Publications by authors named "Adrian P Wiegmans"

18Publications

Circulating Tumor Cells in Metastatic Breast Cancer: From Genome Instability to Metastasis.

Front Mol Biosci 2020 16;7:134. Epub 2020 Jul 16.

Cancer and Ageing Research Program, Institute of Health and Biomedical Innovation, Queensland University of Technology, Translational Research Institute, Woolongabba, QLD, Australia.

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http://dx.doi.org/10.3389/fmolb.2020.00134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378584PMC
July 2020

Breast Cancer-Derived Exosomes Alter Macrophage Polarization gp130/STAT3 Signaling.

Front Immunol 2018 8;9:871. Epub 2018 May 8.

Tumour Microenvironment Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.

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http://dx.doi.org/10.3389/fimmu.2018.00871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951966PMC
July 2019

Defects in recombination activity caused by somatic and germline mutations in the multimerization/BRCA2 binding region of human RAD51 protein.

DNA Repair (Amst) 2017 12 23;60:64-76. Epub 2017 Oct 23.

Department of Biochemistry, Larner College of Medicine at the University of Vermont, Burlington, VT 05405, United States; Department of Microbiology & Molecular Genetics, Larner College of Medicine at the University of Vermont, Burlington, VT 05405, United States; University of Vermont Cancer Center, Burlington, VT 05405, United States. Electronic address:

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http://dx.doi.org/10.1016/j.dnarep.2017.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699509PMC
December 2017

Quinazolinone derivatives as inhibitors of homologous recombinase RAD51.

Bioorg Med Chem Lett 2017 07 15;27(14):3096-3100. Epub 2017 May 15.

Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.05.039DOI Listing
July 2017

Differences in Expression of Key DNA Damage Repair Genes after Epigenetic-Induced BRCAness Dictate Synthetic Lethality with PARP1 Inhibition.

Mol Cancer Ther 2015 Oct 20;14(10):2321-31. Epub 2015 Aug 20.

Signal Transduction Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0374DOI Listing
October 2015

Optimized exosome isolation protocol for cell culture supernatant and human plasma.

J Extracell Vesicles 2015 17;4:27031. Epub 2015 Jul 17.

Tumour Microenvironment Laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507751PMC
http://dx.doi.org/10.3402/jev.v4.27031DOI Listing
July 2015

Targeting homologous recombination, new pre-clinical and clinical therapeutic combinations inhibiting RAD51.

Cancer Treat Rev 2015 Jan 1;41(1):35-45. Epub 2014 Nov 1.

Signal Transduction Laboratory, QIMR Berghofer, Herston Rd, Herston, QLD 4006, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2014.10.006DOI Listing
January 2015

Rad51 supports triple negative breast cancer metastasis.

Oncotarget 2014 May;5(10):3261-72

QIMR Berghofer Medical Research Institute, Signal Transduction Laboratory, Herston Rd, Herston QLD 4006, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102808PMC
http://dx.doi.org/10.18632/oncotarget.1923DOI Listing
May 2014

Deciphering the molecular events necessary for synergistic tumor cell apoptosis mediated by the histone deacetylase inhibitor vorinostat and the BH3 mimetic ABT-737.

Cancer Res 2011 May 11;71(10):3603-15. Epub 2011 Mar 11.

Gene Regulation Laboratory, Cancer Therapeutics Program, The Peter MacCallum Cancer Institute, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-3289DOI Listing
May 2011