Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss.
Genes Dev 2016 Jan 23;30(1):34-51. Epub 2015 Dec 23.
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA; Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, New York 11790, USA;

CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function.
Cell 2015 Aug;162(4):900-10
Center for Comparative Biomedicine, MOE Key Laboratory of Systems Biomedicine, Institute of Systems Biomedicine, Collaborative Innovation Center of Systems Biomedicine, Shanghai Jiao Tong University (SJTU), Shanghai 200240, China; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, School of Medicine, SJTU, Shanghai 200240, China; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (MOE), Bio-X Center, School of Life Sciences and Biotechnology, SJTU, Shanghai 200240, China. Electronic address:

RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease.
Science 2015 Jan 18;347(6218):1254806. Epub 2014 Dec 18.
Department of Electrical and Computer Engineering, University of Toronto, Toronto, Ontario M5S 3G4, Canada. Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada. Program on Genetic Networks and Program on Neural Computation & Adaptive Perception, Canadian Institute for Advanced Research, Toronto, Ontario M5G 1Z8, Canada. Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada. McLaughlin Centre, University of Toronto, Toronto, Ontario M5G 0A4, Canada. Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada. eScience Group, Microsoft Research, Redmond, WA 98052, USA.

Pharmacology of a central nervous system delivered 2'-O-methoxyethyl-modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primates.
J Pharmacol Exp Ther 2014 Jul 30;350(1):46-55. Epub 2014 Apr 30.
Isis Pharmaceuticals, Carlsbad, California (F.R., S.J.C., D.A.N., G.H., S.L., J.M., R.A.F., H.G., J.S.G., S.P.H., C.F.B.); and Cold Spring Harbor Laboratory, Cold Spring Harbor, New York (Y.H., A.R.K.).

HITS-CLIP and integrative modeling define the Rbfox splicing-regulatory network linked to brain development and autism.
Cell Rep 2014 Mar 6;6(6):1139-1152. Epub 2014 Mar 6.
Department of Systems Biology, Department of Biochemistry and Molecular Biophysics, Center for Motor Neuron Biology and Disease, Columbia University, New York, NY 10032, USA. Electronic address:

Alternative splicing in colon, bladder, and prostate cancer identified by exon array analysis.
Mol Cell Proteomics 2008 Jul 18;7(7):1214-24. Epub 2008 Mar 18.
Molecular Diagnostic Laboratory, Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, DK-8200 Aarhus N, Denmark.

Kaposi's sarcoma-associated herpesvirus ORF57 functions as a viral splicing factor and promotes expression of intron-containing viral lytic genes in spliceosome-mediated RNA splicing.
J Virol 2008 Mar 9;82(6):2792-801. Epub 2008 Jan 9.
HIV and AIDS Malignancy Branch, Center for Cancer Research, NCI/NIH, 10 Center Dr., Rm. 6N106, MSC-1868, Bethesda, MD 20892-1868, USA.

A novel histone exchange factor, protein phosphatase 2Cgamma, mediates the exchange and dephosphorylation of H2A-H2B.
J Cell Biol 2006 Nov 30;175(3):389-400. Epub 2006 Oct 30.
Nuclear Function and Dynamics Unit, Horizontal Medical Research Organization, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.

The switch in alternative splicing of cyclic AMP-response element modulator protein CREM{tau}2{alpha} (activator) to CREM{alpha} (repressor) in human myometrial cells is mediated by SRp40.
J Biol Chem 2005 Oct 15;280(41):34521-9. Epub 2005 Aug 15.
School of Surgical and Reproductive Sciences, 3rd Floor, William Leech Building, The Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne NE2 4HH, United Kingdom.

Manipulation of alternative splicing by a newly developed inhibitor of Clks.
J Biol Chem 2004 Jun 8;279(23):24246-54. Epub 2004 Mar 8.
Laboratory of Gene Expression, School of Biomedical Science, Department of Functional Genomics, Medical Research Institute, Tokyo Medical & Dental University, Japan.