 2018 04 28;28(7):1157-1165.e7. Epub 2018 Feb 28.

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Howard Hughes Medical Institute, Boston, MA 02115, USA; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Max Planck-Harvard Research Center for the Archaeoscience of the Ancient Mediterranean, Cambridge, MA 02138, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2018.02.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882562PMC
April 2018

Genetic variation in is associated with bacteremia secondary to diverse pathogens in African children.

Proc Natl Acad Sci U S A 2018 04 27;115(16):E3601-E3603. Epub 2018 Mar 27.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1802071115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910872PMC
April 2018

Chimpanzee adenoviral vectors as vaccines for outbreak pathogens.

Hum Vaccin Immunother 2017 12 30;13(12):3020-3032. Epub 2017 Oct 30.

a The Jenner Institute, University of Oxford , Old Road Campus Research Building, Headington , Oxford , UK.

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http://dx.doi.org/10.1080/21645515.2017.1383575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718829PMC
December 2017

Safety and immunogenicity of heterologous prime-boost immunization with viral-vectored malaria vaccines adjuvanted with Matrix-M™.

Vaccine 2017 10 21;35(45):6208-6217. Epub 2017 Sep 21.

Jenner Institute, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford OX3 7DQ, UK.

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http://dx.doi.org/10.1016/j.vaccine.2017.09.028DOI Listing
October 2017

Adjuvanting a viral vectored vaccine against pre-erythrocytic malaria.

Sci Rep 2017 08 4;7(1):7284. Epub 2017 Aug 4.

The Jenner Institute, Nuffield Department of Medicine, University of Oxford, The Henry Wellcome Building for Molecular Physiology, Roosevelt Drive, Oxford, OX3 7BN, UK.

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http://dx.doi.org/10.1038/s41598-017-07246-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544665PMC
August 2017

5T4 oncofoetal glycoprotein: an old target for a novel prostate cancer immunotherapy.

Oncotarget 2017 Jul;8(29):47474-47489

The Jenner Institute, University of Oxford, Roosevelt Drive Oxford, Oxford OX3 7DQ, United Kingdom.

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http://dx.doi.org/10.18632/oncotarget.17666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564579PMC
July 2017

Enhancing protective immunity to malaria with a highly immunogenic virus-like particle vaccine.

Sci Rep 2017 04 19;7:46621. Epub 2017 Apr 19.

The Jenner Institute Laboratories, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK.

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http://dx.doi.org/10.1038/srep46621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395940PMC
April 2017

Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28Day Mortality.

EBioMedicine 2016 Oct 15;12:239-246. Epub 2016 Sep 15.

Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany; Center for Clinical Studies, Jena University Hospital, Jena, Germany; Head of Paul-Martini-Clinical Sepsis Research Unit, Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.

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http://dx.doi.org/10.1016/j.ebiom.2016.08.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078589PMC
October 2016

Influence of adenovirus and MVA vaccines on the breadth and hierarchy of T cell responses.

Vaccine 2016 08 30;34(38):4470-4474. Epub 2016 Jul 30.

The Jenner Institute, University of Oxford, Roosevelt Drive, Oxford OX3 7DQ, United Kingdom.

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http://dx.doi.org/10.1016/j.vaccine.2016.07.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009894PMC
August 2016

A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA.

N Engl J Med 2016 Apr 28;374(17):1635-46. Epub 2015 Jan 28.

From the Jenner Institute and Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, and the National Institute for Health Research Oxford Biomedical Research Centre, Oxford (K.E., T.R., N.V., G.B., D.W., T.L., E.B.I., R.P., C.M.T., N.J.E., G.L., J.J., M.G., A.M., M.W., I.P., N.L., R.R., F.H., C.B., K.S.-D., J.P., E.B., A.J.P., S.J.D., A.L., S.C.G., A.V.S.H.), and Viral Pseudotype Unit, Faculty of Science and Technology, University of Westminster (E.M.B., E.W.), and Virus Reference Department, Public Health Agency (D.S., R.T.), London - all in the United Kingdom; the Institute of Virology, Philipps University Marburg (S.K.F., T.S., N.B., V.K., S.B.), and German Center for Infection Research, Partner Site Giessen-Marburg-Langen (S.B.), Marburg, and Bavarian Nordic, Martinsried (A.V., P.C.) - all in Germany; GlaxoSmithKline Biologicals, Rixensart, Belgium (F.R., I.D.R., W.R.B.); ReiThera, Rome (A.N., L.S., S.C., A.F., S.D.M.), and CEINGE and the Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples (A.N.) - both in Italy; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda (N.J.S., D.A.S., O.T.M., J.E.L., R.M.S., B.S.G., R.A.K.), and the Center for Vaccine Development, University of Maryland School of Medicine, Baltimore (M.M.L.) - both in Maryland; and Keires, Basel, Switzerland (R.C.).

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http://dx.doi.org/10.1056/NEJMoa1411627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798586PMC
April 2016

Potency of a thermostabilised chimpanzee adenovirus Rift Valley Fever vaccine in cattle.

Vaccine 2016 Apr 25;34(20):2296-8. Epub 2016 Mar 25.

The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK; Centre for Research on Therapeutic Sciences and, Institute for Healthcare Management Strathmore University, P.O. Box 59857-00200, Nairobi, Kenya. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2016.03.061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851241PMC
April 2016

Rare variants in MYD88, IRAK4 and IKBKG and susceptibility to invasive pneumococcal disease: a population-based case-control study.

PLoS One 2015 17;10(4):e0123532. Epub 2015 Apr 17.

Wellcome Trust Centre for Human Genetics, University of Oxford, United Kingdom; Oxford Centre for Respiratory Medicine, Churchill Hospital Site, Oxford University Hospitals, Oxford, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123532PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401548PMC
January 2016

Malaria vaccines: identifying Plasmodium falciparum liver-stage targets.

Front Microbiol 2015 15;6:965. Epub 2015 Sep 15.

The Jenner Institute, Nuffield Department of Medicine, University of Oxford Oxford, UK.

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http://dx.doi.org/10.3389/fmicb.2015.00965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569888PMC
October 2015

Transcriptional changes induced by candidate malaria vaccines and correlation with protection against malaria in a human challenge model.

Vaccine 2015 Sep 7;33(40):5321-31. Epub 2015 Aug 7.

London School of Hygiene & Tropical Medicine, London W1CE 7HT, UK; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.

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http://dx.doi.org/10.1016/j.vaccine.2015.07.087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582771PMC
September 2015

Profiling the host response to malaria vaccination and malaria challenge.

Vaccine 2015 Sep 6;33(40):5316-20. Epub 2015 Aug 6.

London School of Hygiene & Tropical Medicine, London, W1CE 7HT, UK; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.

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http://dx.doi.org/10.1016/j.vaccine.2015.07.107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582768PMC
September 2015

Design, recruitment, and microbiological considerations in human challenge studies.

Lancet Infect Dis 2015 Jul 27;15(7):840-51. Epub 2015 May 27.

Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK; National Institute of Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK.

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http://www.thelancet.com/pdfs/journals/laninf/PIIS1473-3099(
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http://linkinghub.elsevier.com/retrieve/pii/S147330991500068
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http://dx.doi.org/10.1016/S1473-3099(15)00068-7DOI Listing
July 2015

Genetic susceptibility to invasive Salmonella disease.

Nat Rev Immunol 2015 Jul;15(7):452-63

1] Wellcome Trust Centre for Human Genetics, Roosevelt Drive, University of Oxford, Oxford OX3 7BN, UK. [2] Jenner Institute, Nuffield Department of Medicine, Old Road Campus Research Building, Roosevelt Drive, University of Oxford, Oxford, OX3 7DQ, UK.

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http://dx.doi.org/10.1038/nri3858DOI Listing
July 2015

Genomic modulators of gene expression in human neutrophils.

Nat Commun 2015 Jul 7;6:7545. Epub 2015 Jul 7.

Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1038/ncomms8545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507005PMC
July 2015

Induction of CD8(+) T cell responses and protective efficacy following microneedle-mediated delivery of a live adenovirus-vectored malaria vaccine.

Vaccine 2015 Jun 1;33(28):3248-55. Epub 2015 Apr 1.

The Jenner Institute, University of Oxford, Roosevelt Drive, Oxford, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.03.039DOI Listing
June 2015

Searching for the human genetic factors standing in the way of universally effective vaccines.

Philos Trans R Soc Lond B Biol Sci 2015 Jun;370(1671)

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK Department of Paediatrics, University of Oxford, Oxford OX3 9DU, UK Oxford Biomedical Research Centre, Oxford OX3 7LE, UK.

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http://rstb.royalsocietypublishing.org/content/royptb/370/16
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http://rstb.royalsocietypublishing.org/cgi/doi/10.1098/rstb.
Publisher Site
http://dx.doi.org/10.1098/rstb.2014.0341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527396PMC
June 2015

Emergency Ebola response: a new approach to the rapid design and development of vaccines against emerging diseases.

Lancet Infect Dis 2015 Mar 14;15(3):356-9. Epub 2015 Jan 14.

Jenner Institute, University of Oxford, Oxford, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S14733099147107
Publisher Site
http://dx.doi.org/10.1016/S1473-3099(14)71071-0DOI Listing
March 2015

Next generation vaccines: single-dose encapsulated vaccines for improved global immunisation coverage and efficacy.

J Pharm Pharmacol 2015 Mar 2;67(3):400-8. Epub 2015 Feb 2.

ORCRB, The Jenner Institute, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1111/jphp.12367DOI Listing
March 2015

The association between the ratio of monocytes: lymphocytes and risk of tuberculosis among HIV-infected postpartum women.

J Acquir Immune Defic Syndr 2014 Dec;67(5):573-5

*Wellcome Trust Centre for Human Genetics Jenner Institute-Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; †Department of Obstetrics and Gynaecology, Center for the AIDS Programme of Research in South Africa, and Women's Health and HIV Research Unit, University of KwaZulu Natal, Durban, South Africa; ‡University of Zimbabwe College of Medicine Harare, Harare, Zimbabwe; §Department of Obstetrics and Gynaecology, Makerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda; ‖Department of Paediatrics, Makerere University, Kampala, Uganda; ¶Department of Paediatrics and Child Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania; #FHI 360, Research Triangle Park, School of Medicine, Durham, NC; **School of Medicine, Johns Hopkins University, Baltimore, MD; and ††Maternal Adolescent and Child Health, University of the Witwatersrand, Johannesburg, South Africa.

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http://dx.doi.org/10.1097/QAI.0000000000000353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229408PMC
December 2014

Microneedle-mediated immunization of an adenovirus-based malaria vaccine enhances antigen-specific antibody immunity and reduces anti-vector responses compared to the intradermal route.

Sci Rep 2014 Aug 21;4:6154. Epub 2014 Aug 21.

1] School of Pharmacy, University College Cork, Cork, Ireland [2] Dept. of Pharmacology and Therapeutics, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1038/srep06154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139947PMC
August 2014